pimagedine has been researched along with lysine in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 27 (43.55) | 18.2507 |
| 2000's | 27 (43.55) | 29.6817 |
| 2010's | 6 (9.68) | 24.3611 |
| 2020's | 2 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Audic, N; Ermolenko, L; Franck, G; Garcia-Alvarez, MC; Martin, MT; Nhiri, N; Potier, P; Sasaki, NA; Wang, Q | 1 |
| Smith, PR; Thornalley, PJ | 1 |
| Acharya, AS; Dorai, B; Roy, RP | 1 |
| Charonis, AS; Dege, JE; Furcht, LT; Kouzi-Koliakos, K; Reger, LA; Tsilibary, EC; Wohlhueter, RM | 1 |
| Connor, JR; Currie, MG; Jerome, GM; Manning, PT; Moore, WM; Settle, SL; Tjoeng, FS; Webber, RK | 1 |
| Ortwerth, BJ; Prabhakaram, M | 1 |
| Monnier, V | 1 |
| Cabezas-Cerrato, J; Requena, JR; Vidal, P | 1 |
| Archer, DB; Chakravarthy, U; Gardiner, TA; Stitt, AW | 1 |
| Bourdon, DM; Currie, MG; Manning, PT; Marino, MH; Salvemini, D; Wang, ZQ; Wyatt, PS | 1 |
| Nerlich, AG; Schleicher, ED; Wagner, E | 1 |
| Allen, PC; Clark, DA; Connor, JR; Currie, MG; Didier, P; Manning, PT; Miller, MJ; Ratterree, MS; Ribbons, KA | 1 |
| Brain, SD; Bryant, CE; Pettipher, ER; Ridger, VC | 1 |
| Hitsumoto, Y; Murase, M; Saheki, S; Shishino, K; Takeuchi, N; Uchida, K | 1 |
| Iqbal, M; Klandorf, H; Probert, LL | 1 |
| Bryk, R; Wolff, DJ | 1 |
| Gugliucci, A; Menini, T | 1 |
| Kurokawa, K; Mitsuma, T; Miyata, T; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Yasuda, Y | 1 |
| Gauld, DS; Lubeskie, A; Neulander, MJ; Wolff, DJ | 1 |
| Izuhara, Y; Jadoul, M; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; van Ypersele de Strihou, C; Wada, T; Yamada, Y | 1 |
| Alhumadi, NH; Iqbal, M; Klandorf, H; Probert, LL | 1 |
| Baynes, JW; Degenhardt, TP; Fu, MX; Neidlein, R; Reiff, K; Reiter, R; Strein, K; Thorpe, SR; Voss, E | 1 |
| Jones, RB; Simpson, AE | 1 |
| Bao, M; Li, D; Li, YM; Song, X | 1 |
| Monnier, VM; Saxena, AK; Weiss, MF | 1 |
| Bryk, R; Lubeskie, A; Wolff, DJ | 1 |
| Billiar, TR; Carcillo, JA; Carlos, TM; Chen, M; Clark, RS; DeKosky, ST; Dixon, CE; Kochanek, PM; Marion, DW; Schiding, JK; Sinz, EH; Watkins, SC; Williams, D; Wisniewski, SR | 1 |
| Iqbal, M; Kenney, PB; Klandorf, H | 1 |
| Araki, A; Deoreo, PB; Erhard, P; Glomb, MA; Kader-Attia, FA; Monnier, VM; Weiss, MF; Wu, YC | 1 |
| Arakawa, K; Horiuchi, S; Imanaga, Y; Itabe, H; Matsunaga, A; Nagai, R; Sakata, N; Sasaki, J; Takano, T; Takebayashi, S | 1 |
| Billiau, A; Matthys, P; Thielemans, L; Vermeire, K | 1 |
| Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C | 1 |
| Al-Humadi, NH; Iqbal, M; Kenney, PB; Klandorf, H | 1 |
| Horiuchi, S; Itabe, H; Jono, T; Myint, T; Nagai, R; Sakata, N; Takano, T; Takebayashi, S; Takeya, M; Taniguchi, N; Uesugi, N | 1 |
| Engerman, RL; Kern, TS | 1 |
| Imai, A; Kohno, S; Mizutani, N; Nabe, T; Sakurai, H; Takenaka, H | 1 |
| Bucci, TJ; Hinson, JA; Irwin, LK; Mayeux, PR; Michael, SL | 1 |
| Coppey, LJ; Davidson, EP; Dunlap, JA; Gellett, JS; Yorek, MA | 1 |
| Amano, S; Horiuchi, S; Kaji, Y; Nagai, R; Oshika, T; Suzuki, K; Tanaka, S; Usui, T | 1 |
| Araki, T; Hayase, F; Horiuchi, S; Miki Hayashi, C; Miyazaki, K; Nagai, R; Ono, T | 1 |
| Hayase, F; Hayashi, MC; Horiuchi, S; Kinae, N; Masuda, S; Nagai, R; Unno, Y | 1 |
| Brammar, G; Burns, WC; Cao, Z; Cooper, ME; Forbes, JM; MCLennan, SV; Twigg, SM | 1 |
| Ejiri, Y; Tanaka, K; Yamauchi, Y | 1 |
| Gerrard, JA; Meade, SJ; Miller, AG | 1 |
| Funk, RH; Geffarth, R; Kasper, M; Reber, F; Reichenbach, A; Schleicher, ED; Siegner, A | 1 |
| Ferreira, AE; Ponces Freire, AM; Voit, EO | 1 |
| Grigorova-Borsos, AM; Sternberg, M; Urios, P | 1 |
| Ishii, K; Kubota, Y; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Yonoki, Y | 1 |
| Jafarian-Tehrani, M; Louin, G; Marchand-Verrecchia, C; Palmier, B; Plotkine, M | 1 |
| Machado, AP; Moysés, ZP; Nakandakare, ER; Passarelli, M; Pinto, RS; Quintão, EC | 1 |
| Fierer, J; Jimenez, Mdel P; Walls, L | 1 |
| Kang, KS; Kim, HY; Yamabe, N; Yokozawa, T | 1 |
| Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J | 1 |
| Boengler, K; Duschin, A; Gres, P; Heinzel, FR; Heusch, G; Kelm, M; Konietzka, I; Meyer, S; Rassaf, T; Schulz, R; Skyschally, A; Snedovskaya, J | 1 |
| Anderson, G; Baumann, M; Heemann, U; Hermans, R; Lutz, J; Schmaderer, C; Xing, CJ | 1 |
| Bloemen, JG; Buurman, WA; Dejong, CH; Driessen, A; Gaens, KH; Greve, JW; Hofker, MH; Niessen, PM; Rensen, SS; Schalkwijk, CG; Stehouwer, CD; Wolfs, MG | 1 |
| Choe, J; Ha, KS; Jeoung, D; Kim, YM; Kwon, YG; Lee, DK; Lee, H; Lee, KS; Won, MH | 1 |
| Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J | 1 |
| Chen, G; Chen, H; Chen, XM; Kitts, DD; Zhang, Y | 1 |
| André-Frei, V; Bechetoille, N; Berthod, F; Cadau, S; Leoty-Okombi, S; Pain, S | 1 |
| Ahmad, S; Akashah, R; Alouffi, S; Faisal, M; Khan, M; Khan, MS; Khan, S; Shahab, U | 1 |
| Inoue, Y; Iwai, M; Kadoyama, K; Matsumoto, K; Nitta, Y; Takano-Ohmuro, H; Takasugi, R; Takenokuchi, M; Taniguchi, T; Yoshida, K | 1 |
1 review(s) available for pimagedine and lysine
| Article | Year |
|---|---|
[Non-enzymatic glycosylation of proteins. Complications of diabetes mellitus, aging and kidney failure].
Topics: Aging; Arginine; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Lysine; Maillard Reaction; Renal Insufficiency | 1993 |
1 trial(s) available for pimagedine and lysine
| Article | Year |
|---|---|
Relationship between mechanical properties and pentosidine in tendon: effects of age, diet restriction, and aminoguanidine in broiler breeder hens.
Topics: Aging; Animals; Arginine; Biomechanical Phenomena; Chickens; Diet; Elasticity; Female; Food Deprivation; Guanidines; Lysine; Regression Analysis; Tendons; Tensile Strength | 2000 |
60 other study(ies) available for pimagedine and lysine
| Article | Year |
|---|---|
N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.
Topics: beta-Alanine; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Magnetic Resonance Spectroscopy; Peptides; Pyruvaldehyde | 2009 |
Mechanism of the degradation of non-enzymatically glycated proteins under physiological conditions. Studies with the model fructosamine, N epsilon-(1-deoxy-D-fructos-1-yl)hippuryl-lysine.
Topics: Anaerobiosis; Catalase; Deferoxamine; Fructosamine; Glycoproteins; Glycosylation; Guanidines; Hexosamines; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Superoxide Dismutase | 1992 |
Aldimine to ketoamine isomerization (Amadori rearrangement) potential at the individual nonenzymic glycation sites of hemoglobin A: preferential inhibition of glycation by nucleophiles at sites of low isomerization potential.
Topics: Binding Sites; Glycated Hemoglobin; Glyceraldehyde; Glycine; Glycosylation; Guanidines; Hemoglobin A; Hexosamines; Hydrogen-Ion Concentration; Imines; Isomerism; Kinetics; Lysine; Tromethamine; Valine | 1991 |
Laminin alterations after in vitro nonenzymatic glycosylation.
Topics: Animals; Basement Membrane; Glucose; Glycosylation; Guanidines; Kinetics; Laminin; Lysine; Mice; Neoplasms, Experimental; Nephelometry and Turbidimetry | 1990 |
Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arthritis, Experimental; Blood Pressure; Enzyme Induction; Guanidines; Immunohistochemistry; Joints; Lysine; Male; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred Lew; Synovial Fluid | 1995 |
Determination of glycation crosslinking by the sugar-dependent incorporation of [14C]lysine into protein.
Topics: Amino Acids; Ascorbic Acid; Carbohydrate Metabolism; Carbon Radioisotopes; Cross-Linking Reagents; Glycosylation; Guanidines; Kinetics; Lysine; Oxidation-Reduction; Proteins | 1994 |
Aminoguanidine inhibits protein browning without extensive Amadori carbonyl blocking.
Topics: Animals; Cattle; Fluorescence; Fructosamine; Glycation End Products, Advanced; Guanidines; Hexosamines; Lysine; Maillard Reaction; Serum Albumin, Bovine | 1993 |
Increased endocytosis in retinal vascular endothelial cells grown in high glucose medium is modulated by inhibitors of nonenzymatic glycosylation.
Topics: Animals; Capillaries; Cattle; Cell Division; Cells, Cultured; Endocytosis; Endothelium; Enzyme Inhibitors; Female; Glucose; Glycosylation; Guanidines; Horseradish Peroxidase; Lysine; Retinal Vessels | 1995 |
Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation.
Topics: Animals; Carrageenan; Dinoprostone; Edema; Enzyme Inhibitors; Excipients; Free Radical Scavengers; Guanidines; Hindlimb; Inflammation; Isoenzymes; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1996 |
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E | 1997 |
The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey.
Topics: Administration, Oral; Animals; Colitis, Ulcerative; Colon; Enzyme Inhibitors; Feces; Guanidines; Inflammation; Intestinal Mucosa; Lysine; Macaca mulatta; Nitric Oxide Synthase | 1997 |
Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Humans; Inflammation; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Skin; Zymosan | 1997 |
Decreased susceptibility of glycated very low density lipoproteins to lipoprotein lipase in vitro and prevention by glutathione.
Topics: Catalysis; Enzyme Inhibitors; Fatty Acids; Glutathione; Glycosylation; Guanidines; Humans; Hydrolysis; Lipoprotein Lipase; Lipoproteins, VLDL; Lysine; Oxidation-Reduction; Stereoisomerism; Substrate Specificity | 1994 |
Effect of dietary aminoguanidine on tissue pentosidine and reproductive performance in broiler breeder hens.
Topics: Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Chickens; Collagen; Diet; Egg Shell; Female; Fertility; Guanidines; Lysine; Male; Oviposition; Random Allocation; Reproduction; Skin; Specific Gravity | 1997 |
Mechanism of inducible nitric oxide synthase inactivation by aminoguanidine and L-N6-(1-iminoethyl)lysine.
Topics: Animals; Carbon Isotopes; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Guanidines; Kinetics; Lysine; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Spectrometry, Fluorescence | 1998 |
Circulating advanced glycation peptides in streptozotocin-induced diabetic rats: evidence for preferential modification of IgG light chains.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Guanidines; Immunoglobulin Light Chains; Lysine; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1998 |
Accelerated formation of N epsilon-(carboxymethyl) lysine, an advanced glycation end product, by glyoxal and 3-deoxyglucosone in cultured rat sensory neurons.
Topics: Animals; Apoptosis; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycation End Products, Advanced; Glyoxal; Guanidines; Lysine; Neurons, Afferent; Rats; Rats, Sprague-Dawley | 1998 |
Inactivation of nitric oxide synthases and cellular nitric oxide formation by N6-iminoethyl-L-lysine and N5-iminoethyl-L-ornithine.
Topics: Animals; Cytokines; Enzyme Inhibitors; Guanidines; Isoenzymes; Kinetics; Lysine; Methemoglobin; Mice; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Oxyhemoglobins | 1998 |
Accumulation of carbonyls accelerates the formation of pentosidine, an advanced glycation end product: carbonyl stress in uremia.
Topics: Aged; Aldehydes; Arginine; Carboxylic Acids; Deoxyglucose; Depression, Chemical; Esters; Glycosylation; Guanidines; Humans; Ketones; Lysine; Maillard Reaction; Male; Middle Aged; Molecular Weight; Phenylhydrazines; Renal Dialysis; Thiadiazoles; Thiazolidines; Ultrafiltration; Uremia | 1998 |
Protein glycosylation and advanced glycosylated endproducts (AGEs) accumulation: an avian solution?
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Enzyme Inhibitors; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Hyperglycemia; Leukocytes; Lysine; Oxidative Stress; Random Allocation; Respiratory Burst; Skin; Uric Acid | 1999 |
Aminoguanidine inhibits albuminuria, but not the formation of advanced glycation end-products in skin collagen of diabetic rats.
Topics: Albuminuria; Animals; Arginine; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glycated Hemoglobin; Glycation End Products, Advanced; Guanidines; Kinetics; Lysine; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Lew; Reference Values; Skin | 1999 |
The effect of an insulin releasing agent, BTS 67582, on advanced glycation end product formation in vitro.
Topics: Ferrous Compounds; Glucose; Glucose-6-Phosphate; Glyburide; Glycation End Products, Advanced; Guanidines; Lysine; Serum Albumin, Bovine; Tolbutamide | 1999 |
Advanced glycation in D-galactose induced mouse aging model.
Topics: Aging; Animals; Avoidance Learning; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Female; Galactose; Glucose; Glycation End Products, Advanced; Guanidines; Hydroxyproline; Interleukin-2; Learning; Lymphocytes; Lysine; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Nervous System Diseases; Skin; Superoxide Dismutase | 1999 |
Pharmacological modulation of AGEs: a unique role for redox-active metal ions.
Topics: Animals; Antioxidants; Chelating Agents; Diabetes Mellitus; Glycation End Products, Advanced; Guanidines; Humans; Kidney Failure, Chronic; Lysine; Metals; Oxidation-Reduction; Oxidative Stress; Peritoneal Dialysis; Uremia | 1999 |
Studies of neuronal nitric oxide synthase inactivation by diverse suicide inhibitors.
Topics: Arginine; Catalytic Domain; Dimerization; Dose-Response Relationship, Drug; Guanidines; Hemeproteins; Lysine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Ornithine; Protein Structure, Quaternary | 1999 |
Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice.
Topics: Animals; Brain Damage, Chronic; Brain Injuries; Cognition Disorders; Enzyme Induction; Enzyme Inhibitors; Guanidines; Hippocampus; Hypoxia; Lysine; Male; Maze Learning; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Whole-Body Irradiation; Wounds, Nonpenetrating | 1999 |
Age-related changes in meat tenderness and tissue pentosidine: effect of diet restriction and aminoguanidine in broiler breeder hens.
Topics: Age Factors; Animal Feed; Animals; Arginine; Chickens; Cross-Linking Reagents; Diet; Female; Guanidines; Lysine; Meat | 1999 |
Mechanisms for the formation of glycoxidation products in end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Enzyme Inhibitors; Female; Glucose; Glycation End Products, Advanced; Guanidines; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Male; Middle Aged; Oxidation-Reduction; Peritoneal Dialysis; Renal Dialysis | 2000 |
In vivo and in vitro evidence for the glycoxidation of low density lipoprotein in human atherosclerotic plaques.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Aortic Diseases; Arteriosclerosis; Chelating Agents; Child; Child, Preschool; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Infant; Lipoproteins, LDL; Lysine; Male; Middle Aged; Nitric Oxide Synthase; Phosphatidylcholines; Thiobarbituric Acid Reactive Substances | 2000 |
The effects of NO synthase inhibitors on murine collagen-induced arthritis do not support a role of NO in the protective effect of IFN-gamma.
Topics: Administration, Oral; Animals; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genetic Predisposition to Disease; Guanidines; Interferon gamma Receptor; Interferon-gamma; Lysine; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Receptors, Interferon; Weight Loss | 2000 |
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines | 2000 |
Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Chelating Agents; Copper; Edetic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Guanidines; Humans; Immunohistochemistry; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Male; Malondialdehyde; Middle Aged; Pentetic Acid; Receptors, Immunologic; Receptors, Scavenger | 2001 |
Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin.
Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dogs; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosuria; Guanidines; Kidney; Lysine; Neural Conduction; Platelet Aggregation; Random Allocation; Retinal Vessels; Ulnar Nerve | 2001 |
Involvement of nitric oxide in pollen-induced biphasic nasal blockage in sensitised guinea pigs.
Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Allergens; Animals; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Guinea Pigs; Injections, Intravenous; Lysine; Male; Naphazoline; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pollen; Rhinitis, Allergic, Seasonal; Sneezing; Time Factors | 2001 |
Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Drug Interactions; Enzyme Inhibitors; Guanidines; Liver; Lysine; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 2002 |
Effect of treating streptozotocin-induced diabetic rats with sorbinil, myo-inositol or aminoguanidine on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve.
Topics: Aldehyde Reductase; Animals; Arginine; Arterioles; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Guanidines; Imidazoles; Imidazolidines; Inositol; Lysine; Male; Neural Conduction; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Superoxides | 2002 |
Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell.
Topics: Animals; Antibodies, Monoclonal; Cattle; Cell Adhesion; Cell Division; Cells, Cultured; Collagen Type I; Collagen Type IV; Descemet Membrane; Endothelium, Corneal; Enzyme-Linked Immunosorbent Assay; Fibronectins; Glycation End Products, Advanced; Glycosylation; Guanidines; Immunoenzyme Techniques; Laminin; Lysine | 2001 |
Conversion of Amadori products of the Maillard reaction to N(epsilon)-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry.
Topics: Animals; Antibodies, Monoclonal; Artifacts; Borohydrides; Glycation End Products, Advanced; Guanidines; Hot Temperature; Humans; Immunoenzyme Techniques; Liver; Lysine; Maillard Reaction; Male; Polyamines; Rats; Rats, Wistar; Serum Albumin; Skin | 2002 |
Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite.
Topics: 2-Naphthylamine; Aldehydes; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glucose; Glyoxal; Guanidines; Ketoses; Lysine; Mice; Mice, Inbred BALB C; Peroxynitrous Acid; Serum Albumin; Tyrosine | 2002 |
Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine.
Topics: Animals; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Gene Expression; Glomerular Mesangium; Glycation End Products, Advanced; Guanidines; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin, Bovine | 2002 |
Glycation by ascorbic acid causes loss of activity of ribulose-1,5-bisphosphate carboxylase/oxygenase and its increased susceptibility to proteases.
Topics: Ascorbic Acid; Blotting, Western; Carbon Radioisotopes; Chymotrypsin; Endopeptidases; Enzyme Stability; Glutathione; Glycation End Products, Advanced; Guanidines; Immunochemistry; Lysine; Ribulose-Bisphosphate Carboxylase | 2002 |
New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics.
Topics: Aging; Animals; Catalysis; Cattle; Cross-Linking Reagents; Dimyristoylphosphatidylcholine; Electrophoresis, Polyacrylamide Gel; Guanidines; Indicators and Reagents; Lysine; Maillard Reaction; Methylene Blue; Renin; Ribonuclease, Pancreatic; Somatostatin | 2003 |
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glyoxal; Guanidines; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lysine; Male; Neurons; Niacinamide; Organ Culture Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Thioctic Acid; Vanadates | 2003 |
A quantitative model of the generation of N(epsilon)-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose.
Topics: Collagen; Glucose; Glycation End Products, Advanced; Guanidines; Kinetics; Lysine; Maillard Reaction; Models, Theoretical | 2003 |
Unexpected elevation of pentosidine formation in collagen incubated with glucose by low concentrations of the AGE-inhibitor aminoguanidine.
Topics: Animals; Arginine; Cattle; Collagen; Glucose; Glycation End Products, Advanced; Guanidines; Kinetics; Lysine | 2004 |
Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina.
Topics: Animals; Enzyme Inhibitors; Guanidines; Indazoles; Ischemia; Ischemic Preconditioning; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitroarginine; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels | 2006 |
Selective inhibition of inducible nitric oxide synthase reduces neurological deficit but not cerebral edema following traumatic brain injury.
Topics: Amidines; Animals; Benzylamines; Blood-Brain Barrier; Body Water; Brain Edema; Brain Injuries; Enzyme Inhibitors; Guanidines; Lysine; Male; Nervous System Diseases; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2006 |
Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products.
Topics: Albumins; Animals; Atherosclerosis; Cells, Cultured; Cholesterol, HDL; Diabetes Mellitus; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Humans; Hypoglycemic Agents; Lysine; Macrophages, Peritoneal; Metformin; Mice | 2006 |
High levels of interleukin-10 impair resistance to pulmonary coccidioidomycosis in mice in part through control of nitric oxide synthase 2 expression.
Topics: Animals; Coccidioidomycosis; Female; Gene Expression Regulation, Enzymologic; Guanidines; Interleukin-10; Interleukin-4; Lung Diseases, Fungal; Lysine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Nitric Oxide Synthase Type II; RNA, Messenger | 2006 |
Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glycated Serum Albumin; Glycation End Products, Advanced; Guanidines; Lysine; Male; Proteinuria; Pyrones; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Streptozocin; Transcription Factor RelA | 2008 |
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan | 2008 |
Inducible nitric oxide synthase expression and cardiomyocyte dysfunction during sustained moderate ischemia in pigs.
Topics: Acute Disease; Animals; Arginine; Calcium; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Lysine; Myocardial Ischemia; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Signal Transduction; Swine; Swine, Miniature | 2008 |
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiotonic Agents; Dinoprost; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Hydroxyproline; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Lysine; Male; Oxidative Stress; Proteinuria; Rats; Rats, Inbred F344; Rats, Inbred Lew; Tetrazoles; Time Factors; Transplantation, Homologous | 2011 |
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.
Topics: Aged; Biomarkers; Biopsy; Cytokines; Enzyme Inhibitors; Fatty Liver; Female; Gene Expression; Guanidines; Hep G2 Cells; Hepatocytes; Humans; In Vitro Techniques; Liver; Lysine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Pyridoxamine; Vitamin B Complex | 2012 |
Differential effects of substrate-analogue inhibitors on nitric oxide synthase dimerization.
Topics: Animals; Cell Line; Enzyme Inhibitors; Guanidines; Lysine; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Protein Multimerization; Substrate Specificity | 2012 |
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels | 2013 |
Elucidation of the chemical structure and determination of the production conditions for a bioactive Maillard reaction product, [5-(5,6-dihydro-4H-pyridin-3-ylidenemethyl)furan-2-yl]methanol, isolated from a glucose-lysine heated mixture.
Topics: Caco-2 Cells; Dihydropyridines; Furans; Glucose; Guanidines; Hot Temperature; Humans; Lysine; Maillard Reaction; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrrolidines; Thiocarbamates | 2015 |
In vitro glycation of an endothelialized and innervated tissue-engineered skin to screen anti-AGE molecules.
Topics: Animals; Capillaries; Cattle; Cell Differentiation; Cells, Cultured; Collagen; Cytoskeleton; Dermis; Endothelial Cells; Fibroblasts; Filaggrin Proteins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Guanidines; Humans; Keratinocytes; Lysine; Mice; Neurons; Protective Agents; Skin; Thiazoles; Tissue Engineering | 2015 |
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Glycosylation; Gold; Guanidines; Lysine; Male; Metal Nanoparticles; Proteins; Pyruvaldehyde; Rats; Rats, Wistar | 2021 |
In Vitro and In Vivo Antiglycation Effects of Connarus ruber Extract.
Topics: Animals; Arginine; Collagen; Connaraceae; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guanidines; Lipids; Lysine; Pyruvaldehyde; Rats; Streptozocin | 2022 |