pimagedine has been researched along with cpu0213 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, DZ; Dai, Y; Liu, HR; Na, T; Su, W | 1 |
| Dai, DZ; Dai, Y; Li, N; Xu, J; Yu, F | 1 |
| Cheng, YS; Dai, DZ; Dai, Y | 1 |
3 other study(ies) available for pimagedine and cpu0213
| Article | Year |
|---|---|
Upregulated endothelin system in diabetic vascular dysfunction and early retinopathy is reversed by CPU0213 and total triterpene acids from Fructus Corni.
Topics: Animals; Aorta, Thoracic; Aspartic Acid Endopeptidases; Cornus; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelin A Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Guanidines; Male; Metalloendopeptidases; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Retina; RNA, Messenger; Thoracic Arteries; Triterpenes; Up-Regulation; Vasodilation | 2007 |
The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature.
Topics: Animals; Aorta, Thoracic; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Guanidines; In Vitro Techniques; Isoproterenol; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Up-Regulation | 2008 |
Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213.
Topics: Animals; Cardiotonic Agents; Endothelin Receptor Antagonists; Gene Expression Regulation; Guanidines; Heart; Hypertrophy; Isoproterenol; Male; Matrix Metalloproteinase 9; Myocardium; NADPH Oxidases; Nitric Oxide Synthase; Protein Kinase C-epsilon; Pyrazoles; Rats; Rats, Sprague-Dawley | 2009 |