pilsicainide has been researched along with mexiletine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Arita, M; Kiyosue, T; Sato, T; Wu, B | 1 |
| Kato, R; Koide, M; Miyahara, T; Sotobata, I; Toyama, J; Ukai, M; Yasui, S; Yokota, M | 1 |
| Handa, S; Ogawa, S; Okada, Y; Sadanaga, T | 1 |
| Ikeda, N; Kamiya, K | 1 |
| Aisaka, K; Hattori, Y; Hidaka, T; Ishihara, T; Satoh, F | 1 |
| Hattori, Y; Ishihara, T; Kodama, I; Kusunoki, T; Toyama, J; Yamada, K | 1 |
| Hashimoto, Y; Hatta, M; Hattori, Y; Hirotsu, I; Ishihara, T; Kihara, T; Kitakaze, Y; Miyata, T; Nakamura, S; Takahama, K | 1 |
| Hatta, M; Hattori, Y; Hirose, N; Hirotsu, I; Ishihara, T; Kihara, T; Satoh, F | 1 |
| Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T; Yamahara, Y | 1 |
| Akaishi, M; Handa, S; Iwanaga, S; Ogawa, S; Okada, Y; Sadanaga, T; Tsutsumi, N; Yoshikawa, T | 1 |
| Arita, M; Sato, T; Shigematsu, S | 1 |
| Ando, A; Hirai, M; Inden, Y; Isobe, S; Murohara, T; Nonokawa, M; Okada, M; Suzuki, A; Takada, Y; Tomita, Y | 1 |
| Imaki, R; Inuo, K; Izumi, T; Morohoshi, Y; Nakayama, S; Niwano, S; Yuge, M | 1 |
| Bruno, C; Conte Camerino, D; Costanza, T; Desaphy, JF; Dipalma, A; Franchini, C; George, A; Lentini, G | 1 |
2 trial(s) available for pilsicainide and mexiletine
| Article | Year |
|---|---|
Kinetics of frequency-dependent conduction delay by class I antiarrhythmic drugs in human atrium.
Topics: Anti-Arrhythmia Agents; Aprindine; Cardiac Pacing, Artificial; Disopyramide; Electrophysiology; Female; Heart Atria; Heart Conduction System; Humans; Kinetics; Lidocaine; Male; Mexiletine; Middle Aged; Sodium Channels | 1995 |
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart Ventricles; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Radionuclide Imaging; Tachycardia, Ventricular; Treatment Outcome; Ventricular Dysfunction, Left | 2004 |
13 other study(ies) available for pilsicainide and mexiletine
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs.
Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Dinitrophenols; Disopyramide; Flecainide; Glyburide; Guinea Pigs; Heart Ventricles; Imidazoles; Lidocaine; Mexiletine; Myocardium; Piperidines; Potassium; Procainamide; Pyridines | 1992 |
[Pharmacokinetics and pharmacodynamics of class I antiarrhythmic agents after a single oral administration].
Topics: Administration, Oral; Anti-Arrhythmia Agents; Aprindine; Flecainide; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone | 1992 |
[Clinical significance of the use-dependent sodium channel block and reverse use-dependent potassium channel block of class I and class III antiarrhythmic agents and their values to predict drug efficacy].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography, Ambulatory; Electrophysiology; Exercise Test; Humans; Lidocaine; Mexiletine; Middle Aged; Potassium Channels; Sodium Channels | 1992 |
[Estimation of depressant effects of class I antiarrhythmic drugs on intraventricular conduction--rate-dependent effects on QRS duration].
Topics: Anti-Arrhythmia Agents; Aprindine; Depression, Chemical; Disopyramide; Electrocardiography; Flecainide; Heart Conduction System; Heart Rate; Humans; Lidocaine; Mexiletine; Sodium Channels; Ventricular Function | 1992 |
Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles.
Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Disopyramide; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Ion Channels; Lidocaine; Male; Mexiletine; Papillary Muscles; Piperidines; Sodium | 1988 |
Use-dependent blocking action of newly developed lidocaine-analogs on maximum rate of rise of action potentials in guinea pig papillary muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Depression, Chemical; Guinea Pigs; Kinetics; Lidocaine; Mexiletine; Papillary Muscles; Structure-Activity Relationship; Tocainide | 1987 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Body Temperature; Catalepsy; Cats; Central Nervous System; Chemical Phenomena; Chemistry; Disopyramide; Dogs; Electroencephalography; Female; Hypothermia; Lidocaine; Male; Mexiletine; Mice; Motor Activity; Muscle Relaxation; Pain; Rabbits; Rats; Rats, Inbred Strains; Seizures; Tremor; Vomiting | 1988 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 2nd communication: effect on the peripheral nervous system and peripheral organs.
Topics: Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Capillary Permeability; Chemical Phenomena; Chemistry; Digestive System; Disopyramide; Endocrine Glands; Female; Gastric Mucosa; Gastrointestinal Motility; Guinea Pigs; Ileum; Lidocaine; Male; Mexiletine; Mice; Peripheral Nerves; Pregnancy; Pupil; Rabbits; Rats; Rats, Inbred Strains; Trachea; Urinary Bladder; Urogenital System; Uterus; Vas Deferens | 1988 |
Clinical evaluation of the use-dependent QRS prolongation and the reverse use-dependent QT prolongation of class I and class III antiarrhythmic agents and their value in predicting efficacy.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Piperidines; Potassium Channels; Pyridines; Sodium Channels | 1993 |
Class I antiarrhythmic drugs alter the severity of myocardial stunning by modulating ATP-sensitive K+ channels in guinea pig ventricular muscles.
Topics: Animals; Anti-Arrhythmia Agents; Glyburide; Guinea Pigs; Heart; Heart Ventricles; Imidazoles; Lidocaine; Male; Mexiletine; Myocardial Stunning; Potassium Channels | 1998 |
Mexiletine protects myocardium during acute ischemia by opening sarcolemmal K-ATP channel: studies in closed-chest acute ischemia model in rabbits.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Disease Models, Animal; Electrocardiography; Hemodynamics; KATP Channels; Lidocaine; Mexiletine; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rabbits; Sarcolemma; Sodium Channel Blockers; Stroke Volume; Ventricular Function, Left | 2004 |
Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Topics: Brain; Cell Line; Flecainide; Heart; Humans; Lidocaine; Mexiletine; Muscle Proteins; Muscle, Skeletal; NAV1.1 Voltage-Gated Sodium Channel; NAV1.4 Voltage-Gated Sodium Channel; NAV1.5 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Patch-Clamp Techniques; Sodium Channel Blockers; Sodium Channels | 2010 |