pilsicainide has been researched along with disopyramide in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (15.38) | 18.7374 |
| 1990's | 10 (38.46) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Sen, S; Sinha, N | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Arita, M; Kiyosue, T; Sato, T; Wu, B | 1 |
| Handa, S; Ogawa, S; Okada, Y; Sadanaga, T | 1 |
| Ikeda, N; Kamiya, K | 1 |
| Akaike, N; Inomata, N; Ishihara, T | 1 |
| Aisaka, K; Hattori, Y; Hidaka, T; Ishihara, T; Satoh, F | 1 |
| Hashimoto, Y; Hatta, M; Hattori, Y; Hirotsu, I; Ishihara, T; Kihara, T; Kitakaze, Y; Miyata, T; Nakamura, S; Takahama, K | 1 |
| Hatta, M; Hattori, Y; Hirose, N; Hirotsu, I; Ishihara, T; Kihara, T; Satoh, F | 1 |
| Aisaka, K; Hamasaki, S; Hidaka, T; Inomata, N; Ishihara, T; Morita, M | 1 |
| Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T; Yamahara, Y | 1 |
| Akaishi, M; Handa, S; Iwanaga, S; Ogawa, S; Okada, Y; Sadanaga, T; Tsutsumi, N; Yoshikawa, T | 1 |
| Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Omori, I; Sakai, R; Yamahara, Y | 1 |
| Akaike, N; Inomata, N; Ishihara, T; Ohno, T | 1 |
| Fujiki, A; Inoue, H; Tani, M; Yoshida, S | 1 |
| Baba, S; Funakoshi, M; Ishide, N; Iwabuchi, K; Katoh, H; Keitoku, M; Miura, M; Satoh, S; Shinozaki, T; Shirato, K; Suzuki, S; Takeuchi, M; Watanabe, J | 1 |
| Izumi, T; Kitano, Y; Moriguchi, M; Niwano, S | 1 |
| Hayashi, Y; Hidaka, T; Inomata, N; Inoue, T; Komoriya, K | 1 |
| Aye, NN; Hashimoto, K; Miyamoto, S; Teramatsu, T; Zhu, B | 1 |
| Abe, H; Hiraki, T; Ikeda, H; Imaizumi, T; Kumagai, K; Nakashima, H; Nakashima, Y; Oginosawa, Y; Saku, K | 1 |
| Imai, H; Matoba, Y; Nakagawa, M; Shiraishi, H; Shirayama, T; Yoshida, S | 1 |
| Ando, A; Hirai, M; Inden, Y; Isobe, S; Murohara, T; Nonokawa, M; Okada, M; Suzuki, A; Takada, Y; Tomita, Y | 1 |
| Fujimura, A; Sakamoto, K; Shiga, T; Tsuruoka, S; Wakaumi, M | 1 |
| Aizawa, Y; Chinushi, M; Hirono, T; Komura, S; Sugiura, H | 1 |
| Imai, T; Kajimoto, K; Kasanuki, H; Minami, Y | 1 |
1 review(s) available for pilsicainide and disopyramide
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
4 trial(s) available for pilsicainide and disopyramide
| Article | Year |
|---|---|
Kinetics of frequency-dependent conduction delay by class I antiarrhythmic drugs in human atrium.
Topics: Anti-Arrhythmia Agents; Aprindine; Cardiac Pacing, Artificial; Disopyramide; Electrophysiology; Female; Heart Atria; Heart Conduction System; Humans; Kinetics; Lidocaine; Male; Mexiletine; Middle Aged; Sodium Channels | 1995 |
Electrophysiologic mechanisms of adverse effects of class I antiarrhythmic drugs (cibenzoline, pilsicainide, disopyramide, procainamide) in induction of atrioventricular re-entrant tachycardia.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Disopyramide; Electrophysiology; Female; Heart Conduction System; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Procainamide; Tachycardia, Atrioventricular Nodal Reentry; Wolff-Parkinson-White Syndrome | 1996 |
Single oral administration of pilsicainide versus infusion of disopyramide for termination of paroxysmal atrial fibrillation: a multicenter trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Circadian Rhythm; Disopyramide; Female; Heart Rate; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome | 2000 |
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart Ventricles; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Radionuclide Imaging; Tachycardia, Ventricular; Treatment Outcome; Ventricular Dysfunction, Left | 2004 |
21 other study(ies) available for pilsicainide and disopyramide
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs.
Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Dinitrophenols; Disopyramide; Flecainide; Glyburide; Guinea Pigs; Heart Ventricles; Imidazoles; Lidocaine; Mexiletine; Myocardium; Piperidines; Potassium; Procainamide; Pyridines | 1992 |
[Clinical significance of the use-dependent sodium channel block and reverse use-dependent potassium channel block of class I and class III antiarrhythmic agents and their values to predict drug efficacy].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography, Ambulatory; Electrophysiology; Exercise Test; Humans; Lidocaine; Mexiletine; Middle Aged; Potassium Channels; Sodium Channels | 1992 |
[Estimation of depressant effects of class I antiarrhythmic drugs on intraventricular conduction--rate-dependent effects on QRS duration].
Topics: Anti-Arrhythmia Agents; Aprindine; Depression, Chemical; Disopyramide; Electrocardiography; Flecainide; Heart Conduction System; Heart Rate; Humans; Lidocaine; Mexiletine; Sodium Channels; Ventricular Function | 1992 |
Mechanisms of the anticholinergic effect of SUN 1165 in comparison with flecainide, disopyramide and quinidine in single atrial myocytes isolated from guinea-pig.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Flecainide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardium; Parasympatholytics; Potassium Channels; Quinidine; Receptors, Cholinergic | 1991 |
Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles.
Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Disopyramide; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Ion Channels; Lidocaine; Male; Mexiletine; Papillary Muscles; Piperidines; Sodium | 1988 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Body Temperature; Catalepsy; Cats; Central Nervous System; Chemical Phenomena; Chemistry; Disopyramide; Dogs; Electroencephalography; Female; Hypothermia; Lidocaine; Male; Mexiletine; Mice; Motor Activity; Muscle Relaxation; Pain; Rabbits; Rats; Rats, Inbred Strains; Seizures; Tremor; Vomiting | 1988 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 2nd communication: effect on the peripheral nervous system and peripheral organs.
Topics: Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Capillary Permeability; Chemical Phenomena; Chemistry; Digestive System; Disopyramide; Endocrine Glands; Female; Gastric Mucosa; Gastrointestinal Motility; Guinea Pigs; Ileum; Lidocaine; Male; Mexiletine; Mice; Peripheral Nerves; Pregnancy; Pupil; Rabbits; Rats; Rats, Inbred Strains; Trachea; Urinary Bladder; Urogenital System; Uterus; Vas Deferens | 1988 |
N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate (SUN 1165): a new potent and long-acting antiarrhythmic agent.
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Membrane; Coronary Circulation; Coronary Vessels; Disopyramide; Dogs; Epinephrine; Female; Guinea Pigs; Halothane; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Ouabain; Papillary Muscles | 1985 |
Clinical evaluation of the use-dependent QRS prolongation and the reverse use-dependent QT prolongation of class I and class III antiarrhythmic agents and their value in predicting efficacy.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Piperidines; Potassium Channels; Pyridines; Sodium Channels | 1993 |
Effects of pilsicainide on the atrial fibrillation threshold in guinea pig atria. A comparative study with disopyramide, lidocaine and flecainide.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Electrophysiology; Female; Flecainide; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Male | 1993 |
Antiarrhythmic agents act differently on the activation phase of the ACh-response in guinea-pig atrial myocytes.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Electric Conductivity; Flecainide; Guinea Pigs; Lidocaine; Male; Myocardium; Potassium; Potassium Channels; Propafenone | 1993 |
The rise time of the monophasic action potential--a new index of local use-dependent conductivity by sodium channel blockers in human myocardium.
Topics: Action Potentials; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Disopyramide; Female; Heart; Heart Conduction System; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Sodium Channel Blockers; Sodium Channels | 1997 |
Transient appearance of antegrade conduction via an AV accessory pathway caused by atrial fibrillation in a patient with intermittent Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Procainamide; Wolff-Parkinson-White Syndrome | 2000 |
[Antiarrhythmic effects of pilsicainide hydrochloride and effects on cardiac function and ECG in dogs: comparison with disopyramide].
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Hemodynamics; Infusions, Intravenous; Lidocaine; Ligation | 2000 |
QT-prolonging class I drug, disopyramide, does not aggravate but suppresses adrenaline-induced arrhythmias. Comparison with cibenzoline and pilsicainide.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Disopyramide; Dogs; Drug Interactions; Electrocardiography; Epinephrine; Female; Heart Rate; Imidazoles; Lidocaine; Male | 2000 |
Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Disopyramide; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Treatment Outcome | 2002 |
Pilsicainide in breast milk from a mother: comparison with disopyramide and propafenone.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Disopyramide; Female; Humans; Lidocaine; Milk, Human; Propafenone | 2005 |
Heart rate variability is a useful parameter for evaluation of anticholinergic effect associated with inducibility of atrial fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cholinergic Antagonists; Disopyramide; Dogs; Electrocardiography; Heart Atria; Heart Conduction System; Heart Rate; Lidocaine; Treatment Outcome | 2005 |
Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography, Doppler; Female; Humans; Imidazoles; Lidocaine; Linear Models; Male; Middle Aged; Propranolol; Prospective Studies; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Pressure; Verapamil | 2010 |