piloplex has been researched along with pilocarpine in 5 studies
*Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma. [MeSH]
*Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma. [MeSH]
| Studies (piloplex) | Trials (piloplex) | Recent Studies (post-2010) (piloplex) | Studies (pilocarpine) | Trials (pilocarpine) | Recent Studies (post-2010) (pilocarpine) |
|---|---|---|---|---|---|
| 5 | 3 | 0 | 7,334 | 340 | 1,528 |
| Protein | Taxonomy | piloplex (IC50) | pilocarpine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.0267 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 3.84 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 3.84 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blank, I; Blementhal, M; Gal, A; Mazor, ZW; Ticho, U; Zonis, S | 1 |
| Duzman, E; Klein, HZ; Leon, J; Lugo, M; Shields, MB | 1 |
| Andermann, C; Arne, JL; Bec, P; Mialhe, D; Vende, D | 1 |
| Duzman, E; Quinn, CA; Warman, A; Warman, R | 1 |
| Andermann, G; Cannet, C; de Burlet, G | 1 |
3 trial(s) available for piloplex and pilocarpine
| Article | Year |
|---|---|
A dose-response study of piloplex for duration of action.
Topics: Adult; Dose-Response Relationship, Drug; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Pilocarpine | 1985 |
[Effect on pressure after instillation of a drop of depot-pilocarpine. Clinical results of its medium-term action].
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Tonometry, Ocular | 1983 |
One-month crossover trial comparing the intraocular pressure control of 3.4% Piloplex twice daily with 2.0% pilocarpine four times daily.
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine | 1982 |
2 other study(ies) available for piloplex and pilocarpine
| Article | Year |
|---|---|
Piloplex, a new long-acting pilocarpine polymer salt. A: Long-term study.
Topics: Aged; Circadian Rhythm; Delayed-Action Preparations; Drug Evaluation; Emulsions; Female; Follow-Up Studies; Glaucoma; Humans; In Vitro Techniques; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Polymers; Time Factors | 1979 |
[Comparative study of the antiglaucomatous activity of Glauplex 2 and pilocarpine nitrate on alpha-chymotrypsin-induced experimental glaucoma].
Topics: Animals; Chymotrypsin; Delayed-Action Preparations; Disease Models, Animal; Glaucoma; Ophthalmic Solutions; Pilocarpine; Rabbits; Tonometry, Ocular | 1982 |