pilocarpine has been researched along with thiophenes in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (26.39) | 18.2507 |
| 2000's | 37 (51.39) | 29.6817 |
| 2010's | 14 (19.44) | 24.3611 |
| 2020's | 2 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Brandeis, R; Fisher, A; Gurwitz, D; Haring, R; Heldman, E; Karton, I; Levy, A; Pittel, Z; Sapir, M | 1 |
| Garus, H; Grehn, F; Hennekes, R; Pfeiffer, N | 1 |
| Iwabuchi, Y; Masuhara, T | 1 |
| Lasoń, W; Machelska, H; Przewłocka, B | 1 |
| Fisher, A; Fraser, CM; Gurwitz, D; Haring, R; Heldman, E; Manor, D | 1 |
| Falotico, R; Giardino, EC; Katz, LB; Moore, JB; Salata, JJ | 1 |
| Boddeke, H; Enz, A; Rudin, M; Sauter, A; Shapiro, G | 1 |
| Clineschmidt, CM; Strahlman, ER; Tipping, R; Vogel, R | 1 |
| Rocchi, A; Tingey, D | 1 |
| Masunaga, H; Ogawa, H; Takeshita, Y; Tomizuka, T; Uematsu, Y; Yasuda, H | 1 |
| Izdebska, J | 1 |
| Barisani, T; Baumgartner, I; Biowski, R; Hommer, A; Kaminski, S; Koyuncu, D | 1 |
| Adamsons, I; Snyder, E; Strohmaier, K | 1 |
| Brubaker, R; Dinslage, S; McLaren, J | 1 |
| Adamsons, IA; Boyle, JE; Ostrov, CS; Polis, A | 1 |
| D'Andrea, A; D'Andrea, D; Ferreri, G | 1 |
| Anaya, JM; Talal, N | 1 |
| Gormley, GJ; Hartenbaum, D; Liss, C; Maloney, S; Vaccarelli, L; Wilson, H | 1 |
| Adamsons, I; Gross, R; Pearson, J; Rusk, C; Sverrisson, T | 1 |
| Samuelson, TW; Simmons, ST | 1 |
| Fox, RI; Michelson, P | 1 |
| Anielska, E; Czechowicz-Janicka, K; Dyczkowska, A; Orlewska, E; Tobota, Z | 1 |
| al-Hashimi, I; Taylor, SE | 1 |
| Potocký, M | 1 |
| Atkinson, JC; Baum, BJ | 1 |
| Fisher, A; Fox, RI; Konttinen, Y | 1 |
| Holdiness, MR | 1 |
| Gressnerová, S; Oláh, Z; Veselá, A; Veselovský, J | 2 |
| Muzyka, BC | 1 |
| Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z | 1 |
| Nieuw Amerongen, AV; Veerman, EC | 1 |
| Fong, JC; Hong, SJ; Wang, HZ; Wu, KY | 1 |
| Asari, T; Kojima, M; Kusama, H; Maruyama, K; Omori, Y; Shibata, N | 1 |
| Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzalkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska, A | 1 |
| Cimino, L; Gandolfi, SA; Mora, P; Orzalesi, N; Rossetti, L; Tardini, M | 1 |
| Bruce, SD | 1 |
| Iyer, SA; Neelakantan, A; Sherwood, MB; Vaishnav, HD | 1 |
| Aframian, DJ; Nahlieli, O; Palmon, A | 1 |
| Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzałkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska-Zmijewska, A | 1 |
| Bayer, A; Oeverhaus, U; Skrotzki, FE; Stewart, WC; Weiler, W | 1 |
| Shetty, K | 1 |
| Atkinson, JC; Grisius, M; Massey, W | 1 |
| Al-Hashimi, I | 1 |
| Johnstone, PA; Kahn, ST | 1 |
| Longo, A; Reibaldi, A; Reibaldi, M; Uva, MG | 1 |
| Gause, A | 1 |
| Brennan, MT; Carrozzo, M; Daniels, T; Fox, PC; Fujibayashi, T; Gandera, B; Jonsson, R; Lockhart, PB; Navazesh, M; Rhodus, NL; Schiødt, M; Sollecito, TP; von Bültzingslöwen, I; Wray, D | 1 |
| Gasull, X; Gómez-Cabrero, A; Morales, M; Peral, A; Pintor, J | 1 |
| Carrión, JM; García, MP; Gómez, ME; Huertas, FR | 1 |
| Wick, JY | 1 |
| Akamatsu, T; Azlina, A; Hasegawa, T; Hosoi, K; Karabasil, MR; Li, X; Purwanti, N; Yao, C | 1 |
| Andrade, ED; Bergamaschi, CC; Braga, MA; Groppo, FC; Santos, FA; Tarzia, O | 1 |
| Hosokawa, R; Iida, T; Inagaki, T; Inenaga, K; Ono, K | 1 |
| Adyanthaya, RS; Akpek, EK; Baer, AN; Lindsley, KB; McDonnell, PJ; Swamy, R | 1 |
| Hosokawa, R; Iida, T; Inagaki, T; Inenaga, K; Ono, K; Wakasugi-Sato, N | 1 |
| Chimenos Küstner, E; Jané Salas, E; López-López, J | 1 |
| Campagna, O; Colica, C; Cruciani, F; De Vico, U; Gharbiya, M | 1 |
| Agarwal, P; Agarwal, R; Ismail, NM; Kannan Kutty, M; Kapitonova, MY; Razali, N; Salmah Bakar, N; Smirnov, A | 1 |
| Kawakami, A; Nakamura, H; Nakamura, T; Sato, S; Sumi, M; Takagi, Y | 1 |
| Asbell, PA; Kuklinski, E | 1 |
| Barbe, AG | 1 |
| Forbes, B; Garcia, CMA; Malallah, OS; Proctor, GB; Royall, PG | 1 |
| Cherubini, K; Figueiredo, MAZ; Medella-Junior, FAC; Salum, FG | 1 |
| Bello, TO; Ogunleye, T; Olawoye, OO; Sarimiye, TF | 1 |
| B E, S; Badam, RK; Boringi, M; Garlapati, K; Kammari, A; Soni, P | 1 |
| Chen, CH; Chou, YC; Huang, WY; Ju, UH; Kao, CH; Lin, CL; Lin, CS; Lin, KT; Lin, TY; Liu, FC; Shen, CH; Yang, TY | 1 |
| Cimmino, J; Farag, AM; Holliday, C; Papas, A; Roomian, T | 1 |
| He, J; Liu, S; Shen, K; Wei, Y; Wu, K; Yang, H; Yang, X; Yue, J; Zhang, C | 1 |
| Graue-Hernandez, EO; Kahuam-López, N; Navas, A; Pérez Vázquez, AK; Ramirez-Miranda, A; Serrano-Robles, JG | 1 |
18 review(s) available for pilocarpine and thiophenes
| Article | Year |
|---|---|
[Trusopt--a new form of drug for treating glaucoma].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Therapy, Combination; Glaucoma; Intraocular Pressure; Pilocarpine; Sulfonamides; Thiophenes | 1997 |
Sjögren's syndrome comes of age.
Topics: Apoptosis; Humans; Lymphocytosis; Muscarinic Agonists; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Salivary Glands; Sjogren's Syndrome; Thiophenes | 1999 |
Approaches to the treatment of Sjögren's syndrome.
Topics: Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes | 2000 |
Use of muscarinic agonists in the treatment of Sjögren's syndrome.
Topics: Humans; Muscarinic Agonists; Neuroimmunomodulation; Neurosecretory Systems; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Sjogren's Syndrome; Thiophenes | 2001 |
Contact dermatitis to topical drugs for glaucoma.
Topics: Dermatitis, Allergic Contact; Epinephrine; Glaucoma; Humans; Ophthalmic Solutions; Pilocarpine; Sulfonamides; Thiophenes; Timolol | 2001 |
Current therapies for xerostomia and salivary gland hypofunction associated with cancer therapies.
Topics: Acupuncture Therapy; Antineoplastic Agents; Chewing Gum; Diet; Flavoring Agents; Humans; Muscarinic Agonists; Neoplasms; Oral Hygiene; Palliative Care; Parasympathomimetics; Pilocarpine; Quinuclidines; Radiotherapy; Saliva; Salivary Glands; Thiophenes; Xerostomia | 2003 |
Radiation-induced xerostomia: how dry is your patient?
Topics: Acupuncture Therapy; Head and Neck Neoplasms; Humans; Muscarinic Agonists; Nurse's Role; Nursing Assessment; Oncology Nursing; Oral Hygiene; Pilocarpine; Quality of Life; Quinuclidines; Radiotherapy; Radiotherapy Dosage; Salivation; Thiophenes; Xerostomia | 2004 |
Salivary hypofunction and xerostomia: diagnosis and treatment.
Topics: Aged; Aged, 80 and over; Cariostatic Agents; Fluorides; Humans; Pilocarpine; Polypharmacy; Quinuclidines; Radiotherapy; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia | 2005 |
Xerostomia secondary to Sjögren's syndrome in the elderly: recognition and management.
Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes; Xerostomia | 2005 |
Management of xerostomia related to radiotherapy for head and neck cancer.
Topics: Acupuncture Therapy; Amifostine; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Muscarinic Agonists; Palliative Care; Pilocarpine; Quinuclidines; Radiation-Protective Agents; Radiotherapy; Submandibular Gland; Thiophenes; Xerostomia | 2005 |
Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antiviral Agents; Diabetes Complications; HIV Infections; Humans; Interferon-alpha; Muscarinic Agonists; Pilocarpine; Quinuclidines; Rituximab; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia | 2007 |
Xerostomia: causes and treatment.
Topics: Autoimmune Diseases; Bone Marrow Transplantation; Drug-Related Side Effects and Adverse Reactions; Humans; Pilocarpine; Quinuclidines; Saliva; Thiophenes; Xerostomia | 2007 |
Treatment of Sjögren's syndrome-associated dry eye an evidence-based review.
Topics: Administration, Oral; Administration, Topical; Anti-Inflammatory Agents; Dry Eye Syndromes; Evidence-Based Medicine; Humans; Hydroxychloroquine; Immunosuppressive Agents; Lubricants; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes | 2011 |
[Prognosis and treatment of dry mouth. Systematic review].
Topics: Cholinergic Antagonists; Clinical Trials as Topic; Dental Caries; Disease Susceptibility; Double-Blind Method; Fluid Therapy; Humans; Meta-Analysis as Topic; Mouthwashes; Observational Studies as Topic; Pilocarpine; Prognosis; Quinuclidines; Radiation Injuries; Radiotherapy; Saliva, Artificial; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia | 2014 |
Sjogren's syndrome from the perspective of ophthalmology.
Topics: Administration, Ophthalmic; Cyclosporine; Dry Eye Syndromes; Fatty Acids, Omega-3; Glucocorticoids; Humans; Immunosuppressive Agents; Lubricant Eye Drops; Muscarinic Agonists; Ophthalmology; Phenylalanine; Pilocarpine; Punctal Plugs; Quinuclidines; Sjogren's Syndrome; Sulfones; Thiophenes | 2017 |
Buccal drug delivery technologies for patient-centred treatment of radiation-induced xerostomia (dry mouth).
Topics: Drug Delivery Systems; Head and Neck Neoplasms; Humans; Mouth Mucosa; Muscarinic Agonists; Pilocarpine; Quinuclidines; Radiation Injuries; Saliva; Thiophenes; Time Factors; Xerostomia | 2018 |
Salivary hypofunction: An update on therapeutic strategies.
Topics: Acupuncture Therapy; Bethanechol; Chewing Gum; Humans; Hyperbaric Oxygenation; Muscarinic Agonists; Pilocarpine; Quinuclidines; Thiophenes; Xerostomia | 2018 |
Meta-analysis on pharmacological therapies in the management of xerostomia in patients with Sjogren's syndrome.
Topics: Female; Humans; Interferon-alpha; Male; Pilocarpine; Quinuclidines; Saliva; Sjogren's Syndrome; Thiophenes | 2019 |
15 trial(s) available for pilocarpine and thiophenes
| Article | Year |
|---|---|
[Decrease in intraocular pressure following administration of the local carbonic anhydrase inhibitor (MK-927)--comparison of the effect with pilocarpine].
Topics: Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes | 1990 |
The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pilot Projects; Safety; Sulfonamides; Thiophenes; Timolol | 1996 |
Economic evaluation of dorzolamide vs. pilocarpine for primary open-angle glaucoma.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Costs and Cost Analysis; Glaucoma, Open-Angle; Humans; Models, Economic; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Sulfonamides; Thiophenes | 1997 |
A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Quality of Life; Sulfonamides; Thiophenes; Timolol; Visual Fields | 1998 |
Two-year safety study of dorzolamide as monotherapy and with timolol and pilocarpine. Dorzolamide Safety Study Group.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
Clinical use of a topical carbonic anhydrase inhibitor in patients affected by chronic simple glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Comparison of dorzolamide and pilocarpine as adjunctive therapy in patients with open-angle glaucoma and ocular hypertension.
Topics: Adjuvants, Pharmaceutic; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Parasympathomimetics; Patient Dropouts; Pilocarpine; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 1999 |
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1999 |
Comparison of brimonidine with latanoprost in the adjunctive treatment of glaucoma. ALPHAGAN/XALATAN Study Group.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2000 |
Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Replacing maximum-tolerated medications with latanoprost versus adding latanoprost to maximum-tolerated medications: a two-center randomized prospective trial.
Topics: Adrenergic beta-Antagonists; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Retreatment; Single-Blind Method; Sulfonamides; Thiophenes | 2003 |
[Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients].
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Two-year follow-up of latanoprost 0.005% monotherapy after changing from previous glaucoma therapies.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2004 |
The effect of timolol-dorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Ciliary Arteries; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Artery; Pilocarpine; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2006 |
Comparison of the effects of pilocarpine and cevimeline on salivary flow.
Topics: Administration, Oral; Adult; Cross-Over Studies; Humans; Male; Muscarinic Agonists; Physical Stimulation; Pilocarpine; Quinuclidines; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Saliva; Salivary Glands; Secretory Rate; Single-Blind Method; Thiophenes; Time Factors; Young Adult | 2009 |
39 other study(ies) available for pilocarpine and thiophenes
| Article | Year |
|---|---|
(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Binding, Competitive; Cognition Disorders; Copper; Disease Models, Animal; Male; Memory; Mice; Motor Activity; Parasympathomimetics; Pilocarpine; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Muscarinic; Thiophenes | 1991 |
Sialogogic activities of SNI-2011 compared with those of pilocarpine and McN-A-343 in rat salivary glands: identification of a potential therapeutic agent for treatment of Sjörgen's syndrome.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adrenergic Antagonists; Animals; Cholinergic Antagonists; Male; Pilocarpine; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Salivary Glands; Salivation; Sjogren's Syndrome; Thiophenes | 1994 |
Kappa opioid receptor agonists inhibit the pilocarpine-induced seizures and toxicity in the mouse.
Topics: Analgesics; Animals; Benzeneacetamides; Brain; Injections, Intraperitoneal; Mice; Naltrexone; Pilocarpine; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Seizures; Thiophenes | 1994 |
Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Calcium; Carbachol; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Hydrolysis; Phosphatidylinositols; Pilocarpine; Protein Binding; Quinuclidines; Receptors, Cholinergic; Signal Transduction; Thiophenes; Transfection | 1994 |
RWJ 26629, a new potassium channel opener and vascular smooth muscle relaxant: a potential antihypertensive and antianginal agent.
Topics: Angina Pectoris; Animals; Antihypertensive Agents; Benzopyrans; Bronchoconstriction; Calcium Channel Blockers; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Ferrets; Gastrointestinal Motility; Guinea Pigs; Heart Atria; Macaca mulatta; Male; Mice; Mice, Inbred Strains; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrendipine; Papillary Muscles; Pilocarpine; Potassium Channels; Pyrans; Pyrroles; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rubidium; Rubidium Radioisotopes; Thiophenes; Vasodilator Agents | 1993 |
SDZ ENS 163 a novel pilocarpine like drug: pharmacological in vitro and in vivo profile.
Topics: Acetylcholine; Animals; Brain; CHO Cells; Cricetinae; Ganglia, Sympathetic; Guinea Pigs; Ileum; Imidazoles; Male; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Pilocarpine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Thiophenes | 1993 |
Long-lasting salivation induced by a novel muscarinic receptor agonist SNI-2011 in rats and dogs.
Topics: Animals; Dogs; Female; Male; Muscarinic Agonists; Pilocarpine; Quinuclidines; Rats; Rats, Wistar; Salivation; Secretory Rate; Thiophenes; Time Factors | 1997 |
Influence of dorzolamide on corneal thickness, endothelial cell count and corneal sensibility.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Cell Count; Chronic Disease; Cornea; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Sensation; Sulfonamides; Thiophenes; Timolol | 1998 |
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs.
Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Cevimeline (Evoxac) for dry mouth.
Topics: Acetylcholine; Clinical Trials as Topic; Contraindications; Humans; Intestinal Absorption; Muscarinic Agonists; Nausea; Pilocarpine; Quinuclidines; Thiophenes; Xerostomia | 2000 |
[Analysis of glaucoma therapy costs in Poland. I--population of the Mazovian District].
Topics: Adult; Aged; Aged, 80 and over; Costs and Cost Analysis; Disease Progression; Female; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Office Visits; Pilocarpine; Poland; Sulfonamides; Thiophenes; Timolol | 2000 |
A new medication for treatment of dry mouth in Sjögren's syndrome.
Topics: Contraindications; Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Salivary Glands; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia | 2001 |
[Additive effects of topical carbonic anhydrase inhibitors].
Topics: Aged; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Salivary enhancement: current status and future therapies.
Topics: Animals; Aquaporin 1; Aquaporins; Blood Group Antigens; Cholinergic Agents; Cranial Irradiation; Dental Caries; Genetic Therapy; Humans; Parasympathomimetics; Pilocarpine; Quinuclidines; Salivary Glands; Sjogren's Syndrome; Thiophenes; Xerostomia | 2001 |
[The pH reaction in aqueous humor to antiglaucoma agents of various concentrations and pH levels].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aqueous Humor; Female; Glaucoma; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Latanoprost; Male; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Assessing salivary gland hypofunction--Part two.
Topics: Anti-Infective Agents, Local; Candidiasis, Oral; Dental Caries; Humans; Maltose; Mastication; Muscarinic Agonists; Pilocarpine; Quinuclidines; Saliva; Thiophenes; Xerostomia | 2002 |
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases | 2003 |
Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells.
Topics: Animals; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Calcium; Carteolol; Cell Death; Dose-Response Relationship, Drug; Epinephrine; Glaucoma; Glutamic Acid; Latanoprost; Mice; Neuroblastoma; Neurons; Neuroprotective Agents; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol; Tumor Cells, Cultured | 2003 |
The free amino acids and the aqueous humor pH after antiglaucomatics in vitro.
Topics: Aged; Aged, 80 and over; Amino Acids; Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Latanoprost; Male; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2003 |
Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation.
Topics: Animals; Antipsychotic Agents; Body Temperature; Cardiovascular System; Central Nervous System; Chlorpromazine; Dose-Response Relationship, Drug; Male; Muscarinic Agonists; Pilocarpine; Quinuclidines; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Respiratory System; Salivary Proteins and Peptides; Salivation; Submandibular Gland; Thiophenes; Xerostomia | 2003 |
Is addition of a third or fourth antiglaucoma medication effective?
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Prostaglandins; Retrospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
[Future therapy strategies for salivary gland impairment].
Topics: Amifostine; Cranial Irradiation; Head and Neck Neoplasms; Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Radiation Injuries; Radiation-Protective Agents; Regeneration; Saliva; Salivary Glands; Thiophenes | 2004 |
Dentistry. Implications and management of xerostomia in the HIV patient.
Topics: Antiretroviral Therapy, Highly Active; Cholinergic Agents; HIV Infections; HIV Protease Inhibitors; Humans; Pilocarpine; Quinuclidines; Reverse Transcriptase Inhibitors; Thiophenes; Xerostomia | 2005 |
New approaches to preventing xerostomia.
Topics: Amifostine; Cytoprotection; Humans; Muscarinic Agonists; Neoplasms; Pilocarpine; Quinuclidines; Radiation Injuries; Radiation-Protective Agents; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Salivary Glands; Thiophenes; Xerostomia | 2006 |
[Revision of the recommendations of the Commission on Pharmacotherapy of the German Society for Rheumatology. Recommendations for supportive therapy for Sjögren's syndrome].
Topics: Bromhexine; Cyclosporine; Dry Eye Syndromes; Electric Stimulation Therapy; Expectorants; Humans; Muscarinic Antagonists; Ophthalmic Solutions; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes; Xerostomia | 2007 |
Hypotensive effect of profilin on rabbit intraocular pressure.
Topics: Animals; Antihypertensive Agents; Intraocular Pressure; Latanoprost; Pilocarpine; Profilins; Prostaglandins F, Synthetic; Protein Structure, Tertiary; Rabbits; Recombinant Fusion Proteins; Sulfonamides; Thiophenes | 2007 |
[Acute closed-angle glaucoma after gynecological surgery under general anesthesia].
Topics: Acetazolamide; Acute Disease; Anesthesia, General; Atropine; Combined Modality Therapy; Corneal Edema; Dexamethasone; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Humans; Laser Therapy; Mannitol; Middle Aged; Mydriasis; Pilocarpine; Postoperative Complications; Sulfonamides; Thiophenes; Timolol; Vomiting | 2007 |
Degradation of submandibular gland AQP5 by parasympathetic denervation of chorda tympani and its recovery by cevimeline, an M3 muscarinic receptor agonist.
Topics: Animals; Aquaporin 1; Aquaporin 5; Chorda Tympani Nerve; Gene Expression Regulation; Lysosomes; Male; Muscarinic Agonists; Parasympathectomy; Pilocarpine; Quinuclidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Submandibular Gland; Sympathectomy; Thiophenes; Time Factors | 2008 |
Effects of pilocarpine and cevimeline on Ca2+ mobilization in rat parotid acini and ducts.
Topics: Animals; Calcium; Calcium Signaling; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Pilocarpine; Piperidines; Quinuclidines; Rats; Receptors, Muscarinic; Thiophenes | 2009 |
Distinct effects of cevimeline and pilocarpine on salivary mechanisms, cardiovascular response and thirst sensation in rats.
Topics: Analysis of Variance; Animals; Cardiovascular System; Drinking; Muscarinic Agonists; Parotid Gland; Pilocarpine; Quinuclidines; Rats; Rats, Wistar; Salivation; Sensitivity and Specificity; Subfornical Organ; Thiophenes; Thirst | 2012 |
Urrets- Zavalia Syndrome after glaucoma filtration device implantation.
Topics: Acetazolamide; Aged; Brimonidine Tartrate; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Drug Therapy, Combination; Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Hypertension; Miotics; Mydriasis; Ocular Hypertension; Pilocarpine; Prostaglandins F; Quinoxalines; Sulfonamides; Syndrome; Thiophenes; Timolol | 2013 |
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol | 2015 |
Salivary gland ultrasonography as a primary imaging tool for predicting efficacy of xerostomia treatment in patients with Sjögren's syndrome.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glucocorticoids; Humans; Male; Middle Aged; Muscarinic Agonists; Parasympathomimetics; Pilocarpine; Prednisolone; Prognosis; Quinuclidines; Retrospective Studies; Salivary Glands; Severity of Illness Index; Sjogren's Syndrome; Therapeutic Irrigation; Thiophenes; Treatment Outcome; Ultrasonography; Xerostomia | 2016 |
Long-term Use of the Sialogogue Medications Pilocarpine and Cevimeline Can Reduce Xerostomia Symptoms and Increase Salivary Flow in Head and Neck Cancer Survivors After Radiotherapy.
Topics: Head and Neck Neoplasms; Humans; Pilocarpine; Quinuclidines; Survivors; Thiophenes; Xerostomia | 2017 |
Acute angle closure following hemodialysis in a 34-year-old Nigerian female.
Topics: Adult; Drug Combinations; Female; Glaucoma; Glaucoma, Angle-Closure; Glomerulonephritis; Gonioscopy; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Renal Dialysis; Renal Insufficiency, Chronic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2018 |
Risk of Parkinson disease in Sjögren syndrome administered ineffective immunosuppressant therapies: A nationwide population-based study.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Comorbidity; Female; Humans; Hydroxychloroquine; Immunosuppression Therapy; Incidence; Male; Methylprednisolone; Middle Aged; Muscarinic Agonists; National Health Programs; Parkinson Disease; Pilocarpine; Quinuclidines; Retrospective Studies; Risk Factors; Sjogren's Syndrome; Taiwan; Thiophenes | 2019 |
Comparing the effectiveness and adverse effects of pilocarpine and cevimeline in patients with hyposalivation.
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Middle Aged; Muscarinic Agonists; Pilocarpine; Quinuclidines; Retrospective Studies; Thiophenes; Time Factors; Xerostomia | 2019 |
Decreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model.
Topics: Adolescent; Adult; Animals; Anti-Inflammatory Agents; Convulsants; Cytokines; Encephalitis; Epilepsy, Temporal Lobe; Gene Expression Regulation; Gliosis; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nuclear Receptor Subfamily 1, Group D, Member 1; Pilocarpine; Pyrrolidines; Status Epilepticus; Temporal Lobe; Thiophenes; Young Adult | 2020 |
Safety and efficacy of pilocarpine, cevimeline, and diquafosol compared to artificial tears for the treatment of dry eye: protocol for a systematic review.
Topics: Dry Eye Syndromes; Humans; Lubricant Eye Drops; Meta-Analysis as Topic; Pilocarpine; Polyphosphates; Quinuclidines; Secretagogues; Systematic Reviews as Topic; Thiophenes; Uracil Nucleotides | 2022 |