pilocarpine has been researched along with sirolimus in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 14 (82.35) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Baum, BJ; Voutetakis, A; Wang, J; Zheng, C | 1 |
| Buckmaster, PS; Ingram, EA; Wen, X | 1 |
| Cao, Z; Gruenthal, M; Huang, X; Huang, Y; Lin, Y; McMahon, J; Wu, J; Yang, J; Zhang, H | 1 |
| Buckmaster, PS; Wen, X | 1 |
| Buckmaster, PS; Lew, FH | 1 |
| Huang, X; Huang, Y; McMahon, J | 1 |
| Huang, X; Huang, Y; McMahon, J; Shin, D; Yang, J | 1 |
| Anderson, AE; Brewster, AL; Lee, WL; Lugo, JN; Patil, VV; Qian, Y; Vanegas, F | 1 |
| Buckmaster, PS; Haney, MM; Heng, K | 1 |
| Chen, T; Shi, Q; Weng, L; Xie, Y; Zeng, L; Zhang, H; Zhang, Y | 1 |
| Buckmaster, PS; Thind, K; Yamawaki, R | 1 |
| Danzer, SC; Garcia-Cairasco, N; Hester, MS; Hosford, BE; LaSarge, CL; Liska, JP; Rolle, IJ; Santos, VR; Singh, SP | 1 |
| Arafat, A; Gan, N; Peng, J; Xiao, Z; Yin, F | 1 |
| Dong, J; Liu, L; Wang, Q; Zeng, L; Zhang, B; Zhang, Y; Zhu, F | 1 |
| Chen, Z; Fang, Q; He, L; Liu, L; Liu, Z; Xu, Y; Zeng, C | 1 |
1 review(s) available for pilocarpine and sirolimus
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
16 other study(ies) available for pilocarpine and sirolimus
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Rapamycin control of exocrine protein levels in saliva after adenoviral vector-mediated gene transfer.
Topics: Adenoviridae; Animals; Anti-Bacterial Agents; Cell Line; Gene Expression; Genetic Therapy; Genetic Vectors; Human Growth Hormone; Humans; Oral Ulcer; Pilocarpine; Rats; Saliva; Sirolimus; Transduction, Genetic; Transgenes | 2004 |
Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Atropine Derivatives; Axons; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Immunohistochemistry; Infusions, Parenteral; Injections, Intraperitoneal; Male; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neural Inhibition; Neurons; Parasympatholytics; Pilocarpine; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Staining and Labeling; Status Epilepticus; Time Factors; TOR Serine-Threonine Kinases | 2009 |
Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy.
Topics: Animals; Convulsants; Disease Models, Animal; Epilepsy; Hippocampus; Male; Mossy Fibers, Hippocampal; Neuronal Plasticity; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2010 |
Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy.
Topics: Animals; Axons; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Green Fluorescent Proteins; Interneurons; Male; Mice; Pilocarpine; Sirolimus; Somatostatin; Status Epilepticus; Synapses | 2011 |
Is there a critical period for mossy fiber sprouting in a mouse model of temporal lobe epilepsy?
Topics: Animals; Critical Period, Psychological; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Immunosuppressive Agents; Mice; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neurons; Pilocarpine; Sirolimus; Time Factors | 2011 |
Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy.
Topics: Aggression; Animals; Behavior, Animal; Disease Models, Animal; Immunosuppressive Agents; Physical Stimulation; Pilocarpine; Rats; Rats, Sprague-Dawley; Sirolimus; Status Epilepticus; Touch | 2012 |
Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Convulsants; Disease Susceptibility; Down-Regulation; Immunohistochemistry; K Cl- Cotransporters; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Sirolimus; Symporters; TOR Serine-Threonine Kinases | 2012 |
Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage.
Topics: Animals; Dendrites; Dendritic Spines; Disease Models, Animal; Electroencephalography; Gliosis; Hippocampus; Ion Channels; Male; Maze Learning; Mechanistic Target of Rapamycin Complex 1; Memory Disorders; Microglia; Multiprotein Complexes; Neurons; Phosphorylation; Pilocarpine; Rats; Ribosomal Protein S6 Kinases; Sirolimus; Status Epilepticus; TOR Serine-Threonine Kinases | 2013 |
High-dose rapamycin blocks mossy fiber sprouting but not seizures in a mouse model of temporal lobe epilepsy.
Topics: Animals; Axons; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Male; Mice; Mossy Fibers, Hippocampal; Neurons; Pilocarpine; Sirolimus | 2013 |
[Rapamycin improves learning and memory ability in ICR mice with pilocarpine-induced temporal lobe epilepsy].
Topics: Animals; Cell Death; Disease Models, Animal; Epilepsy; Learning; Memory; Mice; Mice, Inbred ICR; Neurons; Pilocarpine; Sirolimus | 2013 |
Blockade of excitatory synaptogenesis with proximal dendrites of dentate granule cells following rapamycin treatment in a mouse model of temporal lobe epilepsy.
Topics: Animals; Dendrites; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Male; Mice; Microscopy, Electron; Neuroprotective Agents; Pilocarpine; Sirolimus; Status Epilepticus; Synapses | 2015 |
Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain.
Topics: Animals; Carrier Proteins; Cation Transport Proteins; Cell Movement; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Immunosuppressive Agents; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mossy Fibers, Hippocampal; Neurogenesis; Neurons; Pilocarpine; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Status Epilepticus; Weight Gain; Zinc Finger Protein GLI1 | 2016 |
Interleukin-1β Plays a Pivotal Role via the PI3K/Akt/mTOR Signaling Pathway in the Chronicity of Mesial Temporal Lobe Epilepsy.
Topics: Animals; Anticonvulsants; Cells, Cultured; Child; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Female; Gene Expression Regulation; Hippocampus; Humans; Interleukin-1beta; Male; Muscarinic Agonists; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2016 |
[Efficacy of brain-targeted rapamycin for treatment of epilepsy in rats].
Topics: Animals; Brain; Disease Models, Animal; Epilepsy; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Treatment Outcome | 2018 |
Dynorphin/KOR inhibits neuronal autophagy by activating mTOR signaling pathway to prevent acute seizure epilepsy.
Topics: Animals; Anticonvulsants; Apoptosis; Autophagy; Biotin; Dynorphins; Epilepsy; Green Fluorescent Proteins; Mammals; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA, Messenger; Seizures; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2022 |