pilocarpine has been researched along with piperidines in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (19.64) | 18.7374 |
| 1990's | 14 (25.00) | 18.2507 |
| 2000's | 13 (23.21) | 29.6817 |
| 2010's | 17 (30.36) | 24.3611 |
| 2020's | 1 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Finkel, MP; Giles, RE; Williams, JC | 1 |
| Hofmann, HP; Kreiskott, H | 1 |
| Gianutsos, G; Lal, H | 1 |
| Iwabuchi, Y; Masuhara, T | 1 |
| Gabelt, BT; Kaufman, PL | 1 |
| Boddeke, HW | 1 |
| Harbon, S; Leiber, D; Marc, S | 1 |
| Roger, T; Ruckebusch, Y | 1 |
| Esplin, DW; Zablocka, B | 1 |
| Esplin, DW; Ferguson, RK; Zablocka-Esplin, B | 1 |
| Mashkovsky, MD; Yakhontov, LN | 1 |
| Brugmans, J; Demoen, P; Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Schellekens, KH; Van Nueten, JM; Van Wijngaarden, I | 1 |
| Kimura, K; Nagasawa, H; Nomura, A; Ohata, K; Shimomura, S | 1 |
| Hackmiller, RC; Jumblatt, JE | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Francis, NJ; Grant, MP; Landis, SC | 1 |
| Hamstra, JJ; Roffel, AF; Santing, RE; ten Berge, RE; Zaagsma, J | 1 |
| Eguíbar, JR; Holmgren, B; Santos, A; Urbá-Holmgren, R | 1 |
| Deirmengiant, C; Maslanski, JA; Patelt, J; Powelt, R | 1 |
| Eglen, RM; Harris, GC | 1 |
| De Neef, P; Domenach, V; Vandermeers, A; Vandermeers-Piret, MC; Waelbroeck, M | 1 |
| Belmonte, KE; Costello, RW; Fryer, AD; Jacoby, DB | 1 |
| Lu, Y; Shi, H; Wang, H; Wang, Z; Yang, B | 1 |
| Elwood, T; Fryer, AD; Jacoby, DB; Yost, BL | 1 |
| Bourreau, JP; Huang, Y; Shen, S | 1 |
| Choppin, A; Eglen, RM | 1 |
| Egashira, N; Fujii, M; Fujiwara, M; Hirosawa, N; Iwasaki, K; Matsumoto, Y; Mishima, K | 1 |
| STROMBLAD, BC | 2 |
| Jones, RS; Woodhall, GL; Yang, J | 1 |
| Lü, YJ; Yang, BF; Yue, P | 1 |
| Auberson, YP; Carmignoto, G; Coulter, DA; Ding, S; Fellin, T; Haydon, PG; Lee, SY; Meaney, DF; Zhu, Y | 1 |
| Borella, TL; Colombari, DS; De Luca, LA; Menani, JV | 1 |
| Kamei, C; Masuoka, T | 1 |
| Asari, T; Kusama, H; Maruyama, K | 1 |
| Chen, LP; Chen, W; Han, HM; Li, DL; Liu, Y; Pan, ZY; Qi, HP; Sun, HL; Wang, LY; Xie, J; Zhao, WM | 1 |
| Hosokawa, R; Iida, T; Inagaki, T; Inenaga, K; Ono, K | 1 |
| Borda, E; Passafaro, D; Reina, S; Sterin-Borda, L | 1 |
| Nayak, S; Pal, A; Sahu, PK; Swain, T | 1 |
| Abramochkin, DV; Nikolsky, EE; Nurullin, LF; Sukhova, GS; Tapilina, SV | 1 |
| Aerssens, J; Aourz, N; Bortolotto, ZA; Clinckers, R; Collingridge, GL; Coppens, J; Loyens, E; Michotte, Y; Moechars, D; Portelli, J; Schallier, A; Smolders, I; Thielemans, L; Ver Donck, L; Vermoesen, K | 1 |
| Di Maio, R; Greenamyre, JT; Hu, X; Mastroberardino, PG; Montero, LM | 1 |
| Brito, GA; Cavalheiro, EA; da Costa, MA; da Cruz, GM; da Graça Naffah-Mazzacoratti, M; de Andrade, GM; de Barros Viana, GS; Felipe, CF; Leal, LK; Menezes, ML; Scorza, FA; Tavares, AF | 1 |
| Abramochkin, DV; Sukhova, GS; Tapilina, SV | 1 |
| Mukae, T; Uchida, H; Ueda, H | 1 |
| Abramochkin, DV; Tapilina, SV | 1 |
| Carletti, F; Ferraro, G; Gambino, G; Rizzo, V; Sardo, P | 1 |
| Proddutur, A; Santhakumar, V; Swietek, B; Yu, J | 1 |
| Guli, X; Kirschstein, T; Köhling, R; Tokay, T | 1 |
| Choi, BY; Choi, HC; Hong, DK; Jeong, JH; Kho, AR; Lee, SH; Lee, SY; Song, HK; Suh, SW | 1 |
| Abbasova, K; Kubová, H; Mareš, P | 1 |
| Cheng, DF; Ding, J; Shi, HC; Si, Z; Wang, X; Wu, XQ; Zhao, YN | 1 |
| Chen, Q; Ding, J; Hammock, BD; Li, D; Liu, J; Peng, W; Shen, Y; Wang, X; Yang, J | 1 |
| Hou, Z; Liang, C; Liu, S; Wang, L; Wu, K; Yang, H; Yue, J; Zhang, C | 1 |
| Murakami, M; Narita, T; Qi, B; Sugiya, H | 1 |
2 review(s) available for pilocarpine and piperidines
| Article | Year |
|---|---|
Relationships between the chemical structure and pharmacological activity in a series of synthetic quinuclidine derivatives.
Topics: Animals; Benactyzine; Carbamates; Cats; Chemical Phenomena; Chemistry; Esters; Ganglionic Blockers; Iodides; Mice; Parasympatholytics; Pilocarpine; Piperidines; Prochlorperazine; Pupil; Quinuclidines; Rabbits; Rats; Salicylates; Tubocurarine | 1969 |
[Advances in the study of cardiac M3 receptor as a novel target of antiarrhythmic drugs].
Topics: Animals; Delayed Rectifier Potassium Channels; Humans; Membrane Potentials; Myocardial Ischemia; Pilocarpine; Piperidines; Receptor, Muscarinic M3; Signal Transduction | 2006 |
54 other study(ies) available for pilocarpine and piperidines
| Article | Year |
|---|---|
Pharmacologic studies on W10,294A, a new bronchodilator.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Airway Resistance; Animals; Barium; Bronchial Spasm; Bronchodilator Agents; Coumarins; Dogs; Female; Guinea Pigs; Heart Rate; Histamine H1 Antagonists; In Vitro Techniques; Lung; Lung Compliance; Male; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Pilocarpine; Piperidines | 1977 |
[Central and peripheral interactions of the antiparkinson agent biperiden and the antihistaminic bamipin on the rat excited by pilocarpine].
Topics: Animals; Behavior, Animal; Benzylamines; Biperiden; Drug Interactions; Histamine H1 Antagonists; Male; Nervous System; Pilocarpine; Piperidines; Rats | 1978 |
Alteration in the action of cholinergic and anti cholinergic drugs after chronic haloperidol: indirect evidence for cholinergic hyposensitivity.
Topics: Acetylcholine; Amphetamines; Animals; Dexetimide; Dopamine; Haloperidol; Male; Motor Activity; Pentobarbital; Pilocarpine; Piperidines; Rats; Receptors, Cholinergic; Time Factors | 1976 |
Effects of cholinergic and adrenergic agonists on the secretion of fluid and protein by submandibular glands of the hamster and the rat.
Topics: Animals; Cricetinae; Isoproterenol; Male; Mesocricetus; Metoprolol; Parasympathomimetics; Phenylephrine; Pilocarpine; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Saliva; Salivary Proteins and Peptides; Submandibular Gland; Sympathomimetics | 1992 |
Inhibition of outflow facility and accommodative and miotic responses to pilocarpine in rhesus monkeys by muscarinic receptor subtype antagonists.
Topics: Accommodation, Ocular; Animals; Aqueous Humor; Female; Intraocular Pressure; Macaca mulatta; Male; Miosis; Muscarinic Antagonists; Parasympatholytics; Phenylephrine; Pilocarpine; Piperidines; Pirenzepine; Pupil | 1992 |
Different effects of muscarinic agonists in rat superior cervical ganglion and hippocampal slices.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arecoline; Ganglia, Sympathetic; Hippocampus; In Vitro Techniques; Male; Oxotremorine; Parasympathomimetics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains | 1991 |
Pharmacological evidence for distinct muscarinic receptor subtypes coupled to the inhibition of adenylate cyclase and to the increased generation of inositol phosphates in the guinea pig myometrium.
Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myometrium; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Type C Phospholipases; Uterine Contraction | 1990 |
Prokinetic effects of cisapride, naloxone and parasympathetic stimulation at the equine ileo-caeco-colonic junction.
Topics: Animals; Carbachol; Cecum; Cisapride; Colon; Gastrointestinal Motility; Horses; Ileum; Injections, Intravenous; Metoclopramide; Naloxone; Parasympathomimetics; Pilocarpine; Piperidines | 1988 |
Pharmacological evidence for cholinergic processes in various central synapses.
Topics: Animals; Cats; Electrophysiology; Heterocyclic Compounds; Muscle Spindles; Neuromuscular Junction; Paralysis; Parasympathomimetics; Physostigmine; Pilocarpine; Piperidines; Seizures; Strychnine; Synapses; Tachyphylaxis | 1966 |
Peripheral cholinergic blockade by drugs that block postsynaptic central inhibition.
Topics: Aldehydes; Animals; Cats; Electric Stimulation; Heterocyclic Compounds; Neural Conduction; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Nicotinic Acids; Physostigmine; Pilocarpine; Piperidines; Strychnine; Synaptic Transmission; Thebaine | 1970 |
Benzetimide and its optical isomers.
Topics: Animals; Atropine; Benzyl Compounds; Carbon Isotopes; Diarrhea; Dogs; Female; Guinea Pigs; Ileum; In Vitro Techniques; Isomerism; Lethal Dose 50; Male; Methacholine Compounds; Mice; Muscle Contraction; Parasympatholytics; Pilocarpine; Piperidines; Piperidones; Pupil; Rats; Salivation; Tremorine | 1971 |
[Pharmacological studies of 2-(1-piperidino)-ethyl benzilate ethylbromide (PB-106)].
Topics: Acetylcholine; Animals; Anura; Atropine; Barium; Benzilates; Blood Glucose; Blood Pressure; Blood Vessels; Bromides; Cats; Dogs; Female; Gastric Juice; Guinea Pigs; Heart; Hexamethonium Compounds; Histamine Antagonists; In Vitro Techniques; Intestines; Male; Mice; Nicotine; Nictitating Membrane; Pilocarpine; Piperidines; Rabbits; Rats; Regional Blood Flow; Saliva; Scopolamine; Seminal Vesicles; Tranquilizing Agents; Ureter; Urinary Bladder | 1969 |
M2-type muscarinic receptors mediate prejunctional inhibition of norepinephrine release in the human iris-ciliary body.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Child; Ciliary Body; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Middle Aged; Muscarine; Norepinephrine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
The role of acetylcholine in regulating secretory responsiveness in rat sweat glands.
Topics: Acetylcholine; Age Factors; Animals; Atropine; Parasympatholytics; Pilocarpine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sweat Glands; Time Factors | 1995 |
Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea-pigs.
Topics: Administration, Inhalation; Allergens; Animals; Asthma; Benzodiazepinones; Bronchial Hyperreactivity; Diamines; Disease Models, Animal; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart; Histamine; Hypersensitivity; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle, Smooth; Neuromuscular Junction; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1995 |
Two inbred rat sublines that differ in spontaneous yawning behavior also differ in their responses to cholinergic and dopaminergic drugs.
Topics: Animals; Apomorphine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Parasympathomimetics; Physostigmine; Pilocarpine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Dopamine; Species Specificity; Yawning | 1993 |
Assessment of the muscarinic receptor subtypes involved in pilocarpine-induced seizures in mice.
Topics: Animals; Atropine; Cerebral Ventricles; Injections, Intraventricular; Male; Mice; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Seizures | 1994 |
Selective inactivation of muscarinic M2 and M3 receptors in guinea-pig ileum and atria in vitro.
Topics: Alkylating Agents; Animals; Atropine; Diamines; Dioxolanes; Diphenylacetic Acids; Guinea Pigs; Heart; Heart Atria; Ileum; In Vitro Techniques; Isometric Contraction; Male; Muscarinic Antagonists; Muscle, Smooth; Parasympatholytics; Phenoxybenzamine; Pilocarpine; Piperidines; Receptors, Muscarinic | 1993 |
Binding of the labelled muscarinic toxin 125I-MT1 to rat brain muscarinic M1 receptors.
Topics: Alkaloids; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Elapid Venoms; Furans; Gallamine Triethiodide; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Naphthalenes; Oxotremorine; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Protein Binding; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Synaptic Membranes; Tubocurarine | 1996 |
Effects of tachykinin NK1 receptor antagonists on vagal hyperreactivity and neuronal M2 muscarinic receptor function in antigen challenged guinea-pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Electric Stimulation; Eosinophilia; Guinea Pigs; Lung; Neurokinin A; Neurokinin-1 Receptor Antagonists; Ovalbumin; Peptide Fragments; Pilocarpine; Piperidines; Quinuclidines; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Tachykinin; Specific Pathogen-Free Organisms; Substance P; Trachea; Vagus Nerve | 1998 |
Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current.
Topics: Action Potentials; Animals; Atrial Function; Binding, Competitive; Dogs; Electrophysiology; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; Male; Membrane Potentials; Microelectrodes; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Parasympatholytics; Pilocarpine; Piperidines; Potassium Channels; Receptor, Muscarinic M3; Receptors, Muscarinic; Time Factors | 1999 |
Effects of neurokinin receptor antagonists in virus-infected airways.
Topics: Animals; Benzamides; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Electric Stimulation; Female; Guinea Pigs; Leukocyte Count; Leukocytes; Lung; Muscarinic Agonists; Neurokinin-1 Receptor Antagonists; Pilocarpine; Piperidines; Quinuclidines; Receptors, Muscarinic; Receptors, Neurokinin-2; Respirovirus; Respirovirus Infections; Vagus Nerve | 2000 |
Efficacy of muscarinic stimulation and mode of excitation-contraction coupling in bovine trachealis muscle.
Topics: Acetylcholine; Animals; Calcium; Cattle; Cromakalim; Diamines; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Stress, Mechanical; Tetraethylammonium; Trachea | 2000 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pilocarpine; Piperidines; Receptors, Muscarinic; Urinary Bladder | 2001 |
Characteristics of learning and memory impairment induced by delta9-tetrahydrocannabinol in rats.
Topics: Animals; Avoidance Learning; Discrimination Learning; Dronabinol; Hallucinogens; Injections, Intraventricular; Learning Disabilities; Maze Learning; Memory Disorders; Memory, Short-Term; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Piperidines; Pyrazoles; Rats; Rimonabant; Scopolamine | 2001 |
Acetylcholine splitting enzymes in salivary glands after prolonged treatment with pilocarpine and an atropine-like substance.
Topics: Acetylcholine; Amides; Anesthetics, Local; Atropine; Cholinesterases; Epinephrine; Humans; Pilocarpine; Piperidines; Salivary Glands | 1956 |
Amine oxidase in salivary glands after prolonged treatment with pilocarpine or an atropine-like substance.
Topics: Amides; Amines; Atropine; Humans; Monoamine Oxidase; Oxidoreductases; Pilocarpine; Piperidines; Salivary Glands | 1956 |
Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats.
Topics: Age Factors; Animals; Autoreceptors; Chronic Disease; Entorhinal Cortex; Epilepsy, Generalized; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenols; Pilocarpine; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 2006 |
Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus.
Topics: Animals; Anticonvulsants; Astrocytes; Calcium; Calcium Signaling; Cell Death; Chelating Agents; Disease Models, Animal; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; Mice; Neurons; Patch-Clamp Techniques; Pilocarpine; Piperidines; Receptors, Glutamate; Status Epilepticus; Time Factors | 2007 |
Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake.
Topics: Animals; Blood Pressure; Diamines; Drinking Behavior; Heart Rate; Hypertension; Injections, Intraventricular; Male; Muscarinic Antagonists; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Saliva; Tropicamide | 2008 |
Drug-induced sialorrhoea and excessive saliva accumulation.
Topics: Antipsychotic Agents; Benzodiazepines; Cholinesterase Inhibitors; Clozapine; Deglutition Disorders; Donepezil; Galantamine; Humans; Hypnotics and Sedatives; Indans; Phenylcarbamates; Pilocarpine; Piperidines; Quality of Life; Risperidone; Rivastigmine; Sialorrhea | 2009 |
The role of nicotinic receptors in the amelioration of cholinesterase inhibitors in scopolamine-induced memory deficits.
Topics: Animals; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Indans; Learning Disabilities; Male; Maze Learning; Mecamylamine; Muscarinic Agonists; Nicotine; Nicotinic Antagonists; Physostigmine; Pilocarpine; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Theta Rhythm | 2009 |
Salivation triggered by pilocarpine involves aquaporin-5 in normal rats but not in irradiated rats.
Topics: Animals; Aquaporin 5; Calcium; Male; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Pilocarpine; Piperidines; Protein Transport; Radiation Injuries, Experimental; Radioligand Assay; Rats; Rats, Sprague-Dawley; Saliva; Salivation; Whole-Body Irradiation; Xerostomia | 2009 |
The antiarrhythmic effect and possible ionic mechanisms of pilocarpine on animal models.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Disease Models, Animal; Female; Guinea Pigs; Male; Microscopy, Confocal; Muscarinic Agonists; Muscarinic Antagonists; Myocytes, Cardiac; Ouabain; Pilocarpine; Piperidines; Rats; Rats, Wistar; Receptor, Muscarinic M3; Time Factors | 2009 |
Effects of pilocarpine and cevimeline on Ca2+ mobilization in rat parotid acini and ducts.
Topics: Animals; Calcium; Calcium Signaling; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Pilocarpine; Piperidines; Quinuclidines; Rats; Receptors, Muscarinic; Thiophenes | 2009 |
Cholinergic autoantibodies from primary Sjögren's syndrome modulate submandibular gland Na+/K+-ATPase activity via prostaglandin E2 and cyclic AMP.
Topics: Adult; Animals; Autoantibodies; Cells, Cultured; Cyclic AMP; Dinoprostone; Female; Humans; Immunoglobulin G; Immunologic Factors; Inflammation Mediators; Keratoconjunctivitis Sicca; Male; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Piperidines; Pirenzepine; Potassium; Rats; Rats, Wistar; Receptor, Muscarinic M3; Sjogren's Syndrome; Sodium-Potassium-Exchanging ATPase; Submandibular Gland; Tropicamide; Xerostomia | 2010 |
Piperine protects epilepsy associated depression: a study on role of monoamines.
Topics: Alkaloids; Anhedonia; Animals; Anticonvulsants; Behavior, Animal; Benzodioxoles; Biogenic Monoamines; Brain Chemistry; Chromatography, Thin Layer; Convulsants; Depression; Epilepsy; Female; Fluoxetine; Male; Motor Activity; Pilocarpine; Piperidines; Polyunsaturated Alkamides; Postural Balance; Rats; Serotonin; Spectrophotometry, Infrared; Status Epilepticus; Swimming | 2011 |
Functional M3 cholinoreceptors are present in pacemaker and working myocardium of murine heart.
Topics: Action Potentials; Animals; Diamines; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Pilocarpine; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sinoatrial Node | 2012 |
Inactivation of the constitutively active ghrelin receptor attenuates limbic seizure activity in rodents.
Topics: Analysis of Variance; Animals; Anticonvulsants; Calcium; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Ghrelin; Green Fluorescent Proteins; HEK293 Cells; Hippocampus; Humans; In Vitro Techniques; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Muscarinic Agonists; Neurons; Patch-Clamp Techniques; Pilocarpine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Ghrelin; Seizures; Severity of Illness Index; Species Specificity; Transfection | 2012 |
Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis.
Topics: Acetylcysteine; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Male; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Pilocarpine; Piperidines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Compounds | 2013 |
Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms.
Topics: Alkaloids; Amino Acids; Animals; Anticonvulsants; Antioxidants; Atropine; Benzodioxoles; Biogenic Monoamines; Brain; Diazepam; Disease Models, Animal; Epilepsy; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Memantine; Mice; Nimodipine; Nitrites; Pilocarpine; Piperidines; Polyunsaturated Alkamides; Seizures; Tumor Necrosis Factor-alpha | 2013 |
Effect of selective stimulation of muscarinic M3 cholinoceptors on electrical and contractile activity of rat ventricular myocardium.
Topics: Action Potentials; Animals; Diamines; Heart; Muscarinic Agonists; Muscarinic Antagonists; Myocardial Contraction; Myocardium; Parasympatholytics; Pilocarpine; Piperidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ventricular Function | 2013 |
Donepezil reverses intermittent stress-induced generalized chronic pain syndrome in mice.
Topics: Analgesics, Opioid; Animals; Chronic Pain; Donepezil; Fibromyalgia; Hyperalgesia; Indans; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Morphine; Muscarinic Agonists; Nootropic Agents; Pain Measurement; Pilocarpine; Piperidines; Stress, Psychological | 2015 |
Different Myocardial Sensitivity in Newborn and Mature Rats to Selective Stimulation of M3 Cholinoreceptors.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Diamines; Heart Atria; Heart Ventricles; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Piperidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2015 |
Cannabinoid and nitric oxide signaling interplay in the modulation of hippocampal hyperexcitability: Study on electrophysiological and behavioral models of temporal lobe epilepsy in the rat.
Topics: Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Hippocampus; Indazoles; Male; Morpholines; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Pilocarpine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2015 |
Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy.
Topics: Action Potentials; Animals; Dentate Gyrus; Inhibitory Postsynaptic Potentials; Interneurons; Male; Pilocarpine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Status Epilepticus; Synapses | 2016 |
Status Epilepticus Enhances Depotentiation after Fully Established LTP in an NMDAR-Dependent but GluN2B-Independent Manner.
Topics: Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Phenols; Pilocarpine; Piperidines; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Up-Regulation | 2016 |
Diverse Effects of an Acetylcholinesterase Inhibitor, Donepezil, on Hippocampal Neuronal Death after Pilocarpine-Induced Seizure.
Topics: Animals; Cell Death; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Administration Schedule; Epilepsy, Temporal Lobe; Hippocampus; Indans; Male; Neurons; Nootropic Agents; Oxidative Stress; Pilocarpine; Piperidines; Rats, Sprague-Dawley; Seizures | 2017 |
Does status epilepticus modify the effect of ifenprodil on cortical epileptic afterdischarges in immature rats?
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Brain Waves; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Lithium Chloride; Male; Pilocarpine; Piperidines; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 2018 |
Decreased vesicular acetylcholine transporter related to memory deficits in epilepsy: A [
Topics: Acholeplasmataceae; Animals; Brain; Chronic Disease; Disease Models, Animal; Epilepsy; Fluorodeoxyglucose F18; Male; Maze Learning; Memory Disorders; Muscarinic Agonists; Naphthols; Pilocarpine; Piperidines; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Vesicular Acetylcholine Transport Proteins | 2018 |
Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epilepsy-associated depression in the LiCl-pilocarpine post-status epilepticus rat model.
Topics: Animals; Astrocytes; Brain; Depression; Depressive Disorder; Disease Models, Animal; Epilepsy; Epoxide Hydrolases; Hippocampus; Lithium Chloride; Male; Microglia; Neurons; Phenylurea Compounds; Pilocarpine; Piperidines; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Tumor Necrosis Factor-alpha | 2019 |
Upregulated SHP-2 expression in the epileptogenic zone of temporal lobe epilepsy and various effects of SHP099 treatment on a pilocarpine model.
Topics: Adolescent; Adult; Animals; Brain; Convulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Humans; Male; Mice; Mice, Inbred C57BL; Pilocarpine; Piperidines; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pyrimidines; Up-Regulation; Young Adult | 2020 |
Pilocarpine induces the residual secretion of salivary fluid in perfused submandibular glands of rats.
Topics: Animals; Male; Muscarinic Antagonists; Oxygen Consumption; Perfusion; Pilocarpine; Piperidines; Rats, Wistar; Saliva; Submandibular Gland; Tetrodotoxin | 2019 |