pilocarpine has been researched along with n-methylscopolamine in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (30.95) | 18.7374 |
| 1990's | 15 (35.71) | 18.2507 |
| 2000's | 8 (19.05) | 29.6817 |
| 2010's | 6 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bacáková, L; El-Fakahany, EE; Jakubík, J; Tucek, S | 1 |
| Maeda, N; Matsuoka, N; Yamaguchi, I | 1 |
| Nathanson, NM; Scherer, NM | 1 |
| Bortolotto, ZA; Cavalheiro, EA; Leite, JP | 1 |
| Hamburger-Bar, R; Lerer, B; Roth, D | 1 |
| Hollingsworth, PJ; Smith, CB | 1 |
| Brunner, F; Christophe, J; Gillard, M; Svoboda, M; Waelbroeck, M | 1 |
| Mueller, K | 1 |
| Christophe, J; Gillard, M; Waelbroeck, M | 1 |
| Burgen, AS | 1 |
| Ahlenius, S; Larsson, K | 1 |
| Furukawa, T; Imaizumi, J; Mizuki, Y; Noda, Y; Ushijima, I; Yamada, K; Yamada, M | 1 |
| Christophe, J; Dehaye, JP; Poloczek, P; Winand, J | 1 |
| Albinus, M; Winne, D | 1 |
| Bárány, E; Berrie, CP; Birdsall, NJ; Burgen, AS; Hulme, EC | 1 |
| Glick, SD; Guido, RA | 1 |
| Marini, JL | 1 |
| el-Fakahany, EE; Wang, SZ | 1 |
| Barnes, JC; Dennes, RP | 1 |
| Freedman, SB; Patel, S | 1 |
| Starr, BS; Starr, MS | 1 |
| Kikuchi de Beltrán, K; Kobayashi, M; Koshikawa, N; Miwa, Y; Stephenson, JD | 1 |
| Boddeke, H; Enz, A; Rudin, M; Sauter, A; Shapiro, G | 1 |
| Segerberg, MA; Stretton, AO | 1 |
| Cristi, C; Raithby, A; Snider, M; Tanner, C; Vanderwolf, CH | 1 |
| Coulter, DA; Gibbs, JW; Holloway, KL; Lin, DD; Shumate, MD | 1 |
| Lu, Y; Shi, H; Wang, H; Wang, Z; Yang, B | 1 |
| Curtis, CA; Hulme, EC; Ward, SD | 1 |
| De Bruin, VM; De Sousa, FC; Marinho, MM; Viana, GS | 1 |
| Beck, H; Becker, AJ; Chen, J; Marechal, D; Sochivko, D; Wiestler, OD | 1 |
| Costa-Lotufo, LV; de Bruin, VM; de Oliveira, AA; Fonteles, MM; Lima, IS; Nascimento, VS; Viana, GS | 1 |
| Bloodworth, L; Cui, Y; Gautam, D; Heard, TS; Miller, G; Wess, J | 1 |
| Lian, XY; Stringer, JL; Zhang, ZZ | 1 |
| El-Fakahany, EE; Grant, MK | 1 |
| Gordon, RK; Nambiar, MP; Ratcliffe, RH; Rezk, PE; Steele, KE; Tetz, LM | 1 |
| El-Fakahany, EE; Grant, MK; Noetzel, MJ | 1 |
| Dijkhuizen, RM; Hoff, EI; Otte, WM; Steinbusch, HW; van der Marel, K; van Oostenbrugge, RJ | 1 |
| Civelli, O; Gohil, K; Okumura, SM; Parks, GS | 1 |
| Canteras, NS; De Lima, TC; Duarte, FS; Duzzioni, M; Gavioli, EC; Hoeller, AA | 1 |
| Baldwin, R; Lumley, L; Niquet, J; Norman, K; Suchomelova, L; Wasterlain, CG | 1 |
| Aktar, M; Brulet, R; Cho, KO; Hsieh, J; Zhu, J | 1 |
| Fu, L; Liu, K; Mori, S; Nishibori, M; Takahashi, H; Teshigawara, K; Wake, H; Yoshino, T | 1 |
42 other study(ies) available for pilocarpine and n-methylscopolamine
| Article | Year |
|---|---|
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
Topics: Acetylcholine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Ligands; Muscarinic Agonists; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives | 1997 |
Septohippocampal cholinergic pathway and penile erections induced by dopaminergic and cholinergic stimulants.
Topics: Amantadine; Animals; Apomorphine; Brain; Denervation; Dopamine Agents; Dose-Response Relationship, Drug; Hippocampus; Male; N-Methylscopolamine; Neural Pathways; Parasympathetic Nervous System; Parasympathomimetics; Penile Erection; Pilocarpine; Rats; Scopolamine; Scopolamine Derivatives; Sulpiride | 1990 |
Differential regulation by agonist and phorbol ester of cloned m1 and m2 muscarinic acetylcholine receptors in mouse Y1 adrenal cells and in Y1 cells deficient in cAMP-dependent protein kinase.
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Animals; Colforsin; Concanavalin A; Cyclic AMP; Endocytosis; Mice; N-Methylscopolamine; Phorbol Esters; Pilocarpine; Protein Kinases; Quinuclidinyl Benzilate; Receptors, Muscarinic; Recombinant Fusion Proteins; Scopolamine Derivatives; Second Messenger Systems; Thionucleotides; Tumor Cells, Cultured | 1990 |
Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy.
Topics: Aggression; Amygdala; Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Hippocampus; Humans; Limbic System; N-Methylscopolamine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Recurrence; Scopolamine Derivatives; Seizures | 1990 |
Peripheral versus central manifestations in the toxic interaction of lithium and pilocarpine.
Topics: Animals; Brain; Chlorides; Cholinergic Fibers; Dose-Response Relationship, Drug; Drug Synergism; Lithium; Lithium Chloride; Male; N-Methylscopolamine; Peripheral Nerves; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives | 1989 |
Effects of muscarinic receptor agonists and antagonists on alpha 2-adrenoceptors in rat brain.
Topics: Animals; Atropine; Atropine Derivatives; Brain; Clonidine; Male; N-Methylscopolamine; Neurons; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Time Factors | 1989 |
Bretylium tosylate binds preferentially to muscarinic receptors labelled with [3H]oxotremorine M (SH or 'high affinity' receptors) in rat heart and brain cortex.
Topics: Animals; Bretylium Compounds; Bretylium Tosylate; Cerebral Cortex; Guanosine Triphosphate; Heart; In Vitro Techniques; Male; Membranes; Myocardium; N-Methylscopolamine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
Voltammetric evidence in vivo of cholinergic modulation of extracellular ascorbic acid and uric acid in rat striatum.
Topics: Animals; Ascorbic Acid; Cholinergic Fibers; Corpus Striatum; Electrochemistry; Male; N-Methylscopolamine; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Uric Acid | 1987 |
Muscarinic receptor heterogeneity in rat central nervous system. II. Brain receptors labeled by [3H]oxotremorine-M correspond to heterogeneous M2 receptors with very high affinity for agonists.
Topics: Animals; Binding, Competitive; Brain; Carbachol; Cerebral Cortex; Kinetics; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
The effects of agonists on the components of the cardiac muscarinic receptor.
Topics: Acetylcholine; Animals; Guanylyl Imidodiphosphate; In Vitro Techniques; Myocardium; N-Methylscopolamine; Parasympathomimetics; Pilocarpine; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
Central muscarinic receptors and male rat sexual behavior: facilitation by oxotremorine but not arecoline or pilocarpine in methscopolamine pretreated animals.
Topics: Animals; Arecoline; Dose-Response Relationship, Drug; Female; Male; N-Methylscopolamine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Sexual Behavior, Animal | 1985 |
Characteristics of yawning behavior induced by apomorphine, physostigmine and pilocarpine.
Topics: Animals; Apomorphine; Behavior, Animal; Haloperidol; Male; Mecamylamine; N-Methylscopolamine; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Time Factors | 1985 |
Characterization of muscarinic cholinergic receptors on rat pancreatic acini by N-[3H]methylscopolamine binding. Their relationship with calcium 45 efflux and amylase secretion.
Topics: Amylases; Animals; Binding, Competitive; Calcium; Carbachol; Male; N-Methylscopolamine; Pancreas; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Time Factors | 1984 |
Subclasses of muscarinic receptors in isolated gastric mucosal cells: receptor characterization and parietal cell function.
Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Carbachol; Dogs; Gastric Mucosa; Guanine Nucleotides; Guinea Pigs; In Vitro Techniques; Male; Models, Biological; N-Methylscopolamine; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1983 |
The binding properties of the muscarinic receptors of the cynomolgus monkey ciliary body and the response to the induction of agonist subsensitivity.
Topics: Animals; Benzodiazepinones; Carbachol; Ciliary Body; Guanylyl Imidodiphosphate; Kinetics; Macaca fascicularis; N-Methylscopolamine; Pilocarpine; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1982 |
Scopolamine self-administration: cholinergic involvement in reward mechanisms.
Topics: Animals; Arecoline; Atropine; Behavior, Animal; Female; Mecamylamine; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Scopolamine; Scopolamine Derivatives; Self Administration | 1982 |
Pilocarpine, a non-hallucinogenic cholinergic agonist, elicits limb flicking in cats.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Female; Grooming; Lisuride; Lysergic Acid Diethylamide; Male; N-Methylscopolamine; Pilocarpine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1981 |
Application of transfected cell lines in studies of functional receptor subtype selectivity of muscarinic agonists.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Hydrolysis; N-Methylscopolamine; Phosphatidylinositols; Pilocarpine; Receptors, Muscarinic; Scopolamine Derivatives; Stimulation, Chemical; Substrate Specificity; Transfection | 1993 |
Attenuation of scopolamine-induced spatial memory deficits in the rat by cholinomimetic and non-cholinomimetic drugs using a novel task in the 12-arm radial maze.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bridged Bicyclo Compounds; Cholinergic Agents; Dose-Response Relationship, Drug; Imidazoles; Injections, Intraventricular; Losartan; Male; Maze Learning; Memory; Memory, Short-Term; N-Methylscopolamine; Parasympatholytics; Physostigmine; Pilocarpine; Rats; Scopolamine; Scopolamine Derivatives; Space Perception; Spiro Compounds; Tetrazoles | 1993 |
The muscarinic receptor agonist L-658,903 modulates the in vivo accumulation of inositol monophosphates in mouse brain.
Topics: Animals; Binding Sites; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Lithium Chloride; Male; Mice; N-Methylscopolamine; Oxadiazoles; Oxotremorine; Parasympatholytics; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives | 1994 |
Seizure promotion by D1 agonists does not correlate with other dopaminergic properties.
Topics: Adenylyl Cyclases; Animals; Behavior, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Enzyme Activation; Limbic System; Male; Mice; Mice, Inbred Strains; N-Methylscopolamine; Parasympatholytics; Pilocarpine; Receptors, Dopamine D1; Scopolamine Derivatives; Seizures | 1993 |
Further evidence for a functional dorsal-ventral division of the rat striatum: GABAergic involvement in oral movements.
Topics: Animals; Apomorphine; Behavior, Animal; Benzamides; Benzazepines; Carbachol; Corpus Striatum; Dopamine; Flunitrazepam; gamma-Aminobutyric Acid; Jaw; Male; Muscimol; N-Methylscopolamine; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives | 1993 |
SDZ ENS 163 a novel pilocarpine like drug: pharmacological in vitro and in vivo profile.
Topics: Acetylcholine; Animals; Brain; CHO Cells; Cricetinae; Ganglia, Sympathetic; Guinea Pigs; Ileum; Imidazoles; Male; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Pilocarpine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Thiophenes | 1993 |
Actions of cholinergic drugs in the nematode Ascaris suum. Complex pharmacology of muscle and motorneurons.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Ascaris suum; Choline; Electrophysiology; In Vitro Techniques; Membrane Potentials; Microelectrodes; Motor Neurons; Muscle Contraction; Muscles; N-Methylscopolamine; Neuromuscular Junction; Nicotine; Parasympatholytics; Parasympathomimetics; Pilocarpine; Scopolamine Derivatives; Synapses | 1993 |
Effects of some cholinergic agonists on neocortical slow wave activity in rats with basal forebrain lesions.
Topics: Animals; Arecoline; Body Temperature; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Kainic Acid; Male; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pilocarpine; Prosencephalon; Rats; Scopolamine Derivatives; Tacrine | 1993 |
GABA(A) receptor function in epileptic human dentate granule cells: comparison to epileptic and control rat.
Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; N-Methylscopolamine; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Temporal Lobe; Zinc | 1998 |
Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current.
Topics: Action Potentials; Animals; Atrial Function; Binding, Competitive; Dogs; Electrophysiology; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; Male; Membrane Potentials; Microelectrodes; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Parasympatholytics; Pilocarpine; Piperidines; Potassium Channels; Receptor, Muscarinic M3; Receptors, Muscarinic; Time Factors | 1999 |
Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function.
Topics: Acetylcholine; Alanine; Animals; Atropine; Binding, Competitive; COS Cells; Immunohistochemistry; Ligands; Muscarinic Agonists; Muscarinic Antagonists; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Phosphatidylinositols; Pilocarpine; Protein Structure, Tertiary; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Tyrosine | 1999 |
Behavioral and neurochemical alterations after lithium-pilocarpine administration in young and adult rats: a comparative study.
Topics: Age Factors; Animals; Atropine; Behavior, Animal; Brain; Lithium; Male; N-Methylscopolamine; Pilocarpine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Muscarinic; Spiperone | 2000 |
Activity-induced expression of common reference genes in individual cns neurons.
Topics: Actins; Animals; Central Nervous System; Convulsants; Cyclophilin A; Epilepsy; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypoxanthine Phosphoribosyltransferase; Male; N-Methylscopolamine; Neurons; Pilocarpine; Rats; Rats, Wistar; Synaptophysin | 2001 |
Attenuating effects of melatonin on pilocarpine-induced seizures in rats.
Topics: Age Factors; Animals; Anticonvulsants; Female; gamma-Aminobutyric Acid; Melatonin; N-Methylscopolamine; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A; Seizures | 2002 |
Cholinergic stimulation of salivary secretion studied with M1 and M3 muscarinic receptor single- and double-knockout mice.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Gene Expression; Mice; Mice, Knockout; Muscarinic Agonists; N-Methylscopolamine; Pilocarpine; Polymerase Chain Reaction; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Cholinergic; Salivary Glands; Salivation; Time Factors; Tritium | 2004 |
Anticonvulsant activity of ginseng on seizures induced by chemical convulsants.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Dose-Response Relationship, Drug; Drug Administration Schedule; Ginsenosides; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Kainic Acid; Male; N-Methylscopolamine; Neurons; Panax; Pentylenetetrazole; Phytotherapy; Pilocarpine; Plant Extracts; Rats; Rats, Sprague-Dawley; Seizures | 2005 |
Persistent binding and functional antagonism by xanomeline at the muscarinic M5 receptor.
Topics: Animals; Carbachol; CHO Cells; Cricetinae; Inositol Phosphates; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Pilocarpine; Pyridines; Receptor, Muscarinic M5; Thiadiazoles | 2005 |
Development of a rat pilocarpine model of seizure/status epilepticus that mimics chemical warfare nerve agent exposure.
Topics: Animals; Anticonvulsants; Behavior, Animal; Body Temperature; Brain; Chemical Warfare Agents; Cholinergic Antagonists; Drug Evaluation, Preclinical; Electroencephalography; Heart Rate; Lethal Dose 50; Lithium Chloride; Male; Models, Animal; Motor Activity; Muscarinic Agonists; N-Methylscopolamine; Neuroprotective Agents; Neurotoxicity Syndromes; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Soman; Status Epilepticus | 2006 |
Mechanisms of M3 muscarinic receptor regulation by wash-resistant xanomeline binding.
Topics: Animals; Atropine; Binding Sites; Carbachol; Cell Line, Transformed; Cricetinae; Drug Interactions; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Muscarinic Agonists; N-Methylscopolamine; Phosphatidylinositols; Pilocarpine; Pyridines; Quinuclidinyl Benzilate; Receptor, Muscarinic M3; Thiadiazoles; Time Factors; Transfection | 2009 |
Pharmacological magnetic resonance imaging of muscarinic acetylcholine receptor activation in rat brain.
Topics: Animals; Blood Pressure; Brain; Cerebral Cortex; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Pilocarpine; Rats; Rats, Inbred Lew; Receptors, Muscarinic | 2010 |
Mice lacking Melanin Concentrating Hormone 1 receptor are resistant to seizures.
Topics: Animals; Disease Models, Animal; Kaplan-Meier Estimate; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylscopolamine; Pentylenetetrazole; Pilocarpine; Receptors, Somatostatin; Seizures | 2010 |
NK1 receptors antagonism of dorsal hippocampus counteract the anxiogenic-like effects induced by pilocarpine in non-convulsive Wistar rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Dipeptides; Dose-Response Relationship, Drug; Hippocampus; Indoles; Male; Maze Learning; Muscarinic Agonists; N-Methylscopolamine; Parasympatholytics; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2014 |
Midazolam-ketamine dual therapy stops cholinergic status epilepticus and reduces Morris water maze deficits.
Topics: Animals; Anticonvulsants; Brain; Cholinergic Agents; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Ketamine; Learning Disabilities; Lithium Chloride; Male; Maze Learning; Midazolam; N-Methylscopolamine; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Valproic Acid | 2016 |
Mice with conditional NeuroD1 knockout display reduced aberrant hippocampal neurogenesis but no change in epileptic seizures.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Disease Models, Animal; Doublecortin Domain Proteins; Epilepsy; Female; Gene Expression Regulation; Hippocampus; Homeodomain Proteins; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Muscarinic Agonists; N-Methylscopolamine; Nestin; Neurogenesis; Neurons; Neuropeptides; Pilocarpine; Tumor Suppressor Proteins; Up-Regulation | 2017 |
Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.
Topics: Animals; Antibodies, Monoclonal; Blood-Brain Barrier; Cerebral Cortex; Female; Hippocampus; HMGB1 Protein; Immunologic Factors; Mice, Inbred C57BL; N-Methylscopolamine; Pilocarpine; Status Epilepticus; Treatment Outcome | 2017 |