Compounds > pilocarpine
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pilocarpine and lovastatin

pilocarpine has been researched along with lovastatin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's8 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arida, RM; Cavalheiro, EA; Colugnati, DB; Cysneiros, RM; de Albuquerque, M; Rangel, P; Scorza, CA; Scorza, FA1
Amado, D; Araujo, TR; Argañaraz, GA; Bandeira, Tde A; Cavalheiro, EA; Frangiotti, MI; Gouveia, TL; Naffah-Mazzacoratti, Mda G; Perosa, SR; Scorza, FA; Silva, JA; Silva, Mde P; Silva, MJ1
Chen, IC; Jaw, T; Lee, CY; Liou, HH; Tseng, HC1
Cavalheiro, EA; de Almeida, AC; Feliciano, RS; Frangiotti, MI; Gouveia, TL; Iha, HA; Naffah-Mazzacoratti, MG; Perosa, SR; Scorza, FA; Silva, JA1
Abdanipour, A; Deheshjo, F; Jafari Anarkooli, I; Nejatbakhsh, R; Sohrabi, D1
Abdanipour, A; Anarkooli, IJ; Ganjkhani, M; Moradi, P1

Reviews

1 review(s) available for pilocarpine and lovastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for pilocarpine and lovastatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Lovastatin reduces neuronal cell death in hippocampal CA1 subfield after pilocarpine-induced status epilepticus: preliminary results.
    Arquivos de neuro-psiquiatria, 2005, Volume: 63, Issue:4

    Topics: Animals; Cell Count; Cell Death; Disease Models, Animal; Hippocampus; Lovastatin; Male; Muscarinic Agonists; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus

2005
Lovastatin decreases the synthesis of inflammatory mediators in the hippocampus and blocks the hyperthermia of rats submitted to long-lasting status epilepticus.
    Epilepsy & behavior : E&B, 2011, Volume: 20, Issue:1

    Topics: Analysis of Variance; Animals; Body Temperature; Cytokines; Fever; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lovastatin; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Status Epilepticus

2011
Lovastatin modulates glycogen synthase kinase-3β pathway and inhibits mossy fiber sprouting after pilocarpine-induced status epilepticus.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Animals; Anticholesteremic Agents; Blotting, Western; Dentate Gyrus; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lobe; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Intercellular Signaling Peptides and Proteins; Lovastatin; Male; Mossy Fibers, Hippocampal; Muscarinic Agonists; Nerve Tissue Proteins; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus

2012
Lovastatin decreases the synthesis of inflammatory mediators during epileptogenesis in the hippocampus of rats submitted to pilocarpine-induced epilepsy.
    Epilepsy & behavior : E&B, 2014, Volume: 36

    Topics: Animals; Anticholesteremic Agents; Cytokines; Disease Models, Animal; Epilepsy; Gene Expression Regulation; Hippocampus; Lovastatin; Male; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar; RNA, Messenger

2014
Neuroprotective effect of lovastatin through down-regulation of pro-apoptotic Mst1 gene expression in rat model pilocarpine epilepsy.
    Neurological research, 2018, Volume: 40, Issue:10

    Topics: Animals; Disease Models, Animal; Down-Regulation; Epilepsy; Hepatocyte Growth Factor; Hippocampus; In Situ Nick-End Labeling; Lovastatin; Male; Neuroprotective Agents; NF-E2-Related Factor 2; Pilocarpine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger

2018
Neuroprotective effects of lovastatin in the pilocarpine rat model of epilepsy according to the expression of neurotrophic factors.
    Metabolic brain disease, 2019, Volume: 34, Issue:4

    Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Ciliary Neurotrophic Factor; Disease Models, Animal; Epilepsy, Temporal Lobe; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Lovastatin; Male; Nerve Growth Factors; Neurons; Neuroprotective Agents; Neurotrophin 3; Pilocarpine; Rats; Rats, Wistar

2019