Page last updated: 2024-08-17

pilocarpine and indomethacin

pilocarpine has been researched along with indomethacin in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's3 (15.79)18.2507
2000's2 (10.53)29.6817
2010's5 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Varró, V1
Lotti, VJ; Pawlowski, N1
Becker, U; Pham Duy, T; Wollensak, J1
Barr, HA; Nicholas, TE; Power, JH1
Brown, DW; Marzulli, FN1
Deutsch, AR; Hiatt, RL1
Berti, F; Folco, G; Mandelli, V; Nava, G; Omini, C; Sautebin, L1
Barr, HA; Nicholas, TE1
Fredriksen, TA; Saunte, C; Sjaastad, O; Spierings, EL; Sulg, I; Wysocka Bakowska, MM1
Chernick, V; Ioffe, S; Jansen, AH1
Fryer, AD; Okanlami, OA1
Fryer, AD; Jacoby, DB; Kahn, RM; Okanlami, OA1
Bauer, B; Hartz, AM; Miller, DS; Pekcec, A; Potschka, H; Toellner, K1
Argaãaraz, GA; Cavalheiro, EA; Graça Naffah-Mazzacoratti, Md; Perosa, SR; Silva, JA; Vieira, MJ1

Reviews

1 review(s) available for pilocarpine and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for pilocarpine and indomethacin

ArticleYear
[Elevation of intraocular pressure following Nd-YAG laser capsulotomy. Pathogenesis and preventive therapy].
    Klinische Monatsblatter fur Augenheilkunde, 1987, Volume: 191, Issue:4

    Topics: Cataract Extraction; Drug Therapy, Combination; Humans; Indomethacin; Intraocular Pressure; Laser Therapy; Metipranolol; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Postoperative Complications

1987

Other Studies

17 other study(ies) available for pilocarpine and indomethacin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
[Experimental ulcer].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1975, Oct-01, Volume: 30, Issue:19

    Topics: Animals; Caffeine; Cats; Cattle; Chickens; Disease Models, Animal; Dogs; Ducks; Guinea Pigs; Haplorhini; Indomethacin; Mice; Peptic Ulcer; Phenylbutazone; Pilocarpine; Quinolines; Rabbits; Rats; Reserpine; Swine

1975
Prostaglandins mediate the ocular hypotensive action of the angiotensin converting enzyme inhibitor MK-422 (enalaprilat) in African green monkeys.
    Journal of ocular pharmacology, 1990,Spring, Volume: 6, Issue:1

    Topics: Administration, Topical; Angiotensin-Converting Enzyme Inhibitors; Animals; Cercopithecus; Chlorocebus aethiops; Dose-Response Relationship, Drug; Enalaprilat; Female; Indomethacin; Intraocular Pressure; Male; Ocular Hypertension; Pilocarpine; Prostaglandins; Sclera; Uvea

1990
Control of alveolar surfactant in rats at rest and during prolonged hyperpnoea: pharmacological evidence for two tissue pools of surfactant.
    British journal of pharmacology, 1988, Volume: 93, Issue:3

    Topics: Albuterol; Animals; Atropine; Autonomic Nervous System; Dimethyl Sulfoxide; In Vitro Techniques; Indomethacin; Phospholipids; Pilocarpine; Propranolol; Prostaglandins; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Respiration; Rest

1988
Aqueous humor pharmacodynamics studies in dogs.
    Annals of ophthalmology, 1971, Volume: 3, Issue:2

    Topics: Acetazolamide; Animals; Aqueous Humor; Ascorbic Acid; Biological Transport, Active; Carbon Radioisotopes; Dexamethasone; Dimethyl Sulfoxide; Dogs; Female; Hyaluronoglucosaminidase; Indomethacin; Intraocular Pressure; Lysergic Acid Diethylamide; Male; Ouabain; Perfusion; Pilocarpine; Proteins; Secretory Rate; Tritium; Water

1971
Effects of indomethacin on intraocular dynamics.
    American journal of ophthalmology, 1969, Volume: 68, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Glaucoma; Humans; Indomethacin; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Salicylates; Tonometry, Ocular

1969
beta-Adrenoceptor activation induces prostaglandin E2 generation in guinea-pig trachea.
    European journal of pharmacology, 1981, Jun-19, Volume: 72, Issue:2-3

    Topics: Albuterol; Animals; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Pilocarpine; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, beta; Trachea

1981
Control of release of surfactant phospholipids in the isolated perfused rat lung.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1981, Volume: 51, Issue:1

    Topics: Albuterol; Animals; Atropine; Bucladesine; Cyproheptadine; Dibutyryl Cyclic GMP; Hyperventilation; Indomethacin; Lung; Male; Perfusion; Phospholipids; Pilocarpine; Pulmonary Surfactants; Rats; Respiration; Tetrodotoxin; Theophylline

1981
"Hemicrania continua". An indomethacin responsive headache. II. Autonomic function studies.
    Cephalalgia : an international journal of headache, 1984, Volume: 4, Issue:4

    Topics: Autonomic Nervous System; Female; Humans; Indomethacin; Intraocular Pressure; Male; Middle Aged; Migraine Disorders; Pilocarpine; Reflex, Pupillary; Salivation; Skin Temperature; Sweating; Tears; Tyramine

1984
Drug-induced changes in fetal breathing activity and sleep state.
    Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:4

    Topics: Animals; Caffeine; Doxapram; Female; Fetus; Indomethacin; Pilocarpine; Pregnancy; Respiration; Sheep; Sleep; Sodium Cyanide

1983
Neuronal M2 muscarinic receptor function in guinea-pig lungs is inhibited by indomethacin.
    The American review of respiratory disease, 1993, Volume: 147, Issue:3

    Topics: Acetylcholine; Animals; Bronchoconstriction; Depression, Chemical; Drug Interactions; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; Indomethacin; Lung; Naproxen; Neurons; Parasympathetic Nervous System; Pilocarpine; Receptors, Muscarinic; Stereoisomerism; Vagus Nerve

1993
Viral infection induces dependence of neuronal M2 muscarinic receptors on cyclooxygenase in guinea pig lung.
    The Journal of clinical investigation, 1996, Jul-15, Volume: 98, Issue:2

    Topics: Animals; Antibodies, Viral; Benzoquinones; Cells, Cultured; Cyclooxygenase Inhibitors; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; Heart Rate; Indans; Indomethacin; Inflammation; Lung; Lung Diseases; Macaca mulatta; Neurons; Ozone; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Pilocarpine; Prostaglandin-Endoperoxide Synthases; Receptor, Muscarinic M2; Receptors, Muscarinic; Vagus Nerve

1996
Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling.
    Molecular pharmacology, 2008, Volume: 73, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Capillaries; Cyclooxygenase 2; Female; Glutamic Acid; Hippocampus; Indomethacin; Male; Mice; Mice, Inbred C57BL; Pilocarpine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Signal Transduction; Transcription, Genetic; Up-Regulation

2008
Indomethacin can downregulate the levels of inflammatory mediators in the hippocampus of rats submitted to pilocarpine-induced status epilepticus.
    Clinics (Sao Paulo, Brazil), 2014, Volume: 69, Issue:9

    Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Down-Regulation; Hippocampus; Indomethacin; Interleukin-1beta; Male; Monokines; Pilocarpine; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Status Epilepticus; Tumor Necrosis Factor-alpha

2014