pilocarpine has been researched along with gamma-aminobutyric acid in 124 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (6.45) | 18.7374 |
| 1990's | 23 (18.55) | 18.2507 |
| 2000's | 44 (35.48) | 29.6817 |
| 2010's | 46 (37.10) | 24.3611 |
| 2020's | 3 (2.42) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Davies, JA; Williams, J | 1 |
| Dudar, JD; Hadházy, P; Szerb, JC | 1 |
| Essenberg, RC; McSwain, JL; Sauer, JR | 1 |
| Gale, K; Maggio, R; Sohn, E | 1 |
| Gunawan, S; Treiman, DM; Walton, NY | 1 |
| Cavalheiro, EA | 1 |
| Kapur, J; Lothman, EW; Michelson, HB | 1 |
| Dryden, WF; Harvey, AL | 1 |
| Kanmori, K; Kuriyama, K; Taguchi, J; Yoneda, Y | 1 |
| Kuruvilla, A; Uretsky, NJ | 1 |
| Kikuchi de Beltrán, K; Kobayashi, M; Koshikawa, N; Miwa, Y; Stephenson, JD | 1 |
| Meyer, EM; Sjak-Shie, NN | 1 |
| Baldwin, RA; Baxter, CF; Wasterlain, CG | 1 |
| George, B; Kulkarni, SK | 1 |
| Cook, LL; Persinger, MA | 1 |
| Esclapez, M; Houser, CR | 3 |
| Bausch, SB; Chavkin, C | 1 |
| Matsumoto, K; Murakami, Y; Watanabe, H | 1 |
| Sankar, R; Shin, DH; Wasterlain, CG | 1 |
| Ebinger, G; Michotte, Y; Smolders, I; Van Belle, K | 1 |
| Bogaert, L; Ebinger, G; Michotte, Y; Smolders, I | 1 |
| Coulter, DA; Gibbs, JW; Shumate, MD | 1 |
| Ebinger, G; Khan, GM; Manil, J; Michotte, Y; Smolders, I | 1 |
| Ebinger, G; Khan, GM; Lindekens, H; Manil, J; Marvin, CA; Michotte, Y; Prikken, S; Smolders, I | 1 |
| Coulter, DA; Gibbs, JW; Holloway, KL; Lin, DD; Shumate, MD | 1 |
| Bouilleret, V; Fritschy, JM; Kiener, T; Loup, F | 1 |
| Ebinger, G; Khan, GM; Lindekens, H; Manil, J; Michotte, Y; Smolders, I | 1 |
| Agassandian, C; Ben-Ari, Y; Bernard, C; DeFelipe, J; Esclapez, M; Hirsch, JC; Merchán-Pérez, A | 1 |
| Chopde, CT; Deshmukh, VK; Kasture, VS | 1 |
| Czuczwar, SJ; Kleinrok, Z; Rejdak, K; Rejdak, R; Sieklucka-Dziuba, M; Stelmasiak, Z | 1 |
| Bialer, M; Ebinger, G; Khan, GM; Lindekens, H; Michotte, Y; Smolders, I | 1 |
| Ebinger, G; Khan, GM; Michotte, Y; Smolders, I | 1 |
| Molnár, P; Nadler, JV | 1 |
| André, V; Fritschy, JM; Marescaux, C; Nehlig, A | 1 |
| Hamani, C; Mello, LE | 1 |
| Costa-Lotufo, LV; de Bruin, VM; de Oliveira, AA; Fonteles, MM; Lima, IS; Nascimento, VS; Viana, GS | 1 |
| Buckmaster, PS; Yamawaki, R; Zhang, GF | 1 |
| Cavalheiro, EA; Sanabria, ER; Silva, AV; Spreafico, R | 1 |
| Tan, CY; Wainman, D; Weaver, DF | 1 |
| Draguhn, A; Frahm, C; Stief, F; Zuschratter, W | 1 |
| Grimee, R; Klitgaard, H; Margineanu, DG; Matagne, A; Vanneste-Goemaere, J | 1 |
| André, V; Ferrandon, A; Koning, E; Nehlig, A; Rigoulot, MA | 1 |
| Buckmaster, PS; Kobayashi, M; Wen, X | 1 |
| MONNIER, M; ROMANOWSKI, W | 1 |
| Clinckers, R; Ebinger, G; Lindekens, H; Lodge, D; Meurs, A; Michotte, Y; O'Neill, MJ; Smolders, I | 1 |
| Fonteles, MM; Freitas, RM; Sousa, FC; Vasconcelos, SM; Viana, GS | 1 |
| Chu, K; Jeon, D; Jeong, SW; Jung, KH; Kim, J; Kim, M; Kim, SU; Lee, SK; Lee, ST; Roh, JK; Shin, HS | 1 |
| Bolvig, T; Clausen, RP; Falch, E; Frølund, B; Hansen, SL; Krogsgaard-Larsen, P; Larsson, OM; Perregaard, J; Petersen, G; Sarup, A; Schousboe, A; Slough, S; Watson, WP; White, HS | 1 |
| Carlson, BB; Correa, M; Ishiwari, K; Mingote, S; Salamone, JD; Trevitt, JT | 1 |
| Gillessen, T; Grasshoff, C; Szinicz, L; Thiermann, H; Wagner, E | 1 |
| Houser, CR; Peng, Z | 1 |
| Avoli, M; Benini, R | 1 |
| DeLorenzo, RJ; Sun, DA | 1 |
| Buckmaster, PS; Kumar, SS | 1 |
| Brandt, C; Ebert, U; Freichel, C; Löscher, W; Potschka, H | 1 |
| Avoli, M; Baldelli, E; Biagini, G; de Guzman, P; Inaba, Y; Merlo, D; Mollinari, C | 1 |
| Choi, SY; Kang, TC; Kim, DS; Kim, JE; Kim, JS; Kwak, SE; Kwon, OS; Lee, HJ; Won, MH | 1 |
| Banuelos, C; Castañeda, MT; Colom, LV; Garrido Sanabria, ER; Hernandez, S; Perez-Cordova, MG | 1 |
| Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I | 2 |
| Bernard, C; El-Hassar, L; Esclapez, M; Ferrand, N; Milh, M; Wendling, F | 1 |
| Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS | 1 |
| Assis, MA; Fonteles, MM; Freitas, RL; Freitas, RM; Pereira, MB; Silva, RF; Takahashi, RN | 1 |
| Aronica, E; Cantore, G; Esposito, V; Eusebi, F; Fucile, S; Maiolino, F; Manfredi, M; Martinello, K; Mazzuferi, M; Miledi, R; Palma, E; Roseti, C; Simonato, M | 1 |
| Hirase, M; Honda, E; Inenaga, K; Ono, K; Wakasugi-Sato, N | 1 |
| Buckmaster, PS; Ribak, CE; Thind, KK | 1 |
| Behr, J; Fidzinski, P; Frahm, C; Knopp, A; Witte, OW | 1 |
| Chen, LW; Huang, YG; Liu, YH; Wang, L | 1 |
| Aziz, MA; El Hay Ahmed, NA; Ibrahim, KM; Khadrawy, YA; Khedr, ME; Radwan, NM | 1 |
| Choi, SY; Kang, TC; Kim, DW; Kim, JE; Kwak, SE; Kwon, OS | 1 |
| Nadler, JV; Zhan, RZ | 1 |
| Aourz, N; Clinckers, R; De Bundel, D; Meurs, A; Michotte, Y; Portelli, J; Smolders, I | 1 |
| Alcantara-Gonzalez, D; Cuellar-Herrera, M; Neri-Bazan, L; Peña, F; Rocha, L | 1 |
| Chen, S; Fujita, S; Kobayashi, M; Koshikawa, N | 1 |
| Buckmaster, PS; Phanwar, I; Thind, KK; Wen, X; Yamawaki, R; Zhang, G | 1 |
| Aourz, N; Clinckers, R; De Bundel, D; Hoyer, D; Kastellakis, A; Kiagiadaki, F; Michotte, Y; Smolders, I; Thermos, K | 1 |
| Khan, RS; Mathew, J; Paulose, CS; Peeyush Kumar, T | 1 |
| Mathew, J; Paulose, CS; Sadanandan, J; Soman, S | 1 |
| Avoli, M; Biagini, G; Bortel, A; de Guzman, P; Dubeau, F; Longo, D | 1 |
| Houser, CR; Mody, I; Wyeth, MS; Zhang, N | 1 |
| de Freitas, RM; de Oliveira Silva, F; Jordán, J; Saldanha, GB | 1 |
| Choi, HC; Kang, TC; Kim, DS; Kim, JE; Kim, YI; Song, HK | 1 |
| Paz, C; Retana-Márquez, S; Rubio, C; Rubio-Osornio, M; Verónica Custodio, ML | 1 |
| Bi, F; Chen, S; Feng, L; Li, G; Li, S; Li, Y; Long, L; Mutasem, MA; Xiao, B; Yi, F | 1 |
| Bortolatto, CF; Gai, BM; Nogueira, CW; Roehrs, JA; Souza, AC; Wilhelm, EA | 1 |
| Abraham, PM; Antony, S; Balakrishnan, S; Mathew, J; Paulose, CS | 1 |
| Guo, H; Jiang, M; Jiang, S; Liu, Y; Shu, Y; Tian, C; Wang, K; Wang, Y; Yang, M; Zhu, J | 1 |
| Aerssens, J; Aourz, N; Bortolotto, ZA; Clinckers, R; Collingridge, GL; Coppens, J; Loyens, E; Michotte, Y; Moechars, D; Portelli, J; Schallier, A; Smolders, I; Thielemans, L; Ver Donck, L; Vermoesen, K | 1 |
| Collins-Praino, LE; Kovner, R; Podurgiel, SJ; Randall, PA; Salamone, JD | 1 |
| Brito, GA; Cavalheiro, EA; da Costa, MA; da Cruz, GM; da Graça Naffah-Mazzacoratti, M; de Andrade, GM; de Barros Viana, GS; Felipe, CF; Leal, LK; Menezes, ML; Scorza, FA; Tavares, AF | 1 |
| Elgammal, FS; Ito, T; Proddutur, A; Santhakumar, V; Yu, J | 1 |
| Loyens, E; Massie, A; Michotte, Y; Schallier, A; Smolders, I; Van Liefferinge, J; Vermoesen, K | 1 |
| Kawaguchi, M; Okubo, M | 1 |
| Liu, J; Liu, Y; Tang, F | 1 |
| Cheng, JT; Huang, CC; Huang, CW; Lai, MC; Tsai, JJ; Wu, SN | 1 |
| Ebihara, K; Kobayashi, M; Koshikawa, N; Yamamoto, K | 1 |
| Cai, X; Chen, S; Chen, Y; Chen, Z; Fang, Z; Wang, Q; Yang, L; Zhou, J; Zhou, L | 1 |
| Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A | 1 |
| Binaschi, A; Falcicchia, C; Grandi, E; Magri, E; Palma, E; Roncon, P; Simonato, M; Soukupová, M; Zucchini, S | 1 |
| Filipek, B; Höfner, GC; Kowalczyk, P; Kulig, K; Mucha, M; Podkowa, A; Rapacz, A; Sałat, K; Wanner, KT | 1 |
| Kim, IS; Kim, WJ; Lee, H; Lee, IS; Park, KI; Park, SC; Shin, JE; Yun, S | 1 |
| Brooks-Kayal, AR; Carlsen, J; Cogswell, M; Cruz Del Angel, Y; Gonzalez, MI; Grabenstatter, HL; Raol, YH; Russek, SJ | 1 |
| Barati, M; Eftekhari, S; Hadjighassem, MR; Hassanzadeh, G; Hayat, P; Joghataei, MT; Mehdizadeh, H; Mehrabi, S; Mostafavi, H; Rahmanzadeh, R; Shahrokhi, A; Soleimani, M | 1 |
| Bos, IW; de Graan, PN; Hessel, EV; Mulder, SD; van der Hel, WS; van Eijsden, P; Verlinde, SA | 1 |
| Orozco-Suárez, SA; Rocha, L; Santana-Gómez, CE; Valle-Dorado, MG | 1 |
| Alcántara-González, D; Bañuelos-Cabrera, I; Besio, W; Fernández-Mas, R; Luna-Munguía, H; Magdaleno-Madrigal, V; Rocha, L; Santana-Gómez, CE | 1 |
| Binaschi, A; Falcicchia, C; Palma, E; Roncon, P; Simonato, M; Soukupova, M; Zucchini, S | 1 |
| Goodkin, HP; Sun, HY | 1 |
| Alcantara-Gonzalez, D; Banuelos-Cabrera, I; Besio, WG; Luna-Munguia, H; Magdaleno-Madrigal, V; Rocha, LL; Santana-Gomez, CE; Tamayo, M | 1 |
| Gulec Suyen, G; Isbil-Buyukcoskun, N; Kahveci, N; Ozluk, K; Sengun, E | 1 |
| Aseervatham, GS; Bose, PC; Sivasudha, T; Sundaram, S; Suryakala, U | 1 |
| Baraban, SC; Casalia, ML; Howard, MA | 1 |
| Aarão, MC; Antonio, BB; Barros, V; Bittencourt, S; de Almeida, AG; Ferrazoli, E; Janisset, NRLL; Longo, BM; Macedo, CE; Mello, LE; Miranda, MF; Mundim, M; Porcionatto, M; Rodrigues, AM; Romariz, S; Valente, MF | 1 |
| Anas, ARJ; Eguchi, M; Oishi, K; Ono, K; Oya, M; Sawada, M; Suzuki, H; Yamaguchi, S | 1 |
| Chen, Y; Fajol, A; Ren, B; Shi, S; Song, S | 1 |
| Alvarado-Franco, NL; Femat-Roldan, G; Garza-Alpirez, A; Gonzalez-Marques, C; Martinez-Ramirez, D; Olguín-Ramírez, LA | 1 |
| Chen, S; Liu, F; Liu, J; Wu, G; Xu, K; Xu, W | 1 |
| Guo, F; Li, X; Liu, N; Ma, L; Sun, T; Yu, J; Zhang, X; Zheng, P; Zhou, R | 1 |
| Aktar, M; Cho, KO; Ge, S; Goswami, S; Hsieh, J; Jarzabek, V; Lybrand, ZR; Merlock, N; Smith, C; Varma, P; Zhang, L; Zhu, J | 1 |
| Hong, GP; Kim, HJ; Kim, MH | 1 |
| Houser, CR; Huang, CS; Mody, I; Peng, Z; Sun, Y; Wallner, M; Wei, X; Zhang, N | 1 |
2 review(s) available for pilocarpine and gamma-aminobutyric acid
| Article | Year |
|---|---|
Basic mechanisms in status epilepticus: role of calcium in neuronal injury and the induction of epileptogenesis.
Topics: Animals; Calcium; Cell Death; Drug Interactions; gamma-Aminobutyric Acid; Humans; Kainic Acid; Neurons; Pilocarpine; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Time Factors | 2006 |
In vivo experimental models of epilepsy.
Topics: Aluminum Hydroxide; Animals; Bicuculline; Cobalt; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; Epilepsy, Reflex; Flurothyl; gamma-Aminobutyric Acid; Humans; Kainic Acid; Kindling, Neurologic; Muscarinic Agonists; Papio; Penicillins; Pentylenetetrazole; Pilocarpine; Tetanus Toxin; Zinc Compounds | 2010 |
122 other study(ies) available for pilocarpine and gamma-aminobutyric acid
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
The action of DL-2,4-diaminobutyric acid on the cataleptogenic effects of pilocarpine and alpha-flupenthixol in rats.
Topics: Aminobutyrates; Animals; Catalepsy; Drug Synergism; Female; Flupenthixol; gamma-Aminobutyric Acid; Humans; Pilocarpine; Rats; Thioxanthenes | 1979 |
Release of [3H]acetylcholine from rat hippocampal slices: effect of septal lesion and of graded concentrations of muscarnic agonists and antagonists.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzilates; Carbachol; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Mecamylamine; Oxotremorine; Pilocarpine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine; Septum Pellucidum | 1977 |
Oral secretion elicited by effectors of signal transduction pathways in the salivary glands of Amblyomma americanum (Acari: Ixodidae).
Topics: Animals; Diglycerides; Dopamine; Female; gamma-Aminobutyric Acid; Pilocarpine; Salivary Glands; Signal Transduction; Tetradecanoylphorbol Acetate; Theophylline; Ticks | 1992 |
Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models.
Topics: Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Isoniazid; Kainic Acid; Male; Microinjections; Muscimol; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Synaptic Transmission | 1991 |
Brain amino acid concentration changes during status epilepticus induced by lithium and pilocarpine.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus; Tissue Distribution | 1990 |
GAD-immunoreactive neurons are preserved in the hippocampus of rats with spontaneous recurrent seizures.
Topics: Animals; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Male; Neurons; Pilocarpine; Rats; Rats, Inbred Strains; Recurrence; Seizures; Status Epilepticus | 1990 |
Reduction of paired pulse inhibition in the CA1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats.
Topics: Amygdala; Animals; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Neural Inhibition; Pilocarpine; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Studies on the pharmacology of skeletal muscle in culture: specificity of receptors.
Topics: Acetylcholine; Animals; Atropine; Bungarotoxins; Carbachol; Chick Embryo; Culture Techniques; Decamethonium Compounds; Dimethylphenylpiperazinium Iodide; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Gallamine Triethiodide; gamma-Aminobutyric Acid; Histamine; Membrane Potentials; Methacholine Compounds; Muscles; Nicotine; Norepinephrine; Pilocarpine; Quaternary Ammonium Compounds; Receptors, Drug; Scopolamine; Serotonin; Succinylcholine | 1974 |
Stress-induced enhancement of suppression of [3H]GABA release from striatal slices by presynaptic autoreceptor.
Topics: Aminolevulinic Acid; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Male; Muscimol; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stress, Physiological; Tetraethylammonium Compounds | 1984 |
Effect of intrastriatal administration of cholinergic and GABAergic agonists on apomorphine-induced circling.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Drug Interactions; gamma-Aminobutyric Acid; Humans; Injections; Male; Muscimol; Parasympathomimetics; Picrotoxin; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Scopolamine; Stereotyped Behavior | 1984 |
Further evidence for a functional dorsal-ventral division of the rat striatum: GABAergic involvement in oral movements.
Topics: Animals; Apomorphine; Behavior, Animal; Benzamides; Benzazepines; Carbachol; Corpus Striatum; Dopamine; Flunitrazepam; gamma-Aminobutyric Acid; Jaw; Male; Muscimol; N-Methylscopolamine; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives | 1993 |
Effects of chronic nicotine and pilocarpine administration on neocortical neuronal density and [3H]GABA uptake in nucleus basalis lesioned rats.
Topics: Animals; Cell Count; Cerebral Cortex; gamma-Aminobutyric Acid; Ibotenic Acid; Neurons; Nicotine; Pilocarpine; Rats; Rats, Wistar; Stereoisomerism; Substantia Innominata; Time Factors; Tritium | 1993 |
GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus.
Topics: Amino Acids; Aminocaproates; Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Lithium; Male; Parietal Lobe; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Substantia Nigra; Vigabatrin | 1993 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
Long-term consequences of subtle stimuli during the first twenty-four hours of seizure-induced brain injury.
Topics: Acetates; Amines; Animals; Anticonvulsants; Appetitive Behavior; Brain Damage, Chronic; Cholinergic Fibers; Cyclohexanecarboxylic Acids; Dominance, Cerebral; Electromagnetic Fields; Gabapentin; gamma-Aminobutyric Acid; Limbic System; Lithium; Male; Maze Learning; Mental Recall; Pilocarpine; Prednisolone; Rats; Seizures | 1996 |
Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures.
Topics: Animals; Antibodies, Monoclonal; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Humans; Immunohistochemistry; In Situ Hybridization; Male; Neuronal Plasticity; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA; RNA, Messenger; Seizures | 1996 |
Changes in hippocampal circuitry after pilocarpine-induced seizures as revealed by opioid receptor distribution and activation.
Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Male; Neural Pathways; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tissue Distribution | 1997 |
Effect of pilocarpine on striatal acetylcholine release in dopamine-depleted rats.
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar | 1997 |
GABA metabolism during status epilepticus in the developing rat brain.
Topics: Age Factors; Animals; gamma-Aminobutyric Acid; Hippocampus; Lithium; Muscarinic Agonists; Parietal Lobe; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 1997 |
Hippocampal and cerebellar extracellular amino acids during pilocarpine-induced seizures in freely moving rats.
Topics: Amino Acids; Animals; Aspartic Acid; Carbamazepine; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures | 1997 |
Muscarinic modulation of striatal dopamine, glutamate, and GABA release, as measured with in vivo microdialysis.
Topics: Animals; Cholinergic Agents; Corpus Striatum; Diamines; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Parasympatholytics; Parasympathomimetics; Pilocarpine; Pirenzepine; Rats; Rats, Wistar; Substantia Nigra | 1997 |
Differential epilepsy-associated alterations in postsynaptic GABA(A) receptor function in dentate granule and CA1 neurons.
Topics: Animals; Clonazepam; Epilepsy, Temporal Lobe; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Logistic Models; Patch-Clamp Techniques; Pilocarpine; Pyridines; Rats; Receptors, GABA-A; Zinc; Zolpidem | 1997 |
NMDA receptor-mediated pilocarpine-induced seizures: characterization in freely moving rats by microdialysis.
Topics: Animals; Anticonvulsants; Atropine; Convulsants; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Lamotrigine; Male; Microdialysis; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Triazines | 1997 |
Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freel
Topics: Animals; Anticonvulsants; Cerebellum; Dopamine; Electroencephalography; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Pilocarpine; Rats; Rats, Wistar; Substantia Nigra; Vigabatrin | 1997 |
GABA(A) receptor function in epileptic human dentate granule cells: comparison to epileptic and control rat.
Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; N-Methylscopolamine; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Temporal Lobe; Zinc | 1998 |
GABAergic neurons and GABA(A)-receptors in temporal lobe epilepsy.
Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Immunoenzyme Techniques; Interneurons; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A | 1999 |
Effects of diazepam on extracellular brain neurotransmitters in pilocarpine-induced seizures in rats.
Topics: Animals; Behavior, Animal; Brain; Cerebellum; Diazepam; Dopamine; Electroencephalography; Extracellular Space; GABA Modulators; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Male; Neurotransmitter Agents; Pilocarpine; Rats; Rats, Wistar; Seizures | 1999 |
Up-regulation of GAD65 and GAD67 in remaining hippocampal GABA neurons in a model of temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; In Situ Hybridization; Isoenzymes; Male; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 1999 |
Deficit of quantal release of GABA in experimental models of temporal lobe epilepsy.
Topics: Animals; Electric Conductivity; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Hippocampus; Kainic Acid; Nerve Endings; Neural Inhibition; Pilocarpine; Pyramidal Cells; Rats; Receptors, GABA-A; Reference Values; Synapses; Synaptic Vesicles | 1999 |
Anticonvulsive activity of Albizzia lebbeck, Hibiscus rosa sinesis and Butea monosperma in experimental animals.
Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Convulsants; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Lithium; Male; Mice; Muscarinic Agonists; Pentobarbital; Pentylenetetrazole; Pilocarpine; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Serotonin; Sleep | 2000 |
The effect of CGP-40116 on pilocarpine evoked seizures in mice exposed to transient episode of brain ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Behavior, Animal; Brain; Brain Chemistry; Carotid Artery, Common; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Ischemic Preconditioning; Male; Mice; Muscarinic Agonists; Pilocarpine; Seizures | 2000 |
In vivo study of the effect of valpromide and valnoctamide in the pilocarpine rat model of focal epilepsy.
Topics: Amides; Animals; Anti-Anxiety Agents; Anticonvulsants; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar; Valproic Acid | 2000 |
2-chloro-N(6)-cyclopentyladenosine-elicited attenuation of evoked glutamate release is not sufficient to give complete protection against pilocarpine-induced seizures in rats.
Topics: Adenosine; Animals; Behavior, Animal; Dopamine; Electroencephalography; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indicators and Reagents; Male; Neurotransmitter Agents; Pilocarpine; Rats; Rats, Wistar; Seizures; Xanthines | 2001 |
Lack of effect of mossy fiber-released zinc on granule cell GABA(A) receptors in the pilocarpine model of epilepsy.
Topics: Action Potentials; Animals; Dendrites; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Models, Animal; Mossy Fibers, Hippocampal; Muscimol; Nerve Endings; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Zinc | 2001 |
Alterations of hippocampal GAbaergic system contribute to development of spontaneous recurrent seizures in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lithium; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Recurrence | 2001 |
Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy.
Topics: Acetylcholine; Action Potentials; Aggression; Animals; Behavior, Animal; Brain; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscarinic Agonists; Nerve Degeneration; Neural Pathways; Neurons; Picrotoxin; Pilocarpine; Rats; Rats, Wistar; Reaction Time; Statistics as Topic | 2002 |
Attenuating effects of melatonin on pilocarpine-induced seizures in rats.
Topics: Age Factors; Animals; Anticonvulsants; Female; gamma-Aminobutyric Acid; Melatonin; N-Methylscopolamine; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A; Seizures | 2002 |
Axon sprouting in a model of temporal lobe epilepsy creates a predominantly excitatory feedback circuit.
Topics: Animals; Atropine Derivatives; Axons; Dendrites; Disease Models, Animal; Epilepsy, Temporal Lobe; Feedback; gamma-Aminobutyric Acid; Interneurons; Lysine; Male; Mossy Fibers, Hippocampal; Pilocarpine; Rats; Rats, Sprague-Dawley; Synapses | 2002 |
Alterations of the neocortical GABAergic system in the pilocarpine model of temporal lobe epilepsy: neuronal damage and immunocytochemical changes in chronic epileptic rats.
Topics: Animals; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Neocortex; Neurons; Pilocarpine; Rats; Rats, Wistar | 2002 |
N-, alpha-, and beta-Substituted 3-Aminopropionic acids: design, syntheses and antiseizure activities.
Topics: Animals; Anticonvulsants; Binding Sites; Electroshock; gamma-Aminobutyric Acid; Glycine; Male; Models, Molecular; Pentylenetetrazole; Pilocarpine; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Toxicity Tests | 2003 |
Unaltered control of extracellular GABA-concentration through GAT-1 in the hippocampus of rats after pilocarpine-induced status epilepticus.
Topics: Animals; Disease Models, Animal; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Muscarinic Agonists; Nipecotic Acids; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Tiagabine | 2003 |
Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Aspartic Acid; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraperitoneal; Levetiracetam; Male; Microinjections; Phenobarbital; Pilocarpine; Piracetam; Rats; Rats, Sprague-Dawley; Valproic Acid | 2003 |
Long-term pregabalin treatment protects basal cortices and delays the occurrence of spontaneous seizures in the lithium-pilocarpine model in the rat.
Topics: Animals; Anticonvulsants; Astrocytes; Brain; Cell Death; Cerebral Cortex; Convulsants; Electroencephalography; Entorhinal Cortex; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hippocampus; Immunoenzyme Techniques; Lithium; Neuroprotective Agents; Parahippocampal Gyrus; Pilocarpine; Pregabalin; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2003 |
Downregulation of the alpha5 subunit of the GABA(A) receptor in the pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Down-Regulation; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Male; Muscarinic Agonists; Nerve Degeneration; Neural Inhibition; Neuronal Plasticity; Pilocarpine; Protein Subunits; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Synaptic Transmission | 2003 |
Reduced inhibition and increased output of layer II neurons in the medial entorhinal cortex in a model of temporal lobe epilepsy.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Entorhinal Cortex; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Interneurons; Isoenzymes; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2003 |
[Cerebral cholinoceptive systems--action of acetylcholine, physostigmine, pilocarpine and GABA].
Topics: Acetylcholine; Brain; gamma-Aminobutyric Acid; Humans; Nervous System Physiological Phenomena; Parasympathomimetics; Physostigmine; Pilocarpine | 1962 |
In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands.
Topics: Amino Acids; Animals; Anticonvulsants; Benzoates; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Ligands; Limbic System; Male; Microdialysis; Pilocarpine; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures | 2004 |
Pilocarpine-induced status epilepticus in rats: lipid peroxidation level, nitrite formation, GABAergic and glutamatergic receptor alterations in the hippocampus, striatum and frontal cortex.
Topics: Animals; Corpus Striatum; Frontal Lobe; gamma-Aminobutyric Acid; Hippocampus; Lipid Peroxidation; Male; Nitrites; Pilocarpine; Rats; Rats, Wistar; Receptors, Glutamate; Status Epilepticus | 2004 |
Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats.
Topics: Aggression; Animals; Animals, Newborn; Behavior, Animal; Cell Count; Cell Death; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Male; Neural Inhibition; Neurons; Parvalbumins; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Seizures; Status Epilepticus; Stem Cell Transplantation; Stem Cells; Time Factors | 2004 |
First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.
Topics: Acoustic Stimulation; Acyltransferases; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Cells, Cultured; Cloning, Molecular; Convulsants; Drug Synergism; Epilepsy; Epilepsy, Reflex; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; N-Acetylglucosaminyltransferases; Neurons; Nipecotic Acids; Pentylenetetrazole; Pilocarpine; Psychomotor Disorders; Recombinant Proteins; Seizures; Tiagabine | 2005 |
The GABA uptake inhibitor beta-alanine reduces pilocarpine-induced tremor and increases extracellular GABA in substantia nigra pars reticulata as measured by microdialysis.
Topics: Animals; beta-Alanine; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Extracellular Fluid; gamma-Aminobutyric Acid; Male; Masticatory Muscles; Microdialysis; Muscarinic Agonists; Neostriatum; Neural Pathways; Neurotransmitter Uptake Inhibitors; Parkinson Disease; Pilocarpine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tremor; Up-Regulation | 2004 |
Ketamine reduces cholinergic modulated GABA release from rat striatal slices.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ketamine; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Pirenzepine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2005 |
Temporal patterns of fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Interneurons; Male; Mice; Mice, Inbred C57BL; Neurons; Parvalbumins; Pilocarpine; Proto-Oncogene Proteins c-fos; Recurrence; Seizures; Temporal Lobe; Time Factors | 2005 |
Altered inhibition in lateral amygdala networks in a rat model of temporal lobe epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Matched-Pair Analysis; Nerve Net; Neural Inhibition; Neurons; Parahippocampal Gyrus; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2006 |
Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Cells, Cultured; Disease Models, Animal; Entorhinal Cortex; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Interneurons; Male; Neural Inhibition; Pilocarpine; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 2006 |
Acute changes in the neuronal expression of GABA and glutamate decarboxylase isoforms in the rat piriform cortex following status epilepticus.
Topics: Analysis of Variance; Animals; Cell Count; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Immunohistochemistry; In Situ Hybridization; Isoenzymes; Kainic Acid; Neurons; Olfactory Pathways; Pilocarpine; Protein Isoforms; Rats; Rats, Wistar; RNA, Messenger; Status Epilepticus | 2006 |
Subiculum network excitability is increased in a rodent model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Biomarkers; Convulsants; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; K Cl- Cotransporters; Nerve Net; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Neurons; Organ Culture Techniques; Parvalbumins; Pilocarpine; Rats; Symporters; Synapses; Synaptic Transmission; Synaptophysin | 2006 |
Differential paired-pulse responses between the CA1 region and the dentate gyrus are related to altered CLC-2 immunoreactivity in the pilocarpine-induced rat epilepsy model.
Topics: Action Potentials; Animals; Chloride Channels; CLC-2 Chloride Channels; Convulsants; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Muscarinic Agonists; Neural Inhibition; Pilocarpine; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vesicular Inhibitory Amino Acid Transport Proteins | 2006 |
Septal GABAergic neurons are selectively vulnerable to pilocarpine-induced status epilepticus and chronic spontaneous seizures.
Topics: Analysis of Variance; Animals; Cell Survival; Disease Models, Animal; Fluoresceins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Organic Chemicals; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Septum of Brain; Status Epilepticus; Time Factors | 2006 |
Substantia nigra is an anticonvulsant site of action of topiramate in the focal pilocarpine model of limbic seizures.
Topics: Animals; Anticonvulsants; Area Under Curve; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsies, Partial; Fructose; Functional Laterality; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Male; Microdialysis; Microinjections; Pilocarpine; Rats; Rats, Wistar; Seizures; Substantia Nigra; Synaptic Transmission; Topiramate | 2006 |
Cell domain-dependent changes in the glutamatergic and GABAergic drives during epileptogenesis in the rat CA1 region.
Topics: Algorithms; Animals; Dendrites; Electrodes, Implanted; Electroencephalography; Electrophysiology; Epilepsy; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Male; Muscarinic Agonists; Neurons; Pilocarpine; Pyramidal Cells; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 2007 |
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Pilocarpine; Pimozide; Rats; Seizures; Status Epilepticus | 2006 |
Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA; Receptors, Neurotransmitter; Seizures; Status Epilepticus; Vigabatrin | 2007 |
Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin.
Topics: Analysis of Variance; Animals; Behavior, Animal; Chromatography, Liquid; Disease Models, Animal; Dopamine; Electroencephalography; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Methoxyhydroxyphenylglycol; Microdialysis; Picrotoxin; Pilocarpine; Rats; Rats, Wistar; Seizures; Serotonin; Statistics, Nonparametric; Time Factors | 2008 |
GABA(A)-current rundown of temporal lobe epilepsy is associated with repetitive activation of GABA(A) "phasic" receptors.
Topics: Animals; Electrophysiology; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Male; Neurons; Okadaic Acid; Oocytes; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sensitivity and Specificity; Temporal Lobe; Xenopus; Zinc | 2007 |
Intraperitoneal injection of pilocarpine activates neurons in the circumventricular organs and hypothalamus in rats.
Topics: Animals; Biomarkers; Brain Mapping; gamma-Aminobutyric Acid; Hypothalamus; Immunohistochemistry; Injections, Intraperitoneal; Male; Muscarinic Agonists; Muscarinic Antagonists; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Pilocarpine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Salivation; Subfornical Organ; Synaptic Transmission; Thirst; Up-Regulation; Water-Electrolyte Balance | 2008 |
Synaptic input to dentate granule cell basal dendrites in a rat model of temporal lobe epilepsy.
Topics: Animals; Cell Shape; Convulsants; Dendrites; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Male; Microscopy, Electron; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptic Transmission | 2008 |
Loss of GABAergic neurons in the subiculum and its functional implications in temporal lobe epilepsy.
Topics: Animals; Biomarkers; Dendrites; Electroencephalography; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; In Situ Hybridization; Interneurons; Patch-Clamp Techniques; Pilocarpine; Presynaptic Terminals; Pyramidal Cells; Rats; Staining and Labeling | 2008 |
Time-course of neuronal death in the mouse pilocarpine model of chronic epilepsy using Fluoro-Jade C staining.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cerebral Cortex; Chronic Disease; Convulsants; Disease Models, Animal; Epilepsy; Fluoresceins; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Male; Mice; Nerve Degeneration; Neural Inhibition; Neurons; Organic Chemicals; Pilocarpine; Staining and Labeling; Time Factors | 2008 |
Effect of infrared laser irradiation on amino acid neurotransmitters in an epileptic animal model induced by pilocarpine.
Topics: Alanine Transaminase; Amino Acids; Analysis of Variance; Animals; Aspartate Aminotransferases; Aspartic Acid; Cerebral Cortex; Chromatography, High Pressure Liquid; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Lasers, Semiconductor; Male; Models, Animal; Neurotransmitter Agents; Pilocarpine; Rats; Taurine | 2009 |
Enhanced pyridoxal 5'-phosphate synthetic enzyme immunoreactivities do not contribute to GABAergic inhibition in the rat hippocampus following pilocarpine-induced status epilepticus.
Topics: Action Potentials; Animals; Cell Death; Dentate Gyrus; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hippocampus; Linear Models; Male; Microtubule-Associated Proteins; Neural Inhibition; Pilocarpine; Pyramidal Cells; Pyridoxal Kinase; Pyridoxaminephosphate Oxidase; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors | 2009 |
Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus.
Topics: Action Potentials; Animals; Extracellular Space; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus | 2009 |
Intrastrain differences in seizure susceptibility, pharmacological response and basal neurochemistry of Wistar rats.
Topics: Analysis of Variance; Anesthetics, Dissociative; Animals; Biogenic Monoamines; Body Weight; Brain; Brain Chemistry; Chi-Square Distribution; Chromatography, Reverse-Phase; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Ketamine; Male; Microdialysis; Pilocarpine; Rats; Rats, Wistar; Retrospective Studies; Seizures; Species Specificity | 2009 |
Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Lithium Chloride; Male; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Synaptic Transmission | 2010 |
Pilocarpine-induced status epilepticus causes acute interneuron loss and hyper-excitatory propagation in rat insular cortex.
Topics: Animals; Biomarkers; Cell Count; Cerebral Cortex; Convulsants; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; Fluoresceins; Fluorescent Dyes; Frontal Lobe; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Nerve Degeneration; Neural Inhibition; Neural Pathways; Neurons; Organic Chemicals; Parvalbumins; Pilocarpine; Rats; Rats, Sprague-Dawley; Somatostatin; Staining and Labeling; Status Epilepticus; Synaptic Transmission | 2010 |
Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy.
Topics: Animals; Cell Count; Convulsants; Dendritic Spines; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Interneurons; Microscopy, Immunoelectron; Nerve Degeneration; Neural Inhibition; Neurogenesis; Neuronal Plasticity; Neurons; Pilocarpine; Rats; Recovery of Function; Status Epilepticus; Synapses | 2010 |
Hippocampal sst(1) receptors are autoreceptors and do not affect seizures in rats.
Topics: Animals; Autoreceptors; Chromatography, Liquid; gamma-Aminobutyric Acid; Hippocampus; Male; Microdialysis; Microinjections; Muscarinic Agonists; Pilocarpine; Piperazines; Quinolines; Rats; Rats, Wistar; Receptors, Somatostatin; Seizures; Somatostatin | 2010 |
Behavioral deficit and decreased GABA receptor functional regulation in the cerebellum of epileptic rats: effect of Bacopa monnieri and bacoside A.
Topics: Animals; Anticonvulsants; Behavioral Symptoms; Bicuculline; Carbamazepine; Cerebellum; Disease Models, Animal; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Phytotherapy; Pilocarpine; Plant Preparations; Protein Binding; Rats; Rats, Wistar; Receptors, GABA; Saponins; Triterpenes; Tritium | 2010 |
Decreased GABA receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of Bacopa monnieri and bacoside-A.
Topics: Animals; Anticonvulsants; Bacopa; Basal Ganglia; Behavior, Animal; Bicuculline; Binding, Competitive; Carbamazepine; Disease Models, Animal; Down-Regulation; GABA Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A; Recognition, Psychology; RNA, Messenger; Saponins; Status Epilepticus; Triterpenes | 2010 |
Selective changes in inhibition as determinants for limited hyperexcitability in the insular cortex of epileptic rats.
Topics: Action Potentials; Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Interneurons; Male; Muscarinic Agonists; Neural Inhibition; Neuropeptide Y; Parvalbumins; Pilocarpine; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Temporal Lobe | 2010 |
Selective reduction of cholecystokinin-positive basket cell innervation in a model of temporal lobe epilepsy.
Topics: Animals; CA1 Region, Hippocampal; Cholecystokinin; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Mice; Neural Pathways; Neurons; Parvalbumins; Pilocarpine; Presynaptic Terminals; Pyramidal Cells; Receptor, Cannabinoid, CB1; Status Epilepticus | 2010 |
Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dialysis; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Survival Analysis; Thioctic Acid | 2011 |
Effects of selective serotonin reuptake inhibitors on GABAergic inhibition in the hippocampus of normal and pilocarpine induced epileptic rats.
Topics: Analysis of Variance; Animals; Citalopram; Electroencephalography; Epilepsy; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition; Neurons; Paroxetine; Pilocarpine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vesicular Inhibitory Amino Acid Transport Proteins | 2010 |
Selective loss and axonal sprouting of GABAergic interneurons in the sclerotic hippocampus induced by LiCl-pilocarpine.
Topics: Animals; Axons; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lithium Chloride; Male; Nerve Degeneration; Neuropeptide Y; Parvalbumins; Pilocarpine; Rats; Rats, Sprague-Dawley; Sclerosis; Somatostatin; Status Epilepticus | 2011 |
Involvement of GABAergic and glutamatergic systems in the anticonvulsant activity of 3-alkynyl selenophene in 21 day-old rats.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Excitatory Amino Acid Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Organoselenium Compounds; Pilocarpine; Rats; Rats, Wistar; Seizures | 2012 |
Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A.
Topics: Animals; Bacopa; Cerebral Cortex; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Maze Learning; Pilocarpine; Plant Extracts; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Saponins; Triterpenes | 2012 |
Enhancement of asynchronous release from fast-spiking interneuron in human and rat epileptic neocortex.
Topics: Adolescent; Adult; Aged; Animals; Calcium; Child; Child, Preschool; Electrophysiological Phenomena; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Interneurons; Male; Middle Aged; Neocortex; Neural Inhibition; Patch-Clamp Techniques; Pilocarpine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Young Adult | 2012 |
Inactivation of the constitutively active ghrelin receptor attenuates limbic seizure activity in rodents.
Topics: Analysis of Variance; Animals; Anticonvulsants; Calcium; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Ghrelin; Green Fluorescent Proteins; HEK293 Cells; Hippocampus; Humans; In Vitro Techniques; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Muscarinic Agonists; Neurons; Patch-Clamp Techniques; Pilocarpine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Ghrelin; Seizures; Severity of Illness Index; Species Specificity; Transfection | 2012 |
Extracellular GABA in globus pallidus increases during the induction of oral tremor by haloperidol but not by muscarinic receptor stimulation.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Jaw; Male; Movement; Muscarinic Agonists; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tremor | 2012 |
Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms.
Topics: Alkaloids; Amino Acids; Animals; Anticonvulsants; Antioxidants; Atropine; Benzodioxoles; Biogenic Monoamines; Brain; Diazepam; Disease Models, Animal; Epilepsy; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Memantine; Mice; Nimodipine; Nitrites; Pilocarpine; Piperidines; Polyunsaturated Alkamides; Seizures; Tumor Necrosis Factor-alpha | 2013 |
Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells.
Topics: Action Potentials; Animals; Dentate Gyrus; GABA Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Homeostasis; Interneurons; Male; Membrane Potentials; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A; Status Epilepticus | 2013 |
L-Theanine intake increases threshold for limbic seizures but decreases threshold for generalized seizures.
Topics: Animals; Disease Models, Animal; GABA Agents; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred Strains; Microdialysis; Pentylenetetrazole; Pilocarpine; Seizures; Tea | 2013 |
Rat submandibular gland perfusion method for clarifying inhibitory regulation of GABAA receptor.
Topics: Animals; Carbachol; Cyclohexanecarboxylic Acids; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Perfusion; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A; Salivation; Submandibular Gland | 2013 |
[Survival of calbindin, calretinin and parvalbumin positive neurons in mouse hippocampal CA area at chronic stage of pilocarpine-induced epilepsy].
Topics: Animals; Calbindin 2; Calbindins; Cell Survival; Chronic Disease; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Neurons; Parvalbumins; Pilocarpine | 2013 |
Pregabalin attenuates excitotoxicity in diabetes.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Blood Glucose; Cell Line; Diabetic Neuropathies; Disease Models, Animal; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glyburide; Hippocampus; KATP Channels; Male; Neurons; Pilocarpine; Potassium Channels, Inwardly Rectifying; Pregabalin; Rats; Seizures; Streptozocin | 2013 |
Reciprocal regulation of inhibitory synaptic transmission by nicotinic and muscarinic receptors in rat nucleus accumbens shell.
Topics: Acetylcholine; Animals; Animals, Genetically Modified; Atropine; Carbachol; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Interneurons; Neurons; Nicotine; Nucleus Accumbens; Pilocarpine; Presynaptic Terminals; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Synaptic Transmission | 2013 |
STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy.
Topics: Animals; Behavior, Animal; Cells, Cultured; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Inbred BALB C; Neuronal Plasticity; Neurons; Oxygen; Pilocarpine; Protein Binding; Protein Serine-Threonine Kinases; Signal Transduction; Sodium-Potassium-Chloride Symporters; Status Epilepticus | 2013 |
Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus.
Topics: Amines; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Electroencephalography; Gabapentin; gamma-Aminobutyric Acid; Gliosis; Glutamic Acid; Hippocampus; Humans; Male; Nestin; Neuroglia; Neurons; Pilocarpine; Rats; Seizures; Status Epilepticus | 2013 |
Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Calcium; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Microdialysis; Muscarinic Agonists; Neurons; Parvalbumins; Pilocarpine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Somatostatin; Tetrodotoxin; Time Factors; Video Recording | 2014 |
Synthesis, biological evaluation and structure-activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides.
Topics: Analgesics; Animals; Anticonvulsants; Antidepressive Agents; Chemistry Techniques, Synthetic; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Male; Mice; Motor Activity; Pentylenetetrazole; Pilocarpine; Rotarod Performance Test; Seizures; Structure-Activity Relationship | 2014 |
Human fetal brain-derived neural stem/progenitor cells grafted into the adult epileptic brain restrain seizures in rat models of temporal lobe epilepsy.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain; Cell Differentiation; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy, Temporal Lobe; Fetus; gamma-Aminobutyric Acid; Glial Cell Line-Derived Neurotrophic Factor; Humans; Mossy Fibers, Hippocampal; Neural Stem Cells; Pilocarpine; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Treatment Outcome | 2014 |
Effect of spontaneous seizures on GABAA receptor α4 subunit expression in an animal model of temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Pilocarpine; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures | 2014 |
BDNF modifies hippocampal KCC2 and NKCC1 expression in a temporal lobe epilepsy model.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; K Cl- Cotransporters; Male; Neurons; Pilocarpine; Rats, Wistar; Solute Carrier Family 12, Member 2; Symporters | 2014 |
Persistent reduction of hippocampal glutamine synthetase expression after status epilepticus in immature rats.
Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Hippocampus; Immunohistochemistry; Lithium; Male; Neurons; Parvalbumins; Pilocarpine; Rats, Wistar; Seizures; Status Epilepticus; Vesicular Glutamate Transport Protein 1 | 2014 |
The mast cell stabilizer sodium cromoglycate reduces histamine release and status epilepticus-induced neuronal damage in the rat hippocampus.
Topics: Analysis of Variance; Animals; Anti-Asthmatic Agents; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Cromolyn Sodium; Disease Models, Animal; Electroencephalography; Fluoresceins; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Histamine; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2015 |
Transcranial focal electrical stimulation reduces the convulsive expression and amino acid release in the hippocampus during pilocarpine-induced status epilepticus in rats.
Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Pilocarpine; Rats; Status Epilepticus; Transcranial Direct Current Stimulation | 2015 |
Increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats.
Topics: Animals; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Pilocarpine; Rats; Rats, Sprague-Dawley; Scopolamine; Signal Transduction | 2015 |
The pervasive reduction of GABA-mediated synaptic inhibition of principal neurons in the hippocampus during status epilepticus.
Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Lithium Chloride; Male; Miniature Postsynaptic Potentials; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats, Sprague-Dawley; Status Epilepticus; Time; Tissue Culture Techniques | 2016 |
Transcranial focal electrical stimulation reduces seizure activity and hippocampal glutamate release during status epilepticus.
Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Pilocarpine; Rats; Status Epilepticus; Transcranial Direct Current Stimulation | 2015 |
Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amines; Animals; Behavior, Animal; Carbamazepine; Cognition; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lithium; Male; Maze Learning; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2016 |
Expression pattern of NMDA receptors reveals antiepileptic potential of apigenin 8-C-glucoside and chlorogenic acid in pilocarpine induced epileptic mice.
Topics: Animals; Anticonvulsants; Antioxidants; Apigenin; Behavior, Animal; Chlorogenic Acid; Epilepsy; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Glutathione; Hippocampus; Male; Mice; Neuroprotective Agents; Nitric Oxide; Pilocarpine; Receptors, N-Methyl-D-Aspartate; Thiobarbituric Acid Reactive Substances | 2016 |
Persistent seizure control in epileptic mice transplanted with gamma-aminobutyric acid progenitors.
Topics: Animals; Cell Differentiation; Convulsants; Disease Models, Animal; Embryo, Mammalian; Epilepsy; Exploratory Behavior; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Interneurons; Male; Median Eminence; Mice; Mice, Transgenic; Nuclear Proteins; Pilocarpine; Scopolamine; Stem Cell Transplantation; Stem Cells; Thyroid Nuclear Factor 1; Transcription Factors | 2017 |
Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy.
Topics: Action Potentials; Animals; Autonomic Nervous System; Biperiden; Chronic Disease; Cytokines; Disease Models, Animal; Disease Progression; Epilepsy; Exploratory Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Maze Learning; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Rats; Rats, Wistar | 2017 |
LC-MS/MS imaging with thermal film-based laser microdissection.
Topics: Acetylcholine; Animals; Choline; Chromatography, Liquid; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Laser Capture Microdissection; Mice, Inbred C57BL; Neurotransmitter Agents; Pilocarpine; Tandem Mass Spectrometry | 2018 |
Anticonvulsive effects of protodioscin against pilocarpine-induced epilepsy.
Topics: Animals; Anticonvulsants; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Biomarkers; Caspase 3; Corpus Striatum; Diosgenin; Disease Models, Animal; Down-Regulation; Epilepsy; gamma-Aminobutyric Acid; Humans; Male; Mice; Pilocarpine; Proto-Oncogene Proteins c-bcl-2; Saponins; Up-Regulation | 2018 |
Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome.
Topics: Aged; Amines; Anticonvulsants; Athetosis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxychloroquine; Movement Disorders; Muscarinic Agonists; Pilocarpine; Sjogren's Syndrome | 2018 |
Transplanting GABAergic Neurons Differentiated from Neural Stem Cells into Hippocampus Inhibits Seizures and Epileptiform Discharges in Pilocarpine-Induced Temporal Lobe Epilepsy Model.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Drug Resistant Epilepsy; Electroencephalography; Epilepsy, Temporal Lobe; GABAergic Neurons; gamma-Aminobutyric Acid; Hippocampus; Male; Muscarinic Agonists; Neural Stem Cells; Pilocarpine; Rats; Seizures | 2019 |
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Iridoids; Mice; Pilocarpine; Seizures | 2019 |
A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy.
Topics: Animals; Calcium; Clozapine; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Hippocampus; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Neurons; Pilocarpine; Retroviridae; Seizures | 2021 |
Sex-related Differences in Glial Fibrillary Acidic Protein-positive GABA Regulate Neuropathology Following Pilocarpine-induced Status Epilepticus.
Topics: Animals; Female; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hippocampus; Male; Mice; Pilocarpine; Status Epilepticus | 2021 |
Virally-induced expression of GABA
Topics: Animals; Dentate Gyrus; Epilepsy; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Neurosteroids; Pilocarpine; Receptors, GABA-A | 2022 |