pilocarpine has been researched along with dizocilpine maleate in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.56) | 18.7374 |
| 1990's | 19 (48.72) | 18.2507 |
| 2000's | 11 (28.21) | 29.6817 |
| 2010's | 7 (17.95) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, ML; Hornykiewicz, O; Hörtnagl, H; Reither, H | 1 |
| Labruyere, J; Olney, JW; Price, MT; Sesma, MA; Wang, G; Wozniak, DF | 1 |
| Treiman, DM; Walton, NY | 1 |
| Jope, RS; Ormandy, GC; Snead, OC | 1 |
| Rubinstein, BK; Treiman, DM; Walton, NY | 1 |
| Starr, BS; Starr, MS | 3 |
| Jope, RS; Williams, MB | 1 |
| Beilharz, E; Dragunow, M; Gluckman, P; Hughes, P; Lawlor, P; MacGibbon, G; Singleton, K; Sirimanne, E; Young, D | 1 |
| Castrén, E; Cooper, J; da Penha Berzaghi, M; Lindholm, D; Sofroniew, M; Thoenen, H; Zafra, F | 1 |
| Dragunow, M; Hughes, P; Young, D | 1 |
| George, B; Kulkarni, SK | 1 |
| Choi, BJ; Chou, JY; Kim, CY; Kim, SK; Lee, KH; Lee, MG | 1 |
| Labuz, D; Lasón, W; Machelska, H; Przewłocka, B; Przewłocki, R; Turchan, J | 1 |
| DeLorenzo, RJ; Rice, AC | 2 |
| George, B; Kulkarni, SK; Mathur, R | 1 |
| Corso, TD; Dikranian, K; Fix, AS; Ishimaru, MJ; Nardi, A; Olney, JW; Tenkova, T; Wozniak, DF | 1 |
| DeLorenzo, RJ; Jafari, N; Morris, TA; Rice, AC; Vasconcelos, O | 1 |
| Churn, SB; DeLorenzo, RJ; Kochan, LD | 1 |
| Liu, H; Mazarati, AM; Sankar, R; Shin, DH; Wasterlain, CG | 1 |
| Churn, SB; Delorenzo, RJ; Kurz, JE; Parsons, JT; Rana, A; Sheets, D | 1 |
| Armellin, M; Bregola, G; Cattaneo, A; Giulianini, PG; Paradiso, B; Simonato, M; Steward, O; Tongiorgi, E; Zucchini, S | 1 |
| Gillessen, T; Grasshoff, C; Szinicz, L; Thiermann, H; Wagner, E | 1 |
| Allen, S; Archie, M; Auvin, S; Niquet, J; Sankar, R; Seo, DW; Wasterlain, CG | 1 |
| Gröticke, I; Hoffmann, K; Löscher, W | 1 |
| Chen, PM; Lee, WL; Tang, FR; Tang, YC; Tsai, MC | 1 |
| Azzam, D; Dbaibo, G; El Dada, S; El Hokayem, J; El Sabban, M; Kobeissi, M; Koubeissi, M; Kurdi, R; Mikati, MA; Rahmeh, A; Rizk, E; Usta, J; Zeinieh, M | 1 |
| Bankstahl, JP; Bethmann, K; Hoffmann, K; Löscher, W | 1 |
| Bortolatto, CF; Jesse, CR; Nogueira, CW; Savegnago, L; Wilhelm, EA | 1 |
| Carter, DS; DeLorenzo, RJ; Deshpande, LS; Nagarkatti, N | 1 |
| Carter, DS; DeLorenzo, RJ; Deshpande, LS; Rafiq, A; Sombati, S | 1 |
| Guan, Y; Hao, Y; Hong, Z; Wu, X; Xu, L | 1 |
| Di Maio, R; Greenamyre, JT; Hu, X; Mastroberardino, PG; Montero, LM | 1 |
| Fan, C; Fei, Z; Han, R; Kai, W; Liu, W; Long, Q; Luo, Q; Qiu, B; Wang, A; Wang, P; Wang, Z; Xin, W | 1 |
| Alsharafi, WA; Li, J; Xiao, B | 1 |
| Joshi, S; Kapur, J; Rajasekaran, K; Williamson, J | 1 |
| Fujiki, M; Kamida, T; Momii, Y; Onishi, K; Sugita, K | 1 |
39 other study(ies) available for pilocarpine and dizocilpine maleate
| Article | Year |
|---|---|
Cholinergic deficit induced by ethylcholine aziridinium (AF64A) in rat hippocampus: effect on glutamatergic systems.
Topics: Animals; Aziridines; Choline; Choline O-Acetyltransferase; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Male; Neuromuscular Blocking Agents; Parasympathetic Nervous System; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Toxins, Biological | 1991 |
NMDA antagonist neurotoxicity: mechanism and prevention.
Topics: Animals; Barbiturates; Chick Embryo; Dizocilpine Maleate; Neurotoxins; Parasympatholytics; Pilocarpine; Rats; Receptors, N-Methyl-D-Aspartate; Scopolamine; Vacuoles | 1991 |
Motor and electroencephalographic response of refractory experimental status epilepticus in rats to treatment with MK-801, diazepam, or MK-801 plus diazepam.
Topics: Animals; Behavior, Animal; Diazepam; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus | 1991 |
Anticonvulsant actions of MK-801 on the lithium-pilocarpine model of status epilepticus in rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Hippocampus; Lithium; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Status Epilepticus | 1989 |
Cardiac hypertrophy secondary to status epilepticus in the rat.
Topics: Animals; Body Weight; Cardiomegaly; Diazepam; Dizocilpine Maleate; Electroencephalography; Lithium Chloride; Male; Myocardium; Organ Size; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1995 |
The new competitive NMDA receptor antagonist CGP 40116 inhibits pilocarpine-induced limbic motor seizures and unconditioned motor behaviour in the mouse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Grooming; Limbic System; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; Pilocarpine; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Glutamate-dopamine interactions in the production of pilocarpine motor seizures in the mouse.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Pilocarpine; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Distinctive rat brain immediate early gene responses to seizures induced by lithium plus pilocarpine.
Topics: Animals; Cerebral Cortex; Diazepam; Dizocilpine Maleate; Hippocampus; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Transcription, Genetic | 1994 |
Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury?
Topics: Animals; Apoptosis; Brain Ischemia; Dizocilpine Maleate; Genes, fos; Genes, jun; Haloperidol; Hypoxia, Brain; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Transcription, Genetic | 1993 |
Paradoxical facilitation of pilocarpine-induced seizures in the mouse by MK-801 and the nitric oxide synthesis inhibitor L-NAME.
Topics: Animals; Arginine; Dizocilpine Maleate; Drug Synergism; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pilocarpine; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat hippocampus.
Topics: Aging; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cerebral Ventricles; Dizocilpine Maleate; Gene Expression; Hippocampus; In Situ Hybridization; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotrophin 3; Pilocarpine; Pyramidal Tracts; Rats; Rats, Wistar; RNA Probes; RNA, Messenger; Scopolamine; Transcription, Genetic | 1993 |
MK-801 sensitizes rats to pilocarpine induced limbic seizures and status epilepticus.
Topics: Animals; Atropine; Diazepam; Dizocilpine Maleate; Drug Synergism; Electroencephalography; Limbic System; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus | 1993 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
MK-801 augments pilocarpine-induced electrographic seizure but protects against brain damage in rats.
Topics: Animals; Brain Damage, Chronic; Dizocilpine Maleate; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures | 1997 |
Effects of pilocarpine and kainate-induced seizures on N-methyl-D-aspartate receptor gene expression in the rat hippocampus.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Hippocampus; Kainic Acid; Male; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures | 1997 |
NMDA receptor activation during status epilepticus is required for the development of epilepsy.
Topics: Animals; Cell Count; Dizocilpine Maleate; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; Male; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Status Epilepticus; Time Factors | 1998 |
Development of self-sustaining limbic status epilepticus by continuous ventral hippocampal stimulation followed by low dose pilocarpine in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Hippocampus; Limbic System; Lithium; Male; Neuroprotective Agents; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Stereotyped Behavior | 1998 |
Disseminated corticolimbic neuronal degeneration induced in rat brain by MK-801: potential relevance to Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cerebral Cortex; Dizocilpine Maleate; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Limbic System; Male; Nerve Degeneration; Pilocarpine; Rats; Rats, Sprague-Dawley; Sex Characteristics; Time Factors | 1998 |
N-methyl-D-aspartate receptor activation regulates refractoriness of status epilepticus to diazepam.
Topics: Animals; Anticonvulsants; Diazepam; Dizocilpine Maleate; Drug Resistance; Electroencephalography; Excitatory Amino Acid Antagonists; Muscarinic Agonists; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 1999 |
Persistent increased DNA-binding and expression of serum response factor occur with epilepsy-associated long-term plasticity changes.
Topics: Animals; Brain; Cell Nucleus; Cerebellum; Cerebral Cortex; Dizocilpine Maleate; DNA-Binding Proteins; Electroshock; Gene Expression Regulation; Hippocampus; Humans; Male; Neuronal Plasticity; Nuclear Proteins; Oligodeoxyribonucleotides; Organ Specificity; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Serum Response Factor; Status Epilepticus; Transcription Factors | 1999 |
Chronic inhibition of Ca(2+)/calmodulin kinase II activity in the pilocarpine model of epilepsy.
Topics: Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Intercellular Signaling Peptides and Proteins; Isoenzymes; Male; Okadaic Acid; Peptides; Phosphoric Monoester Hydrolases; Phosphorylation; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Secondary Prevention; Seizures; Status Epilepticus; Time Factors | 2000 |
Patterns of status epilepticus-induced substance P expression during development.
Topics: Age Factors; Animals; Dizocilpine Maleate; Female; Hippocampus; Lithium Chloride; Male; Neural Pathways; Neurons; Pilocarpine; Protein Precursors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Substance P; Tachykinins | 2000 |
A significant increase in both basal and maximal calcineurin activity in the rat pilocarpine model of status epilepticus.
Topics: Animals; Brain; Calcineurin; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Hippocampus; Kinetics; Male; Nitrophenols; Organ Specificity; Organophosphorus Compounds; Pilocarpine; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Substrate Specificity | 2001 |
Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis.
Topics: Animals; Biological Transport; Brain-Derived Neurotrophic Factor; Cell Compartmentation; Convulsants; Dendrites; Dizocilpine Maleate; Electroshock; Epilepsy; Hippocampus; Kainic Acid; Kindling, Neurologic; Male; Pilocarpine; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures; Status Epilepticus; Synapses | 2004 |
Ketamine reduces cholinergic modulated GABA release from rat striatal slices.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ketamine; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Pirenzepine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2005 |
Status epilepticus triggers caspase-3 activation and necrosis in the immature rat brain.
Topics: Animals; Animals, Newborn; Autophagy; Brain; Caspase 3; Cell Death; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Lithium Chloride; Male; Microscopy, Electron; Necrosis; Neurons; Pilocarpine; Pyramidal Cells; Rats; Rats, Wistar; Status Epilepticus | 2007 |
Behavioral alterations in the pilocarpine model of temporal lobe epilepsy in mice.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Hindlimb Suspension; Hippocampus; Maze Learning; Mice; Neuronal Plasticity; Pilocarpine; Psychomotor Performance; Time Factors | 2007 |
Two-methyl-6-phenylethynyl-pyridine (MPEP), a metabotropic glutamate receptor 5 antagonist, with low doses of MK801 and diazepam: a novel approach for controlling status epilepticus.
Topics: Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Mice; Oxazines; Pilocarpine; Pyridines; Status Epilepticus | 2007 |
Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms.
Topics: Animals; Cell Death; Ceramides; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Humans; In Situ Nick-End Labeling; Kainic Acid; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 2008 |
Glutamate is critically involved in seizure-induced overexpression of P-glycoprotein in the brain.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Chemistry; Capillaries; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Image Processing, Computer-Assisted; Immunohistochemistry; Muscarinic Agonists; Nerve Degeneration; Pilocarpine; Quinolines; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2008 |
Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures.
Topics: Animals; Anticonvulsants; Antioxidants; Brain; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Organoselenium Compounds; Pentylenetetrazole; Pilocarpine; Quinoxalines; Rats; Rats, Wistar; Seizures; Time Factors; Treatment Outcome | 2009 |
Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Dantrolene; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; Muscarinic Agonists; Muscle Relaxants, Central; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2010 |
Characterization of spontaneous recurrent epileptiform discharges in hippocampal-entorhinal cortical slices prepared from chronic epileptic animals.
Topics: Action Potentials; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Lysine; Neural Pathways; Neurons; Patch-Clamp Techniques; Pilocarpine | 2011 |
MK-801 prevents overexpression of multidrug resistance protein 2 after status epilepticus.
Topics: Analysis of Variance; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Brain Waves; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electroencephalography; Female; Gene Expression Regulation; Hippocampus; Lithium Chloride; Muscarinic Agonists; Neuroprotective Agents; Pilocarpine; Rats; Rats, Wistar; RNA, Messenger; Status Epilepticus; Time Factors; von Willebrand Factor | 2012 |
Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis.
Topics: Acetylcysteine; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Male; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Pilocarpine; Piperidines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Compounds | 2013 |
Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis.
Topics: Animals; Apoptosis; Convulsants; Dizocilpine Maleate; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia-Inducible Factor 1, alpha Subunit; Lithium Chloride; Male; Pilocarpine; Rats; Rats, Sprague-Dawley | 2014 |
MicroRNA-139-5p negatively regulates NR2A-containing NMDA receptor in the rat pilocarpine model and patients with temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Hippocampus; Humans; Male; MicroRNAs; Muscarinic Agonists; Oligonucleotide Array Sequence Analysis; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric | 2016 |
Neurosteroid-sensitive δ-GABA
Topics: Animals; Blotting, Western; Dentate Gyrus; Disease Models, Animal; Dizocilpine Maleate; Down-Regulation; Electroencephalography; Epilepsy, Temporal Lobe; Female; Finasteride; Hippocampus; Lithium Compounds; Male; Neuronal Plasticity; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Video Recording | 2017 |
Anticonvulsant and antioxidant effects of lamotrigine on pilocarpine-induced status epilepticus in mice.
Topics: Animals; Anticonvulsants; Antioxidants; Dizocilpine Maleate; Glutathione; Hippocampus; Lamotrigine; Male; Mice; Mice, Inbred C57BL; Pilocarpine; Rats; Status Epilepticus | 2023 |