Page last updated: 2024-08-17

pilocarpine and clonidine

pilocarpine has been researched along with clonidine in 47 studies

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (46.81)	18.7374
1990's	13 (27.66)	18.2507
2000's	9 (19.15)	29.6817
2010's	3 (6.38)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Botwinick, CY; Freedman, LS; Gutwein, BM; Quartermain, D	1
Harrison, R; Kaufmann, CS	1
Gaul, SL; Sweet, CS	1
Ofner, S; Samples, JR; van Buskirk, EM	1
Bodnar, RJ; Kiefel, JM	1
Lee, C; McKenna, KE; Wang, JM	1
Lothman, EW; Stringer, JL	1
Alcaraz-Michelli, V; Fernandez-Bahamonde, JL	1
Hollingsworth, PJ; Smith, CB	1
Robin, AL	1
Booth, TF	1
Ahrens, FA; Panichkriangkrai, W	1
Bhargava, KP; Gurtu, S; Pant, KK; Sharma, DK; Sinha, JN	1
Jahnke, R; Thumm, HW	2
Lackner, F	1
Edelhauser, E; Nemetz, U	1
Ciracì, G; Giummarra, C; Reibaldi, A	1
Hopkins, GA	1
Brozek, B; Krejcí, L	1
Laher, IE; McNeill, JH; Rodgers, RL; Tenner, TE	1
Becker, H; Kaskel, D; Rudolf, H	1
Gross, G; Täumer, R	1
Becker, B; Goldberg, I; Gordon, M; Hodapp, E; Kass, MA; Kolker, AE	1
Fregly, MJ; Greenleaf, JE; Kelleher, DL	1
Junker, C; Junker, H	1
Cunliffe, IA; Dapling, RB; Longstaff, S	1
Asier Garro, M; García-Sevilla, JA; Giralt, MT; Menargues, A; Miralles, A; Obach, R; Olmos, G; Pineda, J; Ugedo, L	1
Agarwal, HC; Rajashekar, YL; Sihota, R	1
Alçelik, T; Caglar, Y; Elibol, O; Yüksel, N	1
García-Sevilla, JA; Pineda, J; Ugedo, L	1
Brubaker, R; Dinslage, S; McLaren, J	1
Gangnon, R; Heatley, GA; Kaufman, PL; Lewis, R; Perkins, TW	1
Birt, CM; Chung, HS; Glover, BK; Hughes, BA; Juzych, MS; Kim, C; Ren, J; Shin, DH	1
Cheung, J; Sharma, S	1
Chua, JK; Lai, JS; Lam, DS; Tham, CC	1
Molina Martínez, IT	1
Agarwal, H; Rajashekhar, YL; Sihota, R; Venkatesh, P	1
Alias, E; Díaz, S; Fernández, FJ; Ferrer, C; González, I; Honrubia, FM; Pérez-Iñigo, MA	1
Kim, HY; Kwon, HJ	1
Musch, DC; Weizer, JS; Zhang, L	1

Reviews

4 review(s) available for pilocarpine and clonidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug treatment of glaucoma. American journal of optometry and physiological optics, 1984, Volume: 61, Issue:12 Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Bromocriptine; Clonidine; Dronabinol; Epinephrine; Glaucoma; Humans; Labetalol; Miotics; Nadolol; Parasympathomimetics; Pilocarpine; Propanolamines; Sympathomimetics; Timolol	1984
[Report on the application of chibro-timoptol after one year's use in ophthalmological practice (author's transl)]. Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 177, Issue:3 Topics: Acetazolamide; Clonidine; Glaucoma; Humans; Pilocarpine; Propanolamines; Timolol	1980
Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty. The Cochrane database of systematic reviews, 2017, 02-23, Volume: 2 Topics: Adrenergic alpha-2 Receptor Agonists; Antihypertensive Agents; Brimonidine Tartrate; Clonidine; Conjunctiva; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Pilocarpine; Postoperative Complications; Randomized Controlled Trials as Topic; Trabeculectomy	2017

Trials

10 trial(s) available for pilocarpine and clonidine

Article	Year
Clonidine. Effects of a topically administered solution on intraocular pressure and blood pressure in open-angle glaucoma. Archives of ophthalmology (Chicago, Ill. : 1960), 1977, Volume: 95, Issue:8 Topics: Administration, Topical; Blood Pressure; Clonidine; Glaucoma; Humans; Intraocular Pressure; Pilocarpine	1977
The combined use of apraclonidine and pilocarpine during laser iridotomy in a Hispanic population. Annals of ophthalmology, 1990, Volume: 22, Issue:12 Topics: Aged; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Hispanic or Latino; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Pilocarpine; Postoperative Complications; Premedication; Prospective Studies	1990
[Influence of clonidine on intraocular pressure and pupillary diameter]. Klinische Monatsblatter fur Augenheilkunde, 1972, Volume: 161, Issue:1 Topics: Analysis of Variance; Chronic Disease; Clonidine; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Pupil; Tonometry, Ocular	1972
[Effect of clonidine on intraocular pressure and pupil diameter]. Bucherei des Augenarztes, 1974, Volume: 63 Topics: Clonidine; Humans; Intraocular Pressure; Pilocarpine; Placebos; Pupil	1974
The effect of topical clonidine on intraocular pressure. Archives of ophthalmology (Chicago, Ill. : 1960), 1981, Volume: 99, Issue:7 Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine	1981
Influence of apraclonidine and pilocarpine alone and in combination on post laser trabeculoplasty pressure rise. The British journal of ophthalmology, 1994, Volume: 78, Issue:1 Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Blood Pressure; Clonidine; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Laser Therapy; Middle Aged; Pilocarpine; Prospective Studies; Trabeculectomy	1994
A comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%. Indian journal of ophthalmology, 1996, Volume: 44, Issue:2 Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Timolol	1996
Short-term effect of apraclonidine on intraocular pressure in glaucoma patients receiving timolol and pilocarpine. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1997, Volume: 211, Issue:6 Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Clonidine; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Prospective Studies; Timolol	1997
Efficacy of apraclonidine 1% versus pilocarpine 4% for prophylaxis of intraocular pressure spike after argon laser trabeculoplasty. Ophthalmology, 1999, Volume: 106, Issue:6 Topics: Aged; Clonidine; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Laser Therapy; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Trabeculectomy	1999
A prospective, long-term, randomized study of the efficacy and safety of the drug combination pilocarpine 1% with clonidine 0.06% or clonidine 0.125% versus timolol 0.25%. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:6 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Drug Administration Schedule; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Muscarinic Agonists; Pilocarpine; Safety; Timolol; Treatment Outcome	2002

Other Studies

33 other study(ies) available for pilocarpine and clonidine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Reversal of cycloheximide-induced amnesia by adrenergic receptor stimulation. Pharmacology, biochemistry, and behavior, 1977, Volume: 7, Issue:3 Topics: Amnesia; Animals; Brain Chemistry; Catecholamines; Clonidine; Cycloheximide; Drug Interactions; Humans; Isoproterenol; Male; Methyltyrosines; Mice; Mice, Inbred C57BL; Physostigmine; Pilocarpine; Piribedil; Receptors, Adrenergic; Receptors, Dopamine	1977
Antagonism of conditioned salivation in conscious dogs by antihypertensive drugs. Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:4 Topics: Animals; Antihypertensive Agents; Atropine; Carbidopa; Clonidine; Conditioning, Classical; Dogs; Drug Interactions; Female; Male; Methyldopa; Pilocarpine; Salivation	1977
Apraclonidine and argon laser trabeculoplasty. American journal of ophthalmology, 1992, Dec-15, Volume: 114, Issue:6 Topics: Adrenergic alpha-Agonists; Clonidine; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Pilocarpine; Postoperative Complications; Trabeculectomy	1992
Roles of gender and gonadectomy in pilocarpine and clonidine analgesia in rats. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1 Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Estrus; Female; Male; Orchiectomy; Ovariectomy; Pain Measurement; Pilocarpine; Rats; Rats, Inbred Strains; Regression Analysis; Sex Characteristics	1992
Determination of prostatic secretion in rats: effect of neurotransmitters and testosterone. The Prostate, 1991, Volume: 18, Issue:4 Topics: Acetylcholine; Acid Phosphatase; Animals; Carbachol; Castration; Clonidine; Denervation; Dose-Response Relationship, Drug; Isoproterenol; Male; Neurotransmitter Agents; Norepinephrine; Organ Size; Phenylephrine; Pilocarpine; Prostate; Rats; Rats, Inbred Strains; Testosterone	1991
Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus. Neuropharmacology, 1991, Volume: 30, Issue:1 Topics: Animals; Atropine; Clonidine; Electric Stimulation; Epilepsy; Hippocampus; Male; Parasympathomimetics; Pilocarpine; Propranolol; Pyramidal Tracts; Rats; Rats, Inbred Strains; Reserpine; Seizures; Sympathomimetics	1991
Effects of muscarinic receptor agonists and antagonists on alpha 2-adrenoceptors in rat brain. European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2 Topics: Animals; Atropine; Atropine Derivatives; Brain; Clonidine; Male; N-Methylscopolamine; Neurons; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Time Factors	1989
The role of apraclonidine hydrochloride in laser therapy for glaucoma. Transactions of the American Ophthalmological Society, 1989, Volume: 87 Topics: Acetazolamide; Adult; Aged; Animals; Clonidine; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Macaca fascicularis; Male; Middle Aged; Pilocarpine; Postoperative Complications; Timolol; Trabeculectomy	1989
Effects of biogenic amines and adrenergic drugs on oviposition in the cattle tick Boophilus: evidence for octopaminergic innervation of the oviduct. Experimental & applied acarology, 1989, Volume: 7, Issue:4 Topics: Adrenergic Agonists; Animals; Arecoline; Biogenic Amines; Cattle; Clonidine; Female; Naphazoline; Octopamine; Oviposition; Pilocarpine; Receptors, Adrenergic; Receptors, Biogenic Amine; Reserpine; Ticks; Tolazoline	1989
In vitro effects of a mixture of Escherichia coli heat-stable enterotoxins on chloride flux in everted jejunal sacs of male pigs. American journal of veterinary research, 1988, Volume: 49, Issue:10 Topics: Animals; Atropine; Bacterial Toxins; Chlorides; Clonidine; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Intestinal Absorption; Jejunum; Male; Morphine; Pilocarpine; Swine; Vasoactive Intestinal Peptide	1988
Role of medullary cholinoceptors in baroreflex bradycardia. Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:6 Topics: Animals; Blood Pressure; Carbachol; Cats; Clonidine; Female; Heart Rate; Male; Medulla Oblongata; Microinjections; Pilocarpine; Pressoreceptors; Receptors, Muscarinic; Tropanes	1986
[Experiences with clonidine with simultaneous psychopharmacologic medication]. Bucherei des Augenarztes, 1974, Volume: 63 Topics: Blood Pressure; Clonidine; Drug Interactions; Humans; Imipramine; Pilocarpine	1974
[Lowering of intraocular pressure with clonidin]. Klinische Monatsblatter fur Augenheilkunde, 1972, Volume: 160, Issue:2 Topics: Acetazolamide; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Combinations; Glaucoma; Humans; Imidazoles; Intraocular Pressure; Male; Miotics; Neostigmine; Ophthalmic Solutions; Pilocarpine	1972
[The effect of antiglaucoma drugs on the depth of the anterior chamber (I)]. Bollettino della Societa italiana di biologia sperimentale, 1982, Aug-15, Volume: 58, Issue:15 Topics: Adult; Anterior Chamber; Carbachol; Clonidine; Glaucoma; Humans; Middle Aged; Miotics; Moxisylyte; Pilocarpine; Propranolol; Quinuclidines; Timolol	1982
Influence of antiglaucoma drugs on axonal transport in the optic nerve. Ophthalmic research, 1983, Volume: 15, Issue:6 Topics: Adrenergic beta-Antagonists; Animals; Axonal Transport; Clonidine; Echothiophate Iodide; Epinephrine; Glaucoma; Intraocular Pressure; Neostigmine; Optic Nerve; Physostigmine; Pilocarpine; Rats	1983
Interaction of clonidine with chronotropic agents on isolated right atria. Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:1 Topics: Animals; Clonidine; Drug Interactions; Female; Glucagon; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Methylhistamines; Pilocarpine; Receptors, Adrenergic, beta; Stimulation, Chemical	1980
[Early effects of clonidine, epinephrine, and pilocarpine on the intraocular pressure and the episcleral venous pressure in normal volunteers (author's transl)]. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1980, Volume: 213, Issue:4 Topics: Adult; Clonidine; Epinephrine; Female; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Sclera; Venous Pressure	1980
Antidipsogenic effect of clonidine on angiotensin II-, hypertonic saline-, pilocarpine- and dehydration-induced water intakes. Brain research bulletin, 1981, Volume: 7, Issue:6 Topics: Angiotensin II; Animals; Clonidine; Dehydration; Drinking; Female; Pilocarpine; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic	1981
[Experience with timolol in consulting patients (author's transl)]. Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 176, Issue:5 Topics: Clonidine; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Timolol	1980
Acute and chronic effects of cholinesterase inhibitors and pilocarpine on the density and sensitivity of central and peripheral alpha 2-adrenoceptors. European journal of pharmacology, 1993, Jun-04, Volume: 236, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Brimonidine Tartrate; Cholinesterase Inhibitors; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Isoflurophate; Male; Neostigmine; Physostigmine; Pilocarpine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tyrosine 3-Monooxygenase; Vas Deferens	1993
Enhanced alpha2A-autoreceptor reserve for clonidine induced by reserpine and cholinomimetic agents in the rat vas deferens. British journal of pharmacology, 1997, Volume: 122, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Male; Muscle Contraction; Muscle, Smooth; Neostigmine; Parasympathomimetics; Pilocarpine; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reserpine; Vas Deferens	1997
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs. Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:12 Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular	1998
The rarity of clinically significant rise in intraocular pressure after laser peripheral iridotomy with apraclonidine. Ophthalmology, 1998, Volume: 105, Issue:12 Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Clonidine; Female; Glaucoma; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Retrospective Studies	1998
Ophthaproblem. Acute angle-closure glaucoma. Canadian family physician Medecin de famille canadien, 2000, Volume: 46 Topics: Acetazolamide; Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Clonidine; Diagnosis, Differential; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Timolol	2000
Immediate diode laser peripheral iridoplasty as treatment of acute attack of primary angle closure glaucoma: a preliminary study. Journal of glaucoma, 2001, Volume: 10, Issue:2 Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Clonidine; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Miotics; Pilocarpine; Timolol; Tonometry, Ocular; Treatment Outcome	2001
[General considerations related to ocular pharmacokinetic studies]. Archivos de la Sociedad Espanola de Oftalmologia, 2001, Volume: 76, Issue:11 Topics: Administration, Topical; Animals; Clonidine; Contrast Media; Eye; Fluorescein; Humans; Miotics; Pilocarpine	2001
[Usefulness of apraclonidine in the diagnosis of Horner syndrome]. Archivos de la Sociedad Espanola de Oftalmologia, 2009, Volume: 84, Issue:2 Topics: Adrenergic alpha-Agonists; Adult; Anisocoria; Birth Injuries; Brachial Plexus; Clonidine; Cocaine; Diagnosis, Differential; Female; Horner Syndrome; Humans; Infant; Male; Middle Aged; Neurilemmoma; Pilocarpine; Postoperative Complications; Thoracic Neoplasms; Tonic Pupil	2009
A pharmacologic pupillary test in the diagnosis of diabetic autonomic neuropathy. Korean journal of ophthalmology : KJO, 2009, Volume: 23, Issue:4 Topics: Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Diabetic Nephropathies; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Male; Middle Aged; Miosis; Miotics; Ophthalmic Solutions; Pilocarpine; Pupil; Reproducibility of Results	2009