pilocarpine has been researched along with bicuculline in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.38) | 18.7374 |
| 1990's | 7 (21.88) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 8 (25.00) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Alpern, HP; Greer, CA | 1 |
| Gale, K; Pazos, A; Peterson, CJ; Vinayak, S | 1 |
| Gale, K; Maggio, R; Sohn, E | 1 |
| Jope, RS; Ormandy, GC; Song, L | 1 |
| Bortolotto, ZA; Calderazzo-Filho, LS; Cavalheiro, EA; Diedrichs, S; Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Bortolotto, ZA; Cavalheiro, EA; Ikonomidou, C; Mello, LE; Turski, L; Turski, WA | 1 |
| Kuruvilla, A; Uretsky, NJ | 1 |
| Sowell, KL; Stringer, JL | 1 |
| Molnár, P; Nadler, JV; Okazaki, MM | 1 |
| Conlan, A; Gianutsos, G; Mayorga, AJ; Salamone, JD; Trevitt, JT | 1 |
| Hardison, JL; Nadler, JV; Okazaki, MM | 1 |
| Bortolotto, ZA; Cavalheiro, EA; Hamani, C; Mello, LE; Sakabe, S | 1 |
| Goodhead, LH; Mitchell, SN; Moss, S; Sharott, A | 1 |
| Hagemann, G; Koch, UR; Köhling, R; Redecker, C; Speckmann, EJ; Straub, H | 1 |
| Arizzi, MN; Correa, M; Ishiwari, K; Salamone, JD; Wisniecki, A | 1 |
| Crowley, JC; Katz, LC; Mizrahi, A; Shtoyerman, E | 1 |
| Behr, J; Heinemann, U; Kivi, A; Knopp, A; Wozny, C | 1 |
| Jiao, Y; Nadler, JV; Timofeeva, O; Tu, B | 1 |
| Arisi, GM; Bertti, P; Dal-Cól, ML; Del Vecchio, F; Fernandes, A; Foresti, ML; Furtado, MA; Garcia-Cairasco, N; Rodrigues, MC; Rossetti, F; Santos, FL | 1 |
| Gal, A; Hentschke, M; Hentschke, S; Hermans-Borgmeyer, I; Hübner, CA; Jentsch, TJ; Kurth, I; Seidenbecher, T; Wiemann, M | 1 |
| Nadler, JV; Timofeeva, O | 1 |
| Chapman, CA; Hamam, BN; Poirier, G; Sinai, M | 1 |
| Gabriel, S; Heinemann, U; Lehmann, TN; Sandow, N; Zahn, RK | 1 |
| Khan, RS; Mathew, J; Paulose, CS; Peeyush Kumar, T | 1 |
| Andrade, D; Bittencourt, S; Covolan, L; Dubiela, FP; Hamani, C; Lozano, A; Mello, LE; Queiroz, C | 1 |
| Mathew, J; Paulose, CS; Sadanandan, J; Soman, S | 1 |
| Paz, C; Retana-Márquez, S; Rubio, C; Rubio-Osornio, M; Verónica Custodio, ML | 1 |
| Cyr, M; Dontigny, E; Massicotte, G; Patenaude, C | 1 |
| Cha, YM; Chen, LF; Frank, CL; West, AE; Wijayatunge, R; Zannas, AS | 1 |
| Magagna-Poveda, A; Moretto, JN; Scharfman, HE | 1 |
| Josiane Ojong, L; Jules Fifen, J; Kameni Njapdounke, JS; Kavaye Kandeda, A; Ngo Bum, E; Nkamguie Nkantchoua, GC; Sotoing Taiwe, G | 1 |
| An, L; Chen, T; Guo, S; Huang, X; Liu, L; Mei, Q; Sun, X; Tian, H; Wang, R; Zhao, Y | 1 |
1 review(s) available for pilocarpine and bicuculline
| Article | Year |
|---|---|
In vivo experimental models of epilepsy.
Topics: Aluminum Hydroxide; Animals; Bicuculline; Cobalt; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; Epilepsy, Reflex; Flurothyl; gamma-Aminobutyric Acid; Humans; Kainic Acid; Kindling, Neurologic; Muscarinic Agonists; Papio; Penicillins; Pentylenetetrazole; Pilocarpine; Tetanus Toxin; Zinc Compounds | 2010 |
31 other study(ies) available for pilocarpine and bicuculline
| Article | Year |
|---|---|
Mediation of myoclonic seizures by dopamine and clonic seizures by acetylcholine and GABA.
Topics: Animals; Apomorphine; Bicuculline; Dose-Response Relationship, Drug; Flurothyl; Haloperidol; Isoquinolines; Mice; Myoclonus; Pilocarpine; Scopolamine; Seizures | 1977 |
A rodent model of focally evoked self-sustaining status epilepticus.
Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1992 |
Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models.
Topics: Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Isoniazid; Kainic Acid; Male; Microinjections; Muscimol; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Synaptic Transmission | 1991 |
Analysis of the convulsant-potentiating effects of lithium in rats.
Topics: Animals; Bicuculline; Chlorides; Convulsants; Drug Synergism; Hippocampus; Kainic Acid; Lithium; Lithium Chloride; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1991 |
Paradoxical anticonvulsant activity of the gamma-aminobutyrate antagonist bicuculline methiodide in the rat striatum.
Topics: Animals; Anticonvulsants; Bicuculline; Corpus Striatum; Electroencephalography; GABA Antagonists; Male; Microinjections; Models, Neurological; Neurons; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Synapses | 1991 |
Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Animals; Benzodiazepinones; Bicuculline; Brain; Carbolines; Convulsants; Electroencephalography; Flumazenil; Male; Motor Activity; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1985 |
Effect of intrastriatal administration of cholinergic and GABAergic agonists on apomorphine-induced circling.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Drug Interactions; gamma-Aminobutyric Acid; Humans; Injections; Male; Muscimol; Parasympathomimetics; Picrotoxin; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Scopolamine; Stereotyped Behavior | 1984 |
Kainic acid, bicuculline, pentylenetetrazol and pilocarpine elicit maximal dentate activation in the anesthetized rat.
Topics: Anesthesia; Animals; Bicuculline; Convulsants; Electric Stimulation; Epilepsy; Evoked Potentials; Hippocampus; Kainic Acid; Male; Pentylenetetrazole; Pilocarpine; Rats; Rats, Sprague-Dawley | 1994 |
Recurrent mossy fiber pathway in rat dentate gyrus: synaptic currents evoked in presence and absence of seizure-induced growth.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Dentate Gyrus; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Feedback; GABA Antagonists; Kainic Acid; Male; Mossy Fibers, Hippocampal; N-Methylaspartate; Organ Culture Techniques; Parasympathomimetics; Patch-Clamp Techniques; Perforant Pathway; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Status Epilepticus; Synapses | 1999 |
Striatal and nigral D1 mechanisms involved in the antiparkinsonian effects of SKF 82958 (APB): studies of tremulous jaw movements in rats.
Topics: Animals; Antiparkinson Agents; Benzazepines; Bicuculline; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; GABA Antagonists; Jaw; Male; Movement; Muscarinic Agonists; Neostriatum; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Substantia Nigra | 1999 |
Modest increase in extracellular potassium unmasks effect of recurrent mossy fiber growth.
Topics: Action Potentials; Animals; Anticonvulsants; Bicuculline; Cyclopropanes; Extracellular Space; GABA Antagonists; Glycine; Male; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neuronal Plasticity; Pilocarpine; Potassium; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2000 |
Inhibitory role of the zona incerta in the pilocarpine model of epilepsy.
Topics: Animals; Bicuculline; Brain Mapping; Disease Models, Animal; Electroencephalography; Epilepsy; GABA Agonists; GABA Antagonists; Injections, Intraventricular; Male; Muscimol; Pilocarpine; Rats; Rats, Wistar; Subthalamus | 2002 |
Role of muscarinic receptors in the activation of the ventral subiculum and the consequences for dopamine release in the nucleus accumbens.
Topics: Animals; Atropine; Bicuculline; Bridged-Ring Compounds; Carbachol; Cholinergic Agonists; Diamines; Dopamine; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nucleus Accumbens; Oxotremorine; Pilocarpine; Pyridines; Rats; Receptors, Muscarinic; Spiro Compounds; Thiadiazoles; Tropanes | 2003 |
Differential sensitivity to induction of spreading depression by partial disinhibition in chronically epileptic human and rat as compared to native rat neocortical tissue.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Chronic Disease; Cortical Spreading Depression; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; GABA Antagonists; Humans; In Vitro Techniques; Membrane Potentials; Microelectrodes; Neocortex; Neuroglia; Neurons; Parasympathomimetics; Pilocarpine; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2003 |
Motor effects of GABA(A) antagonism in globus pallidus: studies of locomotion and tremulous jaw movements in rats.
Topics: Animals; Behavior, Animal; Bicuculline; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Globus Pallidus; Haloperidol; Jaw; Locomotion; Male; Movement; Pilocarpine; Rats; Rats, Sprague-Dawley; Tremor | 2003 |
High-resolution in vivo imaging of hippocampal dendrites and spines.
Topics: Animals; Bicuculline; Dendrites; Electroencephalography; Epilepsy; GABA Antagonists; Green Fluorescent Proteins; Hippocampus; Luminescent Proteins; Mice; Mice, Transgenic; Microscopy, Confocal; Pilocarpine; Pyramidal Cells; Reproducibility of Results; Sensitivity and Specificity; Time Factors | 2004 |
Cellular and network properties of the subiculum in the pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Bicuculline; Cell Count; Dendrites; Dendritic Spines; Disease Models, Animal; Epilepsy, Temporal Lobe; Fluoresceins; GABA Antagonists; Hippocampus; In Vitro Techniques; Lysine; Membrane Potentials; Muscarinic Agonists; Nerve Net; Patch-Clamp Techniques; Pilocarpine; Pyramidal Cells; Rats; Rats, Wistar; Staining and Labeling | 2005 |
Spontaneous release of neuropeptide Y tonically inhibits recurrent mossy fiber synaptic transmission in epileptic brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Benzazepines; Bicuculline; Convulsants; Dentate Gyrus; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mossy Fibers, Hippocampal; Neuropeptide Y; Patch-Clamp Techniques; Perforant Pathway; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide Y; Status Epilepticus; Synaptic Transmission; Tetrodotoxin | 2005 |
Correlation between shaking behaviors and seizure severity in five animal models of convulsive seizures.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Disease Models, Animal; Electric Stimulation; Electroencephalography; Functional Laterality; GABA Antagonists; Hippocampus; Kindling, Neurologic; Male; Microscopy, Interference; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Rats; Rats, Wistar; Scopolamine; Seizures; Stereotaxic Techniques; Time Factors | 2005 |
Mice with a targeted disruption of the Cl-/HCO3- exchanger AE3 display a reduced seizure threshold.
Topics: Animals; Antiporters; Bicuculline; Brain; Chloride-Bicarbonate Antiporters; Convulsants; Dentate Gyrus; Gene Targeting; Hydrogen-Ion Concentration; Mice; Mice, Knockout; Pentylenetetrazole; Pilocarpine; Seizures; Sensory Thresholds | 2006 |
Facilitation of granule cell epileptiform activity by mossy fiber-released zinc in the pilocarpine model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Bicuculline; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Mossy Fibers, Hippocampal; Neurons; Perforant Pathway; Pilocarpine; Potassium; Rats; Rats, Sprague-Dawley; Zinc | 2006 |
Cholinergic suppression of excitatory synaptic responses in layer II of the medial entorhinal cortex.
Topics: Animals; Behavior, Animal; Bicuculline; Carbachol; Cholinesterase Inhibitors; Electric Stimulation; Electrophysiology; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Extracellular Space; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Membrane Potentials; Muscarinic Agonists; Neurons; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Rats, Long-Evans; Theta Rhythm | 2007 |
Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoisobutyric Acids; Animals; Bicuculline; Disease Models, Animal; Entorhinal Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamine; In Vitro Techniques; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2009 |
Behavioral deficit and decreased GABA receptor functional regulation in the cerebellum of epileptic rats: effect of Bacopa monnieri and bacoside A.
Topics: Animals; Anticonvulsants; Behavioral Symptoms; Bicuculline; Carbamazepine; Cerebellum; Disease Models, Animal; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Phytotherapy; Pilocarpine; Plant Preparations; Protein Binding; Rats; Rats, Wistar; Receptors, GABA; Saponins; Triterpenes; Tritium | 2010 |
Microinjection of GABAergic agents into the anterior nucleus of the thalamus modulates pilocarpine-induced seizures and status epilepticus.
Topics: Animals; Anterior Thalamic Nuclei; Bicuculline; Convulsants; Electroencephalography; GABA Agents; Humans; Male; Microinjections; Muscimol; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2010 |
Decreased GABA receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of Bacopa monnieri and bacoside-A.
Topics: Animals; Anticonvulsants; Bacopa; Basal Ganglia; Behavior, Animal; Bicuculline; Binding, Competitive; Carbamazepine; Disease Models, Animal; Down-Regulation; GABA Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A; Recognition, Psychology; RNA, Messenger; Saponins; Status Epilepticus; Triterpenes | 2010 |
Sphingomyelinase selectively reduces M1 muscarinic receptors in rat hippocampal membranes.
Topics: Animals; Arrestins; beta-Arrestins; Bicuculline; Biotinylation; Cell Membrane; Drug Interactions; Excitatory Amino Acid Antagonists; G-Protein-Coupled Receptor Kinase 2; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; Immunoprecipitation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Muscarinic Agonists; Patch-Clamp Techniques; Pilocarpine; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sphingomyelin Phosphodiesterase; Time Factors; Valine | 2012 |
The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival.
Topics: 4-Aminopyridine; Animals; Astrocytes; Bicuculline; Cell Survival; Cells, Cultured; Disease Models, Animal; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; Jumonji Domain-Containing Histone Demethylases; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Neurons; Pilocarpine; Potassium Channel Blockers; RNA Interference; Seizures | 2014 |
Increased gyrification and aberrant adult neurogenesis of the dentate gyrus in adult rats.
Topics: Analysis of Variance; Animals; Atropine Derivatives; Bicuculline; Bromodeoxyuridine; Dentate Gyrus; Excitatory Amino Acid Agonists; Female; GABA-A Receptor Antagonists; In Vitro Techniques; Kainic Acid; Male; Muscarinic Agonists; Neurogenesis; Neuronal Plasticity; Neurons; Parasympatholytics; Phosphopyruvate Hydratase; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors | 2017 |
Anticonvulsant effects of Senna spectabilis on seizures induced by chemicals and maximal electroshock.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Electric Stimulation; Flumazenil; Male; Mice; Pentylenetetrazole; Pilocarpine; Plant Extracts; Plant Leaves; Plants, Medicinal; Random Allocation; Seizures; Senna Plant | 2018 |
LMR-101, a novel derivative of propofol, exhibits potent anticonvulsant effects and possibly interacts with a novel target on γ-aminobutyric acid type A receptors.
Topics: Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Electroencephalography; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Mice; Muscarinic Agonists; Pentylenetetrazole; Phenols; Pilocarpine; Propofol; Rats; Receptors, GABA-A; Seizures; Status Epilepticus | 2021 |