Compounds > pifithrin
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pifithrin and temozolomide

pifithrin has been researched along with temozolomide in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cairncross, JG; Mymryk, JS; Xu, GW1
Allen, J; Avery-Kiejda, KA; Hersey, P; Mhaidat, NM; Scott, RJ; Zhang, XD1
Berger, MS; Dinca, EB; Haas-Kogan, DA; James, CD; Lu, KV; Pieper, RO; Prados, MD; Sarkaria, JN; Vandenberg, SR1
Hromas, R; Jaiswal, AS; Jani, J; Law, BK; Narayan, S; Panda, H; Sharma, J1

Other Studies

4 other study(ies) available for pifithrin and temozolomide

ArticleYear
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Damage; Drug Interactions; Glioma; Humans; Temozolomide; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2005
Temozolomide induces senescence but not apoptosis in human melanoma cells.
    British journal of cancer, 2007, Nov-05, Volume: 97, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Benzothiazoles; Cell Division; Cellular Senescence; Dacarbazine; G2 Phase; Humans; Lymphoma; Melanoma; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2007
p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts.
    Cancer research, 2008, Dec-15, Volume: 68, Issue:24

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzothiazoles; Brain Neoplasms; Dacarbazine; Drug Synergism; Glioblastoma; Humans; Mice; Poly(ADP-ribose) Polymerases; Temozolomide; Toluene; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2008
NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Apoptosis; Benzothiazoles; Cell Cycle; Cell Cycle Checkpoints; Cellular Senescence; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Dacarbazine; DNA Damage; DNA Polymerase beta; DNA Repair; Enzyme Inhibitors; HCT116 Cells; Humans; Small Molecule Libraries; Sulfhydryl Compounds; Sulfonamides; Temozolomide; Toluene; Triazoles; Tumor Suppressor Protein p53

2015