Compounds > pifithrin
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pifithrin and staurosporine

pifithrin has been researched along with staurosporine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bosykh, DA; Burdelya, LG; Chernova, OB; Gudkov, AV; Komarov, PG; Komarova, EA; Macklis, RM; Pavlovska, I; Sathe, S; Shyshynova, I; Skaliter, R; Strom, E1
Alves da Costa, C; Ancolio, K; Checler, F; Mattson, MP1
Charlot, JF; Mougin, C; Nicolier, M; Prétet, JL1
Chen, B; Longtine, MS; Nelson, DM; Sadovsky, Y1

Other Studies

4 other study(ies) available for pifithrin and staurosporine

ArticleYear
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation.
    Nature chemical biology, 2006, Volume: 2, Issue:9

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Benzothiazoles; Cell Line; Dexamethasone; Gamma Rays; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria; Protein Binding; Protein Transport; Radiation Injuries, Experimental; Radiation-Protective Agents; Thiazoles; Thymus Gland; Toluene; Transcriptional Activation; Tumor Suppressor Protein p53; Ultraviolet Rays

2006
The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.
    The Journal of biological chemistry, 2003, Apr-04, Volume: 278, Issue:14

    Topics: Animals; Apoptosis; Benzothiazoles; Caspase 3; Caspases; Cells, Cultured; Dimerization; Enzyme Inhibitors; Fibroblasts; Gene Expression; Humans; Kidney; Membrane Proteins; Mice; Peptide Fragments; Phenotype; Presenilin-2; Protein Structure, Tertiary; Staurosporine; Thiazoles; Toluene; Tumor Suppressor Protein p53

2003
Modulation of p53 transcriptional activity by PRIMA-1 and Pifithrin-alpha on staurosporine-induced apoptosis of wild-type and mutated p53 epithelial cells.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:5

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Cell Culture Techniques; Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Viral; DNA, Neoplasm; Drug Combinations; Enzyme Inhibitors; Epithelial Cells; Female; HeLa Cells; Humans; Membrane Potentials; Membrane Proteins; Mitochondria; Mutation; Nerve Tissue Proteins; Papillomaviridae; Staurosporine; Thiazoles; Toluene; Transcription, Genetic; Tumor Suppressor Protein p53

2006
Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts.
    American journal of physiology. Cell physiology, 2010, Volume: 299, Issue:5

    Topics: Animals; Apoptosis; bcl-Associated Death Protein; Benzothiazoles; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Hypoxia; Imidazoles; Oxygen; Piperazines; Pregnancy; Staurosporine; Toluene; Trophoblasts; Tumor Suppressor Protein p53

2010