pifithrin has been researched along with pyrazolanthrone in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ng, LT; Wu, SJ | 1 |
| Clair, DK; García-Cazarín, ML; Piascik, MT; Smith, JL | 1 |
| Aloi, C; Altieri, P; Barisione, C; Barsotti, A; Brunelli, C; Fugazza, G; Garibaldi, S; Ghigliotti, G; Spallarossa, P | 1 |
| Das, HK; Lee, S | 1 |
| Fan, S; Ikejima, T; Li, L; Onodera, S; Qi, M; Tashiro, S; Yao, G; Yu, Y | 1 |
| Bu, HQ; Chen, L; Cui, JH; Huang, H; Li, Y; Liu, DL; Wei, WT | 1 |
| Giri, RK; Sidhar, H | 1 |
| Cai, X; Zhu, S | 1 |
8 other study(ies) available for pifithrin and pyrazolanthrone
| Article | Year |
|---|---|
MAPK inhibitors and pifithrin-alpha block cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells.
Topics: Anthracenes; Antineoplastic Agents, Phytogenic; Apoptosis; Benzothiazoles; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cinnamomum aromaticum; Enzyme Inhibitors; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Phytotherapy; Plant Extracts; Toluene | 2007 |
The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism.
Topics: Acetophenones; Adrenergic alpha-1 Receptor Antagonists; Anthracenes; Aorta; Apoptosis; Benzothiazoles; Cells, Cultured; Culture Media, Serum-Free; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitochondria; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Pyridines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Time Factors; Toluene; Tumor Suppressor Protein p53 | 2008 |
Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.
Topics: Animals; Animals, Newborn; Anthracenes; Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Cells, Cultured; Cellular Senescence; Checkpoint Kinase 2; Cytoskeleton; Dose-Response Relationship, Drug; Doxorubicin; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitosis; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phenotype; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Rats, Sprague-Dawley; RNA Interference; Telomeric Repeat Binding Protein 1; Telomeric Repeat Binding Protein 2; Time Factors; Toluene; Tumor Suppressor Protein p53 | 2009 |
Transcriptional regulation of the presenilin-1 gene controls gamma-secretase activity.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Anthracenes; Benzothiazoles; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA Primers; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genetic Vectors; Humans; JNK Mitogen-Activated Protein Kinases; Peptide Fragments; Presenilin-1; Reverse Transcriptase Polymerase Chain Reaction; Toluene | 2010 |
P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Benzothiazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Genes, p53; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Reactive Oxygen Species; Silybin; Silymarin; Toluene; Tumor Suppressor Protein p53; Vulvar Neoplasms | 2012 |
Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53- and caspase-dependent induction of p38 MAPK.
Topics: Anthracenes; Apoptosis; Benzothiazoles; Caspase 3; Caspase 9; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diterpenes, Kaurane; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; G1 Phase Cell Cycle Checkpoints; Humans; Imidazoles; Isodon; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Plant Preparations; Pyridines; RNA, Messenger; Toluene; Tumor Suppressor Protein p53 | 2014 |
Induction of Bex genes by curcumin is associated with apoptosis and activation of p53 in N2a neuroblastoma cells.
Topics: Androstadienes; Animals; Anthracenes; Apoptosis; Benzothiazoles; Cell Line, Tumor; Curcumin; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; JNK Mitogen-Activated Protein Kinases; Mice; Models, Biological; Nerve Tissue Proteins; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Signal Transduction; Time Factors; Toluene; Tumor Suppressor Protein p53; Wortmannin | 2017 |
Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.
Topics: Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; Osteosarcoma; Prognosis; Signal Transduction; Voltage-Dependent Anion Channel 1 | 2023 |