Compounds > pifithrin
Page last updated: 2024-08-16

pifithrin and glutamic acid

pifithrin has been researched along with glutamic acid in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Camandola, S; Chan, SL; Culmsee, C; Greig, NH; Guo, Z; Mattson, MP; Yu, QS; Zhu, X1
Dubinsky, JM; Lakkaraju, A; Low, WC; Rahman, YE1
Fujiwara, T; Morimoto, K1
Greig, NH; Li, Y; Pick, CG; Rachmany, L; Rubovitch, V; Tweedie, D; Wang, JY; Yu, QS1
Culmsee, C; Diemert, S; Ganjam, GK; Neitemeier, S1
Ahn, KC; Dunbar, GL; Hall, TC; Learman, CR; MacKenzie, EM; Song, MS; Weaver, CL1

Other Studies

6 other study(ies) available for pifithrin and glutamic acid

ArticleYear
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.
    Journal of neurochemistry, 2001, Volume: 77, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Antineoplastic Agents; Benzothiazoles; Brain Ischemia; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; Prodrugs; Rats; Rats, Sprague-Dawley; Seizures; Thiazoles; Toluene; Tumor Suppressor Protein p53

2001
Neurons are protected from excitotoxic death by p53 antisense oligonucleotides delivered in anionic liposomes.
    The Journal of biological chemistry, 2001, Aug-24, Volume: 276, Issue:34

    Topics: Animals; Anions; Base Sequence; Benzothiazoles; Cell Death; Cell Line; Cricetinae; DNA Primers; Drug Carriers; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Liposomes; Neurons; Neuroprotective Agents; Oligonucleotides, Antisense; Osmolar Concentration; Rats; Thiazoles; Toluene; Tumor Suppressor Protein p53

2001
Inhibition of p53 transactivation functionally interacts with microtubule stabilization to suppress excitotoxicity-induced axon degeneration.
    Biochemical and biophysical research communications, 2012, Oct-12, Volume: 427, Issue:1

    Topics: Animals; Axons; Benzothiazoles; Cells, Cultured; Dynactin Complex; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Microtubules; Mitochondria; Mitochondrial Diseases; Nerve Degeneration; Neurotoxins; Paclitaxel; Rats; Rats, Wistar; Toluene; Transcriptional Activation; Tumor Suppressor Protein p53

2012
Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Benzothiazoles; Brain Injuries; Cell Death; Cell Line; Cell Survival; Cognitive Dysfunction; Dentate Gyrus; Glutamic Acid; Humans; Male; Maze Learning; Mice; Neurons; Oxidative Stress; Primary Cell Culture; Rats; Toluene; Tumor Suppressor Protein p53

2013
Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition.
    Apoptosis : an international journal on programmed cell death, 2014, Volume: 19, Issue:12

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Benzothiazoles; Cell Line, Tumor; Cell Membrane; Gene Knockout Techniques; Glutamic Acid; Hippocampus; Humans; Lipid Peroxidation; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; RNA, Small Interfering; Toluene; Tumor Suppressor Protein p53

2014
Inhibition of p53 attenuates ischemic stress-induced activation of astrocytes.
    Neuroreport, 2015, Sep-30, Volume: 26, Issue:14

    Topics: Animals; Astrocytes; Benzothiazoles; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Central Nervous System Agents; Glucose; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Neurons; Rats, Sprague-Dawley; RNA Interference; Stress, Physiological; Toluene; Tumor Suppressor Protein p53

2015