pifithrin has been researched along with fluorouracil in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bosykh, DA; Burdelya, LG; Chernova, OB; Gudkov, AV; Komarov, PG; Komarova, EA; Macklis, RM; Pavlovska, I; Sathe, S; Shyshynova, I; Skaliter, R; Strom, E | 1 |
| Mahyar-Roemer, M; Roemer, K | 1 |
| Guo, SW; Guo, XL; Hu, F; Li, R; Wei, LX; Wu, MC; Ye, F; Zhang, JW; Zhang, SS; Zhao, QD; Zong, C | 1 |
| Ki, SH; Park, EY; Seo, K; Shin, SM | 1 |
| Li, Y; Wang, Y; Yang, L; Yin, D | 1 |
5 other study(ies) available for pifithrin and fluorouracil
| Article | Year |
|---|---|
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Benzothiazoles; Cell Line; Dexamethasone; Gamma Rays; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria; Protein Binding; Protein Transport; Radiation Injuries, Experimental; Radiation-Protective Agents; Thiazoles; Thymus Gland; Toluene; Transcriptional Activation; Tumor Suppressor Protein p53; Ultraviolet Rays | 2006 |
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.
Topics: Adenocarcinoma; Alleles; Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzothiazoles; Butyrates; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Demecolcine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Recombination, Genetic; Resveratrol; Stilbenes; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Benzothiazoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Fluorouracil; Hep G2 Cells; Humans; Liver Neoplasms; Mitochondria, Liver; Reactive Oxygen Species; Toluene; Tumor Suppressor Protein p53 | 2014 |
5-Fluorouracil inhibits cell migration by induction of Sestrin2 in colon cancer cells.
Topics: Antimetabolites, Antineoplastic; Antioxidants; Benzothiazoles; Cell Movement; Colorectal Neoplasms; Fluorouracil; Gene Knockdown Techniques; HCT116 Cells; Heat-Shock Proteins; HT29 Cells; Humans; NF-E2-Related Factor 2; Nuclear Proteins; Phosphorylation; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction; Toluene; Transcriptional Activation; Tumor Suppressor Protein p53; Up-Regulation | 2017 |
Intermittent low dose irradiation enhances the effectiveness of radio- and chemo-therapy for human colorectal adenocarcinoma cell line HT-29.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Benzothiazoles; Cell Proliferation; Chemoradiotherapy; Colorectal Neoplasms; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluorouracil; HT29 Cells; Humans; Imidazoles; MAP Kinase Signaling System; Morpholines; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrones; Radiation Dosage; Toluene; Tumor Suppressor Protein p53 | 2017 |