Page last updated: 2024-08-23

picrotoxin and phenytoin

picrotoxin has been researched along with phenytoin in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	34 (75.56)	18.7374
1990's	4 (8.89)	18.2507
2000's	3 (6.67)	29.6817
2010's	4 (8.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bissada, NK; Finkbeiner, AE; Welch, LT	1
Costa, E; Guidotti, A; Mao, CC; Suria, A	1
Costa, E; Guidotti, A; Mao, CC	1
Fukumori, R; Kitagawa, H; Minegishi, A; Nakagawa, I; Satoh, T; Yanaura, S	1
Dóda, M; György, L; Koltai, MZ	1
Aickin, CC; Deisz, RA; Lux, HD	3
Carrer, H; Meyerson, BJ	1
Cole, FR; Nelson, RB	1
Mothon, S; Reichlin, S	1
Kulkarni, SK; Ticku, MK	1
Griffith, WH; Taylor, L	1
Spero, L	1
Kantarev, N; Parisheva, Z; Toreva, D	1
Piredda, SG; Swinyard, EA; Woodhead, JH	1
Vernadakis, A; Woodbury, DM	1
Baxter, BL	1
Buchanan, AS; Laycock, GM; Shulman, A	1
Izquierdo, I	1
Chai, CY; Lee, TM; Li, RC	1
Kazama, K	1
Baxter, MG; Miller, AA; Webster, RA	1
Swinyard, EA	1
Bartels, E; Rosenberg, P	1
File, SE; Pellow, S	2
Calder, LD; Karler, R; Turkanis, SA	1
Nicoll, RA; Wojtowicz, JM	1
Simmonds, MA	1
Adams, PR; Banks, FW; Constanti, A	2
Schwarz, M; Sontag, KH; Turski, L	1
Gallager, DW; Mallorga, P; Tallman, JF	1
Amabeoku, GJ; Chikuni, O	1
Godlevsky, LS; Mazarati, AM; Shandra, AA; Vastyanov, RS	1
Chang, CC; Chiou, LC; Ling, JY	1
SIGG, EB; WARNER, CL; YEN, HC	1
Chouinard, SW; Littleton, JT; Saraswati, S; Stilwell, GE	1
Alves, PB; Antoniolli, AR; Blank, AF; Bonjardim, LR; Leite, BS; Lessa, NM; Quintans-Júnior, LJ; Santos, MR; Souza, TT	1
Nwafor, PA; Okokon, JE	1
Ahmad, M; Raza, ML; Shaheen, F; Simjee, SU; Zeeshan, M	1
Baines, RA; Günay, C; Lin, WH; Marley, R; Prinz, AA	1
Ananthalakshmi, KV; Edafiogho, IO; Kombian, SB; Phillips, OA; Qaddoumi, MG	1
Baines, RA; Fan, YN; Masullo, L; Streit, AK	1

Reviews

5 review(s) available for picrotoxin and phenytoin

Article	Year
Uropharmacology: X. Central nervous system stimulants and depressants. Urology, 1979, Volume: 13, Issue:4 Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract	1979
New concepts on the mechanism of action of benzodiazepines. Life sciences, 1975, Jul-15, Volume: 17, Issue:2 Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra	1975
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods. Epilepsia, 1969, Volume: 10, Issue:2 Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; Electroshock; Humans; Methionine Sulfoximine; Methods; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine; Thiosemicarbazones; Trimethadione; Urea	1969
Behavioural actions of Ro 5-4864: a peripheral-type benzodiazepine? Life sciences, 1984, Jul-16, Volume: 35, Issue:3 Topics: Animals; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain; Convulsants; Drug Interactions; Flumazenil; Humans; Isoquinolines; Kidney; Phenytoin; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A	1984
Changes in CNS sensitivity to cannabinoids with repeated treatment: tolerance and auxoesthesia. NIDA research monograph, 1984, Volume: 54 Topics: Animals; Brain; Cannabidiol; Cannabinoids; Dronabinol; Drug Tolerance; Electroshock; Kindling, Neurologic; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures	1984

Other Studies

40 other study(ies) available for picrotoxin and phenytoin

Article	Year
Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam. Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 289, Issue:4 Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Cerebellum; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoniazid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Strychnine	1975
Effect of tryptophol on pentylenetetrazol and picrotoxin induced convulsion in mice. Life sciences, 1979, May-28, Volume: 24, Issue:22 Topics: Animals; Anticonvulsants; Brain; Indoles; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures	1979
Effects of phenytoin on sympathetic reflex responses in the cat. European journal of pharmacology, 1978, Jun-15, Volume: 49, Issue:4 Topics: Animals; Blood Pressure; Cats; Dimethylphenylpiperazinium Iodide; Evoked Potentials; Female; In Vitro Techniques; Male; Nictitating Membrane; Ouabain; Pentylenetetrazole; Phenytoin; Picrotoxin; Reflex; Scopolamine; Sympathetic Nervous System	1978
The effect of diphenylhydantoin and picrotoxin on post-synaptic inhibition [proceedings]. The Journal of physiology, 1978, Volume: 284 Topics: Animals; Astacoidea; Dose-Response Relationship, Drug; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Phenytoin; Picrotoxin; Synapses	1978
Effect of CNS depressants and stimulants on latency for the appearance of copulatory response in the female rat. Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:5 Topics: 20-alpha-Dihydroprogesterone; Adrenal Glands; Animals; Copulation; Estradiol; Ether; Female; Hexobarbital; Ovary; Phenytoin; Picrotoxin; Rats; Strychnine; Time Factors	1976
The convulsive profile of Cicuta douglasii (water hemlock). Proceedings of the Western Pharmacology Society, 1976, Volume: 19 Topics: Animals; Anticonvulsants; Convulsants; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Plant Extracts	1976
Carbamazepine and phenytoin inhibit somatostatin release from dispersed cerebral cells in culture. Annals of neurology, 1991, Volume: 29, Issue:4 Topics: Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Colforsin; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Channels; Somatostatin	1991
Interaction between GABAergic anticonvulsants and the NMDA receptor antagonist MK 801 against MES- and picrotoxin-induced convulsions in rats. Life sciences, 1989, Volume: 44, Issue:18 Topics: Animals; Anticonvulsants; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Electroshock; Ethanol; Male; Motor Activity; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Stereotyped Behavior	1989
Phenytoin reduces excitatory synaptic transmission and post-tetanic potentiation in the in vitro hippocampus. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: Animals; Dendrites; Electrophysiology; Evoked Potentials; Hippocampus; Phenytoin; Picrotoxin; Pyramidal Tracts; Rats; Synaptic Transmission	1988
Modulation of specific [3H]phenytoin binding by benzodiazepines. Neurochemical research, 1985, Volume: 10, Issue:6 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flumazenil; In Vitro Techniques; Male; Phenytoin; Picrotoxin; Potassium Chloride; Rats; Receptors, GABA-A; Sodium Chloride; Stimulation, Chemical; Time Factors	1985
Changes in GABA content of the brain and sensitivity to GABA-antagonists during and after repetitive treatment of rats with diphenilhydantoin. Folia medica, 1988, Volume: 30, Issue:3 Topics: Animals; Brain; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Seizures	1988
Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3 Topics: Animals; Anticonvulsants; Bicuculline; Electroshock; Ethosuximide; Male; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures; Valproic Acid	1985
The developing animal as a model. Epilepsia, 1969, Volume: 10, Issue:2 Topics: Age Factors; Animals; Barbiturates; Brain; Central Nervous System; Electric Stimulation; Electroshock; Fetus; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Reflex; Seizures; Spinal Cord; Strychnine; Synaptic Transmission; Time Factors	1969
The effect of selected drugs on the "emotional" behavior elicited via hypothalamic stimulation. International journal of neuropharmacology, 1968, Volume: 7, Issue:1 Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpromazine; Depression, Chemical; Electric Stimulation; Emotions; Hypothalamus; Imipramine; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Pregnanediones; Reserpine; Scopolamine; Stimulation, Chemical; Strychnine; Tremorine	1968
Action of central nervous system stimulant and depressant drugs in the intact animal. 4. Surface activity of drugs with central stimulant depressant, or dual stimulant-depressant action. European journal of pharmacology, 1969, Volume: 7, Issue:1 Topics: Air; Amobarbital; Barbiturates; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Depression, Chemical; Glutarates; Hypnotics and Sedatives; Oxazines; Pentobarbital; Pentylenetetrazole; Phenytoin; Picrotoxin; Pregnanediones; Solutions; Stimulation, Chemical; Surface Properties; Surface Tension; Trimethadione	1969
Effect on pseudoconditioning of drugs with known central nervous activity. Psychopharmacologia, 1974, Volume: 38, Issue:3 Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione	1974
Effects of diphenylhydantoin on cardiac arrhythmias induced by picrotoxin. The Chinese journal of physiology, 1974, Dec-31, Volume: 21, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Heart; Heart Rate; Heart Ventricles; Male; Myocardial Contraction; Phenytoin; Picrotoxin; Vagotomy	1974
[Effects of various pharmacological agents on neocortical seizure activities in the rabbit]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1972, Volume: 74, Issue:7 Topics: Aminobutyrates; Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Electroencephalography; Evoked Potentials; Lidocaine; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rabbits; Strychnine	1972
Some studies on the convulsant action of folic acid. British journal of pharmacology, 1973, Volume: 48, Issue:2 Topics: Alkaloids; Animals; Auditory Threshold; Cerebral Ventricles; Dioxoles; Electroshock; Folic Acid; Folic Acid Antagonists; Glutamates; Injections; Injections, Intravenous; Isoquinolines; Mice; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine	1973
Drug effects on the spontaneous electrical activity of the squid giant axon. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3 Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione	1967
The effects of pentobarbital and related compounds on frog motoneurons. Brain research, 1980, Jun-02, Volume: 191, Issue:1 Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission	1980
Distinction between the effects of barbiturates, benzodiazepines and phenytoin on responses to gamma-aminobutyric acid receptor activation and antagonism by bicuculline and picrotoxin. British journal of pharmacology, 1981, Volume: 73, Issue:3 Topics: Animals; Barbiturates; Benzodiazepines; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Muscimol; Phenytoin; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A	1981
Voltage clamp analysis of inhibitory synaptic action in crayfish stretch receptor neurons. Federation proceedings, 1981, Volume: 40, Issue:11 Topics: Animals; Astacoidea; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channels; Mechanoreceptors; Membrane Potentials; Neural Inhibition; Phenytoin; Picrotoxin; Synapses	1981
RO5-4864, a ligand for benzodiazepine micromolar and peripheral binding sites: antagonism and enhancement of behavioural effects. Psychopharmacology, 1983, Volume: 80, Issue:2 Topics: Animals; Behavior, Animal; Benzodiazepinones; Drug Interactions; Flumazenil; Male; Motor Activity; Phenytoin; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A	1983
Interaction between phenytoin and diazepam in mutant Han-Wistar rats with progressive spastic paresis. Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 321, Issue:1 Topics: Animals; Diazepam; Drug Interactions; Electromyography; Female; Male; Muscle Spasticity; Muscles; Paralysis; Phenytoin; Picrotoxin; Rats; Rats, Mutant Strains; Time Factors	1982
Opposite effects of 5,5-diphenylhydantoin and picrotoxin on GABAergic inhibition in crayfish stretch receptor. Advances in biochemical psychopharmacology, 1981, Volume: 29 Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Mechanoreceptors; Membrane Potentials; Phenytoin; Picrotoxin	1981
Opposing actions of convulsants and anticonvulsants on GABA responses of crayfish stretch receptors. Advances in biochemical psychopharmacology, 1981, Volume: 29 Topics: Animals; Anticonvulsants; Astacoidea; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Phenytoin; Picrotoxin; Synapses	1981
On the action of the anticonvulsant 5,5-diphenylhydantoin and the convulsant picrotoxin in crayfish stretch receptor. The Journal of physiology, 1981, Volume: 315 Topics: Action Potentials; Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Neural Inhibition; Phenytoin; Picrotoxin	1981
Interaction of diphenylhydantoin and benzodiazepines in the CNS. Brain research, 1980, May-05, Volume: 189, Issue:1 Topics: Animals; Brain; Diazepam; Electric Conductivity; Lysergic Acid Diethylamide; Phenytoin; Picrotoxin; Raphe Nuclei; Rats; Receptors, Drug	1980
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents. Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12 Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cimetidine; Diazepam; Female; Mice; Muscimol; Phenobarbital; Phenytoin; Picrotoxin; Receptors, GABA; Seizures; Strychnine	1993
Chemical kindling: implications for antiepileptic drugs - sensitive and resistant epilepsy models. Epilepsia, 1996, Volume: 37, Issue:3 Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Picrotoxin; Rats; Rats, Wistar; Seizures	1996
Chinese herb constituent beta-eudesmol alleviated the electroshock seizures in mice and electrographic seizures in rat hippocampal slices. Neuroscience letters, 1997, Aug-15, Volume: 231, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Electroshock; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenytoin; Picrotoxin; Potassium; Rats; Seizures; Sesquiterpenes, Eudesmane; Terpenes	1997
STIMULANT ACTION OF PYRIDYL DERIVATIVES OF BENZODIOXANS AND BENZODIOXEPANS. International journal of neuropharmacology, 1963, Volume: 2 Topics: Animals; Anticonvulsants; Atropine; Bemegride; Central Nervous System Agents; Central Nervous System Stimulants; Chlorisondamine; Chlorpromazine; Diazepam; Mephenesin; Meprobamate; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Picrotoxin; Research; Seizures; Strychnine; Tranquilizing Agents	1963
Development of a Drosophila seizure model for in vivo high-throughput drug screening. The European journal of neuroscience, 2006, Volume: 24, Issue:8 Topics: Amino Acid Sequence; Animals; Anticonvulsants; Behavior, Animal; Cell Survival; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila; Drug Evaluation, Preclinical; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; Larva; Pentylenetetrazole; Phenotype; Phenytoin; Picrotoxin; Seizures	2006
Phythochemical screening and anticonvulsant activity of Cymbopogon winterianus Jowitt (Poaceae) leaf essential oil in rodents. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:8 Topics: Animals; Anticonvulsants; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mice; Oils, Volatile; Pentylenetetrazole; Phenytoin; Phytotherapy; Picrotoxin; Plant Leaves; Plant Oils; Poaceae; Seizures; Strychnine	2008
Antiulcer and anticonvulsant activity of Croton zambesicus. Pakistan journal of pharmaceutical sciences, 2009, Volume: 22, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Anticonvulsants; Antipsychotic Agents; Central Nervous System Depressants; Convulsants; Croton; Ethanol; Female; Indomethacin; Male; Medicine, African Traditional; Mice; Nigeria; Pentylenetetrazole; Phenytoin; Picrotoxin; Plant Extracts; Plant Roots; Rats; Reserpine; Stomach Ulcer	2009
Anticonvulsant activity of DNS II fraction in the acute seizure models. Journal of ethnopharmacology, 2010, Apr-21, Volume: 128, Issue:3 Topics: Acetone; Animals; Anticonvulsants; Delphinium; Diazepam; Epilepsy; Male; Melanoma; Mice; Mice, Inbred Strains; Pakistan; Pentylenetetrazole; Phenytoin; Picrotoxin; Ranunculaceae; Seizures; Skin Neoplasms	2010
Activity-dependent alternative splicing increases persistent sodium current and promotes seizure. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, May-23, Volume: 32, Issue:21 Topics: Alternative Splicing; Animals; Drosophila Proteins; Exons; gamma-Aminobutyric Acid; Membrane Potentials; Molecular Sequence Data; Mutant Proteins; Phenytoin; Picrotoxin; Ribonucleoproteins; Seizures; Sodium Channels; Synaptic Transmission	2012
Evaluation of anticonvulsant actions of dibromophenyl enaminones using in vitro and in vivo seizure models. PloS one, 2014, Volume: 9, Issue:6 Topics: Action Potentials; Animals; Anticonvulsants; CA1 Region, Hippocampal; Culture Media; Cyclohexanones; Cyclohexylamines; Electric Stimulation; Electroshock; Locomotion; Magnesium; Male; Microtomy; Phenytoin; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Tissue Culture Techniques	2014
Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds. PloS one, 2016, Volume: 11, Issue:2 Topics: 4-Aminopyridine; Adult; Amines; Animals; Anticonvulsants; Antipain; Calcium; Calmodulin; Central Nervous System; Convulsants; Cyclohexanecarboxylic Acids; Dipyridamole; Drosophila melanogaster; Drosophila Proteins; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Larva; Male; Molecular Imaging; Motor Neurons; Phenytoin; Picrotoxin; Primary Cell Culture; Sodium Channels	2016