picrotoxin has been researched along with pentobarbital in 221 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 123 (55.66) | 18.7374 |
| 1990's | 73 (33.03) | 18.2507 |
| 2000's | 19 (8.60) | 29.6817 |
| 2010's | 6 (2.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lothman, EW; Somjen, GG | 1 |
| Krnjević, K; Morris, ME | 1 |
| Dinnedahl, V; Gumulka, SW; Opmeer, FA; Schönhöfer, PS | 1 |
| Barker, JL; Macdonald, RL | 1 |
| Franco, S; Schlosser, W | 1 |
| Wall, PD; Yaksh, TL | 1 |
| Gusel'nikova, KG; Ivanova, LV; Kipor, GV | 1 |
| Nicoll, RA | 1 |
| Liu, CC; Nichols, AC; Snead, OC | 1 |
| Bartolini, A; Ghelardini, C; Giotti, A; Malcangio, M; Malmberg-Aiello, P | 1 |
| Angelotti, TP; MacDonald, RL; Porter, NM; Twyman, RE | 1 |
| Lin, WC; Watanabe, K; Yano, S | 2 |
| Pericić, D; Tvrdeić, A | 1 |
| Arakawa, O; Nakahiro, M; Narahashi, T | 1 |
| Ishibashi, S; Ishii, K; Okazaki, H; Tokuda, H | 1 |
| Allan, AM; Draski, LJ; Mayes, GG | 1 |
| Lindgren, S; Meyerson, B; Westerling, P | 1 |
| Long, SK; van Wilgenburg, H; Wesselman, JP | 1 |
| Araki, Y; Gomita, Y; Ichimaru, Y; Moriyama, M | 1 |
| Kaneko, A; Suzuki, S; Tachibana, M | 1 |
| Baur, R; Malherbe, P; Möhler, H; Sigel, E; Trube, G | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 1 |
| McIntyre, T; Skolnick, P | 1 |
| Kang, T; Xiao-Hong, D; Xin-Quan, J | 1 |
| Georgiev, V; Getova, D; Ivanova, V | 1 |
| Boeijinga, PH; Lopes da Silva, FH; Pennartz, CM | 1 |
| Akaike, N; Nakagawa, T; Nakaye, T; Shirasaki, T; Wakamori, M | 1 |
| Albertson, TE; Joy, RM | 1 |
| Fincher, AS; Frye, GD; Griffith, WH; Lorenzetti, M; Trzeciakowski, J | 1 |
| Baur, R; Malherbe, P; Mohler, H; Persohn, E; Richards, JG; Sigel, E | 1 |
| Friedman, DL; Redburn, DA | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M | 1 |
| Paul, SM; Schwartz, RD; Skolnick, P; Suzdak, PD | 1 |
| Allan, AM; Harris, RA | 1 |
| Holtzman, SG | 1 |
| Macdonald, RL; Rogers, CJ; Twyman, RE | 1 |
| Mienville, JM; Vicini, S | 1 |
| Kettenmann, H; Köhler, M; Lüddens, H; Pritchett, DB; Schofield, PR; Seeburg, PH; Shivers, BD; Sontheimer, H; Werner, P; Ymer, S | 1 |
| Dudek, BC; Phillips, TJ | 1 |
| Baur, R; Peter, AB; Sigel, E; Yao, Y | 1 |
| Paul, SM; Schwartz, RD; Seale, TW; Skolnick, P | 1 |
| Kulkarni, SK; Ticku, MK | 2 |
| Kamei, J; Kasuya, Y; Ogawa, M | 1 |
| Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC | 1 |
| Hara, S; Morioka, S; Satoh, K; Yanagihara, S | 1 |
| Mehta, AK; Ticku, MK | 2 |
| Handley, SL; Heaton, JC; Rea, PJ; Singh, L | 1 |
| Gross, RA; Macdonald, RL; Weddle, MG | 1 |
| McGarrick, JD; Stone, TW; Thexton, AJ | 1 |
| Rastogi, SK; Ticku, MK | 1 |
| Martin, JV; Mendelson, WB; Roseberry, C; Skolnick, P; Squires, R; Wagner, R; Weissman, BA | 1 |
| Chow, SC; Johnston, GA; MacDonald, RL; Prager, RH; Skerritt, JH; Ward, AD | 1 |
| Scholfield, CN; Steel, L | 1 |
| Rastogi, SK; Thyagarajan, R; Ticku, MK | 1 |
| Chweh, AY; Swinyard, EA; Ulloque, RA; Wolf, HH | 1 |
| Jackson, JA; Paul, SM; Schwartz, RD; Skolnick, P; Weigert, D | 1 |
| Simmonds, MA | 1 |
| Culp, S; Liljequist, S; Tabakoff, B | 1 |
| Garcha, HS; Rose, IC; Stolerman, IP | 1 |
| Little, HJ; Nutt, DJ; Taylor, SC | 1 |
| Lindgren, S; Simmonds, MA | 1 |
| Thalmann, RH | 1 |
| Bédard, L; Caron, N; Seoane, JR | 1 |
| Lee, M; Netzeband, JG; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Asami, T; Koizumi, Y; Naruse, T | 1 |
| Akaike, N; Inomata, N; Oyama, Y; Tokutomi, N | 1 |
| Haberly, LB; Tseng, GF | 1 |
| Akaike, N; Maruyama, T; Tokutomi, N | 1 |
| Covey, DF; Ferrendelli, JA; Levine, JA; Naritoku, DK | 1 |
| Mitzdorf, U | 1 |
| Longo, VG; Sagratella, S | 1 |
| Girard, CL; Matte, JJ; Seoane, JR | 1 |
| Fukuda, H; Ito, T; Watanabe, K | 1 |
| Boyd, EH; Boyd, ES; Brown, LE | 1 |
| Franc, Z; Siegelová, J | 1 |
| Dutton, H; Rudomin, P | 1 |
| Banna, NR; Jabbur, SJ | 1 |
| Gorgiladze, GI | 1 |
| Cho, AK; Haslett, WL | 1 |
| Laycock, GM; Shulman, A; Wright, RD | 1 |
| Bean, JW; Thom, B; Zee, D | 1 |
| Chittal, SM; Gokhale, SV; Naik, SR | 1 |
| Buchanan, AS; Laycock, GM; Shulman, A | 1 |
| Absil, J; Buchel, L | 1 |
| Liebl, L; Lux, HD; ten Bruggencate, G | 1 |
| Yoshino, T | 1 |
| Braud, WG; Liu, Y | 1 |
| Hart, JL | 1 |
| Tan, U | 1 |
| Barnes, CD; Herman, EH | 1 |
| Ban, T; Sasa, M; Shimamoto, K; Takaori, S | 1 |
| Dadkar, NK; Damle, SK; Gaitonde, B | 1 |
| Kido, R; Matsushita, A; Takesue, H | 1 |
| Garg, M | 1 |
| Elliott, KA; Yoshino, Y | 3 |
| Feldberg, W; Georgiev, VP | 1 |
| Jaques, LB; Lucas, ON; Millar, GJ | 1 |
| Baker, WW; Benedict, F | 1 |
| Sverdlov, IuS | 1 |
| Tsuchida, Y | 1 |
| Grinnell, AD | 1 |
| Rudomin, P | 1 |
| Garg, M; Holland, HC | 1 |
| Collins, RJ; Simonton, VR | 1 |
| Morgan, WW; Pfeil, KA | 1 |
| Kerr, DI; Ong, J | 1 |
| Kamp, CW; Morgan, WW | 1 |
| Hagiwara, Y; Suzuki, Y; Taguchi, K | 1 |
| Barker, JL; Segal, M | 1 |
| Nicoll, RA; Wojtowicz, JM | 1 |
| Leeb-Lundberg, F; Olsen, RW; Snowman, A | 1 |
| Davis, WC; Ticku, MK | 3 |
| Aickin, CC; Deisz, RA | 1 |
| DeHaven, R; Pong, SS; Wang, CC | 1 |
| Fukuda, H; Matsumoto, K | 1 |
| Johnston, GA; Willow, M | 1 |
| Brenner, O; Quast, U | 1 |
| Burch, TP; Ramanjaneyulu, R; Thyagarajan, R; Ticku, MK | 1 |
| Ashton, D | 1 |
| DiMicco, JA; Gillis, RA; Hamosh, P; Norman, WP; Segal, SA; Williford, DJ; Yamada, KA | 1 |
| Braestrup, C; Honoré, T; Nielsen, M | 1 |
| Dewey, WL; Glennon, RA; Young, R | 1 |
| Ramanjaneyulu, R; Ticku, MK | 1 |
| Carter, RB; Leander, JD | 1 |
| Macdonald, RL; Skerritt, JH | 1 |
| Herling, S; Winger, G | 1 |
| Gormley, JM; Holtman, JR; Richter, JA; Simon, JR | 1 |
| Fukuda, H; Goto, M; Kondo, M | 1 |
| Desarmenien, M; Feltz, P; Headley, PM; Santangelo, F | 1 |
| Burnham, WM; Kalichman, MW; Livingston, KE | 1 |
| Carrer, HF; Ferreyra, H | 1 |
| Collins, GG | 2 |
| Bormann, J; Feigenspan, A | 1 |
| Hiscock, JJ; Mackenzie, L; Medvedev, A; Willoughby, JO | 1 |
| Nabeshima, A; Saito, T; Takahata, N; Toki, S | 1 |
| Ali, BH; Banna, NR; Bashir, AK; Tanira, MO | 1 |
| Bormann, J; Feigenspan, A; Wässle, H | 1 |
| Kelder, D; Ross, SB | 1 |
| Ma, JY; Narahashi, T | 1 |
| Gewiss, MV; Goldberg, SR; Marley, RJ; Schindler, CW; Thorndike, EB | 1 |
| Garau, F; Harris, RA; Sanna, E | 1 |
| Bähring, R; Grantyn, R; Martelli, EA; Standhardt, H | 1 |
| Blackmore, PF; Bleasdale, JE; Im, WB | 1 |
| Cao, B; Hong, GX | 1 |
| Belelli, D; Chen, R; Lambert, JJ; Lan, NC; Peters, JA; Reyes, A | 1 |
| Crosby, G; Goto, T; Marota, JJ | 1 |
| Lukasiewicz, PD; Maple, BR; Werblin, FS | 1 |
| Ho, IK; Ito, Y | 1 |
| Nagata, K; Narahashi, T | 1 |
| Gitter, AH; Möhler, H; Plinkert, PK; Zenner, HP | 1 |
| Abbott, FV; Franklin, KB | 1 |
| Drummer, HL; Hasan, ZA; Tubbs, T; Woolley, DE; Zimmer, L | 1 |
| Smart, TG; Xie, X | 1 |
| Krůsek, J; Vanĕcek, J; Zemková, H | 1 |
| Chang, YF; Gao, XM | 1 |
| Bernardi, MM; Gorniak, SL; Massoco, CO; Silva, MR; Spinosa, MS | 1 |
| Hiscock, JJ; Mackenzie, L; Willoughby, JO | 1 |
| Macdonald, RL; Saxena, NC | 1 |
| Burt, D; Cestari, IN; Li, L; Uchida, I; Yang, J | 1 |
| Fiszer de Plazas, S; Mitridate de Novara, A; Viapiano, MS | 1 |
| Connolly, CN; Moss, SJ; Smart, TG; Wooltorton, JR | 1 |
| Donevan, SD; Rho, JM; Rogawski, MA | 1 |
| Cross, AJ; Green, AR; Misra, A; Murray, TK; Snape, MF | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Belachew, S; Coucke, P; Goffin, F; Lefebvre, PP; Malgrange, B; Moonen, G; Rigo, JM; Van de Water, TR; Xhauflaire, G | 1 |
| Francischi, JN; Pesquero, SM; Salgado, JV; Santana, MA; Tatsuo, MA; Yokoro, CM | 1 |
| Aimi, N; Leewanich, P; Matsumoto, K; Subhadhirasakul, S; Takayama, H; Tohda, M; Watanabe, H | 1 |
| Aspinwall, LS; Bermudez, I; King, LA; Wafford, KA | 1 |
| Bhave, SV; Hoffmann, E; Hoffmann, PL; Olsen, RW; Tabakoff, B; Tobin, AJ; Tyndale, RF | 1 |
| Kaila, K; Lamsa, K | 1 |
| Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J | 1 |
| Heal, DJ; Martin, KF; Phillips, I; Thompson, KS | 1 |
| Dunwiddie, TV; Proctor, WR; Soldo, BL | 1 |
| Alvarez-Hernandez, X; Bueno, OF; Leidenheimer, NJ; Robinson, LC | 1 |
| Ito, Y; Iwatsuki, N; Izumi, H; Karita, K; Sato, M | 1 |
| Autere, AM; Kaila, K; Lamsa, K; Taira, T | 1 |
| Chau, C; Hales, TG; Kaufman, DL; Tian, J | 1 |
| Fiszer de Plazas, S; Mitridate de Novara, AM; Rodríguez Gil, DJ; Viapiano, MS | 1 |
| Chen, CL; Chiu, TH; Yang, YR | 1 |
| Drinyaev, VA; Grichenko, AS; Kokoz, YM; Korystova, AF; Kruglyak, EB; Mosin, VA; Sterlina, TS; Tsyganova, VG; Victorov, AV; Zenchenko, KI | 1 |
| Saxena, NC | 1 |
| Findlay, GS; Harris, RA; Harrison, NL; Ueno, S | 2 |
| Jaako, K; Kaasik, A; Kalda, A; Zharkovsky, A | 1 |
| Benson, JA; Darlison, MG; Forster, IC; Harvey, RJ | 1 |
| Baufreton, J; Bioulac, B; Dovero, S; Dufy, B; Garret, M; Taupignon, A | 1 |
| Huguenard, JR; Jacobsen, RB; Ulrich, D | 1 |
| Aoyagi, Y; Ohta, A; Watanabe, Y; Yamada, K | 1 |
| Archer, DP; Roth, SH; Samanani, N | 1 |
| Du, XM; Guo, YT; Shoyama, Y; Sun, NY; Takizawa, N | 1 |
| Bonnert, TP; Cagetti, E; Thompson, SA; Wafford, KA; Whiting, PJ | 1 |
| Kullmann, DM; Semyanov, A | 1 |
| Menzikov, S; Menzikova, O | 1 |
| Longacher, JM; Staley, KJ; Yee, AS | 1 |
| MAGISTRETTI, MJ; MURMANN, W; SETNIKAR, I | 2 |
| ECCLES, JC; SCHMIDT, R; WILLIS, WD | 1 |
| FISCHER, R; LISS, L; SOLZE, DA | 1 |
| SCHMIDT, RF | 1 |
| LAYCOCK, GM; SHANKLY, KH; SHULMAN, A; WRIGHT, RD | 1 |
| Kim, EM; O'Hare, E; Tierney, KJ | 1 |
| Chang, SM; Ha, JH; Lee, JT; Lee, MG | 1 |
| Avallone, R; Baraldi, M; Brusiani, F; Losi, G; Puia, G; Rivasi, M; Zanoli, P; Zavatti, M | 1 |
| Hall, SD; Stanford, IM; Woodhall, GL; Yamawaki, N | 1 |
| Bremer, F | 1 |
| Czajkowski, C; Jackson, MB; Muroi, Y; Theusch, CM | 1 |
| Simeone, TA; White, HS; Wilcox, KS | 1 |
| Goddard, CA; Huguenard, JR; Knudsen, EI; Sridharan, D | 1 |
| Constantin, S; Herbison, AE; Iremonger, KJ | 1 |
| Chang, CF; Chen, CS; Chuang, TH; Mukkanti, K; Pusuluri, S; Sorra, K; Wu, CR | 1 |
| Czajkowski, C; Ghosh, B; Tsao, TW | 1 |
| Bright, DP; Seljeset, S; Smart, TG; Thomas, P | 1 |
221 other study(ies) available for picrotoxin and pentobarbital
| Article | Year |
|---|---|
Functions of primary afferents and responses of extracellular K+ during spinal epileptiform seizures.
Topics: Action Potentials; Animals; Cats; Extracellular Space; Membrane Potentials; Neural Inhibition; Neurons; Neurons, Afferent; Penicillin G; Pentobarbital; Picrotoxin; Potassium; Seizures; Spinal Cord; Spinal Nerve Roots | 1976 |
Input-output relation of transmission through cuneate nucleus.
Topics: Animals; Blood Pressure; Cats; Decerebrate State; Evoked Potentials; Medulla Oblongata; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission; Temperature | 1976 |
Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain.
Topics: Animals; Atropine; Brain; Brain Chemistry; Convulsants; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Harmaline; Male; Mice; Oxotremorine; Pentobarbital; Pentylenetetrazole; Picrotoxin; Tremor | 1976 |
Different actions of anticonvulsant and anesthetic barbiturates revealed by use of cultured mammalian neurons.
Topics: Action Potentials; Cells, Cultured; Electric Conductivity; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, Neurotransmitter | 1978 |
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines.
Topics: Animals; Benzodiazepines; Bicuculline; Cats; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Pentobarbital; Picrotoxin | 1979 |
Effect of Lissauer tract stimulation on activity in dorsal roots and in ventral roots.
Topics: Action Potentials; Animals; Cats; Electric Stimulation; Naloxone; Neurons, Afferent; Pentobarbital; Picrotoxin; Reflex; Spinal Cord; Spinal Nerve Roots | 1978 |
[A pharmacologic analysis of the slow potential arising in response to adequate stimulation of the frog olfactory bulb].
Topics: Animals; Anura; Chloralose; gamma-Aminobutyric Acid; Membrane Potentials; Morphine; Olfactory Bulb; Penicillins; Pentobarbital; Picrotoxin; Rana temporaria; Strychnine | 1975 |
Pentobarbital: action on frog motoneurons.
Topics: Animals; Anura; Aspartic Acid; Bicuculline; Cell Membrane Permeability; Depression, Chemical; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Motor Neurons; Pentobarbital; Picrotoxin | 1975 |
gamma-Hydroxybutyric acid binding sites: interaction with the GABA-benzodiazepine-picrotoxin receptor complex.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Oxybate; Synaptic Membranes | 1992 |
Desensitization of GABAB receptors and antagonism by CGP 35348, prevent bicuculline- and picrotoxin-induced antinociception.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Tolerance; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Mice; Motor Activity; Organophosphorus Compounds; Pain Measurement; Pentobarbital; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Kinetic properties of alpha 1 beta 1 gamma-aminobutyric acidA receptor channels expressed in Chinese hamster ovary cells: regulation by pentobarbital and picrotoxin.
Topics: Animals; Chloride Channels; Chlorides; CHO Cells; Cricetinae; Ion Channel Gating; Kinetics; Membrane Potentials; Membrane Proteins; Models, Biological; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins | 1992 |
Involvement of central GABAA receptor complex in controlling the basal gastric secretory activity in pylorus-ligated rats.
Topics: Analysis of Variance; Anesthesia; Animals; Bicuculline; Diazepam; Gastric Acid; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Dihydroergotoxine modulation of the GABAA receptor-associated Cl- ionophore in mouse brain.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Dihydroergotoxine; Drug Synergism; Female; Ionophores; Membrane Proteins; Mice; Mice, Inbred CBA; Pentobarbital; Picrotoxin; Receptors, GABA-A | 1992 |
Chloride current induced by alcohols in rat dorsal root ganglion neurons.
Topics: Alcohols; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Picrotoxin; Rats; Structure-Activity Relationship | 1992 |
Barbiturates suppress glucose utilization by inhibition of hexokinase in neuroblastoma cells.
Topics: 3-O-Methylglucose; Barbiturates; Biological Transport; Cell Line; Deoxyglucose; gamma-Aminobutyric Acid; Hexokinase; Humans; Kinetics; Methylglucosides; Neuroblastoma; Pentobarbital; Picrotoxin; Tumor Cells, Cultured | 1992 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Muscimol; Pentobarbital; Phenobarbital; Phenotype; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Selection, Genetic | 1991 |
Functional changes in GABAA receptor stimulation during the oestrous cycle of the rat.
Topics: Animals; Chlorides; Estrogens; Estrus; Female; Flurazepam; In Vitro Techniques; Neurons, Afferent; Ovariectomy; Pentobarbital; Picrotoxin; Potassium; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
The effects of pentobarbital and benzodiazepines on GABA-responses in the periphery and spinal cord in vitro.
Topics: Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Male; Pentobarbital; Peripheral Nerves; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synapses; Vagus Nerve | 1991 |
Effects of anxiolytic drugs on escape behavior induced by dorsal central gray stimulation in rats.
Topics: Animals; Anti-Anxiety Agents; Arousal; Avoidance Learning; Bicuculline; Brain Mapping; Bromazepam; Chlordiazepoxide; Diazepam; Electric Stimulation; Escape Reaction; GABA Antagonists; Male; Meprobamate; Pentobarbital; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains; Sensory Thresholds | 1991 |
Effects of glycine and GABA on isolated bipolar cells of the mouse retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Mice; Neurons; Pentobarbital; Picrotoxin; Potassium; Retina; Sodium; Strychnine | 1990 |
The effect of subunit composition of rat brain GABAA receptors on channel function.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Carbolines; Dactinomycin; Diazepam; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Xenopus | 1990 |
Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.
Topics: Animals; Baclofen; Bicuculline; Cattle; Cerebral Cortex; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression; Membrane Potentials; Oocytes; Pentobarbital; Picrotoxin; Poly A; Rats; Receptors, GABA-A; Retina; RNA; RNA, Messenger; Transfection; Xenopus | 1991 |
t-[35S]butylbicyclophosphorothionate binding under equilibrium and nonequilibrium conditions: differential effects of barbiturates and gamma-aminobutyric acid in the long-sleep and short-sleep selected mouse lines.
Topics: Animals; Barbiturates; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Cerebral Cortex; Chloride Channels; Ethanol; gamma-Aminobutyric Acid; Kinetics; Male; Membrane Proteins; Mice; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Sleep | 1991 |
Pentobarbital selectively blocks supraspinal morphine analgesia. Evidence for GABAA receptor involvement.
Topics: Analgesia; Animals; Diazepam; Drug Synergism; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Muscimol; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord | 1990 |
Investigation of 2-hydroxylamino-5-ethyl-5-sec-pentylbarbituric acid for anxyolitic action.
Topics: Animals; Anti-Anxiety Agents; Conflict, Psychological; Male; Pentobarbital; Phenobarbital; Picrotoxin; Prohibitins; Rats | 1990 |
Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Axons; Dipeptides; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Neurotoxins; Nucleus Accumbens; Pentobarbital; Picrotoxin; Pyridostigmine Bromide; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Time Factors; Tubocurarine | 1990 |
gamma-Aminobutyric acid-induced response in acutely isolated nucleus solitarii neurons of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Penicillin G; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1991 |
Interactions of GABAA antagonists with deltamethrin, diazepam, pentobarbital, and SKF100330A in the rat dentate gyrus.
Topics: Action Potentials; Animals; Anticonvulsants; Bicuculline; Diazepam; Drug Interactions; Female; GABA Antagonists; Hippocampus; Insecticides; Male; Membrane Potentials; Nicotinic Acids; Nitriles; Pentobarbital; Picrotoxin; Pyrethrins; Rats; Rats, Inbred Strains | 1991 |
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Taurine; Tetrodotoxin | 1990 |
Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Brain; Cloning, Molecular; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Oocytes; Organ Specificity; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; RNA, Messenger; Xenopus laevis | 1990 |
Evidence for functionally distinct subclasses of gamma-aminobutyric acid receptors in rabbit retina.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Binding, Competitive; Cell Fractionation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Light; Models, Theoretical; Pentobarbital; Picrotoxin; Rabbits; Receptors, GABA-A; Retina | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; gamma-Aminobutyric Acid; Male; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Inbred Strains | 1990 |
Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.
Topics: Animals; Bicuculline; Biological Transport; Brain; Cell-Free System; Chlorides; Ethanol; In Vitro Techniques; Ion Channels; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Synaptosomes | 1986 |
Anesthetic and convulsant barbiturates alter gamma-aminobutyric acid-stimulated chloride flux across brain membranes.
Topics: Animals; Barbiturates; Brain; Chlorides; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred DBA; Pentobarbital; Picrotoxin; Receptors, GABA-A; Stereoisomerism | 1986 |
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1986 |
Pentobarbital and picrotoxin have reciprocal actions on single GABAA receptor channels.
Topics: Action Potentials; Animals; Cells, Cultured; Ion Channels; Membrane Potentials; Mice; Pentobarbital; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1989 |
Pregnenolone sulfate antagonizes GABAA receptor-mediated currents via a reduction of channel opening frequency.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorides; Ion Channels; Membrane Potentials; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnenolone; Rats; Receptors, GABA-A | 1989 |
Molecular studies of the GABAA receptor.
Topics: Amino Acid Sequence; Animals; Cell Line; DNA; Gene Expression Regulation; Ion Channels; Multigene Family; Pentobarbital; Picrotoxin; Protein Conformation; Receptors, GABA-A; Xenopus | 1989 |
Genotype-dependent effects of GABAergic agents on sedative properties of ethanol.
Topics: Animals; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Genetics, Behavioral; Genotype; Hypnotics and Sedatives; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Muscimol; Pentobarbital; Picrotoxin; Species Specificity | 1989 |
The tremorigen aflatrem is a positive allosteric modulator of the gamma-aminobutyric acidA receptor channel expressed in Xenopus oocytes.
Topics: Allosteric Regulation; Animals; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Indoles; Membrane Proteins; Mycotoxins; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Xenopus | 1989 |
Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Dose-Response Relationship, Drug; Frontal Lobe; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Species Specificity; Synaptosomes | 1989 |
Interaction between GABAergic anticonvulsants and the NMDA receptor antagonist MK 801 against MES- and picrotoxin-induced convulsions in rats.
Topics: Animals; Anticonvulsants; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Electroshock; Ethanol; Male; Motor Activity; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Stereotyped Behavior | 1989 |
Effects of GABA antagonists on the pentobarbital-induced depression of respiration and cough in rats.
Topics: Animals; Bicuculline; Cough; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reflex; Respiration; Strychnine | 1989 |
RO15-4513 but not FG-7142 reverses anticonvulsant effects of ethanol against bicuculline- and picrotoxin-induced convulsions in rats.
Topics: Affinity Labels; Animals; Appetite Depressants; Azides; Benzodiazepines; Bicuculline; Carbolines; Ethanol; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1989 |
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1988 |
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Indomethacin; Male; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Taurine | 1988 |
Interactions of pentobarbital and phenobarbital with GABAergic drugs against chemoconvulsants in rats.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Diazepam; Drug Interactions; Isoxazoles; Male; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Strychnine | 1988 |
Involvement of noradrenaline in potentiation of the head-twitch response by GABA-related drugs.
Topics: Adrenergic beta-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Diazepam; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; Male; Methoxydimethyltryptamines; Metoprolol; Mice; Muscimol; Norepinephrine; Pentobarbital; Picrotoxin; Stereotyped Behavior; Taurine | 1986 |
Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Bicuculline; Carbolines; Cells, Cultured; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Nitrazepam; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1986 |
Pharmacologically induced changes in the latency of digastric reflexes in 1-7 day old rabbits.
Topics: Animals; Animals, Newborn; Bicuculline; Decerebrate State; Diazepam; Electromyography; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rabbits; Reflex; Stomach; Strychnine; Synaptic Transmission | 1988 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
Are the toxicities of pentobarbital and ethanol mediated by the GABA-benzodiazepine receptor-chloride ionophore complex?
Topics: Animals; Chlorides; Ethanol; Ionophores; Ketamine; Male; Mice; Organophosphorus Compounds; Pentobarbital; Picrotoxin; Pyrazoles; Receptors, GABA-A; Reflex; Strychnine | 1985 |
Differential modulation of gamma-aminobutyric acid receptors by caprolactam derivatives with central nervous system depressant or convulsant activity.
Topics: Animals; Azepines; Caprolactam; Central Nervous System; Central Nervous System Depressants; Convulsants; Male; Muscle Relaxants, Central; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sesterterpenes; Structure-Activity Relationship | 1985 |
gamma-Aminobutyric acid partly mediates the pentobarbitone depression of synaptic excitation in the guinea-pig olfactory cortex in vitro.
Topics: Animals; Bicuculline; Drug Interactions; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Limbic System; Male; Membrane Potentials; Olfactory Pathways; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1985 |
Separate site(s) of action of optical isomers of 1-methyl-5-phenyl-5-propylbarbituric acid with opposite pharmacological activities at the GABA receptor complex.
Topics: Animals; Anticonvulsants; Brain; Convulsants; In Vitro Techniques; Kinetics; Male; Pentobarbital; Phenobarbital; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stereoisomerism; Time Factors | 1985 |
Effect of picrotoxinin on benzodiazepine receptor binding.
Topics: Animals; Brain; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1985 |
Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes.
Topics: Amobarbital; Animals; Barbiturates; Bicuculline; Brain; Cell Membrane Permeability; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Hexobarbital; Male; Mephobarbital; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Rubidium; Secobarbital; Synapses | 1985 |
Antagonism of flurazepam and other effects of Ro15-1788, PK8165 and Ro5-4864 on the GABA-A receptor complex in rat cuneate nucleus.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Drug Synergism; Flumazenil; Flurazepam; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Pentobarbital; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Effect of ethanol on the binding of 35S-T-butylbicyclophosphorothionate to mouse brain membranes.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cell Membrane; Cerebellum; Cerebral Cortex; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Picrotoxin; Receptors, GABA-A | 1986 |
Midazolam cue in rats: effects of Ro 15-1788 and picrotoxin.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Nicotine; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1986 |
The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.
Topics: Animals; Bicuculline; Body Temperature; Carbolines; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1986 |
Comparison of anticonvulsant effect of pentobarbital and phenobarbital against seizures induced by maximal electroshock and picrotoxin in rats.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Anticonvulsants; Bicuculline; Electroshock; Male; Muscimol; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1986 |
Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Ethanolamines; Flurazepam; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Pentobarbital; Picrotoxin; Potassium; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Blockade of a late inhibitory postsynaptic potential in hippocampal CA3 neurons in vitro reveals a late depolarizing potential that is augmented by pentobarbital.
Topics: Animals; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Pertussis Toxin; Picrotoxin; Rats; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Comparison between pentobarbital- and muscimol-induced feeding in satiated sheep.
Topics: Aminocaproates; Animals; Calcium; Eating; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep; Sodium; Vigabatrin | 1988 |
Pentobarbital augments serotonin-mediated inhibition of cerebellar Purkinje cells.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Male; Neural Inhibition; Pentobarbital; Pentylenetetrazole; Picrotoxin; Purkinje Cells; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Effects of naloxone and picrotoxin on diazepam- or pentobarbital-induced hyperphagia in nondeprived rats.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Feeding Behavior; Hyperphagia; Male; Naloxone; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Intracellular picrotoxin blocks pentobarbital-gated Cl- conductance.
Topics: Animals; Chlorides; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Microinjections; Pentobarbital; Picrotoxin; Rana catesbeiana | 1988 |
Characterization of synaptically mediated fast and slow inhibitory processes in piriform cortex in an in vitro slice preparation.
Topics: Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Picrotoxin; Potassium; Rats; Reaction Time; Synapses | 1988 |
Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation.
Topics: 3-Mercaptopropionic Acid; Anesthesia; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Male; Pentobarbital; Pentylenetetrazole; Perfusion; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurons, Afferent; Pentobarbital; Picrotoxin; Rana catesbeiana | 1987 |
Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on GABA-mediated chloride uptake.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cerebral Cortex; Chlorides; Convulsants; Female; Furans; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Structure-Activity Relationship | 1987 |
Properties of the evoked potential generators: current source-density analysis of visually evoked potentials in the cat cortex.
Topics: Animals; Cats; Evoked Potentials, Visual; Motion Perception; Pentobarbital; Photic Stimulation; Picrotoxin; Synapses; Visual Cortex; Visual Pathways; Visual Perception | 1987 |
An EEG investigation on the role of cerebello-rubral system in the effects of diazepam and pentobarbital.
Topics: Animals; Benzodiazepinones; Cerebellum; Diazepam; Electroencephalography; Female; Flumazenil; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rabbits; Red Nucleus | 1985 |
Studies of the role of gamma-aminobutyric acid in the hypothalamic control of feed intake in sheep.
Topics: Animals; Bicuculline; Brain; Eating; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep | 1985 |
Effect of lyoniol-A on decerebrate rigidity and electroencephalogram in rats.
Topics: Amygdala; Animals; Brain; Caudate Nucleus; Cerebral Decortication; Chlorpromazine; Diterpenes; Electroencephalography; Electromyography; Ethers, Cyclic; Hippocampus; Hypothalamus; Limbic System; Male; Mephenesin; Motor Cortex; Pentobarbital; Pentylenetetrazole; Picrotoxin; Polycyclic Compounds; Rats; Strychnine; Toxins, Biological | 1972 |
The effects of some drugs on an evoked response sensitive to tetrahydrocannabinols.
Topics: Animals; Atropine; Blood Pressure; Brain; Cannabis; Cerebral Cortex; Chloralose; Chlorpromazine; Decerebrate State; Dextroamphetamine; Dronabinol; Electroencephalography; Ethanol; Evoked Potentials; Gallamine Triethiodide; Haplorhini; Lysergic Acid Diethylamide; Male; Mescaline; Methoxamine; Norepinephrine; Pentobarbital; Pentylenetetrazole; Phencyclidine; Picrotoxin; Strychnine | 1974 |
[Afferent circulatory responses of the greater splanchnic nerve and conditions of their reversal in cats].
Topics: Anesthesia, General; Animals; Blood Pressure; Cats; Cordotomy; Electric Stimulation; Hypothermia, Induced; Methods; Neurons, Afferent; Pentobarbital; Periodicity; Picrotoxin; Splanchnic Nerves | 1971 |
Effects of conditioning afferent volleys on variability of monosynaptic responses of extensor motoneurons.
Topics: Analysis of Variance; Animals; Asphyxia; Cats; Computers, Analog; Electric Stimulation; Electrophysiology; Motor Neurons; Muscle Spindles; Neural Conduction; Pentobarbital; Picrotoxin; Reflex; Strychnine; Synapses; Synaptic Transmission; Time Factors | 1969 |
Pharmacological studies on inhibition in the cuneate nucleus of the cat.
Topics: Action Potentials; Animals; Cats; Electric Stimulation; Medulla Oblongata; Nerve Endings; Pentobarbital; Picrotoxin; Strychnine; Synapses; Synaptic Transmission | 1969 |
[Interrelations of vestibular nuclei in the cat medulla oblongata].
Topics: Animals; Benactyzine; Cats; Ear, Inner; Electric Stimulation; Hot Temperature; Medulla Oblongata; Neural Pathways; Pentobarbital; Picrotoxin; Strychnine; Synaptic Transmission; Vestibular Nuclei | 1969 |
The pharmacological properties of 2,2-bis-(3',4'-dimethoxyphenyl)-N-methyl-N-propargyl ethylamine (BAEA).
Topics: Animals; Blood Pressure; Cats; Electroencephalography; Ganglionic Blockers; Heart; Hypnotics and Sedatives; Mice; Neuromuscular Junction; Pentobarbital; Pentylenetetrazole; Picrotoxin; Strychnine | 1965 |
Hypnotic-analeptic interaction at different neural levels in cats and rabbits.
Topics: Animals; Bemegride; Cats; Central Nervous System; Central Nervous System Stimulants; Decerebrate State; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rabbits | 1965 |
Pulmonary changes with convulsions induced by drugs and oxygen at high pressure.
Topics: Amino Alcohols; Animals; Central Nervous System Stimulants; Chlorpromazine; Curare; Dibenzylchlorethamine; Hyperbaric Oxygenation; Lung; Oxygen; Pentobarbital; Pentylenetetrazole; Picrotoxin; Pulmonary Edema; Rats; Seizures; Sympatholytics | 1966 |
Effect of analeptics on brain pentobarbital levels and sleeping time in mice.
Topics: Animals; Brain Chemistry; Central Nervous System Stimulants; Female; Mice; Nikethamide; Pentobarbital; Pentylenetetrazole; Picrotoxin; Sleep; Time Factors | 1969 |
Action of central nervous system stimulant and depressant drugs in the intact animal. 4. Surface activity of drugs with central stimulant depressant, or dual stimulant-depressant action.
Topics: Air; Amobarbital; Barbiturates; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Depression, Chemical; Glutarates; Hypnotics and Sedatives; Oxazines; Pentobarbital; Pentylenetetrazole; Phenytoin; Picrotoxin; Pregnanediones; Solutions; Stimulation, Chemical; Surface Properties; Surface Tension; Trimethadione | 1969 |
[Effects of picrotoxin and pentetrazol on experimental sleep in the mouse].
Topics: Animals; Brain Chemistry; Chloral Hydrate; Chlormethiazole; Hexobarbital; Pentobarbital; Pentylenetetrazole; Picrotoxin; Sleep; Time Factors | 1974 |
Possible relationships between extracellular potassium activity and presynaptic inhibition in the spinal cord of the cat.
Topics: Animals; Cats; Electric Stimulation; Electrodes, Implanted; Evoked Potentials; Extracellular Space; Female; Male; Membrane Potentials; Microelectrodes; Neural Inhibition; Neurons; Neurons, Afferent; Pentobarbital; Peripheral Nerves; Picrotoxin; Potassium; Spinal Cord; Synapses | 1974 |
[Action of cardiazol on electrical activity of the spinal cord (spontaneous and evoked potentials)-cardiazol as an antagonist of pentobarbital].
Topics: Action Potentials; Animals; Bemegride; Cats; Evoked Potentials; Female; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Spinal Cord; Spinal Nerve Roots | 1973 |
Modification of learning and memory in goldfish through the use of stimulant and depressant drugs.
Topics: Animals; Avoidance Learning; Cyprinidae; Injections; Memory; Pentobarbital; Picrotoxin; Time Factors | 1974 |
Effects of hyperbaric conditions on the responses of animals to central nervous system stimulants and depressants.
Topics: Animals; Atmospheric Pressure; Body Temperature; Caffeine; Cats; Dose-Response Relationship, Drug; Guinea Pigs; Lethal Dose 50; Mice; Pentobarbital; Picrotoxin; Rats; Sleep; Time Factors | 1974 |
Effects of picrotoxin on the spinal reflexes and their post-tetanic potentiations.
Topics: Alkaloids; Animals; Cats; Depression, Chemical; Imipramine; Indoles; Lumbosacral Plexus; Neuromuscular Junction; Pentobarbital; Picrotoxin; Reflex; Reflex, Monosynaptic; Spinal Cord | 1971 |
Drug modificiation of the Schiff-Sherrington phenomenon.
Topics: Amphetamine; Animals; Cats; Chlorpromazine; Cordotomy; Electromyography; Motor Neurons; Neuromuscular Junction; Pentobarbital; Phenoxybenzamine; Picrotoxin; Reflex; Reserpine; Spinal Cord; Thoracic Vertebrae | 1967 |
The central action of gamma-butyrolactone and gamma-hydroxybutyrate.
Topics: Analysis of Variance; Animals; Behavior, Animal; Butyrates; Central Nervous System; Electric Stimulation; Electroencephalography; Electroshock; Female; Hippocampus; Hydroxybutyrates; Injections, Intraperitoneal; Injections, Intravenous; Lactones; Male; Mice; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rabbits; Rats; Respiration; Reticular Formation; Semicarbazides; Sleep; Strychnine | 1967 |
The convulsive action of 2,5-dicarbethoxy 3,4-dihydroxythiophane (dicetol).
Topics: Acetylcholine; Animals; Blood Pressure; Brain Chemistry; Cats; Depression, Chemical; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Mice; Muscles; Pentobarbital; Picrotoxin; Rabbits; Rats; Reserpine; Respiration; Seizures; Sleep; Thiophenes | 1968 |
Effects of bulbocapnine on spinal reflexes of anesthetized and spinal rats.
Topics: Action Potentials; Alkaloids; Anesthesia; Animals; Aporphines; Depression, Chemical; Male; Motor Neurons; Pentobarbital; Picrotoxin; Rats; Reflex; Reflex, Monosynaptic; Spinal Cord; Strychnine; Tranquilizing Agents | 1970 |
The effects of some central nervous system stimulant and depressant drugs on rearing activity in rats.
Topics: Analysis of Variance; Animals; Breeding; Emotions; Female; Male; Motor Activity; Nicotine; Pentobarbital; Picrotoxin; Rats; Sex Factors; Time Factors | 1969 |
Incorporation of carbon atoms from glucose into free amino acids in brain under normal and altered conditions.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Autoanalysis; Brain; Carbon Isotopes; Depression, Chemical; Glucose; Glutamates; Glutamine; Glycolates; Hypoxia; Injections, Intravenous; Lactates; Male; Metabolism; Methods; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stimulation, Chemical; Time Factors | 1970 |
Effects of various conditions on the movement of carbon atoms derived from glucose into and out of protein in rat brain.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Brain; Carbon Isotopes; Cerebral Cortex; Depression, Chemical; Glucose; Glutamates; Hypoxia; Injections, Intravenous; Insulin; Male; Metabolism; Nerve Tissue Proteins; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stimulation, Chemical; Time Factors | 1970 |
Protein-bound amide groups in brain.
Topics: Amides; Ammonia; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Glucose; Glutamates; Glutamine; Hydrochloric Acid; Nerve Tissue Proteins; Pentobarbital; Peptide Hydrolases; Picrotoxin; Protein Binding; Rats; Seizures; Streptomyces | 1970 |
Central effects of picrotoxin when acting from the liquor spaces in anaesthetized cats.
Topics: Action Potentials; Anesthesia, General; Animals; Body Temperature; Brain; Cats; Cerebral Ventricles; Cervical Vertebrae; Cisterna Magna; Female; Male; Motor Activity; Nicotine; Norepinephrine; Pentobarbital; Perfusion; Picrotoxin; Spinal Cord; Tubocurarine | 1970 |
Spontaneous hemorrhage in anticoagulant-treated rats when subjected to excitant or depressant drugs.
Topics: Animals; Anticoagulants; Barbiturates; Blood Coagulation; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Drug Synergism; Hemorrhage; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Stimulation, Chemical; Stress, Physiological | 1967 |
Differential responses of hippocampal repetitive discharges to scopolamine and pentobarbital.
Topics: Action Potentials; Animals; Carbachol; Cats; Hippocampus; Isoflurophate; Parasympathetic Nervous System; Pentobarbital; Picrotoxin; Scopolamine; Tubocurarine | 1968 |
[Pharmacological study of the role of depolarization of dorsal root fibers in long-lasting inhibition of flexor monosynaptic reflexes].
Topics: Animals; Cats; Electric Stimulation; Motor Neurons; Muscles; Pentobarbital; Picrotoxin; Reflex; Skin; Spinal Nerves; Strychnine; Synapses | 1968 |
[Effects of intravitreous injection of several chemicals on the ERG and the light-induced optic nerve potential in the albino rabbit].
Topics: Action Potentials; Animals; Cyanides; Electroretinography; Injections, Intravenous; Lidocaine; Light; Optic Nerve; Pentobarbital; Picrotoxin; Potassium Chloride; Rabbits; Strychnine; Tetrodotoxin; Vitreous Body | 1968 |
A study of the interaction between motoneurones in the frog spinal cord.
Topics: Animals; Anura; Calcium; Electric Stimulation; Electrophysiology; Hexamethonium Compounds; Magnesium; Motor Neurons; Parasympatholytics; Pentobarbital; Picrotoxin; Spinal Cord; Tubocurarine | 1966 |
Pharmacological evidence for the existence of interneurons mediating primary afferent depolarization in the solitary tract nucleus of the cat.
Topics: Animals; Cats; Electric Stimulation; Medulla Oblongata; Mephenesin; Neural Conduction; Neurons; Pentobarbital; Picrotoxin; Synapses | 1966 |
Consolidation and maze learning: a comparison of several post-trial treatments.
Topics: Animals; Behavior, Animal; Female; Injections, Intraperitoneal; Learning; Male; Nicotine; Pentobarbital; Picrotoxin; Rats | 1967 |
Inhibition of evoked potentials by caudate stimulation and its antagonism by centrally acting drugs.
Topics: Amphetamine; Amygdala; Animals; Bemegride; Caffeine; Cats; Caudate Nucleus; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electrophysiology; Evoked Potentials; Forelimb; Hippocampus; Hypothalamus; Imipramine; Medulla Oblongata; Mephenesin; Morphine; Neurons; Pentobarbital; Pentylenetetrazole; Picrotoxin; Reticular Formation; Strychnine; Thalamus | 1967 |
Depression of cerebellar cGMP by barbiturates. Relationship to locomotor activity.
Topics: Animals; Barbital; Barbiturates; Cerebellum; Cyclic AMP; Dose-Response Relationship, Drug; Male; Motor Activity; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Potentiation of GABAA-receptor-mediated responses by barbiturates in the guinea-pig ileum.
Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1984 |
Some barbiturates enhance the effect of muscimol on dopamine turnover in the rat retina.
Topics: Animals; Barbital; Barbiturates; Convulsants; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Light; Male; Methyltyrosines; Muscimol; Oxazoles; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Retina; Sesterterpenes | 1980 |
Influences on drugs on evoked potentials in the cat cerebellum: I. Effects of CNS depressants and stimulants on the cerebellar afferent pathways.
Topics: Animals; Caffeine; Cats; Central Nervous System Depressants; Central Nervous System Stimulants; Cerebellum; Chlorpromazine; Evoked Potentials; Female; Male; Meprobamate; Neural Pathways; Pentobarbital; Picrotoxin; Strychnine | 1982 |
Rat hippocampal neurons in culture: voltage-clamp analysis of inhibitory synaptic connections.
Topics: Animals; Chlorides; Culture Techniques; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Ion Channels; Kinetics; Membrane Potentials; Neural Inhibition; Neurons; Pentobarbital; Picrotoxin; Rats; Reaction Time; Synapses | 1984 |
The effects of pentobarbital and related compounds on frog motoneurons.
Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission | 1980 |
Barbiturate receptor sites are coupled to benzodiazepine receptors.
Topics: Animals; Anions; Barbiturates; Brain; Kinetics; Pentobarbital; Picrotoxin; Rats; Receptors, Drug; Receptors, GABA-A; Structure-Activity Relationship | 1980 |
Evidence that ethanol and pentobarbital enhance [3H]diazepam binding at the benzodiazepine-GABA receptor-ionophore complex indirectly.
Topics: Animals; Diazepam; Ethanol; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1981 |
Pentobarbital enhances [3H]diazepam binding to soluble receptors at the benzodiazepine--GABA-receptor-ionophore complex.
Topics: Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; In Vitro Techniques; Ionophores; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1981 |
Picrotoxinin and diazepam bind to two distinct proteins: further evidence that pentobarbital may act at the picrotoxinin site.
Topics: Animals; Brain; Cell Membrane; Diazepam; Kinetics; Male; Molecular Weight; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Sesterterpenes | 1981 |
Pentobarbitone interference with inhibitory synaptic transmission in crayfish stretch receptor neurones.
Topics: Animals; Astacoidea; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Neural Inhibition; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1981 |
A comparative study of avermectin B1a and other modulators of the gamma-aminobutyric acid receptor . chloride ion channel complex.
Topics: Animals; Anthelmintics; Benzodiazepines; Brain; Chlorides; Clonazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Male; Pentobarbital; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptic Membranes | 1982 |
Anisatin modulation of GABA- and pentobarbital-induced enhancement of diazepam binding in rat brain.
Topics: Animals; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lactones; Male; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Sesquiterpenes; Sesterterpenes; Spiro Compounds | 1982 |
Enhancement of GABA binding by pentobarbitone.
Topics: Animals; Brain; Cell Membrane; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptosomes | 1980 |
Modulation of [3H]muscimol binding in rat cerebellar and cerebral cortical membranes by picrotoxin, pentobarbitone, and etomidate.
Topics: Animals; Cell Membrane; Cerebellar Cortex; Cerebral Cortex; Etomidate; Imidazoles; Kinetics; Male; Muscimol; Organ Specificity; Oxazoles; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Barbiturate interactions with benzodiazepine-GABA receptor-ionophore complex.
Topics: Animals; Barbiturates; Etomidate; In Vitro Techniques; Ionophores; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes | 1983 |
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
Central gamma-aminobutyric acid involvement in blood pressure control.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Hypertension; Medulla Oblongata; Pentobarbital; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Respiration | 1984 |
Binding of 3H-DMCM to benzodiazepine receptors; chloride dependent allosteric regulation mechanisms.
Topics: Animals; Anions; Carbolines; Cerebral Cortex; Chlorides; Etomidate; Indoles; Molecular Conformation; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes | 1983 |
Stereoselective stimulus effects of 3-methylflunitrazepam and pentobarbital.
Topics: Animals; Benzodiazepinones; Discrimination Learning; Flumazenil; Generalization, Stimulus; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism | 1984 |
Binding characteristics and interactions of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Convulsants; Diazepam; Etomidate; gamma-Aminobutyric Acid; Male; Membranes; Pentobarbital; Picrotoxin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Sesterterpenes | 1984 |
Comparison of the effects of naloxone and picrotoxin on schedule-controlled responding in the pigeon: possible GABA-antagonistic effects of naloxone.
Topics: Animals; Clonazepam; Columbidae; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; GABA Antagonists; Male; Naloxone; Pentobarbital; Picrotoxin | 1984 |
Multiple actions of convulsant barbiturates on mouse neurons in cell culture.
Topics: Action Potentials; Animals; Barbiturates; Cadmium; Calcium; Cells, Cultured; Convulsants; Ganglia, Spinal; Mice; Neurons; Pentobarbital; Picrotoxin; Spinal Cord; Tetrodotoxin | 1984 |
Selective blockade of the discriminative stimulus effects of pentobarbital in pigeons.
Topics: Animals; Bemegride; Columbidae; Discrimination, Psychological; GABA Antagonists; Pentobarbital; Pentylenetetrazole; Picrotoxin; Stimulation, Chemical | 1981 |
High-affinity choline uptake in the hippocampus: its relationship to the physiological state produced by administration of barbiturates and other treatments.
Topics: Animals; Barbiturates; Bicuculline; Choline; Convulsants; Hippocampus; Kinetics; Male; Mice; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Septum Pellucidum; Synaptosomes | 1982 |
Effects of barbiturates on the decerebrate rigidity in rats.
Topics: Aminooxyacetic Acid; Amobarbital; Animals; Barbiturates; Decerebrate State; Male; Mephobarbital; Muscle Rigidity; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Direct action of pentobarbitone in potentiating the responses to GABA of rat dorsal root ganglion neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons; Pentobarbital; Picrotoxin; Rats | 1981 |
Pharmacological investigation of gamma aminobutyric acid (GABA) and the development of amygdala-kindled seizures in the rat.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Aminocaproates; Amygdala; Animals; Bicuculline; gamma-Aminobutyric Acid; Imidazoles; Kindling, Neurologic; Male; Pentobarbital; Picrotoxin; Rats; Seizures; Vigabatrin | 1981 |
Anesthetic-dependent excitability changes in the hypothalamic ventromedial nucleus of the rat.
Topics: Amygdala; Animals; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Middle; Neural Inhibition; Neural Pathways; Neurons; Pentobarbital; Picrotoxin; Rats; Urethane | 1980 |
Release of endogenous amino acid neurotransmitter candidates from rat olfactory cortex slices: possible regulatory mechanisms and the effects of pentobarbitone.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Male; Muscimol; Olfactory Bulb; Pentobarbital; Picrotoxin; Rats; Taurine | 1980 |
Effects of pentobarbitone on the synaptically evoked release of the amino acid neurotransmitter candidates aspartate and GABA from rat olfactory cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Olfactory Pathways; Pentobarbital; Picrotoxin; Rats; Synapses; Taurine | 1981 |
Differential pharmacology of GABAA and GABAC receptors on rat retinal bipolar cells.
Topics: Animals; Bicuculline; Binding Sites; Cells, Cultured; Chickens; Chloride Channels; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; GABA-A Receptor Antagonists; Hexachlorocyclohexane; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Retina; Sesterterpenes; Signal Transduction | 1994 |
Distribution of Fos-positive neurons in cortical and subcortical structures after picrotoxin-induced convulsions varies with seizure type.
Topics: Animals; Behavior, Animal; Cell Count; Cerebral Cortex; Coloring Agents; Electroencephalography; Immunohistochemistry; Infusions, Intravenous; Male; Neurons; Pentobarbital; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Seizures | 1995 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Central nervous system activity of Rhazya stricta (Decne) in mice.
Topics: Abdomen; Analgesia; Animals; Behavior, Animal; Body Temperature; Central Nervous System; Cimetidine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Hypnotics and Sedatives; Male; Medicine, Arabic; Mice; Motor Activity; Naloxone; Pentobarbital; Picrotoxin; Plant Extracts; Plant Leaves; Plants, Medicinal; Seizures; Sleep; Tail | 1995 |
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine | 1993 |
Counteraction of the rapid tolerance to 8-OH-DPAT-induced corticosterone secretion in rats by activation of the GABAA receptor-chloride channel complex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepines; Bicuculline; Chloride Channels; Chlormethiazole; Corticosterone; Drug Tolerance; Ion Channels; Male; Membrane Proteins; Muscimol; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1993 |
Enhancement of gamma-aminobutyric acid-activated chloride channel currents by lanthanides in rat dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Metals, Rare Earth; Neurons; Penicillins; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Terbium; Zinc | 1993 |
GABA receptor-linked chloride channels and the behavioral effects of naltrexone in rats.
Topics: Animals; Behavior, Animal; Chloride Channels; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Ion Channel Gating; Male; Naltrexone; Pentobarbital; Picrotoxin; Rats; Receptors, GABA; Reinforcement Schedule | 1994 |
Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Propofol; Receptors, GABA-A; Strychnine; Xenopus laevis | 1995 |
GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?
Topics: Acetylcarnitine; Acetylcholine; Action Potentials; Animals; Bicuculline; Chloride Channels; Clonazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Potassium Chloride; Pregnanolone; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Substrate Specificity; Tetrodotoxin; Zinc | 1994 |
The cell surface progesterone receptor which stimulates calcium influx in human sperm is unlike the A ring reduced steroid site on the GABAA receptor/chloride channel.
Topics: Acrosome; Binding Sites; Calcium; Chloride Channels; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Male; Pentobarbital; Picrotoxin; Progesterone; Receptors, GABA; Receptors, Progesterone; Spermatozoa | 1994 |
[Central inhibition action of Valeriana jatamansii Jones].
Topics: Analgesics; Animals; Anticonvulsants; Drug Synergism; Drugs, Chinese Herbal; Female; Hypnotics and Sedatives; Male; Mice; Pentobarbital; Picrotoxin; Seizures; Semicarbazides | 1994 |
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis | 1994 |
Pentobarbitone, but not propofol, produces pre-emptive analgesia in the rat formalin model.
Topics: Analgesics; Anesthesia, Intravenous; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Male; Pain; Pentobarbital; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
Studies on picrotoxin binding sites of GABAA receptors in rat cortical synaptoneurosomes.
Topics: Animals; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorine; Desoxycorticosterone; Diazepam; In Vitro Techniques; Male; Membranes; Muscimol; Pentobarbital; Picrotoxin; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids; Synaptosomes | 1994 |
Dual action of the cyclodiene insecticide dieldrin on the gamma-aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons.
Topics: Animals; Binding Sites; Chlordiazepoxide; Chloride Channels; Dieldrin; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons, Afferent; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1994 |
Structure, pharmacology and function of GABA-A receptors in cochlear outer hair cells.
Topics: Animals; Clorazepate Dipotassium; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Membrane Potentials; Pentobarbital; Picrotoxin; Receptors, GABA-A | 1993 |
Pentobarbital, diazepam, and ethanol abolish the interphase diminution of pain in the formalin test: evidence for pain modulation by GABAA receptors.
Topics: Analgesics; Animals; Chloride Channels; Diazepam; Ethanol; Flumazenil; Formaldehyde; Male; Pain Measurement; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1993 |
Comparison of the effects of propofol, diazepam and pentobarbital on hippocampal potentials evoked by prepyriform stimulation in the freely behaving rat.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Diazepam; Electric Stimulation; Electroencephalography; Evoked Potentials; Female; Hippocampus; Pentobarbital; Picrotoxin; Propofol; Rats; Sleep | 1993 |
Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.
Topics: Action Potentials; Animals; Bicuculline; Culture Techniques; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Pentobarbital; Picrotoxin; Rats; Synapses; Synaptic Transmission; Zinc | 1993 |
Electrophysiological characterization of GABAA receptors in anterior pituitary cells of newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Diazepam; Drug Tolerance; Electric Conductivity; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pituitary Gland, Anterior; Rats; Receptors, GABA; Zinc | 1995 |
L-lysine is a barbiturate-like anticonvulsant and modulator of the benzodiazepine receptor.
Topics: Animals; Anions; Anticonvulsants; Barbiturates; Bicuculline; Brain Chemistry; Cattle; Central Nervous System Depressants; Diazepam; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentobarbital; Picrotoxin; Radioligand Assay; Receptors, GABA-A; Stimulation, Chemical | 1995 |
Behavioral effects of acute and long-term administration of catnip (Nepeta cataria) in mice.
Topics: Animals; Behavior, Animal; Catalepsy; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Plant Extracts; Plant Leaves; Plants, Medicinal; Seizures; Sleep; Stereotyped Behavior; Strychnine | 1995 |
Pentobarbitone induces Fos in astrocytes: increased expression following picrotoxin and seizures.
Topics: Animals; Antibody Specificity; Astrocytes; Chloride Channels; Convulsants; GABA-A Receptor Antagonists; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Male; Oncogene Proteins v-fos; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures | 1996 |
Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms.
Topics: Animals; Carbolines; Cerebellum; Convulsants; Diazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channels; Isomerism; Membrane Potentials; Mice; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Transfection | 1996 |
The agonistic action of pentobarbital on GABAA beta-subunit homomeric receptors.
Topics: Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Mice; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Xenopus | 1996 |
Pentobarbital modulatory effect on GABA binding sites in developing chick optic lobe.
Topics: Animals; Bicuculline; Brain; Chick Embryo; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Pentobarbital; Picrotoxin; Sesterterpenes; Synaptic Membranes | 1995 |
Subcellular localization of gamma-aminobutyric acid type A receptors is determined by receptor beta subunits.
Topics: Animals; DNA, Complementary; Dogs; Electrophysiology; Epitopes; Gene Expression; Kidney; Microinjections; Microscopy, Phase-Contrast; Pentobarbital; Picrotoxin; Protein Conformation; Receptors, GABA-A; Subcellular Fractions | 1996 |
Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons.
Topics: Animals; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Pregnancy; Prohibitins; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
A behavioural and neurochemical study in rats of the pharmacology of loreclezole, a novel allosteric modulator of the GABAA receptor.
Topics: Allosteric Regulation; Animals; Behavior, Animal; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; GABA Modulators; Hypnotics and Sedatives; Male; Muscle Relaxation; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Seizures; Sesterterpenes; Triazoles | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Hyperalgesic effect induced by barbiturates, midazolam and ethanol: pharmacological evidence for GABA-A receptor involvement.
Topics: Animals; Barbiturates; Central Nervous System Depressants; Ethanol; GABA Antagonists; GABA Modulators; Hyperalgesia; Male; Midazolam; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thiopental | 1997 |
Inhibitory effects of corymine, an alkaloidal component from the leaves of Hunteria zeylanica, on glycine receptors expressed in Xenopus oocytes.
Topics: Alkaloids; Animals; Bicuculline; Brain; Convulsants; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Midazolam; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Plant Leaves; Rats; Receptors, GABA-A; Receptors, Glycine; Trees; Xenopus | 1997 |
The interactions of hexachlorocyclohexane isomers with human gamma-aminobutyric acid(A) receptors expressed in Xenopus oocytes.
Topics: Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Humans; Insecticides; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Xenopus | 1997 |
Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation.
Topics: Animals; Ethanol; GABA Modulators; Hexobarbital; Pentobarbital; Picrotoxin; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA Splicing; RNA, Messenger | 1997 |
Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzolamide; Bicarbonates; Carbonic Anhydrases; Enzyme Inhibitors; Ethoxzolamide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Models, Neurological; Pentobarbital; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 1997 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
GABA-evoked depolarisations in the rat cortical wedge: involvement of GABAA receptors and HCO3- ions.
Topics: Animals; Bicarbonates; Bicuculline; Cerebral Cortex; Chlordiazepoxide; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Ions; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
Ethanol selectively enhances the hyperpolarizing component of neocortical neuronal responses to locally applied GABA.
Topics: Animals; Central Nervous System Depressants; Electrophysiology; Ethanol; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neocortex; Neurons; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1998 |
Functional characterization and visualization of a GABAA receptor-GFP chimera expressed in Xenopus oocytes.
Topics: Anesthetics; Animals; Bicuculline; Cell Membrane; Desoxycorticosterone; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Ion Channel Gating; Luminescent Proteins; Membrane Potentials; Microscopy, Confocal; Midazolam; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Fusion Proteins; Xenopus laevis | 1998 |
Suppression of parasympathetic reflex vasodilatation in the lower lip of the cat by isoflurane, propofol, ketamine and pentobarbital: implications for mechanisms underlying the production of anaesthesia.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; GABA Antagonists; Hypnotics and Sedatives; Isoflurane; Ketamine; Lip; Male; Parasympathetic Nervous System; Pentobarbital; Picrotoxin; Propofol; Reflex; Vasodilation | 1998 |
Synaptic activation of GABAA receptors induces neuronal uptake of Ca2+ in adult rat hippocampal slices.
Topics: Animals; Calcium; Carbonic Anhydrase Inhibitors; Electric Stimulation; Ethoxzolamide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; GABA Antagonists; GABA Modulators; Ganglionic Stimulants; Hippocampus; In Vitro Techniques; Neurons; Pentobarbital; Picrotoxin; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, GABA-A; Synapses | 1999 |
GABA(A) receptors mediate inhibition of T cell responses.
Topics: Amidines; Animals; Autocrine Communication; Bicuculline; CD3 Complex; Cell Division; Enzyme Inhibitors; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hypersensitivity, Delayed; Immunosuppression Therapy; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred NOD; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; T-Lymphocytes; Vigabatrin | 1999 |
Synaptic membrane freezing affects modulatory sites in avian central nervous system GABA(A) receptor.
Topics: Animals; Binding Sites; Chickens; Drug Synergism; Freezing; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Pentobarbital; Picrotoxin; Pregnanolone; Receptors, GABA-A; Sesterterpenes; Synaptic Membranes; Tectum Mesencephali; Tritium | 1999 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
Selective cytostatic and neurotoxic effects of avermectins and activation of the GABAalpha receptors.
Topics: Animals; Bicuculline; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Ivermectin; Male; Neuroblastoma; Neurons; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Septal Nuclei; Tumor Cells, Cultured | 1999 |
Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anticonvulsants; Arachidonic Acid; Binding, Competitive; Cells, Cultured; Cyclooxygenase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Fatty Acids; Fatty Acids, Monounsaturated; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Indomethacin; Kidney; Linoleic Acid; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection; Triazoles | 2000 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected].
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Bicuculline; Cells, Cultured; Female; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA-A; Steroids; Xenopus laevis | 2000 |
Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Count; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; GABA Modulators; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Pentobarbital; Picrotoxin; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Stereoisomerism | 2001 |
Functional pharmacology of GABA(A) receptors containing the chicken brain gamma 4 subunit.
Topics: Animals; Bicuculline; Brain Chemistry; Chickens; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis; Zinc | 2001 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors.
Topics: Allosteric Regulation; Animals; Bicuculline; Electric Conductivity; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Xenopus laevis | 2001 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
GABA(B) and NMDA receptors contribute to spindle-like oscillations in rat thalamus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Female; Fourier Analysis; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Magnesium; Male; Membrane Potentials; Organ Culture Techniques; Organophosphorus Compounds; Pentobarbital; Periodicity; Picrotoxin; Quinoxalines; Rats; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Species Specificity; Thalamus | 2001 |
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Injections, Intraventricular; Male; Mice; Pentobarbital; Picrotoxin; Pyrazines; Seizures; Sleep; Time Factors; Valproic Acid | 2001 |
Small-dose pentobarbital enhances synaptic transmission in rat hippocampus.
Topics: Acetazolamide; Animals; Bicarbonates; Carbonic Anhydrase Inhibitors; Electric Stimulation; Evoked Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Sedative and anticonvulsant activities of goodyerin, a flavonol glycoside from Goodyera schlechtendaliana.
Topics: Animals; Anticonvulsants; Convulsants; Disaccharides; Flavonoids; Flavonols; Glycosides; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Orchidaceae; Pentobarbital; Phytotherapy; Picrotoxin; Plant Extracts; Rats; Rats, Sprague-Dawley; Seizures; Sleep Wake Disorders | 2002 |
Overexpression of the GABA(A) receptor epsilon subunit results in insensitivity to anaesthetics.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Blotting, Western; Cell Line; Cloning, Molecular; DNA, Complementary; Etomidate; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Pentobarbital; Picrotoxin; Protein Engineering; Receptors, GABA-A; Steroids; Transfection; Xenopus laevis | 2002 |
Relative picrotoxin insensitivity distinguishes ionotropic GABA receptor-mediated IPSCs in hippocampal interneurons.
Topics: Animals; Bicuculline; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Iontophoresis; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyramidal Cells; Pyridines; Receptors, GABA; Receptors, GABA-A; Zolpidem | 2002 |
Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.).
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sea Bream | 2002 |
Convulsant and anticonvulsant effects on spontaneous CA3 population bursts.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Convulsants; Epilepsy; Hippocampus; Models, Neurological; Organ Culture Techniques; Pentobarbital; Picrotoxin; Pyramidal Cells; Rats; Rats, Wistar | 2003 |
Analysis of the antagonism between some brain stem stimulants and pentobarbital.
Topics: Bemegride; Brain Stem; Central Nervous System Agents; Central Nervous System Stimulants; Flavones; Pentobarbital; Pentylenetetrazole; Picrotoxin; Pyrans | 1963 |
Dimefline (Rec 7-0267), other C.N.S. stimulants and lobeline as antagonists of pentobarbital.
Topics: Amphetamine; Barbiturates; Bemegride; Benzoates; Central Nervous System Stimulants; Flavones; Flavonoids; Lobeline; Pentobarbital; Pentylenetetrazole; Picrotoxin | 1962 |
PHARMACOLOGICAL STUDIES ON PRESYNAPTIC INHIBITION.
Topics: Aminobutyrates; Barbiturates; Bemegride; Cats; Chloralose; Diphosphates; Gallamine Triethiodide; Nicotine; Pentobarbital; Pentylenetetrazole; Pharmacology; Physiology; Physostigmine; Picrotoxin; Research; Spinal Cord; Spinal Nerves; Strychnine; Sulfonic Acids; Synapses | 1963 |
THE HISTOMORPHOLOGY OF EXPERIMENTAL EXCITATION.
Topics: Acridines; Coloring Agents; Depression; Depressive Disorder; Hippocampus; Histology; Lysergic Acid Diethylamide; Neuroglia; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Research; Seizures; Staining and Labeling; Toxicology | 1964 |
THE PHARMACOLOGY OF PRESYNAPTIC INHIBITION.
Topics: Amino Acids; Anesthetics; Electrophysiology; Ether; Glutamates; Neurophysiology; Parasympathomimetics; Pentobarbital; Pharmacology; Picrotoxin; Reflex; Research; Spinal Cord; Strychnine; Toxicology | 1964 |
EXPERIMENTAL AND CLINICAL BARBITURATE ANTAGONISM.
Topics: Barbiturates; Bemegride; Mice; Pentobarbital; Pentylenetetrazole; Pharmacology; Picrotoxin; Pregnanediones; Research; Toxicology | 1964 |
An operant determination of the behavioral mechanism of benzodiazepine enhancement of food intake.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Conditioning, Operant; Eating; Male; Motivation; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Reinforcement Schedule; Taste | 2006 |
In vivo characterization of sedative activities of Fossilia Mastodi OSSIS.
Topics: Animals; Diazepam; Fossils; Hypnotics and Sedatives; Male; Mammals; Mice; Mice, Inbred ICR; Motor Activity; Pentobarbital; Picrotoxin; Seizures; Sleep; Tissue Extracts | 2006 |
Evidence that the beta-acids fraction of hops reduces central GABAergic neurotransmission.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Carbon Dioxide; Central Nervous System; Cerebellum; Depression, Chemical; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Humulus; Male; Maze Learning; Motor Activity; Pentobarbital; Picrotoxin; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sleep; Solvents; Swimming; Synaptic Transmission | 2007 |
Pharmacologically induced and stimulus evoked rhythmic neuronal oscillatory activity in the primary motor cortex in vitro.
Topics: Animals; Beta Rhythm; Carbachol; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Agonists; Extracellular Space; Fourier Analysis; GABA Agonists; GABA Antagonists; GABA Modulators; In Vitro Techniques; Kainic Acid; Male; Motor Cortex; Muscarinic Agonists; Neurons; Pentobarbital; Picrotoxin; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Zolpidem | 2008 |
Preoptic hypnogenic area and reticular activating system.
Topics: Action Potentials; Animals; Cats; Decerebrate State; Dextroamphetamine; Electric Stimulation; Electroencephalography; Pentobarbital; Picrotoxin; Preoptic Area; Reticular Formation; Sleep; Strychnine; Thalamic Nuclei | 1973 |
Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Fluorometry; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Conformation; Rats; Receptors, GABA-A; Rhodamines; Xenopus laevis | 2009 |
Topiramate modulation of β(1)- and β(3)-homomeric GABA(A) receptors.
Topics: Animals; Drug Interactions; Electrophysiological Phenomena; Fructose; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Inhibitory Concentration 50; Membrane Potentials; Oocytes; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Topiramate; Transfection; Triazoles; Xenopus laevis | 2011 |
Gamma oscillations are generated locally in an attention-related midbrain network.
Topics: Animals; Animals, Newborn; Atropine; Attention; Biophysics; Brain Mapping; Chickens; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA Modulators; In Vitro Techniques; Mesencephalon; Muscarinic Antagonists; Pentobarbital; Periodicity; Photic Stimulation; Picrotoxin; Receptors, Cholinergic; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synaptic Potentials; Valine | 2012 |
In vivo recordings of GnRH neuron firing reveal heterogeneity and dependence upon GABAA receptor signaling.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrodes, Implanted; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; Female; GABA Agonists; GABA Antagonists; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Muscimol; Neurons; Patch-Clamp Techniques; Pentobarbital; Pharynx; Picrotoxin; Receptors, GABA-A; Signal Transduction; Tetrodotoxin | 2013 |
Synthesis, anticonvulsant, sedative and anxiolytic activities of novel annulated pyrrolo[1,4]benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepinones; Exploratory Behavior; Heterocyclic Compounds, 4 or More Rings; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Molecular Structure; Pentobarbital; Picrotoxin; Reflex, Abnormal; Seizures; Strychnine | 2014 |
A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
Topics: Animals; Bacterial Proteins; Cell Membrane; Chlorides; Etomidate; Extracellular Space; gamma-Aminobutyric Acid; Humans; Ligand-Gated Ion Channels; Membrane Potentials; Mutation; Neurotransmitter Agents; Oocytes; Pentobarbital; Picrotoxin; Propofol; Protein Domains; Protons; Receptors, GABA-B; Recombinant Fusion Proteins; Xenopus laevis | 2017 |
Probing GABA
Topics: Animals; Binding Sites; Cell Line; Humans; Membrane Potentials; Mice; Neurotransmitter Agents; Pentobarbital; Picrotoxin; Pregnenolone; Protein Domains; Receptors, GABA-A; Recombinant Proteins | 2018 |