picrotoxin has been researched along with kainic acid in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (24.32) | 18.7374 |
| 1990's | 28 (37.84) | 18.2507 |
| 2000's | 18 (24.32) | 29.6817 |
| 2010's | 9 (12.16) | 24.3611 |
| 2020's | 1 (1.35) | 2.80 |
| Authors | Studies |
|---|---|
| Di Chiara, G; Gessa, GL; Morelli, M; Mulas, ML; Porceddu, ML | 1 |
| Baraban, JM; Blatter, LA; Murphy, TH; Wier, WG | 1 |
| Zhang, DS; Zhang, L; Zhang, SS | 1 |
| Artigas, F; de Vera, N; Martínez, E | 1 |
| Uretsky, NJ; Wallace, LJ | 1 |
| Lok, SY; Meldrum, BS; Millan, MH; Obrenovitch, TP; Sarna, GS; Symon, L | 1 |
| Rizzi, M; Samanin, R; Serafini, R; Stasi, MA; Vezzani, A; Viganò, G | 1 |
| Gatti, PJ; Gillis, RA | 1 |
| De Barry, J; Mathis, C; Ungerer, A | 1 |
| Jackson, H; Parks, TN | 1 |
| Godlevskiĭ, LS; Kryzhanovskiĭ, GN; Mazarati, AM; Shandra, AA | 1 |
| Kulkarni, SK; Mehta, AK; Ticku, MK | 1 |
| Bossut, D; Frenk, H; Mayer, DJ; Urca, G | 1 |
| Bossut, D; Frenk, H; Mayer, DJ | 1 |
| Albertson, TE; Joy, RM | 1 |
| Curran, T; Hempstead, J; Macgregor-Leon, PF; Mitchelmore, C; Morgan, JI; Sonnenberg, JL | 1 |
| Connor, JD; Henry, RT | 1 |
| Cohen, A; Erez, U; Frenk, H; Goldberg, O; Teichberg, VI | 1 |
| Goldberg, O; Teichberg, VI | 1 |
| Shreve, PE; Uretsky, NJ | 1 |
| Herrera-Marschitz, M; Ståhle, L; Tossman, U; Ungerstedt, U; Zetterström, T | 1 |
| Packan, DR; Sapolsky, RM; Vale, WW | 1 |
| Kato, S; Negishi, K; Teranishi, T | 1 |
| Canonico, PL; Di Chiara, G; Imperato, A; Nicoletti, F; Piacente, B; Raffaele, R; Scapagnini, U | 1 |
| Di Chiara, G; Diana, M; Imperato, A; Nicoletti, F; Scapagnini, U | 1 |
| Ishida, M; Shinozaki, H | 1 |
| Javid, MJ; Stone, WE | 1 |
| Agnoli, A; Forchetti, C; Pacitti, C; Scarnati, E | 1 |
| Dowling, JE; Grant, GB | 1 |
| Larsson, HP; Lecar, H; Picaud, S; Wellis, DP; Werblin, F | 1 |
| Dunham, L; Guillet, R | 1 |
| Boksa, P; Chaudieu, I; Quirion, R; St-Pierre, JA | 1 |
| Dong, CJ; Picaud, SA; Werblin, FS | 1 |
| Cano, J; Santiago, M; Westerink, BH | 1 |
| Benedikz, E; Bergold, PJ; Casaccia-Bonnefil, P; Rai, R | 1 |
| Ossowska, K | 1 |
| Carroll, DM; Grossman, AB; Kirkby, RD; Subramaniam, S | 1 |
| Camón, L; de Vera, N; Giménez-Llort, L; Martínez, E | 1 |
| Brusentsov, AI; Godlevskiĭ, LS; Mikhaleva, II; Nickel, B; Petrashevich, VP; Shandra, AA; Vast'ianov, RS | 1 |
| Foti, D; Imperato, A; Marano, P; Nicoletti, F; Patti, F; Rampello, L; Reggio, A; Speciale, C | 1 |
| Balestra, M; Borrelli, AR; Cramer, CL; Eismann, MS; Freedman, LR; Hudzik, TJ; Knowles, MK; Mahmood, N; McCarthy, DJ; Murray, RJ; Palmer, GC; Stagnitto, ML | 1 |
| Cattaert, D; Le Ray, D | 1 |
| Agassandian, C; Ben Ari, Y; Guillot, S; Khrestchatisky, M; Rivera, S | 1 |
| Ikegaya, Y | 1 |
| Mackenzie, L; Willoughby, JO | 1 |
| Chen, Q; Hardy, K; Moulder, K; Olney, JW; Romano, C; Tenkova, T | 1 |
| Boehrer, A; Marescaux, C; Reibel, S; Simler, S; Vergnes, M | 1 |
| Isaac, JT; Kidd, FL | 2 |
| Connaughton, VP; Nelson, R | 1 |
| Fendt, M | 1 |
| Higgs, MH; Lukasiewicz, PD; Olney, JW; Romano, C; Salvay, D; Shen, DW | 1 |
| Dubé, C; Koning, E; Nehlig, A | 1 |
| Habaguchi, T; Ohtinata-Sugimoto, J; Saitoh, K; Sakamoto, T; Takakusaki, K | 1 |
| Chappell, RL; Rosenstein, FJ | 1 |
| Fei, J; Guo, LH; Ma, YH; Mei, ZT; Zhao, WJ | 1 |
| De Mello, FG; Ferreira, ST; Louzada, PR; Mendonca-Silva, DL; Noël, F; Paula Lima, AC | 1 |
| Aunis, D; Depaulis, A; Gobaille, S; Lê-Pham, BT; Maitre, M; Nail-Boucherie, K | 1 |
| Broberg, M; Nilsson, M; Pope, KJ; Wallace, A; Willoughby, JO; Wilson, J | 1 |
| Hall, SD; Stanford, IM; Woodhall, GL; Yamawaki, N | 1 |
| Albert, GW; Howard, MA; Schnizler, MK; Severson, MA; Welsh, MJ; Wemmie, JA; Ziemann, AE | 1 |
| Jain, R; Kaur, N; Krishnamoorthy, S; Meena, CL; Monga, V; Pawar, C; Rajput, SK; Sharma, SS | 1 |
| Di Cosmo, A; Di Cristo, C; Moccia, F; Winlow, W | 1 |
| Ingole, S; Jain, G; Jain, R; Kaur, N; Meena, CL; Monga, V; Rajput, SK; Sharma, SS; Singh, JN | 1 |
| Bulley, S; Shen, W | 1 |
| Bielefeld, L; Froriep, UP; Haas, CA; Häussler, U; Wolfart, J | 1 |
| Benes, FM; Bolshakov, VY; Gisabella, B | 1 |
| Dhir, A; Rogawski, MA; Zolkowska, D | 1 |
| Hou, XJ; Li, XM; Ni, KM; Yang, JM | 1 |
| Andersson, M; Berglind, F; Bielefeld, P; Deisseroth, K; Kirik, D; Kokaia, M; Ledri, M; Melis, M; Nikitidou, L; Sørensen, AT | 1 |
| Alessi, C; Magistretti, J; Raspanti, A | 1 |
| Bai, R; Basser, PJ; Plenz, D; Stewart, CV | 1 |
| Bai, R; Basser, PJ; Plenz, D; Springer, CS | 1 |
| Adeyemi, OO; Afolayan, O; Ajayi, AM; Ben-Azu, B; Ishola, IO; James, AB; Nwose, E; Olubodun-Obadun, TG; Umukoro, S | 1 |
1 review(s) available for picrotoxin and kainic acid
| Article | Year |
|---|---|
Effect of GABAergic and glutamatergic drugs injected into the ventral pallidum on locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Ibotenic Acid; Kainic Acid; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin | 1991 |
73 other study(ies) available for picrotoxin and kainic acid
| Article | Year |
|---|---|
Substantia nigra as an out-put station for striatal dopaminergic responses: role of a GABA-mediated inhibition of pars reticulata neurons.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Hydroxydopamines; Kainic Acid; Male; Neurons; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra | 1979 |
Spontaneous synchronous synaptic calcium transients in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Electrophysiology; Fetus; Fluorescent Dyes; Kainic Acid; Kinetics; Membrane Potentials; Microscopy, Fluorescence; Neurons; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin; Time Factors | 1992 |
[Influence of GABAergic neurons in the brain on central effects of kainate on the cardiovascular system].
Topics: Aminooxyacetic Acid; Animals; Blood Pressure; Brain; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intraventricular; Kainic Acid; Male; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Semicarbazides | 1991 |
Differential response of rat brain polyamines to convulsant agents.
Topics: Animals; Biogenic Polyamines; Body Weight; Brain; Convulsants; Hexachlorocyclohexane; Kainic Acid; Male; Ornithine Decarboxylase; Pentylenetetrazole; Picrotoxin; Putrescine; Rats; Rats, Inbred Strains; Sesterterpenes; Spermidine; Spermine | 1991 |
Changes in rat brain extracellular glutamate concentration during seizures induced by systemic picrotoxin or focal bicuculline injection: an in vivo dialysis study with on-line enzymatic detection.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicuculline; Brain Chemistry; Cerebral Cortex; Dialysis; Electroencephalography; Electroshock; Extracellular Space; Glutamates; Hippocampus; Injections; Kainic Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1991 |
A peptidase-resistant cyclic octapeptide analogue of somatostatin (SMS 201-995) modulates seizures induced by quinolinic and kainic acids differently in the rat hippocampus.
Topics: Animals; Atropine; Convulsants; Electroencephalography; Hippocampus; Kainic Acid; Male; Octreotide; Picrotoxin; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures | 1991 |
Interaction between pressor and depressor areas in cat ventrolateral medulla.
Topics: Animals; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Kainic Acid; Male; Medulla Oblongata; Models, Neurological; Organ Specificity; Picrotoxin; Strychnine; Time Factors | 1991 |
NMDA antagonist properties of gamma-L-glutamyl-L-aspartate demonstrated on chemically induced seizures in mice.
Topics: Animals; Anticonvulsants; Behavior, Animal; Dipeptides; Dose-Response Relationship, Drug; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Seizures | 1990 |
Anticonvulsant action of an arylamine-containing fraction from Agelenopsis spider venom.
Topics: Animals; Anticonvulsants; Bicuculline; Biogenic Amines; Chemical Fractionation; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Intraventricular; Kainic Acid; Male; Molecular Weight; Picrotoxin; Rats; Rats, Inbred Strains; Spider Venoms | 1990 |
[Effects of destruction and activation of limbic structures on formation of convulsive and emotional disorders during picrotoxin kindling].
Topics: Amygdala; Animals; Behavior, Animal; Emotions; Epilepsy; Hippocampus; Kainic Acid; Kindling, Neurologic; Male; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Comparison of anticonvulsant effect of ethanol against NMDA-, kainic acid- and picrotoxin-induced convulsions in rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Ethanol; Kainic Acid; Male; N-Methylaspartate; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1990 |
Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds.
Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P | 1988 |
Is substance P a primary afferent neurotransmitter for nociceptive input? II. Spinalization does not reduce and intrathecal morphine potentiates behavioral responses to substance P.
Topics: Animals; Decerebrate State; Drug Interactions; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P | 1988 |
Convulsant-induced changes in perforant path-dentate gyrus excitability in urethane anesthetized rats.
Topics: Animals; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Hippocampus; Kainic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain.
Topics: Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Blotting, Northern; Convulsants; DNA-Binding Proteins; Electroshock; Gene Expression Regulation; Immunoblotting; Kainic Acid; Male; Mice; Mice, Inbred BALB C; N-Methylaspartate; Nucleic Acid Hybridization; Pentylenetetrazole; Picrotoxin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Seizures; Transcription Factors | 1989 |
Axons of passage may be responsible for fastigial nucleus pressor response.
Topics: Animals; Axons; Blood Pressure; Cerebellar Nuclei; Electric Stimulation; Heart Rate; Kainic Acid; Male; Muscimol; Picrotoxin; Posture; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Anticonvulsant properties of 3-hydroxy-2-quinoxalinecarboxylic acid, a newly found antagonist of excitatory amino acids.
Topics: Animals; Anticonvulsants; Aspartic Acid; Electroencephalography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Structure-Activity Relationship | 1985 |
A dipeptide derived from kainic and L-glutamic acids: a selective antagonist of amino acid induced neuroexcitation with anticonvulsant properties.
Topics: Animals; Aspartic Acid; Cell Membrane Permeability; Corpus Striatum; Dipeptides; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Picrotoxin; Quisqualic Acid; Rats; Seizures; Sodium | 1985 |
Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Aspartic Acid; Basal Ganglia; Brain; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata; Synaptic Transmission | 1988 |
Functional classification of different dopamine receptors.
Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain; Dominance, Cerebral; Dopamine; Ergolines; Flupenthixol; gamma-Aminobutyric Acid; Hydroxydopamines; Kainic Acid; Oxidopamine; Pergolide; Picrotoxin; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Synapses | 1985 |
Glucocorticoid toxicity in the hippocampus: in vitro demonstration.
Topics: Animals; Cells, Cultured; Corticosterone; Drug Interactions; Glucose; Hippocampus; Kainic Acid; L-Lactate Dehydrogenase; Paraquat; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains | 1988 |
Dopamine inhibits calcium-independent gamma-[3H]aminobutyric acid release induced by kainate and high K+ in the fish retina.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Dopamine; Fishes; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; N-Methylaspartate; Oxadiazoles; Picrotoxin; Potassium; Pyrrolidines; Quisqualic Acid; Retina; Serotonin | 1985 |
Motor and postural effects of kainic acid or GABA agonist and antagonist injection into the cerebellar nucleus fastigii.
Topics: Animals; Cerebellar Nuclei; Kainic Acid; Motor Skills; Muscimol; Muscle Contraction; Oxazoles; Picrotoxin; Posture; Pyrrolidines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1983 |
Fastigial influences on postural tonus as studied by kainate lesions and by local infusion of GABAergic drugs in the rat.
Topics: Animals; Bicuculline; Cerebellar Nuclei; Diazepam; Functional Laterality; gamma-Aminobutyric Acid; Kainic Acid; Male; Motor Activity; Muscle Tonus; Picrotoxin; Posture; Pyrrolidines; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1984 |
Electrophysiological studies of kainate, quisqualate, and ibotenate action on the crayfish neuromuscular junction.
Topics: Alanine; Animals; Astacoidea; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Neuromuscular Junction; Oxadiazoles; Oxazoles; Picrotoxin; Pyrrolidines; Quisqualic Acid | 1981 |
Effects of anticonvulsants and glutamate antagonists on the convulsive action of kainic acid.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bemegride; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; Pentylenetetrazole; Picrotoxin; Pyrrolidines; Seizures | 1980 |
Striatal cholinergic receptors and dyskinetic motor activity in the rat.
Topics: Animals; Corpus Striatum; Dopamine; Hydroxydopamines; Kainic Acid; Male; Movement Disorders; Neural Pathways; Picrotoxin; Rats; Receptors, Cholinergic; Substantia Nigra; Tubocurarine | 1980 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Cone photoreceptors respond to their own glutamate release in the tiger salamander.
Topics: Ambystoma; Animals; Aspartic Acid; Calcium; Chloride Channels; Exocytosis; Fluorescent Dyes; Fura-2; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Retinal Cone Photoreceptor Cells; Synapses; Synaptic Transmission; Time Factors | 1995 |
Neonatal caffeine exposure and seizure susceptibility in adult rats.
Topics: Animals; Animals, Newborn; Bicuculline; Brain; Caffeine; Female; Kainic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Receptors, Purinergic P1; Seizures; Sex Factors; Strychnine | 1995 |
GABAA receptor-mediated inhibition of N-methyl-D-aspartate-evoked [3H]dopamine release from mesencephalic cell cultures.
Topics: Animals; Baclofen; Cells, Cultured; Dopamine; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mesencephalon; Muscimol; N-Methylaspartate; Picrotoxin; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA; Ventral Tegmental Area | 1994 |
GABA transporters and GABAC-like receptors on catfish cone- but not rod-driven horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Chloride Channels; Crotonates; Electrophysiology; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ictaluridae; Kainic Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Muscimol; Organic Anion Transporters; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Stereoisomerism; Time Factors | 1994 |
Are bilateral nigrostriatal dopaminergic pathways functionally linked in the rat brain? A microdialysis study in conscious rats.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Corpus Striatum; Dopamine; Kainic Acid; Male; Microdialysis; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Wistar; Substantia Nigra; Synaptic Transmission; Tetrodotoxin | 1993 |
Excitatory and inhibitory pathways modulate kainate excitotoxicity in hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Fibers; Neural Pathways; Neurons; Organ Culture Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Synapses | 1993 |
Interaction between striatal excitatory amino acid and gamma-aminobutyric acid (GABA) receptors in the turning behaviour of rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Caudate Nucleus; Data Interpretation, Statistical; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Kainic Acid; Male; N-Methylaspartate; Neostriatum; Picrotoxin; Putamen; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate | 1995 |
Factors determining proconvulsant and anticonvulsant effects of inhibitors of nitric oxide synthase in rodents.
Topics: Animals; Anticonvulsants; Behavior, Animal; Convulsants; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Indazoles; Kainic Acid; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Picrotoxin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Species Specificity | 1996 |
Concentration of putrescine in plasma, frontal cortex and hippocampus of rats after systemic administration of the convulsants N-methyl-D-aspartate, pentylentetrazol, picrotoxinine, lindane and 4-aminopyridine.
Topics: Aminopyrine; Analysis of Variance; Animals; Convulsants; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Excitatory Amino Acid Agonists; Frontal Lobe; Hexachlorocyclohexane; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Putrescine; Rats; Rats, Wistar; Sesterterpenes | 1996 |
[The delta sleep-inducing peptide, its analogs and the serotoninergic system in the development of anticonvulsant action].
Topics: Animals; Anticonvulsants; Convulsants; Delta Sleep-Inducing Peptide; Drug Evaluation, Preclinical; Epilepsy, Generalized; Hippocampus; Kainic Acid; Male; Picrotoxin; Rats; Rats, Wistar; Receptors, Serotonin; Substantia Nigra; Tritium; Tryptophan | 1997 |
[Motor and postural effects in intracerebellar injection of kainic acid: possible role of the bulbar reticular formation].
Topics: Animals; Cerebellar Nuclei; Cerebellum; Drug Interactions; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; Hindlimb; Injections; Kainic Acid; Locomotion; Motor Activity; Muscimol; Muscle Contraction; Picrotoxin; Posture; Purkinje Cells; Reticular Formation; Syndrome | 1983 |
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Strychnine; Time Factors; Weaning | 1999 |
Direct glutamate-mediated presynaptic inhibition of sensory afferents by the postsynaptic motor neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astacoidea; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feedback; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Male; Membrane Potentials; Motor Neurons; Neural Inhibition; Neurons, Afferent; Picrotoxin; Presynaptic Terminals; Quinoxalines; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1998 |
Serum deprivation-induced apoptosis in cultured hippocampi is prevented by kainate.
Topics: Analysis of Variance; Animals; Apoptosis; Culture Media, Serum-Free; Cycloheximide; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Kainic Acid; Membrane Potentials; Organ Culture Techniques; Picrotoxin; Protein Synthesis Inhibitors; Quinoxalines; Rats; Rats, Wistar | 1998 |
Abnormal targeting of developing hippocampal mossy fibers after epileptiform activities via L-type Ca2+ channel activation in vitro.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Kainic Acid; Microscopy, Confocal; Mossy Fibers, Hippocampal; Picrotoxin; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin | 1999 |
Picrotoxin-, kainic acid- and seizure-induced Fos in brainstem, with special reference to catecholamine cell groups.
Topics: Animals; Brain Stem; Gene Expression Regulation; Genes, fos; Kainic Acid; Male; Neurons; Neurotoxins; Organ Specificity; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Seizures; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1999 |
Excitotoxic cell death dependent on inhibitory receptor activation.
Topics: Action Potentials; Animals; Bicuculline; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebellar Cortex; Chick Embryo; Chloride Channels; Chlorides; Excitatory Amino Acid Agonists; GABA Antagonists; Glycine; Ion Channel Gating; Ion Transport; Kainic Acid; Neuroprotective Agents; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glycine; Retina; Strychnine | 1999 |
Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbolines; Convulsants; Electroencephalography; Epilepsy, Absence; Frontal Lobe; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoniazid; Kainic Acid; Limbic System; Male; Parietal Lobe; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Strychnine | 2000 |
Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Biological Transport; Dicarboxylic Acids; Diuretics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurotransmitter Uptake Inhibitors; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Somatosensory Cortex; Synaptic Transmission; Thalamus | 2000 |
Axonal stratification patterns and glutamate-gated conductance mechanisms in zebrafish retinal bipolar cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Chlorides; Cycloleucine; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Neurons; Picrotoxin; Retina; Strychnine; Zebrafish | 2000 |
Expression and conditioned inhibition of fear-potentiated startle after stimulation and blockade of AMPA/Kainate and GABA(A) receptors in the dorsal periaqueductal gray.
Topics: Acoustic Stimulation; Animals; Conditioning, Classical; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fear; Kainic Acid; Light; Male; Microinjections; Periaqueductal Gray; Picrotoxin; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Reflex, Startle | 2000 |
Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Central Nervous System Stimulants; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Kinetics; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, Kainic Acid; Synapses; Synaptic Transmission; Temperature; Thalamus | 2001 |
Morphological and electrophysiological evidence for an ionotropic GABA receptor of novel pharmacology.
Topics: Amacrine Cells; Animals; Bicuculline; Chick Embryo; Chickens; Excitatory Amino Acid Agonists; GABA Antagonists; In Vitro Techniques; Ion Transport; Kainic Acid; Lithium; Neurons; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA; Retina; Retinal Ganglion Cells | 2002 |
Status epilepticus induced by lithium-pilocarpine in the immature rat does not change the long-term susceptibility to seizures.
Topics: Aging; Animals; Animals, Newborn; Cerebellar Cortex; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Kainic Acid; Lithium; Male; Muscarinic Agonists; Pentylenetetrazole; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Status Epilepticus | 2002 |
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-Acetyltransferase; Disease Models, Animal; Efferent Pathways; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Locomotion; Muscarinic Antagonists; Muscimol; Muscle Tonus; N-Methylaspartate; Neural Inhibition; Picrotoxin; Stimulation, Chemical | 2003 |
Endogenous zinc as a retinal neuromodulator: evidence from the skate (Raja erinacea).
Topics: Aminobutyrates; Animals; Cells, Cultured; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Electroretinography; Excitatory Amino Acid Agonists; GABA Antagonists; Histidine; Kainic Acid; Membrane Potentials; Neuroprotective Agents; Patch-Clamp Techniques; Picrotoxin; Retina; Skates, Fish; Zinc | 2003 |
Increase in drug-induced seizure susceptibility of transgenic mice overexpressing GABA transporter-1.
Topics: Animals; Animals, Genetically Modified; Anticonvulsants; Carrier Proteins; Disease Models, Animal; Female; GABA Plasma Membrane Transport Proteins; Genetic Predisposition to Disease; Kainic Acid; Male; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nipecotic Acids; Pentylenetetrazole; Picrotoxin; Seizures | 2003 |
Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Cellular Senescence; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Eye Proteins; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Picrotoxin; Receptors, AMPA; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Taurine | 2004 |
Evidence for a role of the parafascicular nucleus of the thalamus in the control of epileptic seizures by the superior colliculus.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Excitatory Amino Acid Agonists; Extracellular Fluid; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Intralaminar Thalamic Nuclei; Kainic Acid; Male; Microdialysis; Microinjections; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Substantia Nigra; Superior Colliculi | 2005 |
Preseizure increased gamma electroencephalographic activity has no effect on extracellular potassium or calcium.
Topics: Analysis of Variance; Animals; Brain; Calcium; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Extracellular Fluid; Kainic Acid; Male; Picrotoxin; Potassium; Rats; Rats, Sprague-Dawley; Spectrum Analysis | 2007 |
Pharmacologically induced and stimulus evoked rhythmic neuronal oscillatory activity in the primary motor cortex in vitro.
Topics: Animals; Beta Rhythm; Carbachol; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Agonists; Extracellular Space; Fourier Analysis; GABA Agonists; GABA Antagonists; GABA Modulators; In Vitro Techniques; Kainic Acid; Male; Motor Cortex; Muscarinic Agonists; Neurons; Pentobarbital; Picrotoxin; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Zolpidem | 2008 |
Seizure termination by acidosis depends on ASIC1a.
Topics: Acid Sensing Ion Channels; Acidosis; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Carbon Dioxide; Electroencephalography; Female; Hippocampus; Hydrogen-Ion Concentration; Interneurons; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Knockout; Nerve Tissue Proteins; Patch-Clamp Techniques; Pentylenetetrazole; Picrotoxin; Seizures; Sodium Channels; Time Factors | 2008 |
Antiepileptic potential and behavioral profile of L-pGlu-(2-propyl)-L-His-L-ProNH2, a newer thyrotropin-releasing hormone analog.
Topics: Animals; Anticonvulsants; Behavior, Animal; Blood Pressure; Cardiovascular System; Central Nervous System Stimulants; Cerebrovascular Circulation; Convulsants; Electroshock; Hypnotics and Sedatives; Kainic Acid; Male; Mice; Motor Activity; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Seizures; Sleep; Theophylline; Thyrotropin; Thyrotropin-Releasing Hormone | 2009 |
GABA(A)- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Brain; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Lymnaea; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Picrotoxin; Receptors, AMPA; Receptors, GABA-A; Respiration | 2009 |
Neuropharmacological profile of L-pGlu-(1-benzyl)-L-His-L-ProNH2, a newer thyrotropin-releasing hormone analog: effects on seizure models, sodium current, cerebral blood flow and behavioral parameters.
Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Blood Pressure; Brain; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Electrophysiology; Electroshock; Ganglia, Spinal; Kainic Acid; Male; Mice; Motor Activity; Neurons; Pentylenetetrazole; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Statistics, Nonparametric; Thyrotropin-Releasing Hormone | 2009 |
Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Ambystoma; Animals; Calcium; Calcium Channels; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Glycine Agents; Kainic Acid; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Neurotransmitter Agents; Patch-Clamp Techniques; Picrotoxin; Receptors, Glutamate; Retinal Ganglion Cells; Signal Transduction; Strychnine; Synaptic Transmission; Taurine | 2010 |
Septotemporal position in the hippocampal formation determines epileptic and neurogenic activity in temporal lobe epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Convulsants; Disease Models, Animal; Doublecortin Domain Proteins; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; Hippocampus; Kainic Acid; Luminescent Proteins; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Patch-Clamp Techniques; Picrotoxin | 2012 |
Kainate receptor-mediated modulation of hippocampal fast spiking interneurons in a rat model of schizophrenia.
Topics: Amygdala; Animals; Bipolar Disorder; Brain Mapping; CA2 Region, Hippocampal; Disease Models, Animal; Electrophysiology; Hippocampus; Interneurons; Kainic Acid; Male; Oscillometry; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Schizophrenia; Signal Transduction | 2012 |
Seizure protection by intrapulmonary delivery of midazolam in mice.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Administration Routes; Kainic Acid; Male; Mice; Midazolam; Pentylenetetrazole; Picrotoxin; Seizures | 2013 |
Neuregulin 1/ErbB4 enhances synchronized oscillations of prefrontal cortex neurons via inhibitory synapses.
Topics: Action Potentials; Animals; ErbB Receptors; Excitatory Amino Acid Agonists; GABA Antagonists; Gap Junctions; In Vitro Techniques; Interneurons; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neuregulin-1; Neurons; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Receptor, ErbB-4; Synapses | 2014 |
Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.
Topics: Action Potentials; Aminopyridines; Analysis of Variance; Animals; Bacterial Proteins; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; GABA Agents; GABA Antagonists; Halorhodopsins; In Vitro Techniques; Kainic Acid; Luminescent Proteins; Membrane Potentials; Mice; Neurons; Optogenetics; Patch-Clamp Techniques; Picrotoxin; Status Epilepticus; Transduction, Genetic | 2014 |
Two distinct types of depolarizing afterpotentials are differentially expressed in stellate and pyramidal-like neurons of entorhinal-cortex layer II.
Topics: Action Potentials; Animals; Animals, Newborn; Benzimidazoles; Biophysical Phenomena; Central Nervous System Stimulants; Cyclopropanes; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Agonists; Female; In Vitro Techniques; Kainic Acid; Male; Models, Biological; Naphthalenes; Nerve Net; Picrotoxin; Pyramidal Cells; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin | 2016 |
Assessing the sensitivity of diffusion MRI to detect neuronal activity directly.
Topics: Action Potentials; Animals; Body Water; Calcium; Diffusion; Diffusion Magnetic Resonance Imaging; In Vitro Techniques; Interrupted Time Series Analysis; Kainic Acid; Microscopy, Fluorescence; Multimodal Imaging; Neuroimaging; Neurons; Organ Culture Techniques; Osmolar Concentration; Osmotic Pressure; Picrotoxin; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Somatosensory Cortex; Tetrodotoxin | 2016 |
Brain active transmembrane water cycling measured by MR is associated with neuronal activity.
Topics: Animals; Brain; Brain Mapping; Calcium; Cells, Cultured; Contrast Media; Gadolinium; Heterocyclic Compounds; Humans; Kainic Acid; Kinetics; Magnetic Resonance Imaging; Neurons; Organometallic Compounds; Picrotoxin; Rats; Rats, Sprague-Dawley; Signal Processing, Computer-Assisted; Sodium-Potassium-Exchanging ATPase; Somatosensory Cortex; Water | 2019 |
Probable mechanisms involved in the antiepileptic activity of Clerodendrum polycephalum Baker (Labiatae) leaf extract in mice exposed to chemical-induced seizures.
Topics: Animals; Anticonvulsants; Antioxidants; Arginine; Clerodendrum; Cyclooxygenase 2; Flumazenil; Guanosine Monophosphate; Kainic Acid; Lamiaceae; Methylene Blue; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Picrotoxin; Plant Extracts; Receptors, GABA-A; Seizures; Soluble Guanylyl Cyclase; Spasm | 2022 |