Page last updated: 2024-08-23

picrotoxin and isoniazid

picrotoxin has been researched along with isoniazid in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199023 (65.71)18.7374
1990's7 (20.00)18.2507
2000's5 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Javid, MJ; Stone, WE1
Costa, E; Guidotti, A; Mao, CC; Suria, A1
Guidotti, A; Kurosawa, A; Naik, SR1
Dinnendahl, V; Gumulka, SW; Schönhöfer, PS1
Matthews, WD; McCafferty, GP1
Costa, E; Guidotti, A; Mao, CC2
Killam, KF; Rosenkranz, RP1
Galli, C; Spagnuolo, C; Terzi, C1
Peesker, SJ; Wood, JD1
Bertolini, A; Marrama, D; Sandrini, M; Vergoni, AV1
Carboni, G; Corda, MG; Frau, V; Giorgi, O; Lecca, D; Orlandi, M1
Alkana, RL; Finn, DA; Jones, BL; Kobayashi, LS; Syapin, PJ1
Hellevuo, K; Kiianmaa, K; Korpi, ER1
DiMicco, JA; Shekhar, A1
Laporte, AM; Soubrié, P; Thiébot, MH1
Bernasconi, R; Christen, P; Hafner, T; Klein, M; Martin, P; Portet, C; Schmutz, M1
Xu, NS; Zhang, JR; Zheng, WA1
Nishino, H1
Hamon, M; Hery, F; Jobert, A; Montastruc, JL; Soubrie, P; Thiebot, MH1
Alpert, M; Triner, L; Verosky, M; Vulliemoz, Y2
Corda, MG; Costa, E; Guidotti, A1
Crider, AM; Hinko, CN; Seibert, K1
Foote, F; Gale, K1
Barberi, C; Carré, MC; Catau, G; Caubère, P; Jacque, M; Trocklé, G1
Cao, BJ; Peng, NA1
Alkana, RL; Davies, DL; Finn, DA; Jones, BL; Syapin, PJ1
Boehrer, A; Marescaux, C; Reibel, S; Simler, S; Vergnes, M1
Anic, T; Aralica, G; Dodig, G; Duplancie, B; Jelovac, N; Marovic, A; Mise, S; Perovic, D; Petek, M; Pigac, B; Prkacin, I; Rucman, R; Sebecic, B; Seiwerth, S; Sikiric, P; Slobodnjak, Z; Stancic-Rokotov, D; Turkovic, B; Ziger, T; Zoricic, I1
Buznego, MT; Pérez-Saad, H3
Bailabar, T; Bum, EN; Hiana, IR; Moto, FC; Nkainsa, LA; Rakotonirina, A; Rakotonirina, SV; Seke Etet, PF; Seyni, P; Taiwe, GS1
De Petrocellis, L; Di Marzo, V; Minei, R; Pierobon, P1

Reviews

1 review(s) available for picrotoxin and isoniazid

ArticleYear
New concepts on the mechanism of action of benzodiazepines.
    Life sciences, 1975, Jul-15, Volume: 17, Issue:2

    Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra

1975

Other Studies

34 other study(ies) available for picrotoxin and isoniazid

ArticleYear
Benzodiazepines and phenobarbital as antagonists of dissimilar chemical convulsants.
    Epilepsia, 1978, Volume: 19, Issue:4

    Topics: 3-Mercaptopropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Chlordiazepoxide; Convulsants; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Picrotoxin; Therapeutic Equivalency

1978
Possible role of gamma aminobutyric acid (GABA) in the regulation of cAMP system in rat anterior pituitary.
    Psychoneuroendocrinology, 1977, Volume: 2, Issue:3

    Topics: Aminobutyrates; Animals; Baclofen; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; Isoniazid; Isoxazoles; Male; Nipecotic Acids; Pargyline; Picrotoxin; Pituitary Gland, Anterior; Protein Kinases; Rats; Reserpine

1977
Baclofen and cerebellar cyclic GMP levels in mice.
    Pharmacology, 1979, Volume: 19, Issue:2

    Topics: Animals; Arecoline; Baclofen; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Motor Activity; Pentylenetetrazole; Picrotoxin

1979
Anticonvulsant activity of muscimol against seizures induced by impairment of GABA-mediated neurotransmission.
    Neuropharmacology, 1979, Volume: 18, Issue:11

    Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Strychnine; Synaptic Transmission

1979
Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 289, Issue:4

    Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Cerebellum; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoniazid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Strychnine

1975
Effects of intracerebroventricular administration of prostaglandins E1 and E2 on chemically induced convulsions in mice.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 209, Issue:2

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Injections, Intraventricular; Isoniazid; Male; Mice; Pentylenetetrazole; Picrotoxin; Prostaglandins E; Seizures; Strychnine

1979
Differential response of brain PGF2alpha synthesis to methionine sulfoximine in respect of other convulsant drugs.
    Pharmacological research communications, 1978, Volume: 10, Issue:6

    Topics: Animals; Brain; Convulsants; Isoniazid; Male; Methionine Sulfoximine; Picrotoxin; Prostaglandins F; Rats

1978
The anticonvulsant action of GABA-elevating agents: a re-evaluation.
    Journal of neurochemistry, 1975, Volume: 25, Issue:3

    Topics: Allyl Compounds; Aminobutyrates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hydrazines; Hydroxylamines; Hyperbaric Oxygenation; Isoniazid; Male; Mice; Pentylenetetrazole; Picrotoxin; Seizures; Stimulation, Chemical; Time Factors

1975
Repeated administration of triiodothyronine enhances the susceptibility of rats to isoniazid- and picrotoxin-induced seizures.
    Life sciences, 1992, Volume: 51, Issue:10

    Topics: Animals; Binding Sites; Cerebral Cortex; Flunitrazepam; Hippocampus; Hyperthyroidism; Isoniazid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Triiodothyronine

1992
Pentylenetetrazol-induced kindling in rats: effect of GABA function inhibitors.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: Animals; Azides; Benzodiazepines; Carbolines; GABA Antagonists; Isoniazid; Kindling, Neurologic; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Strychnine

1991
Low-level hyperbaric heliox does not affect drug-induced seizure latency in mice.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Allylglycine; Animals; Atmospheric Pressure; Convulsants; Helium; Hyperbaric Oxygenation; Isoniazid; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Myoclonus; Picrotoxin; Seizures; Time Factors

1991
Effect of GABAergic drugs on motor impairment from ethanol, barbital and lorazepam in rat lines selected for differential sensitivity to ethanol.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:2

    Topics: Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Lorazepam; Picrotoxin; Psychomotor Performance; Rats

1989
Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats.
    Neuropharmacology, 1987, Volume: 26, Issue:5

    Topics: Aggression; Animals; Bicuculline; Brain Mapping; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Posterior; Isoniazid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Synaptic Transmission

1987
Microgram doses of diazepam do not induce proconvulsant or proconflict effects in rodents.
    Psychopharmacology, 1987, Volume: 93, Issue:3

    Topics: Animals; Bicuculline; Conditioning, Operant; Diazepam; Isoniazid; Mice; Pentylenetetrazole; Picrotoxin; Punishment; Seizures

1987
Gamma-vinyl GABA: comparison of neurochemical and anticonvulsant effects in mice.
    Journal of neural transmission, 1988, Volume: 72, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Injections; Isoniazid; Mice; Osmolar Concentration; Pentylenetetrazole; Picrotoxin; Seizures; Vigabatrin

1988
[Analysis of the depressant effect of diazepam on the amplitude of phrenic nerve discharge in rabbits].
    Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:2

    Topics: Action Potentials; Animals; Blood Pressure; Cyproheptadine; Depression, Chemical; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Naloxone; Phrenic Nerve; Picrotoxin; Rabbits

1985
[Regional blood flow in the brain. II. Effects of central stimulants, convalsants and a dissociative anesthetic on regional blood flow in the brain].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:6

    Topics: Animals; Blood Pressure; Caffeine; Cats; Central Nervous System Stimulants; Cerebrovascular Circulation; Dibenzylchlorethamine; Electroencephalography; Isoniazid; Ketamine; Methamphetamine; Picrotoxin; Regional Blood Flow; Reserpine; Sulfhydryl Compounds

1973
The regulation of cyclic guanosine monophosphate in rat cerebellum: possible involvement of putative amino acid neurotransmitters.
    Brain research, 1974, Oct-25, Volume: 79, Issue:3

    Topics: Aminobutyrates; Animals; Cerebellum; Cyclic AMP; Cyclic GMP; Glutamates; Glycine; Isoniazid; Male; Monoamine Oxidase Inhibitors; Pargyline; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine

1974
Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats.
    Brain research, 1980, May-12, Volume: 189, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Diazepam; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stress, Physiological; Thiosemicarbazones

1980
Halothane effect on cGMP and control of motor activity in mouse cerebellum.
    Anesthesiology, 1981, Volume: 54, Issue:3

    Topics: Animals; Cerebellum; Cyclic GMP; Halothane; Isoniazid; Male; Mice; Motor Activity; Picrotoxin; Seizures; Strychnine

1981
Specific proconvulsant action of an imidazobenzodiazepine (RO 15-1788) on isoniazid convulsions.
    Neuropharmacology, 1982, Volume: 21, Issue:1

    Topics: Animals; Benzodiazepinones; Brain; Convulsants; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; Isoniazid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures

1982
Effect of enflurane on cerebellar cGMP and on motor activity in the mouse.
    British journal of anaesthesia, 1983, Volume: 55, Issue:1

    Topics: Animals; Cerebellar Cortex; Cyclic GMP; Dose-Response Relationship, Drug; Enflurane; Isoniazid; Male; Mice; Mice, Inbred Strains; Motor Activity; Picrotoxin

1983
Anticonvulsant activity of the nipecotic acid ester, (+/-)-m-nitrophenyl-3-piperidinecarboxylate.
    Neuropharmacology, 1984, Volume: 23, Issue:9

    Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Nipecotic Acids; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures

1984
Morphine potentiates seizures induced by GABA antagonists and attenuates seizures induced by electroshock in the rat.
    European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4

    Topics: Animals; Bicuculline; Drug Synergism; Electroshock; GABA Antagonists; Isoniazid; Male; Morphine; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains; Seizures

1983
Investigations of new structures with pharmacological activity. II: Anticonvulsant properties of benzocyclobutenols and benzocylenones.
    Life sciences, 1981, Jan-05, Volume: 28, Issue:1

    Topics: Animals; Anticonvulsants; Electroshock; Female; Isoniazid; Lethal Dose 50; Male; Mice; Motor Activity; Pentylenetetrazole; Picrotoxin; Polycyclic Compounds

1981
Magnesium valproate attenuates hyperactivity induced by dexamphetamine-chlordiazepoxide mixture in rodents.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Bicuculline; Chlordiazepoxide; Dextroamphetamine; Drug Interactions; Female; GABA-A Receptor Antagonists; Isoniazid; Mice; Motor Activity; Picrotoxin; Rats; Rats, Sprague-Dawley; Valproic Acid

1993
Effect of 12 atmospheres helium-oxygen on the response of mice to convulsant drugs.
    Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 1996, Volume: 23, Issue:1

    Topics: Allylglycine; Animals; Atmospheric Pressure; Body Temperature; Convulsants; Helium; High Pressure Neurological Syndrome; Isoniazid; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Motor Activity; Myoclonus; Oxygen; Picrotoxin

1996
Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy.
    Experimental neurology, 2000, Volume: 161, Issue:2

    Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbolines; Convulsants; Electroencephalography; Epilepsy, Absence; Frontal Lobe; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoniazid; Kainic Acid; Limbic System; Male; Parietal Lobe; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Strychnine

2000
The effect of a novel pentadecapeptide BPC 157 on development of tolerance and physical dependence following repeated administration of diazepam.
    The Chinese journal of physiology, 1999, Sep-30, Volume: 42, Issue:3

    Topics: Amino Acid Sequence; Animals; Anti-Ulcer Agents; Anticonvulsants; Antitubercular Agents; Brain Chemistry; Diazepam; Drug Interactions; Drug Tolerance; Epilepsy; Isoniazid; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Peptide Fragments; Picrotoxin; Proteins; Receptors, GABA-A; Substance Withdrawal Syndrome

1999
Acute effect of an extract of Ambrosia paniculata (Willd.) O. E. Schultz (mugwort) in several models of experimental epilepsy.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:6

    Topics: Ambrosia; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Cerebral Cortex; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Electroshock; Epilepsy; Exploratory Behavior; Isoniazid; Male; Mice; Motor Activity; Penicillins; Phytotherapy; Picrotoxin; Plant Preparations; Psychomotor Performance; Rats; Reaction Time; Time Factors; Tubocurarine

2004
Behavioral and antiepileptic effect of acute administration of the extract of the aquatic plant Echinodorus berteroi (Sprengel) Fassett (upright burhead).
    Epilepsy & behavior : E&B, 2006, Volume: 9, Issue:1

    Topics: Alismataceae; Animals; Central Nervous System; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Electroshock; Epilepsy; Isoniazid; Male; Mice; Mice, Inbred Strains; Muscle Hypotonia; Penicillins; Phytotherapy; Picrotoxin; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Stereotyped Behavior

2006
Behavioral and antiepileptic effects of acute administration of the extract of the plant Cestrum nocturnum Lin (lady of the night).
    Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:3

    Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Stimulants; Cestrum; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Exploratory Behavior; Hyperalgesia; Isoniazid; Male; Mice; Phytotherapy; Picrotoxin; Plant Extracts; Rats; Rats, Wistar; Stereotyped Behavior

2008
Validation of anticonvulsant and sedative activity of six medicinal plants.
    Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:3

    Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Hypnotics and Sedatives; Isoniazid; Male; Medicine, African Traditional; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Plants, Medicinal; Sleep Initiation and Maintenance Disorders; Stereotyped Behavior; Strychnine

2009
Arachidonic acid and eicosanoids in Hydra: possible endogenous signals involved in chemoreception and modulation of the feeding behaviour.
    Advances in experimental medicine and biology, 1997, Volume: 433

    Topics: Animals; Arachidonic Acid; Chemoreceptor Cells; Feeding Behavior; Hydra; Hydroxyeicosatetraenoic Acids; Models, Biological; Picrotoxin; Signal Transduction

1997