picrotoxin has been researched along with gamma-aminobutyric acid in 1233 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 636 (51.58) | 18.7374 |
| 1990's | 319 (25.87) | 18.2507 |
| 2000's | 210 (17.03) | 29.6817 |
| 2010's | 54 (4.38) | 24.3611 |
| 2020's | 14 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Grafe, P; Krumnikl, J; Linder, M; Schindler, L; Sonnhof, U | 1 |
| Day, NW; Wyatt, HJ | 1 |
| Segal, M | 1 |
| Burden, J; Hillhouse, EW; Jones, MT | 1 |
| Cools, AR; Janssen, HJ | 1 |
| Aghajanian, GK; Gallager, DW | 1 |
| Kerkut, GA; Piggott, SM; Walker, RJ | 1 |
| Javid, MJ; Stone, WE | 1 |
| Martin, RJ | 2 |
| Bernardo, K; Keenan, L; Koopowitz, H | 1 |
| Yessaian, NH | 1 |
| King, GA | 1 |
| Drujan, BD; Negishi, K | 1 |
| Agnoli, A; Ciancarelli, G; Forchetti, C; Pacitti, C; Scarnati, E | 1 |
| James, TA; Straughan, DW | 1 |
| Sedlácek, J | 3 |
| Hamberger, A; Sellström, A | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 2 |
| Costa, E; Guidotti, A; Mao, CC; Suria, A | 1 |
| Balashov, N; Earl, J; Large, WA | 1 |
| Dinnedahl, V; Gumulka, SW; Opmeer, FA; Schönhöfer, PS | 1 |
| McCarthy, PS; Walker, RJ; Woodruff, GN | 1 |
| Aghajanian, GK; Gallager, DW; Wang, RY | 1 |
| Georgiev, VP; Petkova-Radkova, BP | 2 |
| Grimmer, EJ; Norcross, K; Spehlmann, R | 1 |
| Koketsu, K; Shirasawa, Y | 1 |
| Aghajanian, GK; Wang, RY | 1 |
| Hashimoto, K; Imamura, H; Kimura, T | 1 |
| Enna, SJ; Snyder, SH | 1 |
| Guidotti, A; Kurosawa, A; Naik, SR | 1 |
| Kehoe, P; Meiners, B; Olsen, RW; Ticku, MK | 1 |
| Schechter, PJ; Tranier, Y | 1 |
| DeFeudis, FV | 1 |
| Frederickson, RC; McBride, WJ; Morzorati, SL; Neuss, M | 1 |
| Chappell, RL; Klingman, A | 1 |
| Levy, RA | 2 |
| Barker, JL; Macdonald, RL | 2 |
| Miller, T; Olsen, RW; Ticku, MK | 1 |
| Olsen, RW; Ticku, MK | 2 |
| Haycock, JW; Levy, WB; Olsen, RW; Ticku, MK; Van Ness, PC | 1 |
| Martin, IL; Mitchell, PR | 1 |
| Iwatsubo, K; Kondo, Y | 1 |
| Marder, E; Paupardin-Tritsch, D | 2 |
| Hendelman, WJ; Marshall, KC; Wojtowicz, JM | 1 |
| Davidoff, RA; Hackman, JC; Osorio, I | 2 |
| Georgiev, VP; Markovska, VL; Petkova, BP | 1 |
| Arbilla, S; Langer, SZ | 1 |
| Brennan, MJ; Cantrill, RC | 1 |
| Sontag, KH; Wand, P; Wolfarth, S | 1 |
| Maderdrut, JL; Oppenheim, RW; Reitzel, JL | 1 |
| Arbilla, S; Kamal, L; Langer, SZ | 1 |
| Dinnendahl, V; Gumulka, SW; Schönhöfer, PS | 1 |
| Fu, SX; Wang, LF; Zhang, SS | 1 |
| Georgiev, VP; Rawlów, A | 1 |
| Matthews, WD; McCafferty, GP | 1 |
| McKenzie, GM; Viik, K | 1 |
| Costa, E; Guidotti, A; Mao, CC | 1 |
| Parnas, I; Rahamimoff, R | 1 |
| Costa, E; Suria, A | 1 |
| Corradetti, R; Nistri, A | 1 |
| De Vries, GW; Friedman, AH | 1 |
| Pletscher, A; Saner, A | 1 |
| Stone, WE | 1 |
| Sawaki, Y; Yagi, K | 1 |
| Ciesielski, L; Kempf, E; Mack, G; Maitre, M; Mandel, P; Simler, S | 1 |
| Bonaventure, N; Haehnel, A; Roussel, G | 1 |
| Boulu, R; Lebas, M; Ngoma-Yengo, P | 1 |
| Bioulac, B; de Tinguy-Moreaud, E; Neuzil, E; Vincent, JD | 1 |
| Risley, EA; Williams, M | 1 |
| Franco, S; Schlosser, W | 2 |
| Barnes, CD; Polzin, RL | 1 |
| Javoy-Agid, F | 1 |
| Tanner, T | 1 |
| Jenner, P; Leigh, N; Marsden, CD; Reavill, C | 2 |
| Simon, P; Soubrie, P; Thiebot, MH | 1 |
| Betti, R; Cocchi, D; Frigerio, C; Krogsgaard-Larsen, P; Locatelli, V; Müller, EE; Racagni, G | 1 |
| Arancibia, S; Enjalbert, A; Fiore, L; Kordon, C; Priam, M; Ruberg, M | 1 |
| Omata, S; Yoshida, M | 1 |
| Den Breejen, EJ; Mulder, AH; Stoof, JC | 1 |
| Homma, S | 1 |
| Chéramy, A; Glowinski, J; Leviel, V; Nieoullon, A | 1 |
| Hagmüller, K; Holzer, P | 1 |
| Werman, R | 1 |
| Watanabe, T | 1 |
| Mansour, R; Myslobodsky, MS | 1 |
| György, L | 1 |
| Billingsley, M; Suria, A; Williams, J | 1 |
| Constanti, A | 2 |
| Boissier, JR; Dumont, C; Oberlander, C | 1 |
| De Montis, GM; Mulas, G; Olianas, MC; Tagliamonte, A | 1 |
| Bacino, CB; Martin, GE; Papp, NL | 1 |
| Di Chiara, G; Gessa, GL; Morelli, M; Porceddu, ML | 1 |
| Di Chiara, G; Gessa, GL; Morelli, M; Mulas, ML; Porceddu, ML | 1 |
| Aliev, MN; Kryzhanovskiĭ, GN | 1 |
| Arnt, J; Scheel-Krüger, J | 1 |
| Ackermann, RF; Engel, J; Golovchinsky, V; Myslobodsky, MS | 1 |
| Plourde, G; Tremblay, JP | 1 |
| Bolme, P; Fuxe, K | 1 |
| Besson, MJ; Giorguieff, MF; Glowinski, J; Kemel, ML | 1 |
| Greenlee, D; Olsen, RW; Ticku, MK; Van Ness, PC | 1 |
| Hori, N; Ikeda, K; Roberts, E | 1 |
| Gallagher, JP; Higashi, H; Nishi, S | 1 |
| Dóda, M; Georgiev, VP; György, L | 1 |
| Marsden, CD; Meldrum, BS; Pycock, CJ; Tarsy, D | 1 |
| Chéramy, A; Glowinski, J; Nieoullon, A | 2 |
| Eng, N; Pericić, D; Walters, JR | 1 |
| Andén, NE; Wachtel, H | 1 |
| Petrov, VI | 1 |
| Carpenter, DO; Yarowsky, J | 1 |
| Garcy, AM; Marotta, SF | 1 |
| Homma, S; Rovainen, CM | 1 |
| Gower, M; MacNeil, D; Szymanska, I | 1 |
| Kamioka, T; Matsui, Y | 1 |
| James, TA; Starr, MS | 1 |
| Georgiev, V | 1 |
| Murakami, M; Nakatani, K; Shimoda, Y | 1 |
| Okamoto, K; Sakai, Y | 3 |
| Horng, JS; Wong, DT | 1 |
| Deguchi, T; Matsui, Y | 1 |
| Backes, DJ; Guthrie, GD; Leitch, GJ; Siegman, FS | 1 |
| Demirjian, AH; Tozalakian, BV; Yessaian, NH | 1 |
| Bartholini, G; Stadler, H | 1 |
| Dacheux, RF; Frumkes, TE; Miller, RF | 1 |
| Chujo, T; Yamamoto, C; Yamashita, H | 1 |
| Nowycky, MC; Roth, RH | 1 |
| Dill, RE; Standefer, MJ | 1 |
| Bianchi, S; Consolo, S; Jori, A; Ladinsky, H | 1 |
| Altmann, H; Pickelmann, P; Steinberg, R; Ten Bruggencate, G | 1 |
| Okamoto, K; Quastel, DM; Quastel, JH | 1 |
| Kim, HJ; Routtenberg, A | 1 |
| Horton, RW; Marsden, CD; Pycock, C | 1 |
| Ben-Ari, Y; Dingledine, R; Kanazawa, I; Kelly, JS | 1 |
| Goldstein, JM; Malick, JB | 1 |
| Bloomfield, MR; Green, AR; Tordoff, AF | 1 |
| Horton, RW; Meldrum, BS; Sawaya, MC; Stephenson, JD | 1 |
| Constanti, A; Nistri, A | 2 |
| Bornstein, MB; Corrigall, WA; Crain, SM | 1 |
| Boissier, JR; Simon, P; Soubrié, P | 1 |
| Kovalev, GV; Morozov, IS; Petrov, VI | 1 |
| Gusel'nikova, KG; Ivanova, LV; Kipor, GV | 1 |
| Meldrum, BS; Stephenson, JD | 1 |
| Starr, MS | 2 |
| Marsden, CD; Meldrum, BS; Pycock, C; Tarsy, D | 1 |
| Segal, M; Sims, K; Smissman, E | 1 |
| Peesker, SJ; Wood, JD | 1 |
| Nicoll, RA | 1 |
| Ban, M; Lee, JM; Olsen, RW | 1 |
| Barbeau, A; Davidson, DL | 1 |
| Gähwiler, BH | 1 |
| Bernardi, G; Giacomini, P; Marciani, MG; Morucutti, C | 1 |
| Dobkin, J; Lichtshtein, D | 1 |
| Fedinets, P; Kent, EW | 1 |
| Hara, N; Ichinose, M; Sawada, M | 1 |
| Liu, CC; Nichols, AC; Snead, OC | 1 |
| Aloisio, A; Caravaglios, G; Ferraro, G; Iurato, L; La Grutta, V; Sabatino, M; Sardo, P | 1 |
| Dean, P; Redgrave, P | 2 |
| Nicoll, RA; Solís, JM | 2 |
| Moises, HC; Washburn, MS | 1 |
| Bijak, M; Brunner, H; Misgeld, U | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Colquhoun, L; Holden-Dye, L; Walker, RJ | 1 |
| Eguibar, JR; Jiménez, I; Quevedo, J; Rudomin, P | 1 |
| Arancibia, S; Benyassi, A; Rage, F; Tapia-Arancibia, L | 1 |
| Chen, JC; Chesler, M | 1 |
| Aoki, S; Iwamoto, M; Jino, H; Kawaguchi, A; Kurahashi, K; Oikawa, H | 1 |
| Kamermans, M; Werblin, F | 1 |
| Jones, SR; Kennedy, RT; Wightman, RM | 1 |
| Freschi, JE; Kerrison, J | 1 |
| Qian, H; Ripps, H | 1 |
| Arakawa, O; Nakahiro, M; Narahashi, T | 1 |
| Habibuddin, M; Pal, M; Pal, SP | 1 |
| Czarnecki, A; Czyzewska-Szafran, H; Jastrzebski, Z; Remiszewska, M; Wutkiewicz, M | 1 |
| Ishibashi, S; Ishii, K; Okazaki, H; Tokuda, H | 1 |
| Cattaert, D; Clarac, F; el Manira, A | 1 |
| Dutia, MB; Johnston, AR; McQueen, DS | 1 |
| Pencheva, N; Radomirov, R; Venkova, K | 1 |
| Slaughter, MM; Stockton, RA | 1 |
| Allan, AM; Draski, LJ; Mayes, GG | 1 |
| Ticku, MK | 1 |
| Denbow, DM | 1 |
| Cupello, A; Hydén, H; Palm, A; Rapallino, MV | 1 |
| Heidelberger, R; Matthews, G | 1 |
| Agmo, A; Fernández, H | 1 |
| Dreher, J; Eshel, G; Jackson, DM; Ong, J; Wong, LS | 1 |
| Kow, LM; Ogawa, S; Pfaff, DW | 1 |
| Funk, GD; Sholomenko, GN; Steeves, JD | 1 |
| Long, SK; van Wilgenburg, H; Wesselman, JP | 1 |
| Agmo, A; Gutiérrez, M; Guzmán, M; Pruneda, R | 1 |
| Pockett, S; Slack, JR | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ; Ward, RA | 1 |
| Bonanno, G; Fedele, E; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Gillis, RA; Rossiter, CD; Travagli, RA; Vicini, S | 1 |
| Davidoff, RA; Hackman, JC | 1 |
| Shreve, PE; Uretsky, NJ | 2 |
| Aram, JA; Michelson, HB; Wong, RK | 1 |
| DiMicco, JA; Soltis, RP | 1 |
| Kubota, M; Saito, N | 1 |
| Ichihara, K; Kameyama, T; Nabeshima, T; Tohyama, K | 1 |
| Boelen, MK; Chubb, IW; Dowton, M; Morgan, IG; Wellard, J | 1 |
| Aceves, J; Arias-Montaño, JA; Martínez-Fong, D | 1 |
| Bowman, JW; Lee, BL; Thompson, DP; Whaley, HA | 1 |
| Bloomquist, JR; Grubs, RE; Knipple, DC; Soderlund, DM | 1 |
| Cook, BJ; Cooper, JF; Wagner, RM | 1 |
| Bierkamper, GG; Smith, KA | 1 |
| Kaneko, A; Suzuki, S; Tachibana, M | 1 |
| Allen, TG; Burnstock, G | 1 |
| Baur, R; Malherbe, P; Möhler, H; Sigel, E; Trube, G | 1 |
| Lothman, EW; Stringer, JL | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 1 |
| Kaila, K; Pasternack, M; Rydqvist, B; Voipio, J | 1 |
| Aliev, NA | 1 |
| Alkon, DL; Matzel, LD | 1 |
| Acs, Z; Makara, GB; Zsom, L | 1 |
| Isenberg, KE; Yang, J; Zorumski, CF | 1 |
| Liljequist, S | 1 |
| Uretsky, NJ; Wallace, LJ | 1 |
| Austin, MC; Hagler, H; Kalivas, PW; Klitenick, MA | 1 |
| Araki, H; Sano, M; Shimada, C; Tanaka, S | 1 |
| Ekström, P; Meissl, H | 1 |
| Katz, BJ; Oakley, B; Wen, R; Xu, ZA; Zheng, JB | 1 |
| McIntyre, T; Skolnick, P | 1 |
| Antonarakis, SE; Cutting, GR; Donovan, DM; Guggino, WB; Kasch, LM; Lu, L; Montrose-Rafizadeh, C; O'Hara, BF; Shimada, S; Uhl, GR | 1 |
| Darlington, CL; Hubbard, JI; Smith, PF | 1 |
| Batini, C; Billard, JM | 1 |
| Felder, RB; Feldman, PD | 1 |
| Mel'nik, IV | 1 |
| Gatti, PJ; Gillis, RA | 1 |
| Arnoldi, A; Bonsignori, A; Melloni, P; Merlini, L; Quadri, ML; Varasi, M | 1 |
| Dillon, GH; Shonis, CA; Waldrop, TG | 1 |
| Belcheva, S; Kupenova, P; Mitova, L; Vitanova, L | 1 |
| Arata, A; Homma, I; Onimaru, H | 1 |
| Penchev, A; Popova, E | 1 |
| Iasnetsov, VS; Sizov, PI | 1 |
| Okada, Y; Shibata, Y; Tomita, H | 1 |
| Arancibia, S; Briozzo, P | 1 |
| Atsuta, Y; Garcia-Rill, E; Ishikawa, Y; Kinjo, N; Skinner, RD; Webber, M | 1 |
| Boeijinga, PH; Lopes da Silva, FH; Pennartz, CM | 1 |
| Anton, RF; Becker, HC | 1 |
| Capper, HR; Johnston, GA; Kerr, DI; Ong, J | 1 |
| Kotak, VC; Page, CH | 1 |
| Akaike, N; Nakagawa, T; Nakaye, T; Shirasaki, T; Wakamori, M | 1 |
| Bray, GA; Tsujii, S | 1 |
| Alhaider, AA; Lei, SZ; Wilcox, GL | 1 |
| Sun, LS; Sun, QX; Tu, YJ; Wu, HB; Xiao, J | 1 |
| Becquet, D; Faudon, M; Hery, F | 1 |
| Coulter, DA; Huguenard, JR; Prince, DA | 1 |
| Depaulis, A; Kempf, E; Liu, Z; Marescaux, C; Vergnes, M | 1 |
| Krishnamoorthy, MS; Paul, V | 1 |
| Aksent'ev, SB; Levinskiĭ, MV | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 2 |
| Basille, C; Cazin, L; Jenks, BG; Louiset, E; Tonon, MC; van de Put, FH; Vaudry, H | 1 |
| Baur, R; Malherbe, P; Mohler, H; Persohn, E; Richards, JG; Sigel, E | 1 |
| Collingridge, GL; Davies, CH; Davies, SN | 1 |
| Friedman, DL; Redburn, DA | 1 |
| Batueva, IV; Suderevskaia, EI | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Mehta, AK; Ticku, MK | 2 |
| Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M | 1 |
| Artemenko, DP; Gerasimov, VD | 1 |
| Barnard, EA; Darlison, MG; Djamgoz, MB; Fraser, SP; O'Brien, J; Usherwood, PN | 1 |
| Mangat, HK; Rattan, AK | 3 |
| Malchow, RP; Ripps, H | 1 |
| Slater, NT; Smith, RD; Turek, FW | 1 |
| Cupello, A; Hydén, H; Rapallino, MV | 2 |
| Hong, SP; Kim, SB; Kim, WS; Lee, SI; Lee, SK; Lim, DY; Suh, J; Yoo, HJ | 1 |
| Carlen, PL; Spigelman, I; Zhang, L | 1 |
| Dhatt, RK; Mangat, HK; Rattan, AK | 3 |
| Itoh, J; Kameyama, T; Nabeshima, T; Noda, Y; Tohyama, K | 1 |
| Covey, DF; Ferrendelli, JA; Holland, KD; Rothman, SM | 1 |
| Depaulis, A; Liu, Z; Marescaux, C; Micheletti, G; Vergnes, M; Warter, JM | 1 |
| Akaike, N; Ishizuka, S; Yasui, S | 1 |
| Inoue, M; Matsuo, T; Ogata, N | 2 |
| Allan, AM; Harris, RA | 2 |
| Blaxter, TJ; Carlen, PL; Davies, MF; Kujtan, PW | 1 |
| Armstrong, WE; Sladek, CD | 1 |
| Geyer, MA; Lee, EH; Tang, YP; Wang, FB | 1 |
| David, JA; Pinnock, RD; Sattelle, DB; Wafford, KA | 1 |
| Baker, K; Clifford, DB; Covey, DF; Yang, J; Zorumski, CF | 2 |
| Lux, HD; Misgeld, U; Müller, W | 1 |
| Fukuda, H; Matsumoto, K; Ono, H; Yamazaki, J | 1 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Baur, R; Malherbe, P; Möhler, H; Sigel, E | 1 |
| Franke, C; Hatt, H; Zufall, F | 1 |
| Kaila, K; Pasternack, M; Saarikoski, J; Voipio, J | 1 |
| Callaway, JC; Stuart, AE | 1 |
| Dudek, BC; Phillips, TJ | 1 |
| Aley, KO; Kulkarni, SK | 1 |
| Hellevuo, K; Kiianmaa, K; Korpi, ER | 1 |
| Popova, E | 2 |
| Baur, R; Peter, AB; Sigel, E; Yao, Y | 1 |
| Barbier, AJ; Guenaneche, F; Lefebvre, RA | 1 |
| Kerr, DI; Ong, J | 2 |
| Bowen, DM; Cross, AJ; Francis, PT; Green, AR; Robinson, TN; Stirling, JM | 1 |
| Georgiev, V; Kambourova, T; Yonkov, D | 1 |
| Giuliani, S; Maggi, CA; Meli, A; Santicioli, P; Selleri, S | 1 |
| Candura, SM; Crema, A; Frigo, GM; Manzo, L; Onori, L; Rizzi, CA; Tonini, M | 1 |
| Kostowski, W; Płaźnik, A; Stefański, R | 1 |
| Cottrell, GA; Lambert, JJ; Peters, JA | 1 |
| Gal'chenko, AA; Iarkov, AV; Kovalev, GI; Vorob'ev, VV | 1 |
| Bezemer, R; Cools, AR; Cuypers, E; Groenewegen, H; Jaspers, R; Spooren, W | 1 |
| Ben-Ari, Y; Cherubini, E; Corradetti, R; Gaiarsa, JL | 1 |
| Asamizu, N | 1 |
| Abdul-Ghani, AS; el-Lati, S; Ghneim, H; Saca'an, A | 1 |
| Akaike, N; Carpenter, DO; Hattori, K; Oomura, Y | 1 |
| Cooper, SJ; Estall, LB | 1 |
| Caligaris, L; Haymal, B; Morello, H; Taleisnik, S | 1 |
| Bayardo, F; Buzsáki, G; Gage, FH; Ponomareff, GL; Ruiz, R | 1 |
| Fukuda, H; Ishikawa, M; Miyazaki, H | 1 |
| Clement, ME; McCall, RB | 2 |
| Pan, ZZ; Williams, JT | 1 |
| Bauer, RM; Waldrop, TG | 1 |
| Castellano, C; Introini-Collison, IB; McGaugh, JL; Pavone, F | 1 |
| Alabadí, JA; Alborch, E; Campos, V; Miranda, FJ; Salom, JB; Torregrosa, G | 1 |
| Carter, DA; Lightman, SL; Saridaki, E | 1 |
| Cardinali, DP; Rosenstein, RE; Sanjurjo, C | 1 |
| Evans, RH; Krijzer, F; Long, SK | 1 |
| Aston-Jones, G; Ennis, M | 1 |
| Palermo-Neto, J; Sandoval, MR | 1 |
| Austin, MC; Kalivas, PW | 1 |
| Krsiak, M | 1 |
| Nakamura, J; Sasa, M; Takaori, S | 1 |
| Kirsch, M; Wagner, HJ | 1 |
| Hillhouse, EW; Milton, NG | 1 |
| Li, DX; Shen, GS; Wang, Y | 1 |
| Akaike, N; Carpenter, DO; Tokutomi, N; Yakushiji, T | 2 |
| Asaro, D; Pellegrini, G; Pittaluga, A; Raiteri, M | 1 |
| Maggi, CA; Meli, A; Santicioli, P | 4 |
| Castellano, C; Pavone, F | 1 |
| Maksay, G; Simonyi, M | 1 |
| Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC | 1 |
| Barnard, EA; Blair, LA; Dionne, VE; Levitan, ES; Marshall, J | 1 |
| Hara, S; Morioka, S; Satoh, K; Yanagihara, S | 1 |
| Connors, BW; Malenka, RC; Silva, LR | 1 |
| Iasnetsov, VS; Novikov, VE | 1 |
| Gallager, DW; Tallman, JF | 1 |
| Bhargava, KP; Gupta, GP; Gupta, MB | 1 |
| Hata, H; Kido, N; Nakamura, T; Ohnishi, T; Tonoue, T | 1 |
| Chan, CY; Farb, DH | 1 |
| Peterfreund, RA; Vale, WW | 1 |
| Handley, SL; Heaton, JC; Rea, PJ; Singh, L | 1 |
| Brownlee, RD; Brudzynski, SM; Houghton, PE; Mogenson, GJ | 1 |
| Nistri, A; Sivilotti, L | 2 |
| Gross, RA; Macdonald, RL; Weddle, MG | 1 |
| Kent, AP; Webster, RA | 1 |
| Dingledine, R; King, GL | 1 |
| Boakes, RJ; Hardy, JA; Turner, JD; Virmani, MA | 1 |
| Fujiwara, M; Kurahashi, K; Okamoto, T; Tsubomura, T | 2 |
| Hamon, M | 1 |
| Koe, BK; Kondratas, E; Russo, LL | 1 |
| Garg, SK; Kulkarni, SK; Shukla, VK | 1 |
| McGarrick, JD; Stone, TW; Thexton, AJ | 1 |
| Lakić, N; Manev, H; Pericić, D | 1 |
| Boussaoud, D; Joseph, JP | 1 |
| Dichter, MA; Snodgrass, SR; White, WF | 1 |
| Rastogi, SK; Ticku, MK | 1 |
| Massey, SC; Redburn, DA | 2 |
| Hesse, GW; Jacob, JN; Shashoua, VE | 2 |
| George, SR; Meissl, H | 1 |
| Maggi, CA; Manzini, S; Meli, A | 1 |
| Giotti, A; Luzzi, S; Maggi, CA; Spagnesi, S; Zilletti, L | 1 |
| Humphrey, SJ; McCall, RB | 2 |
| Ho, IK; Sivam, SP | 2 |
| Scholfield, CN; Steel, L | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Lelekova, TV; Serbeniuk, TsV | 2 |
| Abramets, II; Komissarov, IV | 2 |
| Chweh, AY; Swinyard, EA; Ulloque, RA; Wolf, HH | 1 |
| Georgiev, VP; Yonkov, DI | 1 |
| Durán, JA; Miñano, FJ; Sancibrián, M; Serrano, JS | 1 |
| Bloomquist, JR; Soderlund, DM | 1 |
| Agardh, E | 1 |
| Dewhurst, DG | 1 |
| Carrer, HF; Mascó, D; Weigel, R | 1 |
| Beyer, C; Fernández-Guasti, A; Larsson, K | 2 |
| Culp, S; Liljequist, S; Tabakoff, B | 1 |
| Blessing, WW; Jervois, PM; Menadue, MF; Willoughby, JO | 1 |
| Garcha, HS; Rose, IC; Stolerman, IP | 1 |
| Scheel-Krüger, J | 1 |
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| Israel, JM; Oliet, SH; Poulain, DA | 1 |
| Pericić, D; Strac, DS; Vlainić, J | 1 |
| Akabas, MH; Bali, M; Jansen, M | 1 |
| Choi, SY; Choi, UK; Kang, JH; Kang, TC; Kim, DW; Kim, HT; Kim, JE; Kwak, SE; Kwon, OS; Lee, SJ | 1 |
| de Lima, AD; Klueva, J; Meis, S; Munsch, T; Voigt, T | 1 |
| Ishii, H; Kato, M; Sakuma, Y; Tanaka, N; Yin, C | 1 |
| Chang, Y; Xue, F; Zhang, J | 1 |
| Ernest, NJ; Habela, CW; Sontheimer, H; Swindall, AF | 1 |
| Czajkowski, C; Jackson, MB; Muroi, Y; Theusch, CM | 1 |
| Di Cosmo, A; Di Cristo, C; Moccia, F; Winlow, W | 1 |
| Duch, C; Evers, JF; Meseke, M | 1 |
| Cox, PJ; Güçlü, B; Mahoney, GK; Pack, AK; Pawson, L; Prestia, LT | 1 |
| Antognini, JF; Atherley, RJ; Jinks, SL; Kim, J; Kungys, G | 1 |
| Bosma, MM; Kirkman, JL; Rockhill, W | 1 |
| Charles, JR; Ebersole, PL; Htut, MH; Lara, RN; Ngo, PT; Stanley, BG; Tsai, DH; Turenius, CI | 1 |
| Benes, FM; Berretta, S; Gisabella, B | 1 |
| Ito, K; Stopfer, M; Tanaka, NK | 1 |
| Héja, L; Kardos, J; Lasztóczi, B; Nyitrai, G | 1 |
| Akk, G; Bracamontes, J; Khatri, A; Li, P; Steinbach, JH; Weiss, DS | 1 |
| Nogueira, CW; Prigol, M; Wilhelm, EA; Zeni, G | 1 |
| Aguilar, J; Bautista, W; Delgado-Lezama, R; Loeza-Alcocer, JE | 1 |
| Kosterin, P; Obaid, AL; Salzberg, BM | 1 |
| El Idrissi, A; L'Amoreaux, WJ; Marsillo, A | 1 |
| Jacobson, G; Melin, S; Sleigh, JW; Voss, LJ | 1 |
| Cao, X; Li, P; Mercaldo, V; Wu, LJ; Zhuo, M | 1 |
| Burdakov, D; Fugger, L; Jensen, LT; Karnani, MM; Venner, A | 1 |
| Mozrzymas, JW; Urban-Ciecko, J | 1 |
| Kumar, A; Kumar, P; Singh, A | 1 |
| Arima-Yoshida, F; Manabe, T; Watabe, AM | 1 |
| Centeno, M; Gallagher, JP; Genzer, K; Krishnan, B; Liu, J; Orozco-Cabal, L; Pollandt, S; Schmidt, K; Shinnick-Gallagher, P; Sun, A; Xia, Y | 1 |
| Gao, JX; Jiang, YX; Yan, L; Yang, G; Yi, ZH | 1 |
| Puente, MA; Ritta, MN; Tartaglione, CM | 1 |
| Doretto, MC; Drumond, LE; Guidine, PA; Kushmerick, C; Massensini, AR; Moraes, MF | 1 |
| Borgius, L; Dougherty, KJ; Endo, T; Hägglund, M; Hnasko, TS; Kiehn, O; Löw, P; Ryge, J; Talpalar, AE | 1 |
| Carlson, BA; George, AA; Lyons-Warren, AM; Ma, X | 1 |
| Brown, DD; Forrester, SG; Kaji, MD; Siddiqui, SZ | 1 |
| Baptista-Hon, DT; Deeb, TZ; Gallacher, M; Hales, TG; Othman, NA; Perry, DC | 1 |
| Dierkes, PW; Kilb, W; Kolbaev, SN; Luhmann, HJ; Sharopov, S | 1 |
| Gao, J; Jia, Y; Jiang, Y; Yan, L; Yang, G; Yu, J | 1 |
| Baines, RA; Günay, C; Lin, WH; Marley, R; Prinz, AA | 1 |
| Kamal, SM | 1 |
| Endeman, D; Fahrenfort, I; Kamermans, M; Sjoerdsma, T; Steijaert, M; Ten Eikelder, H | 1 |
| Armengaud, C; Boumghar, K; Couret-Fauvel, T; Garcia, M | 1 |
| Enjin, A; Eriksson, A; Gezelius, H; Kullander, K; Leão, KE; Leão, RN; Loew, LM; Mikulovic, S; Munguba, H; Patra, K; Tort, AB | 1 |
| Dacks, AM; Weiss, KR | 1 |
| Bai, Y; Chang, F; Chen, F; Chen, L; Zhou, R | 1 |
| Ahangar, N; Ebrahimzadeh, MA; Nabavi, SF; Nabavi, SM | 1 |
| Caballero, A; Cass, DK; Flores-Barrera, E; Thomases, DR; Tseng, KY | 1 |
| Aitta-Aho, T; den Hollander, B; Korpi, ER; Manner, AK; Uusi-Oukari, M; Vashchinkina, E; Vekovischeva, O | 1 |
| Cho, DH; Han, SK; Park, SJ; Yin, H | 1 |
| Ferreri, MC; Gravielle, MC; Gutiérrez, ML | 1 |
| Brame, LS; Cao, A; Fang, YT; Fung, KM; Humphreys, MR; Kropp, BP; Lin, HK; Shih, PT; Wu, W; Yang, Q | 1 |
| Gassel, M; Ilg, T; Noack, S; Williams, H; Wolf, C | 1 |
| Underwood, E | 1 |
| Harvey, J; Palmer, MJ | 1 |
| Glinka, Y; Hasilo, C; Paraskevas, S; Prud'homme, GJ; Udovyk, O; Wang, Q | 1 |
| Alqazzaz, M; Lummis, SC; Price, KL; Thompson, AJ; Weston, DA | 1 |
| Feuerstein, TJ; Heida, T; Hofmann, UG; Moser, A; Stegenga, J; Tronnier, V; Xie, Y; Zhao, Y | 1 |
| Connors, BW; Crandall, SR; Cruikshank, SJ | 1 |
| Engin, E; Keist, R; Laha, KT; Pearce, RA; Rodgers, FC; Rudolph, U; Zarnowska, ED; Zeller, A | 1 |
| Allio, A; Calorio, C; Carbone, E; Franchino, C; Gavello, D; Marcantoni, A | 1 |
| Khan, T; Kim, YY; Shehzad, A; Shehzad, O; Wahid, F | 1 |
| Baines, RA; Fan, YN; Masullo, L; Streit, AK | 1 |
| Hanaoka, K; Ikegaya, Y; Komatsu, T; Matsuki, N; Nagano, T; Naka, M; Nomura, H; Takeda, A; Terai, T; Ueno, T; Urano, Y | 1 |
| Ago, Y; Hasebe, S; Hashimoto, H; Hiramatsu, N; Matsuda, T; Mori, K; Onaka, Y; Takuma, K; Watabe, Y | 1 |
| Hassel, JE; Lowry, CA; Spiacci, A; Yamashita, PS; Zangrossi, H | 1 |
| Dembitskaya, Y; Fino, E; Gangarossa, G; Paillé, V; Perez, S; Valtcheva, S; Venance, L | 1 |
| Shimizu, K; Stopfer, M | 1 |
| Czajkowski, C; Ghosh, B; Tsao, TW | 1 |
| Bonsi, P; De Jaco, A; Martella, G; Meringolo, M; Pisani, A; Trobiani, L | 1 |
| Kaneko, M; Kobayashi, M; Murayama, S; Ogiso, B; Yamamoto, K | 1 |
| Avoli, M; Cataldi, M; Chen, LY; Lévesque, M | 1 |
| Jin, Y; Li, Y; Liu, Y; Sun, F; Yang, S; Zhang, J; Zhou, J; Zhu, K | 1 |
| Göpfert, MC; Gubert, S; Knorr, DY; Stumpner, A | 1 |
| Aihara, K; Hirata, Y; Hoang, H; Kawato, M; Lang, EJ; Schweighofer, N; Tokuda, IT; Toyama, K | 1 |
| Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y | 1 |
| Bae, JY; Bae, YC; Cheong, E; Choi, JW; Feng, J; Ha, GE; Kim, KH; Kim, S; Kim, YS; Koh, W; Kwak, H; Kwon, SW; Lee, CJ; Lee, D; Lee, EH; Lee, H; Lee, J; Lee, JM; Lee, SE; Li, Y; Oh, JE; Park, KD; Park, YM; Shin, JI; Son, T; Song, K; Woo, J; Yoon, BE | 1 |
| Garcia, V; Voss, LJ | 1 |
| Goodchild, J; Lansdell, SJ; Millar, NS; Puinean, AM; Sanders, VR; Smelt, CLC | 1 |
| Ahn, Y; Cho, HJ; Jo, K; Kwak, WK; Min, B; Suh, HJ | 1 |
| Belgardt, BF; Eckel, J; Hasse, B; Koopmans, G; Roden, M; Rohbeck, E; Romacho, T; Romero, A | 1 |
| Arnold, LA; Emala, CW; Perez-Zoghbi, JF; Sajorda, DR; Webb, DA; Yocum, GT | 1 |
| Nimitvilai-Roberts, S; Woodward, JJ | 1 |
| Mallick, BN; Mishra, Y | 1 |
| Georgiyants, V; Kayal, WE; Mishchenko, M; Severina, H; Shtrygol, D; Shtrygol, S; Zalevskyi, S | 1 |
| Cowgill, J; Fan, C; Haloi, N; Howard, RJ; Lindahl, E; Tobiasson, V; Zhuang, Y | 1 |
23 review(s) available for picrotoxin and gamma-aminobutyric acid
| Article | Year |
|---|---|
GABA and central monoamine release.
Topics: Adrenal Glands; Aminooxyacetic Acid; Animals; Bicuculline; Biogenic Amines; Calcium; Cats; Central Nervous System; Chromaffin System; Corpus Striatum; Dogs; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Hypothalamus; Magnesium; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Serotonin; Synaptic Transmission; Thalamus | 1978 |
Inhibitory mechanisms in the substantia nigra and the dopamine pathway.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Brain Mapping; Cats; Corpus Striatum; Cyclohexanecarboxylic Acids; Dopamine; Electrophysiology; Ethanolamines; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Homovanillic Acid; Hydroxydopamines; Mice; Motor Activity; Muscimol; Neural Inhibition; Neural Pathways; Oxidopamine; Picrotoxin; Rats; Substantia Nigra | 1979 |
New concepts on the mechanism of action of benzodiazepines.
Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra | 1975 |
GABA-receptors in the vertebrate nervous system.
Topics: Action Potentials; Aging; Aminobutyrates; Animals; Bicuculline; Brain; Cats; Cerebellar Cortex; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Mice; Neural Inhibition; Picrotoxin; Rats; Receptors, Neurotransmitter; Social Isolation; Sodium; Spinal Cord; Structure-Activity Relationship | 1977 |
The role of GABA in primary afferent depolarization.
Topics: Aminobutyrates; Animals; Axons; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Neural Pathways; Neurons, Afferent; Picrotoxin; Potassium; Serotonin Antagonists; Spinal Cord; Substantia Gelatinosa; Synapses; Synaptic Transmission | 1977 |
Electrophysiological characteristics of identified tubero-infundibular neurons.
Topics: Action Potentials; Animals; Catecholamines; Electrophysiology; Female; gamma-Aminobutyric Acid; Hypothalamus; Interneurons; Lighting; Male; Median Eminence; Neural Inhibition; Neural Pathways; Neurons; Neurons, Efferent; Ovulation; Picrotoxin; Preoptic Area; Rats; Refractory Period, Electrophysiological | 1978 |
Behavioural consequences of manipulating GABA neurotransmission in the superior colliculus.
Topics: Animals; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Motor Activity; Muscimol; Neurons, Afferent; Neurons, Efferent; Picrotoxin; Rats; Superior Colliculi; Synaptic Transmission | 1992 |
Effect of GABAergic and glutamatergic drugs injected into the ventral pallidum on locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Ibotenic Acid; Kainic Acid; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin | 1991 |
[GABA receptor complex and the mechanisms of action of various anticonvulsants (review of the literature)].
Topics: Animals; Anticonvulsants; Barbiturates; Brain; Drug Evaluation; Epilepsy; gamma-Aminobutyric Acid; Humans; Picrotoxin; Rats; Receptors, GABA-A | 1990 |
Behavioural pharmacology of food, water and salt intake in relation to drug actions at benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Appetite; Appetite Depressants; Benzodiazepines; Benzodiazepinones; Carbolines; Chlordiazepoxide; Chlorides; Choice Behavior; Diazepam; Drinking Behavior; Feeding Behavior; Flumazenil; Food Deprivation; Food Preferences; gamma-Aminobutyric Acid; Ion Channels; Midazolam; Picrotoxin; Punishment; Pyrazoles; Receptors, GABA-A; Satiation; Sodium Chloride; Species Specificity | 1985 |
The GABA-ergic system: a locus of benzodiazepine action.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Brain Chemistry; Carbolines; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Humans; Molecular Conformation; Picrotoxin; Rats; Receptors, GABA-A; Synaptic Transmission | 1985 |
[GABA receptors in the central nervous system. Biochemical and pharmacological aspects].
Topics: Allosteric Site; Animals; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; gamma-Aminobutyric Acid; Humans; Muscimol; Picrotoxin; Receptors, GABA-A | 1987 |
GABA in morphine analgesia and tolerance.
Topics: Analgesia; Animals; Baclofen; Benzodiazepines; Bicuculline; Brain Chemistry; Cyclohexanecarboxylic Acids; Drug Tolerance; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Morphine; Muscimol; Naloxone; Picrotoxin; Rats; Receptors, GABA-A; Synaptic Transmission | 1985 |
Convulsant and anticonvulsant drug binding sites related to GABA-regulated chloride ion channels.
Topics: Animals; Anticonvulsants; Barbiturates; Binding Sites; Brain Chemistry; Chlorides; Convulsants; gamma-Aminobutyric Acid; Humans; Ion Channels; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
GABA-benzodiazepine-barbiturate receptor interactions.
Topics: Animals; Barbiturates; Benzodiazepines; Brain; gamma-Aminobutyric Acid; Kinetics; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Sesterterpenes | 1981 |
The GABA postsynaptic membrane receptor-ionophore complex. Site of action of convulsant and anticonvulsant drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Bicuculline; Brain; Chlorides; Convulsants; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Seizures; Synaptic Membranes | 1981 |
Drug interactions at the GABA receptor-ionophore complex.
Topics: Animals; Barbiturates; Benzodiazepines; Brain; Drug Interactions; gamma-Aminobutyric Acid; Ion Channels; Ionophores; Models, Biological; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1982 |
Anterior pituitary GABA receptors in relation to prolactin secretion.
Topics: Animals; Diestrus; Estradiol; Female; gamma-Aminobutyric Acid; Lactation; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Pregnancy; Prolactin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Amino acids and presynaptic inhibition.
Topics: Amino Acids; Animals; Evoked Potentials; gamma-Aminobutyric Acid; Motor Neurons; Nerve Endings; Neural Inhibition; Neurons; Neurons, Afferent; Picrotoxin; Sodium; Synapses | 1981 |
[The clinical pharmacology of the GABAergic system (I)].
Topics: Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; gamma-Aminobutyric Acid; Humans; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission | 1994 |
Gamma hydroxybutyrate is not a GABA agonist.
Topics: 4-Butyrolactone; Animals; Central Nervous System; Convulsants; Electroencephalography; GABA Agonists; gamma-Aminobutyric Acid; Humans; Mammals; Muscle Contraction; Picrotoxin; Rabbits; Rats; Receptors, GABA; Respiration; Seizures; Sodium Oxybate | 1996 |
Molecular and functional diversity of the expanding GABA-A receptor gene family.
Topics: Benzodiazepines; Binding Sites; Chromosomes, Human; Conserved Sequence; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Models, Molecular; Picrotoxin; Receptors, GABA-A; Sequence Homology, Amino Acid | 1999 |
Methodological approaches for the study of GABA(A) receptor pharmacology and functional responses.
Topics: Binding Sites; Electrophysiology; GABA Agents; gamma-Aminobutyric Acid; Ion Channels; Models, Biological; Picrotoxin; Receptors, GABA-A | 2003 |
1210 other study(ies) available for picrotoxin and gamma-aminobutyric acid
| Article | Year |
|---|---|
Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord.
Topics: Alanine; Amino Acids; Animals; Anura; Depression, Chemical; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Motor Neurons; Neural Inhibition; Neurotransmitter Agents; Picrotoxin; Rana esculenta; Spinal Cord; Spinal Nerve Roots; Stereoisomerism; Strychnine; Synaptic Membranes; Taurine | 1975 |
Specific effects of neurotransmitter antagonists on ganglion cells in rabbit retina.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Glycine; Neurotransmitter Agents; Picrotoxin; Rabbits; Retina; Strychnine | 1976 |
5-HT antagonists in rat hippocampus.
Topics: Acetylcholine; Animals; Bicuculline; Cinanserin; Cyproheptadine; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Lysergic Acid Diethylamide; Male; Methiothepin; Methysergide; Mianserin; Norepinephrine; Picrotoxin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical | 1976 |
Effect on various putative neurotransmitters on the secretion of corticotrophin-releasing hormone from the rat hypothalamus in vitro-a model of the neurotransmitters involved.
Topics: Acetylcholine; Animals; Atropine; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hexamethonium Compounds; Hypothalamus; In Vitro Techniques; Male; Melatonin; Methysergide; Models, Biological; Neurotransmitter Agents; Norepinephrine; Phentolamine; Picrotoxin; Rats; Serotonin; Serotonin Antagonists | 1976 |
gamma-Aminobutyric acid: the essential mediator of behaviour triggered by neostriatally applied apomorphine and haloperidol.
Topics: Aminobutyrates; Animals; Apomorphine; Behavior, Animal; Cats; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Male; Picrotoxin; Substantia Nigra | 1976 |
Effect of antipsychotic drugs on the firing of dorsal raphe cells. II. Reversal by picrotoxin.
Topics: Animals; Antipsychotic Agents; Depression, Chemical; gamma-Aminobutyric Acid; Glycine; Male; Picrotoxin; Rats; Receptors, Adrenergic; Receptors, Serotonin; Reticular Formation; Strychnine; Synaptic Transmission | 1976 |
The actions of picrotoxin, strychnine, bicuculline and other convulsants and antagonists on the responses to acetylcholine glutamic acid and gamma-aminobutyric acid on Helix neurones.
Topics: Acetylcholine; Aminobutyrates; Animals; Anticonvulsants; Bicuculline; Brain; Convulsants; gamma-Aminobutyric Acid; Glutamates; Helix, Snails; Isoquinolines; Neurons; Picrotoxin; Strychnine | 1977 |
Benzodiazepines and phenobarbital as antagonists of dissimilar chemical convulsants.
Topics: 3-Mercaptopropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Chlordiazepoxide; Convulsants; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Picrotoxin; Therapeutic Equivalency | 1978 |
Glycine and GABA receptors on lamprey bulbar reticulospinal neurones.
Topics: Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Fishes; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Lampreys; Membrane Potentials; Neurons; Picrotoxin; Receptors, Drug; Stimulation, Chemical; Strychnine | 1978 |
Primitive nervous systems: action of aminergic drugs and blocking agents on activity in the ventral nerve cord of the flatworm Notoplana acticola.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Neurons; Neurotransmitter Agents; Pentylenetetrazole; Peripheral Nerves; Picrotoxin; Platyhelminths | 1979 |
Effects of systemically applied GABA agonists and antagonists on wave-spike ECoG activity in rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Electroencephalography; Epilepsy, Absence; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Male; Muscimol; Photic Stimulation; Picrotoxin; Rats; Strychnine | 1979 |
Effects of some amino acids on horizontal cells in the fish retina.
Topics: Amino Acids; Animals; Aspartic Acid; beta-Alanine; Fishes; gamma-Aminobutyric Acid; Glutamates; Glycine; Membrane Potentials; Photoreceptor Cells; Picrotoxin; Retina; Taurine | 1979 |
Electrophysiological and behavioural correlations during the manipulations of GABA functions in the substantia nigra by n-dipropylacetate and picrotoxin.
Topics: Animals; Brain Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; Male; Motor Activity; Picrotoxin; Rats; Substantia Nigra; Time Factors; Valproic Acid | 1979 |
The development of spontaneous motility in chick embryos interaction of picrotoxin and GABA.
Topics: Aminobutyrates; Animals; Cell Movement; Chick Embryo; Drug Antagonism; gamma-Aminobutyric Acid; Motor Activity; Picrotoxin; Time Factors | 1977 |
Neuronal and glial systems for gamma-aminobutyric acid transport.
Topics: Amino Acids, Diamino; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Biological Transport, Active; Calcium; Chlorpromazine; Cyclic AMP; gamma-Aminobutyric Acid; In Vitro Techniques; Neuroglia; Neurons; Picrotoxin; Potassium; Rabbits; Sodium; Strychnine; Synaptosomes; Tritium | 1975 |
Studies on convulsants in the isolated frog spinal cord. II. Effects on root potentials.
Topics: Action Potentials; Alanine; Animals; Bicuculline; Convulsants; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons, Afferent; Perfusion; Picrotoxin; Rana pipiens; Spinal Nerve Roots; Strychnine; Synapses; Synaptic Transmission; Taurine | 1975 |
Some characteristics of pre- and post-synaptic inhibitory receptors at the hermit crab neuromuscular junction.
Topics: Animals; Anomura; Depression, Chemical; Evoked Potentials; gamma-Aminobutyric Acid; Guanidines; In Vitro Techniques; Neuromuscular Junction; Picrotoxin; Propionates; Receptors, Neurotransmitter; Synaptic Membranes | 1975 |
Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain.
Topics: Animals; Atropine; Brain; Brain Chemistry; Convulsants; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Harmaline; Male; Mice; Oxotremorine; Pentobarbital; Pentylenetetrazole; Picrotoxin; Tremor | 1976 |
Studies on the pharmacology of neurones in the nucleus accumbens of the rat.
Topics: Acetylcholine; Animals; Atropine; Bucladesine; Caudate Nucleus; Dopamine; Ergonovine; Female; gamma-Aminobutyric Acid; Glycine; Homocysteine; Naphthols; Neural Inhibition; Neurons; Picrotoxin; Rats; Septal Nuclei; Septum Pellucidum; Stimulation, Chemical; Strychnine; Tetrahydronaphthalenes | 1976 |
Stimulation of pontine reticular formation suppresses firing of serotonergic neuronses in the dorsal raphe.
Topics: Action Potentials; Animals; Brain Mapping; Brain Stem; Cerebral Ventricles; Electric Stimulation; gamma-Aminobutyric Acid; Male; Neural Pathways; Picrotoxin; Rats; Reticular Formation; Serotonin; Strychnine; Synaptic Transmission; Trigeminal Ganglion | 1976 |
Effects of certain drugs connected with the system of 3',5'-cAMP on the picrotoxin convulsive-seizure threshold and on the action of GABA.
Topics: Aminobutyrates; Animals; Brain; Bucladesine; Cyclic AMP; Drug Interactions; gamma-Aminobutyric Acid; Isoproterenol; Male; Mice; Picrotoxin; Seizures | 1976 |
GABA in the caudate nucleus: a possible synaptic transmitter of interneurons.
Topics: Aminobutyrates; Animals; Cats; Caudate Nucleus; Evoked Potentials; gamma-Aminobutyric Acid; Neurons; Organ Specificity; Picrotoxin; Substantia Nigra; Synapses; Synaptic Transmission; Thalamus | 1977 |
Action of 5-hydroxytryptamine on isolated spinal cord of bullfrogs.
Topics: Animals; Anura; Calcium; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Membrane Potentials; Mephenesin; Motor Neurons; Nerve Endings; Picrotoxin; Rana catesbeiana; Serotonin; Serotonin Antagonists; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1977 |
Physiological evidence for habenula as major link between forebrain and midbrain raphe.
Topics: Action Potentials; Animals; Brain; Brain Mapping; Brain Stem; Decerebrate State; Diencephalon; Electric Stimulation; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Neural Pathways; Picrotoxin; Rats; Serotonin; Strychnine; Synaptic Transmission; Telencephalon | 1977 |
Facilitatory and inhibitory effects of gamma-aminobutyric acid on ganglionic transmission in the sympathetic cardiac nerves of the dog.
Topics: Aminobutyrates; Animals; Atropine; Dogs; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Ganglia, Autonomic; Heart; Heart Rate; Hexamethonium Compounds; Male; Phenoxybenzamine; Picrotoxin; Synaptic Transmission | 1977 |
Effect of isopropylnoradrenaline, adenosine, cyclic 3',5'-adenosinemonosphosphate and dibutyryl cyclic adenosinemonophosphate on the picrotoxin convulsive-seizure threshold. Interaction with gamma-aminobutyric acid.
Topics: Adenosine; Aminobutyrates; Animals; Bucladesine; Cyclic AMP; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; Norepinephrine; Picrotoxin; Seizures | 1976 |
GABA receptor binding in frog spinal cord and brain.
Topics: Aminobutyrates; Animals; Anura; Bicuculline; Binding Sites; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Kinetics; Picrotoxin; Rana catesbeiana; Receptors, Cell Surface; Spinal Cord | 1977 |
Possible role of gamma aminobutyric acid (GABA) in the regulation of cAMP system in rat anterior pituitary.
Topics: Aminobutyrates; Animals; Baclofen; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; Isoniazid; Isoxazoles; Male; Nipecotic Acids; Pargyline; Picrotoxin; Pituitary Gland, Anterior; Protein Kinases; Rats; Reserpine | 1977 |
Properties of gamma-aminobutyric acid receptor/ionophore proteins from crayfish muscle [proceedings].
Topics: Aminobutyrates; Animals; Astacoidea; GABA Antagonists; gamma-Aminobutyric Acid; Ionophores; Membrane Proteins; Muscles; Picrotoxin; Receptors, Neurotransmitter; Subcellular Fractions | 1977 |
Effect of elevated brain GABA concentrations on the actions of bicuculline and picrotoxin in mice.
Topics: Aminobutyrates; Animals; Bicuculline; Brain; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoquinolines; Male; Mice; Picrotoxin; Synaptic Transmission | 1977 |
A comparison of the inhibitory effects of taurine and GABA on identified Purkinje cells and other neurons in the cerebellar cortex of the rat.
Topics: Aminobutyrates; Animals; Bicuculline; Cerebellar Cortex; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Male; Neural Conduction; Neural Inhibition; Neurons; Picrotoxin; Purkinje Cells; Rats; Receptors, Neurotransmitter; Strychnine; Taurine | 1978 |
Feedback synaptic interaction in the dragonfly ocellar retina.
Topics: Animals; Bicuculline; Cockroaches; Feedback; gamma-Aminobutyric Acid; Insecta; Membrane Potentials; Models, Neurological; Neurons; Ocular Physiological Phenomena; Picrotoxin; Synapses; Synaptic Transmission; Tubocurarine; Vision, Ocular | 1978 |
Different actions of anticonvulsant and anesthetic barbiturates revealed by use of cultured mammalian neurons.
Topics: Action Potentials; Cells, Cultured; Electric Conductivity; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, Neurotransmitter | 1978 |
Dihydropicrotoxinin binding to crayfish muscle sites possibly related to gamma-aminobutyric acid receptor-ionophores.
Topics: Aminobutyrates; Animals; Astacoidea; Cell Membrane; Chlorides; Cockroaches; GABA Antagonists; gamma-Aminobutyric Acid; Houseflies; In Vitro Techniques; Muscles; Picrotoxin; Receptors, Neurotransmitter; Subcellular Fractions; Synaptic Transmission | 1978 |
Interaction of barbiturates with dihydropicrotoxinin binding sites related to the GABA receptor-ionophore system.
Topics: Aminobutyrates; Animals; Barbiturates; Binding Sites; Brain; gamma-Aminobutyric Acid; Ionophores; Male; Membranes; Picrotoxin; Rats; Receptors, Drug; Receptors, Neurotransmitter; Structure-Activity Relationship | 1978 |
Dihydropicrotoxinin binding sites in rat brain: comparison to GABA receptors.
Topics: Aging; Aminobutyrates; Animals; Binding Sites; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Microsomes; Picrotoxin; Rats; Receptors, Neurotransmitter; Synaptosomes | 1978 |
Is GABA release modulated by presynaptic receptors?
Topics: Aminobutyrates; Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Oxazoles; Picrotoxin; Potassium; Rats; Receptors, Neurotransmitter; Taurine | 1978 |
Increased release of preloaded [3H]GABA from substantia nigra in vivo following stimulation of caudate nucleus and globus pallidus.
Topics: Animals; Caudate Nucleus; Electric Stimulation; gamma-Aminobutyric Acid; Globus Pallidus; Male; Picrotoxin; Rats; Receptors, Neurotransmitter; Substantia Nigra; Tritium | 1978 |
The pharmacological properties of some crustacean neuronal acetylcholine, gamma-aminobutyric acid, and L-glutamate responses.
Topics: Acetylcholine; Animals; Brachyura; Chlorides; gamma-Aminobutyric Acid; Ganglia; Glutamates; In Vitro Techniques; Male; Membrane Potentials; Neurons; Picrotoxin; Potassium; Receptors, Cholinergic; Synaptic Transmission | 1978 |
Electrophysiological and pharmacological studies of the inhibitory projection from the cerebellar cortex to the deep cerebellar nuclei in tissue culture.
Topics: Animals; Bicuculline; Cerebellar Cortex; Cerebellar Nuclei; Culture Techniques; gamma-Aminobutyric Acid; Glycine; Mice; Neural Inhibition; Neural Pathways; Picrotoxin; Strychnine; Synaptic Transmission | 1978 |
GABA or potassium: which mediates primary afferent depolarization?
Topics: Afferent Pathways; Animals; Anura; Bicuculline; gamma-Aminobutyric Acid; Neurons, Afferent; Picrotoxin; Potassium; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission | 1979 |
Apomorphine stereotypies and transmitter mechanisms in the striatum. I. Changes in the apomorphine stereotypies caused by drugs acting on the GABA-ergic, dopaminergic and cholinergic transmission.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Behavior; Corpus Striatum; Diazepam; Ditiocarb; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Levodopa; Male; Methyltyrosines; Mice; Parasympathetic Nervous System; Picrotoxin; Semicarbazides; Stereotyped Behavior; Synaptic Transmission | 1978 |
Facilitation by GABA of the potassium-evoked release of 3-H-noradrenaline from the rat occipital cortex.
Topics: Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Muscimol; Nictitating Membrane; Norepinephrine; Picrotoxin; Potassium; Rats; Stimulation, Chemical; Synaptic Transmission; Tyramine | 1979 |
Delta-aminolaevulinic acid is a potent agonist for GABA autoreceptors.
Topics: Aminolevulinic Acid; Animals; Bicuculline; gamma-Aminobutyric Acid; Levulinic Acids; Male; Picrotoxin; Porphyrias; Potassium; Rats; Receptors, Neurotransmitter; Synaptosomes | 1979 |
The effects of intranigral injections of picrotoxin and carbachol in cats with a lesioned nigrostriatal pathway.
Topics: Animals; Atropine; Behavior, Animal; Carbachol; Cats; gamma-Aminobutyric Acid; Hydroxydopamines; Neural Pathways; Picrotoxin; Receptors, Cholinergic; Receptors, Neurotransmitter; Substantia Nigra | 1979 |
Behavioral and biochemical analysis of GABA-mediated inhibition in the early chick embryo.
Topics: 4-Aminobutyrate Transaminase; Age Factors; Aminobutyrates; Animals; Carboxy-Lyases; Chick Embryo; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Motor Activity; Muscimol; Neural Inhibition; Picrotoxin; Receptors, Neurotransmitter; Spinal Cord; Succinates; Transaminases | 1979 |
Presynaptic GABA autoreceptors on GABAergic nerve endings of the rat substantia nigra.
Topics: Animals; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Nerve Endings; Picrotoxin; Potassium; Rats; Receptors, Cell Surface; Substantia Nigra | 1979 |
Baclofen and cerebellar cyclic GMP levels in mice.
Topics: Animals; Arecoline; Baclofen; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Motor Activity; Pentylenetetrazole; Picrotoxin | 1979 |
[An analysis of the discrepancy between the effects of central and peripheral alpha-adrenoceptor stimulations (author's transl)].
Topics: Animals; Clonidine; gamma-Aminobutyric Acid; Hypotension; Picrotoxin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1979 |
Does picrotoxin interact with the 5-HT system in the flexor reflex?
Topics: Animals; Clonidine; Cyproheptadine; Drug Interactions; gamma-Aminobutyric Acid; Lysergic Acid Diethylamide; Male; Picrotoxin; Quipazine; Rats; Reflex, Stretch; Serotonin; Serotonin Antagonists; Synaptic Transmission | 1978 |
Anticonvulsant activity of muscimol against seizures induced by impairment of GABA-mediated neurotransmission.
Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Strychnine; Synaptic Transmission | 1979 |
Chemically induced chorieform activity: antagonism by GABA and EEG patterns.
Topics: Allyl Compounds; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carbachol; Cats; Caudate Nucleus; Cerebral Cortex; Chorea; Corpus Striatum; Drug Antagonism; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Glycine; Homocysteine; Male; Neostigmine; Nicotine; Physostigmine; Picrotoxin; Rats; Tubocurarine | 1975 |
Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam.
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Cerebellum; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoniazid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Strychnine | 1975 |
Tonic release of transmitter at the neuromuscular junction of the crab.
Topics: Animals; Brachyura; Calcium; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Neural Inhibition; Neuromuscular Junction; Neurotransmitter Agents; Picrotoxin; Synapses; Temperature | 1975 |
Evidence for GABA involvement in the action of diazepam on presynaptic nerve terminals in bullfrog sympathetic ganglia.
Topics: Action Potentials; Aminobutyrates; Animals; Anura; Cyclic AMP; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Ganglionic Blockers; Glutamates; Glycine; In Vitro Techniques; Nerve Endings; Picrotoxin; Rana catesbeiana | 1975 |
A comparison of the effects of GABA, 3-aminopropanesulphonic acid and imidazoleacetic acid on the frog spinal cord.
Topics: Aminobutyrates; Animals; Anura; Drug Interactions; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Kinetics; Picrotoxin; Rana esculenta; Sodium; Spinal Cord; Taurine; Tetrodotoxin; Time Factors | 1978 |
GABA, picrotoxin and retinal sensitivity.
Topics: Action Potentials; Aminobutyrates; Animals; Anura; Dark Adaptation; Electroretinography; gamma-Aminobutyric Acid; Picrotoxin; Rana pipiens; Retina | 1978 |
Effect of diazepam on cerebral 5-hydroxytryptamine synthesis.
Topics: 5-Hydroxytryptophan; Aminooxyacetic Acid; Animals; Bicuculline; Brain; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Reserpine; Serotonin | 1979 |
Effects of alterations in the metabolism of gamma-aminobutyrate on convulsant potencies.
Topics: 3-Mercaptopropionic Acid; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Diacetyl; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Hydrazines; Male; Mice; Pentylenetetrazole; Phenelzine; Picrotoxin; Pyridoxine; Reaction Time; Seizures; Thiones; Valproic Acid | 1977 |
Involvement of central GABA-ergic systems in convulsions and aggressive behavior.
Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Bicuculline; Brain; Fatty Acids; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Muscimol; Picrotoxin; Rats; Seizures; Structure-Activity Relationship; Valproic Acid | 1979 |
[Implication of GABA in the spatial organization of the receptive fields of retinal ganglia cells of frogs].
Topics: Aminobutyrates; Animals; Anura; Autoradiography; Binding Sites; Chickens; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Neural Inhibition; Picrotoxin; Rana temporaria; Retina; Visual Fields; Visual Pathways; Visual Perception | 1977 |
[Behavior modifications induced by unilateral administration of picrotoxin into rat substantia nigra].
Topics: Animals; Behavior, Animal; gamma-Aminobutyric Acid; Haloperidol; Humans; Male; Picrotoxin; Pimozide; Rats; Rotation; Stereotyped Behavior; Substantia Nigra | 1977 |
Neuroactive properties of phosphonic amino acids.
Topics: Amino Acids; Animals; Bicuculline; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Phosphorylation; Picrotoxin; Rats | 1979 |
Enhancement of the binding of 3H-diazepam to rat brain membranes in vitro by SQ 20009, A novel anxiolytic, gamma-aminobutyric acid (GABA) and muscimol.
Topics: Animals; Bicuculline; Brain; Diazepam; Etazolate; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Muscimol; Nicotinic Acids; Oxazoles; Picrotoxin; Rats; Stimulation, Chemical | 1979 |
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines.
Topics: Animals; Benzodiazepines; Bicuculline; Cats; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Pentobarbital; Picrotoxin | 1979 |
Effect of diazepam on GABAergic cuneate neurons.
Topics: Animals; Bicuculline; Cats; Diazepam; gamma-Aminobutyric Acid; Glutamates; Medulla Oblongata; Neurons; Picrotoxin | 1979 |
Sensitivity of cholinergic neurons to GABAergic and serotoninergic drugs in the rat striatum.
Topics: Acetylcholine; Animals; Cholinergic Fibers; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Picrotoxin; Quipazine; Rats; Serotonin | 1979 |
GABA-induced locomotor activity in the rat, after bilateral injection into the ventral tegmental area.
Topics: Animals; Baclofen; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Injections; Male; Motor Activity; Picrotoxin; Rats; Tegmentum Mesencephali; Time Factors | 1979 |
Turning behaviour induced by injection of muscimol or picrotoxin into the substantia nigra demonstrates dual GABA components.
Topics: Animals; gamma-Aminobutyric Acid; Male; Movement; Muscimol; Organ Specificity; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1979 |
Enhanced suppressive effects of aversive events induced in rats by picrotoxin: possibility of a GABA control of behavioral inhibition.
Topics: Animals; Avoidance Learning; Behavior, Animal; Drinking Behavior; gamma-Aminobutyric Acid; Male; Picrotoxin; Punishment; Rats; Reinforcement Schedule; Time Factors | 1979 |
Dual gamma-aminobutyric acid control of prolactin secretion in the rat.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Methyltyrosines; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats | 1979 |
Independent inhibition of prolactin secretion by dopamine and gamma-aminobutyric acid in vitro.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Flupenthixol; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Male; Picrotoxin; Pituitary Gland; Prolactin; Rats; Tissue Extracts | 1979 |
Blocking by picrotoxin of nigra-evoked inhibition of neurons of ventromedial nucleus of the thalamus.
Topics: Action Potentials; Animals; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Neural Inhibition; Neural Pathways; Picrotoxin; Substantia Nigra; Thalamic Nuclei | 1979 |
GABA modulates the release of dopamine and acetylcholine from rat caudate nucleus slices.
Topics: Acetylcholine; Animals; Bicuculline; Caudate Nucleus; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Norepinephrine; Picrotoxin; Potassium; Rats; Tyrosine | 1979 |
Conductance changes during bath application of beta-alanine and taurine in giant interneurons of the isolated lamprey spinal cord.
Topics: Alanine; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Electrolytes; gamma-Aminobutyric Acid; Glycine; Interneurons; Lampreys; Membrane Potentials; Picrotoxin; Spinal Cord; Strychnine; Taurine | 1979 |
Symmetric bilateral changes in dopamine release from the caudate nuclei of the cat induced by unilateral nigral application of glycine and GABA-related compounds.
Topics: Animals; Cats; Caudate Nucleus; Diazepam; Dominance, Cerebral; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Pathways; Picrotoxin; Potassium; Strychnine; Substantia Nigra; Tyrosine | 1979 |
Transient apnoea after systemic injection of GABA in the rat.
Topics: Animals; Apnea; Crotonates; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Respiration | 1979 |
Reduction of gamma-aminobutyric acid (GABA)-mediated transmission by a convulsant benzodiazepine.
Topics: Animals; Benzodiazepinones; Bicuculline; Cats; Convulsants; Female; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pentylenetetrazole; Picrotoxin; Reflex; Spinal Cord; Strychnine | 1979 |
Stoichiometry of GABA-receptor interactions: GABA modulates the glycine-receptor interaction allosterically in a vertebrate neuron.
Topics: Allosteric Regulation; Animals; Electric Conductivity; gamma-Aminobutyric Acid; Glycine; Grasshoppers; Kinetics; Mathematics; Muscles; Neurons; Picrotoxin; Receptors, Drug; Thermodynamics | 1979 |
Funneling mechanism in hearing.
Topics: Animals; Cats; Cochlea; gamma-Aminobutyric Acid; Hearing; Picrotoxin | 1979 |
Hypersynchronisation and sedation produced by GABA-transaminase inhibitors and picrotoxin: does GABA participate in sleep control?
Topics: 4-Aminobutyrate Transaminase; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Seizures; Sleep Stages; Transaminases | 1979 |
Role of dopaminergic and GABA-ergic interactions in seizure susceptibility.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Dopamine; Electroshock; Female; gamma-Aminobutyric Acid; Haloperidol; Male; Mice; Picrotoxin; Piribedil; Reserpine; Seizures | 1979 |
Effects of picrotoxin, naloxone, and vagotomy on chlordiazepoxide-induced respiratory depression.
Topics: Animals; Blood Pressure; Cats; Chlordiazepoxide; Depression, Chemical; Female; gamma-Aminobutyric Acid; Naloxone; Picrotoxin; Rats; Respiration; Species Specificity; Vagotomy | 1979 |
The GABA dose/conductance relationship on lobster muscle.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Guanidines; In Vitro Techniques; Muscles; Nephropidae; Picrotoxin; Piperazines; Propionates; Valerates | 1979 |
Rotational behaviour after unilateral intranigral injection of muscimol in rats.
Topics: Aminobutyrates; Animals; Basidiomycota; Behavior; Bicuculline; gamma-Aminobutyric Acid; Humans; Injections; Isoxazoles; Male; Oxazoles; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra; Time Factors | 1977 |
Specific antagonism of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of convulsant action.
Topics: Amino Acids; Aminobutyrates; Animals; Bicuculline; Convulsants; Culture Techniques; gamma-Aminobutyric Acid; Iontophoresis; Mice; Neural Inhibition; Neurons; Penicillins; Pentylenetetrazole; Picrotoxin; Spinal Cord | 1978 |
The striatal dopaminergic function is mediated by the inhibition of a nigral, non-dopaminergic neuronal system via a strio-nigral GABAergic pathway.
Topics: Aminobutyrates; Animals; Catalepsy; Corpus Striatum; Dopamine; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Neural Inhibition; Neural Pathways; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra | 1978 |
Contralateral turning evoked by the intranigral microinjection of muscimol and other GABA agonists.
Topics: Animals; Behavior; Caudate Nucleus; Dopamine Antagonists; Dose-Response Relationship, Drug; Ethanolamines; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Imidazoles; Muscimol; Oxazoles; Picrotoxin; Putamen; Rats; Stereotyped Behavior; Substantia Nigra | 1978 |
Evidence that nigral GABA mediates behavioural responses elicited by striatal dopamine receptor stimulation.
Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; Catatonia; Corpus Striatum; Drug Interactions; gamma-Aminobutyric Acid; Humans; Hydroxydopamines; Injections; Male; Picrotoxin; Rats; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra | 1978 |
Substantia nigra as an out-put station for striatal dopaminergic responses: role of a GABA-mediated inhibition of pars reticulata neurons.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Hydroxydopamines; Kainic Acid; Male; Neurons; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra | 1979 |
[Pathogenesis of stereotyped behavior].
Topics: Animals; Behavior; Caudate Nucleus; Diazepam; Disease Models, Animal; gamma-Aminobutyric Acid; Haloperidol; Humans; Lithium; Penicillins; Picrotoxin; Rats; Schizophrenia; Stereotyped Behavior; Syndrome; Tetanus Toxin | 1979 |
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Humans; Isoxazoles; Male; Methyltyrosines; Morphine; Motor Activity; Muscimol; Picrotoxin; Rats; Reserpine | 1979 |
Ketamine-induced rotation: interaction with GABA-transaminase inhibitors and picrotoxin.
Topics: 4-Aminobutyrate Transaminase; Anesthesia; Animals; Behavior; Drug Interactions; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Picrotoxin; Rats; Stereotyped Behavior; Transaminases | 1979 |
Presynaptic modulating effects of GABA on depression, facilitation, and posttetanic potentiation of a cholinergic synapse in Aplysia californica.
Topics: Acetylcholine; Aminobutyrates; Animals; Aplysia; Azides; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Lithium; Membrane Potentials; Picrotoxin; Potassium; Sodium; Synapses | 1977 |
Possible involvement of GABA mechanisms in central cardiovascular and respiratory control. Studies on the interaction between diazepam, picrotoxin and clonidine.
Topics: Aminobutyrates; Animals; Blood Pressure; Clonidine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Heart Rate; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Male; Picrotoxin; Rats; Respiration | 1977 |
Stimulation of dopamine release by GABA in rat striatal slices.
Topics: Aminobutyrates; Animals; Calcium; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Neurosecretion; Picrotoxin; Rats; Receptors, Dopamine; Tetrodotoxin; Tritium; Tyrosine | 1978 |
Effects of drugs on gamma-aminobutyric acid receptors, uptake, release and synthesis in vitro.
Topics: Aminobutyrates; Animals; Astacoidea; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Imipramine; In Vitro Techniques; Male; Mice; Penicillin G; Pentylenetetrazole; Picrotoxin; Receptors, Drug; Synaptosomes | 1978 |
Muscimol, GABA and picrotoxin: effects on membrane conductance of a crustacean neuron.
Topics: Aminobutyrates; Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Mechanoreceptors; Membrane Potentials; Mycotoxins; Neural Inhibition; Neurons; Oxazoles; Picrotoxin; Receptors, Drug; Synaptic Membranes | 1978 |
Characterization and ionic basis of GABA-induced depolarizations recorded in vitro from cat primary afferent neurones.
Topics: Aminobutyrates; Animals; Anions; Bicuculline; Cats; Cell Membrane Permeability; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons, Afferent; Picrotoxin; Receptors, Drug | 1978 |
The effects of intraventricularly administered GABA and picrotoxin and their interactions on somato-vegetative reflexes in cats.
Topics: Aminobutyrates; Animals; Blood Pressure; Cats; Drug Interactions; gamma-Aminobutyric Acid; Infusions, Parenteral; Injections, Intraventricular; Muscle Contraction; Muscle, Smooth; Nictitating Membrane; Picrotoxin; Reflex | 1978 |
Focal contralateral myoclonus produced by inhibition of GABA action in the caudate nucleus of rats.
Topics: Aminobutyrates; Animals; Carnitine; Caudate Nucleus; Corpus Striatum; Electrophysiology; Female; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Motor Activity; Motor Cortex; Myoclonus; Picrotoxin; Rats; Stimulation, Chemical | 1978 |
Gabaergic processes involved in the control of dopamine release from nigrostriatal dopaminergic neurons in the cat.
Topics: Aminobutyrates; Animals; Cats; Caudate Nucleus; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Male; Neurons; Picrotoxin; Substantia Nigra | 1978 |
The "mixed" effect of picrotoxin on the GABA dose/conductance relation recorded from lobster muscle.
Topics: Aminobutyrates; Animals; Bicuculline; Binding, Competitive; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Models, Biological; Nephropidae; Neural Conduction; Picrotoxin | 1978 |
Post-mortem and aminooxyacetic acid-induced accumulation of GABA: effect of gamma-butyrolactone and picrotoxin.
Topics: 4-Butyrolactone; Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Chloral Hydrate; Furans; gamma-Aminobutyric Acid; Male; Organ Specificity; Picrotoxin; Postmortem Changes; Rats | 1978 |
Motor activity of rats following intracerebral injections of drugs influencing GABA mechanisms.
Topics: Aminobutyrates; Animals; Apomorphine; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Hydroxybutyrates; Injections; Male; Motor Activity; Nucleus Accumbens; Pentylenetetrazole; Picrotoxin; Rats; Reserpine; Strychnine | 1978 |
[Effect of neuroactivating amino acids on the system activating sympathetic preganglionic neurons].
Topics: Aminobutyrates; Animals; Autonomic Fibers, Preganglionic; Cats; gamma-Aminobutyric Acid; Glutamates; Glycine; Interneurons; Muscles; Neurons, Afferent; Picrotoxin; Reaction Time; Reflex; Spinal Cord; Strychnine; Sympathetic Nervous System; Vasomotor System | 1978 |
A comparison of similar ionic responses to gamma-aminobutyric acid and acetylcholine.
Topics: Acetylcholine; Aminobutyrates; Animals; Aplysia; Bicuculline; Bungarotoxins; Cell Membrane Permeability; Chlorides; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Neurons; Picrotoxin; Potassium; Receptors, Drug; Sodium; Strychnine; Time Factors | 1978 |
Plasma cortisol of conscious cats during cerebroventricular perfusion with adrenergic, cholinergic and gabanergic antagonists.
Topics: Animals; Atropine; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Dexamethasone; Female; gamma-Aminobutyric Acid; Hydrocortisone; Male; Mecamylamine; Parasympatholytics; Phentolamine; Picrotoxin; Propranolol; Sympatholytics | 1978 |
Conductance increases produced by glycine and gamma-aminobutyric acid in lamprey interneurones.
Topics: Action Potentials; Aminobutyrates; Animals; Bicuculline; Chlorides; Electric Conductivity; Fishes; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Interneurons; Lampreys; Picrotoxin; Spinal Cord; Strychnine | 1978 |
Response of dopamine neurons in substantia nigra to muscimol.
Topics: Animals; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1978 |
The effects of elevating gamma-amino butyrate content in the substantia nigra on the behaviour of rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Apomorphine; Behavior, Animal; Cyclohexanecarboxylic Acids; Cyclohexylamines; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Male; Picrotoxin; Rats; Substantia Nigra; Time Factors | 1978 |
The role of GABA in the substantia nigra.
Topics: Amino Acids; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dopamine; gamma-Aminobutyric Acid; Male; Movement; Neural Pathways; Picrotoxin; Rats; Substantia Nigra | 1978 |
[Effects of imidazole, papaverine and theophylline on the picrotoxin convulsion-seizure threshold. The correlation with gamma-aminobutyric acid (GABA) and diazepam].
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; gamma-Aminobutyric Acid; Imidazoles; Male; Mice; Papaverine; Picrotoxin; Seizures; Theophylline; Time Factors | 1978 |
Effects of GABA on neuronal activities in the distal retina of the carp.
Topics: Animals; Carps; Color Perception; Cyprinidae; Electric Stimulation; Evoked Potentials; Feedback; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; Photic Stimulation; Photoreceptor Cells; Picrotoxin; Retina; Synapses | 1978 |
Augmentation by chlordiazepoxide of the inhibitory effects of taurine, beta-alanine and gamma-aminobutyric acid on spike discharges in guinea-pig cerebellar slices.
Topics: Action Potentials; Alanine; Animals; Cerebellum; Chlordiazepoxide; Convulsants; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Picrotoxin; Strychnine; Taurine | 1979 |
gamma-Aminobutyric acid-stimulated chloride permeability in crayfish muscle.
Topics: Aminobutyrates; Animals; Astacoidea; Biological Transport; Chlorides; gamma-Aminobutyric Acid; Kinetics; Muscles; Permeability; Picrotoxin; Structure-Activity Relationship | 1977 |
Na+-independent binding of GABA to the triton X-100 treated synaptic membranes from cerebellum of rat brain.
Topics: Aminobutyrates; Animals; Bicuculline; Binding Sites; Cerebellum; gamma-Aminobutyric Acid; Imidazoles; Kinetics; Male; Picrotoxin; Polyethylene Glycols; Rats; Sodium; Synaptic Membranes; Tubocurarine | 1977 |
Effects of gabaculine, a new potent inhibitor of gamma-amonobutyrate transaminase, on the brain gamma-amonobutyrate content and convulsions in mice.
Topics: 4-Aminobutyrate Transaminase; Aminobutyrates; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Cyclohexanes; Cyclohexylamines; Dose-Response Relationship, Drug; Electroshock; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Picrotoxin; Semicarbazides; Time Factors; Transaminases | 1977 |
Possible role of GABA in the development of tolerance to alcohol.
Topics: Aminobutyrates; Animals; Cerebellum; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Glucose; Kinetics; Male; Picrotoxin; Rats; Reflex | 1977 |
Effect of GABA, picrotoxin and bicuculline on loss of noradrenaline and serotonin from rat brain mesodiencephalic region in vitro.
Topics: Aminobutyrates; Animals; Bicuculline; Brain; Diencephalon; Female; gamma-Aminobutyric Acid; Isoquinolines; Male; Mesencephalon; Norepinephrine; Picrotoxin; Rats; Receptors, Drug; Serotonin | 1977 |
Evidence for an intrastriatal GABA-ergic influence on dopamine neurones of the cat.
Topics: Acetylcholinesterase; Aminobutyrates; Animals; Bicuculline; Brain; Cats; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Receptors, Dopamine | 1977 |
Effects of peripheral and local administration of picrotoxin on the release of newly synthesized 3H-dopamine in the caudate nucleus of the cat.
Topics: Animals; Cats; Caudate Nucleus; Dopamine; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Substantia Nigra | 1977 |
Amacrine cells in Necturus retina: evidence for independent gamma-aminobutyric acid- and glycine-releasing neurons.
Topics: Aminobutyrates; Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia; Glycine; In Vitro Techniques; Neural Inhibition; Neurons; Photic Stimulation; Picrotoxin; Retina; Strychnine; Urodela | 1977 |
Inhibition and excitation induced by glutamic acid on cerebellar interneurons.
Topics: Action Potentials; Animals; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Guinea Pigs; In Vitro Techniques; Interneurons; Neural Inhibition; Picrotoxin; Strychnine | 1977 |
Dopaminergic neurons: effects elicited by gamma-hydroxybutyrate are reversed by picrotoxin.
Topics: Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Neurons; Olfactory Bulb; Picrotoxin; Rats | 1977 |
The role of GABA in dyskinesias induced by chemical stimulation of the striatum.
Topics: Aminobutyrates; Animals; Bicuculline; Corpus Striatum; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats | 1977 |
Increase in striatal acetylcholine by picrotoxin in the rat: evidence for a gabergic-dopaminergic-cholinergic link.
Topics: Acetylcholine; Animals; Ascorbic Acid; Brain; Choline; Choline O-Acetyltransferase; Cholinesterases; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Hydroxydopamines; Methyltyrosines; Picrotoxin; Pimozide; Piribedil; Rats | 1976 |
Effects of GABA, glycine, picrotoxin and bicuculline methochloride on rubrospinal neurones in cats.
Topics: Aminobutyrates; Animals; Bicuculline; Cats; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Neural Inhibition; Neural Pathways; Picrotoxin; Red Nucleus; Spinal Cord; Synaptic Membranes | 1976 |
Action of amino acids and convulsants on cerebellar spontaneous action potentials in vitro: effects of deprivation of C1-, K+ of Na+.
Topics: Action Potentials; Alanine; Amino Acids; Animals; Bicuculline; Cerebellum; Chlorides; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; Iodides; Isethionic Acid; Nitrates; Picrotoxin; Potassium; Sodium; Strychnine; Sulfates | 1976 |
Retention disruption following post-trial picrotoxin injection into the substantia nigra.
Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Memory; Picrotoxin; Rats; Reaction Time; Retention, Psychology; Seizures; Strychnine; Substantia Nigra | 1976 |
The behavioural effects of manipulating GABA function in the globus pallidus.
Topics: Aminobutyrates; Animals; Cerebellum; Cerebral Cortex; Ethanolamines; Female; gamma-Aminobutyric Acid; Globus Pallidus; Glycine; Limbic System; Male; Motor Activity; Picrotoxin; Rats | 1976 |
Inhibitory effects of acetylcholine on neurones in the feline nucleus reticularis thalami.
Topics: Acetylcholine; Action Potentials; Animals; Bicuculline; Cats; Depression, Chemical; Female; gamma-Aminobutyric Acid; Glycine; Male; Neurons; Picrotoxin; Receptors, Cholinergic; Strychnine; Thalamic Nuclei | 1976 |
Gamma-aminobutyric acid: selective inhibition of electrically induced head-turning following intracaudate administration.
Topics: Aminobutyrates; Animals; Basal Ganglia; Behavior; Caudate Nucleus; Electric Stimulation; gamma-Aminobutyric Acid; Humans; Injections; Male; Picrotoxin; Rats; Stereotyped Behavior; Time Factors | 1976 |
Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Humans; Hyperkinesis; Male; Norepinephrine; Picrotoxin; Rats; Serotonin; Syndrome; Tranylcypromine; Tryptophan | 1976 |
Picrotoxin convulsions and GABA metabolism after injection of anticonvulsants in chicks.
Topics: 4-Aminobutyrate Transaminase; Aminobutyrates; Animals; Anticonvulsants; Brain Chemistry; Chickens; Diazepam; gamma-Aminobutyric Acid; Phenobarbital; Picrotoxin | 1976 |
The action of taurine on the lobster muscle fibre an d the frog spinal cord.
Topics: Animals; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Nephropidae; Neural Conduction; Picrotoxin; Receptors, Drug; Spinal Cord; Taurine; Tetrodotoxin | 1976 |
Electrophysiological studies of fetal mouse olifactory bulb explants during development of synaptic functions in culture.
Topics: Action Potentials; Animals; Bicuculline; Caffeine; Evoked Potentials; Fetus; gamma-Aminobutyric Acid; Mice; Neural Inhibition; Neurons; Olfactory Bulb; Organ Culture Techniques; Picrotoxin; Synapses; Time Factors; Tubocurarine | 1976 |
Antagonism of diazepam against central anticholinergic drug-induced hyperactivity in mice: involvement of a GABA mechanism.
Topics: Aminobutyrates; Animals; Atropine; Benztropine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Motor Activity; Parasympatholytics; Picrotoxin; Scopolamine; Semicarbazides; Strychnine; Trihexyphenidyl | 1976 |
[Participation of GABA and glycine in the formation of somato-sympathetic reflexes].
Topics: Aminobutyrates; Animals; Cats; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Picrotoxin; Reflex; Spinal Cord; Strychnine; Sympathetic Nervous System | 1976 |
[A pharmacologic analysis of the slow potential arising in response to adequate stimulation of the frog olfactory bulb].
Topics: Animals; Anura; Chloralose; gamma-Aminobutyric Acid; Membrane Potentials; Morphine; Olfactory Bulb; Penicillins; Pentobarbital; Picrotoxin; Rana temporaria; Strychnine | 1975 |
A comparative study of the action of gamma-aminobutyric acid and piperazine on the lobster muscle fibre and the frog spinal cord.
Topics: Aminobutyrates; Animals; Chlorides; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Nephropidae; Picrotoxin; Piperazines; Rana temporaria; Spinal Cord; Tetrodotoxin | 1976 |
Enhancement of picrotoxin convulsions in chicks and mice by the prior intraperitoneal injection of hypertonic GABA or mannitol.
Topics: Aminobutyrates; Animals; Animals, Newborn; Chickens; Drug Synergism; gamma-Aminobutyric Acid; Hypertonic Solutions; Injections, Intraperitoneal; Mannitol; Mice; Mice, Inbred Strains; Picrotoxin; Seizures; Time Factors | 1975 |
The effects of various amino acids, dopamine and some convulsants on the electroretinogram of the rabbit.
Topics: Alanine; Amino Acids; Animals; Bicuculline; Convulsants; Dopamine; Electroretinography; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Male; Picrotoxin; Rabbits; Retina; Strychnine; Taurine | 1975 |
Focal myoclonus produced by injection of picrotoxin into the caudate nucleus of the rat.
Topics: Animals; Caudate Nucleus; gamma-Aminobutyric Acid; Myoclonus; Picrotoxin; Rats | 1975 |
Characterization of an inhibitory receptor in rat hippocampus: a microiontophoretic study using conformationally restricted amino acid analogues.
Topics: Amino Acids; Animals; Cyclohexanes; Cyclopentanes; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Male; Picrotoxin; Rats; Receptors, Drug | 1975 |
The anticonvulsant action of GABA-elevating agents: a re-evaluation.
Topics: Allyl Compounds; Aminobutyrates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hydrazines; Hydroxylamines; Hyperbaric Oxygenation; Isoniazid; Male; Mice; Pentylenetetrazole; Picrotoxin; Seizures; Stimulation, Chemical; Time Factors | 1975 |
The effect of intravenously administered gamma-aminobutyric acid on afferent fiber polarization.
Topics: Aminobutyrates; Animals; Bicuculline; Cats; Decerebrate State; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Injections, Intra-Arterial; Injections, Intravenous; Lumbar Vertebrae; Membrane Potentials; Neurons; Neurons, Afferent; Phenoxybenzamine; Picrotoxin; Tetrodotoxin | 1975 |
Pentobarbital: action on frog motoneurons.
Topics: Animals; Anura; Aspartic Acid; Bicuculline; Cell Membrane Permeability; Depression, Chemical; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Motor Neurons; Pentobarbital; Picrotoxin | 1975 |
Binding of gamma-aminobutyric acid to crayfish muscle and its relationship to receptor sites.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Astacoidea; Bicuculline; Binding Sites; Chlorpromazine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Mercaptoethanol; Muscle Proteins; Muscles; Picrotoxin; Protein Binding | 1975 |
Locomotor activity and seizures induced by picrotoxin in the fastigeal nucleus of the rat.
Topics: Animals; Cerebellar Nuclei; gamma-Aminobutyric Acid; Locomotion; Male; Neural Inhibition; Ouabain; Picrotoxin; Rats; Seizures | 1975 |
The effects of GABA, Picrotoxin and bicuculline on the spontaneous bioelectric activity of cultured cerebellar Purkinje cells.
Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Depression, Chemical; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Isoquinolines; Picrotoxin; Purkinje Cells; Rats; Stimulation, Chemical; Strychnine | 1975 |
The action of picrotoxin and bicuculline on rat caudate neurons inhibited by GABA.
Topics: Aminobutyrates; Animals; Bicuculline; Caudate Nucleus; Cerebral Cortex; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Isoquinolines; Male; Picrotoxin; Rats | 1976 |
Reduction of gamma-aminobutyric acid level in the cat cerebral cortex by afferent electrical stimulation.
Topics: Aminobutyrates; Animals; Brachial Plexus; Cats; Cerebral Cortex; Electric Stimulation; Female; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Picrotoxin | 1976 |
Analysis of amino acid responses on frog motoneurones.
Topics: Alanine; Amino Acids; Animals; Chlorides; gamma-Aminobutyric Acid; Glutamates; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; Picrotoxin; Sodium; Strychnine; Taurine | 1976 |
Effects of GABA blockade on lateral hypothalamic self-stimulation.
Topics: Aminobutyrates; Animals; Bicuculline; gamma-Aminobutyric Acid; Hypothalamus; Male; Picrotoxin; Rats; Self Stimulation | 1976 |
Interleukin-2 inhibits the GABA-induced Cl- current in identified Aplysia neurons.
Topics: Animals; Aplysia; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Interleukin-2; Ion Channels; Membranes; Muscimol; Neurons; Picrotoxin; Recombinant Proteins; Seawater | 1992 |
gamma-Hydroxybutyric acid binding sites: interaction with the GABA-benzodiazepine-picrotoxin receptor complex.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Oxybate; Synaptic Membranes | 1992 |
Accumbens-caudate-septal circuit as a system for hippocampal regulation: involvement of a GABAergic neurotransmission.
Topics: Animals; Cats; Caudate Nucleus; Electric Stimulation; Electroencephalography; gamma-Aminobutyric Acid; Globus Pallidus; Hippocampus; Nucleus Accumbens; Penicillins; Picrotoxin; Synaptic Transmission | 1992 |
Pharmacological characterization of GABAB-mediated responses in the CA1 region of the rat hippocampal slice.
Topics: Animals; Baclofen; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Organophosphorus Compounds; Picrotoxin; Rats; Receptors, GABA-A | 1992 |
Inhibitory responses of rat basolateral amygdaloid neurons recorded in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amygdala; Animals; Baclofen; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Histocytochemistry; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Neurons; Picrotoxin; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereotyped Behavior | 1992 |
Granule cell inhibition and the activity of hilar neurons.
Topics: 4-Aminopyridine; Animals; Axons; Baclofen; Dendrites; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Neural Inhibition; Neural Pathways; Neurons; Picrotoxin; Potassium Channels; Receptors, GABA-A; Synapses | 1992 |
Participation of GABAergic systems in the production of antinociception by various stresses in mice.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Stress, Psychological | 1992 |
Postsynaptic action of endogenous GABA released by nipecotic acid in the hippocampus.
Topics: Animals; Carrier Proteins; Electrodes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Nipecotic Acids; Organophosphorus Compounds; Picrotoxin; Proline; Pyramidal Tracts; Rats; Synapses; Tetrodotoxin | 1992 |
Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum.
Topics: Animals; Ascaris suum; Bicuculline; Cholinergic Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ivermectin; Muscles; Organophosphorus Compounds; Parasympatholytics; Parasympathomimetics; Picrotoxin; Receptors, Cholinergic; Receptors, GABA-A | 1992 |
Differential action of (-)-baclofen on the primary afferent depolarization produced by segmental and descending inputs.
Topics: Anesthesia; Animals; Baclofen; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Interneurons; Nerve Fibers; Neuromuscular Depolarizing Agents; Neurons, Afferent; Picrotoxin; Receptors, GABA-A; Reticular Formation; Skin; Spinal Cord; Synapses | 1992 |
Gamma-aminobutyric acid-glutamate interaction in the control of somatostatin release from hypothalamic neurons in primary culture: in vivo corroboration.
Topics: Animals; Bicuculline; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Fetus; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypothalamus; Kinetics; Male; Median Eminence; Neurons; Picrotoxin; Pipecolic Acids; Rats; Rats, Inbred Strains; Reference Values; Somatostatin; Tetrodotoxin | 1992 |
Modulation of extracellular pH by glutamate and GABA in rat hippocampal slices.
Topics: Acetazolamide; Animals; Benzolamide; Carbonic Anhydrase Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Neurons, Afferent; Picrotoxin; Rats; Synapses | 1992 |
Inhibitory effects of beta-alanine on the vagal efferent and afferent excitatory responses of the stomach to stimulation of vagal trunk in cats.
Topics: Animals; beta-Alanine; Bicuculline; Cats; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glycine; Hexamethonium; Hexamethonium Compounds; Male; Neurons, Afferent; Neurons, Efferent; Picrotoxin; Stomach; Taurine; Vagus Nerve | 1992 |
GABA-mediated positive autofeedback loop controls horizontal cell kinetics in tiger salamander retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma; Animals; Carrier Proteins; Cell Membrane; Cyclic AMP; Evoked Potentials; Feedback; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Light; Mathematics; Membrane Proteins; Membrane Transport Proteins; Models, Biological; Nerve Tissue Proteins; Organic Anion Transporters; Photic Stimulation; Picrotoxin; Quinoxalines; Receptors, GABA-A; Retina | 1992 |
Dynamic observation of dopamine autoreceptor effects in rat striatal slices.
Topics: Acetylcholine; Animals; Atropine; Caudate Nucleus; Dopamine; Dopamine Agents; Electric Stimulation; Ergolines; gamma-Aminobutyric Acid; Glutamine; Homeostasis; Male; Picrotoxin; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synapses; Synaptic Transmission; Time Factors | 1992 |
The effects of gamma-aminobutyric acid on voltage-clamped motoneurons of the lobster cardiac ganglion.
Topics: Animals; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Ganglia; Membrane Potentials; Motor Neurons; Nephropidae; Nipecotic Acids; Picrotoxin; Proline; Receptors, GABA-A; Sodium | 1992 |
Receptive field properties of rod-driven horizontal cells in the skate retina.
Topics: Animals; Bicuculline; Dopamine; gamma-Aminobutyric Acid; Glycine; Intercellular Junctions; Isoquinolines; Light; Neurotransmitter Agents; Photoreceptor Cells; Picrotoxin; Retina; Skates, Fish | 1992 |
Chloride current induced by alcohols in rat dorsal root ganglion neurons.
Topics: Alcohols; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Picrotoxin; Rats; Structure-Activity Relationship | 1992 |
Neuropharmacology of amide derivatives of P-GABA.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Brain; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Muscle Relaxation; Nervous System; Picrotoxin; Seizures | 1992 |
Increased activity of the GABAergic system in selected brain areas after chronic propranolol treatment in spontaneously hypertensive rats.
Topics: Aminooxyacetic Acid; Animals; Blood Pressure; Dihydralazine; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred SHR | 1992 |
Barbiturates suppress glucose utilization by inhibition of hexokinase in neuroblastoma cells.
Topics: 3-O-Methylglucose; Barbiturates; Biological Transport; Cell Line; Deoxyglucose; gamma-Aminobutyric Acid; Hexokinase; Humans; Kinetics; Methylglucosides; Neuroblastoma; Pentobarbital; Picrotoxin; Tumor Cells, Cultured | 1992 |
Direct evidence for presynaptic inhibitory mechanisms in crayfish sensory afferents.
Topics: Animals; Astacoidea; Electrodes; Female; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Male; Microinjections; Motor Neurons; Nerve Endings; Neurons, Afferent; Picrotoxin; Reflex, Monosynaptic; Synapses | 1992 |
Tonic activity of rat medial vestibular nucleus neurones in vitro and its inhibition by GABA.
Topics: Action Potentials; Animals; Baclofen; Cobalt; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neurons; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Vestibular Nuclei | 1992 |
GABAA and GABAB receptor-mediated effects on the spontaneous activity of the longitudinal layer in cat terminal ileum.
Topics: Animals; Baclofen; Bicuculline; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1991 |
Depolarizing actions of GABA and glycine on amphibian retinal horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Cobalt; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kynurenine; Lithium; Neuromuscular Depolarizing Agents; Nicotinic Acids; Picrotoxin; Receptors, GABA-A; Retina; Urodela | 1991 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Muscimol; Pentobarbital; Phenobarbital; Phenotype; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Selection, Genetic | 1991 |
Ethanol interactions at the gamma-aminobutyric acid receptor complex.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Chlorides; Dizocilpine Maleate; Embryo, Mammalian; Ethanol; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1991 |
Induction of food intake by a GABAergic mechanism in the turkey.
Topics: Animals; Brain; Brain Mapping; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; gamma-Aminobutyric Acid; Muscimol; Paraventricular Hypothalamic Nucleus; Picrotoxin; Receptors, GABA-A; Substantia Nigra; Turkeys; Ventromedial Hypothalamic Nucleus | 1991 |
Can Cl- ions be extruded from a gamma-aminobutyric (GABA)-acceptive nerve cell via GABAA receptors on the plasma membrane cytoplasmic side?
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; Cytoplasm; gamma-Aminobutyric Acid; Membrane Potentials; Models, Biological; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A; Vestibular Nucleus, Lateral | 1991 |
Inhibition of calcium influx and calcium current by gamma-aminobutyric acid in single synaptic terminals.
Topics: Animals; Baclofen; Calcium; Calcium Channels; Electric Conductivity; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Retina; Synapses | 1991 |
Benzodiazepine receptor ligands and sexual behavior in the male rat: the role of GABAergic mechanisms.
Topics: Animals; Bicuculline; Carbolines; Chlordiazepoxide; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal | 1991 |
Role of dopamine and GABA in the control of motor activity elicited from the rat nucleus accumbens.
Topics: Animals; Baclofen; Dopamine; Dopamine Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Motor Activity; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Sesterterpenes; Taurine | 1991 |
Effects of GABA and related agents on the electrical activity of hypothalamic ventromedial nucleus neurons in vitro.
Topics: Animals; Baclofen; Bicuculline; Electrophysiology; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Ventromedial Hypothalamic Nucleus | 1991 |
Avian locomotion activated by brainstem infusion of neurotransmitter agonists and antagonists. II. gamma-Aminobutyric acid.
Topics: Animals; Brain Stem; Ducks; Electric Stimulation; gamma-Aminobutyric Acid; Geese; Motor Activity; Muscimol; Picrotoxin; Receptors, GABA-A; Reticular Formation | 1991 |
The effects of pentobarbital and benzodiazepines on GABA-responses in the periphery and spinal cord in vitro.
Topics: Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Male; Pentobarbital; Peripheral Nerves; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synapses; Vagus Nerve | 1991 |
GABAergic drugs and conflict behavior in the rat: lack of similarities with the actions of benzodiazepines.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Behavior, Animal; Benzodiazepines; Bicuculline; Brain; Conflict, Psychological; Drug Interactions; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Nicotinic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1991 |
Cyclic AMP induces long-term increase in synaptic efficacy in CA1 region of rat hippocampus.
Topics: Animals; Bucladesine; Cyclic AMP; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Picrotoxin; Pyramidal Tracts; Rats; Receptors, Purinergic; Stimulation, Chemical; Synapses; Synaptic Transmission | 1991 |
Modulation of GABA-mediated inhibition in rat cerebellar slices by benzodiazepine receptor ligands.
Topics: Animals; Bicuculline; Cerebellum; Electric Stimulation; Electrodes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Male; Picrotoxin; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
gamma-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex.
Topics: Amino Acids; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Culture Media; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Nerve Endings; Nipecotic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Somatostatin; Synaptosomes | 1991 |
Glutamate and GABA-mediated synaptic currents in neurons of the rat dorsal motor nucleus of the vagus.
Topics: Action Potentials; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Strychnine; Synapses; Tetrodotoxin; Vagus Nerve | 1991 |
Dorsal root potentials in the isolated frog spinal cord: amino acid neurotransmitters and magnesium ions.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kynurenic Acid; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Potassium Channels; Quinoxalines; Rana pipiens; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots; Synaptic Transmission | 1991 |
GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Synchronized GABAergic IPSPs recorded in the neocortex after blockade of synaptic transmission mediated by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Picrotoxin; Quinoxalines; Synapses; Synaptic Transmission | 1991 |
Interaction of hypothalamic GABAA and excitatory amino acid receptors controlling heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kynurenic Acid; Male; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
NMDA receptors participate differentially in two different synaptic inputs in neurons of the zebra finch robust nucleus of the archistriatum in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Birds; Brain; Electric Stimulation; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Picrotoxin; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Vocalization, Animal | 1991 |
Involvement of GABAergic systems in benzodiazepine-induced impairment of passive avoidance learning in mice.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; Chlordiazepoxide; Drug Interactions; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin | 1991 |
Glycinergic control of [Leu5]enkephalin levels in chicken retina.
Topics: Animals; Baclofen; Chickens; Enkephalin, Leucine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Muscimol; Neurotransmitter Agents; Picrotoxin; Radioimmunoassay; Retina; Strychnine | 1991 |
Gamma-aminobutyric acid (GABAB) receptor-mediated inhibition of tyrosine hydroxylase activity in the striatum of rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Calcium; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Hydrazines; In Vitro Techniques; Male; Muscimol; Neural Pathways; Picrotoxin; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
Effects of dihydroavermectin B1a and analogs on stretcher muscle of the lined shore crab, Pachygrapsus crassipes.
Topics: Animals; Anthelmintics; Bicuculline; Brachyura; Caenorhabditis; Chlorides; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Membrane Potentials; Membranes; Motor Endplate; Muscimol; Muscles; Picrotoxin; Sesterterpenes; Structure-Activity Relationship; Synapses; Time Factors | 1991 |
Prolonged exposure to GABA activates GABA-gated chloride channels in the presence of channel-blocking convulsants.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Convulsants; Endrin; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sesterterpenes; Xenopus | 1991 |
Action of taurine, 3-aminopropanesulfonic acid, and GABA on the hindgut and heart of the cockroach, Leucophaea maderae.
Topics: Amino Acids; Animals; Bicuculline; Cockroaches; Digestive System; Digestive System Physiological Phenomena; gamma-Aminobutyric Acid; Heart; In Vitro Techniques; Neurotransmitter Agents; Organ Specificity; Picrotoxin; Taurine | 1991 |
Paradoxical role of GABA in a chronic model of petit mal (absence)-like epilepsy in the rat.
Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Epilepsy, Absence; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Seizures; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 1990 |
Effects of glycine and GABA on isolated bipolar cells of the mouse retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Mice; Neurons; Pentobarbital; Picrotoxin; Potassium; Retina; Sodium; Strychnine | 1990 |
GABAA receptor-mediated increase in membrane chloride conductance in rat paratracheal neurones.
Topics: Animals; Bicuculline; Cell Membrane; Chlorides; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin; Trachea | 1990 |
The effect of subunit composition of rat brain GABAA receptors on channel function.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Carbolines; Dactinomycin; Diazepam; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Xenopus | 1990 |
Pharmacological evidence indicating a role of GABAergic systems in termination of limbic seizures.
Topics: Animals; Baclofen; Bicuculline; Chloride Channels; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Limbic System; Male; Membrane Proteins; Muscimol; Neural Inhibition; Picrotoxin; Rats; Seizures | 1990 |
Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.
Topics: Animals; Baclofen; Bicuculline; Cattle; Cerebral Cortex; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression; Membrane Potentials; Oocytes; Pentobarbital; Picrotoxin; Poly A; Rats; Receptors, GABA-A; Retina; RNA; RNA, Messenger; Transfection; Xenopus | 1991 |
Effect of gamma-aminobutyric acid on intracellular pH in the crayfish stretch-receptor neurone.
Topics: Acetazolamide; Action Potentials; Animals; Astacoidea; Bicarbonates; Chlorides; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Ion Channels; Mechanoreceptors; Membrane Potentials; Microelectrodes; Picrotoxin; Synaptic Membranes | 1991 |
The effect of chronic alcoholism on neuroendocrine and immune parameters.
Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Analysis of Variance; Antigens, CD; Bromocriptine; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Haloperidol; Humans; Immune System; Immunoglobulin A; Immunoglobulin E; Immunoglobulin G; Immunoglobulin M; Immunophenotyping; Interferons; Middle Aged; Neurosecretory Systems; Picrotoxin; Prolactin | 1991 |
GABA-induced potentiation of neuronal excitability occurs during contiguous pairings with intracellular calcium elevation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brachyura; Calcium; Chloride Channels; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Isoquinolines; Kinetics; Membrane Potentials; Membrane Proteins; Neurons; Photoreceptor Cells; Picrotoxin; Piperazines; Protein Kinase C; Synapses; Time Factors | 1991 |
Possible mediation of GABA induced growth hormone secretion by increased calcium-flux in neonatal pituitaries.
Topics: Animals; Animals, Newborn; Calcium; Female; gamma-Aminobutyric Acid; Growth Hormone; Male; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Potassium; Rats; Thyrotropin-Releasing Hormone | 1992 |
Volatile anesthetics gate a chloride current in postnatal rat hippocampal neurons.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anesthetics; Animals; Animals, Newborn; Bicuculline; Chlorine; Chromatography, Gas; Culture Techniques; Dose-Response Relationship, Drug; Electrophysiology; Enflurane; gamma-Aminobutyric Acid; Halothane; Hippocampus; Ion Channel Gating; Isoflurane; Neurons; Picrotoxin; Rats; Sesterterpenes; Strychnine | 1992 |
Evidence that genetic differences in habituation and GABAergic mechanisms may be related to sensitivity to ethanol and development of ethanol tolerance in mice.
Topics: Animals; Avoidance Learning; Bicuculline; Body Temperature; Brain; Drug Tolerance; Environment; Ethanol; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Motor Activity; Picrotoxin; Postural Balance; Seizures; Sleep; Species Specificity | 1991 |
GABAergic and enkephalinergic regulation of locomotion in the ventral pallidum: involvement of the mesolimbic dopamine system.
Topics: Animals; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Globus Pallidus; Limbic System; Locomotion; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains | 1991 |
[Drug-induced seizures in taurine-deficient mice].
Topics: Amino Acids; Animals; Brain Chemistry; Female; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Picrotoxin; Seizures; Strychnine; Taurine | 1991 |
Action of gamma-aminobutyric acid (GABA) in the isolated photosensory pineal organ.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Kinetics; Light; Muscimol; Neurons; Photic Stimulation; Picrotoxin; Pineal Gland; Time Factors; Trout | 1991 |
M-wave of the toad electroretinogram.
Topics: Animals; Bufo marinus; Electroretinography; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Microelectrodes; Photic Stimulation; Picrotoxin; Potassium; Retina | 1991 |
t-[35S]butylbicyclophosphorothionate binding under equilibrium and nonequilibrium conditions: differential effects of barbiturates and gamma-aminobutyric acid in the long-sleep and short-sleep selected mouse lines.
Topics: Animals; Barbiturates; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Cerebral Cortex; Chloride Channels; Ethanol; gamma-Aminobutyric Acid; Kinetics; Male; Membrane Proteins; Mice; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Sleep | 1991 |
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Female; gamma-Aminobutyric Acid; Gene Library; Humans; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Oligonucleotide Probes; Oocytes; Organ Specificity; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA-A; Retina; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection; Xenopus | 1991 |
Evidence for inhibitory amino acid receptors on guinea pig medial vestibular nucleus neurons in vitro.
Topics: Animals; Brain Stem; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Neurons; Picrotoxin; Receptors, Amino Acid; Receptors, Cell Surface; Strychnine; Vestibular Nuclei | 1991 |
Decreased sensitivity of cerebellar nuclei neurons to GABA and taurine: effects of long-term inferior olive destruction in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Bicuculline; Cerebellar Nuclei; gamma-Aminobutyric Acid; Iontophoresis; Male; Neurons; Olivary Nucleus; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains; Reference Values; Strychnine; Taurine | 1991 |
Effects of gamma-aminobutyric acid and glycine on synaptic excitability of neurones in the solitary tract nucleus.
Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Medulla Oblongata; Neurons, Afferent; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Synapses | 1991 |
[The spontaneous synaptic activity in a cell culture of chick embryo spinal cord].
Topics: Animals; Cells, Cultured; Chick Embryo; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Neural Inhibition; Neurons; Picrotoxin; Spinal Cord; Strychnine; Synapses; Time Factors | 1991 |
Interaction between pressor and depressor areas in cat ventrolateral medulla.
Topics: Animals; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Kainic Acid; Male; Medulla Oblongata; Models, Neurological; Organ Specificity; Picrotoxin; Strychnine; Time Factors | 1991 |
Synthesis and anticonvulsant activity of some benzopyranone imino derivatives of GABA and related compounds.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Chromans; gamma-Aminobutyric Acid; Imines; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Pentylenetetrazole; Picrotoxin; Rats | 1991 |
Hypothalamic GABAergic modulation of respiratory responses to baroreceptor stimulation.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbon Dioxide; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Microinjections; Picrotoxin; Pressoreceptors; Rats; Rats, Inbred Strains; Respiration | 1991 |
Participation of the GABAergic system of the turtle retina in the light adaptation process.
Topics: Adaptation, Physiological; Animals; Electroretinography; gamma-Aminobutyric Acid; Interneurons; Membrane Potentials; Photic Stimulation; Photoreceptor Cells; Picrotoxin; Retina; Turtles | 1991 |
Inhibitory synaptic inputs to the respiratory rhythm generator in the medulla isolated from newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Respiration; Strychnine; Synapses | 1990 |
GABAergic control on the intensity-response function of ERG waves under different background illumination.
Topics: Animals; Electroretinography; gamma-Aminobutyric Acid; Picrotoxin; Rana ridibunda; Retina; Synaptic Transmission | 1990 |
[The participation of the GABA-A and GABA-B receptors in the mechanism of the inhibition of the contractile activity in the rabbit myometrium under the influence of GABA, AOAA and fenibut].
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rabbits; Receptors, GABA-A; Uterine Contraction | 1990 |
The effects of ablation of the visual cortical area on the formation of LTP in the superior colliculus of the rat.
Topics: Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Interneurons; Male; Optic Nerve; Picrotoxin; Rats; Rats, Inbred Strains; Superior Colliculi; Synaptic Transmission; Visual Cortex | 1990 |
Peripheral administration of picrotoxin and bicuculline stimulates in vivo somatostatin release from rat median eminence.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Median Eminence; Picrotoxin; Rats; Rats, Inbred Strains; Somatostatin | 1990 |
Posterior midbrain-induced locomotion.
Topics: Animals; Aspartic Acid; Bicuculline; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Mesencephalon; Muscles; N-Methylaspartate; Neurotransmitter Agents; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Axons; Dipeptides; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Neurotoxins; Nucleus Accumbens; Pentobarbital; Picrotoxin; Pyridostigmine Bromide; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Time Factors; Tubocurarine | 1990 |
Valproate potentiates and picrotoxin antagonizes the anxiolytic action of ethanol in a nonshock conflict task.
Topics: Animals; Anti-Anxiety Agents; Conflict, Psychological; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Picrotoxin; Rats; Rats, Inbred Strains; Valproic Acid | 1990 |
Cortisone: a potent GABAA antagonist in the guinea-pig isolated ileum.
Topics: Androstanes; Animals; Azasteroids; Cortisone; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Ileum; In Vitro Techniques; Male; Models, Molecular; Muscle Contraction; Muscle, Smooth; Picrotoxin; Sesterterpenes | 1990 |
GABA mediated inhibition of abdominal postural flexion in lobster.
Topics: Abdomen; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Interneurons; Muscimol; Nephropidae; Physical Stimulation; Picrotoxin; Posture; Reflex | 1991 |
gamma-Aminobutyric acid-induced response in acutely isolated nucleus solitarii neurons of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Penicillin G; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1991 |
GABA-related feeding control in genetically obese rats.
Topics: Animals; Deoxyglucose; Feeding Behavior; Female; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Hypothalamus; Muscimol; Obesity; Picrotoxin; Rats; Rats, Zucker; Stereotaxic Techniques; Ventromedial Hypothalamic Nucleus | 1991 |
Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA.
Topics: Analgesia; Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; N-Methylaspartate; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Receptors, Serotonin; Serotonin; Spinal Cord | 1991 |
[Observation on phrenic discharges induced by bicuculline or picrotoxin in spinal rabbits].
Topics: Animals; Bicuculline; Evoked Potentials; Female; gamma-Aminobutyric Acid; Male; Phrenic Nerve; Picrotoxin; Rabbits; Respiration; Spinal Cord | 1990 |
The role of serotonin release and autoreceptors in the dorsalis raphe nucleus in the control of serotonin release in the cat caudate nucleus.
Topics: Animals; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Kinetics; Male; Methiothepin; Phenethylamines; Picrotoxin; Raphe Nuclei; Serotonin; Tritium; Tryptophan | 1990 |
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Neurons; Pentylenetetrazole; Picrotoxin; Rats; Succinimides; Thalamus | 1990 |
Involvement of the nigral output pathways in the inhibitory control of the substantia nigra over generalized non-convulsive seizures in the rat.
Topics: Animals; Brain; Dopamine; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Muscimol; Norepinephrine; Oxidopamine; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Serotonin; Substantia Nigra | 1990 |
A functional interaction between GABA and 5-HT in inhibiting picrotoxin-induced myoclonus in rats.
Topics: 5-Hydroxytryptophan; Aminooxyacetic Acid; Animals; Fenclonine; gamma-Aminobutyric Acid; Male; Myoclonus; Picrotoxin; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Enhancement by GABA of the stimulation-evoked catecholamine release from cultured bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Glands; Animals; Bicuculline; Caffeine; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Nicotine; Picrotoxin; Potassium; Receptors, GABA-A; Veratridine | 1990 |
Electrophysiological evidence for the existence of GABAA receptors in cultured frog melanotrophs.
Topics: alpha-MSH; Animals; Cells, Cultured; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; Male; Membrane Potentials; Membrane Proteins; Picrotoxin; Pituitary Gland, Posterior; Rana ridibunda; Ranidae; Receptors, GABA-A | 1990 |
Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Brain; Cloning, Molecular; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Oocytes; Organ Specificity; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; RNA, Messenger; Xenopus laevis | 1990 |
Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus.
Topics: Action Potentials; Animals; Baclofen; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Picrotoxin; Rats; Synapses; Synaptic Transmission; Tetrodotoxin | 1990 |
Evidence for functionally distinct subclasses of gamma-aminobutyric acid receptors in rabbit retina.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Binding, Competitive; Cell Fractionation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Light; Models, Theoretical; Pentobarbital; Picrotoxin; Rabbits; Receptors, GABA-A; Retina | 1990 |
[The effect of glycine and gamma-aminobutyric acid on the excitatory postsynaptic potentials of the spinal motor neurons in the lamprey in the presence of antagonists].
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Fishes; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Lampreys; Membrane Potentials; Motor Neurons; Picrotoxin; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
Are GABAB receptors involved in the pharmacological effects of ethanol?
Topics: Animals; Baclofen; Cells, Cultured; Chlorine; Diazepam; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Picrotoxin; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Spinal Cord | 1990 |
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; gamma-Aminobutyric Acid; Male; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Inbred Strains | 1990 |
[The depressing effect of GABA on synaptic excitation in isolated rat hippocampal slices].
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Neurons; Penicillin G Benzathine; Picrotoxin; Rats; Receptors, Neurotransmitter; Synapses | 1990 |
Amino acid receptors from insect muscle: electrophysiological characterization in Xenopus oocytes following expression by injection of mRNA.
Topics: Amino Acids; Animals; Electrophysiology; Female; gamma-Aminobutyric Acid; Glutamates; Grasshoppers; Microinjections; Muscles; Oocytes; Picrotoxin; Poly A; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; RNA, Messenger; Xenopus laevis | 1990 |
Electrical activity and feeding correlates of intracranial hypothalamic injection of GABA, muscimol and picrotoxin in the rats.
Topics: Action Potentials; Animals; Drinking Behavior; Feeding Behavior; gamma-Aminobutyric Acid; Hypothalamus; Male; Microinjections; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Effects of gamma-aminobutyric acid on skate retinal horizontal cells: evidence for an electrogenic uptake mechanism.
Topics: Animals; Bicuculline; Biological Transport, Active; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Nipecotic Acids; Picrotoxin; Proline; Retina; Skates, Fish; Sodium | 1990 |
Bicuculline and picrotoxin block phase advances induced by GABA agonists in the circadian rhythm of locomotor activity in the golden hamster by a phaclofen-insensitive mechanism.
Topics: Animals; Baclofen; Bicuculline; Circadian Rhythm; Cricetinae; gamma-Aminobutyric Acid; Male; Mesocricetus; Microinjections; Motor Activity; Muscimol; Picrotoxin; Stereotaxic Techniques; Triazolam | 1990 |
Stimulation of 36Cl- influx into rabbit cerebral cortex microsacs by the endogenous antigen S-100.
Topics: Animals; Bicuculline; Cerebral Cortex; Chlorides; Chlorine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Picrotoxin; Rabbits; Radioisotopes; S100 Proteins | 1990 |
Influence of gamma-aminobutyric acid on the changes of blood pressure in rats.
Topics: Animals; Atropine; Blood Pressure; Chlorisondamine; Debrisoquin; Diazepam; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Prazosin; Rats; Rats, Inbred Strains | 1990 |
Whole-cell patch study of GABAergic inhibition in CA1 neurons of immature rat hippocampal slices.
Topics: Animals; Animals, Newborn; Bicuculline; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Changes in succinate dehydrogenase activity of rats after intraventricular injections of GABA, muscimol and picrotoxin.
Topics: Animals; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Succinate Dehydrogenase | 1990 |
Butyrylcholinesterase fluctuation in male albino rats with intracerebroventricular injection of gamma aminobutyric acid, muscimol, and picrotoxin.
Topics: Animals; Butyrylcholinesterase; Cholinesterases; gamma-Aminobutyric Acid; Hypothalamus; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Nervous System Diseases; Picrotoxin; Pyrrolidinones; Synaptic Membranes | 1990 |
Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons.
Topics: 4-Butyrolactone; Animals; Cells, Cultured; Electrophysiology; Furans; gamma-Aminobutyric Acid; Hippocampus; Lactones; Neurons; Picrotoxin; Receptors, Drug; Succinimides | 1990 |
Suppression of spontaneous generalized non-convulsive seizures in the rat by microinjection of GABA antagonists into the superior colliculus.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Superior Colliculi | 1990 |
GABA activates different types of chloride-conducting receptor-ionophore complexes in a dose-dependent manner.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Ion Channels; Picrotoxin; Rana catesbeiana; Receptors, GABA-A | 1985 |
Possible involvement of K+-conductance in the action of gamma-aminobutyric acid in the guinea-pig hippocampus.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Iontophoresis; Membrane Potentials; Neuromuscular Depolarizing Agents; Picrotoxin; Sodium | 1985 |
Anesthetic and convulsant barbiturates alter gamma-aminobutyric acid-stimulated chloride flux across brain membranes.
Topics: Animals; Barbiturates; Brain; Chlorides; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred DBA; Pentobarbital; Picrotoxin; Receptors, GABA-A; Stereoisomerism | 1986 |
gamma-Aminobutyric acid hyperpolarizes rat hippocampal pyramidal cells through a calcium-dependent potassium conductance.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Dendrites; Egtazic Acid; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channels; Male; Neurons; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Synaptic Transmission | 1986 |
gamma-Aminobutyric acid antagonists stimulate vasopressin release from organ-cultured hypothalamo-neurohypophyseal explants.
Topics: Acetylcholine; Animals; Bacitracin; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Ion Channels; Male; Nipecotic Acids; Organ Culture Techniques; Osmolar Concentration; Penicillins; Picrotoxin; Pituitary Gland, Posterior; Proline; Rats; Rats, Inbred Strains; Vasopressins | 1987 |
Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system.
Topics: Animals; Apomorphine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Interneurons; Male; Picrotoxin; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Tryptophan | 1987 |
GABA receptors on the cell-body membrane of an identified insect motor neuron.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Chlorides; Cockroaches; Dibenzazepines; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Potentials; Microelectrodes; Motor Neurons; Nipecotic Acids; Periplaneta; Picrotoxin; Receptors, GABA-A | 1988 |
Alpha-substituted thiobutyrolactones potentiate GABA currents in voltage-clamped chick spinal cord neurons.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cells, Cultured; Chick Embryo; Diazepam; Furans; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Phenobarbital; Picrotoxin; Spinal Cord | 1988 |
Contrasting properties of K+ conductances induced by baclofen and gamma-aminobutyric acid in slices of the guinea pig hippocampus.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Potentials; Picrotoxin; Potassium; Reference Values | 1987 |
gamma-Aminobutyric acid-induced ion movements in the guinea pig hippocampal slice.
Topics: Animals; Bicuculline; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Picrotoxin; Potassium; Sodium; Tetrodotoxin | 1989 |
Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons.
Topics: Animals; Anti-Bacterial Agents; Bicuculline; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Macrolides; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Sesterterpenes; Spinal Cord | 1989 |
Acetylcholine and GABA mediate opposing actions on neuronal chloride channels in crayfish.
Topics: Acetylcholine; Animals; Astacoidea; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Neurons; Optic Lobe, Nonmammalian; Picrotoxin | 1989 |
The rat beta 1-subunit of the GABAA receptor forms a picrotoxin-sensitive anion channel open in the absence of GABA.
Topics: Animals; Anions; Carbolines; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Macromolecular Substances; Membrane Potentials; Picrotoxin; Rats; Receptors, GABA-A; Xenopus laevis | 1989 |
Similarities between the effects of lindane (gamma-HCH) and picrotoxin on ligand-gated chloride channels in crayfish muscle membrane.
Topics: Animals; Astacoidea; Chlorides; gamma-Aminobutyric Acid; Hexachlorocyclohexane; In Vitro Techniques; Ion Channels; Muscles; Picrotoxin | 1989 |
Influence of GABA-gated bicarbonate conductance on potential, current and intracellular chloride in crayfish muscle fibres.
Topics: Animals; Astacoidea; Bicarbonates; Cell Membrane Permeability; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Mathematics; Membrane Potentials; Muscles; Picrotoxin | 1989 |
Comparison of the responses to light and to GABA of cells postsynaptic to barnacle photoreceptors (I-cells).
Topics: Animals; Bicuculline; Cations, Divalent; Cimetidine; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Guanidines; Light; Osmolar Concentration; Photoreceptor Cells; Picrotoxin; Propionates; Synapses; Thoracica | 1989 |
Genotype-dependent effects of GABAergic agents on sedative properties of ethanol.
Topics: Animals; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Genetics, Behavioral; Genotype; Hypnotics and Sedatives; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Muscimol; Pentobarbital; Picrotoxin; Species Specificity | 1989 |
GABAergic agents-induced antinociceptive effect in mice.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; Muscimol; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Valproic Acid | 1989 |
Effect of GABAergic drugs on motor impairment from ethanol, barbital and lorazepam in rat lines selected for differential sensitivity to ethanol.
Topics: Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Lorazepam; Picrotoxin; Psychomotor Performance; Rats | 1989 |
Effects of the acute and chronic administration of chlordiazepoxide on the development of spontaneous motility in chick embryos.
Topics: Animals; Bicuculline; Chick Embryo; Chlordiazepoxide; gamma-Aminobutyric Acid; Movement; Pentylenetetrazole; Picrotoxin; Strychnine; Time Factors | 1989 |
Picrotoxin effects on frog ERG at different background illumination but same stimulus contrast.
Topics: Animals; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Light; Picrotoxin; Rana ridibunda; Retina; Synapses | 1989 |
The tremorigen aflatrem is a positive allosteric modulator of the gamma-aminobutyric acidA receptor channel expressed in Xenopus oocytes.
Topics: Allosteric Regulation; Animals; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Indoles; Membrane Proteins; Mycotoxins; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Xenopus | 1989 |
Influence of GABA and ethylenediamine in the guinea-pig duodenum.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Duodenum; Electric Stimulation; Ethylenediamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Thiosemicarbazones | 1989 |
Modulation of spontaneous motility by GABAA receptor antagonism in the guinea pig isolated ileum.
Topics: 3-Mercaptopropionic Acid; Acetylcholine; Androstanes; Animals; Azasteroids; Bicuculline; Carbachol; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Picrotoxin; Time Factors | 1989 |
The modulation by chlormethiazole of the GABAA-receptor complex in rat brain.
Topics: Animals; Baclofen; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlormethiazole; CLC-2 Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A | 1989 |
Further evidence for the GABAergic influence on memory. Interaction of GABAergic transmission with angiotensin II on memory processes.
Topics: Angiotensin II; Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Muscimol; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission | 1989 |
The motor response to ethylenediamine of the rat isolated duodenum: involvement of GABAergic transmission?
Topics: 3-Mercaptopropionic Acid; Animals; Benzalkonium Compounds; Duodenum; Ethylenediamines; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Tetrodotoxin | 1989 |
An in vitro study of the relationship between GABA receptor function and propulsive motility in the distal colon of the rabbit.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Autonomic Nervous System; Baclofen; Colon; gamma-Aminobutyric Acid; Gastrointestinal Motility; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Rabbits; Receptors, GABA-A; Sesterterpenes; Taurine | 1989 |
The influence of antidepressive treatment on GABA-related mechanisms in the rat hippocampus: behavioral studies.
Topics: Animals; Behavior, Animal; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hippocampus; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical | 1989 |
An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells.
Topics: Acetylcholine; Action Potentials; Adrenal Medulla; Androstanes; Animals; Azasteroids; Bicuculline; Cattle; Cell Membrane; Chloride Channels; Chlorides; Chromaffin System; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Proteins; Picrotoxin; Propanidid; Receptors, Cholinergic; Receptors, GABA-A | 1989 |
[The electrical activity of the hippocampus in rats centrally administered GABA agonists and antagonists].
Topics: Animals; Baclofen; Bicuculline; Drug Interactions; Electrodes, Implanted; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Anatomically distinct output channels of the caudate nucleus and orofacial dyskinesia: critical role of the subcommissural part of the globus pallidus in oral dyskinesia.
Topics: Animals; Cats; Caudate Nucleus; Disease Models, Animal; Dyskinesia, Drug-Induced; Facial Muscles; gamma-Aminobutyric Acid; Globus Pallidus; Male; Neural Pathways; Picrotoxin; Receptors, GABA-A; Tongue | 1989 |
Giant synaptic potentials in immature rat CA3 hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Animals, Newborn; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Ketamine; Membrane Potentials; Phencyclidine; Picrotoxin; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
[Effects of neurotransmitters and blockers on electroretinogram c-wave and light peak of the chick].
Topics: Animals; Chickens; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Neurotransmitter Agents; Photic Stimulation; Picrotoxin; Retina; Strychnine | 1989 |
Changes in the activity of glutamate related enzymes in cerebral cortex, during insulin-induced seizures.
Topics: Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Blood Glucose; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Glutamine; Insulin; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1989 |
Bicuculline and picrotoxin block gamma-aminobutyric acid-gated Cl- conductance by different mechanisms.
Topics: Animals; Bicuculline; Binding, Competitive; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Picrotoxin; Rana catesbeiana | 1985 |
Effect of GABA muscimol and picrotoxin on electrical activity of the medial preoptic area in unanesthetized rats.
Topics: Animals; Electroencephalography; Electrophysiology; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Preoptic Area; Rats; Rats, Inbred Strains | 1989 |
Inhibition of proestrous LH surge and ovulation in rats evoked by stimulation of the medial raphe nucleus involves a GABA-mediated mechanism.
Topics: Animals; Bicuculline; Electric Stimulation; Electrodes, Implanted; Estrus; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Injections, Intraperitoneal; Injections, Intraventricular; Luteinizing Hormone; Methysergide; Ovulation; Picrotoxin; Pituitary Gland, Anterior; Proestrus; Raphe Nuclei; Rats; Serotonin | 1989 |
Neuronal activity in the subcortically denervated hippocampus: a chronic model for epilepsy.
Topics: Action Potentials; Animals; Epilepsy; Female; gamma-Aminobutyric Acid; Hippocampus; Picrotoxin; Rats; Rats, Inbred Strains | 1989 |
Convulsant gamma-butyrolactones block GABA currents in cultured chick spinal cord neurons.
Topics: 4-Butyrolactone; Animals; Cells, Cultured; Chick Embryo; Furans; gamma-Aminobutyric Acid; Membrane Potentials; Picrotoxin; Spinal Cord | 1989 |
Modulatory roles of GABAergic mechanisms in post-rotatory nystagmus in the rabbit.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Nystagmus, Pathologic; Picrotoxin; Rabbits; Rotation; Semicarbazides; Strychnine; Time Factors | 1989 |
Characterization of midline medulla role in the trigeminal depressor response.
Topics: Animals; Blood Pressure; Cats; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Heart Conduction System; Medulla Oblongata; Neural Inhibition; Neurons; Picrotoxin; Serotonin; Sympathetic Nervous System; Trigeminal Nucleus, Spinal | 1989 |
GABA- and glutamate-mediated synaptic potentials in rat dorsal raphe neurons in vitro.
Topics: Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Membranes; Muscimol; Picrotoxin; Raphe Nuclei; Rats; Synapses | 1989 |
Modulation of sympathetic discharge by a hypothalamic GABAergic mechanism.
Topics: Animals; Blood Pressure; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Injections; Muscimol; Paralysis; Picrotoxin; Sympathetic Nervous System | 1989 |
Effects of naloxone and naltrexone on memory consolidation in CD1 mice: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Naltrexone; Picrotoxin | 1989 |
Inhibitory effect of GABA on cerebrovascular sympathetic neurotransmission.
Topics: Adrenergic Fibers; Animals; Baclofen; Cerebral Arteries; Cerebrovascular Circulation; Electric Stimulation; Female; gamma-Aminobutyric Acid; Goats; Isometric Contraction; Neural Inhibition; Norepinephrine; Picrotoxin; Vasoconstriction | 1989 |
gamma-Aminobutyric acid regulation of neurohypophysial hormone secretion in male and female rats.
Topics: Animals; Arginine Vasopressin; Bicuculline; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Oxytocin; Picrotoxin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Time Factors; Veratridine | 1989 |
Qualitative and quantitative changes in monoamine oxidase activity after acute third ventricle treatment of GABA, muscimol, and picrotoxin in rat.
Topics: Animals; Brain; Cytophotometry; gamma-Aminobutyric Acid; Histocytochemistry; Injections, Intraventricular; Male; Monoamine Oxidase; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1989 |
gamma Aminobutyric acid uptake, release, and effect on 36Cl--influx in bovine pineal gland.
Topics: Alanine; Aminooxyacetic Acid; Animals; Calcium; Cattle; Chlorides; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Nipecotic Acids; Picrotoxin; Pineal Gland; Potassium; Stimulation, Chemical | 1989 |
Effects of depressant amino acids and antagonists on an in vitro spinal cord preparation from the adult rat.
Topics: Action Potentials; Amino Acids; Animals; Bicuculline; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; Picrotoxin; Piperazines; Rats; Spinal Cord; Strychnine; Synapses; Taurine; Valine | 1989 |
GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla.
Topics: Animals; Bicuculline; Dioxanes; Evoked Potentials; gamma-Aminobutyric Acid; Idazoxan; Iontophoresis; Locus Coeruleus; Male; Medulla Oblongata; Naloxone; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains | 1989 |
Behavioral aspects of GABAergic-dopaminergic interactions in the central nervous system.
Topics: 3-Mercaptopropionic Acid; Animals; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior; Strychnine; Time Factors | 1989 |
Blockade of enkephalinergic and GABAergic mediated locomotion in the nucleus accumbens by muscimol in the ventral pallidum.
Topics: Animals; Carbachol; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Globus Pallidus; Injections; Male; Motor Activity; Muscimol; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei | 1989 |
Effects of muscimol, cetyl-GABA, pentetrazol and picrotoxin on timidity during intraspecies conflict in mice.
Topics: Aggression; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pentylenetetrazole; Picrotoxin; Species Specificity | 1989 |
Ethanol potentiates the effect of gamma-aminobutyric acid on medial vestibular nucleus neurons responding to horizontal rotation.
Topics: Animals; Bicuculline; Cats; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Ethanol; gamma-Aminobutyric Acid; Male; Neural Inhibition; Neurons; Picrotoxin; Rotation; Vestibular Nuclei | 1989 |
Release pattern of endogenous dopamine in teleost retinae during light adaptation and pharmacological stimulation.
Topics: Adaptation, Ocular; Animals; Bicuculline; Carps; Chromatography, High Pressure Liquid; Cyprinidae; Dopamine; gamma-Aminobutyric Acid; Glutamates; Kynurenic Acid; Photic Stimulation; Picrotoxin; Retina; Taurine | 1989 |
Centrally administered GABA and GABA-selective agonist and antagonist in rats: histoenzymological cytophotometric study.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cytophotometry; gamma-Aminobutyric Acid; Histocytochemistry; Hypothalamus; Injections, Intraventricular; Male; Monoamine Oxidase; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Succinate Dehydrogenase | 1989 |
Effect of noradrenaline and gamma-aminobutyric acid on the secretion of corticotrophin-releasing factor-41 and arginine vasopressin from the rat hypothalamus in vitro.
Topics: Acetylcholine; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Norepinephrine; Peptide Fragments; Phentolamine; Picrotoxin; Propranolol; Rats | 1989 |
[Inhibitory effects of gamma-aminobutyric acid and diazepam on ventricular arrhythmias induced by hypothalamic electric stimulation].
Topics: Animals; Arrhythmias, Cardiac; Diazepam; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hypothalamus; Injections, Intraventricular; Male; Picrotoxin; Rabbits | 1989 |
Antagonists of GABA responses, studied using internally perfused frog dorsal root ganglion neurons.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Penicillins; Picrotoxin; Rana catesbeiana; Receptors, GABA-A; Zinc | 1987 |
Studies on [3H]GABA and endogenous GABA release in rat cerebral cortex suggest the presence of autoreceptors of the GABAB type.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Median Eminence; Nipecotic Acids; Picrotoxin; Potassium; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1987 |
Neuroeffector mechanisms in the voiding cycle of the guinea-pig urinary bladder.
Topics: Animals; Atropine; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Neuroeffector Junction; Physostigmine; Picrotoxin; Receptors, Cholinergic; Receptors, GABA-A; Synaptic Transmission; Urinary Bladder; Urodynamics | 1987 |
Effects of ethanol on passive avoidance behavior in the mouse: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Male; Memory; Mice; Muscimol; Picrotoxin; Receptors, GABA-A | 1988 |
Kinetic modulation by GABAergic agents of high- and low-affinity binding of [3H]methyl beta-carboline-3-carboxylate.
Topics: Androstanes; Animals; Azasteroids; Carbolines; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Half-Life; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1988 |
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1988 |
Single subunits of the GABAA receptor form ion channels with properties of the native receptor.
Topics: Animals; Chloride Channels; Chlorides; Cloning, Molecular; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Macromolecular Substances; Membrane Proteins; Picrotoxin; Receptors, GABA-A; RNA, Messenger; Structure-Activity Relationship; Xenopus laevis | 1988 |
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Indomethacin; Male; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Taurine | 1988 |
Direct evidence for the presence of GABAA receptors on the cytoplasmic side of the Deiters' neurone membrane.
Topics: Animals; Bicuculline; Chlorides; Cytoplasm; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A | 1988 |
Two inhibitory postsynaptic potentials, and GABAA and GABAB receptor-mediated responses in neocortex of rat and cat.
Topics: Action Potentials; Animals; Baclofen; Barium; Bicuculline; Cats; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Neurons; Picrotoxin; Rats; Receptors, GABA-A; Somatosensory Cortex; Synapses; Time Factors; Visual Cortex | 1988 |
[The GABA-ergic system and brain edema].
Topics: Animals; Anti-Anxiety Agents; Benactyzine; Benzodiazepines; Benzodiazepinones; Brain Edema; Brain Injuries; Diazepam; Drug Evaluation, Preclinical; Drug Interactions; Female; gamma-Aminobutyric Acid; Male; Nicotine; Parasympatholytics; Phentolamine; Picrotoxin; Rats; Receptors, GABA-A | 1985 |
Central GABA-ergic mechanism in stress-induced gastric ulceration.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cold Temperature; Epinephrine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Injections, Intraventricular; Male; Neurotransmitter Agents; Picrotoxin; Pylorus; Rats; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Valproic Acid | 1985 |
Somatostatin and GABA correlate with cervical autonomic nerve activity.
Topics: Animals; Atropine; Autonomic Nervous System; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Hemodynamics; Injections, Intraventricular; Laryngeal Nerves; Male; Picrotoxin; Rats; Rats, Inbred Strains; Reserpine; Somatostatin | 1985 |
Modulation of neurotransmitter action: control of the gamma-aminobutyric acid response through the benzodiazepine receptor.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Carbolines; Chick Embryo; Electric Conductivity; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Neurotransmitter Agents; Picrotoxin; Pyridazines; Receptors, GABA-A | 1985 |
Somatostatin secretion from the hypothalamus.
Topics: Animals; Carbachol; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Hypothalamus; Immunologic Techniques; Membrane Potentials; Muscimol; Norepinephrine; Picrotoxin; Potassium; Rats; Secretory Rate; Sesterterpenes; Somatostatin; Tetradecanoylphorbol Acetate | 1985 |
Involvement of noradrenaline in potentiation of the head-twitch response by GABA-related drugs.
Topics: Adrenergic beta-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Diazepam; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; Male; Methoxydimethyltryptamines; Metoprolol; Mice; Muscimol; Norepinephrine; Pentobarbital; Picrotoxin; Stereotyped Behavior; Taurine | 1986 |
Involvement of neuronal cell bodies of the mesencephalic locomotor region in the initiation of locomotor activity of freely behaving rats.
Topics: Amphetamine; Animals; Behavior, Animal; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Mesencephalon; Motor Activity; Neurons; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
Biphasic effects of glycine on synaptic responses of the frog optic tectum in vitro.
Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Picrotoxin; Rana temporaria; Superior Colliculi; Synapses; Synaptic Transmission | 1986 |
Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Bicuculline; Carbolines; Cells, Cultured; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Nitrazepam; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1986 |
The role of GABA and excitatory amino acids in the development of the leptazol-induced epileptogenic EEG.
Topics: Allylglycine; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Clonazepam; Dose-Response Relationship, Drug; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1986 |
Evidence for the activation of the N-methyl-D-aspartate receptor during epileptiform discharge.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Epilepsy; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Neural Inhibition; Picrotoxin; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Synaptic Transmission; Valine | 1986 |
Efflux of putative transmitters from superfused rat brain slices induced by low chloride ion concentrations.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Anions; Calcium; Cerebral Cortex; Chlorides; Female; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Rats; Rats, Inbred Strains; Serotonin; Strychnine; Tetrodotoxin | 1987 |
Effects of barbiturates on the inhibitory action of GABA on excitatory response of the stomach to stimulation of vagal afferent fibers in cat.
Topics: Afferent Pathways; Animals; Bicuculline; Cats; Chloralose; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hexamethonium; Hexamethonium Compounds; Kinetics; Male; Phenobarbital; Picrotoxin; Stomach; Vagus Nerve | 1987 |
[3H]Ro 15-1788 binding to benzodiazepine receptors in mouse brain in vivo: marked enhancement by GABA agonists and other CNS drugs.
Topics: Animals; Antipsychotic Agents; Barbiturates; Brain; Buspirone; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intravenous; Male; Mice; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vasodilator Agents | 1987 |
GABAergic, dopaminergic and cholinergic interaction in tremorine-induced tremors in mice.
Topics: Animals; Bicuculline; Bromocriptine; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Parasympathetic Nervous System; Picrotoxin; Scopolamine; Tremor; Tremorine | 1988 |
Pharmacologically induced changes in the latency of digastric reflexes in 1-7 day old rabbits.
Topics: Animals; Animals, Newborn; Bicuculline; Decerebrate State; Diazepam; Electromyography; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rabbits; Reflex; Stomach; Strychnine; Synaptic Transmission | 1988 |
Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Aspartic Acid; Basal Ganglia; Brain; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata; Synaptic Transmission | 1988 |
Sex differences in the response of rats to drugs affecting GABAergic transmission.
Topics: Animals; Corticosterone; Diazepam; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sex Characteristics; Synaptic Transmission | 1985 |
Role of the cat substantia nigra pars reticulata in eye and head movements. II. Effects of local pharmacological injections.
Topics: Animals; Bicuculline; Cats; Eye Movements; gamma-Aminobutyric Acid; Movement; Muscimol; Orientation; Picrotoxin; Reflex; Substantia Nigra; Synaptic Transmission | 1985 |
The picrotoxinin binding site and its relationship to the GABA receptor complex.
Topics: Acetates; Acetic Acid; Animals; Brain; Chlorides; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Picrotoxin; Rats; Receptors, GABA-A; Sesterterpenes; Sodium | 1985 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
Light evoked release of acetylcholine in response to a single flash: cholinergic amacrine cells receive ON and OFF input.
Topics: Acetylcholine; Animals; Atropine; Cholinergic Fibers; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; Picrotoxin; Rabbits; Retina; Synaptic Transmission; Vision, Ocular | 1985 |
GABAA and GABAB receptors in detrusor strips from guinea-pig bladder dome.
Topics: Animals; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
Inhibitory effect of cholesteryl gamma-aminobutyrate on evoked activity in rat hippocampal slices.
Topics: Animals; Blood-Brain Barrier; Cholesterol Esters; Depression, Chemical; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Hydrolysis; In Vitro Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Effect of GABA and its antagonists, bicuculline and picrotoxin, on nerve cell discharges of the photosensory pineal organ of the frog, Rana esculenta.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Light; Picrotoxin; Pineal Gland; Rana esculenta; Synaptic Transmission | 1985 |
Inhibitory effect of GABA on sympathetic neurotransmission in rabbit ear artery.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Arteries; Baclofen; Ear, External; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Norepinephrine; Picrotoxin; Potassium; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Taurine; Vasoconstriction | 1985 |
Modulatory activity of GABAB receptors on cholinergic tone in guinea-pig distal colon.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Atropine; Baclofen; Bicuculline; Blood Pressure; Colon; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Male; Parasympathetic Nervous System; Picrotoxin; Receptors, GABA-A | 1985 |
Evidence for gamma-aminobutyric acid mediation of the sympathetic nerve inhibitory response to vagal afferent stimulation.
Topics: Afferent Pathways; Animals; Bicuculline; Blood Pressure; Cats; Diazepam; Female; gamma-Aminobutyric Acid; Heart; Male; Neural Inhibition; Picrotoxin; Receptors, GABA-A; Reflex; Sympathetic Nervous System; Urethane; Vagus Nerve | 1985 |
gamma-Aminobutyric acid partly mediates the pentobarbitone depression of synaptic excitation in the guinea-pig olfactory cortex in vitro.
Topics: Animals; Bicuculline; Drug Interactions; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Limbic System; Male; Membrane Potentials; Olfactory Pathways; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1985 |
Dual effect of GABA on the contractile activity of the guinea-pig isolated urinary bladder.
Topics: Acetylcholine; Animals; Baclofen; Dimethylphenylpiperazinium Iodide; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
Evidence for GABA mediation of sympathetic inhibition evoked from midline medullary depressor sites.
Topics: Animals; Bicuculline; Brain Mapping; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Neural Inhibition; Picrotoxin; Raphe Nuclei; Serotonin; Synaptic Transmission; Vasomotor System | 1985 |
An unusual effect of gamma-aminobutyric acid on synaptic transmission of frog tectal neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Hot Temperature; In Vitro Techniques; Muscimol; Neurons; Optic Nerve; Picrotoxin; Rana temporaria; Strychnine; Superior Colliculi; Synaptic Transmission | 1985 |
Inhibition of intrathecally administered picrotoxin- and bicuculline-induced convulsions in mice by pipecolic acid or GABA.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Nipecotic Acids; Picrotoxin; Pipecolic Acids; Proline; Receptors, GABA-A; Seizures; Strychnine | 1985 |
[Nature of a mediator participating in reflex inhibition of the activity of the lymphatic center of the frog].
Topics: Ammonium Chloride; Animals; Bicuculline; Furosemide; gamma-Aminobutyric Acid; In Vitro Techniques; Lymphatic System; Neural Inhibition; Picrotoxin; Rana temporaria; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1985 |
[Ionic mechanisms of the effects of phenibut and GABA unrelated to changes in the function of chloride channels].
Topics: Animals; Anterior Horn Cells; Chlorides; Cyclic AMP; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Motor Neurons; Picrotoxin; Potassium; Rats; Receptors, GABA-A; Reflex; Sodium; Theophylline | 1985 |
Effect of picrotoxinin on benzodiazepine receptor binding.
Topics: Animals; Brain; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1985 |
Memory effects of GABA-ergic antagonists in rats trained with two-way active avoidance tasks.
Topics: Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Picrotoxin; Rats; Rats, Inbred Strains; Synaptic Transmission | 1985 |
Involvement of bicuculline-insensitive receptors in the hypothermic effect of GABA and its agonists.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Body Temperature; Drug Interactions; Female; gamma-Aminobutyric Acid; Hypothermia; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors; Valproic Acid | 1985 |
Neurotoxic insecticides inhibit GABA-dependent chloride uptake by mouse brain vesicles.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Insecticides; Male; Mice; Mice, Inbred ICR; Picrotoxin; Receptors, GABA-A | 1985 |
[Effect of gamma-aminobutyric acid on neurons of the spinal lymphatic center].
Topics: Ammonium Chloride; Animals; Bicuculline; Furosemide; gamma-Aminobutyric Acid; Lymphatic System; Picrotoxin; Rana temporaria; Spinal Cord; Synaptic Transmission | 1985 |
GABA antagonists increase the release of [3H]acetylcholine from the chick retina.
Topics: Acetylcholine; Animals; Bicuculline; Chickens; Choline; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Haloperidol; In Vitro Techniques; Photic Stimulation; Picrotoxin; Potassium; Receptors, GABA-A; Retina; Strychnine | 1986 |
Non involvement of gamma-aminobutyric acid in catechol-induced seizures.
Topics: Animals; Carbachol; Diazepam; Female; gamma-Aminobutyric Acid; Mice; Muscles; Phenobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Valproic Acid | 1986 |
Gamma aminobutyric acid mediates ventromedial hypothalamic mechanisms controlling the execution of lordotic responses in the female rat.
Topics: Action Potentials; Animals; Brain Mapping; Female; gamma-Aminobutyric Acid; Lidocaine; Picrotoxin; Posture; Rats; Sexual Behavior, Animal; Synaptic Transmission; Ventromedial Hypothalamic Nucleus | 1986 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
Lordosis behavior and GABAergic neurotransmission.
Topics: Adrenalectomy; Animals; Estradiol; Female; gamma-Aminobutyric Acid; Hypothalamus; Injections; Ovariectomy; Picrotoxin; Posture; Progesterone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Synaptic Transmission | 1986 |
Effect of ethanol on the binding of 35S-T-butylbicyclophosphorothionate to mouse brain membranes.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cell Membrane; Cerebellum; Cerebral Cortex; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Picrotoxin; Receptors, GABA-A | 1986 |
GABAergic control of masculine sexual behavior.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Caudate Nucleus; Ethanolamines; gamma-Aminobutyric Acid; Male; Picrotoxin; Preoptic Area; Putamen; Rats; Sexual Behavior, Animal; Synaptic Transmission | 1986 |
Activation of GABA receptors in the hypothalamus stimulates secretion of growth hormone and prolactin.
Topics: Animals; Anterior Hypothalamic Nucleus; Bicuculline; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; Male; Microinjections; Muscimol; Picrotoxin; Preoptic Area; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Midazolam cue in rats: effects of Ro 15-1788 and picrotoxin.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Nicotine; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1986 |
Dopamine-GABA interactions: evidence that GABA transmits, modulates and mediates dopaminergic functions in the basal ganglia and the limbic system.
Topics: Amygdala; Animals; Basal Ganglia; Behavior, Animal; Benzodiazepines; Catalepsy; Corpus Striatum; Dopamine; Drug Interactions; Efferent Pathways; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Limbic System; Movement Disorders; Muscimol; Nucleus Accumbens; Picrotoxin; Posture; Receptors, Dopamine; Receptors, GABA-A; Substantia Nigra; Tegmentum Mesencephali; Thalamic Nuclei | 1986 |
The colliculus superior modulates ACTH-induced excessive grooming.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Cosyntropin; GABA Antagonists; gamma-Aminobutyric Acid; Grooming; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Superior Colliculi | 1986 |
The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.
Topics: Animals; Bicuculline; Body Temperature; Carbolines; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1986 |
GABA-serotonergic interactions in the regulation of central sympathetic pathways.
Topics: Animals; Blood Pressure; Cats; Central Nervous System; Clonidine; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Methysergide; Picrotoxin; Serotonin; Sympathetic Nervous System; Synaptic Transmission | 1986 |
GABAergic neurotransmission within the reticular part of the substantia nigra (SNR): role for switching motor patterns and performance of movements.
Topics: Animals; Cats; Electromyography; Female; gamma-Aminobutyric Acid; Male; Microinjections; Motor Neurons; Movement; Picrotoxin; Substantia Nigra; Synaptic Transmission | 1986 |
Effects of picrotoxin on the turtle's electroretinogram under different background illumination.
Topics: Animals; Electroretinography; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Retina; Synaptic Transmission; Turtles | 1986 |
Nociceptive responses to altered GABAergic activity at the spinal cord.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Spinal; Motor Activity; Muscimol; Pain; Pain Measurement; Physical Stimulation; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds; Tail; Vocalization, Animal | 1986 |
Expression of vertebrate amino acid receptors in Xenopus oocytes.
Topics: Animals; Bicuculline; Chick Embryo; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression Regulation; Picrotoxin; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA, Messenger; Strychnine; Xenopus laevis | 1986 |
Potentiation of salivary fluid secretion in ixodid ticks: a new receptor system for gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Dopamine; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Picrotoxin; Receptors, GABA-A; Saliva; Spiperone; Sulpiride; Ticks | 1986 |
gamma-Aminobutyric acid-activated 36Cl- influx: a functional in vitro assay for CNS gamma-aminobutyric acid receptors of insects.
Topics: Animals; Bicuculline; Chlorides; Cockroaches; Electrophysiology; gamma-Aminobutyric Acid; Nervous System; Periplaneta; Picrotoxin; Receptors, GABA-A | 1987 |
GABA-ergic control of alpha-melanocyte-stimulating hormone (alpha-MSH) release by frog neurointermediate lobe in vitro.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunoenzyme Techniques; Male; Melanocyte-Stimulating Hormones; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Rana ridibunda; Synaptic Transmission | 1986 |
Characterization of gamma-aminobutyric acid receptors in the neurointermediate lobe of the amphibian Xenopus laevis.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Kinetics; Melanocyte-Stimulating Hormones; Picrotoxin; Pituitary Gland; Receptors, GABA-A; Taurine; Xenopus | 1987 |
N-methylaspartate receptors mediate epileptiform activity evoked in some, but not all, conditions in rat neocortical slices.
Topics: Animals; Cerebral Cortex; Epilepsy; gamma-Aminobutyric Acid; Magnesium; Male; Membrane Potentials; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Recruitment, Neurophysiological; Synaptic Transmission | 1986 |
Cyclodiene insecticides inhibit GABAA receptor-regulated chloride transport.
Topics: Animals; Bicuculline; Biological Transport; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Insecticides; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1987 |
Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats.
Topics: Aggression; Animals; Bicuculline; Brain Mapping; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Posterior; Isoniazid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Synaptic Transmission | 1987 |
Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Ethanolamines; Flurazepam; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Pentobarbital; Picrotoxin; Potassium; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
GABA and behavioral inhibition in the neonatal rat pup.
Topics: Animals; Animals, Newborn; Behavior, Animal; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Rats | 1986 |
Evidence for a dual effect of gamma-aminobutyric acid on thyrotropin (TSH)-releasing hormone-induced TSH release from perifused rat pituitaries.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Pyridazines; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone | 1987 |
Valproate enhances inhibitory postsynaptic potentials in hippocampal neurons in vitro.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Picrotoxin; Synapses; Valproic Acid | 1987 |
Microinjection of GABA antagonists into the posterior hypothalamus elicits locomotor activity and a cardiorespiratory activation.
Topics: Animals; Bicuculline; Blood Pressure; Carbon Dioxide; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Microinjections; Muscimol; Picrotoxin; Respiration; Tidal Volume | 1988 |
Rat milk stimulates pituitary growth hormone secretion of neonatal pituitaries in vitro.
Topics: Animals; Animals, Newborn; GABA Antagonists; gamma-Aminobutyric Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Milk; Oxytocin; Picrotoxin; Pituitary Gland; Rats; Thyrotropin-Releasing Hormone | 1988 |
Pharmacological evidence that effects of vasotocin on brain maturation are mediated by GABA mechanisms.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Lipid Metabolism; Organ Size; Picrotoxin; Rats; Rats, Inbred Strains; Sleep; Valproic Acid; Vasotocin | 1986 |
Changes in GABA content of the brain and sensitivity to GABA-antagonists during and after repetitive treatment of rats with diphenilhydantoin.
Topics: Animals; Brain; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1988 |
Functional classification of different dopamine receptors.
Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain; Dominance, Cerebral; Dopamine; Ergolines; Flupenthixol; gamma-Aminobutyric Acid; Hydroxydopamines; Kainic Acid; Oxidopamine; Pergolide; Picrotoxin; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Synapses | 1985 |
Comparison between pentobarbital- and muscimol-induced feeding in satiated sheep.
Topics: Aminocaproates; Animals; Calcium; Eating; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep; Sodium; Vigabatrin | 1988 |
Amygdaloid kindling with bicuculline methiodide in rats.
Topics: Amygdala; Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Pentobarbital augments serotonin-mediated inhibition of cerebellar Purkinje cells.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Male; Neural Inhibition; Pentobarbital; Pentylenetetrazole; Picrotoxin; Purkinje Cells; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture.
Topics: Animals; Bicuculline; Cells, Cultured; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Mice; Mice, Inbred C57BL; Picrotoxin; Rats; Retina; Retinal Ganglion Cells; Strychnine; Taurine | 1988 |
Alfaxalone potentiates and mimics GABA-induced contractile responses in the guinea-pig isolated ileum.
Topics: Anesthetics; Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Picrotoxin; Pregnanediones; Sesterterpenes | 1988 |
GABAergic inhibition and epileptiform discharges in the turtle hippocampus in vitro.
Topics: Afferent Pathways; Animals; Bicuculline; Electric Stimulation; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Pipecolic Acids; Pyramidal Tracts; Reference Values; Synapses; Turtles | 1988 |
Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice.
Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Ethanol; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Picrotoxin; Seizures; Substance Withdrawal Syndrome | 1988 |
Effects of the novel compound NIK-247 on impairment of passive avoidance response in mice.
Topics: Aminoquinolines; Amnesia; Animals; Avoidance Learning; Choline; Cholinesterase Inhibitors; Cycloheximide; Electroshock; gamma-Aminobutyric Acid; Male; Memory; Mice; Phencyclidine; Picrotoxin; Tacrine | 1988 |
GABAergic inhibition on dopamine cells of the fish retina: a [3H]dopamine release study with isolated fractions.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Bicuculline; Calcium; Carps; Cyprinidae; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Picrotoxin; Potassium; Retina | 1988 |
"Intracellular" GABA affects the equilibrium distribution of Cl- across the plasma membrane of a GABA acceptive neuron.
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; gamma-Aminobutyric Acid; Intracellular Membranes; Neurons; Picrotoxin; Time Factors; Vestibular Nucleus, Lateral | 1988 |
GABAergic mechanisms mediating rotational behavior in rats: differences between dorsal and ventral striatum.
Topics: Animals; Corpus Striatum; Dextroamphetamine; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Dopamine function in the prefrontal cortex of the rat is sensitive to a reduction of tonic GABA-mediated inhibition in the thalamic mediodorsal nucleus.
Topics: Animals; Bicuculline; Dopamine; Frontal Lobe; gamma-Aminobutyric Acid; Ibotenic Acid; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains; Thalamic Nuclei | 1988 |
Circadian regulation of retinomotor movements: II. The role of GABA in the regulation of cone position.
Topics: Animals; Bicuculline; Circadian Rhythm; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Melatonin; Muscimol; Photoreceptor Cells; Picrotoxin; Xenopus laevis | 1988 |
A GABAergic mechanism in the posterior hypothalamus modulates baroreflex bradycardia.
Topics: Animals; Bradycardia; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Posterior; Muscimol; Picrotoxin; Pressoreceptors; Rats; Rats, Inbred Strains | 1988 |
Center-surround, orientation, and directional properties of turtle retinal horizontal cells.
Topics: Animals; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Models, Neurological; Picrotoxin; Retina; Retinal Ganglion Cells; Synapses; Turtles | 1988 |
Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation.
Topics: 3-Mercaptopropionic Acid; Anesthesia; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Male; Pentobarbital; Pentylenetetrazole; Perfusion; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Biphasic responses of thalamic neurons to GABA in isolated rat brain slices--II.
Topics: Animals; Bicuculline; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Picrotoxin; Rats; Thalamus | 1988 |
The rabbit electroretinogram: effect of GABA and its antagonists.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Photic Stimulation; Picrotoxin; Rabbits; Retina; Time Factors | 1988 |
GABA responses in rat dentate granule neurons are mediated by chloride.
Topics: Animals; Chlorides; Dendrites; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Gamma-vinyl GABA: comparison of neurochemical and anticonvulsant effects in mice.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Injections; Isoniazid; Mice; Osmolar Concentration; Pentylenetetrazole; Picrotoxin; Seizures; Vigabatrin | 1988 |
Uptake in brain and neurophysiological activity of two lipid esters of gamma-aminobutyric acid.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Picrotoxin; Rats; Rats, Inbred Strains; Triglycerides | 1988 |
Effect of gamma-aminobutyric acid on human jejunum "in vitro".
Topics: Baclofen; gamma-Aminobutyric Acid; Gastrointestinal Motility; Humans; In Vitro Techniques; Jejunum; Muscle, Smooth; Picrotoxin | 1988 |
gamma-Aminobutyric acid antagonist blocks baroreceptor-activated inhibition of neurosecretory cells in the hypothalamic paraventricular nucleus of rats.
Topics: Action Potentials; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neurosecretory Systems; Paraventricular Hypothalamic Nucleus; Phenylephrine; Picrotoxin; Pressoreceptors; Rats; Rats, Inbred Strains; Strychnine | 1987 |
Progabide, a GABA mimetic drug, stimulates the secretion of plasma corticosterone in rats.
Topics: Animals; Anticonvulsants; Clonidine; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1987 |
GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Morphine; Neurons; Nociceptors; Oxazoles; Periaqueductal Gray; Picrotoxin; Raphe Nuclei; Rats; Rats, Inbred Strains | 1987 |
GABA-ergic mechanisms in the anticonvulsive activity of newly-synthesized barbiturates. I. Effects of barbiturates on the convulsive action of GABA-antagonists.
Topics: 3-Mercaptopropionic Acid; Allylglycine; Animals; Anticonvulsants; Barbiturates; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Picrotoxin; Rats; Seizures; Semicarbazides | 1987 |
The interaction between endogenous opioid peptides and GABA in lower brain stem.
Topics: Animals; Blood Pressure; Brain Stem; Cardiovascular System; Drug Synergism; Electrocardiography; Endorphins; Female; gamma-Aminobutyric Acid; Male; Naloxone; Picrotoxin; Rabbits | 1987 |
Motility and drug susceptibility of Angiostrongylus cantonensis developing from gamma-irradiated first-stage larvae.
Topics: Angiostrongylus; Animals; Autonomic Agents; Convulsants; Dibenzylchlorethamine; Female; Gamma Rays; gamma-Aminobutyric Acid; Larva; Male; Metastrongyloidea; Movement; Phenylephrine; Physostigmine; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1987 |
A simple in vitro method to study the trigeminal ganglion.
Topics: Action Potentials; Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rats; Trigeminal Ganglion; Trigeminal Nerve | 1986 |
Is GABA an afferent transmitter in the vestibular system?
Topics: Afferent Pathways; Ambystoma mexicanum; Animals; Bicuculline; Electric Stimulation; Evoked Potentials, Auditory; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Nerve Fibers; Picrotoxin; Vestibule, Labyrinth | 1987 |
Voltage-clamp studies of the inhibition of gamma-aminobutyric acid response by glucocorticoids in bullfrog primary afferent neurons.
Topics: Afferent Pathways; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Kinetics; Neurons; Picrotoxin; Prednisolone; Rana catesbeiana | 1987 |
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurons, Afferent; Pentobarbital; Picrotoxin; Rana catesbeiana | 1987 |
In vitro studies of the role of gamma-aminobutyric acid in inhibition in the lateral septum of the rat.
Topics: Animals; Bicuculline; Brain; Calcium; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Reference Values; Tetrodotoxin | 1987 |
Spinal and supraspinal components of GABAergic inhibition of the micturition reflex in rats.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Taurine; Urination | 1987 |
Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on GABA-mediated chloride uptake.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cerebral Cortex; Chlorides; Convulsants; Female; Furans; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Structure-Activity Relationship | 1987 |
gamma-Aminobutyric acid stimulates pituitary growth hormone secretion in the neonatal rat. A superfusion study.
Topics: Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; In Vitro Techniques; Kinetics; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Rats; Rats, Inbred Strains | 1987 |
[Interaction of binding sites of bicyclic esters of phosphoric acids, picrotoxin and (3H)-gamma-aminobutyric acid].
Topics: Allosteric Regulation; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cell Membrane; gamma-Aminobutyric Acid; Organophosphates; Organophosphorus Compounds; Picrotoxin; Rats; Rats, Inbred Strains | 1987 |
Uptake inhibitors potentiate gamma-aminobutyric acid-induced contractile responses in the isolated ileum of the guinea-pig.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Sesterterpenes; Taurine | 1987 |
Multiple mechanisms of antagonism of gamma-aminobutyric acid (GABA) responses.
Topics: Animals; Bicuculline; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Penicillins; Picrotoxin; Ranidae; Zinc | 1987 |
Participation of angiotensin II in learning and memory. III. Interactions of angiotensin II with GABAergic drugs.
Topics: Angiotensin II; Animals; Bicuculline; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Intraventricular; Learning; Male; Memory; Picrotoxin; Rats; Rats, Inbred Strains | 1987 |
[Role of cortical inhibition in heterosensory interaction of neurons of the sensomotor cortex of the cat].
Topics: Animals; Auditory Perception; Cats; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Motor Cortex; Neural Inhibition; Picrotoxin; Sensation; Somatosensory Cortex; Touch; Visual Perception | 1987 |
Lesions of the dorsomedial nucleus of the thalamus, medial prefrontal cortex and pedunculopontine nucleus: effects on locomotor activity mediated by nucleus accumbens-ventral pallidal circuitry.
Topics: Animals; Apomorphine; Dopamine; Dorsomedial Hypothalamic Nucleus; Efferent Pathways; Frontal Lobe; gamma-Aminobutyric Acid; Globus Pallidus; Motor Activity; Nucleus Accumbens; Picrotoxin; Pons; Rats; Rats, Inbred Strains; Septal Nuclei | 1987 |
Accelerated neural network formation in rat cerebral cortex cultures chronically disinhibited with picrotoxin.
Topics: Action Potentials; Animals; Axons; Cells, Cultured; gamma-Aminobutyric Acid; Microscopy, Electron; Nerve Net; Nervous System; Neural Inhibition; Occipital Lobe; Picrotoxin; Rats; Synapses; Time Factors | 1987 |
Specific binding of 36Cl- ions to rat cerebellar membranes: effect of GABA and S-100 protein.
Topics: Animals; Bicuculline; Cerebellum; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Male; Membranes; Picrotoxin; Rats; Rats, Inbred Strains; S100 Proteins; Synaptic Membranes | 1987 |
The interrelationship between superior colliculus and substantia nigra pars reticulata in programming movements of cats: a follow-up.
Topics: Animals; Brain Mapping; Cats; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Psychomotor Performance; Substantia Nigra; Superior Colliculi | 1987 |
GABA and glycine modify the balance of rod and cone inputs to horizontal cells in the Xenopus retina.
Topics: Animals; Cobalt; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Photic Stimulation; Photoreceptor Cells; Picrotoxin; Retina; Strychnine; Xenopus | 1987 |
Gamma-aminobutyric acid- and picrotoxin-induced changes in c-wave and light peak of retinal potentials in the chick.
Topics: Animals; Animals, Newborn; Chickens; Dose-Response Relationship, Drug; Electroretinography; gamma-Aminobutyric Acid; Picrotoxin; Retina | 1987 |
In vivo effects of gamma-aminobutyric acid on the urinary bladder contraction accompanying micturition.
Topics: Aminooxyacetic Acid; Animals; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Hexamethonium Compounds; Male; Muscimol; Neurons, Efferent; Picrotoxin; Rats; Rats, Inbred Strains; Semicarbazides; Urinary Bladder; Urination | 1987 |
Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals.
Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Muscimol; Norepinephrine; Penbutolol; Picrotoxin; Prazosin; Rats; Rats, Inbred Strains | 1987 |
Circling behavior in honey bees.
Topics: Acetylcholine; Action Potentials; Animals; Bees; Brain; GABA Antagonists; Gallamine Triethiodide; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Stereotyped Behavior | 1987 |
Elicitation of intraspecific defensive behaviors in the rat by microinjection of picrotoxin, a gamma-aminobutyric acid antagonist, into the midbrain periaqueductal gray matter.
Topics: Aggression; Animals; Brain Mapping; gamma-Aminobutyric Acid; Male; Microinjections; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
Effect of GABAergic drugs in the behavioral 'despair' test in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Muscimol; Oxazoles; Picrotoxin; Rats | 1986 |
Behavioral function of GABA in the median raphe nucleus.
Topics: Animals; Bicuculline; Cyproheptadine; Dihydrotestosterone; GABA Antagonists; gamma-Aminobutyric Acid; Haloperidol; Lysergic Acid Diethylamide; Male; Motor Activity; Muscimol; Picrotoxin; Raphe Nuclei; Rats | 1986 |
A GABA-activated chloride-conductance not blocked by picrotoxin on spiny lobster neuromuscular preparations.
Topics: Action Potentials; Animals; Chlorides; Drug Resistance; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Muscimol; Nephropidae; Neuromuscular Junction; Picrotoxin; Species Specificity | 1986 |
Effects of morphine on hexamethonium-sensitive and -resistant excitatory responses of stomach to stimulation of vagal trunk in cats.
Topics: Animals; Cats; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Male; Morphine; Picrotoxin; Stomach; Time Factors; Vagus Nerve | 1986 |
Asymmetric diffusion into the postsynaptic neuron: an extremely efficient mechanism for removing excess GABA from synaptic clefts on the Deiters' neurone plasma membrane.
Topics: Animals; Biological Transport; Cell Membrane; Diazepam; Diffusion; gamma-Aminobutyric Acid; Mathematics; Muscimol; Neurons; Picrotoxin; Rabbits; Sodium; Synapses; Vestibular Nuclei; Vestibular Nucleus, Lateral | 1986 |
Differences in cardiovascular responses to peripherally administered GABA as influenced by basal conditions and type of anaesthesia.
Topics: Adrenal Medulla; Adrenalectomy; Anesthesia; Animals; Barbital; Bicuculline; Blood Pressure; Catecholamines; gamma-Aminobutyric Acid; Guinea Pigs; Heart Rate; Hemodynamics; Hexamethonium Compounds; Male; Myocardial Contraction; Picrotoxin; Reserpine; Urethane | 1986 |
Effects of gamma-aminobutyric acid on isolated cone photoreceptors of the turtle retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Photoreceptor Cells; Picrotoxin; Time Factors; Turtles | 1986 |
A GABA cardiovascular mechanism in the dorsal raphe of the rat.
Topics: Animals; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Picrotoxin; Raphe Nuclei; Rats; Rats, Inbred Strains | 1986 |
Antagonism of acute feeding response to 2-deoxyglucose and 5-thioglucose by GABA antagonists: the relative role of ventromedial and lateral hypothalamus.
Topics: Animals; Bicuculline; Deoxy Sugars; Deoxyglucose; Feeding Behavior; gamma-Aminobutyric Acid; Glucose; Hypothalamic Area, Lateral; Hypothalamus; Hypothalamus, Middle; Male; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
Antinociceptive action of picrotoxin in the mouse.
Topics: Analgesics; Animals; Atropine; Enkephalins; GABA Antagonists; gamma-Aminobutyric Acid; Male; Methysergide; Mice; Naloxone; Picrotoxin | 1986 |
Kindling induced changes in EEG recorded during stimulation from the site of stimulation: collapse of GABA-mediated inhibition and onset of rhythmic synchronous burst.
Topics: Action Potentials; Amygdala; Animals; Bicuculline; Carbolines; Cerebral Cortex; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
GABAergic drugs can enhance or attenuate chlordiazepoxide-induced sleep time in a heterogeneous strain of mice.
Topics: Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Chlordiazepoxide; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Pentylenetetrazole; Picrotoxin; Sleep | 1986 |
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission.
Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Morphine; Muscimol; Neural Pathways; Pain; Pain Measurement; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
Increase in catecholamine release and 45Ca2+ uptake induced by GABA in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Bicuculline; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; gamma-Aminobutyric Acid; Nifedipine; Picrotoxin | 1986 |
Effects of GABA natriuresis induced centrally by cholinergic stimulation.
Topics: Animals; Atropine; Carbachol; Cerebral Ventricles; gamma-Aminobutyric Acid; Injections, Intraventricular; Kinetics; Male; Natriuresis; Picrotoxin; Potassium; Rats; Rats, Inbred Strains | 1987 |
[Analysis of the depressant effect of diazepam on the amplitude of phrenic nerve discharge in rabbits].
Topics: Action Potentials; Animals; Blood Pressure; Cyproheptadine; Depression, Chemical; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Naloxone; Phrenic Nerve; Picrotoxin; Rabbits | 1985 |
Computer analysis of vestibular responses to putative neurotransmitters.
Topics: Animals; Carbachol; gamma-Aminobutyric Acid; Microcomputers; Neurophysiology; Picrotoxin; Rana catesbeiana; Semicircular Canals; Software; Vestibular Nerve | 1985 |
Dopamine inhibits calcium-independent gamma-[3H]aminobutyric acid release induced by kainate and high K+ in the fish retina.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Dopamine; Fishes; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; N-Methylaspartate; Oxadiazoles; Picrotoxin; Potassium; Pyrrolidines; Quisqualic Acid; Retina; Serotonin | 1985 |
Biphasic effects of systemically administered GABA antagonists on cardiac vagal activity.
Topics: Animals; Blood Pressure; Cardiovascular System; Central Nervous System; Decerebrate State; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Nervous System; Picrotoxin; Rats; Rats, Inbred Strains; Vagus Nerve | 1986 |
Pharmacological modification of the light-induced responses of Müller (glial) cells in the amphibian retina.
Topics: Aminobutyrates; Animals; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Light; Membrane Potentials; Neuroglia; Picrotoxin; Retina; Tetrodotoxin; Veratrine; Xenopus laevis | 1985 |
The mesencephalic locomotor region in cat: effects of local applications of diazepam and gamma-aminobutyric acid.
Topics: Animals; Cats; Cerebral Decortication; Diazepam; gamma-Aminobutyric Acid; Locomotion; Muscimol; Picrotoxin; Reaction Time; Reflex; Tegmentum Mesencephali | 1985 |
Chemical activation of the mesencephalic locomotor region.
Topics: Animals; Bicuculline; Brain Mapping; Cats; Efferent Pathways; Electric Stimulation; gamma-Aminobutyric Acid; Locomotion; Models, Neurological; Picrotoxin; Spinal Cord; Tegmentum Mesencephali | 1985 |
gamma-Amino butyric-N-acid sensitivity of mouse and human oocytes.
Topics: Animals; Bicuculline; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ions; Metaphase; Mice; Mice, Inbred Strains; Oocytes; Picrotoxin; Zygote | 1985 |
Effects of glycine and GABA on the ganglion cels of the retina of the skate Raja erinacea.
Topics: Animals; Bicuculline; Fishes; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Picrotoxin; Retina; Retinal Ganglion Cells | 1985 |
Respiratory depression produced by injection of GABA into the fourth ventricle of the rabbit.
Topics: Animals; Bicuculline; Depression, Chemical; Diazepam; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Picrotoxin; Rabbits; Respiration | 1985 |
Actions of GABA and ethylenediamine on CA1 pyramidal neurones of the rat hippocampus.
Topics: Animals; Benzodiazepines; Bicuculline; Chlorides; Dendrites; Electric Conductivity; Ethylenediamines; gamma-Aminobutyric Acid; Hippocampus; Ion Exchange; Neurons; Osmolar Concentration; Picrotoxin; Potassium; Rats; Sodium | 1985 |
Stability of the amino acid content of nerve endings after administration of gamma-aminobutyrate agonists and antagonists.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Baclofen; Bicuculline; Brain Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mice; Muscimol; Nerve Endings; Picrotoxin; Synaptosomes | 1985 |
Development of sensitivity to GABA and glycine in cultured cerebellar neurons.
Topics: Action Potentials; Animals; Bicuculline; Cell Membrane; Cerebellum; Chick Embryo; Culture Techniques; Electric Conductivity; gamma-Aminobutyric Acid; Glycine; Picrotoxin; Strychnine | 1985 |
gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells.
Topics: Animals; Benzodiazepines; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Muscimol; Picrotoxin; Rats; Sulfur Radioisotopes; Temperature | 1985 |
Electrophysiological evidence that the mediodorsal nucleus of the thalamus is a relay between the ventral pallidum and the medial prefrontal cortex in the rat.
Topics: Animals; Brain Mapping; Evoked Potentials; Frontal Lobe; gamma-Aminobutyric Acid; Globus Pallidus; Male; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Thalamic Nuclei | 1985 |
The role of the gamma-aminobutyrate system in the interactions of cortical evoked potentials.
Topics: Acoustic Stimulation; Animals; Baclofen; Bicuculline; Cats; Cerebral Cortex; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin | 1985 |
Studies of the role of gamma-aminobutyric acid in the hypothalamic control of feed intake in sheep.
Topics: Animals; Bicuculline; Brain; Eating; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep | 1985 |
Antagonism of picrotoxin against the taming effect of carbamazepine on footshock induced fighting behavior in mice.
Topics: Aggression; Animals; Bicuculline; Carbamazepine; Diazepam; Electroshock; gamma-Aminobutyric Acid; Haloperidol; Lithium; Male; Mice; Pentylenetetrazole; Picrotoxin | 1985 |
The action of picrotoxin on the interspike interval in rat supraoptic neurones.
Topics: Action Potentials; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Neurons; Picrotoxin; Rats; Reaction Time; Supraoptic Nucleus | 1985 |
Effects of avermectin B1a and picrotoxin on striatal release of dopamine with reference to replacement of extracellular chloride with nitrate.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Chlorides; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Male; Nitrates; Picrotoxin; Rats; Rats, Inbred Strains; Tetrodotoxin; Verapamil | 1985 |
Antagonists of the putative inhibitory transmitter effects of taurine and GABA in the retina.
Topics: Aminobutyrates; Animals; Chickens; Depression, Chemical; Electroretinography; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Neural Pathways; Picrotoxin; Retina; Strychnine; Superior Colliculi; Synaptic Transmission; Taurine; Time Factors | 1974 |
The influence of serotonin, GABA and DL-dopa on the circadian rhythm in the toxicity of picrotoxin, pentylenetetrazol and phenobarbital in mice.
Topics: Aminobutyrates; Animals; Circadian Rhythm; Dihydroxyphenylalanine; gamma-Aminobutyric Acid; Lethal Dose 50; Male; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Serotonin; Time Factors | 1974 |
Problems associated with iontophoretic studies in the caudate nucleus and substantia nigra.
Topics: Animals; Apomorphine; Behavior, Animal; Cats; Caudate Nucleus; Ergonovine; gamma-Aminobutyric Acid; Iontophoresis; Microelectrodes; Neurons; Picrotoxin; Rabbits; Substantia Nigra | 1974 |
A comparison of the effects of GABA and imidazoleacetic acid on the membrane conductance of lobster muscle fibres.
Topics: Acetates; Aminobutyrates; Animals; Cell Membrane; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; gamma-Aminobutyric Acid; Imidazoles; Muscles; Nephropidae; Picrotoxin; Receptors, Drug; Stimulation, Chemical | 1974 |
Depolarizing actions of gamma-aminobutyric acid and related compounds on rat superior cervical ganglia in vitro.
Topics: Alanine; Aminobutyrates; Aminoisobutyric Acids; Animals; Carbachol; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glutamine; Glycine; Hexamethonium Compounds; Hydroxybutyrates; Isoquinolines; Male; Membrane Potentials; Picrotoxin; Rats; Receptors, Cholinergic; Scopolamine; Strychnine; Sulfonic Acids; Sympathetic Nervous System; Taurine | 1974 |
Proceedings: Pharmacological studies on single neurones in the substantia nigra of the rat.
Topics: Acetates; Acetylcholine; Animals; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glycine; Imidazoles; Iontophoresis; Neurons; Norepinephrine; Picrotoxin; Rats; Serotonin; Strychnine; Substantia Nigra | 1974 |
Effects of gamma-aminobutyric acid (GABA) and GABA antagonist drugs on ACTH release.
Topics: Adrenocorticotropic Hormone; Alkaloids; Aminobutyrates; Animals; Corticosterone; Dioxoles; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hypothalamus; Interneurons; Isoquinolines; Male; Neural Pathways; Neurons, Afferent; Neurotransmitter Agents; Picrotoxin; Pituitary Gland; Pituitary Gland, Anterior; Proline; Rats; Sodium Chloride; Stimulation, Chemical; Synaptic Transmission | 1974 |
The ionic mechanism of action of GABA and L-glutamate on a crustacean striated muscle (vas deferens of the crayfish).
Topics: Aminobutyrates; Animals; Astacoidea; Chlorides; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Lithium; Male; Muscle Contraction; Muscles; Picrotoxin; Receptors, Drug; Sodium; Vas Deferens | 1974 |
[Microiontophoretical application of GABA and L-glutamic-acid on neurons of the mammalian C.N.S (author's transl)].
Topics: Aminobutyrates; Animals; Bicuculline; Cats; Caudate Nucleus; Central Nervous System; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Neurons; Picrotoxin; Spinal Cord; Tetrodotoxin | 1974 |
Is gamma-aminobutyric acid the neurotransmitter of barnacle photoreceptors?
Topics: Animals; Bicuculline; Cell Membrane; gamma-Aminobutyric Acid; In Vitro Techniques; Photoreceptor Cells; Picrotoxin; Synaptic Membranes; Synaptic Transmission; Thoracica; Vision, Ocular | 1984 |
Pharmacology of the isolated semicircular canal: effect of GABA and picrotoxin.
Topics: Animals; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Rana catesbeiana; Semicircular Canals; Synaptic Transmission; Vestibular Nerve | 1984 |
Avermectin modulation of GABA binding to membranes of rat brain, brine shrimp and a fungus, Mucor miehei.
Topics: Animals; Bicuculline; Brain; Chlorides; Decapoda; gamma-Aminobutyric Acid; Ivermectin; Kinetics; Lactones; Male; Mucor; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sodium | 1984 |
Influence of GABA on the spectral and spatial coding of goldfish retinal ganglion cells.
Topics: Animals; Color Perception; Culture Techniques; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Goldfish; Photic Stimulation; Picrotoxin; Retina; Retinal Ganglion Cells; Space Perception; Synaptic Transmission; Visual Fields | 1984 |
Synchronized afterdischarges in the hippocampus: contribution of local synaptic interactions.
Topics: Action Potentials; Animals; Brain Mapping; Calcium; Electrophysiology; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Periodicity; Picrotoxin; Synapses; Synaptic Transmission | 1984 |
GABAergic influence on the effects of elymoclavine on exploratory behaviour of rats in open field.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Ergolines; Exploratory Behavior; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Semicarbazides | 1984 |
GABA receptors mediate cerebral vasodilation in the unanesthetized goat.
Topics: Animals; Atropine; Blood Pressure; Brain; Female; gamma-Aminobutyric Acid; Goats; Muscimol; Picrotoxin; Receptors, GABA-A; Vascular Resistance; Vasodilation | 1984 |
Effect of gamma-aminobutyric acid on cyclic nucleotides content of guinea-pig cerebral cortex slices.
Topics: Adenosine; alpha-Methyltyrosine; Animals; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Methyltyrosines; Neurons; Norepinephrine; Phentolamine; Picrotoxin; Reserpine; Theophylline | 1984 |
[Effect of picrotoxin on the receptive fields of neurons of the vibrissal projection area in the cerebral cortex of the cat].
Topics: Animals; Cats; Face; gamma-Aminobutyric Acid; Hair; Neural Inhibition; Picrotoxin; Sense Organs; Somatosensory Cortex; Synaptic Transmission | 1984 |
The action of gamma-aminobutyric acid (GABA) and ethylenediamine (EDA) on Limulus and Helix central neurones and rat cerebellar and sympathetic ganglion neurones.
Topics: Animals; Cerebellum; Ethylenediamines; Female; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Helix, Snails; Horseshoe Crabs; Neurons; Picrotoxin; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sesterterpenes | 1984 |
Effects of a neurotoxin in hornet venom on neuromuscular junctions of lobster.
Topics: 4-Aminobutyrate Transaminase; Animals; Bee Venoms; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Nephropidae; Neuromuscular Junction; Neurotoxins; Picrotoxin; Synaptic Membranes; Wasps | 1980 |
Some barbiturates enhance the effect of muscimol on dopamine turnover in the rat retina.
Topics: Animals; Barbital; Barbiturates; Convulsants; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Light; Male; Methyltyrosines; Muscimol; Oxazoles; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Retina; Sesterterpenes | 1980 |
Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Diazepam; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stress, Physiological; Thiosemicarbazones | 1980 |
A GABAergic influence on the light-induced increase in dopamine turnover in the dark-adapted rat retina in vivo.
Topics: Animals; Dark Adaptation; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Light; Male; Methyltyrosines; Muscimol; Picrotoxin; Rats; Retina; Tyrosine 3-Monooxygenase | 1980 |
[Selective suppression of retinal oscillatory potential by some omega-amino acids and its release by their antagonists in human and rabbit in-vitro (author's transl)].
Topics: Alanine; Amino Acids; Animals; Electroretinography; gamma-Aminobutyric Acid; Glycine; Humans; In Vitro Techniques; Neurotransmitter Agents; Picrotoxin; Rabbits; Retina; Strychnine; Taurine | 1980 |
Localization of sensitive sites to taurine, gamma-aminobutyric acid, glycine and beta-alanine in the molecular layer of guinea-pig cerebellar slices.
Topics: Amino Acids; Animals; beta-Alanine; Binding Sites; Cerebellum; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Male; Neurons; Neurotransmitter Agents; Picrotoxin; Strychnine; Taurine | 1980 |
Avoidance enhancement and discriminative response control by anxiolytics with drugs acting on the GABA system.
Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Avoidance Learning; Discrimination Learning; Drug Synergism; gamma-Aminobutyric Acid; Male; Methyltyrosines; Mice; Picrotoxin; Rats; Semicarbazides; Spiperone | 1980 |
Modulation by picrotoxin and IPTBO of 3H-flunitrazepam binding to the GABA/benzodiazepine receptor complex of rat cerebellum.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Binding Sites; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cerebellum; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; Male; Membranes; Organophosphorus Compounds; Picrotoxin; Rats; Receptors, Drug; Receptors, GABA-A; Temperature | 1981 |
The role of GABA in the regulation of the dopamine/tyrosine hydroxylase-containing neurons of the rat retina.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neurons; Photic Stimulation; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1981 |
Dihydropicrotoxinin binding sites in mammalian brain: interaction with convulsant and depressant benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Seizures; Stereoisomerism | 1981 |
Effect of GABAergic drugs on dopamine catabolism in the nigrostriatal and mesolimbic dopaminergic pathways of the rat.
Topics: 4-Aminobutyrate Transaminase; Animals; Corpus Striatum; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Limbic System; Male; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA-A; Substantia Nigra | 1981 |
Iontophoretic studies on pallidal neurones and the projection from the subthalamic nucleus.
Topics: Animals; Dopamine; Fluphenazine; gamma-Aminobutyric Acid; Globus Pallidus; Glycine; Iontophoresis; Male; Mesencephalon; Naloxone; Neural Pathways; Neurons; Neurotransmitter Agents; Picrotoxin; Rats; Strychnine; Thalamic Nuclei | 1981 |
Septal driving of hippocampal theta rhythm: a role for gamma-aminobutyrate in the effects of minor tranquillizers?
Topics: Amobarbital; Animals; Anti-Anxiety Agents; Bicuculline; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Antagonism; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Picrotoxin; Rats; Septum Pellucidum | 1981 |
[Effect of GABA-negative preparations on the anxiolytic and sedative effects of diazepam].
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Picrotoxin; Rats | 1981 |
Behavior during hippocampal microinfusions. IV. Transmitter interactions.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Exploratory Behavior; gamma-Aminobutyric Acid; Hippocampus; Male; Motor Activity; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1982 |
The effects of anaesthetics on the uptake and release of amino acid neurotransmitters in thalamic slices.
Topics: Anesthetics; Animals; Aspartic Acid; Baclofen; Bicuculline; Calcium; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Methohexital; Neurotransmitter Agents; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Thalamus | 1982 |
Benzodiazepines: from receptor to function in sleep.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Humans; Ion Channels; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Sleep Stages | 1982 |
Anion-dependent modulation of [3H]muscimol binding and of GABA-stimulated [3H]flunitrazepam binding by picrotoxin and related CNS convulsants.
Topics: Animals; Anions; Anti-Anxiety Agents; Cerebral Cortex; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Oxazoles; Picrotoxin; Rats; Receptors, Drug; Receptors, GABA-A; Strychnine; Tubocurarine | 1982 |
Gabamimetic properties of anxiolytic drugs.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Caudate Nucleus; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Male; Movement; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Specificity of GABA as a stimulator of dopamine release in rat substantia nigra.
Topics: Amino Acids; Animals; Dopamine; Flurazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Sodium; Structure-Activity Relationship; Substantia Nigra | 1980 |
The interactions of ethanol with the benzodiazepine-GABA receptor-ionophore complex.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Ethanol; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptic Membranes; Synaptic Transmission | 1983 |
omega-Aminosulfonic acids as depressant or excitant compounds: their effect on the behavior and electroencephalogram of young chickens.
Topics: Alkanesulfonates; Alkanesulfonic Acids; Animals; Behavior, Animal; Central Nervous System Depressants; Central Nervous System Stimulants; Chickens; Electroencephalography; gamma-Aminobutyric Acid; Pentylenetetrazole; Picrotoxin; Structure-Activity Relationship; Strychnine; Taurine; Tubocurarine | 1983 |
GABAB receptor mediated inhibition of field stimulation-induced contractions of rabbit bladder muscle in-vitro.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Atropine; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Picrotoxin; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1984 |
Rat hippocampal neurons in culture: voltage-clamp analysis of inhibitory synaptic connections.
Topics: Animals; Chlorides; Culture Techniques; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Ion Channels; Kinetics; Membrane Potentials; Neural Inhibition; Neurons; Pentobarbital; Picrotoxin; Rats; Reaction Time; Synapses | 1984 |
Electrophysiological evidence for the existence of excitatory fibres in the caudato-nigral pathway in the cat.
Topics: Animals; Atropine; Baclofen; Cats; Caudate Nucleus; Electrophysiology; gamma-Aminobutyric Acid; Neural Pathways; Picrotoxin; Reaction Time; Substance P; Substantia Nigra | 1980 |
In vivo evidence for GABAergic control of serotonin release in the cat substantia nigra.
Topics: Animals; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Serotonin; Substance P; Substantia Nigra; Tritium | 1981 |
Inhibitory effects of GABA, L-glutamic acid and nicotine on the potassium-evoked release of substance P in substantia nigra slices of the rat.
Topics: Animals; Calcium; gamma-Aminobutyric Acid; Glutamates; Immune Sera; In Vitro Techniques; Male; Nicotine; Picrotoxin; Potassium; Rats; Receptors, Nicotinic; Substance P; Substantia Nigra; Tetrodotoxin | 1981 |
Evidence for similarities between cyclodiene type insecticides and picrotoxinin in their action mechanisms.
Topics: Animals; Binding, Competitive; Chlorides; Cockroaches; Drug Resistance; gamma-Aminobutyric Acid; Heptachlor; Heptachlor Epoxide; Hexachlorocyclohexane; Male; Muscles; Periplaneta; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptosomes | 1983 |
GABAB receptor-mediated inhibition of serotonin release in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Brain Chemistry; Cerebral Cortex; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Nipecotic Acids; Phentolamine; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Serotonin | 1984 |
Glycine-and gaba-ergic elements in the development of embryonic spontaneous motility.
Topics: Animals; Brain; Chick Embryo; gamma-Aminobutyric Acid; Glycine; Motor Activity; Picrotoxin; Strychnine | 1982 |
Bicyclic phosphates increase the cyclic GMP level in rat cerebellum, presumably due to reduced GABA inhibition.
Topics: Animals; Cerebellum; Cyclic GMP; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Nerve Fibers; Phosphates; Picrotoxin; Pyridines; Rats; Receptors, Neurotransmitter; Synaptosomes | 1980 |
Picrotoxin block of a depolarizing ACh response.
Topics: Acetylcholine; Animals; Brachyura; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Neuromuscular Junction; Picrotoxin; Sodium; Synapses; Synaptic Transmission | 1980 |
GABA and picrotoxinin receptors in clonal nerve cells.
Topics: Animals; Brain; Cell Line; Clone Cells; gamma-Aminobutyric Acid; Kinetics; Neuroglia; Picrotoxin; Rats; Receptors, Neurotransmitter | 1980 |
Modulation by GABA of cholinergic transmission in the striatum.
Topics: Acetylcholine; Animals; Cholinergic Fibers; Corpus Striatum; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Picrotoxin; Rats; Synaptic Transmission | 1980 |
Inhibition of transmitter release in bullfrog sympathetic ganglia induced by gamma-aminobutyric acid.
Topics: Acetylcholine; Action Potentials; Animals; Anura; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Sympathetic; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Picrotoxin; Potassium; Rana catesbeiana; Synapses; Synaptic Transmission | 1980 |
A site for the potentiation of GABA-mediated responses by benzodiazepines.
Topics: Afferent Pathways; Animals; Bicuculline; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Ion Channels; Medulla Oblongata; Membrane Potentials; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
The effects of pentobarbital and related compounds on frog motoneurons.
Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission | 1980 |
A specific effect of morphine on evoked activity in the rat hippocampal slice.
Topics: Animals; Culture Techniques; Dendrites; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Male; Morphine; Neurons; Picrotoxin; Rats; Synapses; Synaptic Transmission | 1980 |
Inhibitory action of ibotenic acid on the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ibotenic Acid; Membrane Potentials; Neural Inhibition; Neuromuscular Junction; Oxazoles; Picrotoxin; Receptors, Neurotransmitter | 1980 |
Pharmacological dissection of pyloric network of the lobster stomatogastric ganglion using picrotoxin.
Topics: Acetylcholine; Animals; gamma-Aminobutyric Acid; Ganglia; Glutamates; In Vitro Techniques; Nephropidae; Picrotoxin; Synapses; Synaptic Transmission | 1980 |
Effect of picrotoxin on benzodiazepine receptors and GABA receptors with reference to the effect of C1- ion.
Topics: Animals; Cerebellum; Chlorides; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Intracellular Membranes; Male; Models, Biological; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptosomes | 1981 |
GABA and muscimol inhibit the release of prolactin from dispersed rat anterior pituitary cells.
Topics: Animals; Bicuculline; Dopamine; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Injections of dopaminergic, cholinergic, serotoninergic and GABAergic drugs into the nucleus accumbens: effects on locomotor activity in the rat.
Topics: Animals; Atropine; Carbachol; Dopamine; gamma-Aminobutyric Acid; Male; Methysergide; Motor Activity; Nucleus Accumbens; Picrotoxin; Rats; Receptors, Cell Surface; Septal Nuclei; Serotonin | 1981 |
Microiontophoretic study of the GABA receptor in the feline caudate nucleus.
Topics: Animals; Cats; Caudate Nucleus; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
GABA and baclofen potentiate the K+-evoked release of methionine-enkephalin from rat striatal slices.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Corpus Striatum; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Picrotoxin; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Voltage clamp analysis of inhibitory synaptic action in crayfish stretch receptor neurons.
Topics: Animals; Astacoidea; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channels; Mechanoreceptors; Membrane Potentials; Neural Inhibition; Phenytoin; Picrotoxin; Synapses | 1981 |
[Effect of neutral amino acids on neurons and synaptic transmission in the isolated rat spinal cord].
Topics: Amino Acids; Animals; beta-Alanine; gamma-Aminobutyric Acid; Glycine; Motor Neurons; Neurons, Afferent; Picrotoxin; Rats; Spinal Cord; Strychnine; Synaptic Transmission | 1981 |
Interactions between cholinergic drugs, gamma-aminobutyric acid and cyclic guanosine monophosphate on picrotoxin-induced convulsive-seizure threshold.
Topics: Animals; Cyclic GMP; Dibutyryl Cyclic GMP; Drug Interactions; gamma-Aminobutyric Acid; Mice; Oxotremorine; Parasympathomimetics; Picrotoxin; Seizures | 1981 |
Pentobarbitone interference with inhibitory synaptic transmission in crayfish stretch receptor neurones.
Topics: Animals; Astacoidea; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Neural Inhibition; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1981 |
Pharmacologic analysis of sodium valproate-induced suppression of secondary components of visual evoked potentials in albino rats.
Topics: Animals; Benzodiazepinones; Convulsants; Drug Interactions; Evoked Potentials, Visual; Female; gamma-Aminobutyric Acid; Male; Naloxone; Pentylenetetrazole; Photic Stimulation; Picrotoxin; Rats; Synaptic Transmission; Time Factors; Valproic Acid | 1981 |
Gaba induced excitatory responses in the guinea-pig small intestine are antagonized by bicuculline, picrotoxinin and chloride ion blockers.
Topics: Animals; Bicuculline; Chlorides; Diuretics; Female; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Myenteric Plexus; Picrotoxin; Sesterterpenes; Sulfonamides | 1981 |
Gnawing and changes in reactivity produced by microinjections of picrotoxin into the superior colliculus of rats.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; Picrotoxin; Rats; Stereotyped Behavior; Superior Colliculi; Synaptic Transmission | 1981 |
Collicular picrotoxin alleviates akinesia but not sensory neglect in rats with bilateral 6-hydroxydopamine lesions of ventral midbrain.
Topics: Animals; Apomorphine; GABA Antagonists; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Mesencephalon; Motor Activity; Oxidopamine; Picrotoxin; Rats; Sensation; Superior Colliculi; Synaptic Transmission | 1981 |
Specific proconvulsant action of an imidazobenzodiazepine (RO 15-1788) on isoniazid convulsions.
Topics: Animals; Benzodiazepinones; Brain; Convulsants; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; Isoniazid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures | 1982 |
Effect of synaptic transmitter drugs on receptive fields of rabbit retinal ganglion cells.
Topics: Acetylcholine; Animals; gamma-Aminobutyric Acid; Glycine; Mecamylamine; Neurons; Physostigmine; Picrotoxin; Rabbits; Retina; Strychnine; Synaptic Transmission | 1981 |
A comparative study of avermectin B1a and other modulators of the gamma-aminobutyric acid receptor . chloride ion channel complex.
Topics: Animals; Anthelmintics; Benzodiazepines; Brain; Chlorides; Clonazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Male; Pentobarbital; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptic Membranes | 1982 |
Nigral output neurons are engaged in regulation of static fusimotor action onto flexors in cat.
Topics: Animals; Cats; gamma-Aminobutyric Acid; Motor Neurons; Motor Neurons, Gamma; Muscimol; Muscle Contraction; Muscle Spindles; Neurons, Afferent; Picrotoxin; Receptors, Neurotransmitter; Substantia Nigra | 1981 |
Antagonism of GABA-mediated responses by d-tubocurarine in hippocampal neurons.
Topics: Animals; Bicuculline; Culture Techniques; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Neural Inhibition; Neurons; Picrotoxin; Receptors, Adrenergic, beta; Seizures; Synapses; Synaptic Transmission; Tetrodotoxin; Tubocurarine | 1982 |
Sodium valproate enhances responses to GABA receptor activation only at high concentrations.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution; Valproic Acid | 1982 |
Convulsant and anticonvulsant effects of opioids: relationship to GABA-mediated transmission.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Brain; Convulsants; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Morphine; Naloxone; Narcotics; Picrotoxin; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1982 |
Anisatin modulation of GABA- and pentobarbital-induced enhancement of diazepam binding in rat brain.
Topics: Animals; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lactones; Male; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Sesquiterpenes; Sesterterpenes; Spiro Compounds | 1982 |
Further characterization of the anorexic action of orally-administered THIP, a GABA-analogue, in the rat.
Topics: Administration, Oral; Animals; Bicuculline; Eating; gamma-Aminobutyric Acid; Isoxazoles; Male; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Strychnine | 1982 |
Substantia nigra as a station that not only transmits, but also transforms, incoming signals for its behavioural expression: striatal dopamine and GABA-mediated responses of pars reticulata neurons.
Topics: Animals; Apomorphine; Behavior, Animal; Cats; Caudate Nucleus; Corpus Striatum; Dominance, Cerebral; Dopamine; Female; gamma-Aminobutyric Acid; Haloperidol; Hindlimb; Humans; Male; Motor Activity; Muscimol; Neural Pathways; Picrotoxin; Stereotyped Behavior; Substantia Nigra; Synaptic Transmission | 1983 |
Presence of GABA receptors in rat oviduct.
Topics: Animals; Bicuculline; Binding, Competitive; Cyclic AMP; Fallopian Tubes; Female; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Enhancement of GABA binding by pentobarbitone.
Topics: Animals; Brain; Cell Membrane; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptosomes | 1980 |
Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments.
Topics: 3-Mercaptopropionic Acid; Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Brain; Cell Compartmentation; Cell Fractionation; Cerebellum; Drug Interactions; Female; gamma-Aminobutyric Acid; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Synaptosomes | 1983 |
gamma-Aminobutyric acid and cholinergic transmission in the guinea-pig ileum.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Synaptic Transmission; Tritium | 1983 |
Pyrethroids of the most potent class antagonize GABA action at the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; Clonazepam; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Junction; Picrotoxin; Pyrethrins; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptic Transmission | 1983 |
Central gamma-aminobutyric acid involvement in blood pressure control.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Hypertension; Medulla Oblongata; Pentobarbital; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Respiration | 1984 |
GABA modulation of the defense reaction induced by brain electrical stimulation.
Topics: Animals; Benzodiazepines; Bicuculline; Blood Pressure; Chlordiazepoxide; Electric Stimulation; Escape Reaction; gamma-Aminobutyric Acid; Heart Rate; Male; Midazolam; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Respiration | 1983 |
Saturable binding of 35S-t-butylbicyclophosphorothionate to the sites linked to the GABA receptor and the interaction with GABAergic agents.
Topics: Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sulfur Radioisotopes; Triazines | 1984 |
Excitatory and inhibitory effects of noradrenaline on synaptic transmission in the rat olfactory cortex slice.
Topics: Adenosine; Animals; Central Nervous System; Cerebral Cortex; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Norepinephrine; Olfactory Pathways; Picrotoxin; Potassium; Rats; Synapses; Synaptic Transmission | 1984 |
Effects of ethosuximide and tetramethylsuccinimide on cultured cortical neurons.
Topics: Animals; Anticonvulsants; Ethosuximide; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Junction; Picrotoxin; Receptors, Neurotransmitter; Rodentia; Succinimides; Synaptic Transmission | 1984 |
Acute and delayed effects of picrotoxin on the adrenocorticotropic system of rats.
Topics: Adrenocorticotropic Hormone; Animals; Circadian Rhythm; Corticosterone; Female; gamma-Aminobutyric Acid; Picrotoxin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Serotonin | 1983 |
GABA antagonists applied to the ventral surface of the medulla oblongata block the baroreceptor reflex.
Topics: Animals; Bicuculline; Blood Pressure; Brain Mapping; Cats; gamma-Aminobutyric Acid; Medulla Oblongata; Picrotoxin; Pressoreceptors; Reflex; Synaptic Transmission; Vasomotor System | 1984 |
Evidence for the involvement of brain GABA and serotonin systems in the anticonflict effects of chlordiazepoxide in rats.
Topics: Animals; Brain; Chlordiazepoxide; Conflict, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Ethanolamines; gamma-Aminobutyric Acid; Indoles; Male; Picrotoxin; Rats; Serotonin; Synaptic Transmission; Time Factors | 1984 |
Fastigial influences on postural tonus as studied by kainate lesions and by local infusion of GABAergic drugs in the rat.
Topics: Animals; Bicuculline; Cerebellar Nuclei; Diazepam; Functional Laterality; gamma-Aminobutyric Acid; Kainic Acid; Male; Motor Activity; Muscle Tonus; Picrotoxin; Posture; Pyrrolidines; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1984 |
The striato-nigro-collicular pathway and explosive running behaviour: functional interaction between neostriatal dopamine and collicular GABA.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Male; Microinjections; Picrotoxin; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Substantia Nigra; Superior Colliculi | 1984 |
Effect of apomorphine and gabaergic drugs in monkeys pretreated with haloperidol.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Apomorphine; Chlorocebus aethiops; Female; gamma-Aminobutyric Acid; Haloperidol; Hemodynamics; Isoxazoles; Male; Motor Activity; Muscimol; Picrotoxin | 1983 |
Stereostructure-activity relationships of the GABA-containing cis-decahydroquinoline-5-carboxylic acids; intracerebroventricular studies in mice.
Topics: Animals; Apomorphine; Behavior, Animal; Convulsants; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Picrotoxin; Quinolines; Stereoisomerism; Structure-Activity Relationship; Valproic Acid | 1983 |
Effect of dihydroergotoxine on the susceptibility of rats to convulsions produced by different convulsant agents.
Topics: Animals; Bicuculline; Convulsants; Dihydroergotoxine; Drug Synergism; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Strychnine | 1983 |
Facilitation of diazepam action by anticonvulsant agents against picrotoxin induced convulsions.
Topics: Animals; Anticonvulsants; Diazepam; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1983 |
Gabaergic modulation of mouse-killing in the rat.
Topics: Aggression; Aminocaproates; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Motor Activity; Nipecotic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Valproic Acid; Vigabatrin | 1984 |
Effect of intrastriatal administration of cholinergic and GABAergic agonists on apomorphine-induced circling.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Drug Interactions; gamma-Aminobutyric Acid; Humans; Injections; Male; Muscimol; Parasympathomimetics; Picrotoxin; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Scopolamine; Stereotyped Behavior | 1984 |
Chlordiazepoxide-induced hyperphagia in rats: lack of effect of GABA agonists and antagonists.
Topics: Animals; Chlordiazepoxide; Eating; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1984 |
An analysis of the cortical and striatal involvement in dyskinesia induced in rats by intracerebral injection of GABA-transaminase inhibitors and picrotoxin.
Topics: 4-Aminobutyrate Transaminase; Administration, Topical; Animals; Brain; Cerebral Cortex; Corpus Striatum; Diffusion; Disease Models, Animal; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Huntington Disease; Injections; Male; Picrotoxin; Rats; Transaminases | 1980 |
[Influence of the GABAergic system on eating behavior induced by the tail pinching technic in rats].
Topics: Animals; Energy Intake; Feeding Behavior; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Oxazoles; Picrotoxin; Rats; Rats, Inbred Strains; Stress, Psychological; Valproic Acid | 1981 |
Gamma-aminobutyric acid-induced contraction of the dog basilar artery.
Topics: Animals; Arachidonic Acids; Aspirin; Basilar Artery; Bicuculline; Dogs; Drug Interactions; Ethanol; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Indomethacin; Leukotrienes; Lipid Peroxides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Picrotoxin | 1984 |
Blockade of central nervous system GABAergic tone causes sympathetic-mediated increases in coronary vascular resistance in cats.
Topics: Animals; Cats; Central Nervous System; Coronary Vessels; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hemodynamics; Lactates; Male; Myocardium; Phentolamine; Picrotoxin; Sympathectomy; Vascular Resistance; Vasopressins | 1984 |
The nature of the stimulatory action of gamma-aminobutyric acid in the isolated perfused dog adrenals.
Topics: Acetylcholine; Adrenal Glands; Animals; Atropine; Bicuculline; Calcium; Catecholamines; Cobalt; Dibucaine; Dogs; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Male; Picrotoxin; Tetrodotoxin; Verapamil | 1984 |
The actions of gamma-aminobutyric acid, glycine and their antagonists upon horizontal cells of the Xenopus retina.
Topics: Action Potentials; Animals; Dark Adaptation; Feedback; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Membrane Potentials; Neurons; Photic Stimulation; Picrotoxin; Retina; Strychnine; Xenopus laevis | 1984 |
Strychnine blocks transient but not sustained inhibition in mudpuppy retinal ganglion cells.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Membrane Potentials; Necturus; Neural Inhibition; Picrotoxin; Retina; Retinal Ganglion Cells; Strychnine | 1984 |
Prolactin and growth hormone secretion in chickens: stimulation by histamine and inhibition by gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Cells, Cultured; Chickens; Culture Media; Diphenhydramine; gamma-Aminobutyric Acid; Growth Hormone; Histamine; Hypothalamus; Picrotoxin; Pituitary Gland, Anterior; Prolactin | 1984 |
Alkyl-substituted gamma-butyrolactones inhibit [35S]TBPS binding to a GABA linked chloride ionophore.
Topics: 4-Butyrolactone; Animals; Barbiturates; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chlorides; Furans; gamma-Aminobutyric Acid; In Vitro Techniques; Ionophores; Male; Membranes; Picrotoxin; Rats; Rats, Inbred Strains | 1984 |
Evidence for a physiological role of GABA in the control of guinea-pig intestinal motility.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle, Smooth; Myenteric Plexus; Picrotoxin; Sesterterpenes; Tachyphylaxis | 1984 |
Inhibitory modulation of cat somatosensory cortex: a pharmacological study.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cats; Evoked Potentials; Evoked Potentials, Somatosensory; Female; gamma-Aminobutyric Acid; Neural Inhibition; Picrotoxin; Somatosensory Cortex; Taurine | 1984 |
Effects of intraventricular injections of gamma-aminobutyric acid and related substances on feeding behavior in satiated sheep.
Topics: Animals; Drug Interactions; Feeding Behavior; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Muscimol; Picrotoxin; Satiation; Sheep | 1984 |
The actions of barbiturates on release of noradrenaline from rat hippocampal synaptosomes.
Topics: Animals; Barbiturates; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Synaptosomes | 1984 |
A GABAergic habenulo-raphe pathway mediates both serotoninergic and hypnogenic effects of vasotocin in cats.
Topics: Animals; Arginine Vasopressin; Brain Mapping; Cats; Diencephalon; gamma-Aminobutyric Acid; Male; Neural Pathways; Picrotoxin; Raphe Nuclei; Serotonin; Sleep; Sleep Stages | 1984 |
The role of the GABA mechanisms of the globus pallidus in mediating catalepsy, stereotypy and locomotor activity.
Topics: Animals; Bicuculline; Brain Mapping; Catalepsy; Drug Interactions; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1984 |
Anticonvulsant activity of the nipecotic acid ester, (+/-)-m-nitrophenyl-3-piperidinecarboxylate.
Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Nipecotic Acids; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1984 |
Behavioural and biochemical studies with the benzamide sulpiride in rats.
Topics: Animals; Apomorphine; Brain; Dialysis; Ergolines; Flupenthixol; gamma-Aminobutyric Acid; Glutamates; Motor Activity; Pergolide; Picrotoxin; Rats; Receptors, Dopamine; Rotation; Scopolamine; Sulpiride | 1984 |
Involvement of GABAergic mechanisms in the optokinetic nystagmus of the frog.
Topics: Animals; Brain Mapping; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Neural Inhibition; Nystagmus, Physiologic; Picrotoxin; Rana temporaria | 1983 |
Inhibitory mechanism in zebrafish optic tectum: visual response properties of tectal cells altered by picrotoxin and bicuculline.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials, Visual; Fishes; gamma-Aminobutyric Acid; Neural Inhibition; Optic Nerve; Pattern Recognition, Visual; Picrotoxin; Strychnine; Superior Colliculi; Synapses; Visual Pathways; Visual Perception | 1983 |
A short duration GABAergic inhibition in identified neostriatal medium spiny neurons: in vitro slice study.
Topics: Animals; Bicuculline; Corpus Striatum; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons; Penicillin G; Picrotoxin; Rats; Synapses | 1983 |
Involvement of GABA in palate morphogenesis and its relation to diazepam teratogenesis in two mouse strains.
Topics: Animals; Cells, Cultured; Diazepam; Female; gamma-Aminobutyric Acid; Mice; Palate; Picrotoxin; Pregnancy; Species Specificity; Teratogens | 1983 |
Inhibition of drug-induced circling by GABA-ergic activity in the nucleus accumbens.
Topics: Animals; Brain Mapping; Dextroamphetamine; gamma-Aminobutyric Acid; Limbic System; Male; Muscimol; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei | 1983 |
Generation of respiratory activity by the lamprey brain exposed to picrotoxin and strychnine, and weak synaptic inhibition in motoneurons.
Topics: Animals; Bicuculline; Brain; Fishes; gamma-Aminobutyric Acid; Glycine; Lampreys; Motor Neurons; Neural Inhibition; Neurons; Periodicity; Picrotoxin; Respiration; Respiratory System; Strychnine; Synapses | 1983 |
A GABAergic habenulo-raphe pathway mediation of the hypnogenic effects of vasotocin in cat.
Topics: Animals; Brain Stem; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Neural Pathways; Picrotoxin; Raphe Nuclei; Sleep; Sleep, REM; Thalamus; Vasotocin | 1983 |
Analyses of neural mechanisms mediating the effect of horizontal cell polarization.
Topics: Animals; Carps; Color Perception; Dark Adaptation; Feedback; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons; Photic Stimulation; Photoreceptor Cells; Picrotoxin; Retina | 1983 |
GABA-mediated inhibition of breathing in the late gestation sheep fetus.
Topics: Animals; Apnea; Female; Fetal Hypoxia; Fetus; gamma-Aminobutyric Acid; Gestational Age; Muscimol; Oxazoles; Picrotoxin; Pregnancy; Respiration; Sheep | 1983 |
Effect of phenoxybenzamine on the GABA system and on convulsive activity.
Topics: Aminooxyacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Phenoxybenzamine; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Tissue Distribution | 1983 |
A role for 5-hydroxytryptamine in the GABA-mimetic potentiation of alpha-flupenthixol-induced catalepsy in the rat.
Topics: Aminobutyrates; Animals; Catalepsy; Clomipramine; Clonazepam; Female; Flupenthixol; gamma-Aminobutyric Acid; Humans; Methysergide; Picrotoxin; Rats; Rats, Inbred Strains; Serotonin; Thioxanthenes | 1983 |
Binding characteristics and interactions of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Convulsants; Diazepam; Etomidate; gamma-Aminobutyric Acid; Male; Membranes; Pentobarbital; Picrotoxin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Sesterterpenes | 1984 |
Interactions of two phenylquinolines with picrotoxin and benzodiazepines in vivo and in vitro.
Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Myoclonus; Pentylenetetrazole; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Seizures | 1984 |
Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in vitro.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Growth Hormone; In Vitro Techniques; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1984 |
Pharmacological profile of wet-dog shaking induced by electrical stimulation of the fornix in rats.
Topics: Adenosine; Aminooxyacetic Acid; Animals; Atropine; Behavior, Animal; Dopamine; Electric Stimulation; Electrodes, Implanted; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Limbic System; Naloxone; Naltrexone; Neural Pathways; Physostigmine; Picrotoxin; Propranolol; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Actions of gamma-aminobutyric acid on neurones of guinea-pig myenteric plexus.
Topics: Acetylcholine; Alanine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Myenteric Plexus; Neural Conduction; Neuromuscular Depolarizing Agents; Neurons; Nipecotic Acids; Picrotoxin; Proline; Tetrodotoxin | 1984 |
The identification and some functions of GABAergic neurons in the distal catfish retina.
Topics: Adaptation, Ocular; Animals; Bicuculline; Fishes; gamma-Aminobutyric Acid; Neurons; Photoreceptor Cells; Picrotoxin; Potassium; Retina | 1984 |
Amino acid antagonists do not block the depolarizing effects of potassium ions on frog primary afferents.
Topics: Animals; Anura; beta-Alanine; Bicuculline; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neurons, Afferent; Picrotoxin; Potassium; Rana pipiens; Strychnine | 1980 |
Motor depression and head twitches induced by IP injection of GABA.
Topics: Animals; Cyproheptadine; Drug Interactions; gamma-Aminobutyric Acid; Humans; Injections, Intraperitoneal; Male; Mice; Morphine; Motor Activity; Picrotoxin; Rabbits; Rats; Serotonin; Stereotyped Behavior | 1980 |
Di-n-propylacetate-induced abstinence behaviour as a possible correlate of increased GABA-ergic activity in the rat.
Topics: 3-Mercaptopropionic Acid; Aminooxyacetic Acid; Animals; Behavior, Animal; Catalepsy; gamma-Aminobutyric Acid; Humans; Male; Picrotoxin; Rats; Strychnine; Substance Withdrawal Syndrome; Thiosemicarbazones; Valproic Acid | 1980 |
GABA conductance of chick spinal cord and dorsal root ganglion neurons in cell culture.
Topics: Amino Acids; Animals; beta-Alanine; Bicuculline; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Iontophoresis; Neurons; Picrotoxin; Spinal Cord; Strychnine; Taurine | 1981 |
Involvement of the GABAergic system on shock-induced aggressive behavior in two strains of mice.
Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Muscimol; Picrotoxin; Stimulation, Chemical; Valproic Acid | 1981 |
Anticonvulsant and antiaggressive properties of di-n-propyl acetate after repeated treatment.
Topics: Acoustic Stimulation; Aggression; Animals; Anticonvulsants; Brain; Female; gamma-Aminobutyric Acid; Humans; Male; Mice; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1982 |
GABAergic mechanisms within the ventral tegmental area: involvement of dopaminergic (A 10) and non-dopaminergic neurones.
Topics: Animals; Behavior, Animal; Brain; Dopamine; Ethanolamines; gamma-Aminobutyric Acid; Male; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Tegmentum Mesencephali; Time Factors | 1982 |
Ionic mechanisms of neutral amino acids and 5-hydroxytryptamine presynaptic inhibition in the spinal afferents.
Topics: Action Potentials; Amino Acids; Animals; beta-Alanine; Drug Interactions; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Neurons, Afferent; Picrotoxin; Rats; Serotonin; Spinal Cord; Spinal Nerve Roots | 1982 |
GABAergic influences on defensive fighting in rats.
Topics: Aggression; Aminocaproates; Animals; Baclofen; Bicuculline; Electroshock; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Valproic Acid; Vigabatrin | 1982 |
Interrelations between dopaminergic and GABA-ergic transmitter mechanisms in apomorphine stereotypy.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Levodopa; Male; Picrotoxin; Rats; Stereotyped Behavior; Valproic Acid | 1982 |
Strychnine blocks binaural inhibition in lateral superior olivary neurons.
Topics: Acoustic Stimulation; Animals; Bicuculline; Chinchilla; Functional Laterality; gamma-Aminobutyric Acid; Glycine; Neurons; Olivary Nucleus; Picrotoxin; Strychnine | 1983 |
Effects of gamma-aminobutyric acid on neural regulation of the canine sinus node.
Topics: Animals; Blood Pressure; Dogs; Electric Stimulation; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Phentolamine; Picrotoxin; Sinoatrial Node; Vagus Nerve | 1983 |
Role of GABA in the control of thyrotropin secretion in the rat.
Topics: Animals; Circadian Rhythm; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intravenous; Injections, Intraventricular; Male; Picrotoxin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Thyrotropin | 1983 |
Alterations in apomorphine concentration in spinal cord and brain follow the time course of catalepsies induced by different treatments.
Topics: Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; gamma-Aminobutyric Acid; Haloperidol; Humans; Picrotoxin; Rabbits; Spinal Cord; Stereotyped Behavior; Substantia Nigra; Time Factors | 1983 |
GABAergic drugs, morphine and morphine tolerance: a study in relation to nociception and gastrointestinal transit in mice.
Topics: Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Bicuculline; Cyclohexanecarboxylic Acids; Digestion; Digestive System; Digestive System Physiological Phenomena; Drug Tolerance; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Naloxone; Nociceptors; Oxazoles; Picrotoxin | 1983 |
Effects of some amino acids (GABA, glycine, taurine) and of their antagonists (picrotoxin, strychnine) on spatial and temporal features of frog retinal ganglion cell responses.
Topics: Amino Acids; Animals; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Neurons; Picrotoxin; Rana temporaria; Retina; Strychnine; Taurine; Visual Fields | 1980 |
Amino acid and monoamine inhibition of sacral parasympathetic preganglionic neurons.
Topics: 5-Hydroxytryptophan; Animals; Cats; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Neurons; Parasympathetic Nervous System; Picrotoxin; Reflex; Spinal Cord; Strychnine | 1981 |
Involvement of GABA in ganglion cell receptive field organization in the frog retina.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Neurons; Picrotoxin; Rana temporaria; Retina | 1981 |
Effects of picrotoxin on sensitivity and receptive field properties of ganglion cells in the frog retina.
Topics: Animals; Dark Adaptation; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Photoreceptor Cells; Picrotoxin; Rana temporaria; Retina | 1981 |
Perturbation of benzodiazepine receptor binding by pyrazolopyridines involves picrotoxinin/barbiturate receptor sites.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Etazolate; gamma-Aminobutyric Acid; Phenobarbital; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Drug; Sesterterpenes | 1981 |
Depolarizing responses recorded from nodose ganglion cells of the rabbit evoked by 5-hydroxytryptamine and other substances.
Topics: Animals; Dimethylphenylpiperazinium Iodide; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Nodose Ganglion; Picrotoxin; Quipazine; Rabbits; Receptors, Serotonin; Serotonin; Vagus Nerve | 1982 |
Pharmacological investigation of convulsant gamma-aminobutyric acid (GABA) antagonists in amygdala-kindled rats.
Topics: Amygdala; Animals; Convulsants; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1982 |
Pharmacological analysis of directionally sensitive rabbit retinal ganglion cells.
Topics: Acetylcholine; Action Potentials; Animals; gamma-Aminobutyric Acid; Neurons; Photic Stimulation; Physostigmine; Picrotoxin; Rabbits; Retina | 1982 |
A late increase in potassium conductance follows synaptic stimulation of granule neurons of the dentate gyrus.
Topics: Animals; Axons; Electric Conductivity; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium; Rats; Synapses | 1982 |
On the involvement of GABA in the analgesia produced by baclofen, muscimol and morphine.
Topics: 4-Aminobutyrate Transaminase; Analgesia; Analgesics; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Naloxone; Picrotoxin; Transaminases | 1982 |
Gamma-aminobutyric acid can both inhibit and facilitate dopamine release in the caudate nucleus of the rabbit.
Topics: Animals; Bicuculline; Caudate Nucleus; Dopamine; Drug Interactions; Electric Stimulation; Female; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Picrotoxin; Rabbits; Synaptosomes | 1982 |
Multiple actions of picomolar concentrations of flurazepam on the excitability of cultured mouse spinal neurons.
Topics: Animals; Anticonvulsants; Cell Membrane; Cells, Cultured; Electric Conductivity; Flurazepam; gamma-Aminobutyric Acid; Mice; Neurons; Picrotoxin; Spinal Cord | 1982 |
The inhibitory effect of diazepam on conditioned defensive burying is reversed by picrotoxin.
Topics: Animals; Avoidance Learning; Conditioning, Psychological; Diazepam; gamma-Aminobutyric Acid; Male; Motor Activity; Muridae; Picrotoxin | 1982 |
In vivo modulations by GABA-related drugs of met-enkephalin release in basal ganglia of the cat brain.
Topics: Animals; Bicuculline; Cats; Caudate Nucleus; Diazepam; Drug Interactions; Enkephalin, Methionine; Female; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Picrotoxin | 1982 |
A tonic gamma-aminobutyric acid-mediated inhibition of cholinergic amacrine cells in rabbit retina.
Topics: Acetylcholine; Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Photic Stimulation; Picrotoxin; Rabbits; Receptors, Cholinergic; Retina | 1982 |
[Presynaptic component in the mechanism of fenibut action].
Topics: Animals; Baclofen; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Synaptosomes | 1982 |
On the mechanism by which dopamine inhibits prolactin release in the anterior pituitary.
Topics: Animals; Bicuculline; Chlorpromazine; Depression, Chemical; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Male; Mice; Mice, Inbred C57BL; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Sesterterpenes | 1982 |
GABA-mediated negative feedback and color opponency in carp retina.
Topics: Animals; Bicuculline; Carps; Color Perception; Electrophysiology; Feedback; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Perfusion; Photoreceptor Cells; Picrotoxin; Retina; Synapses | 1982 |
The ontogenesis of GABA mediated inhibition of growth hormone release in the sheep.
Topics: Animals; Animals, Newborn; Female; Fetus; gamma-Aminobutyric Acid; Growth Hormone; Muscimol; Picrotoxin; Pregnancy; Sheep | 1982 |
An in vivo method for testing GABAergic compounds.
Topics: Animals; Apomorphine; gamma-Aminobutyric Acid; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Oxazoles; Picrotoxin | 1982 |
The stereotyped behavior syndrome: a new model and proposed therapy.
Topics: Animals; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Haloperidol; Humans; Lithium; Male; Models, Psychological; Penicillins; Picrotoxin; Rats; Stereotyped Behavior; Tetanus Toxin | 1981 |
[GABA-ergic correlates of aggression and intraspecies sociability of mice subjected to isolation].
Topics: Aggression; Alkynes; Aminocaproates; Animals; Bicuculline; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin; Semicarbazides; Social Behavior; Social Isolation | 1981 |
Removal of the telencephalon spares turning induced by injection of GABA agonists and antagonists into the substantia nigra.
Topics: Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Telencephalon; Thalamus | 1980 |
SL 75 102 as a gama-aminobutyric acid agonist: experiments on dorsal root ganglion neurones in vitro.
Topics: Animals; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Guinea Pigs; In Vitro Techniques; Neurons; Picrotoxin | 1981 |
Inhibitory actions of taurocyamine, hypotaurine, homotaurine, taurine and GABA on spike discharges of Purkinje cells, and localization of sensitive sites, in guinea pig cerebellar slices.
Topics: Animals; Cerebellum; Culture Techniques; Evoked Potentials; gamma-Aminobutyric Acid; Guanidines; Guinea Pigs; Interneurons; Neural Inhibition; Picrotoxin; Purkinje Cells; Strychnine; Taurine | 1981 |
Sensitivity of identified medial hypothalamic neurons to GABA, glycine and related amino acids; influence of bicuculline, picrotoxin and strychnine on synaptic inhibition.
Topics: Amino Acids; Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glycine; Hypothalamus; Hypothalamus, Middle; Male; Neural Inhibition; Neurons; Picrotoxin; Rats; Strychnine; Synapses | 1981 |
Effect of GABA agonist and antagonists on cardiovascular and sympathetic responses in SHR and WKY rats.
Topics: Animals; Bicuculline; Cardiovascular Physiological Phenomena; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Rats; Sympathetic Nervous System | 1981 |
Biphasic response of hippocampal pyramidal neurons to GABA.
Topics: Animals; Chlorides; Cobalt; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Iontophoresis; Membrane Potentials; Neurons; Picrotoxin; Rats; Tetrodotoxin | 1981 |
Modification of the macaque's vestibulo-ocular reflex by picrotoxin.
Topics: Animals; Cerebellum; Diazepam; Drug Antagonism; Electrooculography; Eye Movements; gamma-Aminobutyric Acid; Macaca; Picrotoxin | 1981 |
A glutamate-activated chloride conductance on a crustacean muscle.
Topics: Animals; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Ibotenic Acid; Membrane Potentials; Nephropidae; Neural Inhibition; Neuromuscular Junction; Picrotoxin | 1981 |
GABA-mediated synaptic potentials in chick spinal cord and sensory neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Chick Embryo; Chlordiazepoxide; Electrophysiology; gamma-Aminobutyric Acid; Ganglia, Spinal; Neurons; Picrotoxin; Sensory Receptor Cells; Spinal Cord; Strychnine; Synapses; Time Factors | 1981 |
Physiological and pharmacological basis of GABA and glycine action on neurons of mudpuppy retina. II. Amacrine and ganglion cells.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Glycine; Interneurons; Necturus; Neurons; Picrotoxin; Retina; Strychnine | 1981 |
Physiological and pharmacological basis of GABA and glycine action on neurons of mudpuppy retina. III. Amacrine-mediated inhibitory influences on ganglion cell receptive-field organization: a model.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Glycine; Models, Neurological; Necturus; Neural Inhibition; Neurons; Picrotoxin; Retina; Strychnine | 1981 |
Mechanism of participation of medial preoptic area in the hippocampal inhibition of ovulation.
Topics: Animals; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Neural Inhibition; Ovulation; Picrotoxin; Preoptic Area; Rats | 1981 |
Strychnine sensitive inhibition in the dorsal horn of mammalian spinal cord.
Topics: Afferent Pathways; Animals; Cricetinae; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Mice; Neural Inhibition; Picrotoxin; Strychnine | 1981 |
Opposite effects of 5,5-diphenylhydantoin and picrotoxin on GABAergic inhibition in crayfish stretch receptor.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Mechanoreceptors; Membrane Potentials; Phenytoin; Picrotoxin | 1981 |
Opposing actions of convulsants and anticonvulsants on GABA responses of crayfish stretch receptors.
Topics: Animals; Anticonvulsants; Astacoidea; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Phenytoin; Picrotoxin; Synapses | 1981 |
Evaluation of the role of cortical GABA in the induction of abnormal involuntary movements in rats.
Topics: 4-Aminobutyrate Transaminase; Administration, Topical; Animals; Cerebral Cortex; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Picrotoxin; Rats | 1981 |
Effects of GABA on electrical properties of cultured rat pituitary tumor cells: an intracellular recording study.
Topics: Action Potentials; Animals; Bicuculline; Clone Cells; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Picrotoxin; Pituitary Neoplasms; Prolactin; Rats | 1981 |
Direct action of pentobarbitone in potentiating the responses to GABA of rat dorsal root ganglion neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons; Pentobarbital; Picrotoxin; Rats | 1981 |
Effects of anisatin on the GABA action in the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lactones; Membrane Potentials; Neuromuscular Junction; Picrotoxin; Sesquiterpenes; Spiro Compounds | 1981 |
Behavioural effects of GABA-agonists and antagonists infused in the mesencephalic reticular formation - deep layers of superior colliculus.
Topics: Animals; Behavior, Animal; Bicuculline; Dominance, Cerebral; gamma-Aminobutyric Acid; Mesencephalon; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Reticular Formation; Seizures; Superior Colliculi | 1981 |
Possible involvement of gamma-aminobutyric acid in growth hormone release induced by a Met5-enkephalin analog in conscious rats.
Topics: Animals; Bicuculline; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalins; gamma-Aminobutyric Acid; Growth Hormone; Hormones; Kinetics; Male; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains | 1981 |
Effects of 5-hydroxytryptamine on central neurones antagonized by bicuculline and picrotoxin.
Topics: Animals; Bicuculline; Brain; Cerebral Cortex; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Neurons; Picrotoxin; Rats; Serotonin; Serotonin Antagonists | 1981 |
Dihydroergotoxine and the Seizure Threshold.
Topics: Allylglycine; Animals; Brain Chemistry; Catecholamines; Dihydroergotoxine; Drug Interactions; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1981 |
GABA in the entopeduncular nucleus and the subthalamic nucleus participates in mediating dopaminergic striatal output functions.
Topics: Animals; Behavior, Animal; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoxazoles; Male; Mesencephalon; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Thalamic Nuclei | 1981 |
Inhibitory mechanisms of the hyper-irritability caused by picrotoxin in the rat.
Topics: Animals; Brain; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; gamma-Aminobutyric Acid; Hyperesthesia; Male; Norepinephrine; Picrotoxin; Rats; Rats, Inbred Strains; Serotonin; Trigeminal Caudal Nucleus | 1981 |
Pharmacological investigation of gamma aminobutyric acid (GABA) and the development of amygdala-kindled seizures in the rat.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Aminocaproates; Amygdala; Animals; Bicuculline; gamma-Aminobutyric Acid; Imidazoles; Kindling, Neurologic; Male; Pentobarbital; Picrotoxin; Rats; Seizures; Vigabatrin | 1981 |
On the action of the anticonvulsant 5,5-diphenylhydantoin and the convulsant picrotoxin in crayfish stretch receptor.
Topics: Action Potentials; Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Neural Inhibition; Phenytoin; Picrotoxin | 1981 |
Evidence for the involvement of nigrothalamic GABA neurons in circling behaviour in the rat.
Topics: 4-Aminobutyrate Transaminase; Animals; Caudate Nucleus; Corpus Striatum; Electric Stimulation; Ethanolamines; Evoked Potentials; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Motor Activity; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Thalamus | 1981 |
Dopaminergic--GABA-ergic interaction in the nigrostriatal system.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Dopamine; gamma-Aminobutyric Acid; Male; Picrotoxin; Piribedil; Rats; Rats, Inbred Strains; Substantia Nigra | 1981 |
Electrophysiological studies of neurons in the ventral tegmental area of Tsai.
Topics: Animals; Dopamine; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Male; Neural Inhibition; Neural Pathways; Neurons; Nucleus Accumbens; Picrotoxin; Rats; Tegmentum Mesencephali | 1980 |
Anesthetic-dependent excitability changes in the hypothalamic ventromedial nucleus of the rat.
Topics: Amygdala; Animals; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Middle; Neural Inhibition; Neural Pathways; Neurons; Pentobarbital; Picrotoxin; Rats; Urethane | 1980 |
Nucleus accumbens to globus pallidus GABA projection subserving ambulatory activity.
Topics: Animals; Brain Mapping; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Globus Pallidus; Injections, Intraventricular; Locomotion; Male; Nucleus Accumbens; Picrotoxin; Rats; Septal Nuclei | 1980 |
Influence of gamma-aminobutyric acid on lordosis behavior and dopamine activity in estrogen primed spayed female rats.
Topics: Animals; Castration; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Propionates; Rats; Septal Nuclei; Sexual Behavior, Animal; Substantia Nigra | 1980 |
Amygdaloid kindling and the GABA system.
Topics: 4-Aminobutyrate Transaminase; Amygdala; Animals; Electric Stimulation; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Seizures; Transaminases | 1980 |
Antagonism by penicillin of gamma-aminobutyric acid depolarizations at presynaptic sites in rat olfactory cortex and cuneate nucleus in vitro.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Medulla Oblongata; Muscimol; Penicillin G; Penicillins; Picrotoxin; Rats; Synapses | 1980 |
Effects of muscimol and picrotoxin on single unit activity of substantia nigra neurons.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1980 |
Release of endogenous amino acid neurotransmitter candidates from rat olfactory cortex slices: possible regulatory mechanisms and the effects of pentobarbitone.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Male; Muscimol; Olfactory Bulb; Pentobarbital; Picrotoxin; Rats; Taurine | 1980 |
Changes in amino acid concentrations in rat brain after pretreatment with neuroleptic drugs and picrotoxin [proceedings].
Topics: Amino Acids; Animals; Brain; Chlorpromazine; gamma-Aminobutyric Acid; Glutamates; Glutamine; Male; Picrotoxin; Rats; Reserpine | 1980 |
Physiological identification of GABA as the inhibitory transmitter for mammalian cortical neurons in cell culture.
Topics: Animals; Bicuculline; Cerebral Cortex; Culture Techniques; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Neurons; Picrotoxin; Rats; Strychnine; Synapses | 1980 |
Locomotor activity elicited by injections of picrotoxin into the ventral tegmental area is attenuated by injections of GABA into the globus pallidus.
Topics: Afferent Pathways; Animals; gamma-Aminobutyric Acid; Globus Pallidus; Locomotion; Male; Neural Inhibition; Nucleus Accumbens; Picrotoxin; Rats; Synapses; Tegmentum Mesencephali | 1980 |
Antagonism by picrotoxin of 5-hydroxytryptamine-induced excitation of primary afferent neurons.
Topics: Afferent Pathways; Animals; Axons; Carotid Sinus; Cats; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Neurons, Afferent; Nodose Ganglion; Picrotoxin; Serotonin; Serotonin Antagonists; Vagus Nerve | 1980 |
Endogenous inhibitors of picrotoxinin-convulsant binding sites in rat brain.
Topics: Animals; Anticonvulsants; Benzodiazepines; Binding Sites; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Picrotoxin; Purines; Pyrimidines; Rats; Tissue Extracts | 1980 |
Pharmacological blockade of the globus palidus-induced inhibitory response of subthalamic cells in the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glycine; Male; Muscimol; Neurons; Picrotoxin; Rats; Strychnine; Synapses; Thalamus | 1980 |
Locomotor and convulsive responses to picrotoxin in amygdala-kindled rats.
Topics: Amygdala; Animals; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Locomotion; Male; Picrotoxin; Rats; Seizures | 1980 |
GABA mediated circling from substantia nigra.
Topics: Dopamine; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Substantia Nigra | 1980 |
Effect of GABA analogues on blood pressure and central GABA metabolism in the rat.
Topics: 3-Mercaptopropionic Acid; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Blood Pressure; Brain; Dopamine; gamma-Aminobutyric Acid; Heart Rate; Hydroxybutyrates; Male; Muscimol; Picrotoxin; Rats; Sodium Oxybate | 1980 |
L-proline as a glutamate antagonist at a crustacean neuromuscular junction.
Topics: Animals; Astacoidea; Drug Interactions; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Isoleucine; Mathematics; Muscle Contraction; Neuromuscular Junction; Picrotoxin; Proline | 1980 |
Inhibition of depressor cardiovascular reflexes by a derivative of gamma-aminobutyric acid (GABA) and by general anesthetics with suspected GABA-mimetic effects.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Blood Pressure; Cats; Chloralose; Female; gamma-Aminobutyric Acid; Male; Methohexital; Picrotoxin; Reflex; Sympathetic Nervous System; Urethane | 1980 |
Convulsants antagonise inhibition in the olfactory cortex slice.
Topics: Animals; Barbiturates; Bicuculline; Cerebral Cortex; Convulsants; Evoked Potentials; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Membrane Potentials; Neural Conduction; Olfactory Pathways; Picrotoxin | 1980 |
Effects of pentobarbitone on the synaptically evoked release of the amino acid neurotransmitter candidates aspartate and GABA from rat olfactory cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Olfactory Pathways; Pentobarbital; Picrotoxin; Rats; Synapses; Taurine | 1981 |
[Participation of the GABA-ergic system in central regulation of the tonus of resistance and capacitance vessels].
Topics: Animals; Blood Pressure; Brain Mapping; Carotid Sinus; Cats; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Anterior; Hypothalamus, Posterior; Picrotoxin; Preoptic Area; Vascular Resistance | 1981 |
The effect of gamma-aminobutyric acid on the input conductance and membrane potential of Ascaris muscle.
Topics: Animals; Ascaris; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Neural Conduction; Picrotoxin | 1980 |
Evidence for a tonic GABAergic control of serotonin neurons in the median raphe nucleus.
Topics: Animals; Bicuculline; Brain Stem; Diazepam; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Picrotoxin; Probenecid; Raphe Nuclei; Rats; Serotonin | 1981 |
Withdrawal from the endogenous steroid progesterone results in GABAA currents insensitive to benzodiazepine modulation in rat CA1 hippocampus.
Topics: Animals; Benzodiazepines; Brain Chemistry; Chloride Channels; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Ion Channel Gating; Lorazepam; Picrotoxin; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome | 1995 |
GABA-induced chloride current in catfish horizontal cells mediated by non-GABAA receptor channels.
Topics: Animals; Catfishes; Chloride Channels; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Kinetics; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Retina | 1995 |
Subunit composition determines picrotoxin and bicuculline sensitivity of Drosophila gamma-aminobutyric acid receptors.
Topics: Animals; Base Sequence; Bicuculline; Drosophila; Female; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Molecular Sequence Data; Picrotoxin; Receptors, GABA; Spodoptera; Xenopus | 1995 |
Effects of lindane (gamma-BHC) and related convulsants on GABAA receptor-operated chloride channels in frog dorsal root ganglion neurons.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Convulsants; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Ganglia, Spinal; Hexachlorocyclohexane; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Rana catesbeiana; Receptors, GABA-A | 1994 |
[The modulating effect of an optical sensory input on the excitability of the motor center in insects].
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Motor Neurons; Ocular Physiological Phenomena; Periplaneta; Photic Stimulation; Picrotoxin; Sensation; Statistics, Nonparametric | 1994 |
Electrical and synaptic properties of embryonic luteinizing hormone-releasing hormone neurons in explant cultures.
Topics: Action Potentials; Animals; Calcium Channels; Cell Membrane; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Ion Channels; Membrane Potentials; Mice; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Quinine; Synapses; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1995 |
Cone photoreceptors respond to their own glutamate release in the tiger salamander.
Topics: Ambystoma; Animals; Aspartic Acid; Calcium; Chloride Channels; Exocytosis; Fluorescent Dyes; Fura-2; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Retinal Cone Photoreceptor Cells; Synapses; Synaptic Transmission; Time Factors | 1995 |
Enhancement by GABA of the association rate of picrotoxin and tert-butylbicyclophosphorothionate to the rat cloned alpha 1 beta 2 gamma 2 GABAA receptor subtype.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Chlorides; Cloning, Molecular; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Kidney; Kinetics; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, GABA-A | 1995 |
Actions of the insecticide fipronil, on dieldrin-sensitive and- resistant GABA receptors of Drosophila melanogaster.
Topics: Animals; Dieldrin; Dose-Response Relationship, Drug; Drosophila; gamma-Aminobutyric Acid; Insecticides; Membrane Potentials; Oocytes; Picrotoxin; Pyrazoles; Receptors, GABA; Sesterterpenes | 1995 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Astroglial cells express large amounts of GABAA receptor proteins in mature brain.
Topics: Aging; Animals; Astrocytes; Benzodiazepines; Binding Sites; Brain; Cattle; Cells, Cultured; gamma-Aminobutyric Acid; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
A novel gamma-aminobutyric acid response in the embryonic brainstem as revealed by voltage-sensitive dye recording.
Topics: Animals; Baclofen; Brain Stem; Chick Embryo; Coloring Agents; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin | 1995 |
Effect of 2-amino-4-phosphonobutyrate on ERG OFF-response after glycinergic and GABAergic blockade.
Topics: Adaptation, Ocular; Aminobutyrates; Animals; Color; Dark Adaptation; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Picrotoxin; Rana ridibunda; Retina; Strychnine; Synapses; Synaptic Transmission; Time Factors | 1995 |
Interactions of the subthalamic nucleus and the subpallidal area in oro-facial dyskinesia: role of GABA and glutamate.
Topics: Animals; Behavior, Animal; Cats; Facial Muscles; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Male; Mouth; Movement Disorders; Picrotoxin; Thalamic Nuclei; Time Factors | 1995 |
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine | 1993 |
Regulation of GABAA receptor in cerebellar granule cells in culture: differential involvement of kinase activities.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cerebellum; Chloride Channels; Colforsin; Cyclic AMP; Cytoplasmic Granules; Electrophysiology; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Membrane Proteins; Phosphorylation; Phosphotransferases; Picrotoxin; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
GABAB-mediated modulation of ionic conductances in type I hair cells isolated from guinea-pig semicircular canals.
Topics: Animals; Baclofen; Calcium; Cytosol; Electrophysiology; gamma-Aminobutyric Acid; Guinea Pigs; Hair Cells, Auditory; In Vitro Techniques; Ion Channels; Membrane Potentials; Picrotoxin; Semicircular Canals | 1993 |
Strychnine-sensitive glycine receptors in cultured primary neurons from rat neocortex.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebral Cortex; Chloride Channels; Electrophysiology; Female; gamma-Aminobutyric Acid; Glycine; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Picrotoxin; Pregnancy; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Neurotransmitter; Strychnine | 1993 |
Enhancement of gamma-aminobutyric acid-activated chloride channel currents by lanthanides in rat dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Metals, Rare Earth; Neurons; Penicillins; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Terbium; Zinc | 1993 |
Effects of plant diterpenes on the neuronal GABAA receptor-operated chloride current.
Topics: Abietanes; Animals; Chlorides; Diterpenes; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Kinetics; Neurons, Afferent; Osmolar Concentration; Picrotoxin; Plant Extracts; Rana catesbeiana; Receptors, GABA | 1994 |
GABAA receptor-mediated inhibition of N-methyl-D-aspartate-evoked [3H]dopamine release from mesencephalic cell cultures.
Topics: Animals; Baclofen; Cells, Cultured; Dopamine; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mesencephalon; Muscimol; N-Methylaspartate; Picrotoxin; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA; Ventral Tegmental Area | 1994 |
Functional expression of insecticide-resistant GABA receptors from the mosquito Aedes aegypti.
Topics: Aedes; Animals; Baculoviridae; Base Sequence; Chloride Channels; Chromosome Mapping; Cloning, Molecular; Culicidae; DNA Probes; gamma-Aminobutyric Acid; Gene Expression; Genes, Insect; Insecticide Resistance; Membrane Potentials; Molecular Sequence Data; Mutation; Picrotoxin; Receptors, GABA; Transfection | 1994 |
Inhibition in the superior olivary complex: pharmacological evidence from mouse brain slice.
Topics: Animals; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Mice; Neurons; Olivary Nucleus; Picrotoxin; Strychnine | 1995 |
Multiple GABA receptor subtypes mediate inhibition of calcium influx at rat retinal bipolar cell terminals.
Topics: Animals; Axons; Baclofen; Bicuculline; Calcium; Cells, Cultured; gamma-Aminobutyric Acid; Nerve Endings; Organophosphorus Compounds; Picrotoxin; Potassium; Propylamines; Rats; Receptors, GABA; Receptors, GABA-A; Retina | 1995 |
GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Astrocytes; Bicuculline; Brain; Calcium; Calcium Channels; Carbolines; Cell Separation; Chlorides; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Gene Expression; Glial Fibrillary Acidic Protein; Hippocampus; Immunoblotting; In Vitro Techniques; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscimol; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Muscimol; Parasympatholytics; Picrotoxin; Rats; Rats, Sprague-Dawley; Social Behavior | 1995 |
gamma-Aminobutyric acid type A receptor antagonists picrotoxin and bicuculline alter acetylcholine channel kinetics in cultured embryonic rat skeletal muscle.
Topics: Animals; Bicuculline; Cells, Cultured; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Kinetics; Muscle, Skeletal; Picrotoxin; Rats; Receptors, Cholinergic | 1994 |
Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Propofol; Receptors, GABA-A; Strychnine; Xenopus laevis | 1995 |
Dorsal column inhibition of nociceptive thalamic cells mediated by gamma-aminobutyric acid mechanisms in the cat.
Topics: Afferent Pathways; Animals; Baclofen; Cats; Dental Pulp; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Homocysteine; Pain; Picrotoxin; Spinal Cord; Thalamus | 1994 |
Role of glutamatergic synaptic transmission in synchronized discharges of hilar neurons in guinea pig hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Quinoxalines; Receptors, GABA-B; Receptors, Glutamate; Synaptic Transmission; Time Factors | 1993 |
The electrophysiological effects of endogenous GABA in the guinea-pig inferior mesenteric ganglion.
Topics: Acetylcholine; Afferent Pathways; Animals; Bicuculline; Colon; Diazepam; Efferent Pathways; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Mesentery; Physical Stimulation; Picrotoxin; Receptors, GABA | 1993 |
Picrotoxin and pentylene tetrazole induced seizure activity in pyridoxine-deficient rats.
Topics: Animals; Cerebral Cortex; Differential Threshold; Electroencephalography; Electronic Data Processing; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Neurons; Pentylenetetrazole; Picrotoxin; Pyridoxine; Rats; Rats, Sprague-Dawley; Seizures; Thalamus; Vitamin B 6 Deficiency | 1994 |
Spontaneous Ca2+ transients in developing hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aniline Compounds; Animals; Calcium; Calcium Channels; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Lasers; Microscopy, Fluorescence; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Tetrodotoxin; Time Factors; Xanthenes | 1994 |
Age-related changes of GABA-activated chloride channel properties in brain cortex synaptic plasma membrane: evidence for phospholipase involvement.
Topics: Aging; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Diglycerides; gamma-Aminobutyric Acid; Kinetics; Muscimol; Phospholipases; Picrotoxin; Rats; Rats, Wistar; Sulfur Radioisotopes; Synaptic Membranes; Synaptosomes | 1994 |
Effects of inhibition of the GABAergic systems by picrotoxin on retention of a nociceptive experience in the rat, with special reference to the influence of cerebellar cortex output.
Topics: Animals; Brain Mapping; Cerebellar Cortex; Conditioning, Classical; Dose-Response Relationship, Drug; Exploratory Behavior; Female; gamma-Aminobutyric Acid; Mental Recall; Motor Activity; Nociceptors; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Receptors, GABA; Retention, Psychology; Social Environment | 1994 |
GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?
Topics: Acetylcarnitine; Acetylcholine; Action Potentials; Animals; Bicuculline; Chloride Channels; Clonazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Potassium Chloride; Pregnanolone; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Substrate Specificity; Tetrodotoxin; Zinc | 1994 |
Control of impulse conduction in long range branches of afferents by increases and decreases of primary afferent depolarization in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Axons; Bicuculline; Decerebrate State; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neural Conduction; Neurons, Afferent; Picrotoxin; Rats; Rats, Wistar; Spinal Nerve Roots | 1994 |
Excitatory action of gamma-aminobutyric acid (GABA) on crustacean neurosecretory cells.
Topics: Action Potentials; Animals; Astacoidea; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Eye; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Microinjections; Neurites; Neurosecretory Systems; Picrotoxin; Synapses | 1994 |
A novel gamma-aminobutyric acid receptor subunit (rho 2) cloned from human retina forms bicuculline-insensitive homooligomeric receptors in Xenopus oocytes.
Topics: Animals; Bicuculline; Chemical Phenomena; Chemistry; Chloride Channels; Cloning, Molecular; Dose-Response Relationship, Drug; Electrophysiology; Female; gamma-Aminobutyric Acid; Humans; Muscimol; Oocytes; Picrotoxin; Receptors, GABA; Retina; Xenopus | 1994 |
Presynaptic actions of GABA and baclofen in CA1 region of the guinea-pig hippocampus in vitro.
Topics: Animals; Baclofen; Bicuculline; Calcium; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Organophosphorus Compounds; Picrotoxin; Receptors, Presynaptic; Sesterterpenes; Tetrodotoxin | 1994 |
The cell surface progesterone receptor which stimulates calcium influx in human sperm is unlike the A ring reduced steroid site on the GABAA receptor/chloride channel.
Topics: Acrosome; Binding Sites; Calcium; Chloride Channels; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Male; Pentobarbital; Picrotoxin; Progesterone; Receptors, GABA; Receptors, Progesterone; Spermatozoa | 1994 |
Fast presynaptic GABAA receptor-mediated Cl- conductance in cultured rat hippocampal neurones.
Topics: Animals; Bicuculline; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lidocaine; Neurons; Picrotoxin; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Presynaptic; Synapses; Synaptic Transmission; Tetrodotoxin | 1994 |
Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chlorides; Endosulfan; Female; gamma-Aminobutyric Acid; Insecticides; Mice; Pentylenetetrazole; Picrotoxin; Pregnancy; Receptors, GABA-A; Sesterterpenes | 1994 |
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis | 1994 |
[Effect of preliminary administration of phenobarbital on the toxicity of GABA-lytics in mice].
Topics: 3-Mercaptopropionic Acid; Animals; Antidotes; Barbiturates; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Phenobarbital; Picrotoxin; Time Factors | 1993 |
Effects of endothelin-1 (ET-1) and endothelin-3 (ET-3) on convulsive seizures.
Topics: Animals; Anticonvulsants; Bicuculline; Endothelins; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Pentylenetetrazole; Picrotoxin; Seizures; Strychnine | 1994 |
[Myoclonic hyperkinesis induced by repeated administration of picrotoxin into rat neostriatum].
Topics: Animals; Avoidance Learning; gamma-Aminobutyric Acid; Generalization, Stimulus; Hyperkinesis; Male; Microinjections; Myoclonus; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Stereotyped Behavior | 1993 |
A patch-clamp study on a novel gamma-aminobutyric acid activated chloride channel of crayfish deep extensor abdominal muscle.
Topics: Abdominal Muscles; Animals; Astacoidea; Chloride Channels; Electrophysiology; gamma-Aminobutyric Acid; Picrotoxin | 1994 |
Synchronization of inhibitory neurones in the guinea-pig hippocampus in vitro.
Topics: 4-Aminopyridine; Animals; Baclofen; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Membrane Potentials; Microelectrodes; Neurons; Picrotoxin; Pyramidal Cells; Synaptic Transmission | 1994 |
Release of endogenous glutamic and aspartic acids from cerebrocortex synaptosomes and its modulation through activation of a gamma-aminobutyric acidB (GABAB) receptor subtype.
Topics: Animals; Aspartic Acid; Baclofen; Bicuculline; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Male; Organophosphorus Compounds; Picrotoxin; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1993 |
CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium Channels; Quinoxalines; Synapses | 1993 |
[The effect of triorthocresyl phosphate on the toxicity of GABA-lytics for mice].
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Ester Hydrolases; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Male; Mice; Picrotoxin; Synaptic Membranes; Tritolyl Phosphates | 1993 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
Ions required for the electrogenic transport of GABA by horizontal cells of the catfish retina.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Catfishes; Chlorides; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Intracellular Fluid; Ion Transport; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Picrotoxin; Retina; Sodium | 1993 |
Dual action of the cyclodiene insecticide dieldrin on the gamma-aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons.
Topics: Animals; Binding Sites; Chlordiazepoxide; Chloride Channels; Dieldrin; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons, Afferent; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1994 |
GABA transporters and GABAC-like receptors on catfish cone- but not rod-driven horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Chloride Channels; Crotonates; Electrophysiology; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ictaluridae; Kainic Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Muscimol; Organic Anion Transporters; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Stereoisomerism; Time Factors | 1994 |
GABA inhibition of lateral hypothalamic neurons: role of reticular thalamic afferents.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Luteinizing Hormone; Male; Neural Inhibition; Neurons; Neurons, Afferent; Picrotoxin; Rats; Rats, Inbred Strains; Reticular Formation; Thalamus | 1994 |
Further evidence for a functional dorsal-ventral division of the rat striatum: GABAergic involvement in oral movements.
Topics: Animals; Apomorphine; Behavior, Animal; Benzamides; Benzazepines; Carbachol; Corpus Striatum; Dopamine; Flunitrazepam; gamma-Aminobutyric Acid; Jaw; Male; Muscimol; N-Methylscopolamine; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives | 1993 |
Biphasic GABA-A receptor-mediated effect on the spontaneous activity of the circular layer in cat terminal ileum.
Topics: Animals; Atropine; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1993 |
Interacting presynaptic kappa-opioid and GABAA receptors modulate dopamine release from rat striatal synaptosomes.
Topics: Analysis of Variance; Animals; Benzeneacetamides; Bicuculline; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Kinetics; Male; Naltrexone; Narcotics; Oligopeptides; Picrotoxin; Potassium; Pyrrolidines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, kappa; Synaptosomes | 1993 |
Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons.
Topics: 4-Butyrolactone; Animals; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Neurons; Picrotoxin; Rats; Reaction Time | 1993 |
gamma-Aminobutyric acid-induced elevation of intracellular calcium concentration in pituitary cells of neonatal rats.
Topics: Animals; Animals, Newborn; Baclofen; Calcium; Female; Fura-2; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Potassium Chloride; Rats; Rats, Wistar; Receptors, GABA-A; Verapamil | 1993 |
Natural mutation of GABAA receptor alpha 6 subunit alters benzodiazepine affinity but not allosteric GABA effects.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cerebellum; Cloning, Molecular; Convulsants; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Humans; Kidney; Muscimol; Mutation; Picrotoxin; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 1993 |
Structure, pharmacology and function of GABA-A receptors in cochlear outer hair cells.
Topics: Animals; Clorazepate Dipotassium; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Membrane Potentials; Pentobarbital; Picrotoxin; Receptors, GABA-A | 1993 |
GABAergic control of odour-induced activity in the frog olfactory bulb: possible GABAergic modulation of granule cell inhibitory action.
Topics: Action Potentials; Animals; Anisoles; Bicuculline; Camphor; Cyclohexenes; Efferent Pathways; Feedback; gamma-Aminobutyric Acid; Limonene; Odorants; Olfactory Bulb; Pentanols; Picrotoxin; Rana ridibunda; Receptors, GABA; Terpenes | 1993 |
Ipsilateral corticotectal pathway inhibits the formation of long-term potentiation (LTP) in the rat superior colliculus through GABAergic mechanism.
Topics: Animals; Electric Stimulation; Evoked Potentials; Forelimb; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Male; Optic Chiasm; Optic Nerve; Picrotoxin; Pyridoxine; Rats; Rats, Wistar; Somatosensory Cortex; Superior Colliculi; Synaptic Transmission; Visual Cortex; Visual Pathways | 1993 |
[The effect of 3-mercaptopropionic acid on the toxicity of GABA-lytics for mice].
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Ligands; Male; Mice; Picrotoxin; Synaptic Membranes; Time Factors | 1993 |
Effects of serotonin and the 5-HT2/1C receptor agonist DOI on neurons of the cerebellar dentate/interpositus nuclei: possible involvement of a GABAergic interneuron.
Topics: Action Potentials; Amphetamines; Animals; Bicuculline; Cerebellar Nuclei; gamma-Aminobutyric Acid; Interneurons; Iontophoresis; Male; Neurons, Afferent; Picrotoxin; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin; Serotonin Receptor Agonists | 1993 |
GABA-activated chloride channels in secretory nerve endings.
Topics: Animals; Bicuculline; Chlordiazepoxide; Chloride Channels; Chlorides; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Membrane Proteins; Muscimol; Nerve Endings; Picrotoxin; Pituitary Gland, Posterior; Rats; Receptors, GABA-A | 1993 |
Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.
Topics: Action Potentials; Animals; Bicuculline; Culture Techniques; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Pentobarbital; Picrotoxin; Rats; Synapses; Synaptic Transmission; Zinc | 1993 |
Development of spontaneous synaptic activity in culture of the chick spinal cord neurons.
Topics: Animals; Cells, Cultured; Chick Embryo; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Neurons; Picrotoxin; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine; Synapses; Tetrodotoxin | 1993 |
Effects of post-training administration of (-)-baclofen and chlordiazepoxide on memory retention in ICRC Swiss mice: interactions with GABAA and GABAB receptor antagonists.
Topics: Animals; Baclofen; Chlordiazepoxide; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isomerism; Male; Memory; Mice; Mice, Inbred ICR; Motor Activity; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A | 1993 |
Offense produced by chemical stimulation of the anterior hypothalamus of the rat.
Topics: Aggression; Agonistic Behavior; Animals; Brain Mapping; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus, Anterior; Male; Motor Activity; Picrotoxin; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal | 1993 |
Serotonin-containing neurons in lobsters: origins and characterization of inhibitory postsynaptic potentials.
Topics: Aggression; Animals; Behavior, Animal; Clone Cells; gamma-Aminobutyric Acid; Ganglia; Membrane Potentials; Nephropidae; Neural Pathways; Neurons; Octopamine; Parasympatholytics; Picrotoxin; Posture; Serotonin; Serotonin Antagonists; Synapses; Synaptic Transmission | 1993 |
Effects of gabapentin on release of gamma-aminobutyric acid from slices of rat neostriatum.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
Antagonist inhibition of GABAA-mediated chloride uptake is atypical in nigrocollicular areas.
Topics: Animals; Bicuculline; Brain; Chlorides; Chlorine; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inferior Colliculi; Ionophores; Kinetics; Male; Picrotoxin; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stimulation, Chemical; Substantia Nigra; Superior Colliculi | 1993 |
Crayfish tonic inhibition: prolonged modulation of behavioral excitability by classical GABAergic inhibition.
Topics: Abdomen; Animals; Astacoidea; Evoked Potentials; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Models, Neurological; Nervous System; Nervous System Physiological Phenomena; Picrotoxin; Propranolol; Receptors, GABA; Serotonin; Sucrose; Time Factors | 1993 |
Effects of GABA antagonists on inhibitory avoidance.
Topics: Animals; Avoidance Learning; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Picrotoxin; Rats; Rats, Wistar | 1993 |
The substantia innominata complex and the peripeduncular nucleus in orofacial dyskinesia: a pharmacological and anatomical study in cats.
Topics: Animals; Behavior, Animal; Cats; Cholera Toxin; Dyskinesia, Drug-Induced; Face; gamma-Aminobutyric Acid; Histocytochemistry; Male; Mesencephalon; Mouth; Muscimol; Picrotoxin; Substantia Innominata | 1993 |
GABA responses and their partial occlusion by glycine in cultured rat medullary neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Electrophysiology; Evoked Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons; Picrotoxin; Pregnancy; Rats; Strychnine | 1993 |
Pharmacologically induced elements of the hunting and feeding behavior in the pteropod mollusk Clione limacina. I. Effects of GABA.
Topics: Animals; Baclofen; Bicuculline; Brain; Electrophysiology; Extremities; Feeding Behavior; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Ganglia; Immunoenzyme Techniques; Locomotion; Mollusca; Nerve Net; Neurons; Neurons, Efferent; Picrotoxin; Predatory Behavior; Tissue Embedding | 1993 |
GABAergic control of odor-induced activity in the frog olfactory bulb: electrophysiological study with picrotoxin and bicuculline.
Topics: Action Potentials; Animals; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Odorants; Olfactory Bulb; Picrotoxin; Rana ridibunda; Stimulation, Chemical | 1993 |
GABA-induced facilitation of the periodic bursting activity of oxytocin neurones in suckled rats.
Topics: Animals; Animals, Suckling; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Microinjections; Neurons; Osmotic Pressure; Oxytocin; Paraventricular Hypothalamic Nucleus; Periodicity; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Supraoptic Nucleus | 1995 |
Effects of inhibitory amino acids on the frequency components in sympathetic nerve discharge.
Topics: Animals; Cats; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Neurotransmitter Agents; Picrotoxin; Strychnine; Sympathetic Nervous System | 1995 |
GABA transport and calcium dynamics in horizontal cells from the skate retina.
Topics: Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Dantrolene; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscle Relaxants, Central; Nifedipine; Picrotoxin; Retina; Skates, Fish | 1995 |
Electrophysiological characterization of GABAA receptors in anterior pituitary cells of newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Diazepam; Drug Tolerance; Electric Conductivity; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pituitary Gland, Anterior; Rats; Receptors, GABA; Zinc | 1995 |
L-lysine is a barbiturate-like anticonvulsant and modulator of the benzodiazepine receptor.
Topics: Animals; Anions; Anticonvulsants; Barbiturates; Bicuculline; Brain Chemistry; Cattle; Central Nervous System Depressants; Diazepam; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentobarbital; Picrotoxin; Radioligand Assay; Receptors, GABA-A; Stimulation, Chemical | 1995 |
A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Hippocampus; Long-Term Potentiation; Mice; Mice, Mutant Strains; Mutation; Neurons; Phenotype; Picrotoxin; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tissue Plasminogen Activator | 1996 |
GABAergic suppression prevents the appearance and subsequent fatigue of an NMDA receptor-mediated potential in neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Membrane Potentials; Patch-Clamp Techniques; Pentanoic Acids; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
Progesterone induces Ca++-dependent 3',5'-cyclic adenosine monophosphate increase in human sperm.
Topics: Calcimycin; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Genistein; Humans; In Vitro Techniques; Isoflavones; Kinetics; Male; Mifepristone; Picrotoxin; Progesterone; Receptors, GABA-A; Reference Values; Sperm Motility; Spermatozoa; Statistics, Nonparametric | 1996 |
Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms.
Topics: Animals; Carbolines; Cerebellum; Convulsants; Diazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channels; Isomerism; Membrane Potentials; Mice; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Transfection | 1996 |
Cardiovascular neurons in cat caudal ventrolateral medulla: location and characterization of GABAergic input.
Topics: Animals; Antibody Specificity; Blood Pressure; Carbolines; Cardiovascular System; Cats; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Ligands; Male; Medulla Oblongata; Microinjections; Muscimol; Neural Pathways; Neurons; Phenylethanolamine N-Methyltransferase; Picrotoxin; Tyrosine 3-Monooxygenase | 1995 |
Endogenous GABA modulates histamine release from the anterior hypothalamus of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Histamine Release; Hypothalamus, Anterior; Male; Microdialysis; Neurons; Nipecotic Acids; Picrotoxin; Presynaptic Terminals; Proline; Rats; Rats, Wistar | 1996 |
Morphological plasticity in dendritic spines of cultured hippocampal neurons.
Topics: Action Potentials; Animals; Bicuculline; Cells, Cultured; Dendrites; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Microscopy, Confocal; Neuronal Plasticity; Neurons; Picrotoxin; Rats; Rats, Wistar; Tetrodotoxin | 1996 |
Activation of GABAB receptors at individual release boutons of the crayfish opener neuromuscular junction produces presynaptic inhibition.
Topics: Animals; Astacoidea; Baclofen; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neural Conduction; Neural Inhibition; Neuromuscular Junction; Picrotoxin; Presynaptic Terminals | 1996 |
Block of glutamate decarboxylase decreases GABAergic inhibition at the crayfish synapses: possible role of presynaptic metabotropic mechanisms.
Topics: 3-Mercaptopropionic Acid; Aminooxyacetic Acid; Animals; Astacoidea; Baclofen; Chloride Channels; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Models, Neurological; Muscles; Nerve Fibers; Picrotoxin; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1996 |
Role of amino acids in salivation and the localization of their receptors in the rat salivary gland.
Topics: Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, GABA; Salivary Glands; Salivation; Sublingual Gland; Submandibular Gland; Superior Cervical Ganglion | 1995 |
Zinc enhances ionic currents induced in skate Müller (glial) cells by the inhibitory neurotransmitter GABA.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Transport; Neuroglia; Picrotoxin; Receptors, GABA-A; Retina; Signal Transduction; Skates, Fish; Zinc | 1996 |
Pentobarbital modulatory effect on GABA binding sites in developing chick optic lobe.
Topics: Animals; Bicuculline; Brain; Chick Embryo; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Pentobarbital; Picrotoxin; Sesterterpenes; Synaptic Membranes | 1995 |
GABAA receptor binding in the aging rat inferior colliculus.
Topics: Aged; Aging; Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Inferior Colliculi; Ligands; Muscimol; Picrotoxin; Rats; Rats, Inbred F344; Receptors, GABA-A; Tritium | 1996 |
Tests of the motor neuron model of the local pattern-generating circuits in the swimmeret system.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; Glutamic Acid; Models, Neurological; Motor Activity; Motor Neurons; Muscimol; Picrotoxin; Sodium Chloride | 1996 |
Differences in the refractory properties of two distinct inhibitory circuitries in field CA1 of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Long-Term Potentiation; Neural Inhibition; Neuronal Plasticity; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
GABAergic inhibitory inputs to subfornical organ neurons in rat slice preparations.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Subfornical Organ | 1995 |
GABA-induced responses in electrophysiologically characterized neurons within the rat rostro-ventrolateral medulla in vitro.
Topics: Animals; Baclofen; Bicuculline; Brain Stem; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Conduction System; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Synapses | 1996 |
GABAergic modulation of complex spike activity by the cerebellar nucleoolivary pathway in rat.
Topics: Action Potentials; Animals; Biological Clocks; Cerebellar Nuclei; Feedback; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Nerve Fibers; Neural Pathways; Neurons, Afferent; Olivary Nucleus; Picrotoxin; Rats; Rats, Sprague-Dawley; Reflex | 1996 |
Signaling pathway downstream of GABAA receptor in the growth cone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Axons; Binding Sites; Calcium; Chlorides; Diazepam; Fetus; gamma-Aminobutyric Acid; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Neurological; Muscimol; Myristoylated Alanine-Rich C Kinase Substrate; Neurites; Picrotoxin; Prosencephalon; Proteins; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Verapamil | 1996 |
Expression of native GABAA receptors in Xenopus oocytes injected with rat brain synaptosomes.
Topics: Anesthetics; Animals; Brain; Cell Membrane; Chloride Channels; Chlorides; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Rats; Receptors, GABA-A; Synaptosomes; Xenopus laevis; Zinc Compounds | 1996 |
Distinct mechanisms for synchronization and temporal patterning of odor-encoding neural assemblies.
Topics: Animals; Female; GABA Antagonists; gamma-Aminobutyric Acid; Grasshoppers; Male; Membrane Potentials; Neurons, Afferent; Odorants; Olfactory Pathways; Picrotoxin; Receptors, GABA; Sense Organs; Sensory Receptor Cells; Synaptic Transmission | 1996 |
Receptive field of the retinal bipolar cell: a pharmacological study in the tiger salamander.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Animals; Bicuculline; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; In Vitro Techniques; Photoreceptor Cells; Picrotoxin; Receptors, Glycine; Retina; Retinal Cone Photoreceptor Cells; Strychnine; Visual Pathways | 1996 |
Optokinetic and vestibulo-ocular reflex adjustment by GABA antagonists.
Topics: Animals; Cerebellum; Dose-Response Relationship, Drug; Eye Movements; GABA Antagonists; gamma-Aminobutyric Acid; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Reflex, Vestibulo-Ocular; Vestibular Nuclei | 1996 |
Laminar origins of inhibitory synaptic inputs to pyramidal neurons of the rat neocortex.
Topics: Acetylcholine; Animals; Cerebral Cortex; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1996 |
Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons.
Topics: Animals; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Pregnancy; Prohibitins; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Increased probability of GABA release during withdrawal from morphine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Antagonists; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Interneurons; Morphine; Nerve Tissue Proteins; Organophosphorus Compounds; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Picrotoxin; Receptors, GABA-A; Salicylamides; Serotonin; Signal Transduction; Staurosporine; Strychnine; Substance Withdrawal Syndrome; Tegmentum Mesencephali; Thionucleotides | 1997 |
Endogenous activation of mu and delta-1 opioid receptors is required for long-term potentiation induction in the lateral perforant path: dependence on GABAergic inhibition.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1996 |
Functional expression of GABA rho 3 receptors in Xenopus oocytes.
Topics: Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Oocytes; Picrotoxin; Receptors, GABA; Xenopus laevis | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit.
Topics: Animals; Anticonvulsants; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Chloride Channels; Convulsants; Diazepam; DNA, Complementary; Female; gamma-Aminobutyric Acid; Humans; Kinetics; Macromolecular Substances; Male; Membrane Potentials; Oocytes; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Triazoles; Xenopus laevis | 1996 |
Two types of identified ascending interneurons with distinct GABA receptors in the crayfish terminal abdominal ganglion.
Topics: Animals; Astacoidea; Bicuculline; Chlorides; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; In Vitro Techniques; Interneurons; Male; Muscimol; Muscles; Picrotoxin; Receptors, GABA | 1997 |
GABA in locus coeruleus regulates spontaneous rapid eye movement sleep by acting on GABAA receptors in freely moving rats.
Topics: Animals; Electroencephalography; Electromyography; Electrooculography; GABA Antagonists; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Microinjections; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sleep; Sleep, REM; Wakefulness | 1997 |
Picrotoxin-sensitive receptors mediate gamma-aminobutyric acid-induced modulation of synaptic plasticity in rat superior cervical ganglion.
Topics: Animals; Electrophysiology; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Neural Inhibition; Neuronal Plasticity; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Superior Cervical Ganglion | 1997 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Local release of GABAergic inhibition in the motor cortex induces immediate-early gene expression in indirect pathway neurons of the striatum.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Brain Mapping; Corpus Striatum; Cortical Spreading Depression; Deoxyglucose; Dizocilpine Maleate; DNA-Binding Proteins; Early Growth Response Protein 1; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression; Genes, Immediate-Early; Globus Pallidus; Immediate-Early Proteins; Injections, Epidural; Interneurons; Models, Neurological; Motor Activity; Motor Cortex; Neuronal Plasticity; Neurons; Organ Specificity; Picrotoxin; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Receptors, Glutamate; Transcription Factors | 1997 |
Effects of rat galanin and galanin message associated peptide (GMAP) on rat growth hormone secretion and stimulating effect of gamma-aminobutyric acid on galanin release from rat hypothalamus.
Topics: Analysis of Variance; Animals; GABA Antagonists; Galanin; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; Male; Peptide Fragments; Picrotoxin; Pituitary Gland, Anterior; Rats; Rats, Wistar; Stimulation, Chemical | 1997 |
GABA(A) receptor activation triggers a Cl- conductance increase and a K+ channel blockade in cerebellar granule cells.
Topics: Animals; Barium; Bicuculline; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Receptors, GABA-A; Time Factors | 1997 |
Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site.
Topics: 4-Butyrolactone; Animals; Chlordiazepoxide; Female; Flumazenil; gamma-Aminobutyric Acid; Lactones; Phenobarbital; Picrotoxin; Receptors, GABA-A; Xenopus laevis | 1997 |
GABA release in the dorsal raphe nucleus: role in the control of REM sleep.
Topics: Analysis of Variance; Animals; Brain Mapping; Cats; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Homeostasis; Microdialysis; Microinjections; Muscimol; Perfusion; Picrotoxin; Raphe Nuclei; Sleep; Sleep, REM; Time Factors; Wakefulness | 1997 |
Interactions of the neurosteroid dehydroepiandrosterone sulfate with the GABA(A) receptor complex reveals that it may act via the picrotoxin site.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebellum; Cerebral Cortex; Chlorides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Transport; Male; Mice; Mice, Inbred C57BL; Picrotoxin; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1997 |
Inhibitory effects of corymine, an alkaloidal component from the leaves of Hunteria zeylanica, on glycine receptors expressed in Xenopus oocytes.
Topics: Alkaloids; Animals; Bicuculline; Brain; Convulsants; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Midazolam; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Plant Leaves; Rats; Receptors, GABA-A; Receptors, Glycine; Trees; Xenopus | 1997 |
Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Bicuculline; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pain; Picrotoxin; Receptors, GABA; Tail | 1997 |
Retinal direction selectivity after targeted laser ablation of starburst amacrine cells.
Topics: Acetylcholine; Action Potentials; Animals; Cholinergic Antagonists; Dendrites; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Lasers; Motion Perception; Neurons; Picrotoxin; Rabbits; Rats; Receptors, Cholinergic; Retina; Retinal Ganglion Cells; Tubocurarine; Visual Pathways | 1997 |
The interactions of hexachlorocyclohexane isomers with human gamma-aminobutyric acid(A) receptors expressed in Xenopus oocytes.
Topics: Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Humans; Insecticides; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Xenopus | 1997 |
Functional properties of perigeniculate inhibition of dorsal lateral geniculate nucleus thalamocortical neurons in vitro.
Topics: Acetazolamide; Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Convulsants; Electrophysiology; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Male; Membrane Potentials; Neural Inhibition; Neural Pathways; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Thalamic Nuclei | 1997 |
Inhibitory interactions between perigeniculate GABAergic neurons.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Axons; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Excitatory Postsynaptic Potentials; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Male; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Tetrodotoxin; Thalamic Nuclei | 1997 |
Selective antagonism of the GABA(A) receptor by ciprofloxacin and biphenylacetic acid.
Topics: Adenosine Triphosphate; Animals; Bicuculline; Ciprofloxacin; Dimethylphenylpiperazinium Iodide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglionic Stimulants; In Vitro Techniques; Male; Optic Nerve; Phenylacetates; Picrotoxin; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Vagus Nerve | 1997 |
Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzolamide; Bicarbonates; Carbonic Anhydrases; Enzyme Inhibitors; Ethoxzolamide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Models, Neurological; Pentobarbital; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 1997 |
Pharmacology of skeletal muscle GABA-gated chloride channels in the cockroach Periplaneta americana.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Isonicotinic Acids; Male; Motor Neurons; Muscle, Skeletal; Periplaneta; Picrotoxin; Receptors, GABA; Sesterterpenes | 1997 |
Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Arousal; Bicuculline; Blood Pressure; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Picrotoxin; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Currents evoked by GABA and glycine in acutely dissociated neurons from the rat medial preoptic nucleus.
Topics: Animals; Bicuculline; Cells, Cultured; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Ion Channel Gating; Ligands; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Strychnine | 1997 |
Responsiveness to depolarization of hypothalamic neurons secreting somatostatin under stress and estrous cycle conditions: involvement of GABAergic and steroidal interactions.
Topics: Animals; Basal Metabolism; Cells, Cultured; Drug Interactions; Estrus; Female; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Somatostatin; Steroids; Stress, Physiological | 1997 |
Inhibitory cerebello-olivary projections and blocking effect in classical conditioning.
Topics: Action Potentials; Animals; Blinking; Cerebellum; Conditioning, Classical; Evoked Potentials; Feedback; gamma-Aminobutyric Acid; Neural Pathways; Olivary Nucleus; Picrotoxin; Purkinje Cells; Rabbits | 1998 |
Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors.
Topics: Animals; Chlorides; Female; gamma-Aminobutyric Acid; Humans; Leucine; Mutagenesis, Site-Directed; Oocytes; Organophosphorus Compounds; Picrotoxin; Receptors, GABA; Xenopus laevis | 1998 |
Different GABA-receptor types are involved in the 5-HT-induced antinociception at the spinal level: a behavioral study.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Serotonin; Spinal Cord | 1998 |
Age-dependent and cell class-specific modulation of retinal ganglion cell bursting activity by GABA.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Electrophysiology; Female; Ferrets; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Membrane Potentials; Periodicity; Picrotoxin; Pregnancy; Pyridazines; Retinal Ganglion Cells; Strychnine | 1998 |
Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Picrotoxin; Rats; Rats, Sprague-Dawley; Tiagabine; Valproic Acid | 1997 |
GABA modulates color-opponent bipolar cells in carp retina.
Topics: Action Potentials; Animals; Bicuculline; Color Perception; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; Picrotoxin; Receptors, GABA-A; Retina | 1998 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
Carrier-mediated GABA release activates GABA receptors on hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Carrier Proteins; Cells, Cultured; Fetus; GABA Agents; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Neurons; Nipecotic Acids; Organic Anion Transporters; Oximes; Patch-Clamp Techniques; Picrotoxin; Potassium; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium; Tetrodotoxin | 1998 |
GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat.
Topics: Animals; Baclofen; Cocaine; Dopamine; Dopamine Uptake Inhibitors; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Picrotoxin; Piperazines; Rats; Rats, Wistar | 1998 |
Extracellular amino acids in the rat hippocampus during picrotoxin threshold seizures in chronic microdialysis experiments.
Topics: Amino Acids; Animals; Aspartic Acid; Electroencephalography; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Microdialysis; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Taurine | 1998 |
GABA-evoked depolarisations in the rat cortical wedge: involvement of GABAA receptors and HCO3- ions.
Topics: Animals; Bicarbonates; Bicuculline; Cerebral Cortex; Chlordiazepoxide; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Ions; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
Functionally distinct groups of interneurons identified during rhythmic carbachol oscillations in hippocampus in vitro.
Topics: Animals; Carbachol; Cholinergic Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Oscillometry; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses | 1998 |
Ethanol selectively enhances the hyperpolarizing component of neocortical neuronal responses to locally applied GABA.
Topics: Animals; Central Nervous System Depressants; Electrophysiology; Ethanol; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neocortex; Neurons; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1998 |
Embryonic rat hippocampal neurons and GABAA receptor subunit-transfected non-neuronal cells release GABA tonically.
Topics: Animals; Bicuculline; Cell Line; Cells, Cultured; Chloride Channels; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, GABA-A; Sodium Chloride; Transfection | 1998 |
Inhibitory connections between antagonistic motor neurones of the crayfish walking legs.
Topics: 3-Mercaptopropionic Acid; Acetylcholine; Action Potentials; Animals; Astacoidea; Chlorides; Electrophysiology; Female; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Immunoenzyme Techniques; Male; Microscopy, Electron; Motor Neurons; Neural Inhibition; Picrotoxin; Synapses; Tetraethylammonium; Tetrodotoxin; Walking | 1998 |
Functional characterization and visualization of a GABAA receptor-GFP chimera expressed in Xenopus oocytes.
Topics: Anesthetics; Animals; Bicuculline; Cell Membrane; Desoxycorticosterone; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Ion Channel Gating; Luminescent Proteins; Membrane Potentials; Microscopy, Confocal; Midazolam; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Fusion Proteins; Xenopus laevis | 1998 |
Neurotrophins induce formation of functional excitatory and inhibitory synapses between cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Chemistry; Brain-Derived Neurotrophic Factor; Calcium-Binding Proteins; Cell Differentiation; Cell Size; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Membrane Glycoproteins; Membrane Potentials; Microscopy, Electron; Nerve Growth Factors; Nerve Tissue Proteins; Neural Inhibition; Neurons; Neurotrophin 3; Picrotoxin; Rats; Receptors, Glutamate; Synapses; Synapsins; Synaptic Vesicles; Synaptotagmins | 1998 |
Block by picrotoxin of a GABAergic chloride channel expressed on crayfish muscle after axotomy.
Topics: Animals; Astacoidea; Axotomy; Chloride Channels; Dose-Response Relationship, Drug; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Muscles; Picrotoxin; Receptors, GABA | 1998 |
Functional GABA(A) receptors on human glioma cells.
Topics: Anti-Bacterial Agents; Calcium; Calcium Channel Blockers; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Glioblastoma; Gramicidin; Humans; Membrane Potentials; Muscimol; Oligodendroglioma; Patch-Clamp Techniques; Picrotoxin; Potassium; Receptors, GABA-A; Tumor Cells, Cultured; Verapamil | 1998 |
Inhibitory action of CGS 21680 on cerebral cortical neurons is antagonized by bicuculline and picrotoxin-is GABA involved?
Topics: Action Potentials; Adenosine; Animals; Bicuculline; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neurons; Phenethylamines; Picrotoxin; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley | 1998 |
GABA excites immature CA3 pyramidal cells through bicuculline-sensitive and -insensitive chloride-dependent receptors.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Chloride Channels; Culture Techniques; Evoked Potentials; gamma-Aminobutyric Acid; Kynurenic Acid; Nipecotic Acids; Patch-Clamp Techniques; Picrotoxin; Proline; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, GABA-B; Zinc | 1998 |
Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes.
Topics: Aminobutyrates; Anesthesia, General; Anesthetics, Intravenous; Animals; Baclofen; Bicuculline; Calcium; Cerebral Cortex; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Nerve Endings; Nipecotic Acids; Picrotoxin; Potassium Chloride; Proline; Propofol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Synaptic Transmission; Synaptosomes; Tritium | 1998 |
Molecular and pharmacological properties of GABA-rho subunits from white perch retina.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gene Library; Kinetics; Molecular Sequence Data; Oocytes; Perches; Picrotoxin; Receptors, GABA-A; Retina; Sequence Homology, Amino Acid; Xenopus; Zinc | 1998 |
[Effect of microinjection of GABA into the caudate nucleus on electrical discharges of nociceptive neurons in caudate nucleus of rat].
Topics: Animals; Caudate Nucleus; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Nociceptors; Picrotoxin; Rats; Rats, Wistar | 1997 |
Differential effects of GABAA receptor antagonists in the control of respiratory neuronal discharge patterns.
Topics: Animals; Bicuculline; Dogs; Drug Antagonism; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Motor Neurons; Periodicity; Picrotoxin; Receptors, GABA-A; Respiratory Mechanics; Spinal Cord; Stereotaxic Techniques | 1998 |
Dieldrin and picrotoxinin modulation of GABA(A) receptor single channels.
Topics: Animals; Animals, Newborn; Cells, Cultured; Dieldrin; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Insecticides; Ion Channel Gating; Membrane Potentials; Patch-Clamp Techniques; Periodicity; Picrotoxin; Rats; Receptors, GABA-A | 1998 |
[3H]t-butylbicycloorthobenzoate binding to recombinant alpha1beta2gamma2s GABA(A) receptor.
Topics: Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Kidney; Picrotoxin; Radioligand Assay; Receptors, GABA-A; Recombinant Proteins; Thiopental; Tritium | 1998 |
Direct glutamate-mediated presynaptic inhibition of sensory afferents by the postsynaptic motor neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astacoidea; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feedback; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Male; Membrane Potentials; Motor Neurons; Neural Inhibition; Neurons, Afferent; Picrotoxin; Presynaptic Terminals; Quinoxalines; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1998 |
Effects of GABA on acutely isolated neurons from the gustatory zone of the rat nucleus of the solitary tract.
Topics: Animals; Baclofen; Bicuculline; Cell Membrane; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Solitary Nucleus | 1998 |
Expression of functional GABAA receptors in isolated human insulinoma cells.
Topics: Cadmium Chloride; Calcium Channel Blockers; Calcium Channels; Female; gamma-Aminobutyric Acid; Humans; Insulin; Insulin Secretion; Insulinoma; Isradipine; Membrane Potentials; Middle Aged; Muscimol; Pancreatic Neoplasms; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Tumor Cells, Cultured | 1998 |
GABAC receptor rho subunits are heterogeneously expressed in the human CNS and form homo- and heterooligomers with distinct physical properties.
Topics: Animals; Brain Chemistry; Cells, Cultured; Cerebellum; Chlorides; Cloning, Molecular; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Humans; Ion Channel Gating; Kidney; Mammals; Neurons; Picrotoxin; Protein Conformation; Receptors, GABA; Recombinant Fusion Proteins; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection | 1999 |
Rapid desensitization converts prolonged glutamate release into a transient EPSC at ribbon synapses between retinal bipolar and amacrine cells.
Topics: Action Potentials; Ambystoma; Animals; Antihypertensive Agents; Benzothiadiazines; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Ion Channel Gating; Patch-Clamp Techniques; Photic Stimulation; Picrotoxin; Presynaptic Terminals; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Retina; Synaptic Transmission | 1999 |
A reexamination of the role of GABA in the mammalian suprachiasmatic nucleus.
Topics: Action Potentials; Animals; Bicuculline; Cell Membrane Permeability; Chlorides; Circadian Rhythm; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gramicidin; In Vitro Techniques; Male; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Suprachiasmatic Nucleus | 1999 |
Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo.
Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Nerve Degeneration; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Substantia Nigra | 1999 |
Inhibitory control of LTP and LTD: stability of synapse strength.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Long-Term Potentiation; Neural Inhibition; Neuronal Plasticity; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 1999 |
Inhibition of GABA-gated chloride channels by 12,14-dichlorodehydroabietic acid in mammalian brain.
Topics: Abietanes; Amphotericin B; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Diterpenes; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; Phenanthrenes; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kinetics; Lead; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channels; Sodium Channels; Synaptic Transmission; Tetrodotoxin | 1999 |
Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors.
Topics: Animals; Chloride Channels; Dehydroepiandrosterone Sulfate; Female; gamma-Aminobutyric Acid; Macromolecular Substances; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Picrotoxin; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1999 |
GABA(A) receptors mediate inhibition of T cell responses.
Topics: Amidines; Animals; Autocrine Communication; Bicuculline; CD3 Complex; Cell Division; Enzyme Inhibitors; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hypersensitivity, Delayed; Immunosuppression Therapy; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred NOD; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; T-Lymphocytes; Vigabatrin | 1999 |
Gamma-aminobutyric acid (GABA) A and B receptors mediate the stimulatory effects of GABA on the human sperm acrosome reaction: interaction with progesterone.
Topics: Acrosome; Analysis of Variance; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Picrotoxin; Progesterone; Prospective Studies; Receptors, GABA-A; Receptors, GABA-B | 1999 |
Excitatory effects of adenosine are not mediated by inhibition of GABAergic system in slices of superior colliculus and hippocampus from guinea pig.
Topics: Action Potentials; Adenosine; Animals; Enzyme Inhibitors; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Indoles; Maleimides; Neural Inhibition; Picrotoxin; Protein Kinase C; Superior Colliculi | 1999 |
Sodium action potentials are not required for light-evoked release of GABA or glycine from retinal amacrine cells.
Topics: Action Potentials; Ambystoma; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; In Vitro Techniques; Photic Stimulation; Picrotoxin; Retina; Sodium Channel Blockers; Sodium Channels; Strychnine; Tetrodotoxin | 1999 |
Bicuculline-resistant, Cl- dependent GABA response in the rat spinal dorsal horn.
Topics: Animals; Bicuculline; Chloride Channels; Evoked Potentials; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Gelatinosa; Thiopental | 1999 |
Cerebrovascular evidence for a GABAergic modulation of the cholinergic vasodilatatory basalocortical system in the rat.
Topics: Animals; Carbachol; Carbolines; Cerebrovascular Circulation; Cholinergic Agents; Cholinergic Fibers; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Injections; Male; Picrotoxin; Rats; Rats, Sprague-Dawley; Substantia Innominata; Vasodilation | 1999 |
Role of nitric oxide on GABA, glutamic acid, activities of GABA-T and GAD in rat brain cerebral cortex.
Topics: 4-Aminobutyrate Transaminase; Animals; Arginine; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Picrotoxin; Rats; Rats, Wistar | 1999 |
Cl- accumulation does not account for the depolarizing phase of the synaptic GABA response in hippocampal pyramidal cells.
Topics: Animals; Chlorides; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Synapses | 1999 |
Anisatin modulation of the gamma-aminobutyric acid receptor-channel in rat dorsal root ganglion neurons.
Topics: Affinity Labels; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Electric Stimulation; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Insecticides; Kinetics; Lactones; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Plants; Rats; Receptors, GABA; Sesquiterpenes; Sesterterpenes; Spiro Compounds | 1999 |
Role of GABAA and GABAC receptors in the biphasic GABA responses in neurons of the rat major pelvic ganglia.
Topics: Animals; Bicuculline; Drug Resistance; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Parasympathetic; Male; Membrane Potentials; Neurons; Pelvis; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A | 1999 |
Clonidine action in spontaneously hypertensive rats (SHR) depends on the GABAergic system function.
Topics: Animals; Antihypertensive Agents; Bicuculline; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Down-Regulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Medulla Oblongata; Picrotoxin; Pons; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine.
Topics: Allosteric Regulation; Animals; Bicuculline; Conserved Sequence; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Leucine; Mutagenesis, Site-Directed; Mutation; Picrotoxin; Protein Structure, Tertiary; Rats; Receptors, GABA-A | 1999 |
Effects of GABAergic system on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Morphine Dependence; Muscimol; Naloxone; Narcotic Antagonists; Organophosphorus Compounds; Picrotoxin; Substance Withdrawal Syndrome | 1999 |
Synaptic membrane freezing affects modulatory sites in avian central nervous system GABA(A) receptor.
Topics: Animals; Binding Sites; Chickens; Drug Synergism; Freezing; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Pentobarbital; Picrotoxin; Pregnanolone; Receptors, GABA-A; Sesterterpenes; Synaptic Membranes; Tectum Mesencephali; Tritium | 1999 |
Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.
Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Binding Sites; Biphenyl Compounds; Cell Membrane; Central Nervous System Depressants; Cerebellum; Diflunisal; Drugs, Chinese Herbal; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Lignans; Muscimol; Picrotoxin; Propofol; Prosencephalon; Rats; Receptors, GABA-A; Tritium | 1999 |
GABAergic modulation of neocortical long-term potentiation in the freely moving rat.
Topics: Animals; Diazepam; Electric Stimulation; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Neocortex; Picrotoxin; Rats; Rats, Long-Evans; Receptors, GABA-A | 2000 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
Spontaneous and locomotor-related GABAergic input onto primary afferents in the neonatal rat.
Topics: Action Potentials; Afferent Pathways; Animals; Animals, Newborn; Bicuculline; Brain Stem; Chlorides; Decerebrate State; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Motor Activity; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Spinal Nerve Roots | 2000 |
gamma-Aminobutyric acid infusion in substantia nigra pars reticulata in rats inhibits ascorbate release in ipsilateral striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Corpus Striatum; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Infusions, Parenteral; Male; Picrotoxin; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2000 |
Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbolines; Convulsants; Electroencephalography; Epilepsy, Absence; Frontal Lobe; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoniazid; Kainic Acid; Limbic System; Male; Parietal Lobe; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Strychnine | 2000 |
GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Pregnanediones; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Changing subcellular distribution and activity-dependent utilization of a dendritically localized mRNA in developing Purkinje cells.
Topics: Animals; Cells, Cultured; Cerebellum; Dactinomycin; Dendrites; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Guanine Nucleotide Exchange Factors; Mice; Neuronal Plasticity; Neuropeptides; Nucleic Acid Synthesis Inhibitors; Picrotoxin; Potassium; Purkinje Cells; RNA, Messenger; Subcellular Fractions | 2000 |
Effects of L-arginine on picrotoxin-induced increase in brain ammonia concentrations and convulsions in rats.
Topics: Ammonia; Animals; Anticonvulsants; Arginine; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Wistar; Seizures; Tissue Distribution | 1999 |
Copper sensitivity in dorsal hippocampus slices.
Topics: Action Potentials; Animals; Bicuculline; Copper Sulfate; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Synapses | 2000 |
Guanosine and GMP prevent seizures induced by quinolinic acid in mice.
Topics: Animals; Anticonvulsants; Central Nervous System; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Guanosine; Guanosine Monophosphate; Male; Mice; Neurons; Picrotoxin; Quinolinic Acid; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Seizures; Time Factors | 2000 |
Taurine activates GABA(A) but not GABA(B) receptors in rat hippocampal CA1 area.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Organ Culture Techniques; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synapses; Taurine; Tetrodotoxin | 2000 |
Characterisation of GABA(A) receptors in fetal, neonatal and adult ovine brain: region and age related changes and the effects of allopregnanolone.
Topics: Aging; Animals; Animals, Newborn; Binding, Competitive; Brain; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Female; Fetus; Frontal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Picrotoxin; Pregnancy; Pregnanolone; Receptors, GABA-A; Sheep; Sulfur Radioisotopes | 2000 |
Corticothalamic inputs control the pattern of activity generated in thalamocortical networks.
Topics: Animals; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Female; Ferrets; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; In Vitro Techniques; Male; Microelectrodes; Nerve Net; Neural Conduction; Neurons; Organophosphorus Compounds; Picrotoxin; Reaction Time; Thalamus | 2000 |
Similar levels of long-term potentiation in amyloid precursor protein -null and wild-type mice in the CA1 region of picrotoxin treated slices.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Central Nervous System Stimulants; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Long-Term Potentiation; Mice; Mice, Knockout; Neural Inhibition; Organ Culture Techniques; Picrotoxin | 2000 |
Distribution of functional glutamate and GABA receptors on hippocampal pyramidal cells and interneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Polarity; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Lysine; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Rats; Receptors, GABA; Receptors, Glutamate; Synapses | 2000 |
The alpha and gamma subunit-dependent effects of local anesthetics on recombinant GABA(A) receptors.
Topics: Anesthetics, Local; Animals; Bupivacaine; DNA, Recombinant; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Lidocaine; Membrane Potentials; Mice; Oocytes; Picrotoxin; Procaine; Receptors, GABA-A; RNA, Complementary; Tetracaine; Xenopus laevis | 2000 |
Subcellular localization and complements of GABA(A) and GABA(C) receptors on bullfrog retinal bipolar cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cell Compartmentation; Cell Size; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Histamine; Imidazoles; Isoquinolines; Membrane Potentials; Picrotoxin; Presynaptic Terminals; Rana catesbeiana; Receptors, GABA; Receptors, GABA-A; Retina | 2000 |
Single channel analysis of the blocking actions of BIDN and fipronil on a Drosophila melanogaster GABA receptor (RDL) stably expressed in a Drosophila cell line.
Topics: Animals; Bridged Bicyclo Compounds; Cell Line; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Nitriles; Patch-Clamp Techniques; Picrotoxin; Pyrazoles; Receptors, GABA-A; Time Factors | 2000 |
Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anticonvulsants; Arachidonic Acid; Binding, Competitive; Cells, Cultured; Cyclooxygenase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Fatty Acids; Fatty Acids, Monounsaturated; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Indomethacin; Kidney; Linoleic Acid; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection; Triazoles | 2000 |
Novel mechanism for presynaptic inhibition: GABA(A) receptors affect the release machinery.
Topics: Action Potentials; Animals; Astacoidea; Baclofen; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Fura-2; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Intracellular Fluid; Magnesium; Neural Inhibition; Neuromuscular Junction; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Reaction Time; Receptors, GABA-A; Synaptic Transmission; Temperature | 2000 |
GABA receptor antagonists modulate postmitotic cell migration in slice cultures of embryonic rat cortex.
Topics: Animals; Baclofen; Bicuculline; Bromodeoxyuridine; Cell Movement; Cellular Senescence; Cerebral Cortex; Chemotaxis; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Intermediate Filament Proteins; Mitosis; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Organ Culture Techniques; Picrotoxin; Pregnancy; Rats; Receptors, GABA-A | 2000 |
Evidence for coassembly of mutant GABAC rho1 with GABAA gamma2S, glycine alpha1 and glycine alpha2 receptor subunits in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; In Vitro Techniques; Mutagenesis; Neural Inhibition; Oocytes; Picrotoxin; Protein Structure, Tertiary; Rats; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Glycine; Retina; Xenopus laevis | 2000 |
Pharmacology of GABA(A) receptors of retinal dopaminergic neurons.
Topics: Alkaline Phosphatase; Animals; Benzodiazepines; Bicuculline; Binding Sites; Dopamine; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Neurons; Osmolar Concentration; Patch-Clamp Techniques; Picrotoxin; Pregnanediones; Protein Isoforms; Receptors, GABA-A; Retina; Sesterterpenes; Triazoles; Zinc | 2000 |
Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.
Topics: Animals; Behavior, Animal; Bumetanide; Carrier Proteins; Cells, Cultured; Chlorides; Contraindications; Female; GABA Antagonists; GABA-A Receptor Antagonists; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Ganglia, Spinal; Gramicidin; Male; Membrane Potentials; Mice; Mice, Knockout; Neurons; Pain Measurement; Patch-Clamp Techniques; Picrotoxin; Potassium; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters | 2000 |
Expression of GABA(C) receptor rho1 and rho2 subunits during development of the mouse retina.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Neurons, Afferent; Organophosphorus Compounds; Picrotoxin; Receptors, GABA; Retina; RNA, Messenger | 2000 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected].
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Bicuculline; Cells, Cultured; Female; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA-A; Steroids; Xenopus laevis | 2000 |
Reduced long-term potentiation in hippocampal slices prepared using sucrose-based artificial cerebrospinal fluid.
Topics: Action Potentials; Animals; Cerebrospinal Fluid; Culture Techniques; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Picrotoxin; Pyramidal Cells; Sodium Chloride; Sucrose; Synaptic Transmission | 2000 |
Two novel residues in M2 of the gamma-aminobutyric acid type A receptor affecting gating by GABA and picrotoxin affinity.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; gamma-Aminobutyric Acid; Models, Biological; Molecular Sequence Data; Picrotoxin; Point Mutation; Receptors, GABA-A; Structure-Activity Relationship | 2001 |
Multireceptor GABAergic regulation of synaptic communication in amphibian retina.
Topics: Ambystoma; Animals; Cell Communication; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Light; Organophosphorus Compounds; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Pyridazines; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synapses | 2001 |
Effects of gamma-HCH and delta-HCH on human recombinant GABA(A) receptors: dependence on GABA(A) receptor subunit combination.
Topics: Allosteric Regulation; Animals; Barbiturates; Binding Sites; Drug Synergism; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Humans; Oocytes; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 2001 |
Swim stress alters the behavioural response of mice to GABA-related and some GABA-unrelated convulsants.
Topics: Animals; Behavior, Animal; Convulsants; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Mice, Inbred CBA; Picrotoxin; Seizures; Stress, Physiological; Swimming; Temperature; Water | 2001 |
Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Chickens; Convulsants; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Picrotoxin; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Sulfur Radioisotopes; Thalamus; Tritium | 2001 |
Glycinergic and GABAergic control of intensity-response function of frog ERG waves under different conditions of light stimulation.
Topics: Animals; Color Perception; Dark Adaptation; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; In Vitro Techniques; Photic Stimulation; Picrotoxin; Rana ridibunda; Retina; Strychnine; Time Factors | 2000 |
Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia.
Topics: Amygdala; Animals; Dentate Gyrus; Disease Models, Animal; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Isoenzymes; Male; Neural Pathways; Neurons; Picrotoxin; Postmortem Changes; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia | 2001 |
Activation of neostriatal dopaminergic system in rats prevents toxic effects of picrotoxin administered into globus pallidus.
Topics: Amphetamine; Animals; Dopamine; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Motor Activity; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Seizures | 2000 |
The supramammillary nucleus contributes to associative EPSP-spike potentiation in the rat dentate gyrus in vivo.
Topics: Animals; Dentate Gyrus; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus, Posterior; Long-Term Potentiation; Male; Perforant Pathway; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Anxiolytic and anticonvulsant properties of doramectin in rats: behavioral and neurochemistric evaluations.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Brain Chemistry; Convulsants; Female; gamma-Aminobutyric Acid; Grooming; Ivermectin; Motor Activity; Neurotransmitter Agents; Picrotoxin; Rats; Rats, Wistar; Synaptic Transmission | 2000 |
GABA(A) and GABA(B) receptors on neocortical neurons are differentially distributed.
Topics: Animals; Cell Compartmentation; Dendrites; GABA Antagonists; gamma-Aminobutyric Acid; Lasers; Male; Membrane Potentials; Neocortex; Organ Culture Techniques; Patch-Clamp Techniques; Photic Stimulation; Photochemistry; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Tetrodotoxin | 2001 |
The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats.
Topics: Adrenergic Agents; Animals; Anxiety; Apomorphine; Avoidance Learning; Disease Models, Animal; Dopamine; Dopamine Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus, Middle; Male; Memantine; Microinjections; Neurotransmitter Agents; Phenylephrine; Picrotoxin; Rats; Serotonin; Sulpiride; Yohimbine | 2001 |
Functional pharmacology of GABA(A) receptors containing the chicken brain gamma 4 subunit.
Topics: Animals; Bicuculline; Brain Chemistry; Chickens; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis; Zinc | 2001 |
Interactions between cholinergic and GABAergic neurotransmitters in and around the locus coeruleus for the induction and maintenance of rapid eye movement sleep in rats.
Topics: Acetylcholine; Animals; Carbachol; Cerebral Cortex; Cholinergic Agonists; Drug Interactions; Electroencephalography; Eye Movements; GABA Antagonists; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Muscarinic Antagonists; Muscle Tonus; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Scopolamine; Sleep, REM | 2001 |
Sevoflurane potentiates and blocks GABA-induced currents through recombinant alpha1beta2gamma2 GABAA receptors: implications for an enhanced GABAergic transmission.
Topics: Anesthetics, Inhalation; Bicuculline; Cell Line; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Kidney; Methyl Ethers; Picrotoxin; Receptors, GABA-A; Sevoflurane; Synaptic Transmission | 2001 |
DL-Tetrahydropalmatine may act through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats.
Topics: Amygdala; Animals; Berberine Alkaloids; Dopamine; Dopamine Antagonists; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Hyperkinesis; Male; Motor Activity; Neural Inhibition; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley | 2001 |
GABA enhances transmission at an excitatory glutamatergic synapse.
Topics: Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; Motor Neurons; Muscimol; Muscles; Nephropidae; Neuromuscular Junction; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-B; Synapses; Synaptic Transmission | 2001 |
Involvement of GABAergic systems in manifestation of pharmacological activity of desipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Baclofen; Desipramine; Freund's Adjuvant; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Reaction Time | 2001 |
GABA exerts opposite influence on warm and cold sensitive neurons in medial preoptic area in rats.
Topics: Animals; Cold Temperature; GABA Antagonists; gamma-Aminobutyric Acid; Hot Temperature; Iontophoresis; Male; Microinjections; Neural Inhibition; Neurons, Afferent; Picrotoxin; Preoptic Area; Rats; Rats, Wistar; Thermosensing | 2001 |
Evidence for an involvement of the ammonia-decreasing action of L-arginine in suppressing picrotoxin-induced convulsions in rats and its additive action with diazepam.
Topics: Ammonia; Animals; Arginine; Brain; Diazepam; Drug Interactions; Epilepsy; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hyperammonemia; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Seizures; Synaptic Transmission | 2001 |
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Injections, Intraventricular; Male; Mice; Pentobarbital; Picrotoxin; Pyrazines; Seizures; Sleep; Time Factors; Valproic Acid | 2001 |
GABA(C) rho(1) subunits form functional receptors but not functional synapses in hippocampal neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Drug Resistance; Forecasting; gamma-Aminobutyric Acid; Hippocampus; Humans; Indicators and Reagents; Neural Inhibition; Neurons; Picrotoxin; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Ruthenium Red; Synapses; Synaptic Transmission | 2001 |
GABAergic neurons in prepositus hypoglossi regulate REM sleep by its action on locus coeruleus in freely moving rats.
Topics: Animals; Central Nervous System Stimulants; Electric Stimulation; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Medulla Oblongata; Microinjections; Motor Activity; Neural Pathways; Neurons; Picrotoxin; Rats; Rats, Wistar; Sleep, REM; Wakefulness | 2001 |
Cholinergic transmission via central synapses in the locust nervous system.
Topics: Acetylcholine; Animals; Atropine; Bicuculline; Bungarotoxins; Carbachol; Crotonates; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Grasshoppers; Interneurons; Muscimol; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Picrotoxin; Receptors, Nicotinic; Synapses; Synaptic Transmission; Tubocurarine | 2001 |
Two new actions of topiramate: inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Carbonic Anhydrases; Electric Stimulation; Electrophysiology; Fructose; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Picrotoxin; Potassium Channels; Rats; Rats, Sprague-Dawley; Synapses; Topiramate | 2002 |
Cerebellar cortical inhibition and classical eyeblink conditioning.
Topics: Action Potentials; Animals; Blinking; Cerebellum; Cerebral Cortex; Conditioning, Classical; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Purkinje Cells; Rabbits; Receptors, GABA-A; Receptors, Glutamate | 2002 |
Role of inhibition for temporal and spatial odor representation in olfactory output neurons: a calcium imaging study.
Topics: Animals; Bees; Calcium; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Neural Inhibition; Neural Pathways; Odorants; Olfactory Receptor Neurons; Picrotoxin; Smell | 2002 |
Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy.
Topics: Acetylcholine; Action Potentials; Aggression; Animals; Behavior, Animal; Brain; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscarinic Agonists; Nerve Degeneration; Neural Pathways; Neurons; Picrotoxin; Pilocarpine; Rats; Rats, Wistar; Reaction Time; Statistics as Topic | 2002 |
GABAergic and glutamatergic modulation of spontaneous and motor-cortex-evoked complex spike activity.
Topics: Action Potentials; Animals; Central Nervous System Stimulants; Cerebellum; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Motor Cortex; Nerve Fibers; Neural Inhibition; Neurons, Afferent; Olivary Nucleus; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Synapses | 2002 |
Subunit composition and function of GABAA receptors of rat spermatozoa.
Topics: Animals; Base Sequence; Bicuculline; DNA Primers; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Protein Subunits; Rats; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermatozoa; Transcription, Genetic | 2002 |
Picrotoxin and bicuculline have different effects on lumbar spinal networks and motoneurons in the neonatal rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Interneurons; Motor Neurons; Nerve Net; Neural Inhibition; Neural Pathways; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Synaptic Transmission | 2002 |
Reorganization of the GABAergic system following brain extirpation in the earthworm (Eisenia fetida, Annelida, Oligochaeta).
Topics: Animals; Brain; Cell Movement; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Oligochaeta; Picrotoxin; Regeneration; Time Factors | 2002 |
gamma-aminobutyric acid transporter-mediated current from bipolar cells in tiger salamander retinal slices.
Topics: Animals; Carrier Proteins; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ion Channels; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Oximes; Patch-Clamp Techniques; Picrotoxin; Retina; Sodium; Urodela | 1998 |
Apnoeic response to stimulation of peripheral GABA receptors in rats.
Topics: Animals; Apnea; Bicuculline; Carotid Sinus; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Respiration; Respiratory Mechanics; Vagotomy | 2002 |
Oscillations and sparsening of odor representations in the mushroom body.
Topics: Action Potentials; Animals; Electric Stimulation; Electrodes; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Grasshoppers; Interneurons; Male; Mushroom Bodies; Nerve Net; Neural Inhibition; Neurons; Odorants; Patch-Clamp Techniques; Picrotoxin; Smell; Synaptic Transmission; Time Factors | 2002 |
Cloning and functional characterization of two glycine receptor alpha-subunits from the perch retina.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Cloning, Molecular; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Molecular Sequence Data; Perches; Picrotoxin; Receptors, Glycine; Retina; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Strychnine; Taurine | 2002 |
Peripheral GABAergic inhibition of spider mechanosensory afferents.
Topics: Afferent Pathways; Animals; Bicuculline; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Neurons, Afferent; Patch-Clamp Techniques; Picrotoxin; Sodium Channels; Spiders | 2002 |
Detection of molecules related to the GABAergic system in a single-cell eukaryote, Paramecium primaurelia.
Topics: 4-Aminobutyrate Transaminase; Acetylcholine; Aldehyde Oxidoreductases; Animals; Antibodies; Bicuculline; Boron Compounds; Choline O-Acetyltransferase; Fluorescent Dyes; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Paramecium; Picrotoxin; Receptors, GABA-A | 2002 |
Electrophysiological analysis of synaptic transmission in central neurons of Drosophila larvae.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Action Potentials; Animals; Calcium; Central Nervous System; Drosophila; Drosophila Proteins; Dynamins; Electric Stimulation; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; GTP Phosphohydrolases; Mutation; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Picrotoxin; Receptors, Nicotinic; Synaptic Transmission; Tubocurarine | 2002 |
Evidence for an involvement of nitric oxide and gamma aminobutyric acid in the anticonvulsant action of L-arginine on picrotoxin-induced convulsions in rats.
Topics: Animals; Anticonvulsants; Arginine; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Nitric Oxide; Picrotoxin; Rats; Rats, Wistar; Seizures | 2002 |
Gaba-benzodiazepine receptor complex in brain oxidative metabolism regulation.
Topics: Animals; Diazepam; Flumazenil; Frontal Lobe; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Oxygen Consumption; Picrotoxin; Rats; Rats, Wistar | 2002 |
A neurosteroid anesthetic, alphaxalone, inhibits nicotinic acetylcholine receptors in cultured bovine adrenal chromaffin cells.
Topics: Anesthetics; Animals; Calcium Channel Blockers; Cattle; Cells, Cultured; Chromaffin Cells; gamma-Aminobutyric Acid; Nicotine; Patch-Clamp Techniques; Perfusion; Picrotoxin; Pregnanediones; Receptors, GABA-A; Receptors, Nicotinic | 2002 |
Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors.
Topics: Cell Line; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Kinetics; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA-A; Structure-Activity Relationship; Transfection | 2002 |
Functional characterization of GABA(A) receptors in neonatal hypothalamic brain slice.
Topics: Anesthetics; Animals; Animals, Newborn; Anticonvulsants; Carbolines; Convulsants; Dehydroepiandrosterone Sulfate; Diazepam; Diuretics; Female; Furosemide; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hypothalamus; Male; Membrane Potentials; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Pregnanolone; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles; Zinc; Zolpidem | 2002 |
Overexpression of the GABA(A) receptor epsilon subunit results in insensitivity to anaesthetics.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Blotting, Western; Cell Line; Cloning, Molecular; DNA, Complementary; Etomidate; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Pentobarbital; Picrotoxin; Protein Engineering; Receptors, GABA-A; Steroids; Transfection; Xenopus laevis | 2002 |
Relative picrotoxin insensitivity distinguishes ionotropic GABA receptor-mediated IPSCs in hippocampal interneurons.
Topics: Animals; Bicuculline; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Iontophoresis; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyramidal Cells; Pyridines; Receptors, GABA; Receptors, GABA-A; Zolpidem | 2002 |
Modulation of GABA(A) receptor-mediated currents by benzophenone derivatives in isolated rat Purkinje neurones.
Topics: Animals; Benzophenones; Cell Separation; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; Patch-Clamp Techniques; Penicillin G; Picrotoxin; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-A; Structure-Activity Relationship | 2002 |
Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Female; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Oocytes; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis | 2002 |
The lemniscal-cuneate recurrent excitation is suppressed by strychnine and enhanced by GABAA antagonists in the anaesthetized cat.
Topics: Action Potentials; Animals; Bicuculline; Cats; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Male; Neural Inhibition; Neural Pathways; Neurons; Occipital Lobe; Picrotoxin; Skin; Strychnine | 2002 |
Fast synaptic transmission between striatal spiny projection neurons.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Memory, Short-Term; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Substantia Nigra; Synapses; Synaptic Transmission | 2002 |
Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.).
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sea Bream | 2002 |
GABA-glutamate interaction in the control of BDNF expression in hypothalamic neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Enzyme-Linked Immunosorbent Assay; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Male; Neurons; Nuclease Protection Assays; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptor, trkB; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 2003 |
[Locomotor behavior in rats after separate and simultaneous intrastriatal microinjections of GABA-ergic drugs].
Topics: Animals; Avoidance Learning; Behavior, Animal; Bicuculline; Conditioning, Classical; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Motor Activity; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 2002 |
From synchrony to sparseness.
Topics: Action Potentials; Animals; Electric Stimulation; Electrodes; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Grasshoppers; Interneurons; Male; Mushroom Bodies; Nerve Net; Neural Inhibition; Neurons; Odorants; Patch-Clamp Techniques; Picrotoxin; Smell; Synaptic Transmission; Time Factors | 2003 |
The ATP-mediated fast current of rat dorsal root ganglion neurons is a novel effector for GABA(B) receptor activation.
Topics: Adenosine Triphosphate; Animals; Baclofen; Benzylamines; Cells, Cultured; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Rats; Receptors, GABA-A; Receptors, GABA-B; Receptors, Purinergic P2; Receptors, Purinergic P2X3 | 2003 |
Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, is an antagonist at recombinant alpha1beta2gamma2L GABA(A) receptors.
Topics: Animals; Bicuculline; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Furans; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ginkgo biloba; Ginkgolides; Humans; Membrane Potentials; Oocytes; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Sesterterpenes; Xenopus laevis | 2003 |
GABAB receptor-mediated presynaptic potentiation of ATP ionotropic receptors in rat midbrain synaptosomes.
Topics: Adenosine Triphosphate; Animals; Baclofen; Calcium; Colforsin; Competitive Bidding; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Vitro Techniques; Mesencephalon; Muscimol; Nerve Tissue Proteins; Picrotoxin; Rats; Receptors, GABA-B; Receptors, Purinergic P2; Receptors, Purinergic P2X; Synaptosomes; Time Factors | 2003 |
Endogenous acetylcholine and nicotine activation enhances GABAergic and glycinergic inputs to cardiac vagal neurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Heart; Neostigmine; Neurons; Nicotine; Nicotinic Agonists; Parasympathetic Nervous System; Picrotoxin; Pyridazines; Rats; Strychnine; Synaptic Transmission; Vagus Nerve | 2003 |
Control of bursting by local inhibition in the rat subiculum in vitro.
Topics: Action Potentials; Animals; Cell Size; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Periodicity; Picrotoxin; Potassium; Rats; Rats, Wistar; Synapses | 2003 |
Metabotropic glutamate receptor-mediated hetero-synaptic interaction of red- and green-cone inputs to LHC of carp retina.
Topics: Animals; Aspartic Acid; Carps; Color; D-Aspartic Acid; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Interneurons; Membrane Potentials; Photic Stimulation; Picrotoxin; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells | 2003 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine | 2003 |
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-Acetyltransferase; Disease Models, Animal; Efferent Pathways; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Locomotion; Muscarinic Antagonists; Muscimol; Muscle Tonus; N-Methylaspartate; Neural Inhibition; Picrotoxin; Stimulation, Chemical | 2003 |
RdlDv, a novel GABA-gated chloride channel gene from the American dog tick Dermacentor variabilis.
Topics: Amino Acid Sequence; Animals; Chloride Channels; Cloning, Molecular; Dermacentor; Dieldrin; Dogs; Drosophila Proteins; gamma-Aminobutyric Acid; Insect Proteins; Insecticide Resistance; Ion Channel Gating; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Picrotoxin; Pyrazoles; Receptors, GABA-A; Recombinant Proteins; Sequence Homology, Amino Acid; Sesterterpenes; Xenopus | 2003 |
Beta-alanine acts on glycine receptors in the rat sacral dorsal commissural neurons.
Topics: Animals; Animals, Newborn; beta-Alanine; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Glycine; Strychnine | 2003 |
GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons.
Topics: Animals; Calcium; Calcium Channels; Cell Separation; Cells, Cultured; Chloride Channels; Chlorides; Drosophila; Drosophila Proteins; Embryo, Nonmammalian; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Receptors, GABA; Receptors, GABA-A; Synaptic Transmission; Time Factors | 2003 |
GABA depolarizes neuronal progenitors of the postnatal subventricular zone via GABAA receptor activation.
Topics: Adenosine Triphosphate; Animals; Barbiturates; Benzodiazepines; Cerebral Ventricles; Dose-Response Relationship, Drug; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoenzymes; Membrane Potentials; Mice; Neostriatum; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channels; Receptors, GABA-A; Stem Cells; Zinc | 2003 |
Regional variations in local contributions to the primate photopic flash ERG: revealed using the slow-sequence mfERG.
Topics: Adolescent; Adult; Aminobutyrates; Animals; Drug Combinations; Electroretinography; gamma-Aminobutyric Acid; Humans; Injections; Light; Macaca mulatta; N-Methylaspartate; Photic Stimulation; Picrotoxin; Pipecolic Acids; Retina; Tetrodotoxin | 2003 |
Concerted GABAergic actions of Aplysia feeding interneurons in motor program specification.
Topics: Animals; Aplysia; Feeding Behavior; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Membrane Potentials; Motor Activity; Nerve Net; Neural Inhibition; Picrotoxin | 2003 |
Contribution of GABAergic inhibition to the responses of secondary vestibular neurons to head rotation in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Head; Iontophoresis; Neural Inhibition; Neurons; Picrotoxin; Rats; Reaction Time; Rotation; Vestibular Nerve; Vestibular Nuclei | 2003 |
Taurine activates strychnine-sensitive glycine receptors in neurons freshly isolated from nucleus accumbens of young rats.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Taurine | 2004 |
Modulation of GABAA receptors and neuropeptide secretion by the neurosteroid allopregnanolone in posterior and intermediate pituitary.
Topics: alpha-MSH; Animals; Dose-Response Relationship, Drug; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Male; Nerve Endings; Neuropeptides; Patch-Clamp Techniques; Picrotoxin; Pituitary Gland; Pituitary Gland, Posterior; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors; Vasopressins | 2003 |
The effects of gamma-aminobutyric acid and picrotoxin on the junctional potential and the contraction of crayfish muscle.
Topics: Amino Acids; Animals; Astacoidea; gamma-Aminobutyric Acid; Muscles; Neuromuscular Junction; Picrotoxin | 1959 |
Effects of gamma-aminobutyric acid and picrotoxin on spontaneous activity in the central nervous system of the crayfish.
Topics: Amino Acids; Animals; Astacoidea; Central Nervous System; gamma-Aminobutyric Acid; Picrotoxin | 1960 |
INHIBITORY POSTSYNAPTIC POTENTIALS IN GRASSHOPPER MUSCLE.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Grasshoppers; Inhibitory Postsynaptic Potentials; Insecta; Muscles; Neuromuscular Junction; Physiology; Picrotoxin; Research | 1964 |
ELECTROPHYSIOLOGICAL AND PHARMACOLOGICAL ANALYSIS OF THE EFFECT OF GAMMA-AMINOBUTYRIC ACID AND PICROTOXIN ON THE INHIBITORY MECHANISM OF THE POSTERIOR ADDUCTOR IN LAMELLIBRANCHIATA.
Topics: Aminobutyrates; Animals; Electrophysiology; gamma-Aminobutyric Acid; Mollusca; Muscles; Myography; Pharmacology; Picrotoxin; Research | 1963 |
THE ACTION OF SODIUM 4-HYDROXYBUTYRATE ON SPINAL REFLEXES.
Topics: Aminobutyrates; Anesthesia; Anesthesia, Local; Anesthesiology; Animals; Blood Pressure Determination; Cats; Diaphragm; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraperitoneal; Injections, Intravenous; Meprobamate; Mice; Nervous System Physiological Phenomena; Neuromuscular Junction; Pharmacology; Phrenic Nerve; Picrotoxin; Poultry; Rats; Reflex; Research; Seizures; Sodium; Sodium Oxybate; Spinal Cord; Strychnine; Swine; Toxicology | 1964 |
THE DISTRIBUTION OF GAMMA-AMINOBUTYRIC ACID IN THE MONKEY BRAIN DURING PICROTOXIN-INDUCED SEIZURES.
Topics: Aminobutyrates; Animals; Brain; Brain Chemistry; Chromatography; gamma-Aminobutyric Acid; Glutamates; Haplorhini; Metabolism; Parietal Lobe; Picrotoxin; Research; Seizures; Toxicology | 1964 |
THE PHASE REVERSAL PHENOMENON OF THE GABA-ACTION ON THE HIND GUT OF THE CRAYFISH CAUSED BY THE CHANGE IN THE IONIC COMPOSITION OF THE EXTERNAL MEDIUM.
Topics: Acetylcholine; Alanine; Aminobutyrates; Animals; Aspartic Acid; Astacoidea; Bromides; Calcium; Crustacea; gamma-Aminobutyric Acid; Glutamates; Guanidines; Hydroxybutyrates; Intestines; Iodides; Ions; Muscle Contraction; Muscle, Smooth; Muscles; Nitrates; Pharmacology; Phosphates; Picrotoxin; Research; Sodium; Sodium Chloride; Sulfates; Thiocyanates | 1965 |
[EFFECT OF GAMMA-AMINOBUTYRIC ACID AND PICROTOXIN ON SECHENOV'S INHIBITION].
Topics: Aminobutyrates; Animals; Anura; Brain; Electrophysiological Phenomena; Electrophysiology; gamma-Aminobutyric Acid; Picrotoxin; Research | 1964 |
Synaptic strength between motoneurons and terminals of the dorsolateral funiculus is regulated by GABA receptors in the turtle spinal cord.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Motor Neurons; Muscimol; Picrotoxin; Receptors, GABA; Spinal Cord; Synapses; Synaptic Transmission; Time Factors; Turtles | 2004 |
Taurine and the control of basal hormone release from rat neurohypophysis.
Topics: Animals; Calcium; Chloride Channels; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; In Vitro Techniques; Male; Oxytocin; Picrotoxin; Pituitary Gland, Posterior; Pituitary Hormones; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Taurine; Time Factors; Vasopressins | 2003 |
EXP-1 is an excitatory GABA-gated cation channel.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; Antigens, Protozoan; Barium Compounds; Bicuculline; Caenorhabditis elegans; Cations; Chloride Channels; Chlorides; Cloning, Molecular; Dose-Response Relationship, Drug; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglionic Blockers; Gastrointestinal Tract; Green Fluorescent Proteins; Humans; Ion Channel Gating; Luminescent Proteins; Mecamylamine; Membrane Potentials; Molecular Sequence Data; Muscle Contraction; Muscles; Mutagenesis, Site-Directed; Neuromuscular Junction; Oocytes; Patch-Clamp Techniques; Phylogeny; Picrotoxin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sodium; Transfection; Xenopus laevis | 2003 |
Differential sensitivity of genetically Fast vs. Slow kindling rats strains to GABAergic convulsive agents.
Topics: Animals; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Kindling, Neurologic; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Long-Evans; Rats, Wistar; Species Specificity; Strychnine | 2003 |
GABA neurotransmission in the cerebellar interposed nuclei: involvement in classically conditioned eyeblinks and neuronal activity.
Topics: Animals; Cerebellar Nuclei; Conditioning, Classical; Conditioning, Eyelid; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A; Synaptic Transmission | 2004 |
GABA transmission in the ventral pallidum is not involved in the control of latent inhibition in the rat.
Topics: Amphetamine; Animals; Attention; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Psychological; Dopamine Agents; Efferent Pathways; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Inhibition, Psychological; Locomotion; Male; Muscimol; Neural Inhibition; Nucleus Accumbens; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2003 |
Bicuculline-insensitive GABA-gated Cl- channels in the larval nervous system of the moth Manduca sexta.
Topics: Animals; Bicuculline; Chloride Channels; Chlorides; Drosophila; Drosophila Proteins; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Immunohistochemistry; In Vitro Techniques; Ion Channel Gating; Isoquinolines; Isotopes; Larva; Manduca; Nervous System; Neurons; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Time Factors | 2003 |
Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABA rho 1 receptor.
Topics: Animals; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Kinetics; Oocytes; Patch-Clamp Techniques; Picrotoxin; Pregnanolone; Quercetin; Receptors, GABA-B; Recombinant Proteins; Xenopus laevis | 2004 |
GABAA receptor subunit mRNA expression in cultured embryonic and adult human dorsal root ganglion neurons.
Topics: Aging; Bicuculline; Blotting, Southern; Cells, Cultured; Central Nervous System Stimulants; Drug Interactions; Embryo, Mammalian; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Critically timed ethanol exposure reduces GABAAR function on septal neurons developing in vivo but not in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Body Weight; Cells, Cultured; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Ethanol; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Penicillins; Picrotoxin; Pregnancy; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Septum of Brain; Streptomycin; Time Factors; Triazoles; Up-Regulation; Zinc; Zolpidem | 2004 |
The classical receptive field surround of primate parasol ganglion cells is mediated primarily by a non-GABAergic pathway.
Topics: Action Potentials; Animals; Carbenoxolone; Cobalt; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; In Vitro Techniques; Macaca fascicularis; Macaca nemestrina; Papio; Photic Stimulation; Picrotoxin; Primates; Retina; Retinal Ganglion Cells; Signal Transduction; Sodium Channel Blockers; Synaptic Transmission; Visual Fields | 2004 |
Ligand-gated channels in early mesencephalic neuronal precursors: immunocytochemical and electrophysiological analysis.
Topics: Animals; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Ion Channels; Membrane Potentials; Mesencephalon; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, AMPA; Receptors, GABA-A; Receptors, Glutamate; Time Factors | 2004 |
Motor behavior in rats after separate and combined administration of GABAergic agents into the neostriatum.
Topics: Animals; Avoidance Learning; Bicuculline; Conditioning, Operant; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Motor Activity; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Reflex | 2004 |
Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Bicuculline; Calbindin 2; Calcium; Calcium-Binding Proteins; Cell Count; Cell Size; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Nerve Net; Parvalbumins; Picrotoxin; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Time Factors; Valine | 2004 |
The spinal GABAergic system is a strong modulator of burst frequency in the lamprey locomotor network.
Topics: Algorithms; Animals; Calcium Channel Blockers; Chloride Channels; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lampreys; Locomotion; Models, Neurological; Nerve Net; Phosphinic Acids; Picrotoxin; Potassium Channels, Calcium-Activated; Propanolamines; Pyridazines; Pyridines; Receptors, GABA; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2004 |
GABA in pedunculo pontine tegmentum regulates spontaneous rapid eye movement sleep by acting on GABAA receptors in freely moving rats.
Topics: Animals; Electroencephalography; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Pedunculopontine Tegmental Nucleus; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sleep, REM; Wakefulness | 2004 |
Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane.
Topics: Anesthetics, Inhalation; Animals; Chromatography, Gas; Cyclopropanes; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Isoflurane; Male; Motor Activity; Oocytes; Picrotoxin; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xenon; Xenopus | 2004 |
Functional properties of electrical synapses between inhibitory interneurons of neocortical layer 4.
Topics: Analysis of Variance; Animals; Animals, Newborn; Electric Stimulation; Electrodes; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; In Vitro Techniques; Interneurons; Models, Neurological; Neocortex; Neural Inhibition; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Synapses; Synaptic Transmission; Time Factors; Valine | 2005 |
Coordinated excitatory effect of GABAergic interneurons on three feeding motor programs in the mollusk Clione limacina.
Topics: Animals; Behavior, Animal; Bicuculline; Excitatory Postsynaptic Potentials; Feeding Behavior; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Immunohistochemistry; Interneurons; Mollusca; Motor Neurons; Mouth; Nerve Net; Neural Inhibition; Periodicity; Picrotoxin | 2005 |
Estradiol-induced changes in the activity of hippocampal neurons in network culture are suppressed by co-incubation with gabapentin.
Topics: 2-Amino-5-phosphonovalerate; Amines; Analysis of Variance; Animals; Calcium; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Drug Interactions; Estradiol; Excitatory Amino Acid Antagonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Nerve Net; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Chloride; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Reaction Time; Synaptic Transmission; Time Factors | 2004 |
Characterization of a GABAergic neurotransmission in adult Schistosoma mansoni.
Topics: Animals; Central Nervous System Stimulants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Immunoblotting; Immunohistochemistry; Male; Molecular Weight; Movement; Neurons; Picrotoxin; Schistosoma mansoni; Signal Transduction; Synaptic Transmission | 2004 |
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
Topics: Animals; Bicuculline; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Ionophores; Membrane Potentials; Microscopy, Electron, Transmission; Models, Neurological; Neural Inhibition; Neurons; Nystatin; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Presynaptic Terminals; Pyridines; Quinoxalines; Retina; Time Factors; Valine | 2004 |
Picrotoxin accelerates relaxation of GABAC receptors.
Topics: Animals; Bass; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Picrotoxin; Receptors, GABA; Xenopus laevis | 2005 |
Changes in gamma-aminobutyric acid tone and extracellular serotonin in the dorsal raphe nucleus over the rat estrous cycle.
Topics: Animals; Bicuculline; Brain Chemistry; Estrogens; Estrous Cycle; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Microdialysis; Picrotoxin; Progesterone; Raphe Nuclei; Rats; Rats, Inbred WKY; Serotonin; Sex Factors | 2004 |
GABAergic and glutamatergic inhibition of nonspiking local interneurons in the terminal abdominal ganglion of the crayfish.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Interneurons; Membrane Potentials; Neural Inhibition; Picrotoxin | 2005 |
Presynaptic NMDA autoreceptors facilitate axon excitability: a new molecular target for the anticonvulsant gabapentin.
Topics: Amines; Analysis of Variance; Animals; Anticonvulsants; Axons; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neural Inhibition; Phosphinic Acids; Picrotoxin; Potassium Chloride; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 2005 |
Evidence for a role of the parafascicular nucleus of the thalamus in the control of epileptic seizures by the superior colliculus.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Excitatory Amino Acid Agonists; Extracellular Fluid; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Intralaminar Thalamic Nuclei; Kainic Acid; Male; Microdialysis; Microinjections; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Substantia Nigra; Superior Colliculi | 2005 |
Transmembrane residues define the action of isoflurane at the GABAA receptor alpha-3 subunit.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cell Line; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoflurane; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Picrotoxin; Propofol; Protein Structure, Tertiary; Protein Subunits; Receptors, GABA-A; Transfection | 2005 |
Gestational and postnatal malnutrition affects sensitivity of young rats to picrotoxin and quinolinic acid and uptake of GABA by cortical and hippocampal slices.
Topics: Analysis of Variance; Animals; Animals, Newborn; Body Weight; Caseins; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Fetal Nutrition Disorders; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lactation; Male; Picrotoxin; Pregnancy; Prenatal Nutritional Physiological Phenomena; Quinolinic Acid; Rats; Seizures; Time Factors; Tritium | 2005 |
Distinct roles of glycinergic and GABAergic inhibition in coordinating locomotor-like rhythms in the neonatal mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Motor Activity; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Picrotoxin; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine | 2005 |
Functional characterization of rat rho2 subunits expressed in HEK 293 cells.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Picrotoxin; Rats; Receptors, GABA; Receptors, GABA-A; Xenopus | 2005 |
Effects of sodium nitroprusside, a nitric oxide donor, on gamma-aminobutyric acid concentration in the brain and on picrotoxin-induced convulsions in combination with phenobarbitone in rats.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Combinations; gamma-Aminobutyric Acid; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Phenobarbital; Picrotoxin; Rats; Rats, Wistar; Seizures | 2005 |
Resistance to fipronil in Drosophila simulans: influence of two point mutations in the RDL GABA receptor subunit.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Membrane; Drosophila; Drosophila Proteins; Female; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Insecticide Resistance; Insecticides; Oocytes; Picrotoxin; Point Mutation; Protein Structure, Tertiary; Protein Subunits; Pyrazoles; Receptors, GABA-A; Xenopus | 2005 |
Drosophila mushroom body Kenyon cells generate spontaneous calcium transients mediated by PLTX-sensitive calcium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Analysis of Variance; Animals; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Chlorine; Cobalt; Curare; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drosophila; Drug Combinations; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Iodine; Mushroom Bodies; Neurons; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Phenols; Picrotoxin; Pupa; Salicylates; Spider Venoms; Tetrodotoxin; Thapsigargin; Time Factors; Valine | 2005 |
GABA induces activity dependent delayed-onset uncoupling of GABA/benzodiazepine site interactions in neocortical neurons.
Topics: Amanitins; Animals; Benzodiazepines; Binding Sites; Calcium; Cerebellum; Cerebral Cortex; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Kinetics; Models, Biological; Neurons; Nifedipine; Osmosis; Picrotoxin; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transcription, Genetic; Zolpidem | 2005 |
Taurine activates excitatory non-synaptic glycine receptors on dopamine neurones in ventral tegmental area of young rats.
Topics: Action Potentials; Age Factors; Animals; Bicuculline; Convulsants; Dopamine; gamma-Aminobutyric Acid; Glycine; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, Glycine; Strychnine; Taurine; Ventral Tegmental Area | 2005 |
Feedforward inhibition of projection neurons by fast-spiking GABA interneurons in the rat striatum in vivo.
Topics: Action Potentials; Animals; Biotin; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Fluorescent Antibody Technique; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Interneurons; Neural Inhibition; Neural Pathways; Parvalbumins; Picrotoxin; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2005 |
[The GABA-ergic regulation of the Lymnaea stagnalis (L.) dorsal longitudinal muscle contractions].
Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Lymnaea; Muscle Contraction; Muscles; Nerve Fibers; Picrotoxin | 2005 |
A noncanonical release of GABA and glutamate modulates neuronal migration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Bicuculline; Bromodeoxyuridine; Cell Movement; Dideoxynucleosides; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Immunohistochemistry; In Vitro Techniques; Mice; Mice, Mutant Strains; Mice, Transgenic; Microtubule-Associated Proteins; Munc18 Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2005 |
Pigment-dispersing factor and GABA synchronize cells of the isolated circadian clock of the cockroach Leucophaea maderae.
Topics: Action Potentials; Animals; Calcium; Circadian Rhythm; Cockroaches; GABA Antagonists; gamma-Aminobutyric Acid; Insect Proteins; Male; Medulla Oblongata; Models, Biological; Neural Inhibition; Neurons; Neuropeptides; Picrotoxin; Suprachiasmatic Nucleus | 2005 |
Role of GABA in electro-acupuncture therapy on cerebral ischemia induced by occlusion of the middle cerebral artery in rats.
Topics: Animals; Brain Ischemia; Cell Survival; Cerebral Cortex; Dose-Response Relationship, Drug; Electroacupuncture; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley | 2005 |
Globus pallidus neurons dynamically regulate the activity pattern of subthalamic nucleus neurons through the frequency-dependent activation of postsynaptic GABAA and GABAB receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Lysine; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurons; Parkinson Disease; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Quinoxalines; Receptors, GABA-A; Receptors, GABA-B; Subthalamic Nucleus; Synapses; Tetrodotoxin | 2005 |
Quinolinic acid toxicity on orexin neurons blocked by gamma aminobutyric acid type A receptor stimulation.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Magnesium; Neurons; Neuropeptides; Nipecotic Acids; Norepinephrine; Orexin Receptors; Orexins; Organophosphorus Compounds; Picrotoxin; Quinolinic Acid; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Selective Serotonin Reuptake Inhibitors; Serotonin | 2005 |
Functional interconnectivity between the globus pallidus and the subthalamic nucleus in the mouse brain slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Apamin; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; In Vitro Techniques; Lysine; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Net; Neurons; Picrotoxin; Subthalamic Nucleus | 2005 |
Nicotinic acetylcholine receptor subtypes involved in facilitation of GABAergic inhibition in mouse superficial superior colliculus.
Topics: Acetylcholine; Animals; Bicuculline; Bungarotoxins; Cadmium; Conotoxins; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Isoenzymes; Mecamylamine; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Neural Networks, Computer; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Pyridazines; Receptors, Nicotinic; Superior Colliculi | 2005 |
Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction.
Topics: Acetylcholinesterase; Aconitine; Animals; Animals, Newborn; Antibodies, Monoclonal; Cholinergic Fibers; Denervation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Immunotoxins; In Vitro Techniques; Long-Term Potentiation; N-Glycosyl Hydrolases; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Receptors, Nicotinic; Ribosome Inactivating Proteins, Type 1; Saporins; Valine | 2005 |
GABA modulates Drosophila circadian clock neurons via GABAB receptors and decreases in calcium.
Topics: Animals; Animals, Genetically Modified; Blotting, Western; Calcium; Cell Count; Cells, Cultured; Circadian Rhythm; Diagnostic Imaging; Dose-Response Relationship, Drug; Drosophila; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; Immunohistochemistry; Isoenzymes; Larva; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Serotonin | 2005 |
Repeated cocaine exposure in vivo facilitates LTP induction in midbrain dopamine neurons.
Topics: Animals; Bicuculline; Cocaine; Diazepam; Dopamine; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Male; Memory; Mesencephalon; Neuronal Plasticity; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 2005 |
Analysis of macroscopic ionic currents mediated by GABArho1 receptors during lanthanide modulation predicts novel states controlling channel gating.
Topics: Chloride Channels; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Lanthanoid Series Elements; Phosphinic Acids; Picrotoxin; Protein Subunits; Pyridines; Receptors, GABA | 2005 |
Multiple and plastic receptors mediate tonic GABAA receptor currents in the hippocampus.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Drug Interactions; Epilepsy; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Neuronal Plasticity; Neurons; Nipecotic Acids; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin | 2005 |
Kinetics and spontaneous open probability conferred by the epsilon subunit of the GABAA receptor.
Topics: Cell Line; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Picrotoxin; Probability; Protein Subunits; Receptors, GABA-A; Synaptic Transmission; Time Factors; Transfection | 2005 |
Differential sensitivity of GABAergic and glycinergic inputs to orexin-A in preganglionic cardiac vagal neurons of newborn rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Heart; Intracellular Signaling Peptides and Proteins; Neurons; Neuropeptides; Orexins; Picrotoxin; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vagus Nerve | 2005 |
Mixed antagonistic effects of bilobalide at rho1 GABAC receptor.
Topics: Animals; Chloride Channels; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Female; Furans; GABA Antagonists; gamma-Aminobutyric Acid; Gene Transfer Techniques; Ginkgolides; Humans; Neural Inhibition; Oocytes; Patch-Clamp Techniques; Picrotoxin; Plant Extracts; Protein Subunits; Receptors, GABA; Recombinant Fusion Proteins; Xenopus laevis | 2006 |
GABAergic synaptic transmission modulates swimming in the ascidian larva.
Topics: Animals; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Larva; Motor Activity; Motor Neurons; Muscles; Picrotoxin; Swimming; Synaptic Transmission; Urochordata | 2005 |
Theta bursts set up glutamatergic as well as GABA-ergic plasticity in neonatal rat hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Theta Rhythm | 2006 |
Altered inhibition in lateral amygdala networks in a rat model of temporal lobe epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Matched-Pair Analysis; Nerve Net; Neural Inhibition; Neurons; Parahippocampal Gyrus; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2006 |
GABAergic signaling at mossy fiber synapses in neonatal rat hippocampus.
Topics: Action Potentials; Aminobutyrates; Animals; Animals, Newborn; Bicuculline; Cation Transport Proteins; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Agonists; Flurazepam; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Mossy Fibers, Hippocampal; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, GABA-A; Synaptic Transmission; Vesicular Glutamate Transport Protein 1 | 2006 |
Molecular weight and subunit composition of the sensitive to GABA-ergic ligands Cl-/HCO3(-)-stimulated Mg2+-ATPase from plasma membrane of rat brain.
Topics: Animals; Bicarbonates; Bicuculline; Brain; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Chlorides; Chromatography, Gel; Electrophoresis, Gel, Two-Dimensional; gamma-Aminobutyric Acid; Molecular Weight; Picrotoxin; Protein Subunits; Rats; Receptors, GABA-A | 2005 |
Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Morphine; Muscimol; Narcotics; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time | 2006 |
Enhanced hippocampal GABAergic inhibition in mice overexpressing heparin-binding growth-associated molecule.
Topics: Animals; Carrier Proteins; Cytokines; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Mice; Mice, Transgenic; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Time Factors | 2006 |
Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Apoptosis; Bicuculline; Cell Survival; Cells, Cultured; Cerebellar Cortex; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Histamine; Histamine Agonists; Histamine Antagonists; N-Methylaspartate; Necrosis; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Time Factors | 2006 |
Neuronal electrical high frequency stimulation enhances GABA outflow from human neocortical slices.
Topics: Bicuculline; Chromatography, High Pressure Liquid; Electric Stimulation; Electrochemistry; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Neocortex; Nerve Endings; Neurons; Picrotoxin; Sodium Channel Agonists; Veratridine | 2006 |
Role of noradrenergic and GABA-ergic inputs in pedunculopontine tegmentum for regulation of rapid eye movement sleep in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Choline O-Acetyltransferase; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Male; Mesencephalon; Microinjections; Norepinephrine; Picrotoxin; Polysomnography; Pons; Prazosin; Propranolol; Rats; Rats, Wistar; Sleep, REM; Wakefulness | 2006 |
Random assembly of GABA rho1 and rho2 subunits in the formation of heteromeric GABA(C) receptors.
Topics: Animals; Bass; Cells, Cultured; Female; GABA Antagonists; gamma-Aminobutyric Acid; Oocytes; Patch-Clamp Techniques; Picrotoxin; Protein Structure, Quaternary; Protein Subunits; Receptors, GABA; Retinal Bipolar Cells; Xenopus laevis | 2006 |
Cross-inhibitory interactions between GABAA and P2X channels in myenteric neurones.
Topics: Adenosine Triphosphate; Animals; Calcium; Female; GABA Antagonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guinea Pigs; Male; Myenteric Plexus; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridoxal Phosphate; Receptors, GABA-A; Receptors, Purinergic P2; Receptors, Purinergic P2X | 2006 |
Tonic and phasic differential GABAergic inhibition of synaptic actions of joint afferents in the cat.
Topics: Animals; Cats; Electric Stimulation; Evoked Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Joints; Male; Muscle, Skeletal; Neurons, Afferent; Picrotoxin; Skin; Spinal Cord; Synapses | 2007 |
Evidence that the beta-acids fraction of hops reduces central GABAergic neurotransmission.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Carbon Dioxide; Central Nervous System; Cerebellum; Depression, Chemical; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Humulus; Male; Maze Learning; Motor Activity; Pentobarbital; Picrotoxin; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sleep; Solvents; Swimming; Synaptic Transmission | 2007 |
In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism.
Topics: Action Potentials; Aminopyridines; Animals; Brain Chemistry; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Indoles; Male; Neural Inhibition; Neurons; Picrotoxin; Piperazines; Positron-Emission Tomography; Proto-Oncogene Proteins c-fos; Pyrazines; Pyridines; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Ritanserin; Serotonin | 2006 |
Role of GABAergic antagonism in the neuroprotective effects of bilobalide.
Topics: Animals; Area Under Curve; Bicuculline; Brain Edema; Bridged Bicyclo Compounds, Heterocyclic; Choline; Cyclopentanes; Drug Interactions; Excitatory Amino Acid Agonists; Furans; GABA Antagonists; gamma-Aminobutyric Acid; Ginkgolides; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuroprotective Agents; Nonlinear Dynamics; Picrotoxin; Rats; Rats, Sprague-Dawley; Synaptosomes | 2007 |
Functional characterization of Musca glutamate- and GABA-gated chloride channels expressed independently and coexpressed in Xenopus oocytes.
Topics: Animals; Antiparasitic Agents; Chloride Channel Agonists; Chloride Channels; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Glutamates; Hexachlorocyclohexane; Ion Channel Gating; Muscidae; Oocytes; Picrotoxin; Protein Structure, Quaternary; Pyrazoles; RNA, Complementary; Sesterterpenes; Xenopus laevis | 2006 |
GABA excitation in mouse hilar neuropeptide Y neurons.
Topics: Animals; Bicuculline; Evoked Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Interneurons; Membrane Potentials; Mice; Mice, Transgenic; Neuropeptide Y; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Somatostatin | 2007 |
The location of a closed channel gate in the GABAA receptor channel.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Cysteine; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Membrane Potentials; Microinjections; Mutation; Oocytes; Patch-Clamp Techniques; Penicillins; Picrotoxin; Protein Conformation; Rats; Receptors, GABA-A; Xenopus laevis | 2007 |
Contextual interaction of GABAergic circuitry with dynamic synapses.
Topics: Algorithms; Animals; Bicuculline; Brain Mapping; Chickens; Chloride Channels; Data Interpretation, Statistical; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Nerve Net; Photic Stimulation; Picrotoxin; Poisson Distribution; Retina; Superior Colliculi; Synapses; Visual Pathways | 2007 |
Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors.
Topics: Amygdala; Analysis of Variance; Anesthetics; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2007 |
GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Bicuculline; Cyclopropanes; Enkephalin, Methionine; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Interneurons; Male; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Muscimol; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Pyridazines; Pyridinium Compounds; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin | 2007 |
In the developing rat hippocampus a tonic GABAA-mediated conductance selectively enhances the glutamatergic drive of principal cells.
Topics: Animals; Animals, Newborn; Electric Stimulation; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamine; Hippocampus; In Vitro Techniques; Interneurons; Membrane Potentials; Neural Inhibition; Neuronal Plasticity; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission; Time Factors | 2007 |
Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1beta2gamma2S subunits of GABA (A) receptors.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Cell Line; Diazepam; Flumazenil; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Muscimol; Picrotoxin; Protein Subunits; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Receptors, GABA-B; Transfection; Up-Regulation | 2007 |
Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities.
Topics: Action Potentials; Animals; beta-Alanine; Bicuculline; Crotonates; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Furosemide; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Imidazoles; Microinjections; Mutation; Neural Inhibition; Neurons; Oocytes; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Sesterterpenes; Taurine; Xenopus laevis; Zinc | 2007 |
Respiratory activity in brainstem of fetal mice lacking glutamate decarboxylase 65/67 and vesicular GABA transporter.
Topics: Animals; Brain Stem; Electrophysiology; Female; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine; Glycine Agents; Isoenzymes; Medulla Oblongata; Mice; Mice, Knockout; Oxygen Consumption; Picrotoxin; Pregnancy; Spinal Cord; Spinal Nerve Roots; Strychnine; Substance P; Vesicular Inhibitory Amino Acid Transport Proteins | 2007 |
Novel stimulus-induced calcium efflux in Drosophila mushroom bodies.
Topics: Animals; Animals, Genetically Modified; Calcium; Calcium Signaling; Drosophila melanogaster; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Mushroom Bodies; Nicotine; Nicotinic Agonists; Picrotoxin; Receptors, GABA; Sodium-Calcium Exchanger | 2007 |
Optical suppression of seizure-like activity with an LED.
Topics: Animals; Anticonvulsants; Calcium; Cells, Cultured; Electrophysiology; Epilepsies, Partial; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Mice; Microscopy, Fluorescence; Neurons; Picrotoxin; Seizures; Ultraviolet Rays | 2007 |
Dual GABAA receptor-mediated inhibition in rat presympathetic paraventricular nucleus neurons.
Topics: Animals; Bicuculline; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Medulla Oblongata; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Synapses | 2007 |
GABA (A) receptor subunits RNA expression in mice peritoneal macrophages modulate their IL-6/IL-12 production.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Interleukin-12; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred BALB C; Peritoneum; Picrotoxin; Protein Subunits; Receptors, GABA-A; RNA, Messenger | 2007 |
D2 dopamine receptors recruit a GABA component for their attenuation of excitatory synaptic transmission in the adult rat prefrontal cortex.
Topics: Animals; Animals, Newborn; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Quinpirole; Rats; Receptors, Dopamine D2; Salicylamides; Synaptic Transmission | 2007 |
Regional differences in GABAergic modulation for TEA-induced synaptic plasticity in rat hippocampal CA1, CA3 and dentate gyrus.
Topics: Animals; Dentate Gyrus; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Long-Term Potentiation; Male; Mossy Fibers, Hippocampal; Neuronal Plasticity; Nickel; Organ Culture Techniques; Perforant Pathway; Picrotoxin; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Synaptic Transmission; Tetraethylammonium | 2007 |
NF-kappaB activity in distinct neural subtypes of the rat hippocampus: Influence of time and GABA antagonism in acute slice preparations.
Topics: Animals; Cell Nucleus; Cytosol; Dentate Gyrus; GABA Antagonists; gamma-Aminobutyric Acid; I-kappa B Proteins; Long-Term Potentiation; Male; Memory; Neural Cell Adhesion Molecule L1; Neuronal Plasticity; NF-kappa B; NF-KappaB Inhibitor alpha; Organ Culture Techniques; Picrotoxin; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Sialic Acids | 2007 |
Alpha5GABAA receptors regulate the intrinsic excitability of mouse hippocampal pyramidal neurons.
Topics: Action Potentials; Animals; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Imidazoles; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Receptors, GABA-A | 2007 |
High-frequency afferent stimulation induces long-term potentiation of field potentials in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Animals, Newborn; Baclofen; Dopamine; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2008 |
CD4(+)CD25(-) effector T-cells inhibit hippocampal long-term potentiation in vitro.
Topics: Animals; CD4-Positive T-Lymphocytes; Cytokines; Electric Stimulation; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; In Vitro Techniques; Inflammation; Interleukin-2 Receptor alpha Subunit; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Picrotoxin; Synapses | 2007 |
GABAergic neurosteroids mediate the effects of ethanol on long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 20-alpha-Dihydroprogesterone; Animals; Animals, Newborn; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Picrotoxin; Rats; Rats, Sprague-Dawley | 2007 |
Characteristics of GABA receptors on the ocellar L-neurons of American cockroach Periplaneta americana.
Topics: Animals; Bicuculline; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Membrane Potentials; Muscimol; Neurons; Periplaneta; Picrotoxin; Receptors, GABA; Sodium Chloride | 2007 |
Possible involvement of GABAergic modulation in the protective effect of gabapentin against immobilization stress-induced behavior alterations and oxidative damage in mice.
Topics: Amines; Animals; Behavior, Animal; Catalase; Cyclohexanecarboxylic Acids; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Glutathione; Immobilization; Mice; Motor Activity; Muscimol; Oxidation-Reduction; Picrotoxin; Stress, Psychological | 2007 |
Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin.
Topics: Analysis of Variance; Animals; Behavior, Animal; Chromatography, Liquid; Disease Models, Animal; Dopamine; Electroencephalography; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Methoxyhydroxyphenylglycol; Microdialysis; Picrotoxin; Pilocarpine; Rats; Rats, Wistar; Seizures; Serotonin; Statistics, Nonparametric; Time Factors | 2008 |
Oxytocin-induced postinhibitory rebound firing facilitates bursting activity in oxytocin neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Inhibition; Neurons; Nickel; Ornipressin; Oxytocin; Picrotoxin; Pyrimidines; Rats; Rats, Wistar; Time Factors; Up-Regulation | 2008 |
Sedative and anticonvulsant effects of zolpidem in adult and aged mice.
Topics: Age Factors; Animals; Anticonvulsants; Brain; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Epilepsy; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred CBA; Motor Activity; Pentylenetetrazole; Picrotoxin; Pyridines; Zolpidem | 2008 |
Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cyanobacteria; Diltiazem; Female; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Intracellular Signaling Peptides and Proteins; Lidocaine; Membrane Potentials; Mice; Molecular Sequence Data; Mutation; Ondansetron; Oocytes; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-B; Receptors, Serotonin, 5-HT3; Sequence Homology, Amino Acid; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Sodium Chloride; Xenopus laevis | 2008 |
Anticonvulsant characteristics of pyridoxyl-gamma-aminobutyrate, PL-GABA.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Drug Tolerance; Electrophysiology; Electroshock; Enzyme Inhibitors; Epilepsy; gamma-Aminobutyric Acid; Gerbillinae; Magnesium; Male; Mice; Mice, Inbred BALB C; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Seizures; Tissue Distribution | 2008 |
Developmental downregulation of GABAergic drive parallels formation of functional synapses in cultured mouse neocortical networks.
Topics: Animals; Bicuculline; Cells, Cultured; Dose-Response Relationship, Radiation; Down-Regulation; Electric Stimulation; Embryo, Mammalian; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; Interneurons; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Nerve Net; Nerve Tissue Proteins; Patch-Clamp Techniques; Picrotoxin; Synapses; Synaptic Transmission; Time Factors | 2008 |
Activation of A-type gamma-amino butyric acid receptors excites gonadotrophin-releasing hormone neurones isolated from adult rats.
Topics: Action Potentials; Age Factors; Animals; Animals, Genetically Modified; Cell Culture Techniques; Cells, Cultured; Electrophysiology; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Male; Neurons; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Steroids | 2008 |
Gabapentin attenuates acute hypoxic stress-induced behavioral alterations and oxidative damage in mice: possible involvement of GABAergic mechanism.
Topics: Amines; Analysis of Variance; Animals; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hypoxia; Lipid Peroxidation; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Spectrophotometry | 2008 |
Agonist- and antagonist-induced conformational changes of loop F and their contributions to the rho1 GABA receptor function.
Topics: Amino Acid Sequence; Animals; Cysteine; Female; Fluorescent Dyes; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Picrotoxin; Protein Conformation; Protein Subunits; Receptors, GABA-B; Recombinant Proteins; Xenopus laevis | 2009 |
Chloride accumulation drives volume dynamics underlying cell proliferation and migration.
Topics: Acetates; Analysis of Variance; Bumetanide; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Size; Chlorides; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glioblastoma; Green Fluorescent Proteins; Humans; Imaging, Three-Dimensional; Indenes; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Sodium Potassium Chloride Symporter Inhibitors; Transfection | 2009 |
Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Fluorometry; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Conformation; Rats; Receptors, GABA-A; Rhodamines; Xenopus laevis | 2009 |
GABA(A)- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Brain; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Lymnaea; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Picrotoxin; Receptors, AMPA; Receptors, GABA-A; Respiration | 2009 |
PTX-induced hyperexcitability affects dendritic shape and GABAergic synapse density but not synapse distribution during Manduca postembryonic motoneuron development.
Topics: Action Potentials; Animals; Chloride Channels; Dendrites; Flight, Animal; gamma-Aminobutyric Acid; Image Processing, Computer-Assisted; Manduca; Metamorphosis, Biological; Microscopy, Confocal; Motor Neurons; Picrotoxin; Pupa; Reflex; Synapses | 2009 |
GABAergic/glutamatergic-glial/neuronal interaction contributes to rapid adaptation in pacinian corpuscles.
Topics: Action Potentials; Adaptation, Physiological; Animals; Cats; DNA; DNA Primers; Electrophysiology; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Neuroglia; Neurons; Pacinian Corpuscles; Picrotoxin; Pyridazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Propofol produces immobility via action in the ventral horn of the spinal cord by a GABAergic mechanism.
Topics: Action Potentials; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anterior Horn Cells; Decerebrate State; GABA Antagonists; gamma-Aminobutyric Acid; Immobilization; Isoflurane; Male; Movement; Pain Threshold; Picrotoxin; Posterior Horn Cells; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2009 |
Spontaneous activity in the developing mouse midbrain driven by an external pacemaker.
Topics: Action Potentials; Age Factors; Animals; Bicuculline; Calcium; Choline O-Acetyltransferase; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Image Processing, Computer-Assisted; Immunohistochemistry; Mesencephalon; Mice; Nerve Net; Neurons; Picrotoxin; Rhombencephalon; Serotonin; Tyrosine 3-Monooxygenase | 2009 |
The tuberal lateral hypothalamus is a major target for GABAA--but not GABAB-mediated control of food intake.
Topics: Animals; Appetite Regulation; Feeding Behavior; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2009 |
A rodent model of schizophrenia derived from postmortem studies.
Topics: Amygdala; Animals; Disease Models, Animal; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Inhibitory Postsynaptic Potentials; Interneurons; Neural Pathways; Neuronal Plasticity; Neurons; Picrotoxin; Rats; Receptors, GABA-A; Schizophrenia | 2009 |
Odor-evoked neural oscillations in Drosophila are mediated by widely branching interneurons.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Biological Clocks; Biotin; Drosophila; Drosophila Proteins; Dynamins; Evoked Potentials; Food; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Interneurons; Membrane Potentials; Mushroom Bodies; Nerve Tissue Proteins; Neural Pathways; Odorants; Picrotoxin; Temperature; Transcription Factors | 2009 |
Synchronization of GABAergic inputs to CA3 pyramidal cells precedes seizure-like event onset in juvenile rat hippocampal slices.
Topics: Aging; Animals; CA3 Region, Hippocampal; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Intracellular Space; Magnesium Deficiency; Male; Periodicity; Picrotoxin; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Seizures; Synapses; Synaptic Transmission; Time Factors | 2009 |
GABA in pedunculopontine tegmentum increases rapid eye movement sleep in freely moving rats: possible role of GABA-ergic inputs from substantia nigra pars reticulata.
Topics: Animals; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Wistar; Sleep, REM; Substantia Nigra; Tegmentum Mesencephali; Wakefulness | 2009 |
Site-specific fluorescence reveals distinct structural changes induced in the human rho 1 GABA receptor by inhibitory neurosteroids.
Topics: Dose-Response Relationship, Drug; Estradiol; Fluorescence; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mutation; Neurotransmitter Agents; Picrotoxin; Protein Conformation; Receptors, GABA-B; Sesterterpenes | 2010 |
Diphenyl diselenide-induced seizures in rat pups: possible interaction with GABAergic system.
Topics: Acetanilides; Animals; Animals, Newborn; Benzene Derivatives; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; GABA Modulators; gamma-Aminobutyric Acid; Organoselenium Compounds; Phenobarbital; Picrotoxin; Rats; Seizures | 2010 |
Pre- and postsynaptic modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord.
Topics: Animals; Bicuculline; Furosemide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Motor Neurons; Picrotoxin; Presynaptic Terminals; Pyridazines; Receptors, GABA-A; Reflex, Monosynaptic; Spinal Cord; Synaptic Potentials; Turtles | 2010 |
Long-lasting intrinsic optical changes observed in the neurointermediate lobe of the mouse pituitary reflect volume changes in cells of the pars intermedia.
Topics: Action Potentials; Animals; Bicuculline; Calcium; Female; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Picrotoxin; Pituitary Gland, Intermediate; Receptors, GABA-A | 2010 |
Pharmacological characterization of GABAA receptors in taurine-fed mice.
Topics: Animals; Behavior, Animal; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Mice; Picrotoxin; Receptors, GABA-A; Seizures; Taurine | 2010 |
GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity.
Topics: Animals; Connexins; Electroencephalography; Electrophysiological Phenomena; Etomidate; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junction delta-2 Protein; Gap Junctions; Hypnotics and Sedatives; In Vitro Techniques; Magnesium Deficiency; Male; Mefloquine; Mice; Mice, Inbred C57BL; Mice, Knockout; Picrotoxin; Receptors, GABA-A; Seizures | 2010 |
Facilitation of the inhibitory transmission by gastrin-releasing peptide in the anterior cingulate cortex.
Topics: Action Potentials; Amygdala; Animals; Bombesin; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Gastrin-Releasing Peptide; Glutamates; Gyrus Cinguli; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Mice, Inbred C57BL; Neural Inhibition; Peptide Fragments; Picrotoxin; Pyramidal Cells; Receptors, Bombesin; Synaptic Transmission | 2010 |
Direct and indirect control of orexin/hypocretin neurons by glycine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Alanine; Animals; Animals, Newborn; Benzothiadiazines; Chloride Channels; Electrophysiological Phenomena; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hypothalamus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, Glutamate; Receptors, Glycine; Strychnine; Synaptic Potentials | 2011 |
Sex-specificity of associative learning-induced changes in GABAergic tonic inhibition in layer 4 neurons of mouse barrel cortex.
Topics: Animals; Association Learning; Electrophysiological Phenomena; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Interneurons; Isoxazoles; Male; Mice; Neural Conduction; Neurons; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Sex Characteristics; Somatosensory Cortex | 2011 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; Melatonin; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Sleep Deprivation | 2011 |
The mechanisms of the strong inhibitory modulation of long-term potentiation in the rat dentate gyrus.
Topics: Animals; Dentate Gyrus; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Male; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 2011 |
Cocaine withdrawal reduces group I mGluR-mediated long-term potentiation via decreased GABAergic transmission in the amygdala.
Topics: Amygdala; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synaptic Transmission | 2011 |
[The influence of GABAA receptor on the analgesic action of intrathecally injected oxysophoridine].
Topics: Alkaloids; Analgesics; Animals; Bicuculline; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Muscimol; Pain Threshold; Picrotoxin; Random Allocation; Receptors, GABA-A; Spinal Cord | 2011 |
Bull sperm acrosome reaction induced by gamma-aminobutyric acid (GABA) is mediated by GABAergic receptors type A.
Topics: Acrosome Reaction; Animals; Bicuculline; Calcium Channel Blockers; Cattle; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin; Progesterone; Receptors, GABA-A; Spermatozoa | 2011 |
Reduced hippocampal GABAergic function in Wistar audiogenic rats.
Topics: Animals; CA1 Region, Hippocampal; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 2011 |
Identification of minimal neuronal networks involved in flexor-extensor alternation in the mammalian spinal cord.
Topics: Action Potentials; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glycine Agents; Interneurons; Mice; Mice, Knockout; Motor Activity; Motor Neurons; Muscle Contraction; Muscle, Skeletal; Nerve Net; Periodicity; Picrotoxin; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Strychnine; Synaptic Transmission; Vesicular Glutamate Transport Protein 2 | 2011 |
A diversity of synaptic filters are created by temporal summation of excitation and inhibition.
Topics: Action Potentials; Analysis of Variance; Animals; Axons; Biophysics; Dendrites; Electric Fish; Electric Organ; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Models, Neurological; Movement; Neural Inhibition; Neural Pathways; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Synaptic Potentials | 2011 |
Pharmacological characterization of the Haemonchus contortus GABA-gated chloride channel, Hco-UNC-49: modulation by macrocyclic lactone anthelmintics and a receptor for piperazine.
Topics: Animals; Anthelmintics; Chloride Channels; gamma-Aminobutyric Acid; Gene Expression Regulation; Haemonchus; Helminth Proteins; Insecticides; Ion Channel Gating; Ivermectin; Lactams, Macrocyclic; Macrolides; Oocytes; Picrotoxin; Piperazine; Piperazines; Pyrazoles; Receptors, Cell Surface; Xenopus laevis | 2012 |
Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization.
Topics: Bicuculline; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; HEK293 Cells; Humans; Ion Channel Gating; Mutation; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Receptors, Serotonin, 5-HT3 | 2012 |
Characterization of the picrotoxin site of GABAA receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; gamma-Aminobutyric Acid; Kinetics; Membranes; Nitriles; Picrotoxin; Radioligand Assay; Rats; Receptors, GABA-A; Specimen Handling; Statistics as Topic; Sulfur Radioisotopes | 2001 |
Phasic GABAA -receptor activation is required to suppress epileptiform activity in the CA3 region of the immature rat hippocampus.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Biophysical Phenomena; CA3 Region, Hippocampal; Convulsants; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Oxysophoridine through intrathecal injection induces antinociception and increases the expression of the GABAAα1 receptor in the spinal cord of mice.
Topics: Alkaloids; Analgesics; Animals; Bicuculline; Drug Evaluation, Preclinical; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Mice; Mice, Inbred ICR; Muscimol; Pain Measurement; Picrotoxin; Receptors, GABA-A; Spinal Cord | 2012 |
Activity-dependent alternative splicing increases persistent sodium current and promotes seizure.
Topics: Alternative Splicing; Animals; Drosophila Proteins; Exons; gamma-Aminobutyric Acid; Membrane Potentials; Molecular Sequence Data; Mutant Proteins; Phenytoin; Picrotoxin; Ribonucleoproteins; Seizures; Sodium Channels; Synaptic Transmission | 2012 |
Combination of valproate and paroxetine in mice exposed to picrotoxin.
Topics: Animals; Anticonvulsants; Brain Chemistry; Drug Combinations; gamma-Aminobutyric Acid; Mice; Nucleus Accumbens; Paroxetine; Picrotoxin; Seizures; Selective Serotonin Reuptake Inhibitors; Thiobarbituric Acid Reactive Substances; Valproic Acid | 2012 |
Chloride currents in cones modify feedback from horizontal cells to cones in goldfish retina.
Topics: Action Potentials; Animals; Chloride Channels; Chlorine; Feedback, Physiological; GABA Antagonists; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Goldfish; Models, Neurological; Picrotoxin; Retinal Cone Photoreceptor Cells; Retinal Horizontal Cells; Synaptic Transmission | 2012 |
Evidence for a role of GABA- and glutamate-gated chloride channels in olfactory memory.
Topics: Animals; Bees; Chloride Channels; Conditioning, Psychological; Dicarboxylic Acids; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Ion Channel Gating; Learning; Memory; Mushroom Bodies; Neurotransmitter Uptake Inhibitors; Odorants; Picrotoxin; Pyrrolidines; Smell | 2012 |
OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Long-Term Potentiation; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Picrotoxin; Plant Lectins; Receptors, Nicotinic; RNA, Messenger; Valine; Voltage-Sensitive Dye Imaging | 2012 |
Release of a single neurotransmitter from an identified interneuron coherently affects motor output on multiple time scales.
Topics: Animals; Aplysia; Baclofen; Eating; Excitatory Postsynaptic Potentials; Feeding Behavior; GABA Antagonists; GABA-B Receptor Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Interneurons; Motor Activity; Picrotoxin; Time Factors | 2013 |
Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A.
Topics: Air Pollutants, Occupational; Amygdala; Animals; Anxiety; Benzhydryl Compounds; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Evoked Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; In Vitro Techniques; Indolizines; Male; Methionine; Neural Inhibition; Neurons; Phenols; Picrotoxin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2013 |
Anticonvulsant activity of Hypericum scabrum L.; possible mechanism involved.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; gamma-Aminobutyric Acid; Hypericum; Male; Medicine, Traditional; Mice; Nitric Oxide; Pentylenetetrazole; Picrotoxin; Plant Extracts; Seizures; Time Factors | 2013 |
Emergence of GABAergic-dependent regulation of input-specific plasticity in the adult rat prefrontal cortex during adolescence.
Topics: Animals; Basolateral Nuclear Complex; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Microelectrodes; Neural Pathways; Picrotoxin; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 2014 |
Neurosteroid Agonist at GABAA receptor induces persistent neuroplasticity in VTA dopamine neurons.
Topics: Action Potentials; Animals; Dopamine; Dopaminergic Neurons; Excitatory Amino Acid Agents; Female; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Neurotransmitter Agents; Picrotoxin; Pregnanolone; Receptors, GABA-A; Ventral Tegmental Area | 2014 |
GABA-mimetic actions of Withania somnifera on substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Chloride Channels; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Facial Pain; Female; GABA-A Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Male; Mice; Patch-Clamp Techniques; Phytotherapy; Picrotoxin; Plant Extracts; Receptors, GABA-A; Strychnine; Substantia Gelatinosa; Tetrodotoxin; Trigeminal Nuclei; Withania | 2013 |
GABA-induced uncoupling of GABA/benzodiazepine site interactions is mediated by increased GABAA receptor internalization and associated with a change in subunit composition.
Topics: Animals; Benzodiazepines; Binding Sites; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression Regulation; Neurons; Picrotoxin; Protein Binding; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors; Tritium | 2014 |
Linking γ-aminobutyric acid A receptor to epidermal growth factor receptor pathways activation in human prostate cancer.
Topics: Autocrine Communication; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Isonicotinic Acids; Male; Paracrine Communication; Phosphorylation; Picrotoxin; Prostate; Prostatic Neoplasms; Protein Kinase Inhibitors; Quinazolines; Receptors, GABA-A; Signal Transduction; src-Family Kinases | 2014 |
The novel isoxazoline ectoparasiticide fluralaner: selective inhibition of arthropod γ-aminobutyric acid- and L-glutamate-gated chloride channels and insecticidal/acaricidal activity.
Topics: Amino Acid Sequence; Animals; Chloride Channels; Cloning, Molecular; Ctenocephalides; Dieldrin; DNA, Complementary; Drosophila melanogaster; GABA Antagonists; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Insect Proteins; Insecticides; Isoxazoles; Molecular Sequence Data; Phylogeny; Picrotoxin; Pyrazoles; Rhipicephalus; Sequence Alignment; Sesterterpenes; Xenopus laevis | 2014 |
Can Down syndrome be treated?
Topics: Adult; Animals; Brain; Child; Chromosomes, Human, Pair 21; Clinical Trials as Topic; Cognition Disorders; Down Syndrome; Early Medical Intervention; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Mice; Mutagenesis, Insertional; Picrotoxin; RNA, Long Noncoding | 2014 |
Honeybee Kenyon cells are regulated by a tonic GABA receptor conductance.
Topics: Animals; Bees; Brain; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Mushroom Bodies; Neural Inhibition; Neurons; Picrotoxin; Receptors, GABA | 2014 |
GABA protects pancreatic beta cells against apoptosis by increasing SIRT1 expression and activity.
Topics: Animals; Apoptosis; Baclofen; Cell Line, Tumor; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Insulin-Secreting Cells; Muscimol; NAD; Picrotoxin; Primary Cell Culture; Rats; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; Sirtuin 1; Transcription Factor RelA | 2014 |
Phenylalanine in the pore of the Erwinia ligand-gated ion channel modulates picrotoxinin potency but not receptor function.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Binding, Competitive; Cysteine Loop Ligand-Gated Ion Channel Receptors; Erwinia; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Oocytes; Phenylalanine; Picrotoxin; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sesterterpenes; Xenopus laevis | 2014 |
High-frequency electrical stimulation suppresses cholinergic accumbens interneurons in acute rat brain slices through GABA(B) receptors.
Topics: Acetylcholine; Action Potentials; Animals; Bicuculline; Cholinergic Neurons; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Interneurons; Male; Nucleus Accumbens; Picrotoxin; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, Muscarinic; Small-Conductance Calcium-Activated Potassium Channels; Tissue Culture Techniques | 2014 |
A corticothalamic switch: controlling the thalamus with dynamic synapses.
Topics: Animals; Bacterial Proteins; Central Nervous System Stimulants; Channelrhodopsins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Luminescent Proteins; Mice; Mice, Inbred ICR; Mice, Transgenic; N-Methylaspartate; Neural Pathways; Optogenetics; Picrotoxin; Receptors, Neurotensin; Somatosensory Cortex; Synapses; Thalamus; Valine | 2015 |
Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells.
Topics: Animals; Biophysics; Electric Stimulation; Etomidate; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Picrotoxin; Receptors, GABA-A | 2015 |
Bud extracts from Tilia tomentosa Moench inhibit hippocampal neuronal firing through GABAA and benzodiazepine receptors activation.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Plant Extracts; Receptors, GABA-A; Tilia | 2015 |
Phytochemical analysis and effects of Pteris vittata extract on visual processes.
Topics: Animals; Chick Embryo; Chromatography, Liquid; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Kynurenic Acid; Light; Mass Spectrometry; Phytochemicals; Picrotoxin; Plant Extracts; Pteris; Rana catesbeiana; Retina; Rhodopsin; Vision, Ocular | 2016 |
Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds.
Topics: 4-Aminopyridine; Adult; Amines; Animals; Anticonvulsants; Antipain; Calcium; Calmodulin; Central Nervous System; Convulsants; Cyclohexanecarboxylic Acids; Dipyridamole; Drosophila melanogaster; Drosophila Proteins; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Larva; Male; Molecular Imaging; Motor Neurons; Phenytoin; Picrotoxin; Primary Cell Culture; Sodium Channels | 2016 |
Unexpected Photo-instability of 2,6-Sulfonamide-Substituted BODIPYs and Its Application to Caged GABA.
Topics: Acetaldehyde; Animals; Baclofen; Basolateral Nuclear Complex; Boron Compounds; Formaldehyde; GABA Antagonists; gamma-Aminobutyric Acid; HeLa Cells; Humans; Light; Methylamines; Mice; Picrotoxin; Sulfonamides | 2016 |
Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency.
Topics: Adrenalectomy; Animals; Antipsychotic Agents; Castration; Diazepam; Dioxanes; Dioxoles; Dopamine; Fluvoxamine; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Norepinephrine; Nucleus Accumbens; Orchiectomy; Phenazocine; Picrotoxin; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Receptor, Serotonin, 5-HT1A; Receptors, GABA; Receptors, GABA-A; Receptors, sigma; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Sigma-1 Receptor; Synaptic Transmission; Ventral Tegmental Area | 2016 |
Disinhibition of the rat prelimbic cortex promotes serotonergic activation of the dorsal raphe nucleus and panicolytic-like behavioral effects.
Topics: Animals; Anxiety; Anxiety Disorders; Behavior, Animal; Dorsal Raphe Nucleus; Escape Reaction; gamma-Aminobutyric Acid; Male; Panic; Panic Disorder; Periaqueductal Gray; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonin | 2017 |
Developmental control of spike-timing-dependent plasticity by tonic GABAergic signaling in striatum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Biophysics; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Patch-Clamp Techniques; Picrotoxin; Rats; Signal Transduction | 2017 |
A Population of Projection Neurons that Inhibits the Lateral Horn but Excites the Antennal Lobe through Chemical Synapses in
Topics: Action Potentials; Animals; Animals, Genetically Modified; Cadmium Chloride; Drosophila; Drosophila Proteins; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Luminescent Proteins; Mushroom Bodies; Neural Inhibition; Odorants; Olfactory Bulb; Olfactory Receptor Neurons; Picrotoxin; RNA Interference; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2017 |
A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
Topics: Animals; Bacterial Proteins; Cell Membrane; Chlorides; Etomidate; Extracellular Space; gamma-Aminobutyric Acid; Humans; Ligand-Gated Ion Channels; Membrane Potentials; Mutation; Neurotransmitter Agents; Oocytes; Pentobarbital; Picrotoxin; Propofol; Protein Domains; Protons; Receptors, GABA-B; Recombinant Fusion Proteins; Xenopus laevis | 2017 |
The neurobiological bases of autism spectrum disorders: the R451C-neuroligin 3 mutation hampers the expression of long-term synaptic depression in the dorsal striatum.
Topics: Animals; Autism Spectrum Disorder; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Electroencephalography; Endocannabinoids; Excitatory Postsynaptic Potentials; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Long-Term Synaptic Depression; Male; Membrane Proteins; Mice; Mice, Transgenic; Neostriatum; Nerve Tissue Proteins; Patch-Clamp Techniques; Picrotoxin; Receptor, Cannabinoid, CB1 | 2018 |
Ablation of C-fibers decreases quantal size of GABAergic synaptic transmission in the insular cortex.
Topics: Action Potentials; Animals; Animals, Newborn; Capsaicin; Cerebral Cortex; Cornea; Excitatory Amino Acid Antagonists; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Luminescent Proteins; Nerve Fibers, Unmyelinated; Picrotoxin; Quinoxalines; Rats; Rats, Transgenic; Synaptic Potentials; Synaptic Transmission; Trigeminal Ganglion; Vesicular Inhibitory Amino Acid Transport Proteins | 2017 |
Single-unit Activity in the in vitro Entorhinal Cortex During Carbachol-induced Field Oscillations.
Topics: Action Potentials; Animals; Brain Waves; Carbachol; Cholinergic Agonists; Entorhinal Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurons; Picrotoxin; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Culture Techniques | 2018 |
Gelsedine-type alkaloids: Discovery of natural neurotoxins presented in toxic honey.
Topics: Animals; Antidotes; Biological Availability; Female; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Glucuronides; Honey; Hydroxylation; Indole Alkaloids; Lethal Dose 50; Male; Mice, Inbred ICR; Neurotoxins; Picrotoxin; Rats, Sprague-Dawley | 2020 |
Auditory DUM neurons in a bush-cricket: inhibited inhibitors.
Topics: Acoustic Stimulation; Animals; Auditory Pathways; Auditory Perception; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Gryllidae; Inhibitory Postsynaptic Potentials; Male; Neurons; Picrotoxin | 2020 |
Electrical coupling controls dimensionality and chaotic firing of inferior olive neurons.
Topics: Action Potentials; Animals; Bayes Theorem; Cerebellum; Computer Simulation; Female; gamma-Aminobutyric Acid; Gap Junctions; Models, Neurological; Models, Statistical; Neurons; Nonlinear Dynamics; Olivary Nucleus; Picrotoxin; Probability; Purkinje Cells; Rats; Rats, Sprague-Dawley; Synapses | 2020 |
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A | 2020 |
Astrocytes Control Sensory Acuity via Tonic Inhibition in the Thalamus.
Topics: Aldehyde Dehydrogenase 1 Family; Amine Oxidase (Copper-Containing); Animals; Astrocytes; Bestrophins; Female; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Inhibitory Postsynaptic Potentials; Macrolides; Male; Mice; Mice, Knockout; Microscopy, Electron; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Primary Cell Culture; Pyridazines; Retinal Dehydrogenase; RNA, Small Interfering; Thalamus; Touch Perception | 2020 |
Electrophysiological field potential identification of an intact GABAergic system in mouse cortical slices.
Topics: Action Potentials; Animals; Brain; Electrophysiological Phenomena; gamma-Aminobutyric Acid; Mice, Inbred C57BL; Neurons; Picrotoxin; Seizures | 2021 |
Agonist and antagonist properties of an insect GABA-gated chloride channel (RDL) are influenced by heterologous expression conditions.
Topics: 3' Untranslated Regions; Amino Acid Sequence; Animals; Bees; Chloride Channel Agonists; Chloride Channels; Drosophila melanogaster; Drosophila Proteins; Female; gamma-Aminobutyric Acid; Picrotoxin; Propofol; Receptors, Glycine; Sesterterpenes; Xenopus laevis | 2021 |
GABA
Topics: Acids; Animals; Bicuculline; Caffeine; Cyclohexenes; Disease Models, Animal; Electroencephalography; Flavonoids; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Humulus; Hypnotics and Sedatives; Mice; Picrotoxin; Propiophenones; Receptors, GABA-A; Sleep; Sleep Initiation and Maintenance Disorders; Terpenes | 2021 |
Positive allosteric γ-aminobutyric acid type A receptor modulation prevents lipotoxicity-induced injury in hepatocytes in vitro.
Topics: Apoptosis; Calcium; Caspase 3; gamma-Aminobutyric Acid; HEK293 Cells; Hepatocytes; Humans; NF-kappa B; Palmitates; Picrotoxin; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, GABA; Receptors, GABA-A | 2022 |
Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization.
Topics: Animals; Asthma; Calcium; Calcium Signaling; Flumazenil; gamma-Aminobutyric Acid; Inositol; Ligands; Lung; Methacholine Chloride; Mice; Muscle Contraction; Muscle, Smooth; Picrotoxin | 2022 |
The ethanol inhibition of basolateral amygdala neuron spiking is mediated by a γ-aminobutyric acid type A-mediated tonic current.
Topics: Animals; Basolateral Nuclear Complex; Central Amygdaloid Nucleus; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Picrotoxin; Receptors, GABA-A; Receptors, Glycine; Strychnine; Synaptic Transmission | 2022 |
Modulation of cholinergic, GABA-ergic and glutamatergic components of superior colliculus affect REM sleep in rats.
Topics: Animals; Cholinergic Agents; Dizocilpine Maleate; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Rats; Scopolamine; Sleep, REM; Superior Colliculi; Wakefulness | 2023 |
Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico.
Topics: Acetamides; Action Spectrum; Animals; Anticonvulsants; Caffeine; gamma-Aminobutyric Acid; Mice; Molecular Docking Simulation; Pentylenetetrazole; Picrotoxin; Seizures; Strychnine | 2022 |
Structure and dynamics of differential ligand binding in the human ρ-type GABA
Topics: Bicuculline; Binding Sites; gamma-Aminobutyric Acid; Humans; Ligands; Picrotoxin; Receptors, GABA-A | 2023 |