Page last updated: 2024-08-23

picrotoxin and etomidate

picrotoxin has been researched along with etomidate in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Brenner, O; Quast, U1
Burch, TP; Ramanjaneyulu, R; Thyagarajan, R; Ticku, MK1
Ashton, D1
Braestrup, C; Honoré, T; Nielsen, M1
Ramanjaneyulu, R; Ticku, MK1
Biggio, G; Casula, A; Murgia, A; Sanna, E1
Bonnert, TP; Cagetti, E; Thompson, SA; Wafford, KA; Whiting, PJ1
Jacobson, G; Melin, S; Sleigh, JW; Voss, LJ1
Eger, EI; Jurd, R; Laha, KT; Lor, C; Oh, I; Pearce, RA; Rau, V; Rodgers, FC; Rudolph, U; Zarnowska, ED1
Engin, E; Keist, R; Laha, KT; Pearce, RA; Rodgers, FC; Rudolph, U; Zarnowska, ED; Zeller, A1
Czajkowski, C; Ghosh, B; Tsao, TW1
Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y1

Other Studies

12 other study(ies) available for picrotoxin and etomidate

ArticleYear
Modulation of [3H]muscimol binding in rat cerebellar and cerebral cortical membranes by picrotoxin, pentobarbitone, and etomidate.
    Journal of neurochemistry, 1983, Volume: 41, Issue:2

    Topics: Animals; Cell Membrane; Cerebellar Cortex; Cerebral Cortex; Etomidate; Imidazoles; Kinetics; Male; Muscimol; Organ Specificity; Oxazoles; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1983
Barbiturate interactions with benzodiazepine-GABA receptor-ionophore complex.
    Advances in biochemical psychopharmacology, 1983, Volume: 37

    Topics: Animals; Barbiturates; Etomidate; In Vitro Techniques; Ionophores; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes

1983
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
    European journal of pharmacology, 1983, Oct-28, Volume: 94, Issue:3-4

    Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures

1983
Binding of 3H-DMCM to benzodiazepine receptors; chloride dependent allosteric regulation mechanisms.
    Journal of neural transmission, 1983, Volume: 58, Issue:1-2

    Topics: Animals; Anions; Carbolines; Cerebral Cortex; Chlorides; Etomidate; Indoles; Molecular Conformation; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes

1983
Binding characteristics and interactions of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site.
    Journal of neurochemistry, 1984, Volume: 42, Issue:1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Convulsants; Diazepam; Etomidate; gamma-Aminobutyric Acid; Male; Membranes; Pentobarbital; Picrotoxin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Sesterterpenes

1984
Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 1997, Volume: 51, Issue:3

    Topics: Anesthetics; Animals; Binding Sites; Chlorides; Etomidate; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis

1997
Overexpression of the GABA(A) receptor epsilon subunit results in insensitivity to anaesthetics.
    Neuropharmacology, 2002, Volume: 43, Issue:4

    Topics: Anesthetics; Anesthetics, Intravenous; Animals; Blotting, Western; Cell Line; Cloning, Molecular; DNA, Complementary; Etomidate; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Pentobarbital; Picrotoxin; Protein Engineering; Receptors, GABA-A; Steroids; Transfection; Xenopus laevis

2002
GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity.
    Brain research, 2010, Nov-11, Volume: 1360

    Topics: Animals; Connexins; Electroencephalography; Electrophysiological Phenomena; Etomidate; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junction delta-2 Protein; Gap Junctions; Hypnotics and Sedatives; In Vitro Techniques; Magnesium Deficiency; Male; Mefloquine; Mice; Mice, Inbred C57BL; Mice, Knockout; Picrotoxin; Receptors, GABA-A; Seizures

2010
Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABA(A) receptor.
    Neuropharmacology, 2015, Volume: 93

    Topics: Animals; Conditioning, Classical; Dose-Response Relationship, Drug; Etomidate; GABA Antagonists; HEK293 Cells; Hippocampus; Humans; Hypnotics and Sedatives; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Learning Disabilities; Long-Term Potentiation; Male; Mice; Mice, Transgenic; Neural Inhibition; Picrotoxin; Point Mutation; Pyramidal Cells; Receptors, GABA-A

2015
Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jul-01, Volume: 35, Issue:26

    Topics: Animals; Biophysics; Electric Stimulation; Etomidate; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Picrotoxin; Receptors, GABA-A

2015
A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
    Neuropharmacology, 2017, Volume: 125

    Topics: Animals; Bacterial Proteins; Cell Membrane; Chlorides; Etomidate; Extracellular Space; gamma-Aminobutyric Acid; Humans; Ligand-Gated Ion Channels; Membrane Potentials; Mutation; Neurotransmitter Agents; Oocytes; Pentobarbital; Picrotoxin; Propofol; Protein Domains; Protons; Receptors, GABA-B; Recombinant Fusion Proteins; Xenopus laevis

2017
Shared structural mechanisms of general anaesthetics and benzodiazepines.
    Nature, 2020, Volume: 585, Issue:7824

    Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A

2020