Page last updated: 2024-08-23

picrotoxin and dextrothyroxine

picrotoxin has been researched along with dextrothyroxine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199013 (41.94)18.7374
1990's10 (32.26)18.2507
2000's6 (19.35)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colquhoun, L; Holden-Dye, L; Walker, RJ1
Bowman, JW; Lee, BL; Thompson, DP; Whaley, HA1
Haber, CL; Heckaman, CL; Li, GP; Thompson, DP; Whaley, HA; Wiley, VH1
Fukuda, H; Matsumoto, K; Ono, H; Yamazaki, J1
Kirkness, EF; Turner, AJ1
Barton, R; Button, C; Honey, P; Rickford, P1
Albert, J; Lingle, CJ; Marder, E; O'Neil, MB1
Ansay, M; Plume, C; Sivine, F1
Inagaki, C; Ishiko, J; Takaori, S1
Drexler, G; Sieghart, W1
Calcott, PH; Fatig, RO1
Ishii, AI; Kino, H; Sano, M; Terada, M1
Kass, IS; Stretton, AO; Walrond, JP; Wang, CC1
DeHaven, R; Pong, SS; Wang, CC1
Birtle, AJ; Roberts, IT; Wright, DJ1
Bush, M; Teare, JA1
Crichlow, EC; Kim, JS1
Candura, SM; Coccini, T; Costa, LG; Manzo, L; Tonini, M1
Bormann, J; Schönrock, B1
Conder, GA; Johnson, SS; Thompson, DP1
Roder, JD; Stair, EL1
Arena, JP; Cully, DF; Etter, A; Liu, KK; Reiss, B; Schaeffer, JM; Vassilatis, DK1
Drinyaev, VA; Grichenko, AS; Kokoz, YM; Korystova, AF; Kruglyak, EB; Mosin, VA; Sterlina, TS; Tsyganova, VG; Victorov, AV; Zenchenko, KI1
Bernardi, MM; de Souza Spinosa, H; Gerenutti, M1
Horoszok, L; Raymond, V; Sattelle, DB; Wolstenholme, AJ1
Bernardi, MM; Spinosa, Hde S; Stilck, SR1
Holden-Dye, L; Walker, RJ1
Dibas, MI; Lester, HA; Lynch, JW; Pless, SA1
Bush, E; Foreman, R; Holden-Dye, L; Walker, RJ1
Brown, DD; Forrester, SG; Kaji, MD; Siddiqui, SZ1
Bertrand, D; Horlacher, R; Juneja, P; Krause, R; Marger, F; Welte, W1

Reviews

1 review(s) available for picrotoxin and dextrothyroxine

ArticleYear
An overview of ivermectin toxicosis.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:6

    Topics: Animals; Anthelmintics; Antidotes; Drug Overdose; Ivermectin; Physostigmine; Picrotoxin; Poisoning

1998

Other Studies

30 other study(ies) available for picrotoxin and dextrothyroxine

ArticleYear
Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum.
    Acta biologica Hungarica, 1992, Volume: 43, Issue:1-4

    Topics: Animals; Ascaris suum; Bicuculline; Cholinergic Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ivermectin; Muscles; Organophosphorus Compounds; Parasympatholytics; Parasympathomimetics; Picrotoxin; Receptors, Cholinergic; Receptors, GABA-A

1992
Effects of dihydroavermectin B1a and analogs on stretcher muscle of the lined shore crab, Pachygrapsus crassipes.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:3

    Topics: Animals; Anthelmintics; Bicuculline; Brachyura; Caenorhabditis; Chlorides; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Membrane Potentials; Membranes; Motor Endplate; Muscimol; Muscles; Picrotoxin; Sesterterpenes; Structure-Activity Relationship; Synapses; Time Factors

1991
Development of a mechanism of action-based screen for anthelmintic microbial metabolites with avermectinlike activity and isolation of milbemycin-producing Streptomyces strains.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:9

    Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Brachyura; Caenorhabditis; Cells, Cultured; Chlorides; Ion Channels; Ivermectin; Macrolides; Picrotoxin; Streptomyces

1991
Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1989, Volume: 93, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bicuculline; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Macrolides; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Sesterterpenes; Spinal Cord

1989
The stimulatory effects of secobarbital and pregnanolone on the GABAA receptor can be blocked selectively.
    European journal of pharmacology, 1988, Jun-10, Volume: 150, Issue:3

    Topics: Animals; Anthelmintics; Cerebral Cortex; In Vitro Techniques; Ivermectin; Muscimol; Phenobarbital; Picrotoxin; Pregnanes; Pregnanolone; Radioligand Assay; Receptors, GABA-A; Secobarbital; Sesterterpenes; Swine; Synaptic Membranes

1988
Avermectin toxicity in calves and an evaluation of picrotoxin as an antidote.
    Australian veterinary journal, 1988, Volume: 65, Issue:5

    Topics: Animals; Anthelmintics; Antidotes; Cattle; Cattle Diseases; Drug Evaluation; Female; Ivermectin; Male; Picrotoxin

1988
A GABA-activated chloride-conductance not blocked by picrotoxin on spiny lobster neuromuscular preparations.
    British journal of pharmacology, 1986, Volume: 87, Issue:4

    Topics: Action Potentials; Animals; Chlorides; Drug Resistance; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Muscimol; Nephropidae; Neuromuscular Junction; Picrotoxin; Species Specificity

1986
Picrotoxin, the antidote to ivermectin in dogs?
    The Veterinary record, 1985, Feb-16, Volume: 116, Issue:7

    Topics: Animals; Antidotes; Dog Diseases; Dogs; Insecticides; Ivermectin; Lactones; Male; Mite Infestations; Picrotoxin

1985
Effects of avermectin B1a and picrotoxin on striatal release of dopamine with reference to replacement of extracellular chloride with nitrate.
    Neuropharmacology, 1985, Volume: 24, Issue:12

    Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Chlorides; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Male; Nitrates; Picrotoxin; Rats; Rats, Inbred Strains; Tetrodotoxin; Verapamil

1985
Evidence for association of a high affinity avermectin binding site with the benzodiazepine receptor.
    European journal of pharmacology, 1984, Jun-01, Volume: 101, Issue:3-4

    Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cerebellar Cortex; Chlorides; Flunitrazepam; In Vitro Techniques; Ivermectin; Lactones; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Temperature

1984
Avermectin modulation of GABA binding to membranes of rat brain, brine shrimp and a fungus, Mucor miehei.
    The Journal of antibiotics, 1984, Volume: 37, Issue:7

    Topics: Animals; Bicuculline; Brain; Chlorides; Decapoda; gamma-Aminobutyric Acid; Ivermectin; Kinetics; Lactones; Male; Mucor; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sodium

1984
Angiostrongylus cantonensis: paralysis due to avermectin B1a and ivermectin.
    Experimental parasitology, 1984, Volume: 57, Issue:2

    Topics: Adrenergic alpha-Antagonists; Alkaloids; Angiostrongylus; Animals; Anthelmintics; Bicuculline; Ivermectin; Lactones; Metastrongyloidea; Movement; Muscle Contraction; Phenylephrine; Physostigmine; Picrotoxin; Pyrantel; Quinolizines; Strychnine

1984
Avermectin B1a, a paralyzing anthelmintic that affects interneurons and inhibitory motoneurons in Ascaris.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:10

    Topics: Animals; Anthelmintics; Ascaris; Behavior, Animal; Caenorhabditis; Interneurons; Ivermectin; Lactones; Metabolism; Motor Neurons; Neural Inhibition; Neuromuscular Junction; Picrotoxin; Synaptic Transmission

1980
A comparative study of avermectin B1a and other modulators of the gamma-aminobutyric acid receptor . chloride ion channel complex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1982, Volume: 2, Issue:7

    Topics: Animals; Anthelmintics; Benzodiazepines; Brain; Chlorides; Clonazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Male; Pentobarbital; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptic Membranes

1982
Triphasic locomotor response of a plant-parasitic nematode to avermectin: inhibition by the GABA antagonists bicuculline and picrotoxin.
    Parasitology, 1984, Volume: 88 ( Pt 2)

    Topics: Animals; Anthelmintics; Bicuculline; Ivermectin; Lactones; Motor Activity; Nematoda; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission

1984
Toxicity and efficacy of ivermectin in chelonians.
    Journal of the American Veterinary Medical Association, 1983, Dec-01, Volume: 183, Issue:11

    Topics: Animals; Animals, Zoo; Anthelmintics; Insecticides; Intestinal Diseases, Parasitic; Ivermectin; Lactones; Nematode Infections; Paresis; Picrotoxin; Turtles

1983
Clinical signs of ivermectin toxicity and the efficacy of antigabaergic convulsants as antidotes for ivermectin poisoning in epileptic chickens.
    Veterinary and human toxicology, 1995, Volume: 37, Issue:2

    Topics: Animals; Antidotes; Carbolines; Chickens; Epilepsy; GABA Antagonists; Ivermectin; Pentylenetetrazole; Picrotoxin; Poultry Diseases

1995
Interaction of the neurotoxic pesticides ivermectin and lindane with the enteric GABAA receptor-ionophore complex in the guinea-pig.
    European journal of pharmacology, 1993, Jun-01, Volume: 248, Issue:1

    Topics: Animals; Chloride Channels; Female; GABA-A Receptor Antagonists; Guinea Pigs; Hexachlorocyclohexane; In Vitro Techniques; Intestine, Small; Isometric Contraction; Ivermectin; Male; Membrane Proteins; Muscle, Smooth; Picrotoxin; Pyridazines; Receptors, GABA-A; Scopolamine; Sesterterpenes; Taurine; Tetrodotoxin

1993
Activation of Cl- channels by avermectin in rat cultured hippocampal neurons.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6

    Topics: Animals; Animals, Newborn; Anthelmintics; Cells, Cultured; Chloride Channels; Electrophysiology; Hippocampus; Ivermectin; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes

1993
Demonstration of co-resistance of Haemonchus contortus to ivermectin and moxidectin.
    The Veterinary record, 1993, Jun-26, Volume: 132, Issue:26

    Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Brachyura; Drug Resistance; Female; Gerbillinae; Haemonchiasis; Haemonchus; Ivermectin; Macrolides; Membrane Potentials; Muscle, Smooth; Picrotoxin

1993
Picrotoxin blockade of invertebrate glutamate-gated chloride channels: subunit dependence and evidence for binding within the pore.
    Journal of neurochemistry, 1999, Volume: 72, Issue:1

    Topics: Amino Acid Sequence; Animals; Antinematodal Agents; Binding Sites; Caenorhabditis elegans; Chloride Channels; Drug Interactions; Drug Resistance; Electrophysiology; GABA Antagonists; Glutamic Acid; Ion Channel Gating; Ivermectin; Kinetics; Membrane Potentials; Molecular Sequence Data; Oocytes; Picrotoxin; Point Mutation; Protein Structure, Tertiary; Xenopus

1999
Selective cytostatic and neurotoxic effects of avermectins and activation of the GABAalpha receptors.
    Bioscience reports, 1999, Volume: 19, Issue:6

    Topics: Animals; Bicuculline; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Ivermectin; Male; Neuroblastoma; Neurons; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Septal Nuclei; Tumor Cells, Cultured

1999
Anxiolytic and anticonvulsant properties of doramectin in rats: behavioral and neurochemistric evaluations.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2000, Volume: 127, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Brain Chemistry; Convulsants; Female; gamma-Aminobutyric Acid; Grooming; Ivermectin; Motor Activity; Neurotransmitter Agents; Picrotoxin; Rats; Rats, Wistar; Synaptic Transmission

2000
GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans.
    British journal of pharmacology, 2001, Volume: 132, Issue:6

    Topics: Amino Acid Sequence; Animals; Antinematodal Agents; Antiparasitic Agents; Bridged Bicyclo Compounds; Caenorhabditis elegans; Chloride Channels; Convulsants; DNA, Complementary; Insecticides; Ivermectin; Molecular Sequence Data; Nitriles; Oocytes; Picrotoxin; Polymerase Chain Reaction; Pyrazoles; Sequence Homology, Amino Acid; Sesterterpenes; Transfection; Xenopus laevis

2001
Possible anxiolytic effects of ivermectin in rats.
    Veterinary research communications, 2002, Volume: 26, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Behavior, Animal; Diazepam; Ivermectin; Locomotion; Male; Picrotoxin; Rats; Rats, Wistar; Seizures

2002
Actions of glutamate and ivermectin on the pharyngeal muscle of Ascaridia galli: a comparative study with Caenorhabditis elegans.
    International journal for parasitology, 2006, Volume: 36, Issue:4

    Topics: Action Potentials; Animals; Antinematodal Agents; Ascaridia; Caenorhabditis elegans; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ivermectin; Membrane Potentials; Pharyngeal Muscles; Picrotoxin; Species Specificity

2006
Conformational variability of the glycine receptor M2 domain in response to activation by different agonists.
    The Journal of biological chemistry, 2007, Dec-07, Volume: 282, Issue:49

    Topics: Animals; beta-Alanine; Female; Humans; Ivermectin; Oocytes; Picrotoxin; Protein Structure, Tertiary; Receptors, Glycine; Rhodamines; Spectrometry, Fluorescence; Structure-Activity Relationship; Strychnine; Taurine; Xenopus laevis

2007
The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes.
    Invertebrate neuroscience : IN, 2009, Volume: 9, Issue:3-4

    Topics: Animals; Anthelmintics; Barbiturates; Benzodiazepines; Caenorhabditis elegans; Chloride Channels; Female; Glutamic Acid; Ivermectin; Nitrobenzoates; Oocytes; Patch-Clamp Techniques; Picrotoxin; Stilbenes; Xenopus

2009
Pharmacological characterization of the Haemonchus contortus GABA-gated chloride channel, Hco-UNC-49: modulation by macrocyclic lactone anthelmintics and a receptor for piperazine.
    Veterinary parasitology, 2012, Apr-30, Volume: 185, Issue:2-4

    Topics: Animals; Anthelmintics; Chloride Channels; gamma-Aminobutyric Acid; Gene Expression Regulation; Haemonchus; Helminth Proteins; Insecticides; Ion Channel Gating; Ivermectin; Lactams, Macrocyclic; Macrolides; Oocytes; Picrotoxin; Piperazine; Piperazines; Pyrazoles; Receptors, Cell Surface; Xenopus laevis

2012
An internally modulated, thermostable, pH-sensitive Cys loop receptor from the hydrothermal vent worm Alvinella pompejana.
    The Journal of biological chemistry, 2014, May-23, Volume: 289, Issue:21

    Topics: Amino Acid Sequence; Animals; Antiparasitic Agents; Base Sequence; Cysteine Loop Ligand-Gated Ion Channel Receptors; Female; Hydrogen-Ion Concentration; Hydrothermal Vents; Ivermectin; Membrane Potentials; Molecular Sequence Data; Mutant Proteins; Mutation; Oocytes; Phylogeny; Picrotoxin; Polychaeta; Protein Stability; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Sf9 Cells; Temperature; Xenopus

2014