picrotoxin has been researched along with chlorine in 206 studies
*Chlorine: An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. [MeSH]
*Chlorine: An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 108 (52.43) | 18.7374 |
| 1990's | 65 (31.55) | 18.2507 |
| 2000's | 26 (12.62) | 29.6817 |
| 2010's | 7 (3.40) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Badole, SL; Bhardwaj, S; Bodhankar, SL; Patel, NM | 1 |
| Narikawa, Y; Sugi, H; Suzuki, S | 1 |
| Miller, T; Olsen, RW; Ticku, MK | 1 |
| Ban, M; Olsen, RW; Ticku, MK | 1 |
| Marder, E; Paupardin-Tritsch, D | 1 |
| Homma, S | 1 |
| Karobath, M; Supavilai, P | 1 |
| Plourde, G; Tremblay, JP | 1 |
| Benjamin, AM; Okamoto, K; Quastel, JH | 1 |
| Gallagher, JP; Higashi, H; Nishi, S | 1 |
| Carpenter, DO; Yarowsky, J | 1 |
| Homma, S; Rovainen, CM | 1 |
| Olsen, RW; Ticku, MK | 1 |
| Okamoto, K; Quastel, DM; Quastel, JH | 1 |
| Furuya, N; Kawano, K; Shimazu, H | 1 |
| Delaleu, JC | 1 |
| Constanti, A; Nistri, A | 2 |
| Cull-Candy, SG | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 1 |
| Hara, N; Ichinose, M; Sawada, M | 1 |
| Angelotti, TP; MacDonald, RL; Porter, NM; Twyman, RE | 1 |
| Freschi, JE; Kerrison, J | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 1 |
| Ticku, MK | 2 |
| Cupello, A; Hydén, H; Palm, A; Rapallino, MV | 1 |
| Lindgren, S; Meyerson, B; Westerling, P | 1 |
| Bitran, D; Kellogg, CK; Primus, RJ | 1 |
| Bowman, JW; Lee, BL; Thompson, DP; Whaley, HA | 1 |
| Bloomquist, JR; Grubs, RE; Knipple, DC; Soderlund, DM | 1 |
| Kaneko, A; Suzuki, S; Tachibana, M | 1 |
| Allen, TG; Burnstock, G | 1 |
| Gettins, D; Goldsack, N; Ibegbuna, V; Stanford, SC | 1 |
| Kaila, K; Pasternack, M; Rydqvist, B; Voipio, J | 1 |
| Akagi, H; Hirai, K; Hishinuma, F | 1 |
| Haber, CL; Heckaman, CL; Li, GP; Thompson, DP; Whaley, HA; Wiley, VH | 1 |
| Arata, A; Homma, I; Onimaru, H | 1 |
| Fincher, AS; Frye, GD; Griffith, WH; Lorenzetti, M; Trzeciakowski, J | 1 |
| Basille, C; Cazin, L; Jenks, BG; Louiset, E; Tonon, MC; van de Put, FH; Vaudry, H | 1 |
| Kontro, P; Korpi, ER; Oja, SS | 1 |
| Cupello, A; Hydén, H; Rapallino, MV | 2 |
| Gee, KW; Lawrence, LJ; Yamamura, HI | 1 |
| Akaike, N; Ishizuka, S; Yasui, S | 1 |
| Paul, SM; Schwartz, RD; Skolnick, P; Suzdak, PD | 1 |
| Allan, AM; Harris, RA | 2 |
| Aihara, H; Kurachi, M | 1 |
| Armstrong, WE; Sladek, CD | 1 |
| Nichols, AC; Snead, OC | 1 |
| David, JA; Pinnock, RD; Sattelle, DB; Wafford, KA | 1 |
| Fishman, BE; Gianutsos, G | 1 |
| Akaike, N; Inoue, M | 1 |
| Lux, HD; Misgeld, U; Müller, W | 1 |
| Fukuda, H; Matsumoto, K; Ono, H; Yamazaki, J | 1 |
| Mienville, JM; Vicini, S | 1 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Franke, C; Hatt, H; Zufall, F | 1 |
| Kaila, K; Pasternack, M; Saarikoski, J; Voipio, J | 1 |
| Becker, CM; Betz, H; Grenningloh, G; Kettenmann, H; Pritchett, DB; Schofield, PR; Seeburg, PH; Sontheimer, H | 1 |
| Baur, R; Peter, AB; Sigel, E; Yao, Y | 1 |
| Paul, SM; Schwartz, RD; Seale, TW; Skolnick, P | 1 |
| Miller, LG; Roy, RB; Weill, CL | 1 |
| Cottrell, GA; Lambert, JJ; Peters, JA | 1 |
| Chang, YF; Gao, XM | 1 |
| Akaike, N; Carpenter, DO; Hattori, K; Oomura, Y | 1 |
| Cooper, SJ; Estall, LB | 1 |
| Cardinali, DP; Rosenstein, RE; Sanjurjo, C | 1 |
| File, SE | 1 |
| Cupello, A; Hydén, H; Palm, A | 2 |
| Crofton, KM; Reiter, LW | 1 |
| Barnard, EA; Blair, LA; Dionne, VE; Levitan, ES; Marshall, J | 1 |
| Boakes, RJ; Hardy, JA; Turner, JD; Virmani, MA | 1 |
| Dichter, MA; Snodgrass, SR; White, WF | 1 |
| Martin, JV; Mendelson, WB; Roseberry, C; Skolnick, P; Squires, R; Wagner, R; Weissman, BA | 1 |
| Kempner, ES; Paul, SM; Schwartz, RD; Skolnick, P; Thomas, JW | 1 |
| Abramets, II; Komissarov, IV | 1 |
| Jackson, JA; Paul, SM; Schwartz, RD; Skolnick, P; Weigert, D | 1 |
| Bloomquist, JR; Soderlund, DM | 1 |
| Abalis, I; Eldefrawi, AT; Eldefrawi, ME; Sattelle, DB; Wafford, KA | 1 |
| Majewska, MD; Schwartz, RD | 1 |
| Eldefrawi, AT; Eldefrawi, ME; Gant, DB | 1 |
| Akaike, N; Inomata, N; Oyama, Y; Tokutomi, N | 1 |
| Thomson, AM | 1 |
| Blaxter, TJ; Carlen, PL | 1 |
| Akaike, N; Maruyama, T; Tokutomi, N | 1 |
| Covey, DF; Ferrendelli, JA; Levine, JA; Naritoku, DK | 1 |
| Cupello, A; Hydén, H | 1 |
| Albert, J; Lingle, CJ; Marder, E; O'Neil, MB | 1 |
| Kaneko, A; Tachibana, M | 1 |
| Blaxter, TJ; Cottrell, GA | 1 |
| Inagaki, C; Ishiko, J; Takaori, S | 1 |
| Florey, E; Murdock, LL | 1 |
| Florey, E; Iwasaki, S | 1 |
| Curtis, DR | 1 |
| Barker, JL; Nicoll, RA | 1 |
| Bornstein, MB; Crain, SM | 1 |
| Karczmar, AG; Minota, S; Nishi, S | 1 |
| Elliott, KA; Gottesfeld, Z | 1 |
| Ito, Y; Kuriyama, H; Tashiro, N | 1 |
| Takeuchi, A; Takeuchi, N | 1 |
| Kerkut, GA; Pitman, RM | 1 |
| Drexler, G; Sieghart, W | 1 |
| Calcott, PH; Fatig, RO | 1 |
| Abe, T; Hori, S; Kawai, N; Niwa, A | 1 |
| Constanti, A; Smart, TG | 1 |
| Maksay, G; Ticku, MK | 1 |
| Barker, JL; Segal, M | 1 |
| Ghiasuddin, SM; Matsumura, F | 1 |
| Kato, E; Kuba, K | 1 |
| Leeb-Lundberg, F; Olsen, RW | 1 |
| Fujimoto, M; Okabayashi, T | 1 |
| Olsen, RW | 1 |
| Kerr, DI; Krantis, A | 1 |
| DeHaven, R; Pong, SS; Wang, CC | 1 |
| Covey, DF; Ferrendelli, JA; Kalman, BL; Klunk, WE | 1 |
| Olsen, RW; Stephenson, FA | 1 |
| Braestrup, C; Honoré, T; Nielsen, M | 1 |
| Hollingsworth, EB; Paul, SM; Schwartz, RD; Skolnick, P | 1 |
| Burke, TR; Rice, KC; Skolnick, P; Weissman, BA | 1 |
| Hablitz, JJ | 1 |
| Desarmenien, M; Feltz, P; Headley, PM; Santangelo, F | 1 |
| Ayala, GF; Peck, EJ; Thalmann, RH | 1 |
| Lingle, C; Marder, E | 1 |
| Ogata, K; Takata, M | 1 |
| Dowling, JE; Grant, GB | 1 |
| Carter, DB; Dillon, GH; Im, WB; McKinley, DD | 1 |
| Akaike, N; Nielsen, M; Rutherford, D; Tokutomi, N | 1 |
| Angelides, KJ; Duffy, S; Fraser, DD; Kettenmann, H; MacVicar, BA; Perez-Velazquez, JL | 1 |
| Lukasiewicz, PD; Werblin, FS | 1 |
| Mody, I; Soltesz, I | 1 |
| Brinton, RD | 1 |
| Samochocki, M; Strosznajder, J | 1 |
| Belykh, NP; Glebov, RN; Kryzhanovskiĭ, GN; Rebrov, IG; Shukalova, TF | 1 |
| Aréchiga, H; García, U; Onetti, C; Valdiosera, R | 1 |
| Blackmore, PF; Bleasdale, JE; Im, WB | 1 |
| Barker, JL; Schaffner, AE; Vautrin, J | 1 |
| Pomés, A; Rodríguez-Farré, E; Suñol, C | 1 |
| Lukasiewicz, PD; Maple, BR; Werblin, FS | 1 |
| Cammack, JN; Schwartz, EA | 1 |
| Covey, DF; Rothman, SM; Yoon, KW | 1 |
| Ashe, JH; Metherate, R | 1 |
| Dunn, SM; Thuynsma, RP | 1 |
| Jackson, MB; Zhang, SJ | 1 |
| Peris, J | 1 |
| Elson, RC; Selverston, AI | 1 |
| Miller, RF; Yu, W | 1 |
| Fukura, H; Igarashi, M; Komiya, Y | 1 |
| Amato, F; Biggio, G; Deserra, T; Motzo, C; Murgia, A; Sanna, E | 1 |
| Donevan, SD; Rho, JM; Rogawski, MA | 1 |
| Biggio, G; Casula, A; Murgia, A; Sanna, E | 1 |
| Miyata, H; Nagayama, T; Takahata, M | 1 |
| Kettenmann, H; Labrakakis, C; Müller, T; Schmidt, K | 1 |
| Sousa, A; Ticku, MK | 1 |
| Aguayo, LG; Tapia, JC | 1 |
| Chang, Y; Weiss, DS | 1 |
| Bévengut, M; Cattaert, D; Pearlstein, E; Watson, AH | 1 |
| Fuse, T; Wotring, VE; Yoon, KW | 1 |
| Bate, JR; Platt, B; von Linstow Roloff, E; Withington, DJ | 1 |
| Cutting, GR; Enz, R | 1 |
| de Jeu, MT; Dudek, FE; Gribkoff, VK; Park, WK; Pennartz, CM; Pieschl, RL; Strecker, GJ; Wisialowski, TA | 1 |
| Lees, G; Nicholson, RA; Verdon, B; Zheng, J | 1 |
| Perkins, KL | 1 |
| Chen, CL; Chiu, TH; Yang, YR | 1 |
| Chen, Q; Hardy, K; Moulder, K; Olney, JW; Romano, C; Tenkova, T | 1 |
| Clarac, F; Fellippa-Marques, S; Vinay, L | 1 |
| Bence, M; Everest, H; Forrest-Owen, W; Lightman, SL; McArdle, CA; Williams, B | 1 |
| Connaughton, VP; Nelson, R | 1 |
| Ye, J | 1 |
| Gunthorpe, MJ; Mellor, JR; Randall, AD | 1 |
| Athas, GB; Guth, PS; Holt, JC; Pantoja, AM | 1 |
| Delpire, E; Kirby, M; Lovinger, DM; McDonald, MP; Sung, KW | 1 |
| Flores-Herr, N; Protti, DA; Wässle, H | 1 |
| Baufreton, J; Bioulac, B; Dovero, S; Dufy, B; Garret, M; Taupignon, A | 1 |
| Gao, F; Pang, JJ; Wu, SM | 1 |
| Chattipakorn, SC; McMahon, LL | 1 |
| Menzikov, S; Menzikova, O | 1 |
| Lee, D; O'Dowd, DK; Su, H | 1 |
| GRUNDFEST, H; USHERWOOD, PN | 1 |
| MAGISTRETTI, MJ; SETNIKAR, I | 1 |
| Beg, AA; Jorgensen, EM | 1 |
| Bai, D; Buckingham, SD; Chen, HH; Rauh, JJ; Sattelle, DB; Skeer, JM | 1 |
| Hull, C; von Gersdorff, H | 1 |
| Cao, J; Cui, M; Li, H; Sun, X; Xu, L; Xu, T; Yang, J; Zeng, B; Zhang, J; Zhang, Z | 1 |
| Menzikov, SA; Menzikova, OV | 1 |
| Holden-Dye, L; Walker, RJ | 1 |
| Augustine, GJ; Berglund, K; Feng, G; Kuner, T; Pond, BB; Schwartz-Bloom, RD | 1 |
| Inoue, H; Okada, Y | 1 |
| Hwang, JC; Lee, MC; Lin, JT; Tung, LC | 1 |
| Ernest, NJ; Habela, CW; Sontheimer, H; Swindall, AF | 1 |
| Héja, L; Kardos, J; Lasztóczi, B; Nyitrai, G | 1 |
| Stepanov, II; Yakimovskii, AF | 1 |
| Bach, EC; Smith, BN | 1 |
| Distler, C; Hoffmann, KP; Spoida, K; Trampe, AK | 1 |
| Li, P; Slaughter, MM | 1 |
| Islam, R; Lynch, JW; Sah, P; Xu, L; Zhang, Y | 1 |
| Czajkowski, C; Ghosh, B; Tsao, TW | 1 |
| Ito, K; Kawamura, Y; Takata, M | 1 |
| Isenberg, KE; Yang, J; Zorumski, CF | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Nabeshima, A; Saito, T; Takahata, N; Toki, S | 1 |
| Ho, IK; Ito, Y | 1 |
| Campusano, JM; Jiang, SA; O'Dowd, DK; Su, H | 1 |
| Endeman, D; Fahrenfort, I; Kamermans, M; Sjoerdsma, T; Steijaert, M; Ten Eikelder, H | 1 |
8 review(s) available for picrotoxin and chlorine
| Article | Year |
|---|---|
Interactions of pyrethroid insecticides with chloride ionophore-associated binding sites.
Topics: Animals; Benzodiazepinones; Brain; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Drug Interactions; Guinea Pigs; Ion Channels; Picrotoxin; Pyrethrins; Radioligand Assay; Rats; Receptors, GABA-A; Sesterterpenes | 1985 |
Behavioural pharmacology of food, water and salt intake in relation to drug actions at benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Appetite; Appetite Depressants; Benzodiazepines; Benzodiazepinones; Carbolines; Chlordiazepoxide; Chlorides; Choice Behavior; Diazepam; Drinking Behavior; Feeding Behavior; Flumazenil; Food Deprivation; Food Preferences; gamma-Aminobutyric Acid; Ion Channels; Midazolam; Picrotoxin; Punishment; Pyrazoles; Receptors, GABA-A; Satiation; Sodium Chloride; Species Specificity | 1985 |
The contribution of behavioural studies to the neuropharmacology of anxiety.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Binding Sites; Carbolines; Chlorides; Neuropharmacology; Norepinephrine; Picrotoxin; Pyrazoles; Receptors, GABA-A; Serotonin | 1987 |
The pharmacology of spinal postsynaptic inhibition.
Topics: Aminobutyrates; Animals; Cell Membrane Permeability; Chlorides; Electrophoresis; Glycine; Interneurons; Membrane Potentials; Motor Neurons; Picrotoxin; Potassium; Sodium; Spinal Cord; Strychnine; Synaptic Transmission; Tetanus Toxin | 1969 |
Convulsant/depressant site of action at the allosteric benzodiazepine-GABA receptor-ionophore complex.
Topics: Allosteric Regulation; Allosteric Site; Animals; Anti-Anxiety Agents; Barbiturates; Central Nervous System Depressants; Chlorides; Convulsants; Ion Channels; Picrotoxin; Protein Conformation; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1983 |
Convulsant and anticonvulsant drug binding sites related to GABA-regulated chloride ion channels.
Topics: Animals; Anticonvulsants; Barbiturates; Binding Sites; Brain Chemistry; Chlorides; Convulsants; gamma-Aminobutyric Acid; Humans; Ion Channels; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
The GABA postsynaptic membrane receptor-ionophore complex. Site of action of convulsant and anticonvulsant drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Bicuculline; Brain; Chlorides; Convulsants; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Seizures; Synaptic Membranes | 1981 |
Biochemical pharmacology of the GABA receptor-ionophore protein complex.
Topics: Animals; Brain; Chlorides; Flunitrazepam; Humans; Ion Channels; Ionophores; Kinetics; Muscimol; Nerve Tissue Proteins; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Sesterterpenes | 1983 |
198 other study(ies) available for picrotoxin and chlorine
| Article | Year |
|---|---|
Acute and chronic diuretic effect of ethanolic extract of leaves of Cocculus hirsutus (L.) Diles in normal rats.
Topics: Administration, Oral; Animals; Chlorides; Cocculus; Diuretics; Dose-Response Relationship, Drug; Drug Administration Schedule; Furosemide; Male; Plant Extracts; Plant Leaves; Potassium; Rats; Rats, Wistar; Sodium; Toxicity Tests, Acute | 2009 |
The effect of ions and drugs on the initiation and conduction of peristaltic wave in the heart of Ciona intestinalis.
Topics: Animals; Calcium; Chlorides; Choline; Cnidaria; Heart; Heart Rate; Manganese; Myocardial Contraction; Picrotoxin; Procaine; Sodium; Sulfates; Tetrodotoxin | 1976 |
Dihydropicrotoxinin binding to crayfish muscle sites possibly related to gamma-aminobutyric acid receptor-ionophores.
Topics: Aminobutyrates; Animals; Astacoidea; Cell Membrane; Chlorides; Cockroaches; GABA Antagonists; gamma-Aminobutyric Acid; Houseflies; In Vitro Techniques; Muscles; Picrotoxin; Receptors, Neurotransmitter; Subcellular Fractions; Synaptic Transmission | 1978 |
Binding of [3H]alpha-dihydropicrotoxinin, a gamma-aminobutyric acid synaptic antagonist, to rat brain membranes.
Topics: Aminobutyrates; Animals; Brain; Chlorides; GABA Antagonists; In Vitro Techniques; Male; Membranes; Organ Specificity; Picrotoxin; Rats; Receptors, Neurotransmitter; Subcellular Fractions | 1978 |
The pharmacological properties of some crustacean neuronal acetylcholine, gamma-aminobutyric acid, and L-glutamate responses.
Topics: Acetylcholine; Animals; Brachyura; Chlorides; gamma-Aminobutyric Acid; Ganglia; Glutamates; In Vitro Techniques; Male; Membrane Potentials; Neurons; Picrotoxin; Potassium; Receptors, Cholinergic; Synaptic Transmission | 1978 |
Conductance changes during bath application of beta-alanine and taurine in giant interneurons of the isolated lamprey spinal cord.
Topics: Alanine; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Electrolytes; gamma-Aminobutyric Acid; Glycine; Interneurons; Lampreys; Membrane Potentials; Picrotoxin; Spinal Cord; Strychnine; Taurine | 1979 |
Stimulation of benzodiazepine receptor binding by SQ 20009 is chloride-dependent and picrotoxin-sensitive.
Topics: Animals; Benzodiazepines; Brain; Chlorides; Etazolate; Flunitrazepam; In Vitro Techniques; Membranes; Nicotinic Acids; Picrotoxin; Rats; Receptors, Drug; Sodium Chloride; Stimulation, Chemical | 1979 |
Presynaptic modulating effects of GABA on depression, facilitation, and posttetanic potentiation of a cholinergic synapse in Aplysia californica.
Topics: Acetylcholine; Aminobutyrates; Animals; Aplysia; Azides; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Lithium; Membrane Potentials; Picrotoxin; Potassium; Sodium; Synapses | 1977 |
Effects of ammonium ions on spontaneous action potentials and on contents of sodium, potassium, ammonium and chloride ions in brain in vitro.
Topics: Action Potentials; Ammonium Chloride; Animals; Brain; Cell Membrane Permeability; Chlorides; Depression, Chemical; Diffusion; Glycolysis; Guinea Pigs; In Vitro Techniques; Microelectrodes; Neuroglia; Neurons; Picrotoxin; Potassium; Rats; Sodium; Strychnine | 1978 |
Characterization and ionic basis of GABA-induced depolarizations recorded in vitro from cat primary afferent neurones.
Topics: Aminobutyrates; Animals; Anions; Bicuculline; Cats; Cell Membrane Permeability; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons, Afferent; Picrotoxin; Receptors, Drug | 1978 |
A comparison of similar ionic responses to gamma-aminobutyric acid and acetylcholine.
Topics: Acetylcholine; Aminobutyrates; Animals; Aplysia; Bicuculline; Bungarotoxins; Cell Membrane Permeability; Chlorides; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Neurons; Picrotoxin; Potassium; Receptors, Drug; Sodium; Strychnine; Time Factors | 1978 |
Conductance increases produced by glycine and gamma-aminobutyric acid in lamprey interneurones.
Topics: Action Potentials; Aminobutyrates; Animals; Bicuculline; Chlorides; Electric Conductivity; Fishes; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Interneurons; Lampreys; Picrotoxin; Spinal Cord; Strychnine | 1978 |
gamma-Aminobutyric acid-stimulated chloride permeability in crayfish muscle.
Topics: Aminobutyrates; Animals; Astacoidea; Biological Transport; Chlorides; gamma-Aminobutyric Acid; Kinetics; Muscles; Permeability; Picrotoxin; Structure-Activity Relationship | 1977 |
Action of amino acids and convulsants on cerebellar spontaneous action potentials in vitro: effects of deprivation of C1-, K+ of Na+.
Topics: Action Potentials; Alanine; Amino Acids; Animals; Bicuculline; Cerebellum; Chlorides; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; Iodides; Isethionic Acid; Nitrates; Picrotoxin; Potassium; Sodium; Strychnine; Sulfates | 1976 |
Transcerebellar inhibitory interaction between the bilateral vestibular nuclei and its modulation by cerebellocortical activity.
Topics: Brain Stem; Cerebellar Cortex; Cerebellar Nuclei; Chlorides; Ear, Inner; Evoked Potentials; Membrane Potentials; Neural Inhibition; Neural Pathways; Picrotoxin; Reaction Time; Vestibular Nuclei | 1976 |
Evidence for a synaptically mediated decrease in conductance in a crustacean myocardium.
Topics: Animals; Biological Transport, Active; Chlorides; Cold Temperature; Crustacea; Electric Conductivity; Electric Stimulation; Heart; Membrane Potentials; Myocardial Contraction; Ouabain; Picrotoxin; Potassium; Sodium; Tetraethylammonium Compounds | 1976 |
The action of taurine on the lobster muscle fibre an d the frog spinal cord.
Topics: Animals; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Nephropidae; Neural Conduction; Picrotoxin; Receptors, Drug; Spinal Cord; Taurine; Tetrodotoxin | 1976 |
A comparative study of the action of gamma-aminobutyric acid and piperazine on the lobster muscle fibre and the frog spinal cord.
Topics: Aminobutyrates; Animals; Chlorides; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Nephropidae; Picrotoxin; Piperazines; Rana temporaria; Spinal Cord; Tetrodotoxin | 1976 |
Two types of extrajunctional L-glutamate receptors in locust muscle fibres.
Topics: Animals; Chlorides; Glutamates; Grasshoppers; Membrane Potentials; Muscles; Neuromuscular Junction; Picrotoxin; Receptors, Drug | 1976 |
Analysis of amino acid responses on frog motoneurones.
Topics: Alanine; Amino Acids; Animals; Chlorides; gamma-Aminobutyric Acid; Glutamates; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; Picrotoxin; Sodium; Strychnine; Taurine | 1976 |
Interleukin-2 inhibits the GABA-induced Cl- current in identified Aplysia neurons.
Topics: Animals; Aplysia; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Interleukin-2; Ion Channels; Membranes; Muscimol; Neurons; Picrotoxin; Recombinant Proteins; Seawater | 1992 |
Kinetic properties of alpha 1 beta 1 gamma-aminobutyric acidA receptor channels expressed in Chinese hamster ovary cells: regulation by pentobarbital and picrotoxin.
Topics: Animals; Chloride Channels; Chlorides; CHO Cells; Cricetinae; Ion Channel Gating; Kinetics; Membrane Potentials; Membrane Proteins; Models, Biological; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins | 1992 |
The effects of gamma-aminobutyric acid on voltage-clamped motoneurons of the lobster cardiac ganglion.
Topics: Animals; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Ganglia; Membrane Potentials; Motor Neurons; Nephropidae; Nipecotic Acids; Picrotoxin; Proline; Receptors, GABA-A; Sodium | 1992 |
Characterization of bicuculline/baclofen-insensitive gamma-aminobutyric acid receptors expressed in Xenopus oocytes. I. Effects of Cl- channel inhibitors.
Topics: Animals; Baclofen; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chloride Channels; Chlorides; Cloning, Molecular; Ion Channels; Membrane Proteins; Ovum; Picrotoxin; Rats; Receptors, GABA-A; Retina; RNA; Xenopus | 1992 |
Ethanol interactions at the gamma-aminobutyric acid receptor complex.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Chlorides; Dizocilpine Maleate; Embryo, Mammalian; Ethanol; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1991 |
Can Cl- ions be extruded from a gamma-aminobutyric (GABA)-acceptive nerve cell via GABAA receptors on the plasma membrane cytoplasmic side?
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; Cytoplasm; gamma-Aminobutyric Acid; Membrane Potentials; Models, Biological; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A; Vestibular Nucleus, Lateral | 1991 |
Functional changes in GABAA receptor stimulation during the oestrous cycle of the rat.
Topics: Animals; Chlorides; Estrogens; Estrus; Female; Flurazepam; In Vitro Techniques; Neurons, Afferent; Ovariectomy; Pentobarbital; Picrotoxin; Potassium; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Gestational exposure to diazepam increases sensitivity to convulsants that act at the GABA/benzodiazepine receptor complex.
Topics: Animals; Bicuculline; Caffeine; Carbolines; Cerebral Cortex; Chlorides; Convulsants; Diazepam; Female; GABA-A Receptor Antagonists; Male; Picrotoxin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, GABA-A; Seizures; Strychnine; Synaptosomes | 1991 |
Effects of dihydroavermectin B1a and analogs on stretcher muscle of the lined shore crab, Pachygrapsus crassipes.
Topics: Animals; Anthelmintics; Bicuculline; Brachyura; Caenorhabditis; Chlorides; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Membrane Potentials; Membranes; Motor Endplate; Muscimol; Muscles; Picrotoxin; Sesterterpenes; Structure-Activity Relationship; Synapses; Time Factors | 1991 |
Prolonged exposure to GABA activates GABA-gated chloride channels in the presence of channel-blocking convulsants.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Convulsants; Endrin; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sesterterpenes; Xenopus | 1991 |
Effects of glycine and GABA on isolated bipolar cells of the mouse retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Mice; Neurons; Pentobarbital; Picrotoxin; Potassium; Retina; Sodium; Strychnine | 1990 |
GABAA receptor-mediated increase in membrane chloride conductance in rat paratracheal neurones.
Topics: Animals; Bicuculline; Cell Membrane; Chlorides; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin; Trachea | 1990 |
Effects of GABAA receptor ligands on noradrenaline concentration and beta-adrenoceptor binding in mouse cerebral cortex.
Topics: Alkaloids; Animals; Azepines; Cerebral Cortex; Chlorides; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Bridged-Ring; Ion Channels; Kinetics; Lactones; Male; Mice; Neuromuscular Depolarizing Agents; Norepinephrine; Pentylenetetrazole; Picrotoxin; Piperidines; Receptors, Adrenergic, beta; Receptors, GABA-A; Yohimbine | 1990 |
Effect of gamma-aminobutyric acid on intracellular pH in the crayfish stretch-receptor neurone.
Topics: Acetazolamide; Action Potentials; Animals; Astacoidea; Bicarbonates; Chlorides; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Ion Channels; Mechanoreceptors; Membrane Potentials; Microelectrodes; Picrotoxin; Synaptic Membranes | 1991 |
Functional properties of strychnine-sensitive glycine receptors expressed in Xenopus oocytes injected with a single mRNA.
Topics: Acetylcholine; Amino Acid Sequence; Amino Acids; Animals; Base Sequence; Chlorides; Cloning, Molecular; DNA; Glycine; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Open Reading Frames; Picrotoxin; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Strychnine; Xenopus laevis | 1991 |
Development of a mechanism of action-based screen for anthelmintic microbial metabolites with avermectinlike activity and isolation of milbemycin-producing Streptomyces strains.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Brachyura; Caenorhabditis; Cells, Cultured; Chlorides; Ion Channels; Ivermectin; Macrolides; Picrotoxin; Streptomyces | 1991 |
Inhibitory synaptic inputs to the respiratory rhythm generator in the medulla isolated from newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Respiration; Strychnine; Synapses | 1990 |
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Taurine; Tetrodotoxin | 1990 |
Electrophysiological evidence for the existence of GABAA receptors in cultured frog melanotrophs.
Topics: alpha-MSH; Animals; Cells, Cultured; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; Male; Membrane Potentials; Membrane Proteins; Picrotoxin; Pituitary Gland, Posterior; Rana ridibunda; Ranidae; Receptors, GABA-A | 1990 |
Taurine interacts with GABAA and GABAB receptors in the brain.
Topics: Animals; Baclofen; Bicuculline; Brain; Chlorides; Female; GABA Antagonists; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Picrotoxin; Potassium; Receptors, GABA-A; Strychnine; Taurine | 1990 |
Stimulation of 36Cl- influx into rabbit cerebral cortex microsacs by the endogenous antigen S-100.
Topics: Animals; Bicuculline; Cerebral Cortex; Chlorides; Chlorine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Picrotoxin; Rabbits; Radioisotopes; S100 Proteins | 1990 |
GABA activates different types of chloride-conducting receptor-ionophore complexes in a dose-dependent manner.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Ion Channels; Picrotoxin; Rana catesbeiana; Receptors, GABA-A | 1985 |
Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.
Topics: Animals; Bicuculline; Biological Transport; Brain; Cell-Free System; Chlorides; Ethanol; In Vitro Techniques; Ion Channels; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Synaptosomes | 1986 |
Anesthetic and convulsant barbiturates alter gamma-aminobutyric acid-stimulated chloride flux across brain membranes.
Topics: Animals; Barbiturates; Brain; Chlorides; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred DBA; Pentobarbital; Picrotoxin; Receptors, GABA-A; Stereoisomerism | 1986 |
The action of taurine on the response to glutamate in the motoneuron of the isolated frog spinal cord.
Topics: Animals; Bicuculline; Chlorides; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Lithium; Motor Neurons; Ouabain; Picrotoxin; Potassium; Rana catesbeiana; Sodium; Spinal Cord; Strychnine; Taurine | 1985 |
gamma-Aminobutyric acid antagonists stimulate vasopressin release from organ-cultured hypothalamo-neurohypophyseal explants.
Topics: Acetylcholine; Animals; Bacitracin; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Ion Channels; Male; Nipecotic Acids; Organ Culture Techniques; Osmolar Concentration; Penicillins; Picrotoxin; Pituitary Gland, Posterior; Proline; Rats; Rats, Inbred Strains; Vasopressins | 1987 |
gamma-Hydroxybutyric acid binding sites: evidence for coupling to a chloride anion channel.
Topics: Adult; Aged; Animals; Chlorides; Hippocampus; Humans; Hydroxybutyrates; In Vitro Techniques; Ion Channels; Male; Middle Aged; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Oxybate; Synaptic Membranes | 1987 |
GABA receptors on the cell-body membrane of an identified insect motor neuron.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Chlorides; Cockroaches; Dibenzazepines; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Potentials; Microelectrodes; Motor Neurons; Nipecotic Acids; Periplaneta; Picrotoxin; Receptors, GABA-A | 1988 |
CNS biochemical and pharmacological effects of the isomers of hexachlorocyclohexane (lindane) in the mouse.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Drug Synergism; Hexachlorocyclohexane; Ion Channels; Male; Mice; Motor Activity; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures | 1988 |
Blockade of gamma-aminobutyric acid-gated chloride current in frog sensory neurons by picrotoxin.
Topics: Animals; Anura; Chlorides; Electrophysiology; GABA Antagonists; Ion Channels; Mathematics; Neurons, Afferent; Picrotoxin | 1988 |
gamma-Aminobutyric acid-induced ion movements in the guinea pig hippocampal slice.
Topics: Animals; Bicuculline; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Picrotoxin; Potassium; Sodium; Tetrodotoxin | 1989 |
Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons.
Topics: Animals; Anti-Bacterial Agents; Bicuculline; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Macrolides; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Sesterterpenes; Spinal Cord | 1989 |
Pregnenolone sulfate antagonizes GABAA receptor-mediated currents via a reduction of channel opening frequency.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorides; Ion Channels; Membrane Potentials; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnenolone; Rats; Receptors, GABA-A | 1989 |
Acetylcholine and GABA mediate opposing actions on neuronal chloride channels in crayfish.
Topics: Acetylcholine; Animals; Astacoidea; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Neurons; Optic Lobe, Nonmammalian; Picrotoxin | 1989 |
Similarities between the effects of lindane (gamma-HCH) and picrotoxin on ligand-gated chloride channels in crayfish muscle membrane.
Topics: Animals; Astacoidea; Chlorides; gamma-Aminobutyric Acid; Hexachlorocyclohexane; In Vitro Techniques; Ion Channels; Muscles; Picrotoxin | 1989 |
Influence of GABA-gated bicarbonate conductance on potential, current and intracellular chloride in crayfish muscle fibres.
Topics: Animals; Astacoidea; Bicarbonates; Cell Membrane Permeability; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Mathematics; Membrane Potentials; Muscles; Picrotoxin | 1989 |
Functional chloride channels by mammalian cell expression of rat glycine receptor subunit.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Chlorides; DNA; Glycine; Humans; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Picrotoxin; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Recombinant Proteins; Strychnine; Transfection | 1989 |
The tremorigen aflatrem is a positive allosteric modulator of the gamma-aminobutyric acidA receptor channel expressed in Xenopus oocytes.
Topics: Allosteric Regulation; Animals; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Indoles; Membrane Proteins; Mycotoxins; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Xenopus | 1989 |
Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Dose-Response Relationship, Drug; Frontal Lobe; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Species Specificity; Synaptosomes | 1989 |
Chronic clonazepam administration decreases gamma-aminobutyric acidA receptor function in cultured cortical neurons.
Topics: Animals; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Clonazepam; Drug Administration Schedule; Flumazenil; Muscimol; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1989 |
An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells.
Topics: Acetylcholine; Action Potentials; Adrenal Medulla; Androstanes; Animals; Azasteroids; Bicuculline; Cattle; Cell Membrane; Chloride Channels; Chlorides; Chromaffin System; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Proteins; Picrotoxin; Propanidid; Receptors, Cholinergic; Receptors, GABA-A | 1989 |
Enhancement of benzodiazepine receptor binding by L-lysine is chloride-dependent and due to increase in binding affinity.
Topics: Animals; Cattle; Chlorides; Flunitrazepam; In Vitro Techniques; Kinetics; Lysine; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Synaptic Membranes | 1989 |
Bicuculline and picrotoxin block gamma-aminobutyric acid-gated Cl- conductance by different mechanisms.
Topics: Animals; Bicuculline; Binding, Competitive; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Picrotoxin; Rana catesbeiana | 1985 |
gamma Aminobutyric acid uptake, release, and effect on 36Cl--influx in bovine pineal gland.
Topics: Alanine; Aminooxyacetic Acid; Animals; Calcium; Cattle; Chlorides; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Nipecotic Acids; Picrotoxin; Pineal Gland; Potassium; Stimulation, Chemical | 1989 |
GABAA receptor complexes are present on both sides of a GABA-acceptive neuronal membrane.
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; Homeostasis; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A; Vestibular Nuclei; Vestibular Nucleus, Lateral | 1987 |
Pyrethroid insecticides and the gamma-aminobutyric acidA receptor complex: motor activity and the acoustic startle response in the rat.
Topics: Animals; Chlordiazepoxide; Chlorides; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Muscimol; Nitriles; Picrotoxin; Pyrethrins; Rats; Receptors, GABA-A; Reflex, Startle | 1987 |
Behavioral and functional studies indicate a role for GABAAergic transmission in the actions of ethanol.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred C57BL; Picrotoxin; Rats; Receptors, GABA-A; Seizures; Spinal Cord | 1987 |
Single subunits of the GABAA receptor form ion channels with properties of the native receptor.
Topics: Animals; Chloride Channels; Chlorides; Cloning, Molecular; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Macromolecular Substances; Membrane Proteins; Picrotoxin; Receptors, GABA-A; RNA, Messenger; Structure-Activity Relationship; Xenopus laevis | 1988 |
Direct evidence for the presence of GABAA receptors on the cytoplasmic side of the Deiters' neurone membrane.
Topics: Animals; Bicuculline; Chlorides; Cytoplasm; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A | 1988 |
Efflux of putative transmitters from superfused rat brain slices induced by low chloride ion concentrations.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Anions; Calcium; Cerebral Cortex; Chlorides; Female; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Rats; Rats, Inbred Strains; Serotonin; Strychnine; Tetrodotoxin | 1987 |
The picrotoxinin binding site and its relationship to the GABA receptor complex.
Topics: Acetates; Acetic Acid; Animals; Brain; Chlorides; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Picrotoxin; Rats; Receptors, GABA-A; Sesterterpenes; Sodium | 1985 |
Are the toxicities of pentobarbital and ethanol mediated by the GABA-benzodiazepine receptor-chloride ionophore complex?
Topics: Animals; Chlorides; Ethanol; Ionophores; Ketamine; Male; Mice; Organophosphorus Compounds; Pentobarbital; Picrotoxin; Pyrazoles; Receptors, GABA-A; Reflex; Strychnine | 1985 |
Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Flumazenil; Flunitrazepam; Ionophores; Male; Molecular Weight; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
[Ionic mechanisms of the effects of phenibut and GABA unrelated to changes in the function of chloride channels].
Topics: Animals; Anterior Horn Cells; Chlorides; Cyclic AMP; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Motor Neurons; Picrotoxin; Potassium; Rats; Receptors, GABA-A; Reflex; Sodium; Theophylline | 1985 |
Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes.
Topics: Amobarbital; Animals; Barbiturates; Bicuculline; Brain; Cell Membrane Permeability; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Hexobarbital; Male; Mephobarbital; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Rubidium; Secobarbital; Synapses | 1985 |
Neurotoxic insecticides inhibit GABA-dependent chloride uptake by mouse brain vesicles.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Insecticides; Male; Mice; Mice, Inbred ICR; Picrotoxin; Receptors, GABA-A | 1985 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
gamma-Aminobutyric acid-activated 36Cl- influx: a functional in vitro assay for CNS gamma-aminobutyric acid receptors of insects.
Topics: Animals; Bicuculline; Chlorides; Cockroaches; Electrophysiology; gamma-Aminobutyric Acid; Nervous System; Periplaneta; Picrotoxin; Receptors, GABA-A | 1987 |
Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain?
Topics: Adrenal Glands; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Male; Muscimol; Picrotoxin; Pregnenolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical | 1987 |
Cyclodiene insecticides inhibit GABAA receptor-regulated chloride transport.
Topics: Animals; Bicuculline; Biological Transport; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Insecticides; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Intracellular picrotoxin blocks pentobarbital-gated Cl- conductance.
Topics: Animals; Chlorides; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Microinjections; Pentobarbital; Picrotoxin; Rana catesbeiana | 1988 |
"Intracellular" GABA affects the equilibrium distribution of Cl- across the plasma membrane of a GABA acceptive neuron.
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; gamma-Aminobutyric Acid; Intracellular Membranes; Neurons; Picrotoxin; Time Factors; Vestibular Nucleus, Lateral | 1988 |
Biphasic responses of thalamic neurons to GABA in isolated rat brain slices--II.
Topics: Animals; Bicuculline; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Picrotoxin; Rats; Thalamus | 1988 |
GABA responses in rat dentate granule neurons are mediated by chloride.
Topics: Animals; Chlorides; Dendrites; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurons, Afferent; Pentobarbital; Picrotoxin; Rana catesbeiana | 1987 |
Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on GABA-mediated chloride uptake.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cerebral Cortex; Chlorides; Convulsants; Female; Furans; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Structure-Activity Relationship | 1987 |
Specific binding of 36Cl- ions to rat cerebellar membranes: effect of GABA and S-100 protein.
Topics: Animals; Bicuculline; Cerebellum; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Male; Membranes; Picrotoxin; Rats; Rats, Inbred Strains; S100 Proteins; Synaptic Membranes | 1987 |
A GABA-activated chloride-conductance not blocked by picrotoxin on spiny lobster neuromuscular preparations.
Topics: Action Potentials; Animals; Chlorides; Drug Resistance; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Muscimol; Nephropidae; Neuromuscular Junction; Picrotoxin; Species Specificity | 1986 |
Effects of gamma-aminobutyric acid on isolated cone photoreceptors of the turtle retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Photoreceptor Cells; Picrotoxin; Time Factors; Turtles | 1986 |
Actions of GABA and ethylenediamine on CA1 pyramidal neurones of the rat hippocampus.
Topics: Animals; Benzodiazepines; Bicuculline; Chlorides; Dendrites; Electric Conductivity; Ethylenediamines; gamma-Aminobutyric Acid; Hippocampus; Ion Exchange; Neurons; Osmolar Concentration; Picrotoxin; Potassium; Rats; Sodium | 1985 |
Effects of avermectin B1a and picrotoxin on striatal release of dopamine with reference to replacement of extracellular chloride with nitrate.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Chlorides; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Male; Nitrates; Picrotoxin; Rats; Rats, Inbred Strains; Tetrodotoxin; Verapamil | 1985 |
The ionic mechanism of action of GABA and L-glutamate on a crustacean striated muscle (vas deferens of the crayfish).
Topics: Aminobutyrates; Animals; Astacoidea; Chlorides; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Lithium; Male; Muscle Contraction; Muscles; Picrotoxin; Receptors, Drug; Sodium; Vas Deferens | 1974 |
Inhibitory miniature potentials in the stretch receptor neurons of crayfish.
Topics: Acetylcholine; Aminobutyrates; Animals; Chlorides; Crustacea; Membrane Potentials; Picrotoxin; Potassium Chloride; Sensory Receptor Cells; Synapses; Synaptic Transmission; Tetrodotoxin | 1969 |
The pharmacology and ionic dependency of amino acid responses in the frog spinal cord.
Topics: Action Potentials; Aminobutyrates; Animals; Anura; Chlorides; Glutamates; Glycine; In Vitro Techniques; Isoquinolines; Motor Neurons; Nerve Endings; Neural Inhibition; Neurons, Afferent; Picrotoxin; Rana pipiens; Sodium; Spinal Cord; Spinal Nerve Roots; Synapses; Synaptic Transmission | 1973 |
Early onset in inhibitory functions during synaptogenesis in fetal mouse brain cultures.
Topics: Alkaloids; Animals; Brain; Caffeine; Cerebral Cortex; Chlorides; Cyclic AMP; Dioxoles; Electric Stimulation; Evoked Potentials; Fetus; Hippocampus; Isoquinolines; Mice; Microelectrodes; Picrotoxin; Silver; Strychnine; Synapses | 1974 |
Primary afferent neurones: the ionic mechanism of GABA-mediated depolarization.
Topics: Aminobutyrates; Animals; Biological Transport, Active; Buffers; Chlorides; Ganglia, Spinal; In Vitro Techniques; Iontophoresis; Membrane Potentials; Nerve Endings; Neurons; Neurons, Afferent; Perfusion; Picrotoxin; Rana catesbeiana; Spinal Cord; Structure-Activity Relationship | 1974 |
Factors that affect the binding and uptake of gaba by brain tissue.
Topics: Acetylcholine; Aminobutyrates; Animals; Brain; Bromides; Cerebral Cortex; Cevanes; Chloral Hydrate; Chlorides; Chlorpromazine; Dopamine; Glutamates; Imipramine; Iodides; Lidocaine; Neostigmine; Norepinephrine; Ouabain; Phosphates; Picrotoxin; Procaine; Rats; Sodium Chloride; Tetrodotoxin | 1971 |
Effects of gamma-aminobutyric acid and picrotoxin on the permeability of the longitudinal muscle of the earthworm to various anions.
Topics: Aminobutyrates; Annelida; Bromides; Cell Membrane Permeability; Chlorides; Glutamates; Iodides; Membrane Potentials; Muscles; Picrotoxin | 1969 |
A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish.
Topics: Aminobutyrates; Animals; Chlorides; Crustacea; Depression, Chemical; Glutamates; Guanidines; Iontophoresis; Kinetics; Membrane Potentials; Neuromuscular Junction; Picrotoxin; Propionates; Receptors, Drug | 1969 |
Comparison of the actions of iontophoretically applied acetylcholine and gamma aminobutyric acid with the EPSP and IPSP in cockroach central neurons.
Topics: Acetylcholine; Aminobutyrates; Animals; Central Nervous System; Chlorides; Cockroaches; Dose-Response Relationship, Drug; Electric Stimulation; Gallamine Triethiodide; Ganglia; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; Microelectrodes; Neurons; Physostigmine; Picrotoxin; Potassium; Synapses | 1970 |
Evidence for association of a high affinity avermectin binding site with the benzodiazepine receptor.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cerebellar Cortex; Chlorides; Flunitrazepam; In Vitro Techniques; Ivermectin; Lactones; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Temperature | 1984 |
Avermectin modulation of GABA binding to membranes of rat brain, brine shrimp and a fungus, Mucor miehei.
Topics: Animals; Bicuculline; Brain; Chlorides; Decapoda; gamma-Aminobutyric Acid; Ivermectin; Kinetics; Lactones; Male; Mucor; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sodium | 1984 |
Effects of a neurotoxin in hornet venom on neuromuscular junctions of lobster.
Topics: 4-Aminobutyrate Transaminase; Animals; Bee Venoms; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Nephropidae; Neuromuscular Junction; Neurotoxins; Picrotoxin; Synaptic Membranes; Wasps | 1980 |
A novel effect of zinc on the lobster muscle GABA receptor.
Topics: Animals; Cations, Divalent; Chlorides; Ganglia, Sympathetic; Hydrogen-Ion Concentration; Ion Channels; Muscles; Nephropidae; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship; Zinc | 1982 |
Rat hippocampal neurons in culture: voltage-clamp analysis of inhibitory synaptic connections.
Topics: Animals; Chlorides; Culture Techniques; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Ion Channels; Kinetics; Membrane Potentials; Neural Inhibition; Neurons; Pentobarbital; Picrotoxin; Rats; Reaction Time; Synapses | 1984 |
Evidence for similarities between cyclodiene type insecticides and picrotoxinin in their action mechanisms.
Topics: Animals; Binding, Competitive; Chlorides; Cockroaches; Drug Resistance; gamma-Aminobutyric Acid; Heptachlor; Heptachlor Epoxide; Hexachlorocyclohexane; Male; Muscles; Periplaneta; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptosomes | 1983 |
Inhibition of transmitter release in bullfrog sympathetic ganglia induced by gamma-aminobutyric acid.
Topics: Acetylcholine; Action Potentials; Animals; Anura; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Sympathetic; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Picrotoxin; Potassium; Rana catesbeiana; Synapses; Synaptic Transmission | 1980 |
Effect of picrotoxin on benzodiazepine receptors and GABA receptors with reference to the effect of C1- ion.
Topics: Animals; Cerebellum; Chlorides; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Intracellular Membranes; Male; Models, Biological; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptosomes | 1981 |
Gaba induced excitatory responses in the guinea-pig small intestine are antagonized by bicuculline, picrotoxinin and chloride ion blockers.
Topics: Animals; Bicuculline; Chlorides; Diuretics; Female; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Myenteric Plexus; Picrotoxin; Sesterterpenes; Sulfonamides | 1981 |
A comparative study of avermectin B1a and other modulators of the gamma-aminobutyric acid receptor . chloride ion channel complex.
Topics: Animals; Anthelmintics; Benzodiazepines; Brain; Chlorides; Clonazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Male; Pentobarbital; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptic Membranes | 1982 |
Computer-assisted modeling of the picrotoxinin and gamma-butyrolactone receptor site.
Topics: 4-Butyrolactone; Chlorides; Computers; Furans; Ion Channels; Models, Chemical; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes | 1983 |
Binding of 3H-DMCM to benzodiazepine receptors; chloride dependent allosteric regulation mechanisms.
Topics: Animals; Anions; Carbolines; Cerebral Cortex; Chlorides; Etomidate; Indoles; Molecular Conformation; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes | 1983 |
Barbiturate and picrotoxin-sensitive chloride efflux in rat cerebral cortical synaptoneurosomes.
Topics: Animals; Barbiturates; Cerebral Cortex; Chlorides; Kinetics; Male; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synaptosomes | 1984 |
Alkyl-substituted gamma-butyrolactones inhibit [35S]TBPS binding to a GABA linked chloride ionophore.
Topics: 4-Butyrolactone; Animals; Barbiturates; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chlorides; Furans; gamma-Aminobutyric Acid; In Vitro Techniques; Ionophores; Male; Membranes; Picrotoxin; Rats; Rats, Inbred Strains | 1984 |
Effects of intracellular injections of chloride and EGTA on postepileptiform-burst hyperpolarizations in hippocampal neurons.
Topics: Animals; Chlorides; Egtazic Acid; Ethylene Glycols; Guinea Pigs; Hippocampus; Neurons; Penicillins; Picrotoxin; Seizures | 1981 |
SL 75 102 as a gama-aminobutyric acid agonist: experiments on dorsal root ganglion neurones in vitro.
Topics: Animals; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Guinea Pigs; In Vitro Techniques; Neurons; Picrotoxin | 1981 |
Biphasic response of hippocampal pyramidal neurons to GABA.
Topics: Animals; Chlorides; Cobalt; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Iontophoresis; Membrane Potentials; Neurons; Picrotoxin; Rats; Tetrodotoxin | 1981 |
A glutamate-activated chloride conductance on a crustacean muscle.
Topics: Animals; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Ibotenic Acid; Membrane Potentials; Nephropidae; Neural Inhibition; Neuromuscular Junction; Picrotoxin | 1981 |
Two components of inhibitory postsynaptic potentials evoked in hypoglossal motoneurons by lingual nerve stimulation.
Topics: Animals; Cats; Chlorides; Electric Stimulation; Evoked Potentials; Hypoglossal Nerve; Lingual Nerve; Mandibular Nerve; Motor Neurons; Neural Inhibition; Picrotoxin; Strychnine; Synapses | 1980 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Enhancement by GABA of the association rate of picrotoxin and tert-butylbicyclophosphorothionate to the rat cloned alpha 1 beta 2 gamma 2 GABAA receptor subtype.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Chlorides; Cloning, Molecular; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Kidney; Kinetics; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, GABA-A | 1995 |
Effects of plant diterpenes on the neuronal GABAA receptor-operated chloride current.
Topics: Abietanes; Animals; Chlorides; Diterpenes; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Kinetics; Neurons, Afferent; Osmolar Concentration; Picrotoxin; Plant Extracts; Rana catesbeiana; Receptors, GABA | 1994 |
GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Astrocytes; Bicuculline; Brain; Calcium; Calcium Channels; Carbolines; Cell Separation; Chlorides; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Gene Expression; Glial Fibrillary Acidic Protein; Hippocampus; Immunoblotting; In Vitro Techniques; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscimol; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
A novel GABA receptor modulates synaptic transmission from bipolar to ganglion and amacrine cells in the tiger salamander retina.
Topics: Animals; Calcium; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; Light; Neurotransmitter Agents; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Synaptic Transmission; Urodela | 1994 |
Patch-clamp recordings reveal powerful GABAergic inhibition in dentate hilar neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chlorides; Electrophysiology; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Neurons; Picrotoxin; Pyridazines; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Tetrodotoxin; Time Factors | 1994 |
The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one induces cytoarchitectural regression in cultured fetal hippocampal neurons.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Cell Death; Cell Division; Cell Survival; Cells, Cultured; Chlorides; Estradiol; Fetus; Hippocampus; Isomerism; Kinetics; Neurites; Neurons; Picrotoxin; Pregnanolone; Progesterone; Rats; Time Factors | 1994 |
Age-related changes of GABA-activated chloride channel properties in brain cortex synaptic plasma membrane: evidence for phospholipase involvement.
Topics: Aging; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Diglycerides; gamma-Aminobutyric Acid; Kinetics; Muscimol; Phospholipases; Picrotoxin; Rats; Rats, Wistar; Sulfur Radioisotopes; Synaptic Membranes; Synaptosomes | 1994 |
[The effect of picrotoxin and bicuculline on desensitization of the GABA receptor/Cl-ionophore complex].
Topics: Animals; Bicuculline; Biological Transport; Chlorides; GABA Antagonists; Ionophores; Male; Picrotoxin; Rats | 1994 |
Excitatory action of gamma-aminobutyric acid (GABA) on crustacean neurosecretory cells.
Topics: Action Potentials; Animals; Astacoidea; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Eye; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Microinjections; Neurites; Neurosecretory Systems; Picrotoxin; Synapses | 1994 |
The cell surface progesterone receptor which stimulates calcium influx in human sperm is unlike the A ring reduced steroid site on the GABAA receptor/chloride channel.
Topics: Acrosome; Binding Sites; Calcium; Chloride Channels; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Male; Pentobarbital; Picrotoxin; Progesterone; Receptors, GABA; Receptors, Progesterone; Spermatozoa | 1994 |
Fast presynaptic GABAA receptor-mediated Cl- conductance in cultured rat hippocampal neurones.
Topics: Animals; Bicuculline; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lidocaine; Neurons; Picrotoxin; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Presynaptic; Synapses; Synaptic Transmission; Tetrodotoxin | 1994 |
Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chlorides; Endosulfan; Female; gamma-Aminobutyric Acid; Insecticides; Mice; Pentylenetetrazole; Picrotoxin; Pregnancy; Receptors, GABA-A; Sesterterpenes | 1994 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
Ions required for the electrogenic transport of GABA by horizontal cells of the catfish retina.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Catfishes; Chlorides; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Intracellular Fluid; Ion Transport; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Picrotoxin; Retina; Sodium | 1993 |
Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons.
Topics: 4-Butyrolactone; Animals; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Neurons; Picrotoxin; Rats; Reaction Time | 1993 |
Ionic flux contributions to neocortical slow waves and nucleus basalis-mediated activation: whole-cell recordings in vivo.
Topics: Action Potentials; Animals; Auditory Cortex; Cesium; Chlorides; Electric Stimulation; Electrophysiology; Evoked Potentials; Picrotoxin; Potassium; Rats; Substantia Innominata; Synapses; Thalamus | 1993 |
Reconstitution of purified GABAA receptors: ligand binding and chloride transporting properties.
Topics: Animals; Bicuculline; Biological Transport; Brain Chemistry; Cattle; Chlorides; Chromatography, Affinity; Dose-Response Relationship, Drug; Flow Injection Analysis; Flunitrazepam; Ligands; Liposomes; Membrane Proteins; Muscimol; Picrotoxin; Quinolinium Compounds; Receptors, GABA-A | 1994 |
GABA-activated chloride channels in secretory nerve endings.
Topics: Animals; Bicuculline; Chlordiazepoxide; Chloride Channels; Chlorides; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Membrane Proteins; Muscimol; Nerve Endings; Picrotoxin; Pituitary Gland, Posterior; Rats; Receptors, GABA-A | 1993 |
Antagonist inhibition of GABAA-mediated chloride uptake is atypical in nigrocollicular areas.
Topics: Animals; Bicuculline; Brain; Chlorides; Chlorine; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inferior Colliculi; Ionophores; Kinetics; Male; Picrotoxin; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stimulation, Chemical; Substantia Nigra; Superior Colliculi | 1993 |
Slow and fast synaptic inhibition evoked by pattern-generating neurons of the gastric mill network in spiny lobsters.
Topics: Action Potentials; Animals; Chlorides; Evoked Potentials; Nephropidae; Neural Inhibition; Neurons; Picrotoxin; Potassium; Pylorus; Synaptic Transmission; Time Factors | 1995 |
The mechanism by which NBQX enhances NMDA currents in retinal ganglion cells.
Topics: Animals; Chlorides; Electric Conductivity; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Light; N-Methylaspartate; Neurotransmitter Agents; Picrotoxin; Quinoxalines; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Strychnine; Sucrose; Synaptic Transmission; Urodela | 1996 |
Signaling pathway downstream of GABAA receptor in the growth cone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Axons; Binding Sites; Calcium; Chlorides; Diazepam; Fetus; gamma-Aminobutyric Acid; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Neurological; Muscimol; Myristoylated Alanine-Rich C Kinase Substrate; Neurites; Picrotoxin; Prosencephalon; Proteins; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Verapamil | 1996 |
Expression of native GABAA receptors in Xenopus oocytes injected with rat brain synaptosomes.
Topics: Anesthetics; Animals; Brain; Cell Membrane; Chloride Channels; Chlorides; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Rats; Receptors, GABA-A; Synaptosomes; Xenopus laevis; Zinc Compounds | 1996 |
Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons.
Topics: Animals; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Pregnancy; Prohibitins; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.
Topics: Anesthetics; Animals; Binding Sites; Chlorides; Etomidate; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1997 |
Two types of identified ascending interneurons with distinct GABA receptors in the crayfish terminal abdominal ganglion.
Topics: Animals; Astacoidea; Bicuculline; Chlorides; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; In Vitro Techniques; Interneurons; Male; Muscimol; Muscles; Picrotoxin; Receptors, GABA | 1997 |
GABA(A) receptor activation triggers a Cl- conductance increase and a K+ channel blockade in cerebellar granule cells.
Topics: Animals; Barium; Bicuculline; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Receptors, GABA-A; Time Factors | 1997 |
Interactions of the neurosteroid dehydroepiandrosterone sulfate with the GABA(A) receptor complex reveals that it may act via the picrotoxin site.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebellum; Cerebral Cortex; Chlorides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Transport; Male; Mice; Mice, Inbred C57BL; Picrotoxin; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1997 |
Changes in the properties of developing glycine receptors in cultured mouse spinal neurons.
Topics: Animals; Cells, Cultured; Central Nervous System Depressants; Chlorides; Ethanol; Female; GABA Antagonists; Glycine; Glycine Agents; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Pregnancy; Receptors, Glycine; Spinal Cord; Strychnine; Synapses; Zinc | 1998 |
Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors.
Topics: Animals; Chlorides; Female; gamma-Aminobutyric Acid; Humans; Leucine; Mutagenesis, Site-Directed; Oocytes; Organophosphorus Compounds; Picrotoxin; Receptors, GABA; Xenopus laevis | 1998 |
Inhibitory connections between antagonistic motor neurones of the crayfish walking legs.
Topics: 3-Mercaptopropionic Acid; Acetylcholine; Action Potentials; Animals; Astacoidea; Chlorides; Electrophysiology; Female; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Immunoenzyme Techniques; Male; Microscopy, Electron; Motor Neurons; Neural Inhibition; Picrotoxin; Synapses; Tetraethylammonium; Tetrodotoxin; Walking | 1998 |
Multiple picrotoxinin effect on glycine channels in rat hippocampal neurons.
Topics: Action Potentials; Animals; Chloride Channels; Chlorides; GABA Antagonists; Hippocampus; Ion Transport; Ionophores; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Sesterterpenes | 1998 |
Glycine induces a novel form of long-term potentiation in the superficial layers of the superior colliculus.
Topics: Animals; Calcium Channels; Carbonates; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; Glycine; Glycine Agents; Guinea Pigs; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; Picrotoxin; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Strychnine; Superior Colliculi | 1998 |
GABAC receptor rho subunits are heterogeneously expressed in the human CNS and form homo- and heterooligomers with distinct physical properties.
Topics: Animals; Brain Chemistry; Cells, Cultured; Cerebellum; Chlorides; Cloning, Molecular; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Humans; Ion Channel Gating; Kidney; Mammals; Neurons; Picrotoxin; Protein Conformation; Receptors, GABA; Recombinant Fusion Proteins; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection | 1999 |
A reexamination of the role of GABA in the mammalian suprachiasmatic nucleus.
Topics: Action Potentials; Animals; Bicuculline; Cell Membrane Permeability; Chlorides; Circadian Rhythm; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gramicidin; In Vitro Techniques; Male; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Suprachiasmatic Nucleus | 1999 |
Inhibition of GABA-gated chloride channels by 12,14-dichlorodehydroabietic acid in mammalian brain.
Topics: Abietanes; Amphotericin B; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Diterpenes; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; Phenanthrenes; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1999 |
Cl- accumulation does not account for the depolarizing phase of the synaptic GABA response in hippocampal pyramidal cells.
Topics: Animals; Chlorides; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Synapses | 1999 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
Excitotoxic cell death dependent on inhibitory receptor activation.
Topics: Action Potentials; Animals; Bicuculline; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebellar Cortex; Chick Embryo; Chloride Channels; Chlorides; Excitatory Amino Acid Agonists; GABA Antagonists; Glycine; Ion Channel Gating; Ion Transport; Kainic Acid; Neuroprotective Agents; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glycine; Retina; Strychnine | 1999 |
Spontaneous and locomotor-related GABAergic input onto primary afferents in the neonatal rat.
Topics: Action Potentials; Afferent Pathways; Animals; Animals, Newborn; Bicuculline; Brain Stem; Chlorides; Decerebrate State; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Motor Activity; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Spinal Nerve Roots | 2000 |
GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Pregnanediones; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Axonal stratification patterns and glutamate-gated conductance mechanisms in zebrafish retinal bipolar cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Chlorides; Cycloleucine; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Neurons; Picrotoxin; Retina; Strychnine; Zebrafish | 2000 |
Physiology and pharmacology of native glycine receptors in developing rat ventral tegmental area neurons.
Topics: Age Factors; Animals; Anti-Bacterial Agents; Chloride Channels; Chlorides; GABA Antagonists; Glycine; Glycine Agents; Gramicidin; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Strychnine; Ventral Tegmental Area | 2000 |
The taurine uptake inhibitor guanidinoethyl sulphonate is an agonist at gamma-aminobutyric acid(A) receptors in cultured murine cerebellar granule cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebellar Cortex; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Agonists; Intracellular Fluid; Membrane Potentials; Mice; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Taurine; Time Factors | 2000 |
A role for chloride in the hyperpolarizing effect of acetylcholine in isolated frog vestibular hair cells.
Topics: Acetylcholine; Animals; Cats; Chloride Channels; Chlorides; Hair Cells, Auditory; In Vitro Techniques; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Rana pipiens; RNA, Messenger; Stilbenes | 2000 |
Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.
Topics: Animals; Behavior, Animal; Bumetanide; Carrier Proteins; Cells, Cultured; Chlorides; Contraindications; Female; GABA Antagonists; GABA-A Receptor Antagonists; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Ganglia, Spinal; Gramicidin; Male; Membrane Potentials; Mice; Mice, Knockout; Neurons; Pain Measurement; Patch-Clamp Techniques; Picrotoxin; Potassium; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters | 2000 |
Synaptic currents generating the inhibitory surround of ganglion cells in the mammalian retina.
Topics: Action Potentials; Animals; Chlorides; Dendrites; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Light; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Photic Stimulation; Picrotoxin; Potassium; Rabbits; Receptors, GABA; Receptors, GABA-A; Receptors, Glycine; Retina; Retinal Ganglion Cells; Sesterterpenes; Sodium; Synapses; Synaptic Transmission; Tetrodotoxin | 2001 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
Relative contributions of bipolar cell and amacrine cell inputs to light responses of ON, OFF and ON-OFF retinal ganglion cells.
Topics: Ambystomatidae; Animals; Chlorides; Electric Conductivity; Ganglia, Sensory; Imidazoles; Microscopy, Confocal; Patch-Clamp Techniques; Picrotoxin; Retina; Strychnine; Synaptic Transmission; Vision, Ocular | 2002 |
Pharmacological characterization of glycine-gated chloride currents recorded in rat hippocampal slices.
Topics: Age Factors; Animals; Chloride Channels; Chlorides; GABA Antagonists; Glycine; Glycine Agents; Hippocampus; Interneurons; Ion Channel Gating; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Strychnine; Taurine; Zinc | 2002 |
Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.).
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sea Bream | 2002 |
GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons.
Topics: Animals; Calcium; Calcium Channels; Cell Separation; Cells, Cultured; Chloride Channels; Chlorides; Drosophila; Drosophila Proteins; Embryo, Nonmammalian; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Receptors, GABA; Receptors, GABA-A; Synaptic Transmission; Time Factors | 2003 |
INHIBITORY POSTSYNAPTIC POTENTIALS IN GRASSHOPPER MUSCLE.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Grasshoppers; Inhibitory Postsynaptic Potentials; Insecta; Muscles; Neuromuscular Junction; Physiology; Picrotoxin; Research | 1964 |
CARDIAC EFFECTS OF DIMEFLINE COMPARED WITH THOSE OF OTHER CENTRAL NERVOUS SYSTEM STIMULANTS.
Topics: Aminobutyrates; Bemegride; Benzene; Calcium; Central Nervous System Stimulants; Chlorides; Coronary Vessels; Electrocardiography; Epinephrine; Flavones; Flavonoids; Guinea Pigs; Heart; Nikethamide; Pentylenetetrazole; Pharmacology; Picrotoxin; Research; Seizures; Strychnine; Toxicology; Ventricular Fibrillation | 1964 |
EXP-1 is an excitatory GABA-gated cation channel.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; Antigens, Protozoan; Barium Compounds; Bicuculline; Caenorhabditis elegans; Cations; Chloride Channels; Chlorides; Cloning, Molecular; Dose-Response Relationship, Drug; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglionic Blockers; Gastrointestinal Tract; Green Fluorescent Proteins; Humans; Ion Channel Gating; Luminescent Proteins; Mecamylamine; Membrane Potentials; Molecular Sequence Data; Muscle Contraction; Muscles; Mutagenesis, Site-Directed; Neuromuscular Junction; Oocytes; Patch-Clamp Techniques; Phylogeny; Picrotoxin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sodium; Transfection; Xenopus laevis | 2003 |
Bicuculline-insensitive GABA-gated Cl- channels in the larval nervous system of the moth Manduca sexta.
Topics: Animals; Bicuculline; Chloride Channels; Chlorides; Drosophila; Drosophila Proteins; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Immunohistochemistry; In Vitro Techniques; Ion Channel Gating; Isoquinolines; Isotopes; Larva; Manduca; Nervous System; Neurons; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Time Factors | 2003 |
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
Topics: Animals; Bicuculline; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Ionophores; Membrane Potentials; Microscopy, Electron, Transmission; Models, Neurological; Neural Inhibition; Neurons; Nystatin; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Presynaptic Terminals; Pyridines; Quinoxalines; Retina; Time Factors; Valine | 2004 |
Propofol effects on excitatory synaptic efficacy in the CA1 region of the developing hippocampus.
Topics: Age Factors; Animals; Animals, Newborn; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Long-Term Synaptic Depression; Patch-Clamp Techniques; Picrotoxin; Propofol; Rats; Rats, Wistar; Synaptic Transmission; Time Factors | 2005 |
Molecular weight and subunit composition of the sensitive to GABA-ergic ligands Cl-/HCO3(-)-stimulated Mg2+-ATPase from plasma membrane of rat brain.
Topics: Animals; Bicarbonates; Bicuculline; Brain; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Chlorides; Chromatography, Gel; Electrophoresis, Gel, Two-Dimensional; gamma-Aminobutyric Acid; Molecular Weight; Picrotoxin; Protein Subunits; Rats; Receptors, GABA-A | 2005 |
Actions of glutamate and ivermectin on the pharyngeal muscle of Ascaridia galli: a comparative study with Caenorhabditis elegans.
Topics: Action Potentials; Animals; Antinematodal Agents; Ascaridia; Caenorhabditis elegans; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ivermectin; Membrane Potentials; Pharyngeal Muscles; Picrotoxin; Species Specificity | 2006 |
The chloride transporter Na(+)-K(+)-Cl- cotransporter isoform-1 contributes to intracellular chloride increases after in vitro ischemia.
Topics: Animals; Brain Ischemia; Bumetanide; Chlorides; Culture Media; Furosemide; Glucose; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Picrotoxin; Recombinant Fusion Proteins; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2006 |
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bumetanide; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycolates; Ion Channels; Mice; Mice, Inbred C57BL; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Nitrobenzoates; Patch-Clamp Techniques; Phloretin; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Quinine; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Somatosensory Cortex; Tetrodotoxin | 2007 |
Characteristics of GABA receptors on the ocellar L-neurons of American cockroach Periplaneta americana.
Topics: Animals; Bicuculline; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Membrane Potentials; Muscimol; Neurons; Periplaneta; Picrotoxin; Receptors, GABA; Sodium Chloride | 2007 |
Chloride accumulation drives volume dynamics underlying cell proliferation and migration.
Topics: Acetates; Analysis of Variance; Bumetanide; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Size; Chlorides; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glioblastoma; Green Fluorescent Proteins; Humans; Imaging, Three-Dimensional; Indenes; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Sodium Potassium Chloride Symporter Inhibitors; Transfection | 2009 |
Synchronization of GABAergic inputs to CA3 pyramidal cells precedes seizure-like event onset in juvenile rat hippocampal slices.
Topics: Aging; Animals; CA3 Region, Hippocampal; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Intracellular Space; Magnesium Deficiency; Male; Periodicity; Picrotoxin; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Seizures; Synapses; Synaptic Transmission; Time Factors | 2009 |
Effect of zinc chloride on picrotoxin-induced hyperkinesis depends on its concentration in solution injected into rat neostriatum.
Topics: Animals; Chlorides; Drug Synergism; GABA Antagonists; Hyperkinesis; Male; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Zinc Compounds | 2011 |
Presynaptic NMDA receptor-mediated modulation of excitatory neurotransmission in the mouse dorsal motor nucleus of the vagus.
Topics: Animals; Biophysics; Chlorides; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamates; In Vitro Techniques; Male; Medulla Oblongata; Mice; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Vagus Nerve; Valine; Zinc Compounds | 2012 |
Blocking retinal chloride co-transporters KCC2 and NKCC: impact on direction selective ON and OFF responses in the rat's nucleus of the optic tract.
Topics: Animals; Bumetanide; Chlorides; Darkness; Female; Furosemide; Homeostasis; K Cl- Cotransporters; Light; Male; Photic Stimulation; Picrotoxin; Rats; Rats, Long-Evans; Retina; Sodium-Potassium-Chloride Symporters; Symporters; Visual Pathways | 2012 |
Gating effects on picrotin block of glycine receptors.
Topics: Amino Acid Substitution; Animals; Arginine; Chloride Channels; Chlorides; Dimerization; Dose-Response Relationship, Drug; Glycine; HEK293 Cells; Humans; Inhibitory Concentration 50; Ion Channel Gating; Lysine; Mutation, Missense; Patch-Clamp Techniques; Picrotoxin; Point Mutation; Protein Structure, Tertiary; Rats; Receptors, Glycine; Recombinant Fusion Proteins; Sesterterpenes; Transfection | 2012 |
A Chemogenetic Receptor That Enhances the Magnitude and Frequency of Glycinergic Inhibitory Postsynaptic Currents without Inducing a Tonic Chloride Flux.
Topics: Animals; Brain; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Embryo, Mammalian; GABA Antagonists; Glycine; Green Fluorescent Proteins; HEK293 Cells; Humans; Inhibitory Postsynaptic Potentials; Insecticides; Mutation; Neurons; Picrotoxin; Rats; Receptors, Glycine; Synapses; Transfection | 2017 |
A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
Topics: Animals; Bacterial Proteins; Cell Membrane; Chlorides; Etomidate; Extracellular Space; gamma-Aminobutyric Acid; Humans; Ligand-Gated Ion Channels; Membrane Potentials; Mutation; Neurotransmitter Agents; Oocytes; Pentobarbital; Picrotoxin; Propofol; Protein Domains; Protons; Receptors, GABA-B; Recombinant Fusion Proteins; Xenopus laevis | 2017 |
Inhibition of hypoglossal motoneurons by stimulation of the jaw-opening muscle afferents.
Topics: Animals; Cats; Chlorine; Electric Stimulation; Evoked Potentials; Hypoglossal Nerve; Mandibular Nerve; Motor Neurons; Neural Inhibition; Neurons, Afferent; Picrotoxin; Strychnine | 1975 |
Volatile anesthetics gate a chloride current in postnatal rat hippocampal neurons.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anesthetics; Animals; Animals, Newborn; Bicuculline; Chlorine; Chromatography, Gas; Culture Techniques; Dose-Response Relationship, Drug; Electrophysiology; Enflurane; gamma-Aminobutyric Acid; Halothane; Hippocampus; Ion Channel Gating; Isoflurane; Neurons; Picrotoxin; Rats; Sesterterpenes; Strychnine | 1992 |
Are GABAB receptors involved in the pharmacological effects of ethanol?
Topics: Animals; Baclofen; Cells, Cultured; Chlorine; Diazepam; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Picrotoxin; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Spinal Cord | 1990 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Studies on picrotoxin binding sites of GABAA receptors in rat cortical synaptoneurosomes.
Topics: Animals; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorine; Desoxycorticosterone; Diazepam; In Vitro Techniques; Male; Membranes; Muscimol; Pentobarbital; Picrotoxin; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids; Synaptosomes | 1994 |
Drosophila mushroom body Kenyon cells generate spontaneous calcium transients mediated by PLTX-sensitive calcium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Analysis of Variance; Animals; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Chlorine; Cobalt; Curare; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drosophila; Drug Combinations; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Iodine; Mushroom Bodies; Neurons; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Phenols; Picrotoxin; Pupa; Salicylates; Spider Venoms; Tetrodotoxin; Thapsigargin; Time Factors; Valine | 2005 |
Chloride currents in cones modify feedback from horizontal cells to cones in goldfish retina.
Topics: Action Potentials; Animals; Chloride Channels; Chlorine; Feedback, Physiological; GABA Antagonists; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Goldfish; Models, Neurological; Picrotoxin; Retinal Cone Photoreceptor Cells; Retinal Horizontal Cells; Synaptic Transmission | 2012 |