picrotoxin has been researched along with bicuculline in 881 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 417 (47.33) | 18.7374 |
| 1990's | 279 (31.67) | 18.2507 |
| 2000's | 147 (16.69) | 29.6817 |
| 2010's | 35 (3.97) | 24.3611 |
| 2020's | 3 (0.34) | 2.80 |
| Authors | Studies |
|---|---|
| Segal, M | 1 |
| Haefely, W; Polc, P | 1 |
| Kerkut, GA; Piggott, SM; Walker, RJ | 1 |
| Javid, MJ; Stone, WE | 2 |
| Barman, SM; Gebber, GL | 1 |
| Bernardo, K; Keenan, L; Koopowitz, H | 1 |
| Yessaian, NH | 1 |
| King, GA | 1 |
| Hamberger, A; Sellström, A | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 2 |
| Battista, AF; Goldstein, M; Miyamoto, T | 1 |
| Enna, SJ; Snyder, SH | 1 |
| Schechter, PJ; Tranier, Y | 1 |
| DeFeudis, FV | 1 |
| Frederickson, RC; McBride, WJ; Morzorati, SL; Neuss, M | 1 |
| Chappell, RL; Klingman, A | 1 |
| Martin, IL; Mitchell, PR | 1 |
| Hendelman, WJ; Marshall, KC; Wojtowicz, JM | 1 |
| Davidoff, RA; Hackman, JC; Osorio, I | 2 |
| Arbilla, S; Langer, SZ | 1 |
| Brennan, MJ; Cantrill, RC | 1 |
| Matthews, WD; McCafferty, GP | 1 |
| Pletscher, A; Saner, A | 1 |
| Aschan, G; Larsby, B; Odkvist, LM; Tham, R | 1 |
| Stone, WE | 1 |
| Kudo, Y | 1 |
| Rose, D | 1 |
| Ciesielski, L; Kempf, E; Mack, G; Maitre, M; Mandel, P; Simler, S | 1 |
| Bioulac, B; de Tinguy-Moreaud, E; Neuzil, E; Vincent, JD | 1 |
| Risley, EA; Williams, M | 1 |
| Franco, S; Schlosser, W | 2 |
| Barnes, CD; Polzin, RL | 1 |
| Betti, R; Cocchi, D; Frigerio, C; Krogsgaard-Larsen, P; Locatelli, V; Müller, EE; Racagni, G | 1 |
| Den Breejen, EJ; Mulder, AH; Stoof, JC | 1 |
| Kirby, AW | 1 |
| Homma, S | 1 |
| Crepel, F; Delhaye-Bouchaud, N; Dupont, JL | 1 |
| Constanti, A | 2 |
| Boissier, JR; Dumont, C; Oberlander, C | 1 |
| Barker, JL; Macdonald, RL | 1 |
| Di Chiara, G; Gessa, GL; Morelli, M; Porceddu, ML | 1 |
| Di Chiara, G; Gessa, GL; Morelli, M; Mulas, ML; Porceddu, ML | 1 |
| Arnt, J; Scheel-Krüger, J | 1 |
| Bigler, ED | 1 |
| Gartside, IB; Hayes, AG; Straughan, DW | 1 |
| Plourde, G; Tremblay, JP | 1 |
| Felpel, LP | 1 |
| Feldberg, W; Rocha e Silva, M | 1 |
| Evans, RH | 1 |
| Greenlee, D; Olsen, RW; Ticku, MK; Van Ness, PC | 1 |
| Kaplan, BJ; Williamson, PD | 1 |
| Piatigorskiĭ, BIa; Pivnutel', RV | 1 |
| Gallagher, JP; Higashi, H; Nishi, S | 1 |
| Coote, JH; Sato, A | 1 |
| Carpenter, DO; Yarowsky, J | 1 |
| Homma, S; Rovainen, CM | 1 |
| Gower, M; MacNeil, D; Szymanska, I | 1 |
| Frey, HH; Löscher, W | 1 |
| Horng, JS; Wong, DT | 1 |
| Demirjian, AH; Tozalakian, BV; Yessaian, NH | 1 |
| Bartholini, G; Stadler, H | 1 |
| Klinke, R; Oertel, W | 1 |
| Davidson, N; Macfarlane, EI; Michie, DL | 1 |
| Dacheux, RF; Frumkes, TE; Miller, RF | 1 |
| Dupelj, M; Lee, KC; Wagner, A | 1 |
| Dill, RE; Standefer, MJ | 1 |
| Altmann, H; Pickelmann, P; Steinberg, R; Ten Bruggencate, G | 1 |
| Okamoto, K; Quastel, DM; Quastel, JH | 1 |
| Ben-Ari, Y; Dingledine, R; Kanazawa, I; Kelly, JS | 1 |
| Mulas, A; Pedata, F; Pepeu, G; Pepeu, IM | 1 |
| Enroth-Cugell, C; Kirby, AW | 1 |
| Bellin, SI; Edmonds, HL | 1 |
| Bornstein, MB; Corrigall, WA; Crain, SM | 1 |
| Starr, MS | 1 |
| Levy, RA | 1 |
| Nicoll, RA | 1 |
| Ban, M; Lee, JM; Olsen, RW | 1 |
| Dray, A | 1 |
| Gähwiler, BH | 1 |
| Bernardi, G; Giacomini, P; Marciani, MG; Morucutti, C | 1 |
| Fedinets, P; Kent, EW | 1 |
| Hara, N; Ichinose, M; Sawada, M | 1 |
| Pinnock, RD | 2 |
| Dean, P; Redgrave, P | 1 |
| Bartolini, A; Ghelardini, C; Giotti, A; Malcangio, M; Malmberg-Aiello, P | 1 |
| Golovko, AI; Sofronov, GA | 2 |
| Bonaventure, N; Jardon, B; Kim, MS; Yücel, H | 1 |
| Santiago, M; Westerink, BH | 1 |
| Moises, HC; Washburn, MS | 1 |
| Lin, WC; Watanabe, K; Yano, S | 3 |
| Iasnetsov, VV; Novikov, VE; Sharov, AN | 1 |
| Godlevskiĭ, LS; Oleĭnik, AA; Shandra, AA; Vikhrestiuk, SL | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Colquhoun, L; Holden-Dye, L; Walker, RJ | 1 |
| Arancibia, S; Benyassi, A; Rage, F; Tapia-Arancibia, L | 1 |
| Kawaguchi, Y | 1 |
| Aoki, S; Iwamoto, M; Jino, H; Kawaguchi, A; Kurahashi, K; Oikawa, H | 1 |
| Qian, H; Ripps, H | 2 |
| Dubrovina, NI; Finkelberg, AL; Ilyutchenok, RY; Loskutova, LV | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 2 |
| Arakawa, O; Nakahiro, M; Narahashi, T | 1 |
| MacDonald, RL; Twyman, RE | 1 |
| Lee, HH; Terada, M | 1 |
| Mizuki, Y; Sekimoto, M; Ushijima, I; Yamada, M | 1 |
| Habibuddin, M; Pal, M; Pal, SP | 1 |
| Asahara, T; Higuchi, K; Nishimura, Y; Tanaka, T | 1 |
| Goto, Y; Hara, N; Hara, Y; Yamasaki, K | 1 |
| Pencheva, N; Radomirov, R; Venkova, K | 1 |
| Slaughter, MM; Stockton, RA | 1 |
| Cupello, A; Hydén, H; Palm, A; Rapallino, MV | 1 |
| Agmo, A; Fernández, H | 1 |
| Aley, KO; Kulkarni, SK | 2 |
| Kow, LM; Ogawa, S; Pfaff, DW | 1 |
| Bitran, D; Kellogg, CK; Primus, RJ | 1 |
| Amit, Z; Koechling, UM; Smith, BR | 1 |
| Long, SK; van Wilgenburg, H; Wesselman, JP | 1 |
| Agmo, A; Gutiérrez, M; Guzmán, M; Pruneda, R | 1 |
| Johnston, D; Williams, SH | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ; Ward, RA | 1 |
| Bonanno, G; Fedele, E; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Araki, Y; Gomita, Y; Ichimaru, Y; Moriyama, M | 1 |
| Davidoff, RA; Hackman, JC | 1 |
| Engel, JA; Söderpalm, B | 1 |
| Aram, JA; Michelson, HB; Wong, RK | 1 |
| DiMicco, JA; Soltis, RP | 1 |
| Kitai, ST; Pennartz, CM | 1 |
| Kubota, M; Saito, N | 1 |
| Ichihara, K; Kameyama, T; Nabeshima, T; Tohyama, K | 1 |
| Bowman, JW; Lee, BL; Thompson, DP; Whaley, HA | 1 |
| Cook, BJ; Cooper, JF; Wagner, RM | 1 |
| Burnham, WM; Mingo, NS | 1 |
| Kaneko, A; Suzuki, S; Tachibana, M | 1 |
| Allen, TG; Burnstock, G | 1 |
| Lothman, EW; Stringer, JL | 1 |
| Isenberg, KE; Yang, J; Zorumski, CF | 1 |
| Liljequist, S | 1 |
| Koffler-Smulevitz, D; Nichols, TR | 1 |
| Ariel, M; Rosenberg, AF | 1 |
| Godlevskiĭ, LS; Kryzhanovskiĭ, GN; Shandra, AA; Vikhrestiuk, SL | 1 |
| Lok, SY; Meldrum, BS; Millan, MH; Obrenovitch, TP; Sarna, GS; Symon, L | 1 |
| Ekström, P; Meissl, H | 1 |
| Berretta, S; Bosco, G; Perciavalle, V; Smecca, G | 1 |
| Faktorová, M; Kubová, H; Mares, P | 1 |
| Batini, C; Billard, JM | 1 |
| Muramatsu, S; Nagatsuka, Y; Niijima, K; Yoshida, M | 1 |
| Felder, RB; Feldman, PD | 1 |
| Leslie, JC; Shephard, RA; Toal, L | 1 |
| Waldrop, TG | 1 |
| Gatti, PJ; Gillis, RA | 1 |
| Cutler, MG; Moore, MR; Turner, JM | 1 |
| Arnoldi, A; Bonsignori, A; Melloni, P; Merlini, L; Quadri, ML; Varasi, M | 1 |
| Dillon, GH; Shonis, CA; Waldrop, TG | 1 |
| Arata, A; Homma, I; Onimaru, H | 1 |
| Iasnetsov, VS; Sizov, PI | 1 |
| Arancibia, S; Briozzo, P | 1 |
| Abdikaliev, NA; Mdzinarishvili, AL; Meerson, FZ; Pshennikova, MG; Voronina, TA | 1 |
| Atsuta, Y; Garcia-Rill, E; Ishikawa, Y; Kinjo, N; Skinner, RD; Webber, M | 1 |
| Kotak, VC; Page, CH | 1 |
| Akaike, N; Nakagawa, T; Nakaye, T; Shirasaki, T; Wakamori, M | 1 |
| Alhaider, AA; Lei, SZ; Wilcox, GL | 1 |
| Albertson, TE; Joy, RM | 2 |
| Sun, LS; Sun, QX; Tu, YJ; Wu, HB; Xiao, J | 1 |
| Mares, P; Rokyta, R; Velísek, L; Velísková, J | 1 |
| Coulter, DA; Huguenard, JR; Prince, DA | 1 |
| Manev, H; Pericić, D | 2 |
| Fincher, AS; Frye, GD; Griffith, WH; Lorenzetti, M; Trzeciakowski, J | 1 |
| DiMicco, JA; Hingtgen, JN; Shekhar, A | 1 |
| Jones, RS; Lambert, JD | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 2 |
| Batueva, IV; Suderevskaia, EI | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Kontro, P; Korpi, ER; Oja, SS | 1 |
| Artemenko, DP; Gerasimov, VD | 2 |
| Malchow, RP; Ripps, H | 1 |
| Jackson, H; Parks, TN | 1 |
| Slater, NT; Smith, RD; Turek, FW | 1 |
| Cupello, A; Hydén, H; Rapallino, MV | 2 |
| Carlen, PL; Spigelman, I; Zhang, L | 1 |
| Campbell, JA; Greenwood, TD; Rathman, TL; Sleevi, MC; Wolfe, JF | 1 |
| Itoh, J; Kameyama, T; Nabeshima, T; Noda, Y; Tohyama, K | 1 |
| Depaulis, A; Liu, Z; Marescaux, C; Micheletti, G; Vergnes, M; Warter, JM | 1 |
| Inoue, M; Matsuo, T; Ogata, N | 2 |
| Paul, SM; Schwartz, RD; Skolnick, P; Suzdak, PD | 1 |
| Aihara, H; Kurachi, M | 1 |
| Armstrong, WE; Sladek, CD | 1 |
| David, JA; Pinnock, RD; Sattelle, DB; Wafford, KA | 1 |
| Lux, HD; Misgeld, U; Müller, W | 1 |
| Fukuda, H; Matsumoto, K; Ono, H; Yamazaki, J | 1 |
| Callaway, JC; Stuart, AE | 1 |
| Dudek, BC; Phillips, TJ | 1 |
| Dudek, BC; Kim, D; Phillips, TJ | 1 |
| Hamilton, MS; Shephard, RA | 1 |
| Bobker, DH; Williams, JT | 1 |
| Sedlácek, J | 2 |
| Baes, M; Vale, WW | 1 |
| Golovenko, NIa; Zhuk, OV; Zin'kovskiĭ, VG | 3 |
| Kamei, J; Kasuya, Y; Ogawa, M | 1 |
| Crema, A; De Petris, G; Manzo, L; Onori, L; Rizzi, CA; Tonini, M | 1 |
| Barbier, AJ; Guenaneche, F; Lefebvre, RA | 1 |
| Ariel, M | 1 |
| Kerr, DI; Ong, J | 3 |
| Moguilewsky, M; Philibert, D; Shu, C; Vincens, M | 1 |
| Georgiev, V; Kambourova, T; Yonkov, D | 1 |
| Kaneyuki, H | 1 |
| Cottrell, GA; Lambert, JJ; Peters, JA | 1 |
| Gal'chenko, AA; Iarkov, AV; Kovalev, GI; Vorob'ev, VV | 1 |
| Pierson, MG; Smith, KL; Swann, JW | 1 |
| Alexandrov, AA; Batuev, AS; Chan, CA; Kcharazia, VN; Scheynikov, NA | 1 |
| Ben-Ari, Y; Cherubini, E; Corradetti, R; Gaiarsa, JL | 1 |
| Akaike, N; Carpenter, DO; Hattori, K; Oomura, Y | 1 |
| Allah-Maddadi, S; Hosseini-Nia, T; Zarrindast, MR | 1 |
| Caligaris, L; Haymal, B; Morello, H; Taleisnik, S | 1 |
| Fukuda, H; Ishikawa, M; Miyazaki, H | 1 |
| Pan, ZZ; Williams, JT | 1 |
| Suzuki, Y; Taguchi, K | 1 |
| Castellano, C; Introini-Collison, IB; McGaugh, JL; Pavone, F | 1 |
| Kulkarni, SK; Ticku, MK | 1 |
| Bhadra, S; Idemudia, SO; Lal, H | 1 |
| Carter, DA; Lightman, SL; Saridaki, E | 1 |
| Georgieva, J | 1 |
| Evans, RH; Krijzer, F; Long, SK | 1 |
| Aston-Jones, G; Ennis, M | 1 |
| Nakamura, J; Sasa, M; Takaori, S | 1 |
| Kirsch, M; Wagner, HJ | 1 |
| Cupello, A; Hydén, H; Palm, A | 2 |
| Akaike, N; Carpenter, DO; Tokutomi, N; Yakushiji, T | 2 |
| Asaro, D; Pellegrini, G; Pittaluga, A; Raiteri, M | 1 |
| Oveissi, Y; Zarrindast, MR | 1 |
| Maggi, CA; Meli, A; Santicioli, P | 1 |
| Castellano, C; Pavone, F | 1 |
| Golovenko, NIa; Zhuk, OV; Zin'kovskiiĭ, VG | 1 |
| Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC | 1 |
| Hara, S; Morioka, S; Satoh, K; Yanagihara, S | 1 |
| Mehta, AK; Ticku, MK | 2 |
| Itoh, K; Kameyama, T; Nabeshima, T; Noda, Y | 1 |
| Fujii, E; Nomoto, T | 1 |
| Connors, BW; Malenka, RC; Silva, LR | 1 |
| Bhargava, KP; Gupta, GP; Gupta, MB | 1 |
| Hata, H; Kido, N; Nakamura, T; Ohnishi, T; Tonoue, T | 1 |
| Gray, JA; Henney, S; Lawson, P; Mellanby, J; Quintero, S | 1 |
| Buckland, C; Gray, JA; McNaughton, N; Mellanby, J; Quintero, S | 1 |
| Nistri, A; Sivilotti, L | 2 |
| Gross, RA; Macdonald, RL; Weddle, MG | 1 |
| Kent, AP; Webster, RA | 1 |
| Anderson, MC; Chung, EY; Van Woert, MH | 1 |
| Fujiwara, M; Kurahashi, K; Okamoto, T; Tsubomura, T | 1 |
| Dingledine, R; Hynes, MA; King, GL | 1 |
| Garg, SK; Kulkarni, SK; Shukla, VK | 1 |
| McGarrick, JD; Stone, TW; Thexton, AJ | 1 |
| Jones, RS | 1 |
| Hara, T; Kawazawa, S; Mizuki, Y; Ushijima, I; Yamada, M | 1 |
| Chase, MH; Morales, FR; Soja, PJ | 1 |
| Boussaoud, D; Joseph, JP | 1 |
| Rastogi, SK; Ticku, MK | 1 |
| George, SR; Meissl, H | 1 |
| Giotti, A; Luzzi, S; Maggi, CA; Spagnesi, S; Zilletti, L | 1 |
| Humphrey, SJ; McCall, RB | 2 |
| Ho, IK; Sivam, SP | 2 |
| Scholfield, CN; Steel, L | 1 |
| DiMicco, JA; Wible, JH; Zerbe, RL | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Lelekova, TV; Serbeniuk, TsV | 2 |
| Georgiev, VP; Yonkov, DI | 1 |
| Gustafsson, B; Wigström, H | 2 |
| Durán, JA; Miñano, FJ; Sancibrián, M; Serrano, JS | 1 |
| Jackson, JA; Paul, SM; Schwartz, RD; Skolnick, P; Weigert, D | 1 |
| Barolet, AW; Li, A; Liske, S; Morris, ME | 1 |
| Agardh, E | 1 |
| Buckland, C; Gray, JA; Mellanby, J | 1 |
| Allan, AM; Harris, RA | 1 |
| Beyer, C; Fernández-Guasti, A; Larsson, K | 1 |
| Blessing, WW; Jervois, PM; Menadue, MF; Willoughby, JO | 1 |
| Biggio, G; Corda, MG | 1 |
| Little, HJ; Nutt, DJ; Taylor, SC | 1 |
| Croucher, M; Gueremy, C; Le Fur, G; Legrand, JJ; Mazadier, M; Meldrum, B; Mizoule, J; Ollat, C; Uzan, A | 1 |
| Beyer, C; Komisaruk, BR; Roberts, LA | 1 |
| Astier, H; Roussel, JP; Tapia-Arancibia, L | 2 |
| Barnard, EA; Bilbe, G; Brown, DA; Constanti, A; Houamed, K; Smart, TG; VanRenterghem, C | 1 |
| Kaufman, WR; Lindsay, PJ | 1 |
| Abalis, I; Eldefrawi, AT; Eldefrawi, ME; Sattelle, DB; Wafford, KA | 1 |
| Adjeroud, S; Bernard, C; Cazin, L; Danger, JM; Lamacz, M; Leneveu, E; Stoeckel, ME; Tappaz, ML; Tonon, MC; Vaudry, H | 1 |
| Simmonds, MA | 6 |
| Eldefrawi, AT; Eldefrawi, ME; Gant, DB | 1 |
| Herrera-Marschitz, M; Ungerstedt, U | 1 |
| Lindgren, S | 1 |
| Ossowska, K; Wardas, J; Wolfarth, S | 1 |
| DiMicco, JA; Shekhar, A | 1 |
| Dowling, JE; O'Connor, PM; Zucker, CL | 1 |
| Conzelmann, U; Meyer, DK | 1 |
| Anić-Stojiljković, S; Manev, H; Pericić, D | 1 |
| Kavaliers, M; Wiebe, JP | 1 |
| Klee, MR; Preisendörfer, U; Zeise, ML | 1 |
| Laporte, AM; Soubrié, P; Thiébot, MH | 1 |
| Bauer, RM; Iwamoto, GA; Waldrop, TG | 1 |
| Brioni, JD; McGaugh, JL | 1 |
| Kimura, H; Uemura, S | 1 |
| Frosch, MP; Lipton, SA; Tauck, DL | 1 |
| Djavdan, M; Zarrindast, MR | 1 |
| Johnston, GA; Kerr, DI; Ong, J | 1 |
| Larson-Prior, LJ; Slater, NT | 1 |
| Crabbe, JC; Feller, DJ; Harris, RA | 1 |
| Jancsó, G; Such, G | 1 |
| Ishita, S; Kato, S; Negishi, K; Shimada, Y; Teranishi, T | 1 |
| Lister, RG; Nutt, DJ | 1 |
| DiMicco, JA; Luft, FC; Wible, JH | 1 |
| Jones, MW; Kilpatrick, IC; Phillipson, OT | 1 |
| Besharse, JC; Pierce, ME | 1 |
| Haberly, LB; Tseng, GF | 1 |
| Thomson, AM | 1 |
| Milner, KL; Mogenson, GJ | 1 |
| Haley, DA; Madden, J; Thompson, RF | 1 |
| Gottlob, I; Tuppy, FK; Wündsch, L | 1 |
| Inenaga, K; Kannan, H; Kasai, M; Osaka, T; Yamashita, H | 1 |
| Burnod, Y; Hirsch, JC | 1 |
| Nagahama, T; Takata, M; Tomomune, N | 1 |
| Georgiev, V; Getova, D | 1 |
| Sakai, A; Sugimoto, T; Takemura, M | 1 |
| Bonaventure, N; Jardon, B; Wioland, N | 1 |
| Greene, RW; Haas, HL; Siegfried, J; van Loveren, HR | 1 |
| Budelli, R; González-Estrada, MT; Soto, E; Vega, R | 1 |
| Akasu, T; Ariyoshi, M | 1 |
| Akaike, N; Maruyama, T; Tokutomi, N | 1 |
| Fehér, O; Toldi, J | 2 |
| Gallagher, JP; Shinnick-Gallagher, P; Stevens, DR | 1 |
| Chase, MH; Finch, DM; Soja, PJ | 1 |
| Conte, B; Furio, M; Maggi, CA; Meli, A; Santicioli, P | 1 |
| Acs, Z; Kapócs, G; Makara, GB; Szabó, B | 1 |
| Evans, D; Smith, JC | 1 |
| Ong, J | 1 |
| Georgiev, V; Kambourova, T; Opitz, M; Yonkov, D | 1 |
| Cupello, A; Hydén, H | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Ishimaru, M; Sakai, A; Sugimoto, T; Takemura, M | 1 |
| Baranyi, A; Chase, MH; Morales, FR; Soja, PJ | 1 |
| Borsini, F; Evangelista, S; Meli, A | 1 |
| Fink, H; Morgenstern, R | 1 |
| Sano, M; Terada, M | 1 |
| Lakić, N; Manev, H; Pericić, D | 1 |
| Giuliani, S; Maggi, CA; Meli, A | 1 |
| Kaneko, A; Tachibana, M | 1 |
| Bapna, JS; Chandra, D; Lenin Kamatchi, G; Veeraragavan, K | 1 |
| Goddard, GV; Morimoto, K | 1 |
| Alpern, HP; McIntyre, TD | 1 |
| Fields, HL; Moreau, JL | 1 |
| Dohi, T; Kitayama, S; Koyama, Y; Morita, K; Tsujimoto, A | 1 |
| Kato, S; Negishi, K; Teranishi, T | 1 |
| Piredda, SG; Swinyard, EA; Woodhead, JH | 1 |
| Hinko, CN; Lee, JA; Moore, JA; Nicholson, JM; Scott, KR; Zalucky, TB | 1 |
| Chweh, AY; Coleman, JC; Shenoy, AK; Swinyard, EA | 1 |
| Calderazzo-Filho, LS; Cavalheiro, EA; Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA | 1 |
| Simmonds, MA; Turner, JP | 1 |
| Fitzgerald, JA; Garcia-Rill, E; Skinner, RD | 1 |
| Dolci, S; Eusebi, F; Siracusa, G | 1 |
| Cross, RS; Giesler, M; Nelson, SR; Pazdernik, TL; Samson, FE | 1 |
| Cohen, JL | 1 |
| Huang, CJ; Xiang, JZ | 1 |
| Blaxter, TJ; Cottrell, GA | 1 |
| Johns, KL; Wood, JD | 1 |
| Mori-Okamoto, J; Tatsuno, J | 1 |
| Gallo, V; Guidotti, A; Vaccarino, F; Wise, BC | 1 |
| Okubo, J; Sakai, A; Sugimoto, T; Takemura, M | 1 |
| Kurz-Isler, G; Wolburg, H | 1 |
| Girard, CL; Matte, JJ; Seoane, JR | 1 |
| Higashio, T; Inukai, T; Nakao, K | 1 |
| Thomson, AM; West, DC | 1 |
| Inagaki, C; Ishiko, J; Takaori, S | 1 |
| Bernardi, G; Giacomini, P; Marciani, MG; Morocutti, C | 1 |
| Stuart, AE; Timpe, LC | 1 |
| Calcott, PH; Fatig, RO | 1 |
| Leeb-Lundberg, LM; Olsen, RW; Snowman, AM; Wong, EH | 1 |
| Georgiev, V; Getova, D; Petkov, V | 1 |
| Langwiński, R; Matla, J | 1 |
| Drexler, G; Karobath, M; Supavilai, P | 1 |
| Gray, JA; Holt, L; McNaughton, N; Mellanby, J; Quintero, S | 1 |
| Andreev, BV; Ignatov, IuD | 1 |
| Kitazato, K; Toide, K; Unemi, N | 1 |
| Kendall, TJ; Minchin, MC | 1 |
| Champagnat, J; Denavit-Saubié, M; Moyanova, S; Rondouin, G | 1 |
| Goldstein, JM; Knobloch, LC; Malick, JB | 1 |
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| Davidoff, RA; Hackman, JC; Holohean, AM; Luetje, CW; Maddox, FN; Poth, K; Valeyev, AY; Wood, PM | 1 |
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| Bidziński, A; Członkowska, AI; Krzaścik, P; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Szyndler, J; Taracha, E; Turzyńska, D; Walkowiak, J; Wisłowska, A; Zienowicz, M | 1 |
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| Ojewole, JA | 4 |
| Cherubini, E; Conti, F; Fattorini, G; Safiulina, VF | 1 |
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| Chen, Z; Dai, H; Hu, W; Huang, Y; Leurs, R; Luo, J; Shen, Y; Timmerman, H; Zhang, Z; Zhu, Y | 1 |
| Feuerstein, TJ; Fuellgraf, H; Mantovani, M; Moser, A; Van Velthoven, V | 1 |
| Dhir, A; Kulkarni, SK; Naidu, PS | 1 |
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| Cervero, F; Garcia-Nicas, E; Laird, JM | 1 |
| Amabeoku, GJ; Ojewole, JA | 1 |
| Ghadimi, M; Ramezani-Tehrani, B; Sahebgharani, M; Zarrindast, MR | 1 |
| Eisenman, LN; Kress, G; Mennerick, S; Zorumski, CF | 1 |
| Hartmann, J; Hildmann, O; Kiewert, C; Klein, J; Kumar, V; Naik, RS; Rueda, M | 1 |
| Fu, LY; van den Pol, AN | 1 |
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| Manabe, T; Nakamura, M; Sekino, Y | 1 |
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| Fleming, RL; Swartzwelder, HS; Wilson, WA | 1 |
| Amin, J; Hadley, SH | 1 |
| Amabeoku, GJ; Green, I; Kabatende, J | 1 |
| Choi, D; Harris, RH; Kohn, H; Kupferberg, HJ; Stables, JP; Stöhr, T; Walton, N; White, HS | 1 |
| Kubová, H; Mares, P; Tchekalarova, J | 1 |
| Castro, M; Duarte, I; Francischi, J; Pacheco, D; Perez, A; Reis, G | 1 |
| Park, JB; Skalska, S; Son, S; Stern, JE | 1 |
| Hwang, JC; Lee, MC; Lin, JT; Tung, LC | 1 |
| Andreev, AA; Kalinina, MV; Karpova, MN; Klishina, NY; Kuznetsova, LV; Rebrov, IG | 1 |
| Daly, KC; Ghatak, C; Mwilaria, EK | 1 |
| Kupenova, P; Popova, E; Vitanova, L | 2 |
| Goodchild, AK; Hildreth, CM; Pilowsky, PM; van Deurzen, BT | 1 |
| Choi, SY; Choi, UK; Kang, JH; Kang, TC; Kim, DW; Kim, HT; Kim, JE; Kwak, SE; Kwon, OS; Lee, SJ | 1 |
| de Lima, AD; Klueva, J; Meis, S; Munsch, T; Voigt, T | 1 |
| Abdul, M; Hoosein, NM; Mccray, SD | 1 |
| Côrtes, WS; Lapa, MA; Mecawi, AS; Polo, PA; Reis, LC | 1 |
| Brinton, RD; Wang, JM | 1 |
| Hopp, FA; Mustapic, S; Sanchez, A; Stucke, AG; Stuth, EA; Zuperku, EJ | 1 |
| Good, CH; Lupica, CR | 1 |
| Amabeoku, G | 1 |
| Beenhakker, MP; Huguenard, JR; Kleiman-Weiner, M; Segal, WA | 1 |
| Bosma, MM; Kirkman, JL; Rockhill, W | 1 |
| Cepeda, C; Joshi, PR; Levine, MS; Masliah, E; Wu, N | 1 |
| Bear, CE; Bennett, SA; Cortez, MA; D'Antonio, C; Dhani, SU; Huan, LJ; Li, C; Snead, OC; Whitehead, SN | 1 |
| Denter, DG; Heck, N; Kilb, W; Luhmann, HJ; Riedemann, T; White, R | 1 |
| Aguilar, J; Bautista, W; Delgado-Lezama, R; Loeza-Alcocer, JE | 1 |
| Kosterin, P; Obaid, AL; Salzberg, BM | 1 |
| Jiang, S; Jiang, Z; Miao, B; Song, X | 1 |
| Chen, LB; Chen, X; Hong, C; Li, JC; Wang, F; Zou, D | 1 |
| Beech, JS; Corletto, F; Grainger, DJ; Grant, AJ; Lapaque, N; Loke, JC; Lummis, SC; Mastroeni, P; Menon, DK; Miller, NG; O'Brien, JA; Padgett, CL; Reckless, J; Thompson, AJ; Trowsdale, J; Wheeler, DW | 1 |
| Bian, W; Dave, V; Li, J; Ye, JH | 1 |
| Gao, JX; Jiang, YX; Yan, L; Yang, G; Yi, ZH | 1 |
| Puente, MA; Ritta, MN; Tartaglione, CM | 1 |
| Carlisle, HJ; Gunapala, KM; Indersmitten, T; Kennedy, MB; Khorosheva, E; Luong, TN; Medina-Marino, A; O'Dell, TJ; Patterson, PH; Schenker, L; Steele, AD | 1 |
| Baptista-Hon, DT; Deeb, TZ; Gallacher, M; Hales, TG; Othman, NA; Perry, DC | 1 |
| Dretchen, KL; Gillis, RA; Herman, MA; Sahibzada, N; Vicini, S | 1 |
| Gao, J; Jia, Y; Jiang, Y; Yan, L; Yang, G; Yu, J | 1 |
| Arnold, LA; Chen, Q; Cook, JM; Emala, CW; Ionescu-Zanetti, C; Johnson, J; Smith, S; Wang, ZJ; Yim, PD; Yuan, N | 1 |
| Barreto, E; Gluckman, BJ; Huang, XY; Schiff, SJ; Van Wert, S; Wu, JY; Xiao, Y | 1 |
| Cao, Z; Hammock, BD; Lein, PJ; McCoy, M; Pessah, IN; Rogawski, MA | 1 |
| Glover, JC; Kasumacic, N; Perreault, MC | 1 |
| Chesnoy-Marchais, D | 1 |
| Carbó Tano, M; Hermitte, G; Yang, M | 1 |
| Badanich, KA; Beckley, JT; Mulholland, PJ; Trantham-Davidson, H; Woodward, JJ | 1 |
| Anton, S; Chaffiol, A; Gu, Y; Lucas, P; Martinez, D; Rospars, JP; Voges, N | 1 |
| Marino, V; Parker, DA | 1 |
| Bukanova, JV; Sharonova, IN; Skrebitsky, VG | 1 |
| MacIver, MB | 1 |
| Kubová, H; Mareš, P | 1 |
| Feuerstein, TJ; Heida, T; Hofmann, UG; Moser, A; Stegenga, J; Tronnier, V; Xie, Y; Zhao, Y | 1 |
| Fleck, MW; Hoerbelt, P; Lindsley, TA | 1 |
| Allio, A; Calorio, C; Carbone, E; Franchino, C; Gavello, D; Marcantoni, A | 1 |
| Jones, RS; Lench, AM; Robson, E | 1 |
| Bhattarai, JP; Cho, DH; Chun, SW; Han, SK; Park, SJ | 1 |
| Aversa, D; Berretta, N; Biamonte, F; Cordella, A; D'Amelio, M; Federici, M; Guatteo, E; Landrock, KK; Latini, L; Ledonne, A; Martini, A; Mercuri, NB; Nobili, A; Rizzo, FR; Schepisi, C; Viscomi, MT | 1 |
| Toyoda, H | 1 |
| Aricescu, AR; Desai, R; Karia, D; Kotecha, A; Laverty, D; Malinauskas, T; Masiulis, S; Miller, KW; Pardon, E; Serna Martin, I; Steyaert, J; Uchański, T; Zivanov, J | 1 |
| Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y | 1 |
| Ahn, Y; Cho, HJ; Jo, K; Kwak, WK; Min, B; Suh, HJ | 1 |
| Cowgill, J; Fan, C; Haloi, N; Howard, RJ; Lindahl, E; Tobiasson, V; Zhuang, Y | 1 |
12 review(s) available for picrotoxin and bicuculline
| Article | Year |
|---|---|
GABA and central monoamine release.
Topics: Adrenal Glands; Aminooxyacetic Acid; Animals; Bicuculline; Biogenic Amines; Calcium; Cats; Central Nervous System; Chromaffin System; Corpus Striatum; Dogs; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Hypothalamus; Magnesium; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Serotonin; Synaptic Transmission; Thalamus | 1978 |
GABA-receptors in the vertebrate nervous system.
Topics: Action Potentials; Aging; Aminobutyrates; Animals; Bicuculline; Brain; Cats; Cerebellar Cortex; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Mice; Neural Inhibition; Picrotoxin; Rats; Receptors, Neurotransmitter; Social Isolation; Sodium; Spinal Cord; Structure-Activity Relationship | 1977 |
The pharmacology of the amphibian spinal cord.
Topics: Acetylcholine; Amino Acids; Anesthetics; Animals; Anura; Barbiturates; Bicuculline; Biogenic Amines; Bufonidae; Calcium; Hypnotics and Sedatives; Magnesium; Picrotoxin; Potassium; Rana catesbeiana; Ranidae; Sodium; Spinal Cord; Strychnine; Xenopus | 1978 |
Behavioural consequences of manipulating GABA neurotransmission in the superior colliculus.
Topics: Animals; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Motor Activity; Muscimol; Neurons, Afferent; Neurons, Efferent; Picrotoxin; Rats; Superior Colliculi; Synaptic Transmission | 1992 |
Kinetic properties and regulation of GABAA receptor channels.
Topics: Animals; Barbiturates; Benzodiazepines; Bicuculline; Carbolines; Ion Channel Gating; Ion Channels; Kinetics; Muscimol; Penicillins; Picrotoxin; Receptors, GABA-A; Steroids | 1992 |
GABA in morphine analgesia and tolerance.
Topics: Analgesia; Animals; Baclofen; Benzodiazepines; Bicuculline; Brain Chemistry; Cyclohexanecarboxylic Acids; Drug Tolerance; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Morphine; Muscimol; Naloxone; Picrotoxin; Rats; Receptors, GABA-A; Synaptic Transmission | 1985 |
Classification of inhibitory amino acid receptors in the mammalian nervous system.
Topics: Animals; Barbiturates; Bicuculline; Flurazepam; Humans; Muscimol; Nervous System; Picrotoxin; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Taurine | 1986 |
[2 types of effects of convulsants on the embryonic CNS].
Topics: Animals; Bicuculline; Central Nervous System; Chick Embryo; Convulsants; Methionine Sulfoximine; Movement; Oxotremorine; Penicillins; Pentylenetetrazole; Picrotoxin; Strychnine; Tetanus Toxin | 1985 |
The GABA postsynaptic membrane receptor-ionophore complex. Site of action of convulsant and anticonvulsant drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Bicuculline; Brain; Chlorides; Convulsants; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Picrotoxin; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Seizures; Synaptic Membranes | 1981 |
GABA receptor multiplicity. Visualization of different receptor types in the mammalian CNS.
Topics: Animals; Autoradiography; Bicuculline; Brain; Central Nervous System; Humans; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Synapses | 1984 |
Processing of information from different sources: spatial synaptic integration in the dendrites of vertebrate CNS neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium; Central Nervous System; Dendrites; Models, Neurological; Neurons; Picrotoxin; Purkinje Cells; Pyramidal Cells; Quinoxalines; Synaptic Transmission; Vertebrates | 1994 |
Physiological and pharmacological studies on annelid and nematode body wall muscle.
Topics: Amino Acid Sequence; Animals; Annelida; Bicuculline; Bungarotoxins; Molecular Sequence Data; Mollusk Venoms; Muscles; Nematoda; Neurotransmitter Agents; Picrotoxin | 1993 |
869 other study(ies) available for picrotoxin and bicuculline
| Article | Year |
|---|---|
5-HT antagonists in rat hippocampus.
Topics: Acetylcholine; Animals; Bicuculline; Cinanserin; Cyproheptadine; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Lysergic Acid Diethylamide; Male; Methiothepin; Methysergide; Mianserin; Norepinephrine; Picrotoxin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical | 1976 |
Effects of two benzodiazepines, phenobarbitone, and baclofen on synaptic transmission in the cat cuneate nucleus.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Baclofen; Bicuculline; Cats; Diazepam; Drug Interactions; Evoked Potentials; Flunitrazepam; Glutamate Decarboxylase; Medulla Oblongata; Neural Inhibition; Phenobarbital; Picrotoxin; Propionates; Semicarbazides; Synapses; Synaptic Transmission | 1976 |
The actions of picrotoxin, strychnine, bicuculline and other convulsants and antagonists on the responses to acetylcholine glutamic acid and gamma-aminobutyric acid on Helix neurones.
Topics: Acetylcholine; Aminobutyrates; Animals; Anticonvulsants; Bicuculline; Brain; Convulsants; gamma-Aminobutyric Acid; Glutamates; Helix, Snails; Isoquinolines; Neurons; Picrotoxin; Strychnine | 1977 |
Benzodiazepines and phenobarbital as antagonists of dissimilar chemical convulsants.
Topics: 3-Mercaptopropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Chlordiazepoxide; Convulsants; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Picrotoxin; Therapeutic Equivalency | 1978 |
Picrotoxin- and bicuculline-sensitive inhibition of cardiac vagal reflexes.
Topics: Afferent Pathways; Animals; Bicuculline; Brain Stem; Cats; Central Nervous System Stimulants; Decerebrate State; Electric Stimulation; Heart; Heart Rate; Hypothalamus; Isoquinolines; Neural Inhibition; Picrotoxin; Reflex; Spinal Cord; Vagus Nerve | 1979 |
Primitive nervous systems: action of aminergic drugs and blocking agents on activity in the ventral nerve cord of the flatworm Notoplana acticola.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Neurons; Neurotransmitter Agents; Pentylenetetrazole; Peripheral Nerves; Picrotoxin; Platyhelminths | 1979 |
Effects of systemically applied GABA agonists and antagonists on wave-spike ECoG activity in rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Electroencephalography; Epilepsy, Absence; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Male; Muscimol; Photic Stimulation; Picrotoxin; Rats; Strychnine | 1979 |
Neuronal and glial systems for gamma-aminobutyric acid transport.
Topics: Amino Acids, Diamino; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Biological Transport, Active; Calcium; Chlorpromazine; Cyclic AMP; gamma-Aminobutyric Acid; In Vitro Techniques; Neuroglia; Neurons; Picrotoxin; Potassium; Rabbits; Sodium; Strychnine; Synaptosomes; Tritium | 1975 |
Studies on convulsants in the isolated frog spinal cord. II. Effects on root potentials.
Topics: Action Potentials; Alanine; Animals; Bicuculline; Convulsants; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons, Afferent; Perfusion; Picrotoxin; Rana pipiens; Spinal Nerve Roots; Strychnine; Synapses; Synaptic Transmission; Taurine | 1975 |
Modification of involuntary movements by centrally acting drugs.
Topics: Aminooxyacetic Acid; Animals; Atropine; Bicuculline; Bromocriptine; Dopamine; Haloperidol; Haplorhini; Levodopa; Movement Disorders; Physostigmine; Picrotoxin; Piperazines; Piribedil; Receptors, Drug; Synaptic Transmission; Thalamic Nuclei; Theophylline | 1975 |
GABA receptor binding in frog spinal cord and brain.
Topics: Aminobutyrates; Animals; Anura; Bicuculline; Binding Sites; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Kinetics; Picrotoxin; Rana catesbeiana; Receptors, Cell Surface; Spinal Cord | 1977 |
Effect of elevated brain GABA concentrations on the actions of bicuculline and picrotoxin in mice.
Topics: Aminobutyrates; Animals; Bicuculline; Brain; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoquinolines; Male; Mice; Picrotoxin; Synaptic Transmission | 1977 |
A comparison of the inhibitory effects of taurine and GABA on identified Purkinje cells and other neurons in the cerebellar cortex of the rat.
Topics: Aminobutyrates; Animals; Bicuculline; Cerebellar Cortex; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Male; Neural Conduction; Neural Inhibition; Neurons; Picrotoxin; Purkinje Cells; Rats; Receptors, Neurotransmitter; Strychnine; Taurine | 1978 |
Feedback synaptic interaction in the dragonfly ocellar retina.
Topics: Animals; Bicuculline; Cockroaches; Feedback; gamma-Aminobutyric Acid; Insecta; Membrane Potentials; Models, Neurological; Neurons; Ocular Physiological Phenomena; Picrotoxin; Synapses; Synaptic Transmission; Tubocurarine; Vision, Ocular | 1978 |
Is GABA release modulated by presynaptic receptors?
Topics: Aminobutyrates; Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Oxazoles; Picrotoxin; Potassium; Rats; Receptors, Neurotransmitter; Taurine | 1978 |
Electrophysiological and pharmacological studies of the inhibitory projection from the cerebellar cortex to the deep cerebellar nuclei in tissue culture.
Topics: Animals; Bicuculline; Cerebellar Cortex; Cerebellar Nuclei; Culture Techniques; gamma-Aminobutyric Acid; Glycine; Mice; Neural Inhibition; Neural Pathways; Picrotoxin; Strychnine; Synaptic Transmission | 1978 |
GABA or potassium: which mediates primary afferent depolarization?
Topics: Afferent Pathways; Animals; Anura; Bicuculline; gamma-Aminobutyric Acid; Neurons, Afferent; Picrotoxin; Potassium; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission | 1979 |
Facilitation by GABA of the potassium-evoked release of 3-H-noradrenaline from the rat occipital cortex.
Topics: Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Muscimol; Nictitating Membrane; Norepinephrine; Picrotoxin; Potassium; Rats; Stimulation, Chemical; Synaptic Transmission; Tyramine | 1979 |
Delta-aminolaevulinic acid is a potent agonist for GABA autoreceptors.
Topics: Aminolevulinic Acid; Animals; Bicuculline; gamma-Aminobutyric Acid; Levulinic Acids; Male; Picrotoxin; Porphyrias; Potassium; Rats; Receptors, Neurotransmitter; Synaptosomes | 1979 |
Anticonvulsant activity of muscimol against seizures induced by impairment of GABA-mediated neurotransmission.
Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Strychnine; Synaptic Transmission | 1979 |
Effect of diazepam on cerebral 5-hydroxytryptamine synthesis.
Topics: 5-Hydroxytryptophan; Aminooxyacetic Acid; Animals; Bicuculline; Brain; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Reserpine; Serotonin | 1979 |
On the mechanism of vestibular disturbances caused by industrial solvents.
Topics: 1-Propanol; Animals; Barbiturates; Bicuculline; Chloralose; Electronystagmography; Ethanol; Eye Movements; Methanol; Occupational Medicine; Picrotoxin; Rabbits; Solvents; Styrenes; Trichloroethanes; Trichloroethylene; Vestibule, Labyrinth; Xylenes | 1979 |
Effects of alterations in the metabolism of gamma-aminobutyrate on convulsant potencies.
Topics: 3-Mercaptopropionic Acid; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Diacetyl; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Hydrazines; Male; Mice; Pentylenetetrazole; Phenelzine; Picrotoxin; Pyridoxine; Reaction Time; Seizures; Thiones; Valproic Acid | 1977 |
Facilitation of bicuculline- and picrotoxin-induced seizures by sodium valproate in rats.
Topics: Animals; Bicuculline; Drug Synergism; Male; Picrotoxin; Rats; Seizures; Valproic Acid | 1979 |
Involvement of central GABA-ergic systems in convulsions and aggressive behavior.
Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Bicuculline; Brain; Fatty Acids; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Muscimol; Picrotoxin; Rats; Seizures; Structure-Activity Relationship; Valproic Acid | 1979 |
Neuroactive properties of phosphonic amino acids.
Topics: Amino Acids; Animals; Bicuculline; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Phosphorylation; Picrotoxin; Rats | 1979 |
Enhancement of the binding of 3H-diazepam to rat brain membranes in vitro by SQ 20009, A novel anxiolytic, gamma-aminobutyric acid (GABA) and muscimol.
Topics: Animals; Bicuculline; Brain; Diazepam; Etazolate; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Muscimol; Nicotinic Acids; Oxazoles; Picrotoxin; Rats; Stimulation, Chemical | 1979 |
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines.
Topics: Animals; Benzodiazepines; Bicuculline; Cats; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Pentobarbital; Picrotoxin | 1979 |
Effect of diazepam on GABAergic cuneate neurons.
Topics: Animals; Bicuculline; Cats; Diazepam; gamma-Aminobutyric Acid; Glutamates; Medulla Oblongata; Neurons; Picrotoxin | 1979 |
Dual gamma-aminobutyric acid control of prolactin secretion in the rat.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Methyltyrosines; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats | 1979 |
GABA modulates the release of dopamine and acetylcholine from rat caudate nucleus slices.
Topics: Acetylcholine; Animals; Bicuculline; Caudate Nucleus; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Norepinephrine; Picrotoxin; Potassium; Rats; Tyrosine | 1979 |
The effect of strychnine, bicuculline, and picrotoxin on X and Y cells in the cat retina.
Topics: Action Potentials; Animals; Bicuculline; Cats; Light; Picrotoxin; Retina; Strychnine | 1979 |
Conductance changes during bath application of beta-alanine and taurine in giant interneurons of the isolated lamprey spinal cord.
Topics: Alanine; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Electrolytes; gamma-Aminobutyric Acid; Glycine; Interneurons; Lampreys; Membrane Potentials; Picrotoxin; Spinal Cord; Strychnine; Taurine | 1979 |
Influence of bicuculline and picrotoxin on reversal properties of excitatory synaptic potentials in cerebellar Purkinje cells of the rat.
Topics: Animals; Bicuculline; Cerebellum; Electric Stimulation; Evoked Potentials; Picrotoxin; Purkinje Cells; Rats; Synapses | 1979 |
Reduction of gamma-aminobutyric acid (GABA)-mediated transmission by a convulsant benzodiazepine.
Topics: Animals; Benzodiazepinones; Bicuculline; Cats; Convulsants; Female; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pentylenetetrazole; Picrotoxin; Reflex; Spinal Cord; Strychnine | 1979 |
The GABA dose/conductance relationship on lobster muscle.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Guanidines; In Vitro Techniques; Muscles; Nephropidae; Picrotoxin; Piperazines; Propionates; Valerates | 1979 |
Rotational behaviour after unilateral intranigral injection of muscimol in rats.
Topics: Aminobutyrates; Animals; Basidiomycota; Behavior; Bicuculline; gamma-Aminobutyric Acid; Humans; Injections; Isoxazoles; Male; Oxazoles; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra; Time Factors | 1977 |
Specific antagonism of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of convulsant action.
Topics: Amino Acids; Aminobutyrates; Animals; Bicuculline; Convulsants; Culture Techniques; gamma-Aminobutyric Acid; Iontophoresis; Mice; Neural Inhibition; Neurons; Penicillins; Pentylenetetrazole; Picrotoxin; Spinal Cord | 1978 |
Evidence that nigral GABA mediates behavioural responses elicited by striatal dopamine receptor stimulation.
Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; Catatonia; Corpus Striatum; Drug Interactions; gamma-Aminobutyric Acid; Humans; Hydroxydopamines; Injections; Male; Picrotoxin; Rats; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra | 1978 |
Substantia nigra as an out-put station for striatal dopaminergic responses: role of a GABA-mediated inhibition of pars reticulata neurons.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Hydroxydopamines; Kainic Acid; Male; Neurons; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra | 1979 |
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Humans; Isoxazoles; Male; Methyltyrosines; Morphine; Motor Activity; Muscimol; Picrotoxin; Rats; Reserpine | 1979 |
Comparison of effects of bicuculline, strychnine, and picrotoxin with those of pentylenetetrazol on photically evoked afterdischarges.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Electroencephalography; Isoquinolines; Light; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Strychnine; Visual Cortex | 1977 |
Effect of four convulsants on the time course of presynaptic inhibition and the relation to seizure activity.
Topics: Animals; Bemegride; Bicuculline; Cerebral Cortex; Convulsants; Instinct; Male; Medulla Oblongata; Neural Inhibition; Pentylenetetrazole; Picrotoxin; Rats; Seizures | 1977 |
Presynaptic modulating effects of GABA on depression, facilitation, and posttetanic potentiation of a cholinergic synapse in Aplysia californica.
Topics: Acetylcholine; Aminobutyrates; Animals; Aplysia; Azides; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Lithium; Membrane Potentials; Picrotoxin; Potassium; Sodium; Synapses | 1977 |
Effects of strychnine, bicuculline, and picrotoxin on inhibition of hypoglossal motoneurons.
Topics: Animals; Bicuculline; Cats; Evoked Potentials; Female; Hypoglossal Nerve; Isoquinolines; Lingual Nerve; Male; Motor Neurons; Neural Inhibition; Neurons, Afferent; Picrotoxin; Strychnine | 1977 |
Vasopressin release produced in anaesthetized cats by antagonists of gamma-aminobutyric acid and glycine.
Topics: Aminobutyrates; Anesthesia; Animals; Bicuculline; Blood Pressure; Cats; GABA Antagonists; Glycine; Medulla Oblongata; Pentylenetetrazole; Picrotoxin; Strychnine; Time Factors; Tubocurarine; Vasopressins | 1978 |
The effects of amino acids and antagonists on the isolated hemisected spinal cord of the immature rat.
Topics: Action Potentials; Amino Acids; Animals; Animals, Newborn; Bicuculline; In Vitro Techniques; Motor Neurons; Neurons, Afferent; Picrotoxin; Rats; Spinal Cord; Spinal Nerve Roots; Strychnine | 1978 |
Effects of drugs on gamma-aminobutyric acid receptors, uptake, release and synthesis in vitro.
Topics: Aminobutyrates; Animals; Astacoidea; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Imipramine; In Vitro Techniques; Male; Mice; Penicillin G; Pentylenetetrazole; Picrotoxin; Receptors, Drug; Synaptosomes | 1978 |
Electroencephalogram and somatosensory evoked potential changes after administration of six convulsant drugs.
Topics: Animals; Bemegride; Bicuculline; Cats; Convulsants; Electroencephalography; Evoked Potentials; Glycine; Pentylenetetrazole; Picrotoxin; Somatosensory Cortex; Strychnine; Time Factors | 1978 |
[Effect of blockers of pre- and post-synaptic inhibition on processes of habituation in the system of cutaneous sensitivity].
Topics: Adaptation, Physiological; Animals; Bicuculline; Cats; Isoquinolines; Neural Inhibition; Picrotoxin; Sensation; Skin; Spinal Cord; Strychnine; Synapses | 1978 |
Characterization and ionic basis of GABA-induced depolarizations recorded in vitro from cat primary afferent neurones.
Topics: Aminobutyrates; Animals; Anions; Bicuculline; Cats; Cell Membrane Permeability; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons, Afferent; Picrotoxin; Receptors, Drug | 1978 |
Supraspinal regulation of spinal reflex discharge into cardiac sympathetic nerves.
Topics: Animals; Bicuculline; Cats; Electric Stimulation; Heart Conduction System; Intercostal Nerves; Neurons, Afferent; Picrotoxin; Reaction Time; Reflex; Spinal Cord; Strychnine; Sympathetic Nervous System | 1978 |
The "mixed" effect of picrotoxin on the GABA dose/conductance relation recorded from lobster muscle.
Topics: Aminobutyrates; Animals; Bicuculline; Binding, Competitive; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Models, Biological; Nephropidae; Neural Conduction; Picrotoxin | 1978 |
A comparison of similar ionic responses to gamma-aminobutyric acid and acetylcholine.
Topics: Acetylcholine; Aminobutyrates; Animals; Aplysia; Bicuculline; Bungarotoxins; Cell Membrane Permeability; Chlorides; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Neurons; Picrotoxin; Potassium; Receptors, Drug; Sodium; Strychnine; Time Factors | 1978 |
Conductance increases produced by glycine and gamma-aminobutyric acid in lamprey interneurones.
Topics: Action Potentials; Aminobutyrates; Animals; Bicuculline; Chlorides; Electric Conductivity; Fishes; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Interneurons; Lampreys; Picrotoxin; Spinal Cord; Strychnine | 1978 |
Response of dopamine neurons in substantia nigra to muscimol.
Topics: Animals; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1978 |
Di-n-propylacetic acid--profile of anticonvulsant activity in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Ethosuximide; Female; Male; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Seizures; Strychnine; Trimethadione; Valerates; Valproic Acid | 1976 |
Na+-independent binding of GABA to the triton X-100 treated synaptic membranes from cerebellum of rat brain.
Topics: Aminobutyrates; Animals; Bicuculline; Binding Sites; Cerebellum; gamma-Aminobutyric Acid; Imidazoles; Kinetics; Male; Picrotoxin; Polyethylene Glycols; Rats; Sodium; Synaptic Membranes; Tubocurarine | 1977 |
Effect of GABA, picrotoxin and bicuculline on loss of noradrenaline and serotonin from rat brain mesodiencephalic region in vitro.
Topics: Aminobutyrates; Animals; Bicuculline; Brain; Diencephalon; Female; gamma-Aminobutyric Acid; Isoquinolines; Male; Mesencephalon; Norepinephrine; Picrotoxin; Rats; Receptors, Drug; Serotonin | 1977 |
Evidence for an intrastriatal GABA-ergic influence on dopamine neurones of the cat.
Topics: Acetylcholinesterase; Aminobutyrates; Animals; Bicuculline; Brain; Cats; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Male; Picrotoxin; Receptors, Dopamine | 1977 |
Evidence that GABA is not the afferent transmitter in the cochlea.
Topics: Acoustic Stimulation; Action Potentials; Aminobutyrates; Animals; Bicuculline; Cats; Cerebral Ventricles; Cochlea; Cochlear Nerve; Electric Stimulation; GABA Antagonists; Neurons, Afferent; Neurons, Efferent; Picrotoxin; Synapses | 1977 |
Comparison of bicyclic phosphorous esters with bicuculline and picrotoxin as antagonists of presynaptic inhibition in the rat cuneate nucleus.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Isoquinolines; Medulla Oblongata; Organophosphorus Compounds; Picrotoxin; Rats; Synapses | 1977 |
Amacrine cells in Necturus retina: evidence for independent gamma-aminobutyric acid- and glycine-releasing neurons.
Topics: Aminobutyrates; Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia; Glycine; In Vitro Techniques; Neural Inhibition; Neurons; Photic Stimulation; Picrotoxin; Retina; Strychnine; Urodela | 1977 |
The effects of drugs on the field potential in the caudate nucleus following nigra stimulation.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Cats; Caudate Nucleus; Evoked Potentials; Haloperidol; Neural Conduction; Neural Inhibition; Picrotoxin; Reserpine; Substantia Nigra | 1977 |
The role of GABA in dyskinesias induced by chemical stimulation of the striatum.
Topics: Aminobutyrates; Animals; Bicuculline; Corpus Striatum; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats | 1977 |
Effects of GABA, glycine, picrotoxin and bicuculline methochloride on rubrospinal neurones in cats.
Topics: Aminobutyrates; Animals; Bicuculline; Cats; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Neural Inhibition; Neural Pathways; Picrotoxin; Red Nucleus; Spinal Cord; Synaptic Membranes | 1976 |
Action of amino acids and convulsants on cerebellar spontaneous action potentials in vitro: effects of deprivation of C1-, K+ of Na+.
Topics: Action Potentials; Alanine; Amino Acids; Animals; Bicuculline; Cerebellum; Chlorides; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; Iodides; Isethionic Acid; Nitrates; Picrotoxin; Potassium; Sodium; Strychnine; Sulfates | 1976 |
Inhibitory effects of acetylcholine on neurones in the feline nucleus reticularis thalami.
Topics: Acetylcholine; Action Potentials; Animals; Bicuculline; Cats; Depression, Chemical; Female; gamma-Aminobutyric Acid; Glycine; Male; Neurons; Picrotoxin; Receptors, Cholinergic; Strychnine; Thalamic Nuclei | 1976 |
Changes in regional brain acetylcholine levels during drug-induced convulsions.
Topics: Acetylcholine; Animals; Bicuculline; Brain Chemistry; Male; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Strychnine | 1976 |
The involvement of gamma-aminobutyric acid in the organization of cat retinal ganglion cell receptive fields. A study with picrotoxin and bicuculline.
Topics: Adaptation, Physiological; Aminobutyrates; Animals; Bicuculline; Cats; GABA Antagonists; Ganglia; Isoquinolines; Picrotoxin; Retina | 1976 |
A neuropharmacological comparison of the convulsant activity of several putative GABA antagonists.
Topics: Aminobutyrates; Animals; Bicuculline; Convulsants; Electroencephalography; GABA Antagonists; Male; Penicillin G; Picrotoxin; Rats; Time Factors | 1976 |
Electrophysiological studies of fetal mouse olifactory bulb explants during development of synaptic functions in culture.
Topics: Action Potentials; Animals; Bicuculline; Caffeine; Evoked Potentials; Fetus; gamma-Aminobutyric Acid; Mice; Neural Inhibition; Neurons; Olfactory Bulb; Organ Culture Techniques; Picrotoxin; Synapses; Time Factors; Tubocurarine | 1976 |
Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses.
Topics: Alanine; Amino Acids; Aminocaproates; Aminoisobutyric Acids; Animals; Asparagine; Bicuculline; Convulsants; Cystathionine; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Imidazoles; In Vitro Techniques; Isomerism; Leucine; Membrane Potentials; Nerve Endings; Neurons, Afferent; Picrotoxin; Rana pipiens; Serine; Spinal Cord; Strychnine; Taurine; Threonine; Valine | 1975 |
The effects of various amino acids, dopamine and some convulsants on the electroretinogram of the rabbit.
Topics: Alanine; Amino Acids; Animals; Bicuculline; Convulsants; Dopamine; Electroretinography; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Male; Picrotoxin; Rabbits; Retina; Strychnine; Taurine | 1975 |
The effect of intravenously administered gamma-aminobutyric acid on afferent fiber polarization.
Topics: Aminobutyrates; Animals; Bicuculline; Cats; Decerebrate State; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Injections, Intra-Arterial; Injections, Intravenous; Lumbar Vertebrae; Membrane Potentials; Neurons; Neurons, Afferent; Phenoxybenzamine; Picrotoxin; Tetrodotoxin | 1975 |
Pentobarbital: action on frog motoneurons.
Topics: Animals; Anura; Aspartic Acid; Bicuculline; Cell Membrane Permeability; Depression, Chemical; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Motor Neurons; Pentobarbital; Picrotoxin | 1975 |
Binding of gamma-aminobutyric acid to crayfish muscle and its relationship to receptor sites.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Astacoidea; Bicuculline; Binding Sites; Chlorpromazine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Mercaptoethanol; Muscle Proteins; Muscles; Picrotoxin; Protein Binding | 1975 |
Comparison of bicuculline methochloride with bicuculline and picrotoxin as antagonists of amino acid and monoamine depression of neurones in the rat brainstem.
Topics: Amino Acids; Animals; Bicuculline; Biogenic Amines; Brain Stem; Depression, Chemical; Imidazoles; Isoquinolines; Neurons; Picrotoxin; Rats; Receptors, Drug; Time Factors | 1975 |
The effects of GABA, Picrotoxin and bicuculline on the spontaneous bioelectric activity of cultured cerebellar Purkinje cells.
Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Depression, Chemical; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Isoquinolines; Picrotoxin; Purkinje Cells; Rats; Stimulation, Chemical; Strychnine | 1975 |
The action of picrotoxin and bicuculline on rat caudate neurons inhibited by GABA.
Topics: Aminobutyrates; Animals; Bicuculline; Caudate Nucleus; Cerebral Cortex; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Isoquinolines; Male; Picrotoxin; Rats | 1976 |
Effects of GABA blockade on lateral hypothalamic self-stimulation.
Topics: Aminobutyrates; Animals; Bicuculline; gamma-Aminobutyric Acid; Hypothalamus; Male; Picrotoxin; Rats; Self Stimulation | 1976 |
Interleukin-2 inhibits the GABA-induced Cl- current in identified Aplysia neurons.
Topics: Animals; Aplysia; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Interleukin-2; Ion Channels; Membranes; Muscimol; Neurons; Picrotoxin; Recombinant Proteins; Seawater | 1992 |
A highly selective kappa-opioid receptor agonist, CI-977, reduces excitatory synaptic potentials in the rat locus coeruleus in vitro.
Topics: Amino Acids; Analgesics; Animals; Benzofurans; Benzomorphans; Bicuculline; Depression, Chemical; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Ligands; Locus Coeruleus; Membrane Potentials; Naloxone; Naltrexone; Picrotoxin; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1992 |
Desensitization of GABAB receptors and antagonism by CGP 35348, prevent bicuculline- and picrotoxin-induced antinociception.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Tolerance; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Mice; Motor Activity; Organophosphorus Compounds; Pain Measurement; Pentobarbital; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
[Effects of GABA antagonist-induced seizures on 3H-muscimol and 3H-diazepam binding in the rat striatum].
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Diazepam; GABA Antagonists; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A; Seizures; Tritium | 1992 |
Pharmacological study of the chicken's monocular optokinetic nystagmus: effects of GABAergic agonist and antagonists.
Topics: Animals; Bicuculline; Chickens; Electroretinography; Eye Movements; Injections; Isoxazoles; Nystagmus, Optokinetic; Picrotoxin; Receptors, GABA-A; Retina; Vision, Monocular; Visual Pathways | 1992 |
The role of GABA receptors in the control of nigrostriatal dopaminergic neurons: dual-probe microdialysis study in awake rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acrylates; Animals; Baclofen; Bicuculline; Corpus Striatum; Dendrites; Dopamine; Male; Muscimol; Neurons; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Substantia Nigra | 1992 |
Inhibitory responses of rat basolateral amygdaloid neurons recorded in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amygdala; Animals; Baclofen; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Histocytochemistry; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Neurons; Picrotoxin; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereotyped Behavior | 1992 |
Involvement of central GABAA receptor complex in controlling the basal gastric secretory activity in pylorus-ligated rats.
Topics: Analysis of Variance; Anesthesia; Animals; Bicuculline; Diazepam; Gastric Acid; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
[A pharmacological analysis of the role of GABA- and opioidergic systems in the development of brain edema].
Topics: Animals; Bicuculline; Brain; Brain Edema; Female; Male; Mitochondria; Naloxone; Oxidative Phosphorylation; Picrotoxin; Rats; Receptors, GABA-A; Receptors, Opioid; Semicarbazides | 1992 |
[The effect of activation of the superior colliculus on the convulsive activity during picrotoxin-induced kindling].
Topics: Animals; Bicuculline; Electroencephalography; Kindling, Neurologic; Male; Microinjections; Penicillin G; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Seizures; Superior Colliculi | 1992 |
Participation of GABAergic systems in the production of antinociception by various stresses in mice.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Stress, Psychological | 1992 |
Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum.
Topics: Animals; Ascaris suum; Bicuculline; Cholinergic Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ivermectin; Muscles; Organophosphorus Compounds; Parasympatholytics; Parasympathomimetics; Picrotoxin; Receptors, Cholinergic; Receptors, GABA-A | 1992 |
Gamma-aminobutyric acid-glutamate interaction in the control of somatostatin release from hypothalamic neurons in primary culture: in vivo corroboration.
Topics: Animals; Bicuculline; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Fetus; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypothalamus; Kinetics; Male; Median Eminence; Neurons; Picrotoxin; Pipecolic Acids; Rats; Rats, Inbred Strains; Reference Values; Somatostatin; Tetrodotoxin | 1992 |
Receptor subtypes involved in callosally-induced postsynaptic potentials in rat frontal agranular cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Callosum; Electric Stimulation; Evoked Potentials; Frontal Lobe; GABA Antagonists; In Vitro Techniques; Male; Picrotoxin; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Synapses | 1992 |
Inhibitory effects of beta-alanine on the vagal efferent and afferent excitatory responses of the stomach to stimulation of vagal trunk in cats.
Topics: Animals; beta-Alanine; Bicuculline; Cats; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glycine; Hexamethonium; Hexamethonium Compounds; Male; Neurons, Afferent; Neurons, Efferent; Picrotoxin; Stomach; Taurine; Vagus Nerve | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Receptive field properties of rod-driven horizontal cells in the skate retina.
Topics: Animals; Bicuculline; Dopamine; gamma-Aminobutyric Acid; Glycine; Intercellular Junctions; Isoquinolines; Light; Neurotransmitter Agents; Photoreceptor Cells; Picrotoxin; Retina; Skates, Fish | 1992 |
Neurochemical mechanisms of memory control.
Topics: Amnesia; Animals; Bicuculline; Brain; Cats; Dopamine; Evoked Potentials; Flumazenil; GABA-A Receptor Antagonists; Male; Memory; Mice; Mice, Inbred BALB C; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Characterization of bicuculline/baclofen-insensitive gamma-aminobutyric acid receptors expressed in Xenopus oocytes. I. Effects of Cl- channel inhibitors.
Topics: Animals; Baclofen; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chloride Channels; Chlorides; Cloning, Molecular; Ion Channels; Membrane Proteins; Ovum; Picrotoxin; Rats; Receptors, GABA-A; Retina; RNA; Xenopus | 1992 |
Chloride current induced by alcohols in rat dorsal root ganglion neurons.
Topics: Alcohols; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Picrotoxin; Rats; Structure-Activity Relationship | 1992 |
In vitro effects of milbemycin oxime: mechanism of action against Angiostrongylus cantonensis and Dirofilaria immitis.
Topics: Angiostrongylus; Animals; Anthelmintics; Anti-Bacterial Agents; Bicuculline; Dibenzylchlorethamine; Dirofilaria immitis; Dogs; Female; Macrolides; Movement; Picrotoxin; Rats; Strychnine | 1992 |
[The threshold lowering effects of chronic treatment with haloperidol on beta-carboline derivative-induced tonic convulsion].
Topics: Animals; Bicuculline; Carbolines; Drug Administration Schedule; Drug Interactions; Haloperidol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Seizures | 1992 |
Neuropharmacology of amide derivatives of P-GABA.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Brain; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Muscle Relaxation; Nervous System; Picrotoxin; Seizures | 1992 |
Synaptic inhibition of accessory motoneurons evoked by stimulation of the trigeminal nerve in the cat.
Topics: Accessory Nerve; Animals; Bicuculline; Cats; Electric Stimulation; Motor Neurons; Neural Inhibition; Picrotoxin; Strychnine; Synapses; Trigeminal Nerve | 1992 |
GABAA and GABAB-receptor agonists evoked vagal nerve efferent transmission in the rat.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Efferent Pathways; Gastric Acid; Male; Muscimol; N-Methylscopolamine; Parasympatholytics; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Scopolamine; Scopolamine Derivatives; Synaptic Transmission; Vagus Nerve | 1991 |
GABAA and GABAB receptor-mediated effects on the spontaneous activity of the longitudinal layer in cat terminal ileum.
Topics: Animals; Baclofen; Bicuculline; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1991 |
Depolarizing actions of GABA and glycine on amphibian retinal horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Cobalt; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kynurenine; Lithium; Neuromuscular Depolarizing Agents; Nicotinic Acids; Picrotoxin; Receptors, GABA-A; Retina; Urodela | 1991 |
Can Cl- ions be extruded from a gamma-aminobutyric (GABA)-acceptive nerve cell via GABAA receptors on the plasma membrane cytoplasmic side?
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; Cytoplasm; gamma-Aminobutyric Acid; Membrane Potentials; Models, Biological; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A; Vestibular Nucleus, Lateral | 1991 |
Benzodiazepine receptor ligands and sexual behavior in the male rat: the role of GABAergic mechanisms.
Topics: Animals; Bicuculline; Carbolines; Chlordiazepoxide; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal | 1991 |
Altered response to GABAergic agents following electro and chemo convulsions in mice.
Topics: Animals; Bicuculline; Electroshock; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1991 |
Effects of GABA and related agents on the electrical activity of hypothalamic ventromedial nucleus neurons in vitro.
Topics: Animals; Baclofen; Bicuculline; Electrophysiology; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Ventromedial Hypothalamic Nucleus | 1991 |
Gestational exposure to diazepam increases sensitivity to convulsants that act at the GABA/benzodiazepine receptor complex.
Topics: Animals; Bicuculline; Caffeine; Carbolines; Cerebral Cortex; Chlorides; Convulsants; Diazepam; Female; GABA-A Receptor Antagonists; Male; Picrotoxin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, GABA-A; Seizures; Strychnine; Synaptosomes | 1991 |
Effects of GABA antagonists and habituation to novelty on ethanol-induced locomotor activity in mice.
Topics: Animals; Arousal; Bicuculline; Brain; Dose-Response Relationship, Drug; Ethanol; GABA Antagonists; Habituation, Psychophysiologic; Male; Mice; Motor Activity; Picrotoxin; Receptors, GABA-A; Social Environment | 1991 |
The effects of pentobarbital and benzodiazepines on GABA-responses in the periphery and spinal cord in vitro.
Topics: Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Male; Pentobarbital; Peripheral Nerves; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synapses; Vagus Nerve | 1991 |
GABAergic drugs and conflict behavior in the rat: lack of similarities with the actions of benzodiazepines.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Behavior, Animal; Benzodiazepines; Bicuculline; Brain; Conflict, Psychological; Drug Interactions; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Nicotinic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1991 |
Kinetic properties of two anatomically distinct excitatory synapses in hippocampal CA3 pyramidal neurons.
Topics: Animals; Bicuculline; Cesium; Dendrites; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1991 |
Modulation of GABA-mediated inhibition in rat cerebellar slices by benzodiazepine receptor ligands.
Topics: Animals; Bicuculline; Cerebellum; Electric Stimulation; Electrodes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Male; Picrotoxin; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
gamma-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex.
Topics: Amino Acids; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Culture Media; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Nerve Endings; Nipecotic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Somatostatin; Synaptosomes | 1991 |
Effects of anxiolytic drugs on escape behavior induced by dorsal central gray stimulation in rats.
Topics: Animals; Anti-Anxiety Agents; Arousal; Avoidance Learning; Bicuculline; Brain Mapping; Bromazepam; Chlordiazepoxide; Diazepam; Electric Stimulation; Escape Reaction; GABA Antagonists; Male; Meprobamate; Pentobarbital; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains; Sensory Thresholds | 1991 |
Dorsal root potentials in the isolated frog spinal cord: amino acid neurotransmitters and magnesium ions.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kynurenic Acid; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Potassium Channels; Quinoxalines; Rana pipiens; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots; Synaptic Transmission | 1991 |
Involvement of the GABAA/benzodiazepine chloride ionophore receptor complex in the 5,7-DHT Induced anticonflict effect.
Topics: 5,7-Dihydroxytryptamine; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Bicuculline; Diazepam; Drinking Behavior; Electroshock; Flumazenil; Hippocampus; Injections, Intraventricular; Limbic System; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1991 |
Synchronized GABAergic IPSPs recorded in the neocortex after blockade of synaptic transmission mediated by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Picrotoxin; Quinoxalines; Synapses; Synaptic Transmission | 1991 |
Interaction of hypothalamic GABAA and excitatory amino acid receptors controlling heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kynurenic Acid; Male; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
Hippocampal inputs to identified neurons in an in vitro slice preparation of the rat nucleus accumbens: evidence for feed-forward inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Cell Membrane; Electric Stimulation; Hippocampus; Male; Membrane Potentials; Neurons; Nucleus Accumbens; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Synapses | 1991 |
NMDA receptors participate differentially in two different synaptic inputs in neurons of the zebra finch robust nucleus of the archistriatum in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Birds; Brain; Electric Stimulation; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Picrotoxin; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Vocalization, Animal | 1991 |
Involvement of GABAergic systems in benzodiazepine-induced impairment of passive avoidance learning in mice.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; Chlordiazepoxide; Drug Interactions; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin | 1991 |
Effects of dihydroavermectin B1a and analogs on stretcher muscle of the lined shore crab, Pachygrapsus crassipes.
Topics: Animals; Anthelmintics; Bicuculline; Brachyura; Caenorhabditis; Chlorides; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Membrane Potentials; Membranes; Motor Endplate; Muscimol; Muscles; Picrotoxin; Sesterterpenes; Structure-Activity Relationship; Synapses; Time Factors | 1991 |
Action of taurine, 3-aminopropanesulfonic acid, and GABA on the hindgut and heart of the cockroach, Leucophaea maderae.
Topics: Amino Acids; Animals; Bicuculline; Cockroaches; Digestive System; Digestive System Physiological Phenomena; gamma-Aminobutyric Acid; Heart; In Vitro Techniques; Neurotransmitter Agents; Organ Specificity; Picrotoxin; Taurine | 1991 |
Secondary generalization in non-kindled rats following acute administration of GABA-complex and adenosine antagonists.
Topics: Adenosine; Aminophylline; Amygdala; Animals; Bicuculline; Carbolines; Cerebral Cortex; Disease Models, Animal; Electrodes, Implanted; Epilepsies, Partial; GABA Antagonists; Harmine; Kindling, Neurologic; Male; Picrotoxin; Rats | 1990 |
Effects of glycine and GABA on isolated bipolar cells of the mouse retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Mice; Neurons; Pentobarbital; Picrotoxin; Potassium; Retina; Sodium; Strychnine | 1990 |
GABAA receptor-mediated increase in membrane chloride conductance in rat paratracheal neurones.
Topics: Animals; Bicuculline; Cell Membrane; Chlorides; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin; Trachea | 1990 |
Pharmacological evidence indicating a role of GABAergic systems in termination of limbic seizures.
Topics: Animals; Baclofen; Bicuculline; Chloride Channels; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Limbic System; Male; Membrane Proteins; Muscimol; Neural Inhibition; Picrotoxin; Rats; Seizures | 1990 |
Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.
Topics: Animals; Baclofen; Bicuculline; Cattle; Cerebral Cortex; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression; Membrane Potentials; Oocytes; Pentobarbital; Picrotoxin; Poly A; Rats; Receptors, GABA-A; Retina; RNA; RNA, Messenger; Transfection; Xenopus | 1991 |
Volatile anesthetics gate a chloride current in postnatal rat hippocampal neurons.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anesthetics; Animals; Animals, Newborn; Bicuculline; Chlorine; Chromatography, Gas; Culture Techniques; Dose-Response Relationship, Drug; Electrophysiology; Enflurane; gamma-Aminobutyric Acid; Halothane; Hippocampus; Ion Channel Gating; Isoflurane; Neurons; Picrotoxin; Rats; Sesterterpenes; Strychnine | 1992 |
Evidence that genetic differences in habituation and GABAergic mechanisms may be related to sensitivity to ethanol and development of ethanol tolerance in mice.
Topics: Animals; Avoidance Learning; Bicuculline; Body Temperature; Brain; Drug Tolerance; Environment; Ethanol; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Motor Activity; Picrotoxin; Postural Balance; Seizures; Sleep; Species Specificity | 1991 |
Mechanical analysis of heterogenic inhibition between soleus muscle and the pretibial flexors in the cat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Bicuculline; Cats; Electric Stimulation; Electromyography; Female; Hindlimb; Injections, Intravenous; Isometric Contraction; Joints; Male; Muscles; Neural Pathways; Picrotoxin; Proprioception; Reflex; Strychnine | 1991 |
Effects of synaptic drugs on turtle optokinetic nystagmus and the spike responses of the basal optic nucleus.
Topics: Aminobutyrates; Animals; Bicuculline; Electronystagmography; Electrophysiology; Nystagmus, Physiologic; Oculomotor Nerve; Photic Stimulation; Picrotoxin; Retina; Turtles; Visual Pathways | 1991 |
[Effects of activation and lesions of the superior colliculi of the lamina quadrigemina on epileptic activity in rats].
Topics: Animals; Bicuculline; Electrophysiology; Epilepsy; Kindling, Neurologic; Male; Penicillins; Picrotoxin; Rats; Rats, Inbred Strains; Superior Colliculi | 1991 |
Changes in rat brain extracellular glutamate concentration during seizures induced by systemic picrotoxin or focal bicuculline injection: an in vivo dialysis study with on-line enzymatic detection.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicuculline; Brain Chemistry; Cerebral Cortex; Dialysis; Electroencephalography; Electroshock; Extracellular Space; Glutamates; Hippocampus; Injections; Kainic Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1991 |
Action of gamma-aminobutyric acid (GABA) in the isolated photosensory pineal organ.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Kinetics; Light; Muscimol; Neurons; Photic Stimulation; Picrotoxin; Pineal Gland; Time Factors; Trout | 1991 |
The cerebellopontine system: an electrophysiological study in the rat.
Topics: Animals; Bicuculline; Cerebellum; Electric Stimulation; Electrophysiology; Evoked Potentials; Male; Neurons; Picrotoxin; Pons; Rats; Rats, Inbred Strains | 1991 |
Effect of phenobarbital on motor seizures elicited by picrotoxin and bicuculline in rats.
Topics: Animals; Bicuculline; Male; Pentylenetetrazole; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1991 |
Decreased sensitivity of cerebellar nuclei neurons to GABA and taurine: effects of long-term inferior olive destruction in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Bicuculline; Cerebellar Nuclei; gamma-Aminobutyric Acid; Iontophoresis; Male; Neurons; Olivary Nucleus; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains; Reference Values; Strychnine; Taurine | 1991 |
Differential roles of the caudate nucleus and putamen in motor behavior of the cat as investigated by local injection of GABA antagonists.
Topics: Animals; Bicuculline; Cats; Caudate Nucleus; Diffusion; GABA Antagonists; Injections; Motor Activity; Movement; Picrotoxin; Putamen | 1991 |
Effects of gamma-aminobutyric acid and glycine on synaptic excitability of neurones in the solitary tract nucleus.
Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Medulla Oblongata; Neurons, Afferent; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Synapses | 1991 |
Effects of chlordiazepoxide and putative anxiogenics on conditioned suppression in rats.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Arousal; Avoidance Learning; Bicuculline; Chlordiazepoxide; Conditioning, Classical; Dose-Response Relationship, Drug; Electroshock; Fear; Flumazenil; Male; Picrotoxin; Rats; Rats, Inbred Strains | 1991 |
Posterior hypothalamic modulation of the respiratory response to CO2 in cats.
Topics: Animals; Bicuculline; Carbon Dioxide; Cats; GABA Antagonists; Hypothalamus, Posterior; Microinjections; Partial Pressure; Phrenic Nerve; Picrotoxin; Respiration | 1991 |
Interaction between pressor and depressor areas in cat ventrolateral medulla.
Topics: Animals; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Kainic Acid; Male; Medulla Oblongata; Models, Neurological; Organ Specificity; Picrotoxin; Strychnine; Time Factors | 1991 |
A comparative study of the effects of delta-aminolaevulinic acid and the GABAA agonist, muscimol, in rat jejunal preparations.
Topics: Aminolevulinic Acid; Animals; Bicuculline; Drug Synergism; In Vitro Techniques; Jejunum; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Rats; Rats, Inbred Strains | 1991 |
Synthesis and anticonvulsant activity of some benzopyranone imino derivatives of GABA and related compounds.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Chromans; gamma-Aminobutyric Acid; Imines; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Pentylenetetrazole; Picrotoxin; Rats | 1991 |
Hypothalamic GABAergic modulation of respiratory responses to baroreceptor stimulation.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbon Dioxide; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Microinjections; Picrotoxin; Pressoreceptors; Rats; Rats, Inbred Strains; Respiration | 1991 |
Inhibitory synaptic inputs to the respiratory rhythm generator in the medulla isolated from newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Respiration; Strychnine; Synapses | 1990 |
[The participation of the GABA-A and GABA-B receptors in the mechanism of the inhibition of the contractile activity in the rabbit myometrium under the influence of GABA, AOAA and fenibut].
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rabbits; Receptors, GABA-A; Uterine Contraction | 1990 |
Peripheral administration of picrotoxin and bicuculline stimulates in vivo somatostatin release from rat median eminence.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Median Eminence; Picrotoxin; Rats; Rats, Inbred Strains; Somatostatin | 1990 |
[Comparative evaluation of anticonvulsant and anti-arrhythmic effects of phenazepam, a benzodiazepine receptor agonist].
Topics: Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Bicuculline; Heart; Male; Mice; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Thiosemicarbazones | 1990 |
Posterior midbrain-induced locomotion.
Topics: Animals; Aspartic Acid; Bicuculline; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Mesencephalon; Muscles; N-Methylaspartate; Neurotransmitter Agents; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
GABA mediated inhibition of abdominal postural flexion in lobster.
Topics: Abdomen; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Interneurons; Muscimol; Nephropidae; Physical Stimulation; Picrotoxin; Posture; Reflex | 1991 |
gamma-Aminobutyric acid-induced response in acutely isolated nucleus solitarii neurons of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Penicillin G; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1991 |
Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA.
Topics: Analgesia; Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; N-Methylaspartate; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Receptors, Serotonin; Serotonin; Spinal Cord | 1991 |
Interactions of GABAA antagonists with deltamethrin, diazepam, pentobarbital, and SKF100330A in the rat dentate gyrus.
Topics: Action Potentials; Animals; Anticonvulsants; Bicuculline; Diazepam; Drug Interactions; Female; GABA Antagonists; Hippocampus; Insecticides; Male; Membrane Potentials; Nicotinic Acids; Nitriles; Pentobarbital; Picrotoxin; Pyrethrins; Rats; Rats, Inbred Strains | 1991 |
[Observation on phrenic discharges induced by bicuculline or picrotoxin in spinal rabbits].
Topics: Animals; Bicuculline; Evoked Potentials; Female; gamma-Aminobutyric Acid; Male; Phrenic Nerve; Picrotoxin; Rabbits; Respiration; Spinal Cord | 1990 |
Ketamine suppresses both bicuculline- and picrotoxin-induced generalized tonic-clonic seizures during ontogenesis.
Topics: Aging; Animals; Ataxia; Bicuculline; Ketamine; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1990 |
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Neurons; Pentylenetetrazole; Picrotoxin; Rats; Succinimides; Thalamus | 1990 |
Dual species dependent effect of dihydroergosine on the convulsions induced by GABA antagonists.
Topics: Animals; Antidepressive Agents; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Ergotamines; Female; Male; Mice; Mice, Inbred CBA; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Species Specificity | 1990 |
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Taurine; Tetrodotoxin | 1990 |
GABA receptors in the posterior hypothalamus regulate experimental anxiety in rats.
Topics: Animals; Anxiety; Bicuculline; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Synchronous discharges in the rat entorhinal cortex in vitro: site of initiation and the role of excitatory amino acid receptors.
Topics: Action Potentials; Animals; Bicuculline; Cats; Cerebral Cortex; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1990 |
Enhancement by GABA of the stimulation-evoked catecholamine release from cultured bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Glands; Animals; Bicuculline; Caffeine; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Nicotine; Picrotoxin; Potassium; Receptors, GABA-A; Veratridine | 1990 |
[The effect of glycine and gamma-aminobutyric acid on the excitatory postsynaptic potentials of the spinal motor neurons in the lamprey in the presence of antagonists].
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Fishes; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Lampreys; Membrane Potentials; Motor Neurons; Picrotoxin; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
Taurine interacts with GABAA and GABAB receptors in the brain.
Topics: Animals; Baclofen; Bicuculline; Brain; Chlorides; Female; GABA Antagonists; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Picrotoxin; Potassium; Receptors, GABA-A; Strychnine; Taurine | 1990 |
[The depressing effect of GABA on synaptic excitation in isolated rat hippocampal slices].
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Neurons; Penicillin G Benzathine; Picrotoxin; Rats; Receptors, Neurotransmitter; Synapses | 1990 |
Effects of gamma-aminobutyric acid on skate retinal horizontal cells: evidence for an electrogenic uptake mechanism.
Topics: Animals; Bicuculline; Biological Transport, Active; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Nipecotic Acids; Picrotoxin; Proline; Retina; Skates, Fish; Sodium | 1990 |
Anticonvulsant action of an arylamine-containing fraction from Agelenopsis spider venom.
Topics: Animals; Anticonvulsants; Bicuculline; Biogenic Amines; Chemical Fractionation; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Intraventricular; Kainic Acid; Male; Molecular Weight; Picrotoxin; Rats; Rats, Inbred Strains; Spider Venoms | 1990 |
Bicuculline and picrotoxin block phase advances induced by GABA agonists in the circadian rhythm of locomotor activity in the golden hamster by a phaclofen-insensitive mechanism.
Topics: Animals; Baclofen; Bicuculline; Circadian Rhythm; Cricetinae; gamma-Aminobutyric Acid; Male; Mesocricetus; Microinjections; Motor Activity; Muscimol; Picrotoxin; Stereotaxic Techniques; Triazolam | 1990 |
Stimulation of 36Cl- influx into rabbit cerebral cortex microsacs by the endogenous antigen S-100.
Topics: Animals; Bicuculline; Cerebral Cortex; Chlorides; Chlorine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Picrotoxin; Rabbits; Radioisotopes; S100 Proteins | 1990 |
Whole-cell patch study of GABAergic inhibition in CA1 neurons of immature rat hippocampal slices.
Topics: Animals; Animals, Newborn; Bicuculline; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Synthesis and anticonvulsant activity of some new 2-substituted 3-aryl-4(3H)-quinazolinones.
Topics: Animals; Anticonvulsants; Bicuculline; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Lethal Dose 50; Male; Methaqualone; Mice; Molecular Structure; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1990 |
Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Nervous System Diseases; Picrotoxin; Pyrrolidinones; Synaptic Membranes | 1990 |
[The action of bicuculline and picrotoxin on the fast and slow IPSPs of the pyramidal neurons in isolated slices of rat hippocampus].
Topics: Animals; Bicuculline; Dendrites; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; In Vitro Techniques; Membrane Potentials; Microelectrodes; Neural Inhibition; Neurons; Picrotoxin; Rats | 1990 |
Suppression of spontaneous generalized non-convulsive seizures in the rat by microinjection of GABA antagonists into the superior colliculus.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Superior Colliculi | 1990 |
Possible involvement of K+-conductance in the action of gamma-aminobutyric acid in the guinea-pig hippocampus.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Iontophoresis; Membrane Potentials; Neuromuscular Depolarizing Agents; Picrotoxin; Sodium | 1985 |
Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.
Topics: Animals; Bicuculline; Biological Transport; Brain; Cell-Free System; Chlorides; Ethanol; In Vitro Techniques; Ion Channels; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Synaptosomes | 1986 |
The action of taurine on the response to glutamate in the motoneuron of the isolated frog spinal cord.
Topics: Animals; Bicuculline; Chlorides; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Lithium; Motor Neurons; Ouabain; Picrotoxin; Potassium; Rana catesbeiana; Sodium; Spinal Cord; Strychnine; Taurine | 1985 |
gamma-Aminobutyric acid antagonists stimulate vasopressin release from organ-cultured hypothalamo-neurohypophyseal explants.
Topics: Acetylcholine; Animals; Bacitracin; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Ion Channels; Male; Nipecotic Acids; Organ Culture Techniques; Osmolar Concentration; Penicillins; Picrotoxin; Pituitary Gland, Posterior; Proline; Rats; Rats, Inbred Strains; Vasopressins | 1987 |
GABA receptors on the cell-body membrane of an identified insect motor neuron.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Chlorides; Cockroaches; Dibenzazepines; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Potentials; Microelectrodes; Motor Neurons; Nipecotic Acids; Periplaneta; Picrotoxin; Receptors, GABA-A | 1988 |
Convulsant-induced changes in perforant path-dentate gyrus excitability in urethane anesthetized rats.
Topics: Animals; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Hippocampus; Kainic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Contrasting properties of K+ conductances induced by baclofen and gamma-aminobutyric acid in slices of the guinea pig hippocampus.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Potentials; Picrotoxin; Potassium; Reference Values | 1987 |
gamma-Aminobutyric acid-induced ion movements in the guinea pig hippocampal slice.
Topics: Animals; Bicuculline; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Picrotoxin; Potassium; Sodium; Tetrodotoxin | 1989 |
Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons.
Topics: Animals; Anti-Bacterial Agents; Bicuculline; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Macrolides; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Sesterterpenes; Spinal Cord | 1989 |
Comparison of the responses to light and to GABA of cells postsynaptic to barnacle photoreceptors (I-cells).
Topics: Animals; Bicuculline; Cations, Divalent; Cimetidine; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Guanidines; Light; Osmolar Concentration; Photoreceptor Cells; Picrotoxin; Propionates; Synapses; Thoracica | 1989 |
Genotype-dependent effects of GABAergic agents on sedative properties of ethanol.
Topics: Animals; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Genetics, Behavioral; Genotype; Hypnotics and Sedatives; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Muscimol; Pentobarbital; Picrotoxin; Species Specificity | 1989 |
Convulsant properties of GABA antagonists and anticonvulsant properties of ethanol in selectively bred long- and short-sleep mice.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Ethanol; GABA Antagonists; Mice; Picrotoxin; Seizures | 1989 |
Chlordiazepoxide and valproate enhancement of saline drinking by nondeprived rats: effects of bicuculline, picrotoxin and Ro15-1788.
Topics: Animals; Bicuculline; Chlordiazepoxide; Dose-Response Relationship, Drug; Drinking Behavior; Drug Combinations; Drug Interactions; Flumazenil; Male; Picrotoxin; Rats; Rats, Inbred Strains; Sodium Chloride; Valproic Acid | 1989 |
GABAergic agents-induced antinociceptive effect in mice.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; Muscimol; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Valproic Acid | 1989 |
Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Cocaine; Electric Stimulation; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Neurons; Picrotoxin; Piperazines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tetrahydronaphthalenes | 1989 |
Effects of the acute and chronic administration of chlordiazepoxide on the development of spontaneous motility in chick embryos.
Topics: Animals; Bicuculline; Chick Embryo; Chlordiazepoxide; gamma-Aminobutyric Acid; Movement; Pentylenetetrazole; Picrotoxin; Strychnine; Time Factors | 1989 |
Growth hormone-releasing factor secretion from fetal hypothalamic cell cultures is modulated by forskolin, phorbol esters, and muscimol.
Topics: Animals; Bicuculline; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Growth Hormone-Releasing Hormone; Hypothalamus; Muscimol; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetradecanoylphorbol Acetate; Verapamil | 1989 |
[Effector modelling of the action of ligands of the GABA-receptor complex, cooperativity of the processes and the type of modification of the complex by convulsants and their reversible agonists].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbital; Bemegride; Benzodiazepines; Benzodiazepinones; Bicuculline; Convulsants; Drug Interactions; Female; Ligands; Mathematics; Mice; Mice, Inbred CBA; Models, Biological; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A | 1989 |
Effects of GABA antagonists on the pentobarbital-induced depression of respiration and cough in rats.
Topics: Animals; Bicuculline; Cough; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reflex; Respiration; Strychnine | 1989 |
The role of GABAA receptor function in peristaltic activity of the guinea-pig ileum: a comparative study with bicuculline, SR 95531 and picrotoxinin.
Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Peristalsis; Picrotoxin; Pyridazines; Receptors, GABA-A; Sesterterpenes | 1989 |
Influence of GABA and ethylenediamine in the guinea-pig duodenum.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Duodenum; Electric Stimulation; Ethylenediamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Thiosemicarbazones | 1989 |
Analysis of vertebrate eye movements following intravitreal drug injections. III. Spontaneous nystagmus is modulated by the GABAa receptor.
Topics: Animals; Bicuculline; Eye Movements; Muscimol; Nystagmus, Physiologic; Picrotoxin; Receptors, GABA-A; Turtles; Vitreous Body | 1989 |
Modulation of spontaneous motility by GABAA receptor antagonism in the guinea pig isolated ileum.
Topics: 3-Mercaptopropionic Acid; Acetylcholine; Androstanes; Animals; Azasteroids; Bicuculline; Carbachol; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Picrotoxin; Time Factors | 1989 |
[Effector modeling of the action of ligands of GABA-receptor complex. Functional interaction of the hypothetic alcohol receptor with other subunits of the complex].
Topics: 1-Propanol; Alcohols; Animals; Barbiturates; Bemegride; Bicuculline; Butanols; Ethanol; Female; Methanol; Mice; Mice, Inbred CBA; Models, Biological; Pentanols; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Semicarbazides | 1989 |
A progesterone metabolite enhances the activity of the GABAA receptor complex at the pituitary level.
Topics: 5-alpha-Dihydroprogesterone; Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Male; Membranes; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Pregnanediones; Progesterone; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Further evidence for the GABAergic influence on memory. Interaction of GABAergic transmission with angiotensin II on memory processes.
Topics: Angiotensin II; Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Muscimol; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission | 1989 |
[Effects of muscimol on aggressive behaviors induced by clonidine in mice].
Topics: Aggression; Animals; Behavior, Animal; Bicuculline; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Muscimol; Picrotoxin; Receptors, GABA-A | 1989 |
An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells.
Topics: Acetylcholine; Action Potentials; Adrenal Medulla; Androstanes; Animals; Azasteroids; Bicuculline; Cattle; Cell Membrane; Chloride Channels; Chlorides; Chromaffin System; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Proteins; Picrotoxin; Propanidid; Receptors, Cholinergic; Receptors, GABA-A | 1989 |
[The electrical activity of the hippocampus in rats centrally administered GABA agonists and antagonists].
Topics: Animals; Baclofen; Bicuculline; Drug Interactions; Electrodes, Implanted; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
A slow NMDA-mediated synaptic potential underlies seizures originating from midbrain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; In Vitro Techniques; Inferior Colliculi; N-Methylaspartate; Picrotoxin; Rats; Seizures; Valine | 1989 |
The role of inhibitory processes in the formation of functional properties of neurons in vibrissal projection zone of the cat somatosensory cortex.
Topics: Animals; Bicuculline; Cats; Evoked Potentials, Somatosensory; Glutamates; Glutamic Acid; Motion Perception; Neural Inhibition; Physical Stimulation; Picrotoxin; Sensory Thresholds; Somatosensory Cortex; Vibrissae | 1989 |
Giant synaptic potentials in immature rat CA3 hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Animals, Newborn; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Ketamine; Membrane Potentials; Phencyclidine; Picrotoxin; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Bicuculline and picrotoxin block gamma-aminobutyric acid-gated Cl- conductance by different mechanisms.
Topics: Animals; Bicuculline; Binding, Competitive; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Picrotoxin; Rana catesbeiana | 1985 |
Food intake suppressant effect of baclofen in rats.
Topics: Animals; Appetite Depressants; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Male; Metergoline; Phenoxybenzamine; Picrotoxin; Pimozide; Propranolol; Rats | 1989 |
Inhibition of proestrous LH surge and ovulation in rats evoked by stimulation of the medial raphe nucleus involves a GABA-mediated mechanism.
Topics: Animals; Bicuculline; Electric Stimulation; Electrodes, Implanted; Estrus; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Injections, Intraperitoneal; Injections, Intraventricular; Luteinizing Hormone; Methysergide; Ovulation; Picrotoxin; Pituitary Gland, Anterior; Proestrus; Raphe Nuclei; Rats; Serotonin | 1989 |
Modulatory roles of GABAergic mechanisms in post-rotatory nystagmus in the rabbit.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Nystagmus, Pathologic; Picrotoxin; Rabbits; Rotation; Semicarbazides; Strychnine; Time Factors | 1989 |
GABA- and glutamate-mediated synaptic potentials in rat dorsal raphe neurons in vitro.
Topics: Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Membranes; Muscimol; Picrotoxin; Raphe Nuclei; Rats; Synapses | 1989 |
Effects of microiontophoretically-applied morphine on the Purkinje cell in the cerebellum of the cat.
Topics: Animals; Bicuculline; Cats; Cerebellum; Female; GABA Antagonists; Iontophoresis; Male; Morphine; Naloxone; Picrotoxin; Purkinje Cells | 1989 |
Effects of naloxone and naltrexone on memory consolidation in CD1 mice: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Naltrexone; Picrotoxin | 1989 |
Inhibitory effect of intravenous GABA antagonists on gastric acid secretion stimulated by secretagogues in rats.
Topics: Animals; Bethanechol Compounds; Bicuculline; Deoxyglucose; GABA Antagonists; Gastric Acid; Injections, Intravenous; Male; Paralysis; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord Injuries; Stomach; Strychnine; Tubocurarine | 1989 |
RO15-4513 but not FG-7142 reverses anticonvulsant effects of ethanol against bicuculline- and picrotoxin-induced convulsions in rats.
Topics: Affinity Labels; Animals; Appetite Depressants; Azides; Benzodiazepines; Bicuculline; Carbolines; Ethanol; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1989 |
The pentylenetetrazol-like interoceptive stimulus produced by ethanol withdrawal is potentiated by bicuculline and picrotoxinin.
Topics: Animals; Anxiety; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; GABA Antagonists; Male; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Sesterterpenes; Substance Withdrawal Syndrome | 1989 |
gamma-Aminobutyric acid regulation of neurohypophysial hormone secretion in male and female rats.
Topics: Animals; Arginine Vasopressin; Bicuculline; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Oxytocin; Picrotoxin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Time Factors; Veratridine | 1989 |
Effects of the diterpene sclareol glycol on convulsive seizures.
Topics: Animals; Bicuculline; Colforsin; Convulsants; Diterpenes; Drug Synergism; Male; Mice; Pentylenetetrazole; Picrotoxin; Seizures | 1989 |
Effects of depressant amino acids and antagonists on an in vitro spinal cord preparation from the adult rat.
Topics: Action Potentials; Amino Acids; Animals; Bicuculline; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; Picrotoxin; Piperazines; Rats; Spinal Cord; Strychnine; Synapses; Taurine; Valine | 1989 |
GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla.
Topics: Animals; Bicuculline; Dioxanes; Evoked Potentials; gamma-Aminobutyric Acid; Idazoxan; Iontophoresis; Locus Coeruleus; Male; Medulla Oblongata; Naloxone; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains | 1989 |
Ethanol potentiates the effect of gamma-aminobutyric acid on medial vestibular nucleus neurons responding to horizontal rotation.
Topics: Animals; Bicuculline; Cats; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Ethanol; gamma-Aminobutyric Acid; Male; Neural Inhibition; Neurons; Picrotoxin; Rotation; Vestibular Nuclei | 1989 |
Release pattern of endogenous dopamine in teleost retinae during light adaptation and pharmacological stimulation.
Topics: Adaptation, Ocular; Animals; Bicuculline; Carps; Chromatography, High Pressure Liquid; Cyprinidae; Dopamine; gamma-Aminobutyric Acid; Glutamates; Kynurenic Acid; Photic Stimulation; Picrotoxin; Retina; Taurine | 1989 |
GABAA receptor complexes are present on both sides of a GABA-acceptive neuronal membrane.
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; Homeostasis; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A; Vestibular Nuclei; Vestibular Nucleus, Lateral | 1987 |
Antagonists of GABA responses, studied using internally perfused frog dorsal root ganglion neurons.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Penicillins; Picrotoxin; Rana catesbeiana; Receptors, GABA-A; Zinc | 1987 |
Studies on [3H]GABA and endogenous GABA release in rat cerebral cortex suggest the presence of autoreceptors of the GABAB type.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Median Eminence; Nipecotic Acids; Picrotoxin; Potassium; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1987 |
GABAA and GABAB receptor sites involvement in rat thermoregulation.
Topics: Animals; Baclofen; Bicuculline; Body Temperature Regulation; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Isonicotinic Acids; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A | 1988 |
Neuroeffector mechanisms in the voiding cycle of the guinea-pig urinary bladder.
Topics: Animals; Atropine; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Neuroeffector Junction; Physostigmine; Picrotoxin; Receptors, Cholinergic; Receptors, GABA-A; Synaptic Transmission; Urinary Bladder; Urodynamics | 1987 |
Effects of ethanol on passive avoidance behavior in the mouse: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Male; Memory; Mice; Muscimol; Picrotoxin; Receptors, GABA-A | 1988 |
[Effector modeling of the action of GABA-receptor complex ligands. Functional interactions of subunits of the complex].
Topics: Animals; Barbital; Benzodiazepines; Bicuculline; Dose-Response Relationship, Drug; Ligands; Male; Mice; Mice, Inbred CBA; Models, Biological; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A | 1988 |
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1988 |
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Indomethacin; Male; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Taurine | 1988 |
[Effector modeling of the effect of ligands of GABA receptor complex. Modification of conformation states of the complex by combined administration of benzodiazepines and barbiturates].
Topics: Animals; Anti-Anxiety Agents; Barbital; Barbiturates; Benzodiazepines; Benzodiazepinones; Bicuculline; Diazepam; Drug Antagonism; Female; Ligands; Mice; Models, Biological; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A | 1988 |
Direct evidence for the presence of GABAA receptors on the cytoplasmic side of the Deiters' neurone membrane.
Topics: Animals; Bicuculline; Chlorides; Cytoplasm; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Picrotoxin; Rabbits; Receptors, GABA-A | 1988 |
Interactions of pentobarbital and phenobarbital with GABAergic drugs against chemoconvulsants in rats.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Diazepam; Drug Interactions; Isoxazoles; Male; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Strychnine | 1988 |
Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice.
Topics: Amnesia; Animals; Avoidance Learning; Baclofen; Bicuculline; Butylscopolammonium Bromide; Cycloheximide; Male; Mice; Muscimol; Physostigmine; Picrotoxin; Receptors, Cholinergic; Receptors, GABA-A; Scopolamine | 1988 |
[Proconvulsant effect of morphine on seizures induced by pentylenetetrazol in the mice].
Topics: Animals; Bicuculline; Convulsants; Drug Synergism; Male; Mice; Morphine; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A | 1988 |
Two inhibitory postsynaptic potentials, and GABAA and GABAB receptor-mediated responses in neocortex of rat and cat.
Topics: Action Potentials; Animals; Baclofen; Barium; Bicuculline; Cats; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Neurons; Picrotoxin; Rats; Receptors, GABA-A; Somatosensory Cortex; Synapses; Time Factors; Visual Cortex | 1988 |
Central GABA-ergic mechanism in stress-induced gastric ulceration.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cold Temperature; Epinephrine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Injections, Intraventricular; Male; Neurotransmitter Agents; Picrotoxin; Pylorus; Rats; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Valproic Acid | 1985 |
Somatostatin and GABA correlate with cervical autonomic nerve activity.
Topics: Animals; Atropine; Autonomic Nervous System; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Hemodynamics; Injections, Intraventricular; Laryngeal Nerves; Male; Picrotoxin; Rats; Rats, Inbred Strains; Reserpine; Somatostatin | 1985 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: punished barpressing.
Topics: Amobarbital; Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Bicuculline; Carbolines; Chlordiazepoxide; Drug Interactions; Humans; Male; Muscimol; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1985 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: choice behaviour in the T-maze.
Topics: Animals; Anti-Anxiety Agents; Baclofen; Bicuculline; Chlordiazepoxide; Choice Behavior; Exploratory Behavior; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Biphasic effects of glycine on synaptic responses of the frog optic tectum in vitro.
Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Picrotoxin; Rana temporaria; Superior Colliculi; Synapses; Synaptic Transmission | 1986 |
Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Bicuculline; Carbolines; Cells, Cultured; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Nitrazepam; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1986 |
The role of GABA and excitatory amino acids in the development of the leptazol-induced epileptogenic EEG.
Topics: Allylglycine; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Clonazepam; Dose-Response Relationship, Drug; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1986 |
Effect of inferior olive lesion on seizure threshold in the rat.
Topics: Animals; Bicuculline; Cerebellum; Convulsants; Male; Motor Activity; Neural Pathways; Olivary Nucleus; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Seizures; Strychnine | 1987 |
Effects of barbiturates on the inhibitory action of GABA on excitatory response of the stomach to stimulation of vagal afferent fibers in cat.
Topics: Afferent Pathways; Animals; Bicuculline; Cats; Chloralose; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hexamethonium; Hexamethonium Compounds; Kinetics; Male; Phenobarbital; Picrotoxin; Stomach; Vagus Nerve | 1987 |
Involvement of N-methyl-D-aspartate receptors in epileptiform bursting in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Bicuculline; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1986 |
GABAergic, dopaminergic and cholinergic interaction in tremorine-induced tremors in mice.
Topics: Animals; Bicuculline; Bromocriptine; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Parasympathetic Nervous System; Picrotoxin; Scopolamine; Tremor; Tremorine | 1988 |
Pharmacologically induced changes in the latency of digastric reflexes in 1-7 day old rabbits.
Topics: Animals; Animals, Newborn; Bicuculline; Decerebrate State; Diazepam; Electromyography; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rabbits; Reflex; Stomach; Strychnine; Synaptic Transmission | 1988 |
Epileptiform events induced by GABA-antagonists in entorhinal cortical cells in vitro are partly mediated by N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Cerebral Cortex; Epilepsy; In Vitro Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Benzodiazepines increase tonic component of postdecapitation convulsions in mice.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Decerebrate State; Flumazenil; Male; Mice; Mice, Inbred Strains; Picrotoxin; Receptors, GABA-A; Seizures | 1988 |
Evidence that glycine mediates the postsynaptic potentials that inhibit lumbar motoneurons during the atonia of active sleep.
Topics: Animals; Bicuculline; Cats; Electrophysiology; Glycine; Iontophoresis; Lumbosacral Region; Motor Neurons; Muscle Tonus; Neural Inhibition; Picrotoxin; Sleep; Strychnine; Synapses | 1989 |
Role of the cat substantia nigra pars reticulata in eye and head movements. II. Effects of local pharmacological injections.
Topics: Animals; Bicuculline; Cats; Eye Movements; gamma-Aminobutyric Acid; Movement; Muscimol; Orientation; Picrotoxin; Reflex; Substantia Nigra; Synaptic Transmission | 1985 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
Effect of GABA and its antagonists, bicuculline and picrotoxin, on nerve cell discharges of the photosensory pineal organ of the frog, Rana esculenta.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Light; Picrotoxin; Pineal Gland; Rana esculenta; Synaptic Transmission | 1985 |
Modulatory activity of GABAB receptors on cholinergic tone in guinea-pig distal colon.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Atropine; Baclofen; Bicuculline; Blood Pressure; Colon; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Male; Parasympathetic Nervous System; Picrotoxin; Receptors, GABA-A | 1985 |
Evidence for gamma-aminobutyric acid mediation of the sympathetic nerve inhibitory response to vagal afferent stimulation.
Topics: Afferent Pathways; Animals; Bicuculline; Blood Pressure; Cats; Diazepam; Female; gamma-Aminobutyric Acid; Heart; Male; Neural Inhibition; Picrotoxin; Receptors, GABA-A; Reflex; Sympathetic Nervous System; Urethane; Vagus Nerve | 1985 |
gamma-Aminobutyric acid partly mediates the pentobarbitone depression of synaptic excitation in the guinea-pig olfactory cortex in vitro.
Topics: Animals; Bicuculline; Drug Interactions; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Limbic System; Male; Membrane Potentials; Olfactory Pathways; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1985 |
Stimulation of vasopressin release by gamma-aminobutyric acid antagonists in spinal cord transected rats.
Topics: Animals; Arginine Vasopressin; Bicuculline; Blood Pressure; Decerebrate State; GABA Antagonists; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A; Spinal Cord | 1985 |
Evidence for GABA mediation of sympathetic inhibition evoked from midline medullary depressor sites.
Topics: Animals; Bicuculline; Brain Mapping; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Neural Inhibition; Picrotoxin; Raphe Nuclei; Serotonin; Synaptic Transmission; Vasomotor System | 1985 |
An unusual effect of gamma-aminobutyric acid on synaptic transmission of frog tectal neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Hot Temperature; In Vitro Techniques; Muscimol; Neurons; Optic Nerve; Picrotoxin; Rana temporaria; Strychnine; Superior Colliculi; Synaptic Transmission | 1985 |
Inhibition of intrathecally administered picrotoxin- and bicuculline-induced convulsions in mice by pipecolic acid or GABA.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Nipecotic Acids; Picrotoxin; Pipecolic Acids; Proline; Receptors, GABA-A; Seizures; Strychnine | 1985 |
[Nature of a mediator participating in reflex inhibition of the activity of the lymphatic center of the frog].
Topics: Ammonium Chloride; Animals; Bicuculline; Furosemide; gamma-Aminobutyric Acid; In Vitro Techniques; Lymphatic System; Neural Inhibition; Picrotoxin; Rana temporaria; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1985 |
Memory effects of GABA-ergic antagonists in rats trained with two-way active avoidance tasks.
Topics: Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Picrotoxin; Rats; Rats, Inbred Strains; Synaptic Transmission | 1985 |
Facilitation of hippocampal long-lasting potentiation by GABA antagonists.
Topics: Afferent Pathways; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Muscle Contraction; Penicillins; Picrotoxin; Receptors, GABA-A; Synapses; Synaptic Transmission | 1985 |
Involvement of bicuculline-insensitive receptors in the hypothermic effect of GABA and its agonists.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Body Temperature; Drug Interactions; Female; gamma-Aminobutyric Acid; Hypothermia; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors; Valproic Acid | 1985 |
Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes.
Topics: Amobarbital; Animals; Barbiturates; Bicuculline; Brain; Cell Membrane Permeability; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Hexobarbital; Male; Mephobarbital; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Rubidium; Secobarbital; Synapses | 1985 |
Antagonist actions of bicuculline methiodide and picrotoxin on extrasynaptic gamma-aminobutyric acid receptors.
Topics: Animals; Bicuculline; Evoked Potentials; In Vitro Techniques; Picrotoxin; Rana pipiens; Receptors, GABA-A | 1985 |
[Effect of gamma-aminobutyric acid on neurons of the spinal lymphatic center].
Topics: Ammonium Chloride; Animals; Bicuculline; Furosemide; gamma-Aminobutyric Acid; Lymphatic System; Picrotoxin; Rana temporaria; Spinal Cord; Synaptic Transmission | 1985 |
GABA antagonists increase the release of [3H]acetylcholine from the chick retina.
Topics: Acetylcholine; Animals; Bicuculline; Chickens; Choline; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Haloperidol; In Vitro Techniques; Photic Stimulation; Picrotoxin; Potassium; Receptors, GABA-A; Retina; Strychnine | 1986 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: extinction and successive discrimination.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Chlordiazepoxide; Discrimination Learning; Discrimination, Psychological; Drug Interactions; Extinction, Psychological; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors | 1986 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
GABAergic control of masculine sexual behavior.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Caudate Nucleus; Ethanolamines; gamma-Aminobutyric Acid; Male; Picrotoxin; Preoptic Area; Putamen; Rats; Sexual Behavior, Animal; Synaptic Transmission | 1986 |
Activation of GABA receptors in the hypothalamus stimulates secretion of growth hormone and prolactin.
Topics: Animals; Anterior Hypothalamic Nucleus; Bicuculline; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; Male; Microinjections; Muscimol; Picrotoxin; Preoptic Area; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Proconflict effect of GABA receptor complex antagonists. Reversal by diazepam.
Topics: Animals; Benzodiazepinones; Bicuculline; Conflict, Psychological; Diazepam; Flumazenil; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.
Topics: Animals; Bicuculline; Body Temperature; Carbolines; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1986 |
2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--I. Anticonvulsant properties.
Topics: Amino Acids; Animals; Anticonvulsants; Bicuculline; Electroshock; Female; Glutamate Decarboxylase; Harmaline; Male; Mice; Mice, Inbred DBA; Ouabain; Papio; Pentylenetetrazole; Picrotoxin; Rats; Riluzole; Seizures; Synaptic Transmission; Thiazoles | 1985 |
Nociceptive responses to altered GABAergic activity at the spinal cord.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Spinal; Motor Activity; Muscimol; Pain; Pain Measurement; Physical Stimulation; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds; Tail; Vocalization, Animal | 1986 |
Benzodiazepines inhibit thyrotropin (TSH)-releasing hormone-induced TSH and growth hormone release from perifused rat pituitaries.
Topics: Animals; Benzodiazepines; Bicuculline; Diazepam; Flumazenil; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Isoquinolines; Male; Picrotoxin; Pituitary Gland, Anterior; Rats; Receptors, GABA-A; Secretory Rate; Thyrotropin; Thyrotropin-Releasing Hormone | 1986 |
Comparison of anticonvulsant effect of pentobarbital and phenobarbital against seizures induced by maximal electroshock and picrotoxin in rats.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Anticonvulsants; Bicuculline; Electroshock; Male; Muscimol; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1986 |
Expression of vertebrate amino acid receptors in Xenopus oocytes.
Topics: Animals; Bicuculline; Chick Embryo; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression Regulation; Picrotoxin; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA, Messenger; Strychnine; Xenopus laevis | 1986 |
Potentiation of salivary fluid secretion in ixodid ticks: a new receptor system for gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Dopamine; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Picrotoxin; Receptors, GABA-A; Saliva; Spiperone; Sulpiride; Ticks | 1986 |
gamma-Aminobutyric acid-activated 36Cl- influx: a functional in vitro assay for CNS gamma-aminobutyric acid receptors of insects.
Topics: Animals; Bicuculline; Chlorides; Cockroaches; Electrophysiology; gamma-Aminobutyric Acid; Nervous System; Periplaneta; Picrotoxin; Receptors, GABA-A | 1987 |
GABA-ergic control of alpha-melanocyte-stimulating hormone (alpha-MSH) release by frog neurointermediate lobe in vitro.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunoenzyme Techniques; Male; Melanocyte-Stimulating Hormones; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Rana ridibunda; Synaptic Transmission | 1986 |
Cyclodiene insecticides inhibit GABAA receptor-regulated chloride transport.
Topics: Animals; Bicuculline; Biological Transport; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Insecticides; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
The dopamine-gamma aminobutyric acid interaction in the striatum of the rat is differently regulated by dopamine D-1 and D-2 types of receptor: evidence obtained with rotational behavioural experiments.
Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; Corpus Striatum; Hydroxydopamines; Ibotenic Acid; Male; Muscimol; Nipecotic Acids; Oxidopamine; Pergolide; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Rotation | 1987 |
Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1987 |
The role of gamma-aminobutyric acid mechanisms of the zona incerta-lateral hypothalamus in the catalepsy and muscle rigidity evoked by morphine.
Topics: Animals; Bicuculline; Catalepsy; Hypothalamic Area, Lateral; Male; Morphine; Muscle Rigidity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei | 1987 |
Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats.
Topics: Aggression; Animals; Bicuculline; Brain Mapping; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Posterior; Isoniazid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Synaptic Transmission | 1987 |
Regulation of dopamine release from interplexiform cell processes in the outer plexiform layer of the carp retina.
Topics: Animals; Autoradiography; Bicuculline; Calcium; Cyclic AMP; Dopamine; Fishes; Picrotoxin; Retina | 1987 |
Blockade of gamma-aminobutyric acid-receptors of the B-subtype inhibits the dopamine-induced enhancement of the release of cholecystokinin-like immunoreactivity from slices of rat dorsal caudatoputamen.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Caudate Nucleus; Cholecystokinin; Dopamine Antagonists; In Vitro Techniques; Indicators and Reagents; Male; Muscimol; Picrotoxin; Putamen; Rats; Rats, Inbred Strains; Receptors, GABA-A; Veratridine | 1987 |
Sex differences in the sensitivity of CBA mice to convulsions induced by GABA antagonists are age-dependent.
Topics: Aging; Animals; Bicuculline; Female; GABA Antagonists; Male; Mice; Mice, Inbred CBA; Picrotoxin; Seizures; Sex Factors; Strychnine | 1987 |
Analgesic effects of the progesterone metabolite, 3 alpha-hydroxy-5 alpha-pregnan-20-one, and possible modes of action in mice.
Topics: Analgesics; Animals; Bicuculline; Brain; Calcium Channel Blockers; Flumazenil; Injections, Intraventricular; Male; Mice; Naloxone; Picrotoxin; Progesterone | 1987 |
Evidence for a dual effect of gamma-aminobutyric acid on thyrotropin (TSH)-releasing hormone-induced TSH release from perifused rat pituitaries.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Pyridazines; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone | 1987 |
Valproate enhances inhibitory postsynaptic potentials in hippocampal neurons in vitro.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Picrotoxin; Synapses; Valproic Acid | 1987 |
Microgram doses of diazepam do not induce proconvulsant or proconflict effects in rodents.
Topics: Animals; Bicuculline; Conditioning, Operant; Diazepam; Isoniazid; Mice; Pentylenetetrazole; Picrotoxin; Punishment; Seizures | 1987 |
Microinjection of GABA antagonists into the posterior hypothalamus elicits locomotor activity and a cardiorespiratory activation.
Topics: Animals; Bicuculline; Blood Pressure; Carbon Dioxide; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Microinjections; Muscimol; Picrotoxin; Respiration; Tidal Volume | 1988 |
Post-training administration of GABAergic antagonists enhances retention of aversively motivated tasks.
Topics: Animals; Bicuculline; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Electroshock; GABA Antagonists; Male; Mice; Mice, Inbred Strains; Picrotoxin; Reinforcement, Psychology; Seizures | 1988 |
Amygdaloid kindling with bicuculline methiodide in rats.
Topics: Amygdala; Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture.
Topics: Animals; Bicuculline; Cells, Cultured; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Mice; Mice, Inbred C57BL; Picrotoxin; Rats; Retina; Retinal Ganglion Cells; Strychnine; Taurine | 1988 |
GABAA-antagonists and baclofen analgesia.
Topics: Analgesia; Animals; Baclofen; Bicuculline; GABA Antagonists; Injections, Intraperitoneal; Male; Mice; Morphine; Naloxone; Picrotoxin; Time Factors | 1988 |
Alfaxalone potentiates and mimics GABA-induced contractile responses in the guinea-pig isolated ileum.
Topics: Anesthetics; Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Picrotoxin; Pregnanediones; Sesterterpenes | 1988 |
GABAergic inhibition and epileptiform discharges in the turtle hippocampus in vitro.
Topics: Afferent Pathways; Animals; Bicuculline; Electric Stimulation; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Pipecolic Acids; Pyramidal Tracts; Reference Values; Synapses; Turtles | 1988 |
Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice.
Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Ethanol; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Picrotoxin; Seizures; Substance Withdrawal Syndrome | 1988 |
GABA antagonists potentiate the cardioinhibitory reflex induced by capsaicin in the cat.
Topics: Animals; Bicuculline; Blood Pressure; Capsaicin; Cats; Decerebrate State; Drug Synergism; GABA Antagonists; Heart; Heart Rate; Picrotoxin; Reflex; Respiration | 1988 |
GABAergic inhibition on dopamine cells of the fish retina: a [3H]dopamine release study with isolated fractions.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Bicuculline; Calcium; Carps; Cyprinidae; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Picrotoxin; Potassium; Retina | 1988 |
Interactions of the imidazodiazepine Ro 15-4513 with chemical convulsants.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Bicuculline; Carbolines; Convulsants; Drug Interactions; Male; Mice; Pentylenetetrazole; Picrotoxin; Seizures | 1988 |
Hypothalamic GABA suppresses sympathetic outflow to the cardiovascular system.
Topics: Animals; Bicuculline; Blood Pressure; GABA Antagonists; Heart Rate; Hypothalamus; Male; Muscimol; Nitroprusside; Phenylephrine; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Sympathetic Nervous System | 1988 |
"Intracellular" GABA affects the equilibrium distribution of Cl- across the plasma membrane of a GABA acceptive neuron.
Topics: Animals; Bicuculline; Cell Membrane; Cell Membrane Permeability; Chlorides; gamma-Aminobutyric Acid; Intracellular Membranes; Neurons; Picrotoxin; Time Factors; Vestibular Nucleus, Lateral | 1988 |
Dopamine function in the prefrontal cortex of the rat is sensitive to a reduction of tonic GABA-mediated inhibition in the thalamic mediodorsal nucleus.
Topics: Animals; Bicuculline; Dopamine; Frontal Lobe; gamma-Aminobutyric Acid; Ibotenic Acid; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains; Thalamic Nuclei | 1988 |
Circadian regulation of retinomotor movements: II. The role of GABA in the regulation of cone position.
Topics: Animals; Bicuculline; Circadian Rhythm; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Melatonin; Muscimol; Photoreceptor Cells; Picrotoxin; Xenopus laevis | 1988 |
Characterization of synaptically mediated fast and slow inhibitory processes in piriform cortex in an in vitro slice preparation.
Topics: Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Picrotoxin; Potassium; Rats; Reaction Time; Synapses | 1988 |
Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation.
Topics: 3-Mercaptopropionic Acid; Anesthesia; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Male; Pentobarbital; Pentylenetetrazole; Perfusion; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Biphasic responses of thalamic neurons to GABA in isolated rat brain slices--II.
Topics: Animals; Bicuculline; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Picrotoxin; Rats; Thalamus | 1988 |
Electrical and chemical activation of the mesencephalic and subthalamic locomotor regions in freely moving rats.
Topics: Amino Acids; Animals; Bicuculline; Brain Mapping; Brain Stem; Carbachol; Electric Stimulation; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1988 |
Pharmacological analysis of the magnocellular red nucleus during classical conditioning of the rabbit nictitating membrane response.
Topics: Animals; Bicuculline; Conditioning, Classical; Electric Stimulation; Male; Nictitating Membrane; Picrotoxin; Rabbits; Red Nucleus; Retention, Psychology; Strychnine | 1988 |
The rabbit electroretinogram: effect of GABA and its antagonists.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Photic Stimulation; Picrotoxin; Rabbits; Retina; Time Factors | 1988 |
gamma-Aminobutyric acid antagonist blocks baroreceptor-activated inhibition of neurosecretory cells in the hypothalamic paraventricular nucleus of rats.
Topics: Action Potentials; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neurosecretory Systems; Paraventricular Hypothalamic Nucleus; Phenylephrine; Picrotoxin; Pressoreceptors; Rats; Rats, Inbred Strains; Strychnine | 1987 |
A synaptically evoked late hyperpolarization in the rat dorsolateral geniculate neurons in vitro.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Electric Stimulation; Female; Geniculate Bodies; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Optic Nerve; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Synapses; Visual Pathways | 1987 |
Corticofugal inhibitory effects on lingually induced postsynaptic potentials in cat hypoglossal motoneurons.
Topics: Action Potentials; Animals; Bicuculline; Cats; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Female; Hypoglossal Nerve; Lingual Nerve; Male; Mandibular Nerve; Motor Neurons; Neural Inhibition; Picrotoxin; Reaction Time | 1987 |
GABA-ergic mechanisms in the anticonvulsive activity of newly-synthesized barbiturates. I. Effects of barbiturates on the convulsive action of GABA-antagonists.
Topics: 3-Mercaptopropionic Acid; Allylglycine; Animals; Anticonvulsants; Barbiturates; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Picrotoxin; Rats; Seizures; Semicarbazides | 1987 |
[Effects of systemic administration of strychnine, L-allylglycine, bicuculline and picrotoxin on the transsynaptic neural destruction in the medullary dorsal horn following transection of the rat inferior alveolar nerve].
Topics: Allylglycine; Animals; Bicuculline; Glycine; Male; Mandibular Nerve; Medulla Oblongata; Nerve Degeneration; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1987 |
Anisotropic inhibition in the receptive field surround of the frog retinal ganglion cells, evidenced by bicuculline and SR 95103, a new GABA antagonist.
Topics: Animals; Bicuculline; Electroretinography; GABA Antagonists; Ganglia; In Vitro Techniques; Microelectrodes; Photic Stimulation; Picrotoxin; Pyridazines; Rana temporaria; Retina; Time Factors | 1986 |
A simple in vitro method to study the trigeminal ganglion.
Topics: Action Potentials; Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rats; Trigeminal Ganglion; Trigeminal Nerve | 1986 |
Is GABA an afferent transmitter in the vestibular system?
Topics: Afferent Pathways; Ambystoma mexicanum; Animals; Bicuculline; Electric Stimulation; Evoked Potentials, Auditory; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Nerve Fibers; Picrotoxin; Vestibule, Labyrinth | 1987 |
Voltage-clamp studies of the inhibition of gamma-aminobutyric acid response by glucocorticoids in bullfrog primary afferent neurons.
Topics: Afferent Pathways; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Kinetics; Neurons; Picrotoxin; Prednisolone; Rana catesbeiana | 1987 |
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurons, Afferent; Pentobarbital; Picrotoxin; Rana catesbeiana | 1987 |
Interactions of acoustic and somatosensory evoked responses in a polysensory cortex of the cat.
Topics: Acoustic Stimulation; Amphetamine; Animals; Baclofen; Bicuculline; Cats; Diazepam; Electric Stimulation; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Glutamine; Haloperidol; Microelectrodes; Neurons; Parathyroid Hormone; Picrotoxin; Reserpine; Somatosensory Cortex; Taurine | 1987 |
In vitro studies of the role of gamma-aminobutyric acid in inhibition in the lateral septum of the rat.
Topics: Animals; Bicuculline; Brain; Calcium; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Reference Values; Tetrodotoxin | 1987 |
Effect of inhibitory amino acid antagonists on masseteric reflex suppression during active sleep.
Topics: Amino Acids; Animals; Bicuculline; Cats; GABA Antagonists; Glycine; Masticatory Muscles; Membrane Potentials; Picrotoxin; Reflex, Monosynaptic; Sleep Stages; Strychnine; Trigeminal Nuclei; Wakefulness | 1987 |
Spinal and supraspinal components of GABAergic inhibition of the micturition reflex in rats.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Taurine; Urination | 1987 |
gamma-Aminobutyric acid stimulates pituitary growth hormone secretion in the neonatal rat. A superfusion study.
Topics: Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; In Vitro Techniques; Kinetics; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Rats; Rats, Inbred Strains | 1987 |
Seizure activity and cortical spreading depression monitored by an extrinsic potential-sensitive molecular probe.
Topics: Animals; Bicuculline; Cerebral Cortex; Cortical Spreading Depression; Electrophysiology; Female; Gerbillinae; Male; Mitochondria; Picrotoxin; Potassium Chloride; Seizures | 1987 |
Uptake inhibitors potentiate gamma-aminobutyric acid-induced contractile responses in the isolated ileum of the guinea-pig.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Sesterterpenes; Taurine | 1987 |
Multiple mechanisms of antagonism of gamma-aminobutyric acid (GABA) responses.
Topics: Animals; Bicuculline; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Penicillins; Picrotoxin; Ranidae; Zinc | 1987 |
Participation of angiotensin II in learning and memory. III. Interactions of angiotensin II with GABAergic drugs.
Topics: Angiotensin II; Animals; Bicuculline; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Intraventricular; Learning; Male; Memory; Picrotoxin; Rats; Rats, Inbred Strains | 1987 |
Specific binding of 36Cl- ions to rat cerebellar membranes: effect of GABA and S-100 protein.
Topics: Animals; Bicuculline; Cerebellum; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Male; Membranes; Picrotoxin; Rats; Rats, Inbred Strains; S100 Proteins; Synaptic Membranes | 1987 |
Picrotoxin but not bicuculline antagonizes 5-hydroxytryptamine-induced inhibition of cerebellar Purkinje neurons.
Topics: Action Potentials; Animals; Bicuculline; Calcium; In Vitro Techniques; Magnesium; Male; Neural Inhibition; Nipecotic Acids; Picrotoxin; Proline; Purkinje Cells; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Rapid transneuronal destruction following peripheral nerve transection in the medullary dorsal horn is enhanced by strychnine, picrotoxin and bicuculline.
Topics: Animals; Bicuculline; Nerve Degeneration; Neurons; Peripheral Nerve Injuries; Peripheral Nerves; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1987 |
Effect of inhibitory amino acid antagonists on IPSPs induced in lumbar motoneurons upon stimulation of the nucleus reticularis gigantocellularis during active sleep.
Topics: Animals; Bicuculline; Cats; Evoked Potentials; GABA Antagonists; Glycine; Motor Neurons; Picrotoxin; Reticular Formation; Sleep; Spinal Cord; Strychnine; Synapses | 1987 |
Effect of GABAergic drugs in the behavioral 'despair' test in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Muscimol; Oxazoles; Picrotoxin; Rats | 1986 |
Behavioral function of GABA in the median raphe nucleus.
Topics: Animals; Bicuculline; Cyproheptadine; Dihydrotestosterone; GABA Antagonists; gamma-Aminobutyric Acid; Haloperidol; Lysergic Acid Diethylamide; Male; Motor Activity; Muscimol; Picrotoxin; Raphe Nuclei; Rats | 1986 |
Effects of diethylcarbamazine on the motility of Angiostrongylus cantonensis and Dirofilaria immitis.
Topics: Angiostrongylus; Animals; Bicuculline; Dibenzylchlorethamine; Diethylcarbamazine; Dimethylphenylpiperazinium Iodide; Dirofilaria immitis; Dogs; Female; Filarioidea; Hexylresorcinol; Metastrongyloidea; Movement; Phentolamine; Physostigmine; Picrotoxin; Piperazine; Piperazines; Pyrantel Tartrate; Rats; Rats, Inbred Strains; Strychnine | 1986 |
Mechanisms by which picrotoxin and a high dose of diazepam elevate plasma corticosterone level.
Topics: Animals; Apomorphine; Atropine; Bicuculline; Clonidine; Corticosterone; Dexamethasone; Diazepam; Drug Interactions; Female; Haloperidol; Picrotoxin; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
Differences in cardiovascular responses to peripherally administered GABA as influenced by basal conditions and type of anaesthesia.
Topics: Adrenal Medulla; Adrenalectomy; Anesthesia; Animals; Barbital; Bicuculline; Blood Pressure; Catecholamines; gamma-Aminobutyric Acid; Guinea Pigs; Heart Rate; Hemodynamics; Hexamethonium Compounds; Male; Myocardial Contraction; Picrotoxin; Reserpine; Urethane | 1986 |
Effects of gamma-aminobutyric acid on isolated cone photoreceptors of the turtle retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Photoreceptor Cells; Picrotoxin; Time Factors; Turtles | 1986 |
Antagonism of acute feeding response to 2-deoxyglucose and 5-thioglucose by GABA antagonists: the relative role of ventromedial and lateral hypothalamus.
Topics: Animals; Bicuculline; Deoxy Sugars; Deoxyglucose; Feeding Behavior; gamma-Aminobutyric Acid; Glucose; Hypothalamic Area, Lateral; Hypothalamus; Hypothalamus, Middle; Male; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
Kindling induced changes in EEG recorded during stimulation from the site of stimulation: collapse of GABA-mediated inhibition and onset of rhythmic synchronous burst.
Topics: Action Potentials; Amygdala; Animals; Bicuculline; Carbolines; Cerebral Cortex; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
GABAergic drugs can enhance or attenuate chlordiazepoxide-induced sleep time in a heterogeneous strain of mice.
Topics: Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Chlordiazepoxide; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Pentylenetetrazole; Picrotoxin; Sleep | 1986 |
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission.
Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Morphine; Muscimol; Neural Pathways; Pain; Pain Measurement; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
Increase in catecholamine release and 45Ca2+ uptake induced by GABA in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Bicuculline; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; gamma-Aminobutyric Acid; Nifedipine; Picrotoxin | 1986 |
Dopamine inhibits calcium-independent gamma-[3H]aminobutyric acid release induced by kainate and high K+ in the fish retina.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Dopamine; Fishes; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; N-Methylaspartate; Oxadiazoles; Picrotoxin; Potassium; Pyrrolidines; Quisqualic Acid; Retina; Serotonin | 1985 |
Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate.
Topics: Animals; Anticonvulsants; Bicuculline; Electroshock; Ethosuximide; Male; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures; Valproic Acid | 1985 |
Spiro[4.5] and spiro[4.6] carboxylic acids: cyclic analogues of valproic acid. Synthesis and anticonvulsant evaluation.
Topics: Animals; Anticonvulsants; Bicuculline; Carboxylic Acids; Male; Mice; Pentylenetetrazole; Picrotoxin; Spiro Compounds; Structure-Activity Relationship; Valproic Acid | 1985 |
An analysis of the in vivo interactions between chemical convulsants and anticonvulsants.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Valproic Acid | 1985 |
Injections of picrotoxin and bicuculline into the amygdaloid complex of the rat: an electroencephalographic, behavioural and morphological analysis.
Topics: Amygdala; Animals; Behavior, Animal; Bicuculline; Drug Interactions; Electroencephalography; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1985 |
Antagonism of inhibitory amino acids by the steroid derivative RU5135.
Topics: Amino Acids; Androstanes; Animals; Azasteroids; Bicuculline; Electrophysiology; Glycine; In Vitro Techniques; Medulla Oblongata; Muscimol; Optic Nerve; Picrotoxin; Rats; Steroids, Heterocyclic; Strychnine | 1985 |
Chemical activation of the mesencephalic locomotor region.
Topics: Animals; Bicuculline; Brain Mapping; Cats; Efferent Pathways; Electric Stimulation; gamma-Aminobutyric Acid; Locomotion; Models, Neurological; Picrotoxin; Spinal Cord; Tegmentum Mesencephali | 1985 |
gamma-Amino butyric-N-acid sensitivity of mouse and human oocytes.
Topics: Animals; Bicuculline; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ions; Metaphase; Mice; Mice, Inbred Strains; Oocytes; Picrotoxin; Zygote | 1985 |
Changes in local cerebral glucose utilization induced by convulsants.
Topics: Animals; Bicuculline; Brain; Convulsants; Glucose; Male; Penicillins; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Soman; Strychnine | 1985 |
Effects of glycine and GABA on the ganglion cels of the retina of the skate Raja erinacea.
Topics: Animals; Bicuculline; Fishes; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Picrotoxin; Retina; Retinal Ganglion Cells | 1985 |
Respiratory depression produced by injection of GABA into the fourth ventricle of the rabbit.
Topics: Animals; Bicuculline; Depression, Chemical; Diazepam; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Picrotoxin; Rabbits; Respiration | 1985 |
Actions of GABA and ethylenediamine on CA1 pyramidal neurones of the rat hippocampus.
Topics: Animals; Benzodiazepines; Bicuculline; Chlorides; Dendrites; Electric Conductivity; Ethylenediamines; gamma-Aminobutyric Acid; Hippocampus; Ion Exchange; Neurons; Osmolar Concentration; Picrotoxin; Potassium; Rats; Sodium | 1985 |
Stability of the amino acid content of nerve endings after administration of gamma-aminobutyrate agonists and antagonists.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Baclofen; Bicuculline; Brain Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mice; Muscimol; Nerve Endings; Picrotoxin; Synaptosomes | 1985 |
Development of sensitivity to GABA and glycine in cultured cerebellar neurons.
Topics: Action Potentials; Animals; Bicuculline; Cell Membrane; Cerebellum; Chick Embryo; Culture Techniques; Electric Conductivity; gamma-Aminobutyric Acid; Glycine; Picrotoxin; Strychnine | 1985 |
gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells.
Topics: Animals; Benzodiazepines; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Muscimol; Picrotoxin; Rats; Sulfur Radioisotopes; Temperature | 1985 |
Strychnine and L-allylglycine but not bicuculline and picrotoxin induce transsynaptic degeneration following transection of the inferior alveolar nerve in adult rats.
Topics: Allylglycine; Animals; Bicuculline; Glycine; Mandibular Nerve; Medulla Oblongata; Nerve Degeneration; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Synapses | 1985 |
The role of the gamma-aminobutyrate system in the interactions of cortical evoked potentials.
Topics: Acoustic Stimulation; Animals; Baclofen; Bicuculline; Cats; Cerebral Cortex; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin | 1985 |
Dynamics of gap junctions between horizontal cells in the goldfish retina.
Topics: Animals; Bicuculline; Freeze Fracturing; Goldfish; Intercellular Junctions; Microscopy, Electron; Neurons; Picrotoxin; Retina | 1985 |
Studies of the role of gamma-aminobutyric acid in the hypothalamic control of feed intake in sheep.
Topics: Animals; Bicuculline; Brain; Eating; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep | 1985 |
Antagonism of picrotoxin against the taming effect of carbamazepine on footshock induced fighting behavior in mice.
Topics: Aggression; Animals; Bicuculline; Carbamazepine; Diazepam; Electroshock; gamma-Aminobutyric Acid; Haloperidol; Lithium; Male; Mice; Pentylenetetrazole; Picrotoxin | 1985 |
The action of picrotoxin on the interspike interval in rat supraoptic neurones.
Topics: Action Potentials; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Neurons; Picrotoxin; Rats; Reaction Time; Supraoptic Nucleus | 1985 |
Effects of avermectin B1a and picrotoxin on striatal release of dopamine with reference to replacement of extracellular chloride with nitrate.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Chlorides; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Male; Nitrates; Picrotoxin; Rats; Rats, Inbred Strains; Tetrodotoxin; Verapamil | 1985 |
[Microiontophoretical application of GABA and L-glutamic-acid on neurons of the mammalian C.N.S (author's transl)].
Topics: Aminobutyrates; Animals; Bicuculline; Cats; Caudate Nucleus; Central Nervous System; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Neurons; Picrotoxin; Spinal Cord; Tetrodotoxin | 1974 |
Is gamma-aminobutyric acid the neurotransmitter of barnacle photoreceptors?
Topics: Animals; Bicuculline; Cell Membrane; gamma-Aminobutyric Acid; In Vitro Techniques; Photoreceptor Cells; Picrotoxin; Synaptic Membranes; Synaptic Transmission; Thoracica; Vision, Ocular | 1984 |
Avermectin modulation of GABA binding to membranes of rat brain, brine shrimp and a fungus, Mucor miehei.
Topics: Animals; Bicuculline; Brain; Chlorides; Decapoda; gamma-Aminobutyric Acid; Ivermectin; Kinetics; Lactones; Male; Mucor; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sodium | 1984 |
Barbiturates allosterically inhibit GABA antagonist and benzodiazepine inverse agonist binding.
Topics: Allosteric Regulation; Animals; Barbiturates; Benzodiazepines; Bicuculline; Binding, Competitive; Carbolines; Etazolate; GABA Antagonists; In Vitro Techniques; Kinetics; Picrotoxin; Rats; Receptors, GABA-A; Sesterterpenes; Stereoisomerism | 1984 |
Potentiation of GABAA-receptor-mediated responses by barbiturates in the guinea-pig ileum.
Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1984 |
GABAergic influence on the effects of elymoclavine on exploratory behaviour of rats in open field.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Ergolines; Exploratory Behavior; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Semicarbazides | 1984 |
[Effect of diazepam on various effects of morphine use in mice and rats].
Topics: Animals; Bicuculline; Diazepam; Drug Interactions; Etorphine; Male; Mice; Morphine; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Respiration; Synaptic Transmission | 1984 |
Modulation by picrotoxin and IPTBO of 3H-flunitrazepam binding to the GABA/benzodiazepine receptor complex of rat cerebellum.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Binding Sites; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cerebellum; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; Male; Membranes; Organophosphorus Compounds; Picrotoxin; Rats; Receptors, Drug; Receptors, GABA-A; Temperature | 1981 |
Septal driving of hippocampal theta rhythm: a role for gamma-aminobutyrate in the effects of minor tranquillizers?
Topics: Amobarbital; Animals; Anti-Anxiety Agents; Bicuculline; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Antagonism; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Picrotoxin; Rats; Septum Pellucidum | 1981 |
[Effect of GABA-negative preparations on the anxiolytic and sedative effects of diazepam].
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Picrotoxin; Rats | 1981 |
Effects of 1,3-bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione (FD 1) on the central nervous system: (2) Effects on nigro-striatal dopaminergic neurons.
Topics: alpha-Methyltyrosine; Aminooxyacetic Acid; Animals; Antineoplastic Agents; Bicuculline; Corpus Striatum; Dopamine; Fluorouracil; Male; Methyltyrosines; Neurons; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra; Tegafur; Tyrosine 3-Monooxygenase | 1981 |
The effects of anaesthetics on the uptake and release of amino acid neurotransmitters in thalamic slices.
Topics: Anesthetics; Animals; Aspartic Acid; Baclofen; Bicuculline; Calcium; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Methohexital; Neurotransmitter Agents; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Thalamus | 1982 |
Involvement of amino acids in periodic inhibitions of bulbar respiratory neurones.
Topics: Alanine; Amino Acids; Animals; Bicuculline; Cats; Glutamates; Glutamic Acid; Glycine; Kinetics; Medulla Oblongata; Methylene Blue; Muscimol; Neurons; Nipecotic Acids; Oxygen Consumption; Picrotoxin; Strychnine | 1982 |
Gabamimetic properties of anxiolytic drugs.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Caudate Nucleus; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Male; Movement; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Angiostrongylus cantonensis: paralysis due to avermectin B1a and ivermectin.
Topics: Adrenergic alpha-Antagonists; Alkaloids; Angiostrongylus; Animals; Anthelmintics; Bicuculline; Ivermectin; Lactones; Metastrongyloidea; Movement; Muscle Contraction; Phenylephrine; Physostigmine; Picrotoxin; Pyrantel; Quinolizines; Strychnine | 1984 |
[Effects of pentylenetetrazol on conflict behavior and interactions with anxiolytics in rats].
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains | 1983 |
The effects of GABA and benzodiazepine receptor antagonists on the anti-conflict actions of diazepam or ethanol.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Ethanol; Flumazenil; Male; Picrotoxin; Punishment; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
GABAB receptor-mediated inhibition of serotonin release in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Brain Chemistry; Cerebral Cortex; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Nipecotic Acids; Phentolamine; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Serotonin | 1984 |
A site for the potentiation of GABA-mediated responses by benzodiazepines.
Topics: Afferent Pathways; Animals; Bicuculline; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Ion Channels; Medulla Oblongata; Membrane Potentials; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
The effects of pentobarbital and related compounds on frog motoneurons.
Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission | 1980 |
GABA and muscimol inhibit the release of prolactin from dispersed rat anterior pituitary cells.
Topics: Animals; Bicuculline; Dopamine; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Distinction between the effects of barbiturates, benzodiazepines and phenytoin on responses to gamma-aminobutyric acid receptor activation and antagonism by bicuculline and picrotoxin.
Topics: Animals; Barbiturates; Benzodiazepines; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Muscimol; Phenytoin; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Pentobarbital enhances [3H]diazepam binding to soluble receptors at the benzodiazepine--GABA-receptor-ionophore complex.
Topics: Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; In Vitro Techniques; Ionophores; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1981 |
GABA and baclofen potentiate the K+-evoked release of methionine-enkephalin from rat striatal slices.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Corpus Striatum; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Picrotoxin; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Gaba induced excitatory responses in the guinea-pig small intestine are antagonized by bicuculline, picrotoxinin and chloride ion blockers.
Topics: Animals; Bicuculline; Chlorides; Diuretics; Female; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Myenteric Plexus; Picrotoxin; Sesterterpenes; Sulfonamides | 1981 |
Depressor effects of isoguvacine propyl ester and isoarecaidine propyl ester due to stimulation of central GABA receptors in the cat.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Female; Heart Rate; Hydrolysis; Infusions, Intra-Arterial; Isonicotinic Acids; Male; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Vertebral Artery | 1982 |
Repeated administration of subconvulsant doses of GABA antagonist drugs. I. Effect on seizure threshold (kindling).
Topics: Animals; Bicuculline; Electroshock; GABA Antagonists; Kindling, Neurologic; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Seizures | 1982 |
Classification of some GABA antagonists with regard to site of action and potency in slices of rat cuneate nucleus.
Topics: Animals; Bicuculline; Cyclic P-Oxides; Furosemide; GABA Antagonists; In Vitro Techniques; Medulla Oblongata; Organophosphorus Compounds; Pentylenetetrazole; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Strychnine; Tubocurarine | 1982 |
Antagonism of GABA-mediated responses by d-tubocurarine in hippocampal neurons.
Topics: Animals; Bicuculline; Culture Techniques; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Neural Inhibition; Neurons; Picrotoxin; Receptors, Adrenergic, beta; Seizures; Synapses; Synaptic Transmission; Tetrodotoxin; Tubocurarine | 1982 |
Interactions of agonists and antagonists with a novel type of GABA receptor.
Topics: Animals; Baclofen; Bicuculline; Corpus Striatum; GABA Antagonists; In Vitro Techniques; Isonicotinic Acids; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Sodium valproate enhances responses to GABA receptor activation only at high concentrations.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution; Valproic Acid | 1982 |
Blockade of forebrain gamma-aminobutyric acid (GABA) receptors and reflex activation of the cardiac vagus in anesthetized cats.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Female; Heart; Heart Rate; Injections, Intraventricular; Male; Muscimol; Neural Pathways; Phenylephrine; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Reflex; Spinal Cord; Vagus Nerve | 1982 |
Convulsant and anticonvulsant effects of opioids: relationship to GABA-mediated transmission.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Brain; Convulsants; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Morphine; Naloxone; Narcotics; Picrotoxin; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1982 |
Effects of GABAergic agonists and antagonists on various ethanol-induced behavioral changes.
Topics: Animals; Behavior, Animal; Bicuculline; Body Temperature Regulation; Dose-Response Relationship, Drug; Ethanol; Female; Motor Activity; Muridae; Muscimol; Oxazoles; Pentylenetetrazole; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Sleep Stages; Strychnine | 1982 |
[Effect of diazepam on reactivity of hippocampal neurons during blocking of GABA-ergic system].
Topics: Action Potentials; Animals; Bicuculline; Depression, Chemical; Diazepam; Drug Antagonism; Evoked Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Picrotoxin; Receptors, Neurotransmitter | 1982 |
Further characterization of the anorexic action of orally-administered THIP, a GABA-analogue, in the rat.
Topics: Administration, Oral; Animals; Bicuculline; Eating; gamma-Aminobutyric Acid; Isoxazoles; Male; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Strychnine | 1982 |
Presence of GABA receptors in rat oviduct.
Topics: Animals; Bicuculline; Binding, Competitive; Cyclic AMP; Fallopian Tubes; Female; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
The picrotoxin-like action of a convulsant benzodiazepine, Ro5-3663.
Topics: Animals; Benzodiazepinones; Bicuculline; Convulsants; In Vitro Techniques; Medulla Oblongata; Muscimol; Neurons; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments.
Topics: 3-Mercaptopropionic Acid; Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Brain; Cell Compartmentation; Cell Fractionation; Cerebellum; Drug Interactions; Female; gamma-Aminobutyric Acid; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Synaptosomes | 1983 |
gamma-Aminobutyric acid and cholinergic transmission in the guinea-pig ileum.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Synaptic Transmission; Tritium | 1983 |
Is the muscle relaxant effect of diazepam in spastic mutant rats mediated through GABA-independent benzodiazepine receptors?
Topics: Animals; Benzodiazepinones; Bicuculline; Diazepam; Electromyography; Female; Flumazenil; Male; Muscle Contraction; Muscle Relaxation; Picrotoxin; Rats; Rats, Mutant Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Biphasic effects of baclofen on phrenic motoneurons: possible involvement of two types of gamma-aminobutyric acid (GABA) receptors.
Topics: Animals; Baclofen; Bicuculline; Carbon Dioxide; Cats; Dose-Response Relationship, Drug; Female; Male; Motor Neurons; Phrenic Nerve; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
Large long-lasting potentiation in the dentate gyrus in vitro during blockade of inhibition.
Topics: Animals; Bicuculline; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Picrotoxin; Synapses; Synaptic Transmission | 1983 |
Two distinct interactions of barbiturates and chlormethiazole with the GABAA receptor complex in rat cuneate nucleus in vitro.
Topics: Animals; Barbiturates; Bicuculline; Chlormethiazole; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
Central gamma-aminobutyric acid involvement in blood pressure control.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Hypertension; Medulla Oblongata; Pentobarbital; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Respiration | 1984 |
GABA modulation of the defense reaction induced by brain electrical stimulation.
Topics: Animals; Benzodiazepines; Bicuculline; Blood Pressure; Chlordiazepoxide; Electric Stimulation; Escape Reaction; gamma-Aminobutyric Acid; Heart Rate; Male; Midazolam; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Respiration | 1983 |
Intranigral methionine sulfoximine induces turning behaviour in the rat.
Topics: Animals; Bicuculline; Hydroxydopamines; Male; Methionine Sulfoximine; Motor Activity; Oxidopamine; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Rotation | 1984 |
Saturable binding of 35S-t-butylbicyclophosphorothionate to the sites linked to the GABA receptor and the interaction with GABAergic agents.
Topics: Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sulfur Radioisotopes; Triazines | 1984 |
Triphasic locomotor response of a plant-parasitic nematode to avermectin: inhibition by the GABA antagonists bicuculline and picrotoxin.
Topics: Animals; Anthelmintics; Bicuculline; Ivermectin; Lactones; Motor Activity; Nematoda; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1984 |
GABA antagonists applied to the ventral surface of the medulla oblongata block the baroreceptor reflex.
Topics: Animals; Bicuculline; Blood Pressure; Brain Mapping; Cats; gamma-Aminobutyric Acid; Medulla Oblongata; Picrotoxin; Pressoreceptors; Reflex; Synaptic Transmission; Vasomotor System | 1984 |
Reversal of the anti-conflict action of valproate by various GABA and benzodiazepine antagonists.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Conflict, Psychological; Flumazenil; GABA Antagonists; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid | 1984 |
Fastigial influences on postural tonus as studied by kainate lesions and by local infusion of GABAergic drugs in the rat.
Topics: Animals; Bicuculline; Cerebellar Nuclei; Diazepam; Functional Laterality; gamma-Aminobutyric Acid; Kainic Acid; Male; Motor Activity; Muscle Tonus; Picrotoxin; Posture; Pyrrolidines; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1984 |
Inhibition of insulin hyperphagia by gamma aminobutyric acid antagonists in rats.
Topics: Animals; Bicuculline; Blood Glucose; Eating; GABA Antagonists; Hypothalamus; Insulin; Male; Picrotoxin; Rats; Rats, Inbred Strains | 1984 |
Effect of dihydroergotoxine on the susceptibility of rats to convulsions produced by different convulsant agents.
Topics: Animals; Bicuculline; Convulsants; Dihydroergotoxine; Drug Synergism; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Strychnine | 1983 |
Depolarizing responses to glycine, beta-alanine and muscimol in isolated optic nerve and cuneate nucleus.
Topics: Alanine; Animals; beta-Alanine; Bicuculline; Dose-Response Relationship, Drug; Glycine; Male; Medulla Oblongata; Muscimol; Optic Nerve; Oxazoles; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Time Factors | 1983 |
RO5-4864 inhibits the binding of [35S]t-butylbicyclophosphorothionate to rat brain membranes.
Topics: Androstanes; Animals; Azasteroids; Benzodiazepinones; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Male; Picrotoxin; Radioligand Assay; Rats | 1984 |
Electrophysiological effects of GABA on fish retinal horizontal cells are blocked by bicuculline but not by picrotoxin.
Topics: Aminobutyrates; Animals; beta-Alanine; Bicuculline; Cobalt; Fishes; GABA Antagonists; Membrane Potentials; Nipecotic Acids; Picrotoxin; Retina | 1984 |
Effect of prostaglandin synthetase inhibitors on experimentally induced convulsions in rats.
Topics: Animals; Anticonvulsants; Bicuculline; Cyclooxygenase Inhibitors; Electroshock; Female; Hindlimb; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1984 |
Effect of intrastriatal administration of cholinergic and GABAergic agonists on apomorphine-induced circling.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Drug Interactions; gamma-Aminobutyric Acid; Humans; Injections; Male; Muscimol; Parasympathomimetics; Picrotoxin; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Scopolamine; Stereotyped Behavior | 1984 |
Gamma-aminobutyric acid-induced contraction of the dog basilar artery.
Topics: Animals; Arachidonic Acids; Aspirin; Basilar Artery; Bicuculline; Dogs; Drug Interactions; Ethanol; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Indomethacin; Leukotrienes; Lipid Peroxides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Picrotoxin | 1984 |
Synergistic anticonvulsant effects of GABA-T inhibitors and glycine.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Drug Synergism; Ethanolamines; Glycine; Male; Mice; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Strychnine; Vigabatrin | 1984 |
The nature of the stimulatory action of gamma-aminobutyric acid in the isolated perfused dog adrenals.
Topics: Acetylcholine; Adrenal Glands; Animals; Atropine; Bicuculline; Calcium; Catecholamines; Cobalt; Dibucaine; Dogs; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Male; Picrotoxin; Tetrodotoxin; Verapamil | 1984 |
Prolactin and growth hormone secretion in chickens: stimulation by histamine and inhibition by gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Cells, Cultured; Chickens; Culture Media; Diphenhydramine; gamma-Aminobutyric Acid; Growth Hormone; Histamine; Hypothalamus; Picrotoxin; Pituitary Gland, Anterior; Prolactin | 1984 |
Evidence for a physiological role of GABA in the control of guinea-pig intestinal motility.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle, Smooth; Myenteric Plexus; Picrotoxin; Sesterterpenes; Tachyphylaxis | 1984 |
Miniature synaptic potentials recorded intracellularly from Purkinje cell dendrites in guinea pig cerebellar slices.
Topics: Amino Acids; Animals; Benzothiadiazines; Bicuculline; Cerebellum; Dendrites; Guinea Pigs; In Vitro Techniques; Interneurons; Magnesium; Membrane Potentials; Picrotoxin; Purkinje Cells; Strychnine; Synapses; Tetrodotoxin | 1984 |
Inhibitory modulation of cat somatosensory cortex: a pharmacological study.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cats; Evoked Potentials; Evoked Potentials, Somatosensory; Female; gamma-Aminobutyric Acid; Neural Inhibition; Picrotoxin; Somatosensory Cortex; Taurine | 1984 |
The role of the GABA mechanisms of the globus pallidus in mediating catalepsy, stereotypy and locomotor activity.
Topics: Animals; Bicuculline; Brain Mapping; Catalepsy; Drug Interactions; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1984 |
Anticonvulsant activity of the nipecotic acid ester, (+/-)-m-nitrophenyl-3-piperidinecarboxylate.
Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Nipecotic Acids; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1984 |
Convulsant-induced depression of amino acid responses in cultured mouse spinal neurones studied under voltage clamp.
Topics: Amino Acids; Animals; Bicuculline; Cells, Cultured; Convulsants; GABA Antagonists; Glycine; Membrane Potentials; Mice; Neurons; Pentylenetetrazole; Picrotoxin; Spinal Cord; Strychnine | 1983 |
Inhibitory mechanism in zebrafish optic tectum: visual response properties of tectal cells altered by picrotoxin and bicuculline.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials, Visual; Fishes; gamma-Aminobutyric Acid; Neural Inhibition; Optic Nerve; Pattern Recognition, Visual; Picrotoxin; Strychnine; Superior Colliculi; Synapses; Visual Pathways; Visual Perception | 1983 |
A short duration GABAergic inhibition in identified neostriatal medium spiny neurons: in vitro slice study.
Topics: Animals; Bicuculline; Corpus Striatum; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons; Penicillin G; Picrotoxin; Rats; Synapses | 1983 |
Dissociation between epileptic seizures induced by convulsant drugs and alteration in the concentrations of pyridoxal phosphate in rat brain regions.
Topics: 3-Mercaptopropionic Acid; Allylglycine; Animals; Bicuculline; Brain; Convulsants; Epilepsy; Male; Picrotoxin; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Strychnine | 1983 |
Generation of respiratory activity by the lamprey brain exposed to picrotoxin and strychnine, and weak synaptic inhibition in motoneurons.
Topics: Animals; Bicuculline; Brain; Fishes; gamma-Aminobutyric Acid; Glycine; Lampreys; Motor Neurons; Neural Inhibition; Neurons; Periodicity; Picrotoxin; Respiration; Respiratory System; Strychnine; Synapses | 1983 |
Morphine potentiates seizures induced by GABA antagonists and attenuates seizures induced by electroshock in the rat.
Topics: Animals; Bicuculline; Drug Synergism; Electroshock; GABA Antagonists; Isoniazid; Male; Morphine; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1983 |
Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in vitro.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Growth Hormone; In Vitro Techniques; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1984 |
Experimental hemichorea/hemiballismus in the monkey. Studies on the intracerebral site of action in a drug-induced dyskinesia.
Topics: Animals; Bicuculline; Brain Diseases; Brain Mapping; Chorea; Dyskinesia, Drug-Induced; Female; Globus Pallidus; Injections; Macaca; Male; Movement Disorders; Muscimol; Papio; Picrotoxin; Thalamic Nuclei | 1984 |
Actions of gamma-aminobutyric acid on neurones of guinea-pig myenteric plexus.
Topics: Acetylcholine; Alanine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Myenteric Plexus; Neural Conduction; Neuromuscular Depolarizing Agents; Neurons; Nipecotic Acids; Picrotoxin; Proline; Tetrodotoxin | 1984 |
The identification and some functions of GABAergic neurons in the distal catfish retina.
Topics: Adaptation, Ocular; Animals; Bicuculline; Fishes; gamma-Aminobutyric Acid; Neurons; Photoreceptor Cells; Picrotoxin; Potassium; Retina | 1984 |
Amino acid antagonists do not block the depolarizing effects of potassium ions on frog primary afferents.
Topics: Animals; Anura; beta-Alanine; Bicuculline; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neurons, Afferent; Picrotoxin; Potassium; Rana pipiens; Strychnine | 1980 |
GABA conductance of chick spinal cord and dorsal root ganglion neurons in cell culture.
Topics: Amino Acids; Animals; beta-Alanine; Bicuculline; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Iontophoresis; Neurons; Picrotoxin; Spinal Cord; Strychnine; Taurine | 1981 |
Repeated administration of subconvulsant doses of GABA antagonist drugs. II. Effect on monoamine-mediated behaviour.
Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; GABA Antagonists; Humans; Kindling, Neurologic; Male; Methamphetamine; Motor Activity; Pentylenetetrazole; Picrotoxin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Stereotyped Behavior | 1982 |
Effects of benzodiazepines on single unit activity in the substantia nigra pars reticulata.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Caffeine; Diazepam; Dose-Response Relationship, Drug; Electric Conductivity; Flumazenil; Flurazepam; Male; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Substantia Nigra; Theophylline | 1982 |
GABAergic influences on defensive fighting in rats.
Topics: Aggression; Aminocaproates; Animals; Baclofen; Bicuculline; Electroshock; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Valproic Acid; Vigabatrin | 1982 |
Strychnine blocks binaural inhibition in lateral superior olivary neurons.
Topics: Acoustic Stimulation; Animals; Bicuculline; Chinchilla; Functional Laterality; gamma-Aminobutyric Acid; Glycine; Neurons; Olivary Nucleus; Picrotoxin; Strychnine | 1983 |
GABAergic drugs, morphine and morphine tolerance: a study in relation to nociception and gastrointestinal transit in mice.
Topics: Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Bicuculline; Cyclohexanecarboxylic Acids; Digestion; Digestive System; Digestive System Physiological Phenomena; Drug Tolerance; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Naloxone; Nociceptors; Oxazoles; Picrotoxin | 1983 |
gamma-Aminobutyric acid antagonists decrease junctional communication between L-horizontal cells of the retina.
Topics: Animals; Bicuculline; Cell Communication; GABA Antagonists; Intercellular Junctions; Isoquinolines; Picrotoxin; Retina; Turtles; Visual Fields | 1982 |
Anisatin, a potent GABA antagonist, isolated from Illicium anisatum.
Topics: Afferent Pathways; Animals; Bicuculline; Brain; Dose-Response Relationship, Drug; Evoked Potentials; Ganglia, Spinal; Lactones; Picrotoxin; Plants, Toxic; Rana catesbeiana; Rats; Sesquiterpenes; Spinal Cord; Spiro Compounds; Synaptic Membranes | 1981 |
Synaptic and non-synaptic components of the dorsal horn potential in isolated hamster spinal cord.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cricetinae; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Spinal Cord; Synapses; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1982 |
Antagonism of gamma-aminobutyric acid and muscimol by picrotoxin, bicuculline, strychnine, bemegride, leptazol, D-tubocurarine and theophylline in the isolated olfactory cortex.
Topics: Animals; Bicuculline; GABA Antagonists; Guinea Pigs; In Vitro Techniques; Muscimol; Olfactory Bulb; Oxazoles; Pentylenetetrazole; Picrotoxin; Strychnine; Theophylline; Tubocurarine | 1982 |
Further characterization of the behavioral despair test in mice: positive effects of convulsants.
Topics: Animals; Antidepressive Agents; Bicuculline; Brain; Convulsants; Dextroamphetamine; Escape Reaction; Male; Mice; Motivation; Motor Activity; Muridae; Picrotoxin; Seizures; Sleep, REM; Strychnine | 1982 |
On the involvement of GABA in the analgesia produced by baclofen, muscimol and morphine.
Topics: 4-Aminobutyrate Transaminase; Analgesia; Analgesics; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Naloxone; Picrotoxin; Transaminases | 1982 |
Does homocarnosine mediate the dyskinetic movements induced by gaba-transaminase inhibitors.
Topics: 4-Aminobutyrate Transaminase; Animals; Bicuculline; Carnosine; Dipeptides; Dyskinesia, Drug-Induced; Injections, Intraventricular; Picrotoxin; Rats | 1982 |
Gamma-aminobutyric acid can both inhibit and facilitate dopamine release in the caudate nucleus of the rabbit.
Topics: Animals; Bicuculline; Caudate Nucleus; Dopamine; Drug Interactions; Electric Stimulation; Female; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Picrotoxin; Rabbits; Synaptosomes | 1982 |
In vivo modulations by GABA-related drugs of met-enkephalin release in basal ganglia of the cat brain.
Topics: Animals; Bicuculline; Cats; Caudate Nucleus; Diazepam; Drug Interactions; Enkephalin, Methionine; Female; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Picrotoxin | 1982 |
A tonic gamma-aminobutyric acid-mediated inhibition of cholinergic amacrine cells in rabbit retina.
Topics: Acetylcholine; Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Photic Stimulation; Picrotoxin; Rabbits; Receptors, Cholinergic; Retina | 1982 |
High-affinity choline uptake in the hippocampus: its relationship to the physiological state produced by administration of barbiturates and other treatments.
Topics: Animals; Barbiturates; Bicuculline; Choline; Convulsants; Hippocampus; Kinetics; Male; Mice; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Septum Pellucidum; Synaptosomes | 1982 |
[Presynaptic component in the mechanism of fenibut action].
Topics: Animals; Baclofen; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Synaptosomes | 1982 |
On the mechanism by which dopamine inhibits prolactin release in the anterior pituitary.
Topics: Animals; Bicuculline; Chlorpromazine; Depression, Chemical; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Male; Mice; Mice, Inbred C57BL; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Sesterterpenes | 1982 |
GABA-mediated negative feedback and color opponency in carp retina.
Topics: Animals; Bicuculline; Carps; Color Perception; Electrophysiology; Feedback; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Perfusion; Photoreceptor Cells; Picrotoxin; Retina; Synapses | 1982 |
Anticonvulsant effects of muscimol.
Topics: Animals; Bicuculline; GABA Antagonists; Muscimol; Neurons; Oxazoles; Penicillins; Picrotoxin; Rats; Receptors, Drug; Seizures; Strychnine | 1980 |
Rotation induced by intranigral injections of GABA agonists and antagonists: zone-specific effects.
Topics: Animals; Bicuculline; GABA Antagonists; Humans; Hydroxydopamines; Male; Muscimol; Oxazoles; Picrotoxin; Rats; Rotation; Stereotyped Behavior; Substantia Nigra | 1980 |
[GABA-ergic correlates of aggression and intraspecies sociability of mice subjected to isolation].
Topics: Aggression; Alkynes; Aminocaproates; Animals; Bicuculline; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin; Semicarbazides; Social Behavior; Social Isolation | 1981 |
Further studies of the chemical sensitivity of the oscillatory potentials of the electroretinogram (ERG) I. GABA- and glycine antagonists.
Topics: Action Potentials; Animals; Bicuculline; Culture Media; Culture Techniques; Depression, Chemical; Electroretinography; GABA Antagonists; Glycine; Necturus maculosus; Picrotoxin; Retina; Strychnine | 1980 |
SL 75 102 as a gama-aminobutyric acid agonist: experiments on dorsal root ganglion neurones in vitro.
Topics: Animals; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Guinea Pigs; In Vitro Techniques; Neurons; Picrotoxin | 1981 |
Sensitivity of identified medial hypothalamic neurons to GABA, glycine and related amino acids; influence of bicuculline, picrotoxin and strychnine on synaptic inhibition.
Topics: Amino Acids; Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glycine; Hypothalamus; Hypothalamus, Middle; Male; Neural Inhibition; Neurons; Picrotoxin; Rats; Strychnine; Synapses | 1981 |
Effect of GABA agonist and antagonists on cardiovascular and sympathetic responses in SHR and WKY rats.
Topics: Animals; Bicuculline; Cardiovascular Physiological Phenomena; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Rats; Sympathetic Nervous System | 1981 |
GABA antagonists enhance dopamine turnover in the rat retina in vivo.
Topics: Adaptation, Physiological; alpha-Methyltyrosine; Animals; Atropine; Bicuculline; Darkness; Dopamine; GABA Antagonists; Male; Methyltyrosines; Picrotoxin; Rats; Retina | 1981 |
GABA-mediated synaptic potentials in chick spinal cord and sensory neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Chick Embryo; Chlordiazepoxide; Electrophysiology; gamma-Aminobutyric Acid; Ganglia, Spinal; Neurons; Picrotoxin; Sensory Receptor Cells; Spinal Cord; Strychnine; Synapses; Time Factors | 1981 |
Physiological and pharmacological basis of GABA and glycine action on neurons of mudpuppy retina. II. Amacrine and ganglion cells.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Glycine; Interneurons; Necturus; Neurons; Picrotoxin; Retina; Strychnine | 1981 |
Physiological and pharmacological basis of GABA and glycine action on neurons of mudpuppy retina. III. Amacrine-mediated inhibitory influences on ganglion cell receptive-field organization: a model.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Glycine; Models, Neurological; Necturus; Neural Inhibition; Neurons; Picrotoxin; Retina; Strychnine | 1981 |
Two kinds of recurrent inhibition of cat spinal alpha-motoneurones as differentiated pharmacologically.
Topics: Animals; Bicuculline; Cats; Evoked Potentials; GABA Antagonists; Motor Neurons; Neural Inhibition; Picrotoxin; Spinal Nerve Roots; Strychnine | 1981 |
GABA-antagonists and spatial summation in Y-type cat retinal ganglion cells.
Topics: Animals; Bicuculline; Cats; Dark Adaptation; GABA Antagonists; Neurons; Picrotoxin; Retina; Space Perception | 1981 |
Effects of GABA on electrical properties of cultured rat pituitary tumor cells: an intracellular recording study.
Topics: Action Potentials; Animals; Bicuculline; Clone Cells; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Picrotoxin; Pituitary Neoplasms; Prolactin; Rats | 1981 |
Direct action of pentobarbitone in potentiating the responses to GABA of rat dorsal root ganglion neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons; Pentobarbital; Picrotoxin; Rats | 1981 |
Behavioural effects of GABA-agonists and antagonists infused in the mesencephalic reticular formation - deep layers of superior colliculus.
Topics: Animals; Behavior, Animal; Bicuculline; Dominance, Cerebral; gamma-Aminobutyric Acid; Mesencephalon; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Reticular Formation; Seizures; Superior Colliculi | 1981 |
Possible involvement of gamma-aminobutyric acid in growth hormone release induced by a Met5-enkephalin analog in conscious rats.
Topics: Animals; Bicuculline; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalins; gamma-Aminobutyric Acid; Growth Hormone; Hormones; Kinetics; Male; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains | 1981 |
Effects of 5-hydroxytryptamine on central neurones antagonized by bicuculline and picrotoxin.
Topics: Animals; Bicuculline; Brain; Cerebral Cortex; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Neurons; Picrotoxin; Rats; Serotonin; Serotonin Antagonists | 1981 |
Pharmacological investigation of gamma aminobutyric acid (GABA) and the development of amygdala-kindled seizures in the rat.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Aminocaproates; Amygdala; Animals; Bicuculline; gamma-Aminobutyric Acid; Imidazoles; Kindling, Neurologic; Male; Pentobarbital; Picrotoxin; Rats; Seizures; Vigabatrin | 1981 |
Antagonism by penicillin of gamma-aminobutyric acid depolarizations at presynaptic sites in rat olfactory cortex and cuneate nucleus in vitro.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Medulla Oblongata; Muscimol; Penicillin G; Penicillins; Picrotoxin; Rats; Synapses | 1980 |
Evidence that bicuculline and picrotoxin act at separate sites to antagonize gamma-aminobutyric acid in rat cuneate nucleus.
Topics: Action Potentials; Animals; Bicuculline; Drug Interactions; GABA Antagonists; In Vitro Techniques; Kinetics; Medulla Oblongata; Muscimol; Picrotoxin; Rats | 1980 |
Physiological identification of GABA as the inhibitory transmitter for mammalian cortical neurons in cell culture.
Topics: Animals; Bicuculline; Cerebral Cortex; Culture Techniques; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Neurons; Picrotoxin; Rats; Strychnine; Synapses | 1980 |
Effects of anticonvulsants and glutamate antagonists on the convulsive action of kainic acid.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bemegride; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; Pentylenetetrazole; Picrotoxin; Pyrrolidines; Seizures | 1980 |
Pharmacological blockade of the globus palidus-induced inhibitory response of subthalamic cells in the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glycine; Male; Muscimol; Neurons; Picrotoxin; Rats; Strychnine; Synapses; Thalamus | 1980 |
Effect of GABA analogues on blood pressure and central GABA metabolism in the rat.
Topics: 3-Mercaptopropionic Acid; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Blood Pressure; Brain; Dopamine; gamma-Aminobutyric Acid; Heart Rate; Hydroxybutyrates; Male; Muscimol; Picrotoxin; Rats; Sodium Oxybate | 1980 |
Inhibition of depressor cardiovascular reflexes by a derivative of gamma-aminobutyric acid (GABA) and by general anesthetics with suspected GABA-mimetic effects.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Blood Pressure; Cats; Chloralose; Female; gamma-Aminobutyric Acid; Male; Methohexital; Picrotoxin; Reflex; Sympathetic Nervous System; Urethane | 1980 |
Convulsants antagonise inhibition in the olfactory cortex slice.
Topics: Animals; Barbiturates; Bicuculline; Cerebral Cortex; Convulsants; Evoked Potentials; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Membrane Potentials; Neural Conduction; Olfactory Pathways; Picrotoxin | 1980 |
Two distinct inhibitory responses of cultured, mammalian spinal neurones to ibotenic acid.
Topics: Animals; Bicuculline; Cells, Cultured; Female; Ibotenic Acid; Membrane Potentials; Mice; Neurons; Oxazoles; Picrotoxin; Pregnancy; Spinal Cord | 1980 |
Evidence for a tonic GABAergic control of serotonin neurons in the median raphe nucleus.
Topics: Animals; Bicuculline; Brain Stem; Diazepam; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Picrotoxin; Probenecid; Raphe Nuclei; Rats; Serotonin | 1981 |
Subunit composition determines picrotoxin and bicuculline sensitivity of Drosophila gamma-aminobutyric acid receptors.
Topics: Animals; Base Sequence; Bicuculline; Drosophila; Female; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Molecular Sequence Data; Picrotoxin; Receptors, GABA; Spodoptera; Xenopus | 1995 |
In vitro effects of VD-99-11 on Angiostrongylus cantonensis and isolated frog rectus.
Topics: Angiostrongylus cantonensis; Animals; Antinematodal Agents; Bicuculline; Female; Guanidine; Guanidines; Hemicholinium 3; In Vitro Techniques; Macrolides; Muscle Contraction; Muscle, Skeletal; Paralysis; Phentolamine; Physostigmine; Picrotoxin; Pyrantel; Rats; Rats, Wistar; Strychnine; Sympatholytics | 1995 |
Effects of barbital or diazepam withdrawal on seizure thresholds to bicuculline, picrotoxin and flurazepam.
Topics: Animals; Barbital; Bicuculline; Convulsants; Diazepam; Flurazepam; Male; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Substance Withdrawal Syndrome | 1995 |
GABAergic activity of quisqualamine and homoquisqualamine in hemisected spinal cord in vitro preparation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Bicuculline; Decarboxylation; Evoked Potentials; GABA Agonists; Magnesium; Muscimol; Picrotoxin; Quisqualic Acid; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1994 |
Differential pharmacology of GABAA and GABAC receptors on rat retinal bipolar cells.
Topics: Animals; Bicuculline; Binding Sites; Cells, Cultured; Chickens; Chloride Channels; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; GABA-A Receptor Antagonists; Hexachlorocyclohexane; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Retina; Sesterterpenes; Signal Transduction | 1994 |
[The modulating effect of an optical sensory input on the excitability of the motor center in insects].
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Motor Neurons; Ocular Physiological Phenomena; Periplaneta; Photic Stimulation; Picrotoxin; Sensation; Statistics, Nonparametric | 1994 |
Decreased predator avoidance in parasitized mice: neuromodulatory correlates.
Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Cats; Coccidiosis; Dizocilpine Maleate; Eimeria; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; N-Methylaspartate; Naloxone; Odorants; Picrotoxin; Predatory Behavior; Receptors, GABA-A | 1995 |
A single point mutation decreases picrotoxinin sensitivity of the human GABA receptor rho 1 subunit.
Topics: Base Sequence; Bicuculline; Cell Line; Humans; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Point Mutation; Proline; Protein Structure, Tertiary; Receptors, GABA; Serine; Sesterterpenes | 1995 |
Involvement of benzodiazepine/GABA-A receptor complex in ethanol-induced state-dependent learning in rats.
Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Bicuculline; Diazepam; Ethanol; Evaluation Studies as Topic; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A | 1995 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Neonatal caffeine exposure and seizure susceptibility in adult rats.
Topics: Animals; Animals, Newborn; Bicuculline; Brain; Caffeine; Female; Kainic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Receptors, Purinergic P1; Seizures; Sex Factors; Strychnine | 1995 |
Post-training injection of GABAergic antagonists into the striatum produces retrograde amnesia.
Topics: Amnesia, Retrograde; Animals; Avoidance Learning; Behavior, Animal; Bicuculline; Corpus Striatum; Male; Picrotoxin; Rats; Rats, Wistar | 1995 |
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine | 1993 |
Counteraction of the rapid tolerance to 8-OH-DPAT-induced corticosterone secretion in rats by activation of the GABAA receptor-chloride channel complex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepines; Bicuculline; Chloride Channels; Chlormethiazole; Corticosterone; Drug Tolerance; Ion Channels; Male; Membrane Proteins; Muscimol; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1993 |
Strychnine-sensitive glycine receptors in cultured primary neurons from rat neocortex.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebral Cortex; Chloride Channels; Electrophysiology; Female; gamma-Aminobutyric Acid; Glycine; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Picrotoxin; Pregnancy; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Neurotransmitter; Strychnine | 1993 |
Enhancement of gamma-aminobutyric acid-activated chloride channel currents by lanthanides in rat dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Metals, Rare Earth; Neurons; Penicillins; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Terbium; Zinc | 1993 |
Multiple GABA receptor subtypes mediate inhibition of calcium influx at rat retinal bipolar cell terminals.
Topics: Animals; Axons; Baclofen; Bicuculline; Calcium; Cells, Cultured; gamma-Aminobutyric Acid; Nerve Endings; Organophosphorus Compounds; Picrotoxin; Potassium; Propylamines; Rats; Receptors, GABA; Receptors, GABA-A; Retina | 1995 |
GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Astrocytes; Bicuculline; Brain; Calcium; Calcium Channels; Carbolines; Cell Separation; Chlorides; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Gene Expression; Glial Fibrillary Acidic Protein; Hippocampus; Immunoblotting; In Vitro Techniques; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscimol; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Muscimol; Parasympatholytics; Picrotoxin; Rats; Rats, Sprague-Dawley; Social Behavior | 1995 |
Effect of Leu-enkephalin on the memory reactivation produced by blockade of the benzodiazepine/GABA-chloride ionophore receptor complex.
Topics: Analysis of Variance; Animals; Avoidance Learning; Bicuculline; Enkephalin, Leucine; Flumazenil; GABA-A Receptor Antagonists; Male; Memory Disorders; Mice; Mice, Inbred BALB C; Picrotoxin; Receptors, Opioid, delta | 1995 |
[Involvement of GABAergic and NMDA systems in drug-induced convulsions in mice].
Topics: Animals; Anticonvulsants; Bicuculline; Calcium Channels; Chloride Channels; Male; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Picrotoxin; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Seizures | 1995 |
gamma-Aminobutyric acid type A receptor antagonists picrotoxin and bicuculline alter acetylcholine channel kinetics in cultured embryonic rat skeletal muscle.
Topics: Animals; Bicuculline; Cells, Cultured; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Kinetics; Muscle, Skeletal; Picrotoxin; Rats; Receptors, Cholinergic | 1994 |
Quantitative autoradiography of 4'-ethynyl-4-n-[2,3-3H2]propylbicycloorthobenzoate binding to the GABAA receptor complex.
Topics: Adult; Aged; Aged, 80 and over; Animals; Autoradiography; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; GABA Agonists; Humans; Isonicotinic Acids; Male; Middle Aged; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Species Specificity | 1994 |
Spread of epileptiform activity in the immature rat neocortex studied with voltage-sensitive dyes and laser scanning microscopy.
Topics: Age Factors; Animals; Bicuculline; Culture Techniques; Epilepsy; Frontal Lobe; Membrane Potentials; Microscopy; Picrotoxin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1994 |
Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Propofol; Receptors, GABA-A; Strychnine; Xenopus laevis | 1995 |
Strain-dependent effects of post-training GABA receptor agonists and antagonists on memory storage in mice.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Muscimol; Organophosphorus Compounds; Picrotoxin; Species Specificity | 1993 |
GABAA receptor stimulation enhances NMDA-induced Ca2+ influx in mouse cerebral cortical neurons in primary culture.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebral Cortex; Chloride Channels; Dizocilpine Maleate; Dose-Response Relationship, Drug; GABA Agonists; Isonicotinic Acids; Mice; Muscimol; N-Methylaspartate; Neurons; Picrotoxin; Potassium; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1994 |
Local inhibitory synaptic inputs to neurones of the paraventricular nucleus in slices of rat hypothalamus.
Topics: Animals; Bicuculline; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Neurons; Paraventricular Hypothalamic Nucleus; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical; Synapses | 1993 |
GABAA and glutamate receptor involvement in dendrodendritic synaptic interactions from salamander olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Ambystoma; Animals; Bicuculline; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Histocytochemistry; Image Processing, Computer-Assisted; In Vitro Techniques; Interneurons; Ion Channel Gating; Neural Pathways; Olfactory Bulb; Olfactory Nerve; Picrotoxin; Quinoxalines; Receptors, GABA-A; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
The electrophysiological effects of endogenous GABA in the guinea-pig inferior mesenteric ganglion.
Topics: Acetylcholine; Afferent Pathways; Animals; Bicuculline; Colon; Diazepam; Efferent Pathways; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Mesentery; Physical Stimulation; Picrotoxin; Receptors, GABA | 1993 |
Morphological correlates of altered neuronal activity in organotypic cerebellar cultures chronically exposed to anti-GABA agents.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cerebellum; Electrophysiology; GABA Antagonists; Mice; Mice, Inbred Strains; Microscopy, Electron; Neural Inhibition; Neurons; Organ Culture Techniques; Picrotoxin; Quinoxalines; Synapses; Time Factors | 1994 |
[The effect of picrotoxin and bicuculline on desensitization of the GABA receptor/Cl-ionophore complex].
Topics: Animals; Bicuculline; Biological Transport; Chlorides; GABA Antagonists; Ionophores; Male; Picrotoxin; Rats | 1994 |
GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?
Topics: Acetylcarnitine; Acetylcholine; Action Potentials; Animals; Bicuculline; Chloride Channels; Clonazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Potassium Chloride; Pregnanolone; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Substrate Specificity; Tetrodotoxin; Zinc | 1994 |
Control of impulse conduction in long range branches of afferents by increases and decreases of primary afferent depolarization in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Axons; Bicuculline; Decerebrate State; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neural Conduction; Neurons, Afferent; Picrotoxin; Rats; Rats, Wistar; Spinal Nerve Roots | 1994 |
Excitatory action of gamma-aminobutyric acid (GABA) on crustacean neurosecretory cells.
Topics: Action Potentials; Animals; Astacoidea; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Eye; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Microinjections; Neurites; Neurosecretory Systems; Picrotoxin; Synapses | 1994 |
A novel gamma-aminobutyric acid receptor subunit (rho 2) cloned from human retina forms bicuculline-insensitive homooligomeric receptors in Xenopus oocytes.
Topics: Animals; Bicuculline; Chemical Phenomena; Chemistry; Chloride Channels; Cloning, Molecular; Dose-Response Relationship, Drug; Electrophysiology; Female; gamma-Aminobutyric Acid; Humans; Muscimol; Oocytes; Picrotoxin; Receptors, GABA; Retina; Xenopus | 1994 |
Presynaptic actions of GABA and baclofen in CA1 region of the guinea-pig hippocampus in vitro.
Topics: Animals; Baclofen; Bicuculline; Calcium; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Organophosphorus Compounds; Picrotoxin; Receptors, Presynaptic; Sesterterpenes; Tetrodotoxin | 1994 |
Fast presynaptic GABAA receptor-mediated Cl- conductance in cultured rat hippocampal neurones.
Topics: Animals; Bicuculline; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lidocaine; Neurons; Picrotoxin; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Presynaptic; Synapses; Synaptic Transmission; Tetrodotoxin | 1994 |
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis | 1994 |
[Effect of preliminary administration of phenobarbital on the toxicity of GABA-lytics in mice].
Topics: 3-Mercaptopropionic Acid; Animals; Antidotes; Barbiturates; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Phenobarbital; Picrotoxin; Time Factors | 1993 |
Effects of endothelin-1 (ET-1) and endothelin-3 (ET-3) on convulsive seizures.
Topics: Animals; Anticonvulsants; Bicuculline; Endothelins; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Pentylenetetrazole; Picrotoxin; Seizures; Strychnine | 1994 |
Release of endogenous glutamic and aspartic acids from cerebrocortex synaptosomes and its modulation through activation of a gamma-aminobutyric acidB (GABAB) receptor subtype.
Topics: Animals; Aspartic Acid; Baclofen; Bicuculline; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Male; Organophosphorus Compounds; Picrotoxin; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1993 |
Synaptic activation in guinea-pig dentate area: dependence on the stimulation site.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Carbachol; Electric Stimulation; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Microelectrodes; Nerve Fibers; Picrotoxin; Potassium Chloride; Quinoxalines; Receptors, GABA-A; Receptors, Glutamate; Synapses | 1993 |
CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium Channels; Quinoxalines; Synapses | 1993 |
Magnesium valproate attenuates hyperactivity induced by dexamphetamine-chlordiazepoxide mixture in rodents.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Bicuculline; Chlordiazepoxide; Dextroamphetamine; Drug Interactions; Female; GABA-A Receptor Antagonists; Isoniazid; Mice; Motor Activity; Picrotoxin; Rats; Rats, Sprague-Dawley; Valproic Acid | 1993 |
Interaction of beta-endorphin and GABAergic drugs in the regulation of memory storage.
Topics: Animals; Avoidance Learning; beta-Endorphin; Bicuculline; Conditioning, Classical; Dose-Response Relationship, Drug; Electroshock; Fear; Injections, Intraperitoneal; Male; Mice; Muscimol; Naloxone; Naltrexone; Picrotoxin; Reaction Time; Receptors, GABA; Receptors, Opioid; Retention, Psychology | 1993 |
[The effect of triorthocresyl phosphate on the toxicity of GABA-lytics for mice].
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Ester Hydrolases; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Male; Mice; Picrotoxin; Synaptic Membranes; Tritolyl Phosphates | 1993 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
GABA transporters and GABAC-like receptors on catfish cone- but not rod-driven horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Chloride Channels; Crotonates; Electrophysiology; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ictaluridae; Kainic Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Muscimol; Organic Anion Transporters; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Stereoisomerism; Time Factors | 1994 |
GABA inhibition of lateral hypothalamic neurons: role of reticular thalamic afferents.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Luteinizing Hormone; Male; Neural Inhibition; Neurons; Neurons, Afferent; Picrotoxin; Rats; Rats, Inbred Strains; Reticular Formation; Thalamus | 1994 |
Circling behaviour induced by activation of GABAA receptors in the subthalamic nucleus.
Topics: Animals; Bicuculline; Cats; Female; Male; Mesencephalon; Microinjections; Muscimol; Picrotoxin; Receptors, GABA-A; Stereotyped Behavior; Thalamic Nuclei | 1993 |
Biphasic GABA-A receptor-mediated effect on the spontaneous activity of the circular layer in cat terminal ileum.
Topics: Animals; Atropine; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1993 |
Interacting presynaptic kappa-opioid and GABAA receptors modulate dopamine release from rat striatal synaptosomes.
Topics: Analysis of Variance; Animals; Benzeneacetamides; Bicuculline; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Kinetics; Male; Naltrexone; Narcotics; Oligopeptides; Picrotoxin; Potassium; Pyrrolidines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, kappa; Synaptosomes | 1993 |
Dual action of GABAA receptors on the secretory process of melanotrophs of Xenopus laevis.
Topics: alpha-MSH; Animals; Bicuculline; Cyclic AMP; Isonicotinic Acids; Picrotoxin; Receptors, GABA-A; Xenopus laevis | 1993 |
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cimetidine; Diazepam; Female; Mice; Muscimol; Phenobarbital; Phenytoin; Picrotoxin; Receptors, GABA; Seizures; Strychnine | 1993 |
GABAergic control of odour-induced activity in the frog olfactory bulb: possible GABAergic modulation of granule cell inhibitory action.
Topics: Action Potentials; Animals; Anisoles; Bicuculline; Camphor; Cyclohexenes; Efferent Pathways; Feedback; gamma-Aminobutyric Acid; Limonene; Odorants; Olfactory Bulb; Pentanols; Picrotoxin; Rana ridibunda; Receptors, GABA; Terpenes | 1993 |
Reconstitution of purified GABAA receptors: ligand binding and chloride transporting properties.
Topics: Animals; Bicuculline; Biological Transport; Brain Chemistry; Cattle; Chlorides; Chromatography, Affinity; Dose-Response Relationship, Drug; Flow Injection Analysis; Flunitrazepam; Ligands; Liposomes; Membrane Proteins; Muscimol; Picrotoxin; Quinolinium Compounds; Receptors, GABA-A | 1994 |
[The effect of 3-mercaptopropionic acid on the toxicity of GABA-lytics for mice].
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Ligands; Male; Mice; Picrotoxin; Synaptic Membranes; Time Factors | 1993 |
Effects of serotonin and the 5-HT2/1C receptor agonist DOI on neurons of the cerebellar dentate/interpositus nuclei: possible involvement of a GABAergic interneuron.
Topics: Action Potentials; Amphetamines; Animals; Bicuculline; Cerebellar Nuclei; gamma-Aminobutyric Acid; Interneurons; Iontophoresis; Male; Neurons, Afferent; Picrotoxin; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin; Serotonin Receptor Agonists | 1993 |
The neuronal mechanism underlying parkinsonism and dyskinesia, and differential roles of the putamen and caudate nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Bicuculline; Cats; Caudate Nucleus; Globus Pallidus; Injections, Subcutaneous; Macaca; Motor Skills; Movement Disorders; Neural Pathways; Neurons; Parkinson Disease, Secondary; Picrotoxin; Putamen; Rats; Rats, Wistar; Synaptic Transmission | 1993 |
GABA-activated chloride channels in secretory nerve endings.
Topics: Animals; Bicuculline; Chlordiazepoxide; Chloride Channels; Chlorides; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Membrane Proteins; Muscimol; Nerve Endings; Picrotoxin; Pituitary Gland, Posterior; Rats; Receptors, GABA-A | 1993 |
Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.
Topics: Action Potentials; Animals; Bicuculline; Culture Techniques; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Pentobarbital; Picrotoxin; Rats; Synapses; Synaptic Transmission; Zinc | 1993 |
Serotonin inhibits induction of long-term potentiation at commissural synapses in hippocampus.
Topics: Animals; Bicuculline; Electrophysiology; GABA Antagonists; Hippocampus; Male; Methysergide; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Serotonin; Synapses; Synaptic Transmission | 1993 |
Interaction between benzodiazepine and GABA-A receptors in state-dependent learning.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values | 1993 |
Antagonist inhibition of GABAA-mediated chloride uptake is atypical in nigrocollicular areas.
Topics: Animals; Bicuculline; Brain; Chlorides; Chlorine; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inferior Colliculi; Ionophores; Kinetics; Male; Picrotoxin; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stimulation, Chemical; Substantia Nigra; Superior Colliculi | 1993 |
Inhibitory effect of diazepam on the activity of the hypothalamic-pituitary-adrenal axis in female rats.
Topics: Adrenocorticotropic Hormone; Animals; Bicuculline; Corticosterone; Depression, Chemical; Diazepam; Female; Flumazenil; GABA-A Receptor Antagonists; Hypothalamo-Hypophyseal System; Isoquinolines; Picrotoxin; Pituitary-Adrenal System; Rats; Receptors, GABA-A | 1993 |
Effects of GABA antagonists on inhibitory avoidance.
Topics: Animals; Avoidance Learning; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Picrotoxin; Rats; Rats, Wistar | 1993 |
GABA responses and their partial occlusion by glycine in cultured rat medullary neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Electrophysiology; Evoked Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons; Picrotoxin; Pregnancy; Rats; Strychnine | 1993 |
Morphological and functional consequences of chronic epilepsy in rat hippocampal slice cultures.
Topics: Animals; Bicuculline; Chronic Disease; Culture Techniques; Disease Models, Animal; Electrophysiology; Epilepsy; Hippocampus; Neurons; Picrotoxin; Rats | 1993 |
Pharmacologically induced elements of the hunting and feeding behavior in the pteropod mollusk Clione limacina. I. Effects of GABA.
Topics: Animals; Baclofen; Bicuculline; Brain; Electrophysiology; Extremities; Feeding Behavior; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Ganglia; Immunoenzyme Techniques; Locomotion; Mollusca; Nerve Net; Neurons; Neurons, Efferent; Picrotoxin; Predatory Behavior; Tissue Embedding | 1993 |
GABAergic control of odor-induced activity in the frog olfactory bulb: electrophysiological study with picrotoxin and bicuculline.
Topics: Action Potentials; Animals; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Odorants; Olfactory Bulb; Picrotoxin; Rana ridibunda; Stimulation, Chemical | 1993 |
Neuroactive steroids modulate GABA inhibition of hypothalamic somatostatin release.
Topics: Animals; Bicuculline; Cells, Cultured; Desoxycorticosterone; Drug Synergism; GABA Antagonists; GABA Modulators; Hypothalamus; Neurons; Picrotoxin; Pregnanolone; Rats; Rats, Sprague-Dawley; Somatostatin | 1995 |
GABA transport and calcium dynamics in horizontal cells from the skate retina.
Topics: Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Dantrolene; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscle Relaxants, Central; Nifedipine; Picrotoxin; Retina; Skates, Fish | 1995 |
Electrophysiological characterization of GABAA receptors in anterior pituitary cells of newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Diazepam; Drug Tolerance; Electric Conductivity; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pituitary Gland, Anterior; Rats; Receptors, GABA; Zinc | 1995 |
L-lysine is a barbiturate-like anticonvulsant and modulator of the benzodiazepine receptor.
Topics: Animals; Anions; Anticonvulsants; Barbiturates; Bicuculline; Brain Chemistry; Cattle; Central Nervous System Depressants; Diazepam; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentobarbital; Picrotoxin; Radioligand Assay; Receptors, GABA-A; Stimulation, Chemical | 1995 |
Regulation of anxiety by GABAA receptors in the rat amygdala.
Topics: Amygdala; Animals; Anxiety; Bicuculline; Interpersonal Relations; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
[The effect of salicylates on the toxicity of GABAlytics for mice].
Topics: Animals; Aspirin; Bicuculline; Drug Interactions; GABA Antagonists; Male; Mice; Picrotoxin; Protein Synthesis Inhibitors; Receptors, GABA-A; Salicylates; Salicylic Acid; Serum Albumin | 1995 |
GABA receptors in the dorsal motor nucleus of the vagus influence feline lower esophageal sphincter and gastric function.
Topics: Animals; Bicuculline; Cats; Esophagogastric Junction; Female; Ganglia, Spinal; Gastrointestinal Motility; Male; Microinjections; Motor Neurons; Muscimol; Picrotoxin; Receptors, GABA; Vagus Nerve | 1995 |
Characterization of GABA current in rat septal cholinergic neurons in culture and its modulation by metal cations.
Topics: Acetylcholine; Animals; Anions; Bicuculline; Cations; Cells, Cultured; GABA-A Receptor Antagonists; Metals; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, GABA-A; Septum Pellucidum | 1995 |
Rise in intracellular calcium via a nongenomic effect of allopregnanolone in fetal rat hypothalamic neurons.
Topics: Animals; Bicuculline; Calcium; Cell Membrane; Electrophysiology; Fetus; GABA Modulators; Hypothalamus; Neurons; Pertussis Toxin; Picrotoxin; Pregnanolone; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Virulence Factors, Bordetella | 1996 |
High level of footshock during inhibitory avoidance training prevents amnesia induced by intranigral injection of GABA antagonists.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Male; Picrotoxin; Rats; Rats, Wistar; Substantia Nigra | 1996 |
Effects of GABA receptor antagonists on the raphe magnus-induced inhibition of bulbar and spinal respiratory neural activities in the cat.
Topics: Animals; Baclofen; Bicuculline; Cats; Female; GABA Antagonists; Male; Medulla Oblongata; Neurons; Picrotoxin; Receptors, GABA; Respiration; Spinal Cord | 1995 |
Morphological plasticity in dendritic spines of cultured hippocampal neurons.
Topics: Action Potentials; Animals; Bicuculline; Cells, Cultured; Dendrites; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Microscopy, Confocal; Neuronal Plasticity; Neurons; Picrotoxin; Rats; Rats, Wistar; Tetrodotoxin | 1996 |
Glycine and GABAA receptor-mediated chloride fluxes in synaptoneurosomes from different parts of the rat brain.
Topics: Animals; Bicuculline; Brain; Chloride Channels; Glycine; Male; Membrane Potentials; Picrotoxin; Potassium Chloride; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Strychnine; Synaptosomes | 1996 |
GABAergic inhibitory response of locus coeruleus neurons to caloric vestibular stimulation in rats.
Topics: Action Potentials; Animals; Bicuculline; Ear, Inner; Electric Stimulation; Energy Intake; Female; GABA-A Receptor Antagonists; Locus Coeruleus; Male; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Vestibule, Labyrinth | 1996 |
The agonistic action of pentobarbital on GABAA beta-subunit homomeric receptors.
Topics: Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Mice; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Xenopus | 1996 |
A novel synaptic interaction underlying induction of long-term depression in the area CA1 of adult rat hippocampus.
Topics: Action Potentials; Animals; Bicuculline; Electric Stimulation; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1996 |
Effects of GABAergic drugs on physostigmine-induced yawning in rats.
Topics: Animals; Baclofen; Bicuculline; Cholinesterase Inhibitors; Drug Interactions; GABA Agonists; GABA Antagonists; Male; Muscimol; Physostigmine; Picrotoxin; Rats; Rats, Wistar; Yawning | 1995 |
Role of amino acids in salivation and the localization of their receptors in the rat salivary gland.
Topics: Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, GABA; Salivary Glands; Salivation; Sublingual Gland; Submandibular Gland; Superior Cervical Ganglion | 1995 |
Zinc enhances ionic currents induced in skate Müller (glial) cells by the inhibitory neurotransmitter GABA.
Topics: Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Transport; Neuroglia; Picrotoxin; Receptors, GABA-A; Retina; Signal Transduction; Skates, Fish; Zinc | 1996 |
Pentobarbital modulatory effect on GABA binding sites in developing chick optic lobe.
Topics: Animals; Bicuculline; Brain; Chick Embryo; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Pentobarbital; Picrotoxin; Sesterterpenes; Synaptic Membranes | 1995 |
Piracetam and aniracetam antagonism of centrally active drug-induced antinociception.
Topics: Analgesics; Analgesics, Opioid; Animals; Baclofen; Bicuculline; Male; Mice; Morphine; Nootropic Agents; Pain Measurement; Pain Threshold; Picrotoxin; Piracetam; Postural Balance; Pyrrolidinones; Receptors, GABA-B | 1996 |
GABAergic inhibitory inputs to subfornical organ neurons in rat slice preparations.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Subfornical Organ | 1995 |
GABA-induced responses in electrophysiologically characterized neurons within the rat rostro-ventrolateral medulla in vitro.
Topics: Animals; Baclofen; Bicuculline; Brain Stem; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Conduction System; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Synapses | 1996 |
Distinct effects of N omega-nitro-L-arginine on seizures induced by several drugs in mice.
Topics: Animals; Arginine; Bicuculline; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Picrotoxin; Seizures; Time Factors | 1996 |
Suppression by GABAB receptors of 4-aminopyridine-induced hyperactivity in guinea-pig dentate neurons.
Topics: 4-Aminopyridine; Animals; Bicuculline; Dentate Gyrus; Guinea Pigs; Hippocampus; Membrane Potentials; Picrotoxin; Receptors, GABA-B | 1996 |
N-methyl-D-aspartate receptors mediate a slow excitatory postsynaptic potential in the rat midbrain dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Dopamine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketamine; Membrane Potentials; Mesencephalon; Neurons; Picrotoxin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission; Tegmentum Mesencephali; Tetrodotoxin; Time Factors | 1996 |
Receptive field of the retinal bipolar cell: a pharmacological study in the tiger salamander.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Animals; Bicuculline; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; In Vitro Techniques; Photoreceptor Cells; Picrotoxin; Receptors, Glycine; Retina; Retinal Cone Photoreceptor Cells; Strychnine; Visual Pathways | 1996 |
Quantal properties of spontaneous EPSCs in neurones of the guinea-pig dorsal lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Guinea Pigs; In Vitro Techniques; Kinetics; Neurons; Patch-Clamp Techniques; Picrotoxin; Quantum Theory; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1996 |
Propofol inhibits epileptiform activity in rat hippocampal slices.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Anticonvulsants; Bicuculline; Convulsants; Drug Evaluation, Preclinical; Epilepsy; GABA Antagonists; Hypnotics and Sedatives; In Vitro Techniques; Male; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley | 1996 |
Susceptibility to drug-induced seizures of Fyn tyrosine kinase-deficient mice.
Topics: Animals; Bicuculline; Mice; Mice, Inbred Strains; Pentylenetetrazole; Picrotoxin; Protein-Tyrosine Kinases; Seizures | 1996 |
GABAergic influences on plus-maze behaviour in mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Diazepam; GABA Modulators; Male; Mice; Mice, Inbred DBA; Muscimol; Nipecotic Acids; Oximes; Picrotoxin; Valproic Acid | 1996 |
A functional comparison of the antagonists bicuculline and picrotoxin at recombinant GABAA receptors.
Topics: Animals; Bicuculline; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Humans; Membrane Potentials; Mice; Oocytes; Patch-Clamp Techniques; Picrotoxin; Recombinant Proteins; Xenopus laevis | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
GABAA receptor stimulation promotes survival of embryonic rat striatal neurons in culture.
Topics: Animals; Baclofen; Bicuculline; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Corpus Striatum; Embryo, Mammalian; GABA Antagonists; Neurons; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Stimulation, Chemical | 1997 |
Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit.
Topics: Animals; Anticonvulsants; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Chloride Channels; Convulsants; Diazepam; DNA, Complementary; Female; gamma-Aminobutyric Acid; Humans; Kinetics; Macromolecular Substances; Male; Membrane Potentials; Oocytes; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Triazoles; Xenopus laevis | 1996 |
[Effect of muscimol on the delay in desensitization of GABA-receptor/Cl--ionophor complex induced by picrotoxin and bicuculline].
Topics: Animals; Bicuculline; Chloride Channels; GABA Agonists; GABA Antagonists; In Vitro Techniques; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA; Synaptosomes | 1996 |
Two types of identified ascending interneurons with distinct GABA receptors in the crayfish terminal abdominal ganglion.
Topics: Animals; Astacoidea; Bicuculline; Chlorides; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; In Vitro Techniques; Interneurons; Male; Muscimol; Muscles; Picrotoxin; Receptors, GABA | 1997 |
Cholinergic and GABAergic modulation of self-stimulation of lateral hypothalamus and ventral tegmentum: effects of carbachol, atropine, bicuculline, and picrotoxin.
Topics: Animals; Atropine; Bicuculline; Carbachol; Electric Stimulation; GABA Antagonists; Hypothalamic Area, Lateral; Male; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Self Stimulation; Ventral Tegmental Area | 1997 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Involvement of GABAB receptors in the antinociception induced by baclofen in the formalin test.
Topics: Animals; Baclofen; Bicuculline; Formaldehyde; GABA Agonists; GABA Antagonists; Male; Pain Threshold; Picrotoxin; Rats; Receptors, GABA-B | 1997 |
Pharmacological evidence for two types of postsynaptic glycinergic receptors on the Mauthner cell of 52-h-old zebrafish larvae.
Topics: Animals; Bicuculline; Chloride Channels; Fishes; Glycine; Larva; Medulla Oblongata; Membrane Potentials; Metamorphosis, Biological; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Receptors, Glycine; Synaptic Transmission; Tetrodotoxin | 1997 |
Long-term potentiation induced by single volley activation: a mechanism for bicuculline-induced enhancement of synaptic field potentials in the CA1 hippocampal region.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Calcium; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Magnesium; Male; Picrotoxin; Pyramidal Cells; Receptors, GABA-A; Synaptic Transmission; Time Factors | 1997 |
GABA(A) receptor activation triggers a Cl- conductance increase and a K+ channel blockade in cerebellar granule cells.
Topics: Animals; Barium; Bicuculline; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Receptors, GABA-A; Time Factors | 1997 |
GABA(A) receptor blockade in the anterior ventral tegmental area increases extracellular levels of dopamine in the nucleus accumbens of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Homovanillic Acid; Microdialysis; Microinjections; Muscimol; Nucleus Accumbens; Picrotoxin; Rats; Rats, Wistar; Self Administration; Ventral Tegmental Area | 1997 |
The synaptic activation of kainate receptors.
Topics: 2-Amino-5-phosphonovalerate; Aminoquinolines; Animals; Benzodiazepines; Bicuculline; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Synapses | 1997 |
Sex differences in the response to GABA antagonists depend on the route of drug administration.
Topics: Animals; Bicuculline; Convulsants; Female; GABA Antagonists; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred C3H; Picrotoxin; Rats; Rats, Wistar; Sex Characteristics; Species Specificity | 1997 |
Bicuculline methiodide potentiates NMDA-dependent burst firing in rat dopamine neurons by blocking apamin-sensitive Ca2+-activated K+ currents.
Topics: Action Potentials; Animals; Apamin; Bicuculline; Calcium; Dopamine; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Ion Channel Gating; Male; N-Methylaspartate; Neurons; Periodicity; Picrotoxin; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tetrodotoxin; Ventral Tegmental Area | 1997 |
Inhibitory effects of corymine, an alkaloidal component from the leaves of Hunteria zeylanica, on glycine receptors expressed in Xenopus oocytes.
Topics: Alkaloids; Animals; Bicuculline; Brain; Convulsants; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Midazolam; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Plant Leaves; Rats; Receptors, GABA-A; Receptors, Glycine; Trees; Xenopus | 1997 |
Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Bicuculline; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pain; Picrotoxin; Receptors, GABA; Tail | 1997 |
Functional properties of perigeniculate inhibition of dorsal lateral geniculate nucleus thalamocortical neurons in vitro.
Topics: Acetazolamide; Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Convulsants; Electrophysiology; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Male; Membrane Potentials; Neural Inhibition; Neural Pathways; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Thalamic Nuclei | 1997 |
Inhibitory interactions between perigeniculate GABAergic neurons.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Axons; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Excitatory Postsynaptic Potentials; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Male; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Tetrodotoxin; Thalamic Nuclei | 1997 |
Selective antagonism of the GABA(A) receptor by ciprofloxacin and biphenylacetic acid.
Topics: Adenosine Triphosphate; Animals; Bicuculline; Ciprofloxacin; Dimethylphenylpiperazinium Iodide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglionic Stimulants; In Vitro Techniques; Male; Optic Nerve; Phenylacetates; Picrotoxin; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Vagus Nerve | 1997 |
Properties of calcium spikes revealed during GABAA receptor antagonism in hippocampal CA1 neurons from guinea pigs.
Topics: Animals; Bicuculline; Cadmium; Calcium; Calcium Channel Blockers; Electric Stimulation; Electrophysiology; Evoked Potentials; GABA-A Receptor Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Lidocaine; Nifedipine; omega-Agatoxin IVA; Picrotoxin; Pyramidal Cells; Sodium Channel Blockers; Spider Venoms; Tetrodotoxin; Virulence Factors, Bordetella | 1997 |
Pharmacology of skeletal muscle GABA-gated chloride channels in the cockroach Periplaneta americana.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Isonicotinic Acids; Male; Motor Neurons; Muscle, Skeletal; Periplaneta; Picrotoxin; Receptors, GABA; Sesterterpenes | 1997 |
Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Arousal; Bicuculline; Blood Pressure; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Picrotoxin; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Inhibitory effect of sex steroids on guinea-pig airway smooth muscle contractions.
Topics: Animals; Bicuculline; Calcium; GABA Antagonists; GABA-A Receptor Antagonists; Guinea Pigs; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Picrotoxin; Pregnanolone; Progesterone; Trachea | 1997 |
Astrocytes regulate amino acid receptor current densities in embryonic rat hippocampal neurons.
Topics: Animals; Astrocytes; Bicuculline; Calcium; Cells, Cultured; Chloride Channels; Fluorescent Antibody Technique; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; Microscopy, Phase-Contrast; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, Amino Acid; Receptors, GABA-A; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1997 |
Currents evoked by GABA and glycine in acutely dissociated neurons from the rat medial preoptic nucleus.
Topics: Animals; Bicuculline; Cells, Cultured; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Ion Channel Gating; Ligands; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Strychnine | 1997 |
Synaptic inputs to stellate cells in the ventral cochlear nucleus.
Topics: Action Potentials; Animals; Auditory Perception; Bicuculline; Cochlear Nucleus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Interneurons; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Models, Neurological; Nerve Fibers; Neurons; Picrotoxin; Quinoxalines; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Strychnine; Synapses; Vestibulocochlear Nerve | 1998 |
Abnormal synaptic transmission in the olfactory bulb of Fyn-kinase-deficient mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Crosses, Genetic; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Heterozygote; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Neurons; Neuroprotective Agents; Olfactory Bulb; Picrotoxin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Receptors, Glutamate; Synaptic Transmission | 1998 |
Enhancement of synaptic excitation by GABAA receptor antagonists in rat embryonic midbrain culture.
Topics: Action Potentials; Animals; Bicuculline; Cadmium; Convulsants; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Membrane Potentials; Mesencephalon; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin | 1998 |
Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1998 |
Desensitization of the GABAA receptor shifts the dynamic range of retinal horizontal cells due to light and dark adaptation.
Topics: Adaptation, Ocular; Animals; Bicuculline; Carps; Chloride Channels; Computer Simulation; Dopamine; Electrophysiology; GABA Antagonists; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Models, Neurological; Neurons; Picrotoxin; Receptors, GABA-A; Retina; Retinal Cone Photoreceptor Cells | 1997 |
Different GABA-receptor types are involved in the 5-HT-induced antinociception at the spinal level: a behavioral study.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Serotonin; Spinal Cord | 1998 |
Inhibitory neuronal activity can compensate for adverse effects of beta-amyloid in hippocampal neurons.
Topics: Amyloid beta-Peptides; Animals; Bicuculline; Calcium; Cell Survival; GABA Antagonists; Hippocampus; Homeostasis; Neural Inhibition; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1998 |
Age-dependent and cell class-specific modulation of retinal ganglion cell bursting activity by GABA.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Electrophysiology; Female; Ferrets; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Membrane Potentials; Periodicity; Picrotoxin; Pregnancy; Pyridazines; Retinal Ganglion Cells; Strychnine | 1998 |
GABA modulates color-opponent bipolar cells in carp retina.
Topics: Action Potentials; Animals; Bicuculline; Color Perception; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; Picrotoxin; Receptors, GABA-A; Retina | 1998 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
Effect of bicuculline on thalamic activity: a direct blockade of IAHP in reticularis neurons.
Topics: Animals; Apamin; Bicuculline; Calcium; Electric Stimulation; Electrophysiology; GABA Antagonists; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channels; Rats; Rats, Wistar; Thalamus | 1998 |
Carrier-mediated GABA release activates GABA receptors on hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Carrier Proteins; Cells, Cultured; Fetus; GABA Agents; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Neurons; Nipecotic Acids; Organic Anion Transporters; Oximes; Patch-Clamp Techniques; Picrotoxin; Potassium; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium; Tetrodotoxin | 1998 |
Spatiotemporal patterns at the retinal output.
Topics: Ambystoma; Animals; Bicuculline; GABA-A Receptor Antagonists; In Vitro Techniques; Models, Neurological; Neurons; Pattern Recognition, Visual; Picrotoxin; Reaction Time; Receptors, Glycine; Retina; Retinal Cone Photoreceptor Cells; Retinal Ganglion Cells; Strychnine | 1998 |
GABA-evoked depolarisations in the rat cortical wedge: involvement of GABAA receptors and HCO3- ions.
Topics: Animals; Bicarbonates; Bicuculline; Cerebral Cortex; Chlordiazepoxide; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Ions; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
EAA receptors in the dorsomedial hypothalamic area mediate the cardiovascular response to activation of the amygdala.
Topics: Amygdala; Animals; Bicuculline; Brain Mapping; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Heart Rate; Kynurenic Acid; Male; Microinjections; Picrotoxin; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Time Factors | 1998 |
Embryonic rat hippocampal neurons and GABAA receptor subunit-transfected non-neuronal cells release GABA tonically.
Topics: Animals; Bicuculline; Cell Line; Cells, Cultured; Chloride Channels; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, GABA-A; Sodium Chloride; Transfection | 1998 |
[Mechanisms of development of elevated seizure readiness during norbornene intoxication].
Topics: Animals; Bicuculline; Chloride Channels; Convulsants; Dopamine Antagonists; GABA Agonists; GABA Antagonists; Kindling, Neurologic; Lethal Dose 50; Male; Mice; Muscarinic Agonists; Norbornanes; Picrotoxin; Receptors, GABA-A; Seizures | 1998 |
GABAergic drugs and sexual behaviour in the rabbit: evidence for species-specific effects.
Topics: Animals; Baclofen; Bicuculline; Copulation; Dose-Response Relationship, Drug; Escape Reaction; GABA Agents; Isoxazoles; Male; Picrotoxin; Rabbits; Rats; Sexual Behavior, Animal; Species Specificity; Structure-Activity Relationship | 1998 |
Functional characterization and visualization of a GABAA receptor-GFP chimera expressed in Xenopus oocytes.
Topics: Anesthetics; Animals; Bicuculline; Cell Membrane; Desoxycorticosterone; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Ion Channel Gating; Luminescent Proteins; Membrane Potentials; Microscopy, Confocal; Midazolam; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Fusion Proteins; Xenopus laevis | 1998 |
Initially expressed early rat embryonic GABA(A) receptor Cl- ion channels exhibit heterogeneous channel properties.
Topics: Animals; Benzodiazepines; Bicuculline; Chloride Channels; Electric Conductivity; Embryonic and Fetal Development; GABA Antagonists; Gestational Age; Immunohistochemistry; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord | 1998 |
Inhibitory action of CGS 21680 on cerebral cortical neurons is antagonized by bicuculline and picrotoxin-is GABA involved?
Topics: Action Potentials; Adenosine; Animals; Bicuculline; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neurons; Phenethylamines; Picrotoxin; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley | 1998 |
GABA excites immature CA3 pyramidal cells through bicuculline-sensitive and -insensitive chloride-dependent receptors.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Chloride Channels; Culture Techniques; Evoked Potentials; gamma-Aminobutyric Acid; Kynurenic Acid; Nipecotic Acids; Patch-Clamp Techniques; Picrotoxin; Proline; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, GABA-B; Zinc | 1998 |
Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes.
Topics: Aminobutyrates; Anesthesia, General; Anesthetics, Intravenous; Animals; Baclofen; Bicuculline; Calcium; Cerebral Cortex; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Nerve Endings; Nipecotic Acids; Picrotoxin; Potassium Chloride; Proline; Propofol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Synaptic Transmission; Synaptosomes; Tritium | 1998 |
Differential effects of GABAA receptor antagonists in the control of respiratory neuronal discharge patterns.
Topics: Animals; Bicuculline; Dogs; Drug Antagonism; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Motor Neurons; Periodicity; Picrotoxin; Receptors, GABA-A; Respiratory Mechanics; Spinal Cord; Stereotaxic Techniques | 1998 |
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Strychnine; Time Factors; Weaning | 1999 |
Effects of GABA on acutely isolated neurons from the gustatory zone of the rat nucleus of the solitary tract.
Topics: Animals; Baclofen; Bicuculline; Cell Membrane; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Solitary Nucleus | 1998 |
Effects of pregnanolone on behavioural parameters and the responses to GABA(A) receptor antagonists in the late gestation fetal sheep.
Topics: Animals; Bicuculline; Electroencephalography; Electromyography; Electrooculography; Embryonic and Fetal Development; Female; GABA Antagonists; Gestational Age; Picrotoxin; Pregnancy; Pregnanolone; Receptors, GABA-A; Respiration; Sheep | 1999 |
A reexamination of the role of GABA in the mammalian suprachiasmatic nucleus.
Topics: Action Potentials; Animals; Bicuculline; Cell Membrane Permeability; Chlorides; Circadian Rhythm; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gramicidin; In Vitro Techniques; Male; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Suprachiasmatic Nucleus | 1999 |
Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo.
Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Nerve Degeneration; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Substantia Nigra | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
GABA(A) receptors mediate inhibition of T cell responses.
Topics: Amidines; Animals; Autocrine Communication; Bicuculline; CD3 Complex; Cell Division; Enzyme Inhibitors; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hypersensitivity, Delayed; Immunosuppression Therapy; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred NOD; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; T-Lymphocytes; Vigabatrin | 1999 |
Gamma-aminobutyric acid (GABA) A and B receptors mediate the stimulatory effects of GABA on the human sperm acrosome reaction: interaction with progesterone.
Topics: Acrosome; Analysis of Variance; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Picrotoxin; Progesterone; Prospective Studies; Receptors, GABA-A; Receptors, GABA-B | 1999 |
GABA(A) and GABA(B) antagonists differentially affect the firing pattern of substantia nigra dopaminergic neurons in vivo.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Dopamine; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Kinetics; Male; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra | 1999 |
Sodium action potentials are not required for light-evoked release of GABA or glycine from retinal amacrine cells.
Topics: Action Potentials; Ambystoma; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; In Vitro Techniques; Photic Stimulation; Picrotoxin; Retina; Sodium Channel Blockers; Sodium Channels; Strychnine; Tetrodotoxin | 1999 |
Bicuculline-resistant, Cl- dependent GABA response in the rat spinal dorsal horn.
Topics: Animals; Bicuculline; Chloride Channels; Evoked Potentials; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Gelatinosa; Thiopental | 1999 |
GABA(A) receptors modulate ethanol-induced conditioned place preference and taste aversion in mice.
Topics: Animals; Bicuculline; Central Nervous System Depressants; Conditioning, Psychological; Ethanol; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; Mice, Inbred DBA; Picrotoxin; Taste | 1999 |
Role of GABAA and GABAC receptors in the biphasic GABA responses in neurons of the rat major pelvic ganglia.
Topics: Animals; Bicuculline; Drug Resistance; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Parasympathetic; Male; Membrane Potentials; Neurons; Pelvis; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A | 1999 |
Interleukin-1beta causes a biphasic response in neurons of rat major pelvic ganglia.
Topics: Animals; Bicuculline; GABA Antagonists; Ganglia, Autonomic; Hypogastric Plexus; Interleukin-1; Membrane Potentials; Neurons; Peptide Fragments; Picrotoxin; Rats; Rats, Wistar | 1999 |
Clonidine action in spontaneously hypertensive rats (SHR) depends on the GABAergic system function.
Topics: Animals; Antihypertensive Agents; Bicuculline; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Down-Regulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Medulla Oblongata; Picrotoxin; Pons; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine.
Topics: Allosteric Regulation; Animals; Bicuculline; Conserved Sequence; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Leucine; Mutagenesis, Site-Directed; Mutation; Picrotoxin; Protein Structure, Tertiary; Rats; Receptors, GABA-A | 1999 |
Effects of GABAergic system on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Morphine Dependence; Muscimol; Naloxone; Narcotic Antagonists; Organophosphorus Compounds; Picrotoxin; Substance Withdrawal Syndrome | 1999 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
Excitotoxic cell death dependent on inhibitory receptor activation.
Topics: Action Potentials; Animals; Bicuculline; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebellar Cortex; Chick Embryo; Chloride Channels; Chlorides; Excitatory Amino Acid Agonists; GABA Antagonists; Glycine; Ion Channel Gating; Ion Transport; Kainic Acid; Neuroprotective Agents; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glycine; Retina; Strychnine | 1999 |
Response kinetics and pharmacological properties of heteromeric receptors formed by coassembly of GABA rho- and gamma 2-subunits.
Topics: Animals; Bass; Bicuculline; Diazepam; Dose-Response Relationship, Drug; GABA Antagonists; GABA Modulators; Humans; Neurons; Oocytes; Perches; Picrotoxin; Receptors, GABA; Retina; Xenopus; Zinc | 1999 |
Spontaneous and locomotor-related GABAergic input onto primary afferents in the neonatal rat.
Topics: Action Potentials; Afferent Pathways; Animals; Animals, Newborn; Bicuculline; Brain Stem; Chlorides; Decerebrate State; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Motor Activity; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Spinal Nerve Roots | 2000 |
Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbolines; Convulsants; Electroencephalography; Epilepsy, Absence; Frontal Lobe; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoniazid; Kainic Acid; Limbic System; Male; Parietal Lobe; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Strychnine | 2000 |
GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Pregnanediones; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Design and synthesis of anticonvulsive agents as gamma-vinyl GABA-based potential dual acting prodrugs and their biological activities.
Topics: Animals; Anticonvulsants; Bicuculline; Drug Design; Mice; Pentylenetetrazole; Picrotoxin; Prodrugs; Seizures; Vigabatrin | 2000 |
Copper sensitivity in dorsal hippocampus slices.
Topics: Action Potentials; Animals; Bicuculline; Copper Sulfate; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Synapses | 2000 |
Electrophysiological properties of cholinergic and noncholinergic neurons in the ventral pallidal region of the nucleus basalis in rat brain slices.
Topics: Action Potentials; Animals; Barium; Basal Nucleus of Meynert; Bicuculline; Cesium; Choline O-Acetyltransferase; GABA Antagonists; Globus Pallidus; Immunohistochemistry; In Vitro Techniques; Ion Channels; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin | 2000 |
The taurine uptake inhibitor guanidinoethyl sulphonate is an agonist at gamma-aminobutyric acid(A) receptors in cultured murine cerebellar granule cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebellar Cortex; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Agonists; Intracellular Fluid; Membrane Potentials; Mice; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Taurine; Time Factors | 2000 |
Selective cytostatic and neurotoxic effects of avermectins and activation of the GABAalpha receptors.
Topics: Animals; Bicuculline; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Ivermectin; Male; Neuroblastoma; Neurons; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Septal Nuclei; Tumor Cells, Cultured | 1999 |
Functional role of NMDA autoreceptors in olfactory mitral cells.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoreceptors; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Neurons, Afferent; Nifedipine; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2000 |
Subcellular localization and complements of GABA(A) and GABA(C) receptors on bullfrog retinal bipolar cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cell Compartmentation; Cell Size; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Histamine; Imidazoles; Isoquinolines; Membrane Potentials; Picrotoxin; Presynaptic Terminals; Rana catesbeiana; Receptors, GABA; Receptors, GABA-A; Retina | 2000 |
GABA receptor antagonists modulate postmitotic cell migration in slice cultures of embryonic rat cortex.
Topics: Animals; Baclofen; Bicuculline; Bromodeoxyuridine; Cell Movement; Cellular Senescence; Cerebral Cortex; Chemotaxis; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Intermediate Filament Proteins; Mitosis; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Organ Culture Techniques; Picrotoxin; Pregnancy; Rats; Receptors, GABA-A | 2000 |
Pharmacology of GABA(A) receptors of retinal dopaminergic neurons.
Topics: Alkaline Phosphatase; Animals; Benzodiazepines; Bicuculline; Binding Sites; Dopamine; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Neurons; Osmolar Concentration; Patch-Clamp Techniques; Picrotoxin; Pregnanediones; Protein Isoforms; Receptors, GABA-A; Retina; Sesterterpenes; Triazoles; Zinc | 2000 |
Expression of GABA(C) receptor rho1 and rho2 subunits during development of the mouse retina.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Neurons, Afferent; Organophosphorus Compounds; Picrotoxin; Receptors, GABA; Retina; RNA, Messenger | 2000 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected].
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Bicuculline; Cells, Cultured; Female; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA-A; Steroids; Xenopus laevis | 2000 |
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol.
Topics: Animals; Bicuculline; Central Nervous System Depressants; Convulsants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Picrotoxin; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Reflex; Seizures; Sleep; Steroids | 2000 |
Additivity and independence of neuroprotective effects of GABAA and GABAB receptor agonists in complete global cerebral ischemia.
Topics: Animals; Baclofen; Bicuculline; Brain Ischemia; Drug Interactions; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Isoxazoles; Male; Mice; Mice, Inbred CBA; Muscimol; Neuroprotective Agents; Picrotoxin | 2000 |
Immunocytochemical and electrophysiological characterization of GABA receptors in the frog and turtle retina.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Electroretinography; GABA Agonists; GABA Antagonists; Imidazoles; Immunohistochemistry; Picrotoxin; Rana ridibunda; Receptors, GABA; Retina; Turtles | 2001 |
Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Mice; Midazolam; Models, Neurological; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Propofol; Pyridazines; Receptors, GABA-A | 2001 |
Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors.
Topics: Analysis of Variance; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Hyperalgesia; Hypnotics and Sedatives; Male; Pain Measurement; Pain Threshold; Phenobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord | 2001 |
The functional role of a bicuculline-sensitive Ca2+-activated K+ current in rat medial preoptic neurons.
Topics: Animals; Apamin; Bicuculline; Calcium; Charybdotoxin; Electric Stimulation; GABA Antagonists; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium; Preoptic Area; Rats; Rats, Sprague-Dawley | 2001 |
Seizure-like activity in the disinhibited CA1 minislice of adult guinea-pigs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Guinea Pigs; Hippocampus; Neural Inhibition; Neurons, Afferent; Organ Culture Techniques; Picrotoxin; Pyridazines; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2001 |
Odor responses and spontaneous oscillatory activity in tentacular nerves of the terrestrial slug, Limax marginatus.
Topics: Animals; Bicuculline; Electrophysiology; Ethanol; GABA Antagonists; Mollusca; Nervous System Physiological Phenomena; Odorants; Oscillometry; Picrotoxin; Smell | 2001 |
Functional pharmacology of GABA(A) receptors containing the chicken brain gamma 4 subunit.
Topics: Animals; Bicuculline; Brain Chemistry; Chickens; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis; Zinc | 2001 |
Kindling induces transient NMDA receptor-mediated facilitation of high-frequency input in the rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Dentate Gyrus; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Ion Channel Gating; Kindling, Neurologic; Nerve Tissue Proteins; Neural Pathways; Neuronal Plasticity; Patch-Clamp Techniques; Perforant Pathway; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
Postnatal development of inhibitory synaptic transmission in the rostral nucleus of the solitary tract.
Topics: Animals; Animals, Suckling; Bicuculline; Electric Stimulation; Evoked Potentials; GABA Antagonists; Membrane Potentials; Nerve Tissue Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Solitary Nucleus; Synaptic Transmission; Taste | 2001 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors.
Topics: Allosteric Regulation; Animals; Bicuculline; Electric Conductivity; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Xenopus laevis | 2001 |
Sevoflurane potentiates and blocks GABA-induced currents through recombinant alpha1beta2gamma2 GABAA receptors: implications for an enhanced GABAergic transmission.
Topics: Anesthetics, Inhalation; Bicuculline; Cell Line; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Kidney; Methyl Ethers; Picrotoxin; Receptors, GABA-A; Sevoflurane; Synaptic Transmission | 2001 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
Deterministic chaos and noise in three in vitro hippocampal models of epilepsy.
Topics: Animals; Bicuculline; Biomedical Engineering; Computer Simulation; Electrophysiology; Epilepsy; GABA Antagonists; Hippocampus; In Vitro Techniques; Magnesium; Male; Models, Neurological; Nonlinear Dynamics; Picrotoxin; Potassium; Rats; Rats, Sprague-Dawley; Stochastic Processes | 2001 |
Anticonvulsant activities of the FS-1 subfraction isolated from roots of Delphinium denudatum.
Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Epilepsy, Generalized; Magnoliopsida; Male; Mice; Muscle Contraction; Pentylenetetrazole; Picrotoxin; Plant Extracts; Plant Roots; Plants, Medicinal | 2001 |
Network and intrinsic contributions to carbachol-induced oscillations in the rat subiculum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Chelating Agents; Cholinergic Agonists; Egtazic Acid; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Male; Muscarinic Antagonists; Neural Pathways; Organophosphorus Compounds; Periodicity; Picrotoxin; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2001 |
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Injections, Intraventricular; Male; Mice; Pentobarbital; Picrotoxin; Pyrazines; Seizures; Sleep; Time Factors; Valproic Acid | 2001 |
Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Electroshock; Ethanol; Male; Mice; Pentylenetetrazole; Picrotoxin; Ranunculaceae; Solvents; Strychnine; Water | 2001 |
GABA(C) rho(1) subunits form functional receptors but not functional synapses in hippocampal neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Drug Resistance; Forecasting; gamma-Aminobutyric Acid; Hippocampus; Humans; Indicators and Reagents; Neural Inhibition; Neurons; Picrotoxin; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Ruthenium Red; Synapses; Synaptic Transmission | 2001 |
Morphological and electrophysiological evidence for an ionotropic GABA receptor of novel pharmacology.
Topics: Amacrine Cells; Animals; Bicuculline; Chick Embryo; Chickens; Excitatory Amino Acid Agonists; GABA Antagonists; In Vitro Techniques; Ion Transport; Kainic Acid; Lithium; Neurons; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA; Retina; Retinal Ganglion Cells | 2002 |
Cholinergic transmission via central synapses in the locust nervous system.
Topics: Acetylcholine; Animals; Atropine; Bicuculline; Bungarotoxins; Carbachol; Crotonates; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Grasshoppers; Interneurons; Muscimol; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Picrotoxin; Receptors, Nicotinic; Synapses; Synaptic Transmission; Tubocurarine | 2001 |
Activation of neuronal N-methyl-D-aspartate receptor channels by lipid emulsions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Cells, Cultured; Cerebral Cortex; Drug Carriers; Fat Emulsions, Intravenous; GABA Antagonists; Ion Channels; Membrane Potentials; Mice; Mice, Inbred BALB C; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Receptors, N-Methyl-D-Aspartate | 2002 |
Subunit composition and function of GABAA receptors of rat spermatozoa.
Topics: Animals; Base Sequence; Bicuculline; DNA Primers; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Protein Subunits; Rats; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermatozoa; Transcription, Genetic | 2002 |
Properties of the pathways from the lateral amygdal nucleus to basolateral nucleus and amygdalostriatal transition area.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Basal Ganglia; Bicuculline; Emotions; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Male; Neural Pathways; Organ Culture Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2002 |
Role of benzodiazepine-GABAA receptor complex in attenuation of U-50,488H-induced analgesia and inhibition of tolerance to its analgesia by ginseng total saponin in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Drug Tolerance; Drugs, Chinese Herbal; Flumazenil; Ginsenosides; Injections, Intraperitoneal; Male; Mice; Pain; Pain Threshold; Panax; Picrotoxin; Receptors, GABA-A; Receptors, Opioid, kappa; Saponins; Tail | 2002 |
Anticonvulsant activity of aqueous extract of Leonotis leonurus.
Topics: Animals; Anticonvulsants; Bicuculline; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Lamiaceae; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Seizures | 2002 |
Picrotoxin and bicuculline have different effects on lumbar spinal networks and motoneurons in the neonatal rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Interneurons; Motor Neurons; Nerve Net; Neural Inhibition; Neural Pathways; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Synaptic Transmission | 2002 |
Apnoeic response to stimulation of peripheral GABA receptors in rats.
Topics: Animals; Apnea; Bicuculline; Carotid Sinus; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Respiration; Respiratory Mechanics; Vagotomy | 2002 |
Prenatal diazepam exposure functionally alters the GABA(A) receptor that modulates [3H]noradrenaline release from rat hippocampal synaptosomes.
Topics: Allosteric Regulation; Animals; Baclofen; Bicuculline; Diazepam; Female; Fetal Proteins; GABA Agonists; GABA Antagonists; Hippocampus; Male; Mental Disorders; Nerve Tissue Proteins; Norepinephrine; Picrotoxin; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes | 2002 |
Peripheral GABAergic inhibition of spider mechanosensory afferents.
Topics: Afferent Pathways; Animals; Bicuculline; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Neurons, Afferent; Patch-Clamp Techniques; Picrotoxin; Sodium Channels; Spiders | 2002 |
Detection of molecules related to the GABAergic system in a single-cell eukaryote, Paramecium primaurelia.
Topics: 4-Aminobutyrate Transaminase; Acetylcholine; Aldehyde Oxidoreductases; Animals; Antibodies; Bicuculline; Boron Compounds; Choline O-Acetyltransferase; Fluorescent Dyes; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Paramecium; Picrotoxin; Receptors, GABA-A | 2002 |
An anticonvulsant profile of the ketogenic diet in the rat.
Topics: 3-Hydroxybutyric Acid; Animals; Anticonvulsants; Bicuculline; Convulsants; Dietary Fats; Disease Models, Animal; Electroencephalography; Male; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Strychnine; Survival Rate; Time Factors | 2002 |
Neurogenesis of gasping does not require inhibitory transmission using GABA(A) or glycine receptors.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glycine Agents; Hypoxia; In Vitro Techniques; Muscimol; Neural Inhibition; Perfusion; Phrenic Nerve; Picrotoxin; Rats; Receptors, GABA-A; Receptors, Glycine; Respiration; Statistics, Nonparametric; Strychnine | 2002 |
Relative picrotoxin insensitivity distinguishes ionotropic GABA receptor-mediated IPSCs in hippocampal interneurons.
Topics: Animals; Bicuculline; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Iontophoresis; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyramidal Cells; Pyridines; Receptors, GABA; Receptors, GABA-A; Zolpidem | 2002 |
CNS inhibitory effects of barakol, a constituent of Cassia siamia Lamk.
Topics: Animals; Anticonvulsants; Benzopyrans; Bicuculline; Cassia; Diazepam; Dopamine; Dose-Response Relationship, Drug; Male; Maze Learning; Methamphetamine; Pentylenetetrazole; Phenalenes; Phytotherapy; Picrotoxin; Plant Extracts; Rats; Rats, Wistar; Seizures; Sleep; Strychnine; Thiopental | 2002 |
The lemniscal-cuneate recurrent excitation is suppressed by strychnine and enhanced by GABAA antagonists in the anaesthetized cat.
Topics: Action Potentials; Animals; Bicuculline; Cats; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Male; Neural Inhibition; Neural Pathways; Neurons; Occipital Lobe; Picrotoxin; Skin; Strychnine | 2002 |
Fast synaptic transmission between striatal spiny projection neurons.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Memory, Short-Term; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Substantia Nigra; Synapses; Synaptic Transmission | 2002 |
Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.).
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sea Bream | 2002 |
GABA(C) receptors modulate the rod-driven ERG b-wave of the skate retina.
Topics: Animals; Bicuculline; Chloride Channels; Electroretinography; GABA Antagonists; In Vitro Techniques; Light; Picrotoxin; Receptors, GABA; Retina; Retinal Rod Photoreceptor Cells; Skates, Fish | 2002 |
[Locomotor behavior in rats after separate and simultaneous intrastriatal microinjections of GABA-ergic drugs].
Topics: Animals; Avoidance Learning; Behavior, Animal; Bicuculline; Conditioning, Classical; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Motor Activity; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 2002 |
Influence of several convulsants on the protective activity of a non-competitive AMPA/kainate antagonist, LY 300164, and lamotrigine against maximal electroshock in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; GABA Antagonists; Lamotrigine; Male; Mice; Picrotoxin; Protective Agents; Receptors, AMPA; Strychnine; Triazines | 2002 |
D2 antagonist-induced c-fos in an identified subpopulation of globus pallidus neurons by a direct intrapallidal action.
Topics: Animals; Benzazepines; Bicuculline; Dopamine Agents; Dopamine D2 Receptor Antagonists; GABA Agents; Globus Pallidus; Male; Muscimol; Neurons; Parvalbumins; Picrotoxin; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Sulpiride | 2003 |
GABA(A) receptor blockade antagonizes the immobilizing action of propofol but not ketamine or isoflurane in a dose-related manner.
Topics: Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bicuculline; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Glycine Agents; Infusions, Intravenous; Injections, Intraperitoneal; Isoflurane; Ketamine; Male; Picrotoxin; Propofol; Pulmonary Alveoli; Pyridazines; Rats; Rats, Sprague-Dawley; Strychnine | 2003 |
Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, is an antagonist at recombinant alpha1beta2gamma2L GABA(A) receptors.
Topics: Animals; Bicuculline; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Furans; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ginkgo biloba; Ginkgolides; Humans; Membrane Potentials; Oocytes; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Sesterterpenes; Xenopus laevis | 2003 |
Identification of active thoracic spinal segments responsible for tonic and bursting sympathetic discharge in neonatal rats.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Electrophysiology; GABA Antagonists; Glycine Agents; In Vitro Techniques; Magnesium; Oscillometry; Picrotoxin; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Splanchnic Nerves; Strychnine; Sympathetic Nervous System; Thoracic Vertebrae | 2003 |
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-Acetyltransferase; Disease Models, Animal; Efferent Pathways; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Locomotion; Muscarinic Antagonists; Muscimol; Muscle Tonus; N-Methylaspartate; Neural Inhibition; Picrotoxin; Stimulation, Chemical | 2003 |
Beta-alanine acts on glycine receptors in the rat sacral dorsal commissural neurons.
Topics: Animals; Animals, Newborn; beta-Alanine; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Glycine; Strychnine | 2003 |
Contribution of GABAergic inhibition to the responses of secondary vestibular neurons to head rotation in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Head; Iontophoresis; Neural Inhibition; Neurons; Picrotoxin; Rats; Reaction Time; Rotation; Vestibular Nerve; Vestibular Nuclei | 2003 |
Taurine activates strychnine-sensitive glycine receptors in neurons freshly isolated from nucleus accumbens of young rats.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Taurine | 2004 |
GABAA and glycine receptors in regulation of intercostal and abdominal expiratory activity in vitro in neonatal rat.
Topics: Abdominal Wall; Animals; Animals, Newborn; Bicuculline; Brain Stem; GABA Antagonists; GABA-A Receptor Antagonists; Glycine Agents; Hydrogen-Ion Concentration; In Vitro Techniques; Intercostal Muscles; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Respiratory Mechanics; Spinal Cord; Spinal Nerve Roots; Strychnine | 2003 |
GABAergic system in the anxiolytic effect of Proproten: experimental study.
Topics: Animals; Anti-Anxiety Agents; Antibodies; Behavior, Animal; Bicuculline; Diazepam; GABA-A Receptor Antagonists; Male; Picrotoxin; Rats; Receptors, GABA-A; S100 Proteins | 2003 |
Synaptic and membrane properties of neurons in the dorsomedial hypothalamus.
Topics: Amino Acids; Analysis of Variance; Anesthetics, Local; Animals; Bicuculline; Cell Membrane; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Hypothalamus; In Vitro Techniques; Male; Membrane Potentials; Neural Conduction; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Synapses; Tetrodotoxin; Valine | 2003 |
A modeling study suggests complementary roles for GABAA and NMDA receptors and the SK channel in regulating the firing pattern in midbrain dopamine neurons.
Topics: Animals; Apamin; Bicuculline; Computer Simulation; Dopamine; Drug Interactions; GABA Agonists; GABA Antagonists; In Vitro Techniques; Isonicotinic Acids; Male; Membrane Potentials; Mesencephalon; Models, Neurological; N-Methylaspartate; Neurons; Picrotoxin; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Small-Conductance Calcium-Activated Potassium Channels | 2004 |
Synaptic strength between motoneurons and terminals of the dorsolateral funiculus is regulated by GABA receptors in the turtle spinal cord.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Motor Neurons; Muscimol; Picrotoxin; Receptors, GABA; Spinal Cord; Synapses; Synaptic Transmission; Time Factors; Turtles | 2004 |
Initiation of spontaneous epileptiform events in the rat neocortex in vivo.
Topics: Animals; Bicuculline; Epilepsy; Evoked Potentials; GABA-B Receptor Antagonists; Male; Neocortex; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2004 |
EXP-1 is an excitatory GABA-gated cation channel.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; Antigens, Protozoan; Barium Compounds; Bicuculline; Caenorhabditis elegans; Cations; Chloride Channels; Chlorides; Cloning, Molecular; Dose-Response Relationship, Drug; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglionic Blockers; Gastrointestinal Tract; Green Fluorescent Proteins; Humans; Ion Channel Gating; Luminescent Proteins; Mecamylamine; Membrane Potentials; Molecular Sequence Data; Muscle Contraction; Muscles; Mutagenesis, Site-Directed; Neuromuscular Junction; Oocytes; Patch-Clamp Techniques; Phylogeny; Picrotoxin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sodium; Transfection; Xenopus laevis | 2003 |
Differential sensitivity of genetically Fast vs. Slow kindling rats strains to GABAergic convulsive agents.
Topics: Animals; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Kindling, Neurologic; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Long-Evans; Rats, Wistar; Species Specificity; Strychnine | 2003 |
Bicuculline-insensitive GABA-gated Cl- channels in the larval nervous system of the moth Manduca sexta.
Topics: Animals; Bicuculline; Chloride Channels; Chlorides; Drosophila; Drosophila Proteins; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Immunohistochemistry; In Vitro Techniques; Ion Channel Gating; Isoquinolines; Isotopes; Larva; Manduca; Nervous System; Neurons; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Time Factors | 2003 |
GABAA receptor subunit mRNA expression in cultured embryonic and adult human dorsal root ganglion neurons.
Topics: Aging; Bicuculline; Blotting, Southern; Cells, Cultured; Central Nervous System Stimulants; Drug Interactions; Embryo, Mammalian; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Critically timed ethanol exposure reduces GABAAR function on septal neurons developing in vivo but not in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Body Weight; Cells, Cultured; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Ethanol; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Penicillins; Picrotoxin; Pregnancy; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Septum of Brain; Streptomycin; Time Factors; Triazoles; Up-Regulation; Zinc; Zolpidem | 2004 |
Blockade of GABAA receptors disrupts isoperiodic neuronal oscillations in the intergeniculate leaflet of the rat.
Topics: Action Potentials; Animals; Bicuculline; Biological Clocks; Circadian Rhythm; Drug Administration Routes; GABA Antagonists; Geniculate Bodies; Immunohistochemistry; Male; Neurons; Neuropeptide Y; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA | 2004 |
Motor behavior in rats after separate and combined administration of GABAergic agents into the neostriatum.
Topics: Animals; Avoidance Learning; Bicuculline; Conditioning, Operant; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Motor Activity; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Reflex | 2004 |
Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Bicuculline; Calbindin 2; Calcium; Calcium-Binding Proteins; Cell Count; Cell Size; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Nerve Net; Parvalbumins; Picrotoxin; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Time Factors; Valine | 2004 |
Electrophysiological properties of mouse horizontal cell GABAA receptors.
Topics: Animals; Bicuculline; Carbolines; Diazepam; Electrophysiology; GABA Agonists; GABA Antagonists; GABA Modulators; In Vitro Techniques; Interneurons; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Picrotoxin; Pyridines; Receptors, GABA-A; Retina; Zolpidem | 2004 |
Principal neuron spiking: neither necessary nor sufficient for cerebral blood flow in rat cerebellum.
Topics: Action Potentials; Animals; Bicuculline; Cerebellum; Cerebrovascular Circulation; GABA Antagonists; Male; Picrotoxin; Purkinje Cells; Rats; Rats, Wistar; Synaptic Transmission | 2004 |
Reversal of hippocampal LTP by spontaneous seizure-like activity: role of group I mGluR and cell depolarization.
Topics: Animals; Bicuculline; Calcium; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; Models, Neurological; Neurons; Picrotoxin; Receptors, Metabotropic Glutamate; Seizures; Synaptic Transmission; Time Factors | 2005 |
Pregnenolone sulfate potentiates the effects of NMDA on hippocampal alanine and dopamine.
Topics: Alanine; Amino Acids; Animals; Bicuculline; Convulsants; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Male; Mice; Microinjections; N-Methylaspartate; Picrotoxin; Pregnenolone; Seizures | 2004 |
Coordinated excitatory effect of GABAergic interneurons on three feeding motor programs in the mollusk Clione limacina.
Topics: Animals; Behavior, Animal; Bicuculline; Excitatory Postsynaptic Potentials; Feeding Behavior; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Immunohistochemistry; Interneurons; Mollusca; Motor Neurons; Mouth; Nerve Net; Neural Inhibition; Periodicity; Picrotoxin | 2005 |
The anticonvulsant action of propofol on epileptiform activity in rat hippocampal slices.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aminophylline; Anesthetics, Intravenous; Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theobromine; Xanthines | 2004 |
Human follicular fluid stimulates the sperm acrosome reaction by interacting with the gamma-aminobutyric acid receptors.
Topics: Acrosome Reaction; Analysis of Variance; Baclofen; Bicuculline; Female; Follicular Fluid; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Humans; Male; Osmolar Concentration; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Sperm Motility; Spermatozoa | 2004 |
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
Topics: Animals; Bicuculline; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Ionophores; Membrane Potentials; Microscopy, Electron, Transmission; Models, Neurological; Neural Inhibition; Neurons; Nystatin; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Presynaptic Terminals; Pyridines; Quinoxalines; Retina; Time Factors; Valine | 2004 |
Changes in gamma-aminobutyric acid tone and extracellular serotonin in the dorsal raphe nucleus over the rat estrous cycle.
Topics: Animals; Bicuculline; Brain Chemistry; Estrogens; Estrous Cycle; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Microdialysis; Picrotoxin; Progesterone; Raphe Nuclei; Rats; Rats, Inbred WKY; Serotonin; Sex Factors | 2004 |
The supramammillary nucleus mediates primary reinforcement via GABA(A) receptors.
Topics: Animals; Baclofen; Benzazepines; Bicuculline; Discrimination, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Male; Mammillary Bodies; Microinjections; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Reinforcement, Psychology; Reward; Self Administration | 2005 |
Distinct roles of glycinergic and GABAergic inhibition in coordinating locomotor-like rhythms in the neonatal mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Motor Activity; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Picrotoxin; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine | 2005 |
Inner and outer retinal pathways both contribute to surround inhibition of salamander ganglion cells.
Topics: Animals; Bicuculline; Carbenoxolone; Cobalt; Excitatory Postsynaptic Potentials; GABA Antagonists; Neural Inhibition; Organ Culture Techniques; Photic Stimulation; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Retinal Ganglion Cells; Urodela | 2005 |
Rhythmic activity in a forebrain vocal control nucleus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Analysis of Variance; Animals; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Finches; GABA Antagonists; In Vitro Techniques; Male; Models, Neurological; Neurons; Patch-Clamp Techniques; Periodicity; Picrotoxin; Prosencephalon; Reaction Time; Synaptic Transmission; Vocalization, Animal | 2005 |
Taurine activates excitatory non-synaptic glycine receptors on dopamine neurones in ventral tegmental area of young rats.
Topics: Action Potentials; Age Factors; Animals; Bicuculline; Convulsants; Dopamine; gamma-Aminobutyric Acid; Glycine; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, Glycine; Strychnine; Taurine; Ventral Tegmental Area | 2005 |
Rapid and long-lasting tolerance to clomethiazole-induced hypothermia in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; Hypothermia; Injections, Subcutaneous; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Time Factors | 2005 |
Postsynaptic IP3 receptor-mediated Ca2+ release modulates synaptic transmission in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Age Factors; Animals; Animals, Newborn; Bicuculline; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium Channels; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation, Developmental; Hippocampus; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Receptors, Cytoplasmic and Nuclear; Synaptic Transmission; Thapsigargin; Time Factors | 2005 |
[The GABA-ergic regulation of the Lymnaea stagnalis (L.) dorsal longitudinal muscle contractions].
Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Lymnaea; Muscle Contraction; Muscles; Nerve Fibers; Picrotoxin | 2005 |
A noncanonical release of GABA and glutamate modulates neuronal migration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Bicuculline; Bromodeoxyuridine; Cell Movement; Dideoxynucleosides; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Immunohistochemistry; In Vitro Techniques; Mice; Mice, Mutant Strains; Mice, Transgenic; Microtubule-Associated Proteins; Munc18 Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2005 |
Spontaneous oscillatory activity of starburst amacrine cells in the mouse retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amacrine Cells; Aminobutyrates; Animals; Bicuculline; Biological Clocks; Cadmium Chloride; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Lysine; Membrane Potentials; Mice; Mice, Inbred ICR; Mice, Knockout; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Retina; Retinal Ganglion Cells; Shaw Potassium Channels; Tetraethylammonium; Time Factors | 2005 |
Subunit-dependent block by isoflurane of wild-type and mutant alpha(1)S270H GABA(A) receptor currents in Xenopus oocytes.
Topics: Anesthetics, Inhalation; Animals; Bicuculline; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Antagonists; Isoflurane; Membrane Potentials; Mutation; Oocytes; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Substrate Specificity; Xenopus | 2005 |
Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors.
Topics: Allosteric Regulation; Animals; Araliaceae; Bicuculline; Flumazenil; Flunitrazepam; GABA Modulators; Picrotoxin; Plant Extracts; Receptors, GABA-A; Xenopus laevis | 2005 |
Quinolinic acid toxicity on orexin neurons blocked by gamma aminobutyric acid type A receptor stimulation.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Magnesium; Neurons; Neuropeptides; Nipecotic Acids; Norepinephrine; Orexin Receptors; Orexins; Organophosphorus Compounds; Picrotoxin; Quinolinic Acid; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Selective Serotonin Reuptake Inhibitors; Serotonin | 2005 |
Dopamine D1 and D4 receptor subtypes differentially modulate recurrent excitatory synapses in prefrontal cortical pyramidal neurons.
Topics: Animals; Bicuculline; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Impedance; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Lysine; Male; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D4; Synapses | 2006 |
Nicotinic acetylcholine receptor subtypes involved in facilitation of GABAergic inhibition in mouse superficial superior colliculus.
Topics: Acetylcholine; Animals; Bicuculline; Bungarotoxins; Cadmium; Conotoxins; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Isoenzymes; Mecamylamine; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Neural Networks, Computer; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Pyridazines; Receptors, Nicotinic; Superior Colliculi | 2005 |
Divergent effects of bicuculline and picrotoxin on ketamine-induced apneustic breathing.
Topics: Animals; Apnea; Bicuculline; Blood Pressure; Cats; Disease Models, Animal; GABA Antagonists; GABA-A Receptor Antagonists; Inhalation; Injections, Intravenous; Ketamine; Phrenic Nerve; Picrotoxin; Receptors, GABA-A; Respiratory Mechanics | 2005 |
Repeated cocaine exposure in vivo facilitates LTP induction in midbrain dopamine neurons.
Topics: Animals; Bicuculline; Cocaine; Diazepam; Dopamine; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Male; Memory; Mesencephalon; Neuronal Plasticity; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 2005 |
Analgesic and anticonvulsant properties of Tetrapleura tetraptera (Taub) (Fabaceae) fruit aqueous extract in mice.
Topics: Acetic Acid; Analgesics; Animals; Anticonvulsants; Bicuculline; Female; Fruit; Hot Temperature; Male; Mice; Mice, Inbred BALB C; Pain; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Seizures; Tetrapleura | 2005 |
GABAergic signaling at mossy fiber synapses in neonatal rat hippocampus.
Topics: Action Potentials; Aminobutyrates; Animals; Animals, Newborn; Bicuculline; Cation Transport Proteins; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Agonists; Flurazepam; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Mossy Fibers, Hippocampal; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, GABA-A; Synaptic Transmission; Vesicular Glutamate Transport Protein 1 | 2006 |
The lack of bicuculline and picrotoxin influence on midazolam depressant action on brain oxygen consumption.
Topics: Animals; Bicuculline; Drug Interactions; Frontal Lobe; GABA Modulators; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Midazolam; Oxygen Consumption; Picrotoxin; Rats; Rats, Wistar | 2006 |
Molecular weight and subunit composition of the sensitive to GABA-ergic ligands Cl-/HCO3(-)-stimulated Mg2+-ATPase from plasma membrane of rat brain.
Topics: Animals; Bicarbonates; Bicuculline; Brain; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Chlorides; Chromatography, Gel; Electrophoresis, Gel, Two-Dimensional; gamma-Aminobutyric Acid; Molecular Weight; Picrotoxin; Protein Subunits; Rats; Receptors, GABA-A | 2005 |
Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Morphine; Muscimol; Narcotics; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time | 2006 |
Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Apoptosis; Bicuculline; Cell Survival; Cells, Cultured; Cerebellar Cortex; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Histamine; Histamine Agonists; Histamine Antagonists; N-Methylaspartate; Necrosis; Neurons; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Time Factors | 2006 |
Neuronal electrical high frequency stimulation enhances GABA outflow from human neocortical slices.
Topics: Bicuculline; Chromatography, High Pressure Liquid; Electric Stimulation; Electrochemistry; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Neocortex; Nerve Endings; Neurons; Picrotoxin; Sodium Channel Agonists; Veratridine | 2006 |
Effect of cyclooxygenase-2 (COX-2) inhibitors in various animal models (bicuculline, picrotoxin, maximal electroshock-induced convulsions) of epilepsy with possible mechanism of action.
Topics: Animals; Bicuculline; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Muscimol; Picrotoxin; Seizures | 2006 |
Supraspinal locomotor centers do/do not contribute significantly to the hyperpnea of dynamic exercise in humans.
Topics: Afferent Pathways; Animals; Autonomic Nervous System; Bicuculline; Carbon Dioxide; Central Nervous System Stimulants; Exercise; Humans; Hypocapnia; Hypothalamus; Locomotion; Physical Conditioning, Animal; Picrotoxin; Pulmonary Ventilation; Rats; Respiration; Respiratory Mechanics; Sheep | 2006 |
GABAA-Receptor blockade reverses the injury-induced sensitization of nociceptor-specific (NS) neurons in the spinal dorsal horn of the rat.
Topics: Action Potentials; Animals; Bicuculline; Capsaicin; Electrophysiology; Female; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mustard Plant; Neurons; Nociceptors; Pain; Physical Stimulation; Picrotoxin; Plant Oils; Posterior Horn Cells; Rats; Rats, Wistar; Stimulation, Chemical | 2006 |
Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Lethal Dose 50; Male; Mice; Mice, Inbred BALB C; Pentylenetetrazole; Persea; Phytotherapy; Picrotoxin; Plant Extracts; Plant Leaves; Seizures | 2006 |
Effect of GABA receptor agonists or antagonists on morphine-induced Straub tail in mice.
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; Hindlimb Suspension; Male; Mice; Morphine; Muscimol; Narcotics; Organophosphorus Compounds; Picrotoxin | 2006 |
A spontaneous tonic chloride conductance in solitary glutamatergic hippocampal neurons.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; GABA Antagonists; Glutamic Acid; Hippocampus; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Small-Conductance Calcium-Activated Potassium Channels; Synaptic Transmission | 2006 |
Role of GABAergic antagonism in the neuroprotective effects of bilobalide.
Topics: Animals; Area Under Curve; Bicuculline; Brain Edema; Bridged Bicyclo Compounds, Heterocyclic; Choline; Cyclopentanes; Drug Interactions; Excitatory Amino Acid Agonists; Furans; GABA Antagonists; gamma-Aminobutyric Acid; Ginkgolides; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuroprotective Agents; Nonlinear Dynamics; Picrotoxin; Rats; Rats, Sprague-Dawley; Synaptosomes | 2007 |
GABA excitation in mouse hilar neuropeptide Y neurons.
Topics: Animals; Bicuculline; Evoked Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Interneurons; Membrane Potentials; Mice; Mice, Transgenic; Neuropeptide Y; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Somatostatin | 2007 |
Contextual interaction of GABAergic circuitry with dynamic synapses.
Topics: Algorithms; Animals; Bicuculline; Brain Mapping; Chickens; Chloride Channels; Data Interpretation, Statistical; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Nerve Net; Photic Stimulation; Picrotoxin; Poisson Distribution; Retina; Superior Colliculi; Synapses; Visual Pathways | 2007 |
GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Bicuculline; Cyclopropanes; Enkephalin, Methionine; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Interneurons; Male; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Muscimol; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Pyridazines; Pyridinium Compounds; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin | 2007 |
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bumetanide; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycolates; Ion Channels; Mice; Mice, Inbred C57BL; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Nitrobenzoates; Patch-Clamp Techniques; Phloretin; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Quinine; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Somatosensory Cortex; Tetrodotoxin | 2007 |
Magnitude and ethanol sensitivity of tonic GABAA receptor-mediated inhibition in dentate gyrus changes from adolescence to adulthood.
Topics: Age Factors; Aging; Animals; Bicuculline; Central Nervous System Depressants; Central Nervous System Stimulants; Dentate Gyrus; Drug Interactions; Ethanol; GABA Antagonists; In Vitro Techniques; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2007 |
Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities.
Topics: Action Potentials; Animals; beta-Alanine; Bicuculline; Crotonates; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Furosemide; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Imidazoles; Microinjections; Mutation; Neural Inhibition; Neurons; Oocytes; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Sesterterpenes; Taurine; Xenopus laevis; Zinc | 2007 |
Anticonvulsant activity of Cotyledon orbiculata L. (Crassulaceae) leaf extract in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Crassulaceae; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Plant Leaves; Seizures | 2007 |
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy.
Topics: Acetamides; Animals; Anticonvulsants; Bicuculline; Cobalt; Convulsants; Electroshock; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Reflex; Excitatory Amino Acid Agonists; GABA Antagonists; Homocysteine; Kindling, Neurologic; Lacosamide; Male; Mice; N-Methylaspartate; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2007 |
Effects of postnatal caffeine exposure on seizure susceptibility in developing rats.
Topics: Age Factors; Aminophylline; Animals; Animals, Newborn; Behavior, Animal; Bicuculline; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Disease Susceptibility; Drug Interactions; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Seizures; Severity of Illness Index | 2007 |
Involvement of GABA A receptor-associated chloride channels in the peripheral antinociceptive effect induced by GABA A receptor agonist muscimol.
Topics: Analysis of Variance; Animals; Bicuculline; Chloride Channels; Dinoprostone; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Injections, Subcutaneous; Male; Muscimol; Pain; Pain Measurement; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Pressure; Rats; Rats, Wistar; Receptors, GABA-A | 2007 |
Dual GABAA receptor-mediated inhibition in rat presympathetic paraventricular nucleus neurons.
Topics: Animals; Bicuculline; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Medulla Oblongata; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Synapses | 2007 |
Anticonvulsant activity of Hypoxis hemerocallidea Fisch. & C. A. Mey. (Hypoxidaceae) corm ('African potato') aqueous extract in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Hypoxis; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Seizures | 2008 |
Characteristics of GABA receptors on the ocellar L-neurons of American cockroach Periplaneta americana.
Topics: Animals; Bicuculline; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Membrane Potentials; Muscimol; Neurons; Periplaneta; Picrotoxin; Receptors, GABA; Sodium Chloride | 2007 |
Effect of classic convulsants on Cl- conductance of the GABA(A) receptor complex in membranes of cerebral cortex cells at the early stage of kindling.
Topics: Animals; Bicuculline; Cerebral Cortex; Chloride Channels; Convulsants; Drug Synergism; GABA-A Receptor Agonists; Kindling, Neurologic; Male; Membranes; Muscimol; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes | 2007 |
Anticonvulsant property of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract.
Topics: Analysis of Variance; Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Mice; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Seizures | 2008 |
Disruption of GABAA in the insect antennal lobe generally increases odor detection and discrimination thresholds.
Topics: Animals; Bicuculline; Conditioning, Classical; Electromyography; Feeding Behavior; Female; GABA-A Receptor Antagonists; Male; Manduca; Odorants; Olfactory Bulb; Picrotoxin; Receptors, GABA-A; Sensory Thresholds; Smell | 2008 |
GABAa and GABAc receptor mediated influences on the intensity-response functions of the b- and d-wave in the frog ERG.
Topics: Adaptation, Ocular; Animals; Bicuculline; Dark Adaptation; Electroretinography; GABA Antagonists; GABA-A Receptor Antagonists; Photic Stimulation; Picrotoxin; Rana ridibunda; Receptors, GABA; Receptors, GABA-A; Retina | 2008 |
Control of sympathetic, respiratory and somatomotor outflow by an intraspinal pattern generator.
Topics: Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; Motor Activity; Motor Neurons; Picrotoxin; Rats; Respiration; Spinal Cord; Sympathetic Nervous System | 2008 |
Anticonvulsant effect of Rhus chirindensis (Baker F.) (Anacardiaceae) stem-bark aqueous extract in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Male; Mice; Mice, Inbred BALB C; Pentylenetetrazole; Picrotoxin; Plant Bark; Plant Extracts; Plant Stems; Rhus | 2008 |
Anticonvulsant characteristics of pyridoxyl-gamma-aminobutyrate, PL-GABA.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Drug Tolerance; Electrophysiology; Electroshock; Enzyme Inhibitors; Epilepsy; gamma-Aminobutyric Acid; Gerbillinae; Magnesium; Male; Mice; Mice, Inbred BALB C; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Seizures; Tissue Distribution | 2008 |
Developmental downregulation of GABAergic drive parallels formation of functional synapses in cultured mouse neocortical networks.
Topics: Animals; Bicuculline; Cells, Cultured; Dose-Response Relationship, Radiation; Down-Regulation; Electric Stimulation; Embryo, Mammalian; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; Interneurons; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Nerve Net; Nerve Tissue Proteins; Patch-Clamp Techniques; Picrotoxin; Synapses; Synaptic Transmission; Time Factors | 2008 |
Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer.
Topics: Bicuculline; Cell Proliferation; Colonic Neoplasms; Dihydroergotoxine; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Humans; Isonicotinic Acids; Male; Picrotoxin; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, GABA-A; Receptors, GABA-B; Tumor Cells, Cultured | 2008 |
Study of GABAA receptors on the sleep-like behavior in Coturnix japonica (Temminck Schlegel, 1849) (Galliformes: Aves).
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Coturnix; Dose-Response Relationship, Drug; GABA Agents; Male; Picrotoxin; Receptors, GABA-A; Sleep; Thiopental | 2009 |
Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential.
Topics: Anesthetics; Animals; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Proliferation; Cells, Cultured; Cytoplasm; Female; GABA Antagonists; Hippocampus; Neurons; Nifedipine; Picrotoxin; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Review Literature as Topic | 2008 |
Role of inhibitory neurotransmission in the control of canine hypoglossal motoneuron activity in vivo.
Topics: Action Potentials; Animals; Bicuculline; Biophysical Phenomena; Dogs; Female; GABA Antagonists; Glycine Agents; Hypoglossal Nerve; Male; Motor Neurons; Neural Inhibition; Phrenic Nerve; Picrotoxin; Serotonin; Strychnine | 2009 |
Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro.
Topics: Aconitine; Afferent Pathways; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bicuculline; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Pedunculopontine Tegmental Nucleus; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Nicotinic; Strontium; Synapses; Synaptic Transmission; Ventral Tegmental Area | 2009 |
Anticonvulsant activity of Nylandtia spinosa L. Dumont (Polygalaceae) aqueous and methanol leaf extracts in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Generalized; Lethal Dose 50; Male; Methanol; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Plant Extracts; Plant Leaves; Polygalaceae; Seizures; Solvents; Water | 2008 |
Synergistic roles of GABAA receptors and SK channels in regulating thalamocortical oscillations.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apamin; Bicuculline; Biological Clocks; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Neural Pathways; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Small-Conductance Calcium-Activated Potassium Channels; Thalamus | 2009 |
Spontaneous activity in the developing mouse midbrain driven by an external pacemaker.
Topics: Action Potentials; Age Factors; Animals; Bicuculline; Calcium; Choline O-Acetyltransferase; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Image Processing, Computer-Assisted; Immunohistochemistry; Mesencephalon; Mice; Nerve Net; Neurons; Picrotoxin; Rhombencephalon; Serotonin; Tyrosine 3-Monooxygenase | 2009 |
Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Synuclein; Animals; Animals, Newborn; Bicuculline; Biophysics; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Humans; In Vitro Techniques; Male; Mice; Mice, Transgenic; Neural Pathways; Neurons; Patch-Clamp Techniques; Picrotoxin; Sodium Channel Blockers; Synaptic Potentials; Tetrodotoxin | 2010 |
Disruption of ClC-2 expression is associated with progressive neurodegeneration in aging mice.
Topics: Aging; Animals; Astrocytes; Bicuculline; CA3 Region, Hippocampal; Cell Death; Chloride Channels; CLC-2 Chloride Channels; Electroencephalography; GABA Antagonists; Hippocampus; Immunoblotting; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Picrotoxin | 2010 |
GABAC receptors are functionally expressed in the intermediate zone and regulate radial migration in the embryonic mouse neocortex.
Topics: Animals; Bicuculline; Cell Movement; Crotonates; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neocortex; Neurons; Phosphinic Acids; Picrotoxin; Pyridines; Receptors, GABA; Receptors, GABA-A; RNA, Messenger | 2010 |
GABAa and GABAc receptor-mediated modulation of responses to color stimuli: electroretinographic study in the turtle Emys orbicularis.
Topics: Animals; Bicuculline; Color; Electroretinography; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Photic Stimulation; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Cone Photoreceptor Cells; Time Factors; Turtles; Vision, Ocular | 2010 |
Pre- and postsynaptic modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord.
Topics: Animals; Bicuculline; Furosemide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Motor Neurons; Picrotoxin; Presynaptic Terminals; Pyridazines; Receptors, GABA-A; Reflex, Monosynaptic; Spinal Cord; Synaptic Potentials; Turtles | 2010 |
Long-lasting intrinsic optical changes observed in the neurointermediate lobe of the mouse pituitary reflect volume changes in cells of the pars intermedia.
Topics: Action Potentials; Animals; Bicuculline; Calcium; Female; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Picrotoxin; Pituitary Gland, Intermediate; Receptors, GABA-A | 2010 |
Inactivation of GABA(A) receptor reduces ginsenoside Rb3 neuroprotection in mouse hippocampal slices after oxygen-glucose deprivation.
Topics: Animals; Bicuculline; China; Ethnopharmacology; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Ginsenosides; Glucose; Hippocalcin; Hypoxia; In Vitro Techniques; Male; Medicine, Chinese Traditional; Mice; Neuroprotective Agents; Panax; Picrotoxin; Plants, Medicinal; Synaptic Transmission | 2011 |
[The role of melatonin receptor and GABAA receptor in the sleeping time prolonged by melatonin in mice].
Topics: Animals; Bicuculline; Male; Melatonin; Mice; Mice, Inbred Strains; Picrotoxin; Prazosin; Receptors, GABA-A; Receptors, Melatonin; Sleep | 2003 |
Anaesthetic impairment of immune function is mediated via GABA(A) receptors.
Topics: Anesthetics; Bicuculline; Cell Line; Cysteine Loop Ligand-Gated Ion Channel Receptors; Drug Evaluation, Preclinical; GABA Antagonists; GABA-A Receptor Agonists; Humans; Immune System; Immune System Diseases; Immunocompromised Host; Monocytes; Muscimol; Picrotoxin; Receptors, GABA-A; Synaptic Transmission | 2011 |
Blockade of GABA(A) receptors in the paraventricular nucleus of the hypothalamus attenuates voluntary ethanol intake and activates the hypothalamic-pituitary-adrenocortical axis.
Topics: Alcohol Drinking; Alcoholism; Animals; Bicuculline; Corticosterone; GABA-A Receptor Antagonists; Hypothalamo-Hypophyseal System; Male; Paraventricular Hypothalamic Nucleus; Picrotoxin; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Receptors, GABA-A; Self Administration; Signal Transduction | 2011 |
[The influence of GABAA receptor on the analgesic action of intrathecally injected oxysophoridine].
Topics: Alkaloids; Analgesics; Animals; Bicuculline; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Muscimol; Pain Threshold; Picrotoxin; Random Allocation; Receptors, GABA-A; Spinal Cord | 2011 |
Bull sperm acrosome reaction induced by gamma-aminobutyric acid (GABA) is mediated by GABAergic receptors type A.
Topics: Acrosome Reaction; Animals; Bicuculline; Calcium Channel Blockers; Cattle; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin; Progesterone; Receptors, GABA-A; Spermatozoa | 2011 |
Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.
Topics: Actins; Aggression; Animals; Behavior, Animal; Bicuculline; Body Weight; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Embryo, Mammalian; Endophenotypes; Exploratory Behavior; Female; GABA Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Genotype; Glial Fibrillary Acidic Protein; Glycine; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Inhibition, Psychological; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Membrane Potentials; Memory, Short-Term; Mental Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Muscle Strength; Mutation; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Picrotoxin; Post-Synaptic Density; Psychomotor Performance; Receptors, AMPA; Receptors, Kainic Acid; Recognition, Psychology; Rotarod Performance Test; Sialoglycoproteins; Statistics, Nonparametric; Time Factors | 2011 |
Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization.
Topics: Bicuculline; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; HEK293 Cells; Humans; Ion Channel Gating; Mutation; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Receptors, Serotonin, 5-HT3 | 2012 |
Tonic GABAA receptor conductance in medial subnucleus of the tractus solitarius neurons is inhibited by activation of μ-opioid receptors.
Topics: Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Sodium Channel Blockers; Solitary Nucleus; Tetrodotoxin | 2012 |
Oxysophoridine through intrathecal injection induces antinociception and increases the expression of the GABAAα1 receptor in the spinal cord of mice.
Topics: Alkaloids; Analgesics; Animals; Bicuculline; Drug Evaluation, Preclinical; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Mice; Mice, Inbred ICR; Muscimol; Pain Measurement; Picrotoxin; Receptors, GABA-A; Spinal Cord | 2012 |
Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system.
Topics: Benzodiazepines; Bicuculline; Diazepam; GABA Agents; GABA Agonists; GABA Antagonists; GABA Modulators; Gene Expression; HEK293 Cells; High-Throughput Screening Assays; Humans; Imidazoles; Ion Channel Gating; Microfluidic Analytical Techniques; Muscimol; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection | 2012 |
The role of inhibition in oscillatory wave dynamics in the cortex.
Topics: Animals; Bicuculline; Carbachol; Epilepsies, Partial; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Membrane Potentials; Models, Neurological; Neocortex; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Theta Rhythm | 2012 |
Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation.
Topics: Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Bridged-Ring Compounds; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Convulsants; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; High-Throughput Screening Assays; Hippocampus; Mice; Mice, Inbred C57BL; Microelectrodes; Neurons; Picrotoxin; Pregnanolone; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence; Time Factors | 2012 |
Vestibular-mediated synaptic inputs and pathways to sympathetic preganglionic neurons in the neonatal mouse.
Topics: Animals; Animals, Newborn; Bicuculline; Brain Stem; Calcium Signaling; Convulsants; GABA Antagonists; GABA-A Receptor Antagonists; Glycine Agents; Mephenesin; Mice; Mice, Inbred ICR; Motor Neurons; Muscle Relaxants, Central; Neurons; Picrotoxin; Reaction Time; Spinal Cord; Strychnine; Sympathetic Nervous System; Synaptic Potentials; Vestibulocochlear Nerve | 2012 |
Bicuculline- and neurosteroid-sensitive tonic chloride current in rat hypoglossal motoneurons and atypical dual effect of SR95531.
Topics: Action Potentials; Animals; Bicuculline; Brain Stem; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Motor Neurons; Picrotoxin; Pregnanolone; Protein Subunits; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A | 2013 |
Picrotoxin but not bicuculline partially abolishes the cardio-inhibitory responses induced by visual stimulation in the crab Neohelice granulata.
Topics: Animals; Bicuculline; Brachyura; Data Interpretation, Statistical; Electrodes, Implanted; Environment; GABA Antagonists; Heart; Heart Arrest; Heart Rate; Male; Microinjections; Photic Stimulation; Picrotoxin | 2013 |
Ethanol reduces neuronal excitability of lateral orbitofrontal cortex neurons via a glycine receptor dependent mechanism.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine Agents; In Vitro Techniques; Male; Mice; Neurons; Picrotoxin; Prefrontal Cortex; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Strychnine | 2013 |
Multiphasic on/off pheromone signalling in moths as neural correlates of a search strategy.
Topics: Animals; Appetitive Behavior; Bicuculline; Male; Models, Neurological; Moths; Neurons; Pheromones; Picrotoxin; Potassium Channels, Calcium-Activated; Reproducibility of Results | 2013 |
GABA heteroreceptors modulate noradrenaline release in human dental pulp.
Topics: Baclofen; Bicuculline; Chloride Channels; Dental Pulp; Dose-Response Relationship, Drug; Electric Stimulation; Female; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Humans; Male; Morpholines; Norepinephrine; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Sympathetic Nervous System; Sympathomimetics; Time Factors; Tissue Culture Techniques; Tritium; Young Adult | 2013 |
Amyloid β peptide (25-35) in picomolar concentrations modulates the function of glycine receptors in rat hippocampal pyramidal neurons through interaction with extracellular site(s).
Topics: Action Potentials; Amyloid beta-Peptides; Animals; Bicuculline; Cells, Cultured; Dose-Response Relationship, Drug; GABA Antagonists; Glycine Agents; Hippocampus; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glycine; Strychnine | 2014 |
Anesthetic agent-specific effects on synaptic inhibition.
Topics: Anesthesiology; Anesthetics; Animals; Barbiturates; Bicuculline; CA1 Region, Hippocampal; Data Interpretation, Statistical; Dendrites; Dose-Response Relationship, Drug; Evoked Potentials; GABA Antagonists; In Vitro Techniques; Kinetics; Male; Neural Inhibition; Patch-Clamp Techniques; Pharmaceutical Solutions; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 2014 |
GABAB, not GABAA receptors play a role in cortical postictal refractoriness.
Topics: Animals; Azepines; Bicuculline; Cerebral Cortex; Electric Stimulation; Electrodes, Implanted; Epilepsy; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Pentylenetetrazole; Picrotoxin; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 2015 |
High-frequency electrical stimulation suppresses cholinergic accumbens interneurons in acute rat brain slices through GABA(B) receptors.
Topics: Acetylcholine; Action Potentials; Animals; Bicuculline; Cholinergic Neurons; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Interneurons; Male; Nucleus Accumbens; Picrotoxin; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, Muscarinic; Small-Conductance Calcium-Activated Potassium Channels; Tissue Culture Techniques | 2014 |
Dopamine directly modulates GABAA receptors.
Topics: Amino Acid Sequence; Animals; Bicuculline; Cells, Cultured; Corpus Striatum; Dopamine; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; HEK293 Cells; Humans; Male; Molecular Sequence Data; Mutation; Neurons; Picrotoxin; Protein Binding; Protein Subunits; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc | 2015 |
Bud extracts from Tilia tomentosa Moench inhibit hippocampal neuronal firing through GABAA and benzodiazepine receptors activation.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Plant Extracts; Receptors, GABA-A; Tilia | 2015 |
Differential Effects of D-Cycloserine and ACBC at NMDA Receptors in the Rat Entorhinal Cortex Are Related to Efficacy at the Co-Agonist Binding Site.
Topics: Algorithms; Amino Acids, Cyclic; Animals; Astrocytes; Bicuculline; Binding Sites; Cycloserine; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Male; Neurons; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Strychnine | 2015 |
Activation of synaptic and extrasynaptic glycine receptors by taurine in preoptic hypothalamic neurons.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Glycine Agents; In Vitro Techniques; Mice; Neurons; Picrotoxin; Preoptic Area; Pyridazines; Receptors, Glycine; Strychnine; Synapses; Taurine | 2015 |
Functional alterations of the dopaminergic and glutamatergic systems in spontaneous α-synuclein overexpressing rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Synuclein; Animals; Animals, Newborn; Bicuculline; Cell Count; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-B Receptor Agonists; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Mesencephalon; Patch-Clamp Techniques; Picrotoxin; Rats; Synaptic Potentials; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2017 |
Nicotine facilitates synaptic depression in layer V pyramidal neurons of the mouse insular cortex.
Topics: Animals; Bicuculline; Cerebral Cortex; Female; GABA-A Receptor Antagonists; Long-Term Synaptic Depression; Male; Mice; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Synaptic Transmission | 2018 |
GABA
Topics: Allosteric Regulation; Alprazolam; Benzodiazepines; Bicuculline; Binding, Competitive; Cryoelectron Microscopy; Diazepam; GABA Modulators; Humans; Ligands; Models, Molecular; Nanostructures; Picrotoxin; Receptors, GABA-A; Signal Transduction | 2019 |
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A | 2020 |
GABA
Topics: Acids; Animals; Bicuculline; Caffeine; Cyclohexenes; Disease Models, Animal; Electroencephalography; Flavonoids; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Humulus; Hypnotics and Sedatives; Mice; Picrotoxin; Propiophenones; Receptors, GABA-A; Sleep; Sleep Initiation and Maintenance Disorders; Terpenes | 2021 |
Structure and dynamics of differential ligand binding in the human ρ-type GABA
Topics: Bicuculline; Binding Sites; gamma-Aminobutyric Acid; Humans; Ligands; Picrotoxin; Receptors, GABA-A | 2023 |