picrotoxin has been researched along with 4-aminopyridine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.38) | 18.7374 |
| 1990's | 12 (37.50) | 18.2507 |
| 2000's | 10 (31.25) | 29.6817 |
| 2010's | 7 (21.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bijak, M; Brunner, H; Misgeld, U | 1 |
| Aram, JA; Michelson, HB; Wong, RK | 1 |
| Gustafsson, B; Hess, G | 1 |
| Misgeld, U; Müller, W | 1 |
| Markus, H; Pomeranz, B | 1 |
| Brailowsky, S; Knight, RT | 1 |
| Bagust, J; Forsythe, ID; Kerkut, GA; Loots, JM | 1 |
| Bijak, M; Misgeld, U | 2 |
| Michelson, HB; Wong, RK | 1 |
| Bijak, M; Demmelhuber, J; Jarolimek, W; Misgeld, U | 1 |
| Colling, SB; Jefferys, JG; Traub, RD | 1 |
| Kaila, K; Lamsa, K | 1 |
| Balestra, M; Borrelli, AR; Cramer, CL; Eismann, MS; Freedman, LR; Hudzik, TJ; Knowles, MK; Mahmood, N; McCarthy, DJ; Murray, RJ; Palmer, GC; Stagnitto, ML | 1 |
| Albuquerque, EX; Braga, MF; Pereira, EF | 1 |
| Okada, YC; Wu, J | 1 |
| Wong, M; Yamada, KA | 1 |
| Saggau, P; Sinha, SR | 1 |
| Benardo, LS; Yang, L | 1 |
| Liu, X; Stan Leung, L | 1 |
| Gruhn, M; Guckenheimer, J; Harris-Warrick, RM; Land, B | 1 |
| Faber, ES; Sah, P | 1 |
| Errington, AC; Lees, G; Stöhr, T | 1 |
| Inoue, H; Okada, Y | 1 |
| Avoli, M; Biagini, G; D'Antuono, M; Gotman, J; Köhling, R; Ricalzone, S | 1 |
| Sun, QQ | 1 |
| Chavis, P; Farrugia, F; Garenne, A; Le Masson, G; Manzoni, OJ; Marsicano, G; Piet, R | 1 |
| Kirik, D; Kokaia, M; Ledri, M; Madsen, MG; Nikitidou, L | 1 |
| Avoli, M; Benini, R; D'Antuono, M; de Guzman, P; Köhling, R | 1 |
| Heidarinejad, M; Inoue, T; Murata, N; Nakamura, H; Shafeghat, N | 1 |
| Baines, RA; Fan, YN; Masullo, L; Streit, AK | 1 |
| da Rosa, MS; Gonçalves, D; Leipnitz, G; Luft, JG; Morás, AM; Moura, DJ; Pereira, P; Pflüger, PF; Regner, GG; Steffens, L | 1 |
32 other study(ies) available for picrotoxin and 4-aminopyridine
| Article | Year |
|---|---|
Granule cell inhibition and the activity of hilar neurons.
Topics: 4-Aminopyridine; Animals; Axons; Baclofen; Dendrites; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Neural Inhibition; Neural Pathways; Neurons; Picrotoxin; Potassium Channels; Receptors, GABA-A; Synapses | 1992 |
Synchronized GABAergic IPSPs recorded in the neocortex after blockade of synaptic transmission mediated by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Picrotoxin; Quinoxalines; Synapses; Synaptic Transmission | 1991 |
Changes in field excitatory postsynaptic potential shape induced by tetanization in the CA1 region of the guinea-pig hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Receptors, N-Methyl-D-Aspartate; Synapses | 1990 |
Picrotoxin- and 4-aminopyridine-induced activity in hilar neurons in the guinea pig hippocampal slice.
Topics: 4-Aminopyridine; Action Potentials; Animals; Electric Stimulation; Electrophysiology; Guinea Pigs; Hippocampus; Membrane Potentials; Neurons; Picrotoxin | 1991 |
Saphenous has weak ineffective synapses in sciatic territory of rat spinal cord: electrical stimulation of the saphenous or application of drugs reveal these somatotopically inappropriate synapses.
Topics: 4-Aminopyridine; Action Potentials; Afferent Pathways; Aminopyridines; Animals; Denervation; Electric Stimulation; Hindlimb; Peripheral Nerves; Physical Stimulation; Picrotoxin; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Strychnine; Synapses | 1987 |
Inhibitory modulation of cat somatosensory cortex: a pharmacological study.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cats; Evoked Potentials; Evoked Potentials, Somatosensory; Female; gamma-Aminobutyric Acid; Neural Inhibition; Picrotoxin; Somatosensory Cortex; Taurine | 1984 |
Synaptic and non-synaptic components of the dorsal horn potential in isolated hamster spinal cord.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cricetinae; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Spinal Cord; Synapses; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1982 |
Role of glutamatergic synaptic transmission in synchronized discharges of hilar neurons in guinea pig hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Quinoxalines; Receptors, GABA-B; Receptors, Glutamate; Synaptic Transmission; Time Factors | 1993 |
Synchronization of inhibitory neurones in the guinea-pig hippocampus in vitro.
Topics: 4-Aminopyridine; Animals; Baclofen; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Membrane Potentials; Microelectrodes; Neurons; Picrotoxin; Pyramidal Cells; Synaptic Transmission | 1994 |
CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium Channels; Quinoxalines; Synapses | 1993 |
Cellular mechanisms of 4-aminopyridine-induced synchronized after-discharges in the rat hippocampal slice.
Topics: 4-Aminopyridine; Action Potentials; Animals; Hippocampus; Male; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1995 |
Suppression by GABAB receptors of 4-aminopyridine-induced hyperactivity in guinea-pig dentate neurons.
Topics: 4-Aminopyridine; Animals; Bicuculline; Dentate Gyrus; Guinea Pigs; Hippocampus; Membrane Potentials; Picrotoxin; Receptors, GABA-B | 1996 |
Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzolamide; Bicarbonates; Carbonic Anhydrases; Enzyme Inhibitors; Ethoxzolamide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Models, Neurological; Pentobarbital; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 1997 |
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Strychnine; Time Factors; Weaning | 1999 |
Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kinetics; Lead; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channels; Sodium Channels; Synaptic Transmission; Tetrodotoxin | 1999 |
Roles of calcium- and voltage-sensitive potassium currents in the generation of neuromagnetic signals and field potentials in a CA3 longitudinal slice of the guinea-pig.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Electric Stimulation; Electroencephalography; Electromagnetic Fields; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Picrotoxin; Potassium Channels; Tetraethylammonium | 2000 |
Developmental characteristics of epileptiform activity in immature rat neocortex: a comparison of four in vitro seizure models.
Topics: 4-Aminopyridine; Age Factors; Animals; Convulsants; Epilepsy; GABA Antagonists; Magnesium; Membrane Potentials; Neocortex; Organ Culture Techniques; Organophosphorus Compounds; Picrotoxin; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2001 |
Imaging of 4-AP-induced, GABA(A)-dependent spontaneous synchronized activity mediated by the hippocampal interneuron network.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Guinea Pigs; Hippocampus; Interneurons; Neural Pathways; Organ Culture Techniques; Picrotoxin; Receptors, GABA-A | 2001 |
Laminar properties of 4-aminopyridine-induced synchronous network activities in rat neocortex.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Intracellular Membranes; Neocortex; Nerve Net; Picrotoxin; Piperazines; Rats; Rats, Sprague-Dawley | 2002 |
Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Extracellular Space; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Lithium; Male; Neural Conduction; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2004 |
Dopamine modulation of two delayed rectifier potassium currents in a small neural network.
Topics: 4-Aminopyridine; Animals; Cadmium Chloride; Delayed Rectifier Potassium Channels; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Invertebrate; In Vitro Techniques; Membrane Potentials; Nerve Net; Neural Conduction; Neurons; Palinuridae; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Quinidine; Tetraethylammonium; Tetrodotoxin | 2005 |
Independent roles of calcium and voltage-dependent potassium currents in controlling spike frequency adaptation in lateral amygdala pyramidal neurons.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Adrenergic beta-Agonists; Amygdala; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Radiation; Drug Interactions; Elapid Venoms; Electric Stimulation; Female; GABA Antagonists; In Vitro Techniques; Isoproterenol; Male; Methoxyhydroxyphenylglycol; Muscarinic Antagonists; Neurons; Norepinephrine; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Potassium Channel Blockers; Propanolamines; Rats; Rats, Wistar | 2005 |
Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetamides; Animals; Anticonvulsants; Carbamazepine; Convulsants; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Female; In Vitro Techniques; Lacosamide; Male; Membrane Potentials; Patch-Clamp Techniques; Phenobarbital; Picrotoxin; Potassium Channel Blockers; Prohibitins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Visual Cortex | 2006 |
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bumetanide; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycolates; Ion Channels; Mice; Mice, Inbred C57BL; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Nitrobenzoates; Patch-Clamp Techniques; Phloretin; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Quinine; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Somatosensory Cortex; Tetrodotoxin | 2007 |
Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Brain; Carbamazepine; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Entorhinal Cortex; Fructose; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Topiramate; Valproic Acid | 2010 |
Experience-dependent intrinsic plasticity in interneurons of barrel cortex layer IV.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Biotin; Cerebral Cortex; Computer Simulation; Electric Stimulation; Electron Transport Complex IV; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mice; Mice, Transgenic; Models, Neurological; Neuronal Plasticity; Parvalbumins; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Probability; Quinoxalines; Sensory Deprivation; Synaptic Transmission; Vesicular Glutamate Transport Protein 2; Vibrissae | 2009 |
State-dependent, bidirectional modulation of neural network activity by endocannabinoids.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Brain; Cannabinoid Receptor Modulators; Cells, Cultured; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Piperidines; Potassium Channel Blockers; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sodium Channel Blockers; Tetrodotoxin; Valine | 2011 |
Global optogenetic activation of inhibitory interneurons during epileptiform activity.
Topics: 4-Aminopyridine; Animals; Channelrhodopsins; Female; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Interneurons; Luminescent Proteins; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Optogenetics; Parvalbumins; Picrotoxin; Potassium Channel Blockers; Red Fluorescent Protein; Sesterterpenes; Time Factors | 2014 |
Hypersynchronous ictal onset in the perirhinal cortex results from dynamic weakening in inhibition.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cations, Monovalent; Cerebral Cortex; Excitatory Amino Acid Antagonists; GABA Antagonists; Neurons; Periodicity; Phosphinic Acids; Picrotoxin; Piperazines; Potassium; Propanolamines; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Seizures; Tissue Culture Techniques | 2016 |
Optical detection of neuron connectivity by random access two-photon microscopy.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Cells, Cultured; Computer Simulation; Electric Stimulation; GABA Antagonists; Hippocampus; Models, Neurological; Nerve Net; Neurons; Optical Imaging; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Rats, Wistar; Synapses; Voltage-Sensitive Dye Imaging | 2016 |
Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds.
Topics: 4-Aminopyridine; Adult; Amines; Animals; Anticonvulsants; Antipain; Calcium; Calmodulin; Central Nervous System; Convulsants; Cyclohexanecarboxylic Acids; Dipyridamole; Drosophila melanogaster; Drosophila Proteins; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Larva; Male; Molecular Imaging; Motor Neurons; Phenytoin; Picrotoxin; Primary Cell Culture; Sodium Channels | 2016 |
Rosmarinic acid improves oxidative stress parameters and mitochondrial respiratory chain activity following 4-aminopyridine and picrotoxin-induced seizure in mice.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Antioxidants; Behavior, Animal; Cinnamates; Depsides; Disease Models, Animal; DNA Damage; Electron Transport Complex II; Hippocampus; Mice; Mitochondria; Neuroprotective Agents; Oxidative Stress; Picrotoxin; Rosmarinic Acid; Seizures | 2019 |