Page last updated: 2024-08-16

picotamide and aspirin

picotamide has been researched along with aspirin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's7 (38.89)18.2507
2000's6 (33.33)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Liu, XJ; Wang, X; Wang, Y; Zhang, ZH1
de Falco, FA; Mastroroberto, G; Montariello, A; Visconti, OS1
Cattaneo, M; Lecchi, A; Mannucci, PM; Tenconi, PM1
Alberti, P; Corona, C; Gresele, P; Nenci, GG1
Feldhoff, CM; Gresele, P; Pieters, G; Vermylen, J1
Alessandri, C; Balsano, F; Ghiselli, A; Iuliano, L; Praticò, D; Violi, F1
Castiglioni, C; Gazzaniga, PP; Parisi, S; Pignatelli, P; Pulcinelli, FM; Riondino, S1
Boddi, M; Gensini, GF; Gori, AM; Ieri, A; Margheri, M; Martini, F; Modesti, PA; Neri Serneri, GG; Poggesi, L; Rostagno, C1
Ambrosio, G; Chiariello, M; Golino, P; Gresele, P; Leproux, GB; Pascucci, I; Ragni, M; Russolillo, E1
Berrettini, M; De Cunto, M; Nenci, GG; Orzalesi, G; Romanelli, A; Volpato, I1
Corsini, G; Milani, M; Vetrano, A1
Ballerio, R; Buccellati, C; Casagrande, C; Ciceri, P; Folco, G; Nicosia, S1
Gresele, P; Migliacci, R1
Coccheri, S; Marubini, E; Neri Serneri, GG; Violi, F1
Hiatt, WR; Krantz, MJ1
Hackam, DG1
Liu, XJ; Meng, X; Shi, TE; Wang, X; Wei, TT1

Reviews

1 review(s) available for picotamide and aspirin

ArticleYear
Masterclass series in peripheral arterial disease. Antiplatelet therapy for peripheral arterial disease and claudication.
    Vascular medicine (London, England), 2006, Volume: 11, Issue:1

    Topics: Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Humans; Intermittent Claudication; Lower Extremity; Meta-Analysis as Topic; Peripheral Vascular Diseases; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Ticlopidine

2006

Trials

4 trial(s) available for picotamide and aspirin

ArticleYear
[Clinical efficacy of picotamide].
    La Clinica terapeutica, 1991, Jul-15, Volume: 138, Issue:1

    Topics: Adult; Aged; Aspirin; Brain Ischemia; Cerebrovascular Disorders; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Phthalic Acids

1991
The role of extraplatelet thromboxane A2 in unstable angina investigated with a dual thromboxane A2 inhibitor: importance of activated monocytes.
    Coronary artery disease, 1994, Volume: 5, Issue:2

    Topics: Aged; Angina Pectoris; Angina, Unstable; Aspirin; Double-Blind Method; Female; Follow-Up Studies; Humans; Leukocytes, Mononuclear; Lymphocytes; Male; Middle Aged; Myocardial Ischemia; Phthalic Acids; Placebos; Platelet Aggregation Inhibitors; Prospective Studies; Thromboxane A2

1994
Effects of aspirin or picotamide, an antithromboxane agent, in combination with low-intensity oral anticoagulation in patients with acute myocardial infarction: a controlled randomized pilot trial.
    Giornale italiano di cardiologia, 1999, Volume: 29, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anticoagulants; Aspirin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Phthalic Acids; Pilot Projects; Platelet Aggregation Inhibitors; Single-Blind Method; Thromboxanes

1999
Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID study.
    European heart journal, 2004, Volume: 25, Issue:20

    Topics: Adult; Aged; Aspirin; Diabetic Angiopathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Phthalic Acids; Platelet Aggregation Inhibitors; Risk Factors; Survival Analysis; Thromboxane A2

2004

Other Studies

13 other study(ies) available for picotamide and aspirin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Synthesis, in vitro cytotoxicity and biological evaluation of twenty novel 1,3-benzenedisulfonyl piperazines as antiplatelet agents.
    Bioorganic & medicinal chemistry, 2021, 09-15, Volume: 46

    Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Fibroblasts; Mice; Molecular Structure; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship

2021
In vitro effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production.
    Thrombosis research, 1991, Jun-15, Volume: 62, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Drug Interactions; Female; Humans; Male; Malondialdehyde; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Sulfonamides; Thromboxane B2

1991
Picotamide protects mice from death in a pulmonary embolism model by a mechanism independent from thromboxane suppression.
    Thrombosis and haemostasis, 1990, Aug-13, Volume: 64, Issue:1

    Topics: Animals; Aspirin; Disease Models, Animal; Epoprostenol; Male; Mice; Phthalic Acids; Platelet Aggregation Inhibitors; Platelet Count; Pulmonary Embolism; Thromboxane B2

1990
Acetylsalicylic acid, BM 13.177 and picotamide improve the survival of endotoxin-infused rabbits.
    Thrombosis research, 1988, Dec-01, Volume: 52, Issue:5

    Topics: Animals; Aspirin; Endotoxins; Female; Imidazoles; Male; Methylprednisolone; Phthalic Acids; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Thromboxane-A Synthase

1988
Inhibition by picotamide of thromboxane production in vitro and ex vivo.
    European journal of clinical pharmacology, 1988, Volume: 33, Issue:6

    Topics: Adult; Aspirin; Blood Platelets; Female; Humans; In Vitro Techniques; Male; Phthalic Acids; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxane-A Synthase

1988
Effect of picotamide on the calcium mobilization and phospholipase C activation in human platelets.
    Thrombosis research, 1994, Jun-01, Volume: 74, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelets; Calcium; Chromatography, Gel; Enzyme Activation; Humans; In Vitro Techniques; Phthalic Acids; Platelet Activation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Thrombin; Thromboxane A2; Type C Phospholipases

1994
The in vivo antiplatelet effects of thromboxane A2 synthase inhibitors are potentiated by simultaneous thromboxane A2/prostaglandin H2 receptor blockade.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Animals; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Drug Synergism; Epinephrine; Fatty Acids, Unsaturated; Female; Hydrazines; Imidazoles; Male; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxane-A Synthase

1993
[In vitro study of the mechanism of the platelet anti-aggregant action of picotamide (G 137)].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Mar-30, Volume: 59, Issue:3

    Topics: Arachidonic Acid; Aspirin; Blood Platelets; Humans; Malondialdehyde; Molecular Structure; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship; Thromboxane A2; Thromboxane-A Synthase

1983
Evaluation of the effects of anti-thromboxane agents in platelet-vessel wall interaction.
    European journal of pharmacology, 2002, May-17, Volume: 443, Issue:1-3

    Topics: Animals; Aorta, Thoracic; Arachidonic Acid; Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Communication; Dinoprost; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Male; Methacrylates; Muscle Tonus; Muscle, Smooth, Vascular; Phthalic Acids; Platelet Activation; Platelet Aggregation Inhibitors; Rabbits; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase

2002
Picotamide versus aspirin in diabetic patients with peripheral arterial disease: has David defeated Goliath?
    European heart journal, 2004, Volume: 25, Issue:20

    Topics: Arteries; Aspirin; Diabetic Angiopathies; Humans; Peripheral Vascular Diseases; Phthalic Acids; Platelet Aggregation Inhibitors

2004
Medical management of peripheral arterial disease.
    JAMA, 2006, Jul-05, Volume: 296, Issue:1

    Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Humans; Peripheral Vascular Diseases; Phthalic Acids; Platelet Aggregation Inhibitors; Ticlopidine

2006
Synthesis and the Evaluations in vitro Antiplatelet Aggregation Activities of 4-Ethoxyisophthalamides.
    Cardiovascular & hematological agents in medicinal chemistry, 2015, Volume: 13, Issue:2

    Topics: Aspirin; Drug Design; Humans; Inhibitory Concentration 50; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Quantitative Structure-Activity Relationship; Structure-Activity Relationship

2015