Page last updated: 2024-09-05

piboserod and tropisetron

piboserod has been researched along with tropisetron in 4 studies

Compound Research Comparison

Studies (piboserod)	Trials (piboserod)	Recent Studies (post-2010) (piboserod)	Studies (tropisetron)	Trials (tropisetron)	Recent Studies (post-2010) (tropisetron)
119	5	53	944	218	150

Protein Interaction Comparison

Protein	Taxonomy	tropisetron (IC50)
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	3.1623
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	3.1623
Muscarinic acetylcholine receptor M5	Homo sapiens (human)	3.45
Neuronal acetylcholine receptor subunit beta-4	Homo sapiens (human)	1.8
Sodium-dependent serotonin transporter	Homo sapiens (human)	0.488
Neuronal acetylcholine receptor subunit alpha-3	Homo sapiens (human)	1.8

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fischmeister, R; Langlois, M	1
Boulouard, M; Bureau, R; Butt-Gueulle, S; Dauphin, F; Daveu, C; Duchatelle, P; Dumuis, A; Lelong-Boulouard, V; Lemaître, S; Lepailleur, A; Lezoualc'h, F; Pfeiffer, B; Rault, S	1
Endo, T; Hamaue, N; Hirafuji, M; Minami, M	1
Nylander, O; Pihl, L	1

Reviews

2 review(s) available for piboserod and tropisetron

Article	Year
5-HT4 receptor ligands: applications and new prospects. Journal of medicinal chemistry, 2003, Jan-30, Volume: 46, Issue:3 Topics: Animals; Benzamides; Benzimidazoles; Benzoates; Binding Sites; Cardiovascular Physiological Phenomena; Central Nervous System; Digestive System Physiological Phenomena; Humans; Indoles; Ketones; Ligands; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	2003
[Serotonin and anticancer drug-induced emesis]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2004, Volume: 124, Issue:8 Topics: Animals; Antiemetics; Antineoplastic Agents; Cisplatin; Enterochromaffin Cells; Granisetron; Humans; Indoles; Ondansetron; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Tropisetron; Vagus Nerve; Vomiting	2004

Article

Year

5-HT4 receptor ligands: applications and new prospects.

Journal of medicinal chemistry, 2003, Jan-30, Volume: 46, Issue:3

Topics: Animals; Benzamides; Benzimidazoles; Benzoates; Binding Sites; Cardiovascular Physiological Phenomena; Central Nervous System; Digestive System Physiological Phenomena; Humans; Indoles; Ketones; Ligands; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2003

[Serotonin and anticancer drug-induced emesis].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2004, Volume: 124, Issue:8

Topics: Animals; Antiemetics; Antineoplastic Agents; Cisplatin; Enterochromaffin Cells; Granisetron; Humans; Indoles; Ondansetron; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Tropisetron; Vagus Nerve; Vomiting

2004

Other Studies

2 other study(ies) available for piboserod and tropisetron

Article	Year
Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines. Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6 Topics: Animals; Chlorocebus aethiops; COS Cells; Humans; Indoles; Models, Molecular; Molecular Structure; Pyrazines; Radioligand Assay; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sulfonamides	2009
Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine. Acta physiologica (Oxford, England), 2006, Volume: 186, Issue:1 Topics: Anesthetics, Local; Animals; Cyclooxygenase Inhibitors; Duodenum; Granisetron; Indoles; Indomethacin; Intestinal Mucosa; Lidocaine; Male; Ondansetron; Osmotic Pressure; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Tetrodotoxin; Tropisetron	2006

Article

Year

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6

Topics: Animals; Chlorocebus aethiops; COS Cells; Humans; Indoles; Models, Molecular; Molecular Structure; Pyrazines; Radioligand Assay; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sulfonamides

2009

Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine.

Acta physiologica (Oxford, England), 2006, Volume: 186, Issue:1

Topics: Anesthetics, Local; Animals; Cyclooxygenase Inhibitors; Duodenum; Granisetron; Indoles; Indomethacin; Intestinal Mucosa; Lidocaine; Male; Ondansetron; Osmotic Pressure; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Tetrodotoxin; Tropisetron

2006