piboserod has been researched along with piperidines in 38 studies
| Studies (piboserod) | Trials (piboserod) | Recent Studies (post-2010) (piboserod) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 119 | 5 | 53 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (13.16) | 18.2507 |
| 2000's | 16 (42.11) | 29.6817 |
| 2010's | 16 (42.11) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Bingham, S; Ellis, ES; Gaster, LM; Joiner, GF; King, FD; Sanger, GJ; Sutton, JM; Wardle, KA; Wyman, PA | 1 |
| Bingham, S; Ellis, ES; Gaster, LM; Rushant, B; Sanger, GJ; Smith, MI; Wardle, KA | 1 |
| Banner, SE; Sanger, GJ; Smith, MI; Wardle, KA | 1 |
| Banner, SE; Sanger, GJ; Smith, MI | 1 |
| Cooper, SM; Houghton, LA; Jackson, NA; Whorwell, PJ | 1 |
| Kitazumi, K; Sanger, GJ; Yahyah, M; Yoshida, M | 1 |
| Bécamel, C; Bockaert, J; Claeysen, S; Clark, RD; Dumuis, A; Eglen, RM; Sebben, M | 1 |
| Bharucha, AE; Burton, D; Camilleri, M; Cooper, S; Ferber, I; Fitzpatrick, K; Haydock, S; Higgins, R; Tompson, D; Zinsmeister, AR | 1 |
| Fedouloff, M; Hossner, F; Powles, J; Ranson, J; Riley, G; Sanger, G; Voyle, M | 1 |
| Andrade, R; Béïque, JC; Chapin-Penick, EM; Mladenovic, L | 1 |
| Bockaert, J; Charnay, Y; Compan, V; Daszuta, A; Dusticier, N; Hen, R | 1 |
| Ishihara, K; Sasa, M | 1 |
| Kemp, A; Manahan-Vaughan, D | 1 |
| Karaki, S; Kuwahara, A; Mitsui, R; Ono, S | 1 |
| Flevari, PG; Iliodromitis, EK; Kremastinos, DT; Leftheriotis, DI; Livanis, EG; Papalois, A; Poulis, D; Theodorakis, GN | 1 |
| Nylander, O; Pihl, L | 1 |
| Birkeland, JA; Bjørnerheim, R; Brattelid, T; Krobert, KA; Levy, FO; Moberg, ER; Osnes, JB; Qvigstad, E; Sejersted, OM; Sjaastad, I; Skomedal, T | 1 |
| Cachard-Chastel, M; Croes, S; Deloménie, C; Devijver, H; Dewachter, I; Gardier, AM; Langlois, M; Lezoualc'h, F; Sicsic, S; Van Leuven, F | 1 |
| Amano, T; Ariga, H; Ishida, T; Kimura, T; Matsueda, K; Tajiri, H; Torii, A; Uehara, H; Yamato, S | 1 |
| Bornstein, JC; Neal, KB; Parry, LJ | 1 |
| Eda, H; Kimura, N; Komada, T; Mikami, T; Naganeo, R; Nakata, E; Nakatani, K; Ohmi, T; Sakakibara, M; Sugimoto, H; Suzuki, K; Toga, T | 1 |
| Argibay, JA; Bourmeyster, N; Bozon, V; Defamie, N; Derangeon, M; Hervé, JC; Peineau, N; Sarrouilhe, D | 1 |
| Ajdary, S; Ataee, R; Rezayat, M; Shahriari, S; Shokrgozar, MA; Zarrindast, MR | 1 |
| Cornish, JL; Francis, HM; Hunt, LR; Kraushaar, NJ | 1 |
| Andressen, KW; Brudeli, B; Klaveness, J; Krobert, KA; Levy, FO; Moltzau, LR | 1 |
| Andreeva, AV; Fukai, T; Hen, R; Krbanjevic, A; Profirovic, J; Strekalova, E; Urao, N; Ushio-Fukai, M; Varadarajan, S; Voyno-Yasenetskaya, TA | 1 |
| Ballandonne, C; Butt-Gueulle, S; Caignard, DH; Cailly, T; Charnay, Y; Dubost, E; Dulin, F; Dumas, N; Fabis, F; Fossey, C; Magnelli, R; Millet, P; Rault, S; Sopkova de-Oliveira Santos, J | 1 |
| Barrot, M; Bockaert, J; Charnay, Y; Compan, V; Dusticier, N; Jean, A; Laurent, L; Neve, R; Nieoullon, A | 1 |
| Ajjala, DR; Aleti, RR; Bhyrapuneni, G; Kandikere, V; Nirogi, R; Rasheed, MA; Saralaya, R | 1 |
| Cailly, T; Fabis, F; Fontenelle, CQ; Fossey, C; Linclau, B; Wang, Z | 1 |
| Darcet, F; David, DJ; Gardier, AM; Hen, R; Kerdine-Römer, S; Mendez-David, I; Wu, MV | 1 |
| Khakpai, F; Nasehi, M; Tabatabaie, M; Zarrindast, MR | 1 |
| Abboussi, O; El Ganouni, S; Fifel, K; Lakehayli, S; Said, N; Tazi, A | 1 |
| Ebrahimi-Ghiri, M; Farrahizadeh, M; Nasehi, M; Zarrindast, MR | 1 |
| Kim, BJ; Kim, H; Kim, HJ; Lee, GS | 1 |
| Bertero, A; Caboche, J; Catelani, T; Cavaccini, A; De Luca, MA; Giorgi, A; Gozzi, A; Gritti, M; Heck, N; Locarno, A; Margiani, G; Marotta, R; Mereu, M; Migliarini, S; Pasqualetti, M; Tonini, R; Trusel, M | 1 |
| Agrawal, L; Shiga, T; Vimal, SK | 1 |
| Eydipour, Z; Jamaldini, SH; Nasehi, M; Vaseghi, S; Zarrindast, MR | 1 |
2 trial(s) available for piboserod and piperidines
| Article | Year |
|---|---|
5-HT4 receptor antagonism in irritable bowel syndrome: effect of SB-207266-A on rectal sensitivity and small bowel transit.
Topics: Adult; Aged; Catheterization; Colonic Diseases, Functional; Cross-Over Studies; Diarrhea; Double-Blind Method; Female; Gastrointestinal Transit; Humans; Indoles; Intestine, Small; Male; Manometry; Middle Aged; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Rectum; Serotonin Antagonists | 1999 |
Effects of a serotonin 5-HT(4) receptor antagonist SB-207266 on gastrointestinal motor and sensory function in humans.
Topics: Adolescent; Adult; Aldosterone; Digestive System; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Indoles; Male; Middle Aged; Piperidines; Radionuclide Imaging; Sensation; Serotonin Antagonists | 2000 |
36 other study(ies) available for piboserod and piperidines
| Article | Year |
|---|---|
N-[(1-butyl-4-piperidinyl)methyl]-3,4dihydro-2H-[1,3]oxazino[3,2- a]indole10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral activity.
Topics: Administration, Oral; Animals; Dioxanes; Dogs; Guinea Pigs; Indoles; Muscle Contraction; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides | 1995 |
Selective and functional 5-hydroxytryptamine4 receptor antagonism by SB 207266.
Topics: Animals; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Colon; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Indoles; Male; Muscle Contraction; Piperidines; Serotonin; Serotonin Antagonists; Time Factors | 1996 |
SB-207266: 5-HT4 receptor antagonism in human isolated gut and prevention of 5-HT-evoked sensitization of peristalsis and increased defaecation in animal models.
Topics: Administration, Oral; Animals; Defecation; Disease Models, Animal; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Intestinal Diseases; Intestines; Male; Mice; Mice, Inbred Strains; Peristalsis; Piperidines; Serotonin Antagonists | 1998 |
5-HT4 receptor antagonism potentiates inhibition of intestinal allodynia by 5-HT3 receptor antagonism in conscious rats.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Granisetron; Indoles; Male; Pain; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Rectum; Serotonin Antagonists | 1999 |
Increased defecation during stress or after 5-hydroxytryptophan: selective inhibition by the 5-HT(4) receptor antagonist, SB-207266.
Topics: 5-Hydroxytryptophan; Animals; Defecation; Diarrhea; Dose-Response Relationship, Drug; Fasting; Indoles; Male; Mice; Mice, Inbred ICR; Piperidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Restraint, Physical; Serotonin Antagonists; Stress, Psychological | 2000 |
Pharmacological properties of 5-Hydroxytryptamine(4) receptor antagonists on constitutively active wild-type and mutated receptors.
Topics: Adenylyl Cyclases; Allosteric Regulation; Aminobenzoates; Animals; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gs; Humans; Indoles; Mice; Models, Biological; Mutation; para-Aminobenzoates; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Sulfonamides; Transfection | 2000 |
Synthesis and pharmacological activity of metabolites of the 5-HT(4) receptor antagonist SB-207266.
Topics: Animals; Guinea Pigs; Humans; Indoles; Piperidines; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists | 2001 |
Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Bicuculline; Fluorobenzenes; GABA-A Receptor Antagonists; Glutamic Acid; Indoles; Lidocaine; Male; Patch-Clamp Techniques; Phenols; Pindolol; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors | 2004 |
[Feeding disorders in 5-HT4 receptor knockout mice].
Topics: Animals; Anorexia; Appetite; Chromatography, High Pressure Liquid; Corticosterone; Feeding and Eating Disorders; Gene Expression Regulation; Leptin; Limbic System; Male; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Piperidines; Propane; Receptors, Serotonin, 5-HT4; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Stress, Psychological | 2004 |
Failure of repeated electroconvulsive shock treatment on 5-HT4-receptor-mediated depolarization due to protein kinase A system in young rat hippocampal CA1 neurons.
Topics: Aniline Compounds; Animals; Cyclic AMP-Dependent Protein Kinases; Electroshock; Hippocampus; In Vitro Techniques; Male; Neurons; Piperazines; Piperidines; Propane; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Second Messenger Systems; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides | 2004 |
The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo.
Topics: Aniline Compounds; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Motor Activity; Neuronal Plasticity; Piperidines; Propane; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2005 |
Muscarinic and 5-HT4 receptors participate in the regulation of the frequency of spontaneous contractions of the longitudinal muscle in rat distal colon.
Topics: Animals; Atropine; Colon; Dioxanes; Gastrointestinal Motility; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists | 2005 |
The effects of 5-HT4 receptor blockade and stimulation, during six hours of atrial fibrillation.
Topics: Aniline Compounds; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiologic Techniques, Cardiac; Heart Rate; Indoles; Male; Piperidines; Refractory Period, Electrophysiological; Serotonin 5-HT4 Receptor Antagonists; Swine | 2005 |
Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine.
Topics: Anesthetics, Local; Animals; Cyclooxygenase Inhibitors; Duodenum; Granisetron; Indoles; Indomethacin; Intestinal Mucosa; Lidocaine; Male; Ondansetron; Osmotic Pressure; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Tetrodotoxin; Tropisetron | 2006 |
Effects of treatment with a 5-HT4 receptor antagonist in heart failure.
Topics: Adrenergic beta-Agonists; Animals; Cardiac Output; Heart Failure; Indoles; Isoproterenol; Lung; Male; Myocardial Contraction; Myocardium; Organ Size; Piperidines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin, 5-HT4; RNA, Messenger; Serotonin 5-HT4 Receptor Antagonists; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling | 2007 |
5-HT4 receptor agonists increase sAPPalpha levels in the cortex and hippocampus of male C57BL/6j mice.
Topics: Aminobenzoates; Amyloid beta-Protein Precursor; Animals; Benzofurans; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Hippocampus; Indans; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; para-Aminobenzoates; Piperidines; RNA, Messenger; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2007 |
Urocortin I is present in the enteric nervous system and exerts an excitatory effect via cholinergic and serotonergic pathways in the rat colon.
Topics: Animals; Atropine; Colon; Corticotropin-Releasing Hormone; Dioxanes; Electric Stimulation; Enteric Nervous System; Gastrointestinal Motility; Hexamethonium; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Ondansetron; Peptide Fragments; Piperidines; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Tetrodotoxin; Urocortins | 2007 |
Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice.
Topics: Animals; Calbindin 2; Enteric Nervous System; Gastrointestinal Motility; Granisetron; Indoles; Jejunum; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide Synthase Type I; Piperidines; Polymorphism, Genetic; S100 Calcium Binding Protein G; Serotonin; Serotonin Agents; Serotonin Antagonists; Sodium Channel Blockers; Species Specificity; Tetrodotoxin; Tryptophan Hydroxylase | 2009 |
In vitro and in vivo pharmacological characterization of PF-01354082, a novel partial agonist selective for the 5-HT(4) receptor.
Topics: Administration, Oral; Animals; Benzimidazoles; Carbachol; Cell Line; CHO Cells; Cholinergic Agonists; Cricetinae; Cricetulus; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Esophagus; Gastrointestinal Motility; Humans; Indoles; Kidney; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Receptor Agonists; Time Factors | 2009 |
5-HT4 and 5-HT2 receptors antagonistically influence gap junctional coupling between rat auricular myocytes.
Topics: Adenylyl Cyclases; Aminobenzoates; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Connexins; Gap Junctions; Heart Atria; In Vitro Techniques; Indoles; Myocytes, Cardiac; para-Aminobenzoates; Patch-Clamp Techniques; Phosphorylation; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT4; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Sulfonamides | 2010 |
Study of 5HT3 and HT4 receptor expression in HT29 cell line and human colon adenocarcinoma tissues.
Topics: Adenocarcinoma; Aminobenzoates; Biguanides; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Cisapride; Colonic Neoplasms; HT29 Cells; Humans; Oxazines; para-Aminobenzoates; Piperidines; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2010 |
Serotonin 5-HT4 receptors in the nucleus accumbens are specifically involved in the appetite suppressant and not locomotor stimulant effects of MDMA ('ecstasy').
Topics: Animals; Appetite Depressants; Drinking; Eating; Male; Microinjections; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Piperidines; Propane; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists; Weight Loss | 2011 |
Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists.
Topics: Amides; Esters; Humans; Indoles; Ligands; Oxazines; Piperidines; Prodrugs; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists; Structure-Activity Relationship | 2010 |
A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor.
Topics: Aniline Compounds; Animals; Capillaries; Cell Adhesion; Cell Membrane Permeability; Cell Movement; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; GTP-Binding Protein alpha Subunits, G12-G13; Human Umbilical Vein Endothelial Cells; Ischemia; Mice; Muscles; Neovascularization, Physiologic; Piperidines; Propane; Receptors, Serotonin, 5-HT4; Regional Blood Flow; rhoA GTP-Binding Protein; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Wound Healing | 2013 |
Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.
Topics: Animals; Dioxanes; Drug Design; Humans; Iodine Radioisotopes; Ligands; Mice; Molecular Probes; Piperidines; Radioligand Assay; Radiopharmaceuticals; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists; Structure-Activity Relationship; Tomography, Emission-Computed, Single-Photon | 2012 |
The nucleus accumbens 5-HTR₄-CART pathway ties anorexia to hyperactivity.
Topics: Amphetamine; Animals; Anorexia; Cocaine; Hyperkinesis; Male; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Piperidines; Propane; Real-Time Polymerase Chain Reaction; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists | 2012 |
In-vivo rat striatal 5-HT4 receptor occupancy using non-radiolabelled SB207145.
Topics: Aniline Compounds; Animals; Benzofurans; Binding, Competitive; Brain; Drug Discovery; Indoles; Ligands; Male; Oxazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists; Sulfonamides; Tandem Mass Spectrometry; Tissue Distribution | 2013 |
Design of fluorinated 5-HT(4)R antagonists: influence of the basicity and lipophilicity toward the 5-HT(4)R binding affinities.
Topics: Animals; Drug Design; Guinea Pigs; Halogenation; Humans; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists | 2013 |
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Comorbidity; Corticosterone; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Indoles; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides; Time Factors | 2014 |
The effects of CA1 5HT4 receptors in MK801-induced amnesia and hyperlocomotion.
Topics: Amnesia; Aniline Compounds; Animals; CA1 Region, Hippocampal; Dizocilpine Maleate; Drug Partial Agonism; Exploratory Behavior; Male; Memory; Mice; Motor Activity; para-Aminobenzoates; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2015 |
Behavioral effects of D3 receptor inhibition and 5-HT4 receptor activation on animals undergoing chronic cannabinoid exposure during adolescence.
Topics: Aging; Aniline Compounds; Animals; Anxiety; Behavior, Animal; Cannabinoids; Disease Models, Animal; Dopaminergic Neurons; Indans; Male; Memory; Morpholines; Piperidines; Rats, Wistar; Receptors, Dopamine D3; Receptors, Serotonin, 5-HT4; Schizophrenia; Serotonin 5-HT4 Receptor Antagonists | 2016 |
Modulation of cannabinoid signaling by hippocampal 5-HT4 serotonergic system in fear conditioning.
Topics: Aniline Compounds; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoids; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; Memory; Mice; para-Aminobenzoates; Piperidines; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2016 |
Hwangryunhaedok-tang induces the depolarization of pacemaker potentials through 5-HT
Topics: Animals; Biological Clocks; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Drugs, Chinese Herbal; Enzyme Inhibitors; Gastrointestinal Motility; GTP-Binding Proteins; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mice, Inbred ICR; Oxazines; Patch-Clamp Techniques; Phenols; Piperidines; Plant Extracts; Propane; Protein Kinase C; Receptors, Serotonin; rho-Associated Kinases; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides; Thapsigargin | 2017 |
Serotonergic Signaling Controls Input-Specific Synaptic Plasticity at Striatal Circuits.
Topics: Animals; Calcium Signaling; Corpus Striatum; Excitatory Postsynaptic Potentials; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Long-Term Synaptic Depression; Mice; Mice, Transgenic; Neural Pathways; Neuronal Plasticity; Optogenetics; Piperidines; Propane; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides; Synapses; Thalamus | 2018 |
Role of serotonin 4 receptor in the growth of hippocampal neurons during the embryonic development in mice.
Topics: Aniline Compounds; Animals; Axons; Brain-Derived Neurotrophic Factor; Dendrites; Embryo, Mammalian; Gene Knockdown Techniques; Hippocampus; Indoles; Intercellular Signaling Peptides and Proteins; Mice; Nerve Growth Factor; Nerve Growth Factors; Nerve Tissue Proteins; Neurogenesis; Neurons; Piperidines; Receptors, Serotonin, 5-HT4; RNA, Messenger; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides | 2019 |
The role of 5-HT4 serotonin receptors in the CA1 hippocampal region on memory acquisition impairment induced by total (TSD) and REM sleep deprivation (RSD).
Topics: Aniline Compounds; Animals; Avoidance Learning; CA1 Region, Hippocampal; Male; Memory Consolidation; Memory Disorders; Microinjections; Motor Activity; Pain Perception; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sleep Deprivation | 2020 |