phytosterols has been researched along with verticine* in 2 studies
2 other study(ies) available for phytosterols and verticine
| Article | Year |
|---|---|
A novel steroidal alkaloid from Fritillaria shuchengensis.
A novel steroidal alkaloid, suchengbeisine (1), along with two known steroidal alkaloids, N-oxide of verticinone (2) and zhebeininoside (3), were isolated from the bulbs of Fritillaria shuchengensis S. C. Chen et S. F. Yin. The structures of these compounds were elucidated by intensive spectroscopic methods, including NMR, IR, CD and MS. Topics: Alkaloids; Caco-2 Cells; Cell Proliferation; Cell Survival; Cevanes; Dose-Response Relationship, Drug; Fritillaria; HeLa Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Molecular Structure; Phytosterols; Plant Roots; Plants, Medicinal; Steroids | 2013 |
Differentiation-inducing effects of verticinone, an isosteroidal alkaloid isolated from the bulbus of Fritillaria ussuriensis, on human promyelocytic leukemia HL-60 cells.
The inducer of differentiation of human promyelocytic leukemia HL-60 cells is commonly accepted to have potential therapeutic importance. Verticinone, one of the major isosteroidal alkaloids from the bulbus of Fritillaria ussuriensis, was found to inhibit the growth of HL-60 cells by inducing these cells to differentiate toward granulocytes. Importantly, the combination of verticinone with all-trans retinoic acid (ATRA), a well-known inducer of HL-60 cells into granulocytic lineages, was more effective than either alone, suggesting its therapeutic use in minimizing the effective dose of ATRA. Topics: Alkaloids; Cell Differentiation; Cevanes; Fritillaria; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Phytosterols; Plant Extracts; Plant Structures | 2002 |