phytosterols and vanillin

The first phytochemical study of Simira eliezeriana Peixoto (Rubiaceae) allowed the isolation and structural determination of two new diterpenes named simirane A [(5R,6R,8R,9R,10S,11S,13S)-6β,11β-dihydroxy-2,4(18),15-erythroxylatrien-1-one] (1) and simirane B [(5S,8R,9R,10S,11S,13S)-11β-hydroxy-2,4(18),15-erythroxylatrien-1-one] (2), together with seven known compounds: sitosterol (3), stigmasterol (4), campesterol (5), coniferaldehyde (6), vanillin (7), pinoresinol (8) and harman (9) from the bark of the plant. The structures of the compounds were established on the basis of spectroscopic methods, including 1-D and 2-D NMR, HRESI-MS and CD analysis and comparisons with available literature data of known compounds.

Topics: Acrolein; Benzaldehydes; Cholesterol; Diterpenes; Ethanol; Furans; Harmine; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Phytosterols; Plant Bark; Plant Extracts; Rubiaceae; Sitosterols

To investigate the chemical constituents of the root barks of Periploca sepium.. Column chromatographic techniques were used to isolate the chemical constituents. NMR and MS methods were employed for their structural elucidation.. Eight compounds were isolated and identified as isovanillin (1), vanillin (2), 4-methoxysalicylic acid (3), (24R)-9, 19-cycloart-25-ene-3beta, 24-diol (4), (24S)-9, 19-cycloart-25-ene-3beta, 24-diol (5), cycloeucalenol (6), beta-amyrin acetate (7) and alpha-amyrin (8).. Compounds 1-6 were isolated from this plant for the first time.

Topics: Benzaldehydes; Molecular Structure; Periploca; Phytosterols; Plant Bark; Plant Roots; Plants, Medicinal; Triterpenes