phytosterols and ketoprofen-lysine

Piascledine is a plant drug which positively influences the metabolism of cartilage and bone tissues. The authors studied the therapeutic effect of the drug in outpatients with chronic nonspecific dorsalgia. Piascledine was administered in dose 300 mg daily during two months. In the first month, it was used in the combination with artrosilene (320 mg daily). A comparison group included patients receiving monotherapy with NSAIDs (artrosilene). The study confirmed the high analgesic efficacy of piascledine in the treatment of patients with chronic nonspecific dorsalgia with controlled using of NSAIDs. The positive effect of piascledine was demonstrated after one month of treatment. The authors suggest that further clinical trials and placebo-control studies are needed to confirm these results.

Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Drug Combinations; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Phytosterols; Plant Extracts; Vitamin E

To study the efficacy and safety of artrosilene in the combination with piascledine in patients with low-back pain.. Sixty patients, 42 women and 18 men (mean age 53,6±10,4 years) with chronic nonspecific low-back pain were treated with artrosilene (ketoprofen lysine salt) in the combination with the chondro protector piascledine (a mix of avocado and soybean oil extracts).. There the persistent decrease in the intensity of pain syndrome and severity of vertebral syndrome and improvement of quality of life.. The drugs can be recommended for treatment of nonspecific low-back pain.

Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Therapy, Combination; Female; Humans; Ketoprofen; Low Back Pain; Lysine; Male; Middle Aged; Phytosterols; Plant Extracts; Treatment Outcome; Vitamin E