phytosterols and 5-6-epoxycholesterol

Cholesterol oxidation products have an established proatherogenic and cytotoxic effect. An increased exposure to these substances may be associated with the development of atherosclerosis and cancers. Relatively little, though, is known about the effect of phytosterol oxidation products, although phytosterols are present in commonly available and industrial food products. Thus, the aim of the research was to assess the effect of 5. The animals were divided into 3 groups and exposed to nutritional sterols by receiving feed containing 5. During the experiment, the levels of lipid peroxidation products increased, such as CD and anti-7-ketocholesterol antibodies. At the same time, the plasma levels of FRAP and serum activity of PON1 decreased alongside the reduced activity of GPx, GR, and SOD in RBCs. There was no effect of the studied compounds on the plasma MDA levels or on the activity of CAT and GST in RBCs.. Both 5

Topics: Animals; Antibodies; Antioxidants; Aryldialkylphosphatase; Catalase; Cholesterol; Diet; Erythrocytes; Glutathione Peroxidase; Glutathione Reductase; Ketocholesterols; Male; Malondialdehyde; Oxidative Stress; Phytosterols; Rats; Rats, Wistar; Superoxide Dismutase