phytoestrogens has been researched along with 5-6-11-12-17-18-hexahydrocyclononatriindole* in 1 studies
1 other study(ies) available for phytoestrogens and 5-6-11-12-17-18-hexahydrocyclononatriindole
Article | Year |
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Convenient synthesis of 5,6,11,12,17,18- hexahydrocyclononal[1,2-b:4,5-b':7,8-b'']triindole, a novel phytoestrogen.
An efficient one-pot synthesis is described of 5,6,11,12,17,18-hexahydrocyclononal[1,2-b:4,5-b':7,8-b'']triindole (CTr), a potent estrogen agonist from food plants. For the procedure, gramine is treated with dimethyl sulfate and sodium in ethanol at room temperature. Quenching of the reaction with water and workup of the product provides CTr in approximately 75% yield. Topics: Brassica; Catalysis; Estrogens, Non-Steroidal; Indoles; Isoflavones; Magnetic Resonance Spectroscopy; Molecular Structure; Phytoestrogens; Plant Preparations; Receptors, Estrogen; Structure-Activity Relationship; Temperature; Water | 2003 |