Page last updated: 2024-09-04

phyllodulcin, (r)-isomer and warfarin

phyllodulcin, (r)-isomer has been researched along with warfarin in 10 studies

Compound Research Comparison

Studies
(phyllodulcin, (r)-isomer)
Trials
(phyllodulcin, (r)-isomer)
Recent Studies (post-2010)
(phyllodulcin, (r)-isomer)
Studies
(warfarin)
Trials
(warfarin)
Recent Studies (post-2010) (warfarin)
210336,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomyphyllodulcin, (r)-isomer (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's5 (50.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akada, Y; Gotoh, M; Kawano, S; Tanase, Y1
Chatani, N; Murakami, N; Uchida, E; Yamahara, J; Yoshikawa, M1
Hagiwara, Y; Hashimoto, Y; Konishi, T; Kurokawa, N; Tachibana, Y1
Kawai, K; Nakajima, S; Nozawa, K; Tsuda, Y; Yamada, M1
Kim, SH; Kim, SJ; Shin, JM; Shin, W1
Chatani, N; Harada, E; Murakami, N; Nishino, Y; Yamahara, J; Yoshikawa, M1
Matsuda, H; Shimoda, H; Yoshikawa, M1
Matsuda, H; Shimoda, H; Yamahara, J; Yoshikawa, M1
Kagata, M; Kawamura, M; Masaki, E; Nishi, H1
Kayaba, S; Nakazawa, T; Ohsawa, K; Takahashi, K; Yasuda, T1

Other Studies

10 other study(ies) available for phyllodulcin, (r)-isomer and warfarin

ArticleYear
[High-speed liquid chromatographic analysis of drugs. IV. Speration analysis of phyllodulcin and hydrangenol in sweet hydrangea (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1979, Volume: 99, Issue:6

    Topics: Benzopyrans; Chromatography, High Pressure Liquid; Coumarins; Isocoumarins

1979
Thunberginols A, B, and F, new antiallergic and antimicrobial principles from hydrangeae dulcis folium.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae; Benzofurans; Benzopyrans; Benzoquinones; Bronchoconstriction; Coumarins; Guinea Pigs; In Vitro Techniques; Isocoumarins; Microbial Sensitivity Tests; Passive Cutaneous Anaphylaxis; Plant Extracts; Plants, Medicinal

1992
[The quantitative analysis of phyllodulcin in "Amacha" (sweet hydrangea) by means of thin-layer chromatography (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1974, Volume: 94, Issue:9

    Topics: Chromatography, Thin Layer; Coumarins; Isocoumarins; Plants

1974
Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds.
    Chemical & pharmaceutical bulletin, 1981, Volume: 29, Issue:9

    Topics: Antifungal Agents; Coumarins; Isocoumarins

1981
Structure-taste correlations in sweet dihydrochalcone, sweet dihydroisocoumarin, and bitter flavone compounds.
    Journal of medicinal chemistry, 1995, Oct-13, Volume: 38, Issue:21

    Topics: Chalcone; Chalcones; Chemical Phenomena; Chemistry, Physical; Coumarins; Crystallization; Crystallography, X-Ray; Flavones; Flavonoids; Isocoumarins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship; Sweetening Agents; Taste; Thermodynamics

1995
[Quantitative analysis of dihydroisocoumarin constituents of Hydrangeae Dulcis Folium by means of high performance liquid chromatography. Chemical characterization of the processing, distribution in plant, and seasonal fluctuation].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1994, Volume: 114, Issue:3

    Topics: Benzopyrans; Chromatography, High Pressure Liquid; Coumarins; Isocoumarins; Japan; Plant Extracts; Plants, Medicinal; Seasons

1994
Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:7

    Topics: Animals; Antigen-Antibody Reactions; Benzofurans; Benzopyrans; Bibenzyls; Calcimycin; Coumarins; Histamine Release; Immunoglobulin E; Inhibitory Concentration 50; Ionophores; Isocoumarins; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneum; Phenols; Phthalic Acids; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar; Stilbenes; Structure-Activity Relationship

1999
Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:8

    Topics: Animals; Benzofurans; Benzopyrans; Coumarins; Glucosides; Isocoumarins; Male; Passive Cutaneous Anaphylaxis; Plants, Medicinal; Rats; Rats, Wistar

1999
Phyllodulcin, a constituent of "Amacha", inhibits phosphodiesterase in bovine adrenocortical cells.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:2

    Topics: Adrenal Cortex; Animals; Cattle; Cells, Cultured; Coumarins; Hydrangea; Isocoumarins; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases

2002
Metabolic fate of orally administered phyllodulcin in rats.
    Journal of natural products, 2004, Volume: 67, Issue:9

    Topics: Administration, Oral; Animals; Bacitracin; Benzopyrans; Coumarins; Feces; Hydrangea; Isocoumarins; Kanamycin; Liver; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Sulfathiazoles; Tetracycline; Urine

2004