phosphotyrosine has been researched along with vanadates in 236 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (5.93) | 18.7374 |
| 1990's | 147 (62.29) | 18.2507 |
| 2000's | 64 (27.12) | 29.6817 |
| 2010's | 8 (3.39) | 24.3611 |
| 2020's | 3 (1.27) | 2.80 |
| Authors | Studies |
|---|---|
| Bixby, JL; Jhabvala, P | 1 |
| Bailey, TL; Burns, C; McVicar, DW; O'Shea, JJ; Smyth, MJ | 1 |
| Chou, MM; Fajardo, JE; Hanafusa, H | 1 |
| Green, SP; Hamilton, JA; Phillips, WA | 1 |
| Heffetz, D; Rutter, WJ; Zick, Y | 1 |
| Barbacid, M; Jing, S; Tapley, P | 1 |
| Boulet, I; Dunn, AR; Green, SP; Lock, P; Phillips, WA; Ralph, S; Stanley, E | 1 |
| Ballotti, R; Filloux, C; Scimeca, JC; Van Obberghen, E | 1 |
| Kume, T; Oishi, M; Watanabe, T | 1 |
| Hadari, YR; LeRoith, D; Nadiv, O; Roberts, CT; Rothenberg, P; Tzahar, E; Yarden, Y; Zick, Y | 1 |
| Calas, B; Chavanieu, A; Grigorescu, F; Vaglio, P | 1 |
| Chiang, TM | 1 |
| Furuya, W; Grinstein, S; Lu, DJ; Mills, GB | 1 |
| Howard, BD; Zhong, XH | 1 |
| Dutta, A; Hamaguchi, M; Hanafusa, H | 1 |
| Downey, GP; Grinstein, S; Pâquet, MR; Trudel, S | 1 |
| Cruz, TF; Kandel, RA; Mills, G; Pritzker, KP | 1 |
| Geladopoulos, TP; Sotiroudis, TG | 1 |
| Brown, AB; Chan, TM; Chen, YX; Jeng, Y; Tatoyan, A; Yang, DC | 1 |
| Azzi, L; Meijer, L; Wang, JY | 1 |
| Akiyama, T; Oishi, K; Tsukita, S; Yamamoto, T; Yamanashi, Y | 1 |
| Deans, J; Ledbetter, JA; Parsons, M; Schieven, GL; Valentine, M | 1 |
| Grinstein, S; Pâquet, MR; Trudel, S | 1 |
| DiGiovanna, MP; Sartorelli, AC | 1 |
| Rozengurt, E; Sinnett-Smith, J; Zachary, I | 1 |
| Bourassa, C; Chevalier, S; Durocher, Y; Nguyen, LT; Roberts, KD | 1 |
| Kaplan, NO; Knowles, AF; Leis, JF | 1 |
| Klarlund, JK | 1 |
| Courtneidge, SA | 1 |
| Blumenthal, DK; Chan, CP; Gallis, B; Krebs, EG; Pallen, CJ; Wang, JH | 1 |
| Bauer, H; Niemann, H; Simon, E; Snoek, GT; Tamura, T | 1 |
| Gentleman, S; Martensen, TM; Reid, TW | 1 |
| Bolen, JB; DeSeau, V; Rosen, N | 1 |
| Comoglio, PM; D'Urso, N; Giancotti, FG; Marchisio, PC; Tarone, G | 1 |
| Bernier, M; Laird, DM; Lane, MD | 1 |
| Bordwell, KL; Casnellie, JE; Luhowskyj, S; Mooney, RA | 1 |
| Anderson, DL; Mooney, RA | 1 |
| Beach, D; Draetta, G; Morla, AO; Wang, JY | 1 |
| Maher, PA | 1 |
| Berruti, G; Martegani, E | 1 |
| Araki, S; Ishibashi, S; Oishi, H; Okamura, N; Saeki, S; Yamaguchi, M; Yamane, H | 1 |
| Oliver, JM; Pfeiffer, JR | 1 |
| Auberger, P; Farahi Far, D; Imbert, V; Mari, B; Peyron, JF; Rossi, B | 1 |
| Earp, HS; Huckle, WR | 1 |
| Errasfa, M; Stern, A | 1 |
| Ahmad, F; Deragon, G; Fantus, IG | 1 |
| Goldman, R; Zor, U | 1 |
| Cruz, TF; Grima, DT; Kandel, RA; Pepinsky, B | 1 |
| Kataoka, H; Makita, M; Nakai, K | 1 |
| Collares-Buzato, CB; Hirst, BH; Jepson, MA; McEwan, GT; Simmons, NL | 1 |
| Buensuceso, C; Mahadevan, L; Montague, F; Rogers, MV | 1 |
| Khandelwal, RL; Pugazhenthi, S | 1 |
| Ikebuchi, H; Nakanishi, M; Sawada, J; Teshima, R | 1 |
| Rieber, M; Rieber, MS | 1 |
| Atfi, A; Boissonneault, M; Chapdelaine, A; Chevalier, S; Drobetsky, E | 1 |
| Ahmad, S; Hollenberg, MD; Laniyonu, A; Saifeddine, M | 1 |
| Doki, Y; Inoue, M; Iwazawa, T; Kadowaki, T; Matsui, S; Oka, H; Shimaya, K; Shiozaki, H; Takeichi, M; Tamura, S | 1 |
| Agostini, E; Aiuti, A; Aiuti, F; Dianzani, F; Giovannetti, A; Oliva, A; Pandolfi, F; Pierdominici, M; Pizzoli, PM | 1 |
| Kim, G; Yurkow, EJ | 1 |
| Avallone, A; D'Alto, V; Fattore, M; Florio, T; Meucci, O; Schettini, G; Scorziello, A | 1 |
| Bordin, L; Clari, G; Dalla Vecchia, F; Moret, V; Moro, I | 1 |
| Kondo, Y; Kusaka, J; Sato, M; Tsujimoto, H; Yoshida, H; Yura, Y | 1 |
| Feghali, CA; Wright, TM | 1 |
| Mire-Sluis, A; Page, LA; Thorpe, R; Wadhwa, M | 1 |
| Jones, PM; Persaud, SJ; Wheeler-Jones, CP | 1 |
| Hamaguchi, T; Osada, H; Sudo, T | 1 |
| Furuya, Y; Mashima, K | 1 |
| Hamburger, AW; Mishra, S | 1 |
| Chao, W; Liu, H; Olson, MS | 1 |
| Rapp, UR; Reed, JC; Tonks, NK; Turner, BC | 1 |
| Atkinson, TP; Hohman, RJ; Lee, CW; Rhee, SG | 1 |
| Birge, RB; Cantley, LC; Fajardo, JE; Hanafusa, H; Reichman, C; Shoelson, SE; Songyang, Z | 1 |
| Di Salvo, J; Lauer, J; Semenchuk, LA | 1 |
| Davis, JP; Van Etten, RL; Zhou, MM | 1 |
| Aharoni, D; Amsterdam, A; Dantes, A | 1 |
| de Jonge, HR; Edixhoven, MJ; Tertoolen, LG; Tilly, BC; van den Berghe, N | 1 |
| Beaven, MA; Santini, F | 1 |
| Funayama, A; Katoh, S; Kohno, H; Ohkubo, Y | 1 |
| Dombrádi, V; Ferber, E; Gergely, P; Goldman, R; Szücs, K; Zor, U | 1 |
| Greenwel, P; Hu, W; Kohanski, RA; Ramirez, F | 1 |
| Burns, DM; Kawase, T; Ogata, S; Orikasa, M | 1 |
| Amino, N; Liu, G; Sumizaki, H; Takano, T | 1 |
| Dufour, M; Faure, R; Posner, BI; Shaver, A; Vincent, M | 1 |
| Bronte, V; Collavo, D; Macino, B; Mandruzzato, S; Rosato, A; Zambon, A; Zanovello, P | 1 |
| Bolen, JB; Brumell, JH; Burkhardt, AL; Grinstein, S | 1 |
| Edwards, SW; Galvani, DW; Lowe, GM; Slupsky, JR | 1 |
| Aguie-Aguie, G; Haye, B; Martiny, L; Petitfrere, E; Sartelet, H | 1 |
| Danielsen, AG; Ogawa, W; Roth, RA; Yeh, TC | 1 |
| Heidenreich, KA; Kummer, JL | 1 |
| Pfefferkorn, LC; Swink, SL | 1 |
| Dilts, CA; Ethier, SP; Kokeny, KE; Ridings, JW | 1 |
| Eriksson, JW; Lönnroth, P; Posner, BI; Shaver, A; Smith, UP; Wesslau, C | 1 |
| Barrett, T; Davis, RJ; Galcheva-Gargova, Z; Klier, FG; Konstantinov, KN; Wu, IH | 1 |
| Deyama, Y; Hisada, Y; Matsumoto, A; Okamoto, T; Suzuki, K; Yoshimura, Y | 1 |
| Henquin, JC; Jonas, JC | 1 |
| Hallett, MB; Lloyds, D; Neville, N | 1 |
| Alberta, JA; Bhattacharyya, A; Kaplan, DR; Rua, LA; Segal, RA; Stephens, RM; Stiles, CD | 1 |
| Epstein, R; Gulliford, T; Huang, GC; Ouyang, X; Zhang, H | 1 |
| Hudson, LD; Ranjan, M | 1 |
| Jänne, OA; Palvimo, JJ; Reinikainen, P | 1 |
| Frey, T; Ledbetter, JA; Lund-Johansen, F; Thompson, PA | 1 |
| Bonjour, JP; Caverzasio, J; Palmer, G | 1 |
| Assreuy, J; Borges, VM; Cunha e Silva, NL; de Souza, W; Martiny, A; Meyer-Fernandes, JR; Vannier-Santos, MA | 1 |
| Fan, R; García-Cardeña, G; Liu, J; Sessa, WC; Stern, DF | 1 |
| Rodríguez-Fernández, JL; Rozengurt, E | 1 |
| Darnell, JE; Haspel, RL; Salditt-Georgieff, M | 1 |
| Bianchi, R; Eichberg, J; Iyer, S; Rowe-Rendleman, CL | 1 |
| Austin, CD; Shields, D | 1 |
| Calcerrada, MC; Catalán, RE; Gargiulo, L; Liras, A; Martínez, AM | 1 |
| Husøy, T; Mikalsen, SO; Sanner, T; Vikhamar, G | 1 |
| Dhaunsi, GS; Hassid, A; Kaur, K; Matthews, C | 1 |
| Alpern, RJ; Moe, OW; Tsuganezawa, H; Yamaji, Y | 1 |
| DeFranco, DB; Liu, J; Yang, J | 1 |
| Aoyama, H; Ferreira, CV; Granjeiro, JM; Jucá, MB; Taga, EM | 1 |
| He, J; Oleinick, NL; Xue, LY | 1 |
| Bannerman, DD; Goldblum, SE | 1 |
| Belisario, MA; Di Martino, E; Di Natale, P; Esposito, S; Garbi, C; Nitsch, L; Squillacioti, C; Staiano, N | 1 |
| Fendrick, JL; Geary, SM; Konishi, I; O'Brien, TJ; Parmley, TH; Quirk, JG | 1 |
| Hershkoviz, R; Kachalsky, SG; Lider, O; Miron, S | 1 |
| Sasaki, T; Schaller, MD | 1 |
| Berg, LJ; Bunnell, SC; Heyeck, SD; Wilcox, HM | 1 |
| Baker, RD; Baker, SS; Gupta, A; Holycross, M; Rao, RK | 1 |
| Benfenati, F; Leoni, C; Menegon, A; Valtorta, F | 1 |
| Durden, DL; Erdreich-Epstein, A; Liu, M; Liu, Y | 1 |
| Aoyama, H; Ferreira, CV; Granjeiro, JM; Taga, EM | 1 |
| Briski, KP; Hosick, HL; McIntyre, BS; Sylvester, PW | 1 |
| Balabanova, L; Leffler, CW; Parfenova, H | 1 |
| Cao, ZX; Durham, T; Ganguli, S; McCoy, L; Poehlein, S; Reuland, DJ; Rosenhein, L; Turner, J | 1 |
| Bilton, RF; Hulley, CE; Lowe, GM; Rhodes, ES; Young, AJ | 1 |
| Djiane, J; Edwards, GM; Hennighausen, L; Liu, X; Streuli, CH; Wilford, FH | 1 |
| Carr, BI; Ni, R; Nishikawa, Y | 1 |
| Becker, LE; Erclik, T; Man, HY; Wang, YT | 1 |
| Chambaz, EM; Chinn, A; Feige, JJ; Gaillard, I; Vilgrain, I | 1 |
| Davis-Amaral, EM; Goldstein, L; Leibowitz, KL; Musch, MW | 1 |
| Edwards, SW; Watson, F | 1 |
| Carvalho, CR; Costa, FF; Saad, MJ; Saad, ST; Terra, HT; Vicentin, DL | 1 |
| Collares-Buzato, CB; Hirst, BH; Jepson, MA; Simmons, NL | 1 |
| Blake, DJ; Davies, KE; Loh, NY; Nawrotzki, R; Ruegg, MA | 1 |
| Ando, K; Goto, H; Habu, S; Hozumi, K; Kametani, Y; Kobori, A; Nishimura, T; Saito, T; Sato, T; Yamamoto, T | 1 |
| Grdisa, M | 1 |
| Baeuerle, PA; Béraud, C; Henzel, WJ | 1 |
| Celli, J; Finlay, BB; Goosney, DL; Kenny, B | 1 |
| Grgurevich, S; McVicar, DW; Mikhael, A | 1 |
| Avraham, S; Cheng, K; Kharbanda, S; Kumar, V; Majumder, PK; Nakazawa, A; Pandey, P; Place, A; Saxena, S | 1 |
| Brennan, H; Smith, S; Stoker, A | 1 |
| Haydar, SA; Kuphal, R; Lightfoot, JD; Salant, DJ; Topham, PS | 1 |
| Sagi-Eisenberg, R; Seger, R; Shefler, I | 1 |
| Bird, IN; Bradfield, PF; Buckley, CD; Douglas, MR; Freeman, S; Lord, JM; Pumphrey, NJ; Salmon, M; Taylor, V; Wakelam, MJ; Young, SP | 1 |
| Csortos, C; Garcia, JG; Natarajan, V; Patterson, CE; Schaphorst, K; Siddiqui, R; Verin, AD | 1 |
| Bedoya, FJ; Camacho, MJ; Carballo, M; Conde, J; Conde, M; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Sobrino, F | 1 |
| Holly, JM; Mihai, R; Stewart, CE | 1 |
| Busch, AK; Hansen, LL; Ikeda, Y; Mosthaf, L; Olsen, GS | 1 |
| Brindley, DN; Cui, Y; English, D; Garcia, JG; Natarajan, V; Patterson, C; Siddiqui, R | 1 |
| Ahmad, A; Gorra, VA; Heffernan, CC; Weeks, BS; White, LE; Wilson, PJ | 1 |
| Béguin, P; Carranza, ML; Caverzasio, J; Favre, H; Féraille, E; Geering, K; Gonin, S; Martin, PY; Pedemonte, C; Rousselot, M | 1 |
| Cruz, M; Eneroth, P; Sidén, A; Vargas, VI; Yakisich, JS | 1 |
| Fox, AP; Nucifora, PG | 1 |
| Aggarwal, BB; Chintala, SK; Gokslan, Z; Kyritsis, AP; Mohan, PM; Mohanam, S; Rao, JS; Sawaya, R; Steck, P; Uhm, JH; Yung, WK | 1 |
| Alvarez, K; Bell, MW; Ghalayini, AJ | 1 |
| Cuncic, C; Desmarais, S; Detich, N; Gresser, MJ; Ramachandran, C; Tracey, AS | 1 |
| Blanchetot, C; Buist, A; den Hertog, J | 1 |
| Alam, T; Hamawy, MM; Knechtle, SJ; Manthei, ER; Tsuchida, M | 1 |
| Cammarata, G; Cervello, M; Gambino, R; Isola, G; Sanfilippo, R; Scalia, G; Virruso, L | 1 |
| Aussel, C; Breittmayer, JP; Pelassy, C | 1 |
| Sui, X; Xu, F; Xu, M; Zhao, R; Zhao, ZJ | 1 |
| Cruz, A; DeFouw, DO; DeFouw, LM | 1 |
| Alcón, S; Camello, PJ; García, LJ; Pozo, MJ | 1 |
| Bershadsky, AD; Elbaum, M; Gazit, A; Geiger, B; Levitzki, A; Volberg, T | 1 |
| Araki, Y; Sendo, F; Yu, Y | 1 |
| Asai, DJ; Faruki, S; Geahlen, RL | 1 |
| Barrio, DA; Cortizo, AM; Etcheverry, SB; Ferrer, EG; Sálice, VC; Williams, PA | 1 |
| Dawson, G; Kilkus, J; Schieven, GL | 1 |
| Boland, R; Buitrago, C; De Boland, AR; Morelli, S; Vazquez, G | 1 |
| Eriksson, JW; Yu, ZW | 1 |
| Blaikie, P; Dans, M; Gagnoux-Palacios, L; Giancotti, FG; Klein, S; Mariotti, A | 1 |
| Alessi, DR; Casamayor, A; Grémeaux, T; Grillo, S; Le Marchand-Brustel, Y; Tanti, JF | 1 |
| Garcia, JG; Natarajan, V; Patterson, CE; Schaphorst, KL; Vepa, S; Verin, AD | 1 |
| Frantz, JD; Lindholm, CK; Shoelson, SE; Welsh, M | 1 |
| Alon, R; Chen, LL; Feigelson, SW; Grabovsky, V; Lobb, R; Pepinsky, RB; Winter, E; Yablonski, D; Yednock, T | 1 |
| D'Adamo, MC; Imbrici, P; Pessia, M; Tucker, SJ | 1 |
| Abraham, RT; Busuttil, V; Imbert, V; Livolsi, A; Peyron, JF | 1 |
| Kulms, D; Schwarz, T | 1 |
| Herrera, R; Petruzzelli, L; Takami, M | 1 |
| Arman, M; Gimferrer, I; Lozano, F; Padilla, O; Places, L; Simarro, M; Vilà, JM; Vives, J | 1 |
| James, SR; Löthgren, A; McCartney, M; Rupp Thuresson, E | 1 |
| Abrahamsen, H; Horejsí, V; Mustelin, T; Rolstad, B; Schraven, B; Taskén, K; Torgersen, KM; Vang, T; Yaqub, S | 1 |
| Elis, W; Gimborn, K; Huber, M; Leitges, M | 1 |
| Hill, MA; Murphy, TV; Spurrell, BE | 1 |
| Bhat, GJ; Gunaje, JJ | 1 |
| Barisone, I; Di Mauro, D; Fumagalli, G; Sala, C; Sava, A | 1 |
| Boulven, I; Desmyter, C; Harbon, S; Leiber, D; Robin, P | 1 |
| Ekman, S; Engström, U; Heldin, CH; Kallin, A; Rönnstrand, L | 1 |
| Kikawa, KD; Kinch, MS; Van Etten, RL; Vidale, DR | 1 |
| Baker, KM; Booz, GW; Day, JN | 1 |
| Angelini, DJ; Cross, AS; Goldblum, SE; Hasday, JD; Hyun, SW; Kiser, TD; Passaniti, A; Romer, LH; Sakarya, S; Schaphorst, KL; Sui, X; Wang, P; Young, BA | 1 |
| Abella, A; Camps, M; Carpéné, C; Claret, M; Fernández-Alvarez, J; Gomis, R; Gumà, A; Marti, L; Palacín, M; Testar, X; Viguerie, N; Zorzano, A | 1 |
| Horwitz, J; Kobayashi, MS; Maglio, J; Mehta, S; Sipple, AM | 1 |
| Biagioni, C; Catarzi, S; Favilli, F; Giannoni, E; Iantomasi, T; Vincenzini, MT | 1 |
| Andersen, HS; Guo, XL; Iversen, LF; Kastrup, JS; Mortensen, SB; Møller, KB; Møller, NP; Pedersen, AK; Peters, GH; Zhang, ZY | 1 |
| Alvarez, SE; Ciuffo, GM; Fuentes, LB | 1 |
| Ericson, SG; Yao, Y; Zhou, Q | 1 |
| Fukaya, Y; Yamaguchi, M | 1 |
| Radha, V; Rajanna, A; Swarup, G | 1 |
| Allebach, J; Brown, P; Chen, P; Kim, KT; Levis, M; Small, D | 1 |
| Chan, FH; Hegde, RS; Kattamuri, C; Rayapureddi, JP | 1 |
| Cand, F; Christé, G; Gulino-Debrac, D; Huber, P; Lambeng, N; Rampon, C; Vilgrain, I; Wallez, Y | 1 |
| Begum, S; Cope, AP; Peirce, MJ; Saklatvala, J; Wait, R | 1 |
| Bastiaens, PI; Hasenberg, T; Herzog, T; Keese, M; Magdeburg, RJ; Offterdinger, M; Pepperkok, R; Sturm, JW | 1 |
| Anderton, BH; Bird, IN; Brion, JP; Byers, HL; Derkinderen, P; Hanger, DP; Kellie, S; Lenz, C; Leroy, K; Leung, KY; Noble, W; Perera, T; Price, C; Reynolds, CH; Scales, TM; Van Etten, RA; Ward, MA; Williamson, R | 1 |
| Braunstein, I; Chemnitz, JM; Lanfranco, AR; Riley, JL | 1 |
| Brautigan, DL; Kruszewski, A; Wang, H | 1 |
| Milward, AD; Naseem, KM; Oberprieler, NG; Patel, B; Riba, R | 1 |
| Hamazaki, T; Kehoe, SM; Nakano, T; Terada, N | 1 |
| Adachi, Y; Basuki, W; Hattori, M; Hiromura, M; Sakurai, H; Tayama, K | 1 |
| Mehdi, MZ; Pandey, SK; Srivastava, AK; Vardatsikos, G | 1 |
| Babnigg, G; Lee, KM; Son, SW; Villereal, ML | 1 |
| Crockett, DK; Elenitoba-Johnson, KS; Lim, MS; Schumacher, JA | 1 |
| Boeri Erba, E; Bunkenborg, J; Cabodi, S; Defilippi, P; Di Stefano, P; Jensen, ON; Matthiesen, R; Schulze, WX; Tarone, G | 1 |
| Abdullah, LH; Davis, CW | 1 |
| Dráber, P; Dráberová, L; Farghali, H; Heneberg, P; Smíd, F | 1 |
| Albigès-Rizo, C; Badowski, C; Block, MR; Chabadel, A; Grichine, A; Jurdic, P; Oddou, C; Pawlak, G; Pfaff, M | 1 |
| Lau, CP; Li, GR; Tse, HF; Wang, Y; Zhang, DY | 1 |
| Blouin, R; Daviau, A; Di Fruscio, M | 1 |
| Bailey, JL; Leclerc, P; Pons-Rejraji, H | 2 |
| Brown, C; Buettner, R; Hedvat, M; Jensen, M; Jove, R; Schroeder, A; Scuto, A; Starr, R; Yang, F | 1 |
| Chen, SL; Cheng, CH; Du, JY; Huang, JH; Li, S; Ruan, YC; Zhang, G; Zhou, WL; Zuo, WL | 1 |
| Gupta, V; Kalayarasan, S; Mitra, A; Radha, V | 1 |
| Ferns, MJ; Rudell, JB | 1 |
| Broadbent, JR; Cefalo, AD; Welker, DL | 1 |
| Augustine, MM; Broadwater, M; Chen, J; Chen, L; Flies, SJ; Han, X; Iliopoulou, BP; Luo, L; Phennicie, RT; Ruff, W; Taube, JM; Xu, H; Yao, S; Zheng, L; Zhu, G; Zhu, Y | 1 |
| Deng, XL; Li, GR; Liu, YG; She, G; Song, Z; Sun, HY; Wang, Y; Xiao, GS | 1 |
| Babichev, Y; Dong, G; Gelkop, S; Isakov, N; Kalifa, R; Nath, PR | 1 |
| Aballo, T; Chua, XY; Edmondson, RD; Mackintosh, SG; Mensah, T; Salomon, AR | 1 |
| Leonard, D; Mazhar, S; Narla, G; Schlatzer, D; Sosa, A; Thomas, D | 1 |
| Anrather, D; Ellmeier, W; Frohner, IE; Hartl, M; Mudrak, I; Ogris, E; Preglej, T; Schüchner, S; Sontag, E; Sontag, JM; Wadzinski, BE | 1 |
236 other study(ies) available for phosphotyrosine and vanadates
| Article | Year |
|---|---|
Inhibition of tyrosine phosphorylation potentiates substrate-induced neurite growth.
Topics: Animals; Brain; Catechols; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Chick Embryo; Culture Media; Extracellular Matrix Proteins; Genistein; Isoflavones; Nerve Tissue Proteins; Neurites; Neurons; Nitriles; Phenols; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; Tyrosine; Tyrphostins; Vanadates | 1992 |
Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation.
Topics: Animals; Calcium; Cell Line; Cells, Cultured; Cytosol; Flow Cytometry; Gene Expression Regulation; Humans; Hydrogen Peroxide; Immunoblotting; Kinetics; Lymphocyte Activation; Mice; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Interleukin-2; RNA; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1992 |
The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Humans; Immunoblotting; Ligands; Mice; Mice, Inbred BALB C; Oncogene Protein pp60(v-src); Oncogene Protein v-crk; Oncogene Proteins; Phosphotyrosine; Rats; Retroviridae Proteins, Oncogenic; Sulfhydryl Compounds; Tyrosine; Vanadates | 1992 |
Zymosan-triggered tyrosine phosphorylation in mouse bone-marrow-derived macrophages is enhanced by respiratory-burst priming agents.
Topics: Animals; Benzoquinones; Bone Marrow Cells; Cells, Cultured; Cinnamates; Enzyme Activation; In Vitro Techniques; Interferon-gamma; Lactams, Macrocyclic; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred CBA; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Respiratory Burst; Rifabutin; Sulfides; Tumor Necrosis Factor-alpha; Tyrosine; Vanadates; Zymosan | 1992 |
The insulinomimetic agents H2O2 and vanadate stimulate tyrosine phosphorylation of potential target proteins for the insulin receptor kinase in intact cells.
Topics: Animals; CHO Cells; Cricetinae; Hydrogen Peroxide; In Vitro Techniques; Insulin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Transfection; Tyrosine; Vanadates | 1992 |
Nerve growth factor mediates signal transduction through trk homodimer receptors.
Topics: 3T3 Cells; Animals; Cell Line; Cysteine; Humans; Kinetics; Macromolecular Substances; Methionine; Mice; Nerve Growth Factors; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Proteins; Signal Transduction; Transfection; Tyrosine; Vanadates | 1992 |
Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages.
Topics: Animals; Bone Marrow Cells; Gene Expression; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Respiratory Burst; RNA, Messenger; src-Family Kinases; Tyrosine; Vanadates | 1992 |
Insulin and orthovanadate stimulate multiple phosphotyrosine-containing serine kinases.
Topics: Amino Acid Sequence; Animals; Cytosol; DNA; Enzyme Activation; Fibroblasts; Humans; Insulin; Isoenzymes; Mice; Molecular Sequence Data; Molecular Weight; Oligopeptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Insulin; Recombinant Proteins; Stimulation, Chemical; Tyrosine; Vanadates | 1992 |
Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Sulfuric Acid Esters; Tyrosine; Vanadates | 1992 |
Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3'-kinase upon its association with pp185 (IRS-1) in intact rat livers.
Topics: Animals; Blotting, Western; Enzyme Activation; Hydrogen Peroxide; Insulin; Insulin Receptor Substrate Proteins; Liver; Macromolecular Substances; Male; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine; Vanadates | 1992 |
Kinase inhibition by a phosphorylated peptide corresponding to the major insulin receptor autophosphorylation domain.
Topics: Amino Acid Sequence; Binding, Competitive; Immunosorbent Techniques; Molecular Sequence Data; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein-Tyrosine Kinases; Receptor, Insulin; Tyrosine; Vanadates | 1992 |
Okadaic acid and vanadate inhibit collagen-induced platelet aggregation; the functional relation of phosphatases on platelet aggregation.
Topics: Adenosine Triphosphate; Blood Platelets; Collagen; Depression, Chemical; Ethers, Cyclic; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Phosphatase 1; Serotonin; Tyrosine; Vanadates | 1992 |
Vanadate stimulates oxygen consumption and tyrosine phosphorylation in electropermeabilized human neutrophils.
Topics: Adenosine Triphosphate; Cell Membrane Permeability; Electricity; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Magnesium; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1990 |
Phosphotyrosine-containing lactate dehydrogenase is restricted to the nuclei of PC12 pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Line; Cell Nucleus; Chromatography, Affinity; Cytoplasm; DNA-Binding Proteins; Isoenzymes; L-Lactate Dehydrogenase; Pheochromocytoma; Phosphates; Phosphorus Radioisotopes; Phosphotyrosine; Rats; Tyrosine; Vanadates | 1990 |
Serum independence of transcription from the promoter of an avian retrovirus in v-src-transformed cells is a primary, intracellular effect of increased tyrosine phosphorylation.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Kinetics; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Phosphotyrosine; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Temperature; Transfection; Tyrosine; Vanadates | 1990 |
Activation of permeabilized HL60 cells by vanadate. Evidence for divergent signalling pathways.
Topics: Actins; Adenosine Triphosphate; Amanitins; Calcium; Cell Membrane Permeability; Exocytosis; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Immunoblotting; Leukemia, Promyelocytic, Acute; Muramidase; NADP; Neutrophils; Oxygen Consumption; Phosphotyrosine; Polymers; Signal Transduction; Thionucleotides; Tumor Cells, Cultured; Tyrosine; Vanadates | 1990 |
Inverse correlation between tyrosine phosphorylation and collagenase production in chondrocytes.
Topics: Animals; Blood; Cartilage, Articular; Cattle; Cell Division; Goats; Microbial Collagenase; Phosphorylation; Phosphotyrosine; Proteoglycans; Rats; Tyrosine; Vanadates | 1990 |
A low-molecular weight acid phosphatase present in crystalline preparations of rabbit skeletal muscle glycogen phosphorylase b.
Topics: Acid Phosphatase; Animals; Chromatography, Gel; Hydrogen-Ion Concentration; Hydrolysis; Molecular Weight; Muscles; Nitrophenols; Organophosphorus Compounds; Phosphorylase b; Phosphotyrosine; Rabbits; Substrate Specificity; Tyrosine; Vanadates; Zinc | 1990 |
Activation of a membrane-associated phosphatidylinositol kinase through tyrosine-protein phosphorylation by naphthoquinones and orthovanadate.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Cell Membrane; Chromatography, Affinity; Kinetics; Liver; Male; Naphthoquinones; Phosphorylation; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Tyrosine; Vanadates | 1990 |
Cyclin B targets p34cdc2 for tyrosine phosphorylation.
Topics: Animals; Aphidicolin; CDC2 Protein Kinase; Cell Cycle; Cyclins; Diterpenes; Emetine; Fertilization; Mitosis; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Sea Urchins; Time Factors; Tyrosine; Vanadates | 1991 |
Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.
Topics: Age Factors; Animals; Cell Adhesion; Cell Communication; Cell Membrane; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique; Genes, src; Liver; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); Rats; src-Family Kinases; Tyrosine; Vanadates | 1991 |
Distinct patterns of tyrosine phosphorylation during the life cycle of Trypanosoma brucei.
Topics: Animals; Blotting, Western; Chromatography, Ion Exchange; Eflornithine; Electrophoresis, Polyacrylamide Gel; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Trypanosoma brucei brucei; Tyrosine; Vanadates | 1991 |
Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites.
Topics: Granulocytes; Humans; Leukemia, Prolymphocytic; NADP; Oxygen Consumption; Phosphorylation; Phosphotyrosine; Superoxides; Tumor Cells, Cultured; Tyrosine; Vanadates; Vanadium | 1991 |
Myeloid differentiation associated tyrosine protein kinase activity in WEHI-3B murine monomyelocytic leukemia cells.
Topics: Animals; Cell Differentiation; Cell Division; Flow Cytometry; Immunoblotting; Kinetics; Leukemia, Myelomonocytic, Acute; Mice; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1991 |
Stimulation of tyrosine kinase activity in anti-phosphotyrosine immune complexes of Swiss 3T3 cell lysates occurs rapidly after addition of bombesin, vasopressin, and endothelin to intact cells.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antigen-Antibody Complex; Bombesin; Calcimycin; Cell-Free System; Endothelins; Gastrins; Kinetics; Mice; Molecular Sequence Data; Molecular Weight; Neuropeptides; Peptides; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Substrate Specificity; Tyrosine; Vanadates; Vasopressins | 1991 |
Prostatic epithelial cells in culture: phosphorylation of protein tyrosyl residues and tyrosine protein kinase activity.
Topics: Animals; Cells, Cultured; Dogs; Epithelial Cells; Epithelium; Growth Substances; Magnesium; Male; Manganese; Molecular Weight; Phosphorylation; Phosphotyrosine; Prostate; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Steroids; Subcellular Fractions; Tyrosine; Vanadates | 1991 |
Demonstration of separate phosphotyrosyl- and phosphoseryl- histone phosphatase activities in the plasma membranes of a human astrocytoma.
Topics: 4-Nitrophenylphosphatase; Astrocytoma; Cell Line; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Diphosphates; Histones; Humans; Hydrolysis; In Vitro Techniques; Nitrophenols; Nucleotides; Organophosphorus Compounds; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Tissue Distribution; Tyrosine; Vanadates; Vanadium | 1985 |
Transformation of cells by an inhibitor of phosphatases acting on phosphotyrosine in proteins.
Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Deoxyglucose; Kinetics; Mice; Moloney murine sarcoma virus; Phosphatidylinositols; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphotyrosine; Rats; Tyrosine; Vanadates; Vanadium; Zinc | 1985 |
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation.
Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Cell Transformation, Viral; Enzyme Activation; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins pp60(c-src); Rats; Tyrosine; Vanadates; Vanadium; Viral Proteins | 1985 |
Characterization of the phosphotyrosyl protein phosphatase activity of calmodulin-dependent protein phosphatase.
Topics: Amino Acid Sequence; Animals; Brain; Calmodulin; Cattle; Fluorides; Kinetics; Manganese; Myocardium; Myosins; Nickel; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Serine; Tyrosine; Vanadates; Vanadium; Zinc | 1986 |
gp140v-fms molecules expressed at the surface of cells transformed by the McDonough strain of feline sarcoma virus are phosphorylated in tyrosine and serine.
Topics: Animals; Cats; Cell Transformation, Neoplastic; Genes; Genes, Viral; Oncogene Protein gp140(v-fms); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Retroviridae; Retroviridae Proteins; Serine; Tyrosine; Vanadates; Vanadium | 1986 |
Vanadate stimulation of phosphotyrosine protein levels in quiescent Nakano mouse lens cells.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Lens, Crystalline; Mice; Mice, Inbred Strains; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Subcellular Fractions; Time Factors; Tyrosine; Vanadates; Vanadium | 1987 |
Analysis of pp60c-src tyrosine kinase activity and phosphotyrosyl phosphatase activity in human colon carcinoma and normal human colon mucosal cells.
Topics: Adenocarcinoma; Buffers; Cells, Cultured; Colonic Neoplasms; Humans; Immunologic Techniques; Intestinal Mucosa; Oncogene Protein pp60(v-src); Peptide Mapping; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine; Vanadates | 1987 |
Vanadate-treated baby hamster kidney fibroblasts show cytoskeleton and adhesion patterns similar to their Rous sarcoma virus-transformed counterparts.
Topics: Actin Cytoskeleton; Animals; Avian Sarcoma Viruses; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Cytoskeleton; Fibroblasts; Kidney; Phenotype; Phosphoproteins; Phosphotyrosine; Tyrosine; Vanadates | 1988 |
Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.
Topics: Adenosine Triphosphate; Adipose Tissue; Arsenicals; Cell Line; Deoxyglucose; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Insulin; Kinetics; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Trypsin; Tyrosine; Vanadates | 1988 |
The insulin-like effect of vanadate on lipolysis in rat adipocytes is not accompanied by an insulin-like effect on tyrosine phosphorylation.
Topics: Adipose Tissue; Animals; Immunoblotting; Insulin; Isoproterenol; Lipolysis; Male; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine; Vanadates | 1989 |
Phosphorylation of the insulin receptor in permeabilized adipocytes is coupled to a rapid dephosphorylation reaction.
Topics: Adipose Tissue; Animals; Cell Membrane; Digitonin; Insulin; Kinetics; Male; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine; Vanadates | 1989 |
Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis.
Topics: Animals; CDC2 Protein Kinase; Cell Cycle; Enzyme Activation; Mice; Mitosis; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protamine Kinase; Structure-Activity Relationship; Time Factors; Tyrosine; Vanadates | 1989 |
Role of protein tyrosine phosphorylation in the NGF response.
Topics: Actin Cytoskeleton; Animals; Carbazoles; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Indole Alkaloids; Insulin; Microscopy, Fluorescence; Microtubules; Nerve Growth Factors; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1989 |
Identification of proteins cross-reactive to phosphotyrosine antibodies and of a tyrosine kinase activity in boar spermatozoa.
Topics: Amino Acid Sequence; Animals; Antibodies; Blotting, Western; Calcimycin; Cross Reactions; Male; Molecular Sequence Data; Octoxynol; Oligopeptides; Phosphorylation; Phosphotyrosine; Polyethylene Glycols; Protein-Tyrosine Kinases; Solubility; Spermatozoa; Swine; Tyrosine; Vanadates | 1989 |
Respiratory burst and tyrosine phosphorylation by vanadate.
Topics: Alkaloids; Animals; Cell Membrane; Cells, Cultured; Enzyme Inhibitors; Female; Guinea Pigs; Membrane Proteins; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Respiratory Burst; Signal Transduction; Staurosporine; Superoxides; Vanadates | 1995 |
Tyrosine kinase-dependent assembly of actin plaques linking Fc epsilon R1 cross-linking to increased cell substrate adhesion in RBL-2H3 tumor mast cells.
Topics: Actins; Animals; Antigens; Cell Adhesion; Mast Cells; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor of protein tyrosine phosphatases.
Topics: Base Sequence; Calcium; Genes, fos; Humans; Interleukin-2; Kinetics; Leukemia; Leukocyte Common Antigens; Lymphocyte Activation; Molecular Sequence Data; NF-kappa B; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Transcription, Genetic; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1994 |
Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols.
Topics: Acetylcysteine; Angiotensin II; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Drug Synergism; Egtazic Acid; Enzyme Activation; Flavonoids; Flavonols; Indomethacin; Liver; Masoprocol; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Rats; Tyrosine; Vanadates | 1994 |
Inhibition of epidermal growth factor-dependent protein tyrosine phosphorylation by phorbol myristate acetate is mediated by protein tyrosine phosphatase activity.
Topics: 3T3 Cells; Animals; Cell Line; Egtazic Acid; Epidermal Growth Factor; ErbB Receptors; Humans; Mice; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sodium Fluoride; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1994 |
Vanadate augments insulin-stimulated insulin receptor kinase activity and prolongs insulin action in rat adipocytes. Evidence for transduction of amplitude of signaling into duration of response.
Topics: Adipocytes; Animals; Dose-Response Relationship, Drug; Half-Life; Insulin; Kinetics; Lipids; Male; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction; Tyrosine; Vanadates | 1994 |
Activation of macrophage PtdIns-PLC by phorbol ester and vanadate: involvement of reactive oxygen species and tyrosine phosphorylation.
Topics: Animals; Enzyme Activation; Female; Macrophages, Peritoneal; Mice; Phorbol Esters; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphorylation; Phosphotyrosine; Reactive Oxygen Species; Tyrosine; Vanadates | 1994 |
Lipocortin 2 (annexin 2) is a major substrate for constitutive tyrosine kinase activity in chondrocytes.
Topics: Animals; Annexin A2; Cartilage, Articular; Cattle; Cells, Cultured; Chromatography, Affinity; Collagenases; Gene Expression; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Substrate Specificity; Tyrosine; Vanadates | 1994 |
Increase of phosphotyrosine levels in mouse urine and liver during liver regeneration after partial hepatectomy.
Topics: Animals; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Mice; Mice, Inbred Strains; Phosphotyrosine; Protein Tyrosine Phosphatases; Reference Values; Time Factors; Tyrosine; Vanadates | 1994 |
Junctional uvomorulin/E-cadherin and phosphotyrosine-modified protein content are correlated with paracellular permeability in Madin-Darby canine kidney (MDCK) epithelia.
Topics: Animals; Cadherins; Cell Line; Cell Membrane; Cell Membrane Permeability; Dogs; Electric Conductivity; Electrophysiology; Epithelium; Hydrogen Peroxide; Intercellular Junctions; Kidney; Membrane Potentials; Microscopy, Electron; Microscopy, Electron, Scanning; Phosphoproteins; Phosphotyrosine; Tyrosine; Vanadates | 1994 |
Vanadate stimulates differentiation and neurite outgrowth in rat pheochromocytoma PC12 cells and neurite extension in human neuroblastoma SH-SY5Y cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Differentiation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Humans; Immunoblotting; Kinetics; Molecular Weight; Nerve Growth Factors; Neurites; Neuroblastoma; Neurons; PC12 Cells; Pheochromocytoma; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Does the insulin-mimetic action of vanadate involve insulin receptor kinase?
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Kinetics; Liver; Male; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Reference Values; Tyrosine; Vanadates; Weight Gain | 1993 |
Stimulatory effect of pervanadate on calcium signals and histamine secretion of RBL-2H3 cells.
Topics: Animals; Calcium; Catalase; Histamine Release; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Leukemia, Basophilic, Acute; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
UV radiation induces DNA fragmentation and cell death in B16 melanoma sensitized by bromodeoxyuridine: impaired c-jun induction and defective tyrosine phosphorylation signalling.
Topics: Animals; Bromodeoxyuridine; Cell Death; Cell Survival; DNA Damage; DNA, Neoplasm; Ethers, Cyclic; Genes, jun; Immunoblotting; Melanoma, Experimental; Mice; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-jun; Radiation-Sensitizing Agents; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Ultraviolet Rays; Vanadates | 1994 |
Transforming growth factor beta down-regulates Src family protein tyrosine kinase signaling pathways.
Topics: Blotting, Western; Cell Line; Humans; Male; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphoproteins; Phosphotyrosine; Prostatic Neoplasms; Protein-Tyrosine Kinases; Receptors, Transforming Growth Factor beta; Signal Transduction; src-Family Kinases; Transforming Growth Factor beta; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Regulation of vascular and gastric smooth muscle contractility by pervanadate.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Calcium; Epidermal Growth Factor; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sodium; Stomach; Tyrosine; Vanadates | 1994 |
Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line.
Topics: alpha Catenin; Benzoquinones; beta Catenin; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion; Cell Aggregation; Cell Line; Culture Techniques; Cytoskeletal Proteins; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Fibroblasts; Fluorescent Antibody Technique; Gels; Humans; Lactams, Macrocyclic; Neoplasm Invasiveness; Neoplasm Proteins; Phenotype; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Quinones; Rifabutin; Signal Transduction; Trans-Activators; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine; Vanadates | 1995 |
Tyrosine phosphorylation pathway is involved in interferon-gamma (IFN-gamma) production; effect of sodium ortho vanadate.
Topics: Cell Division; HLA-DR Antigens; Humans; In Vitro Techniques; Interferon-gamma; Leukocytes, Mononuclear; Lymphocyte Activation; Phosphoproteins; Phosphotyrosine; Receptors, Interleukin-2; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Effects of chromium on basal and insulin-induced tyrosine phosphorylation in H4 hepatoma cells: comparison with phorbol-12-myristate-13-acetate and sodium orthovanadate.
Topics: Animals; Chromium; Insulin; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Alpha 1 B, but not alpha 1A, adrenoreceptor activates calcium influx through the stimulation of a tyrosine kinase/phosphotyrosine phosphatase pathway, following noradrenaline-induced emptying of IP3 sensitive calcium stores, in PC Cl3 rat thyroid cell lin
Topics: Animals; Calcium; Cells, Cultured; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Norepinephrine; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Adrenergic, alpha; Signal Transduction; Thyroid Gland; Tyrosine; Vanadates | 1995 |
Functional link between phosphorylation state of membrane proteins and morphological changes of human erythrocytes.
Topics: Anion Exchange Protein 1, Erythrocyte; Erythrocyte Membrane; Ethers, Cyclic; Humans; Membrane Proteins; Microscopy, Electron, Scanning; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Spectrin; Tyrosine; Vanadates | 1995 |
Inhibitory effect of tyrphostin on the replication of herpes simplex virus type 1.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Viral; Chlorocebus aethiops; DNA Replication; Herpesvirus 1, Human; Humans; Nitriles; Phenols; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Tyrosine; Tyrphostins; Vanadates; Vero Cells; Viral Proteins; Virus Replication | 1995 |
Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system.
Topics: Adenosine Triphosphate; Antibodies; Base Sequence; Carcinoma, Squamous Cell; Cell Line; Cell-Free System; Cytosol; Humans; Interferon-gamma; Kinetics; Leukemia, Myeloid; Ligands; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Repetitive Sequences, Nucleic Acid; Skin Neoplasms; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Evidence for a signaling role for the alpha chains of granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors: divergent signaling pathways between GM-CSF/IL-3 and IL-5.
Topics: Alkaloids; Cell Division; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Interleukin-3; Interleukin-5; Kinetics; Leukemia, Erythroblastic, Acute; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
The mitogen-activated protein kinase cascade in rat islets of Langerhans.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Ethers, Cyclic; Glucose; Islets of Langerhans; Isoenzymes; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
RK-682, a potent inhibitor of tyrosine phosphatase, arrested the mammalian cell cycle progression at G1phase.
Topics: Aniline Compounds; Antifungal Agents; Blotting, Western; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Dual Specificity Phosphatase 3; Enzyme Inhibitors; Ethers, Cyclic; G1 Phase; Humans; Kinetics; Leukemia, B-Cell; Okadaic Acid; Organophosphorus Compounds; Phosphoprotein Phosphatases; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyrans; Spiro Compounds; Streptomyces; Tumor Cells, Cultured; Vanadates | 1995 |
Adhesion-inducible DNA synthesis regulated by tyrosine phosphorylation/dephosphorylation.
Topics: Animals; Benzoquinones; Cell Adhesion; Cell Line; DNA; Enzyme Inhibitors; Epithelium; Fibronectins; Lactams, Macrocyclic; Liver; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Signal Transduction; Tyrosine; Vanadates | 1995 |
Exogenous phosphotyrosine modulates epidermal growth factor receptor tyrosine phosphorylation.
Topics: Breast Neoplasms; Cell Division; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1993 |
Effect of orthovanadate on tyrosine phosphorylation of P120 GTPase-activating protein in rat liver macrophages (Kupffer cells).
Topics: Animals; Cells, Cultured; GTPase-Activating Proteins; Kinetics; Kupffer Cells; Phosphorylation; Phosphotyrosine; Proteins; Rats; Subcellular Fractions; Tyrosine; Vanadates | 1993 |
Interleukin 2 regulates Raf-1 kinase activity through a tyrosine phosphorylation-dependent mechanism in a T-cell line.
Topics: Animals; Cell Line; Ethers, Cyclic; Interleukin-2; Kinetics; Mice; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; T-Lymphocytes, Cytotoxic; Tyrosine; Vanadates | 1993 |
Orthovanadate induces translocation of phospholipase C-gamma 1 and -gamma 2 in permeabilized mast cells.
Topics: Animals; Cell Compartmentation; Cell Membrane Permeability; Enzyme Activation; In Vitro Techniques; Isoenzymes; Mast Cells; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Receptor Aggregation; Receptors, IgE; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1993 |
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Blotting, Western; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cytoskeletal Proteins; In Vitro Techniques; Molecular Sequence Data; Oligopeptides; Oncogene Protein v-crk; Oncogenes; Paxillin; Phosphoproteins; Phosphotyrosine; Protein Binding; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Tyrosine; Vanadates | 1993 |
Vanadate-induced contraction of smooth muscle and enhanced protein tyrosine phosphorylation.
Topics: Animals; Calcium; Genistein; Guinea Pigs; Intestine, Large; Isoflavones; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myosins; Peptides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1993 |
Identification and pKa determination of the histidine residues of human low-molecular-weight phosphotyrosyl protein phosphatases: a convenient approach using an MLEV-17 spectral editing scheme.
Topics: Amino Acid Sequence; Base Sequence; Histidine; Humans; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphotyrosine; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Recombinant Proteins; Tyrosine; Vanadates | 1993 |
Cross-talk between adenylate cyclase activation and tyrosine phosphorylation leads to modulation of the actin cytoskeleton and to acute progesterone secretion in ovarian granulosa cells.
Topics: Actins; Adenylyl Cyclases; Animals; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cytoskeleton; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydrogen Peroxide; Microscopy, Electron; Phosphorylation; Phosphotyrosine; Progesterone; Rats; Tyrosine; Vanadates | 1993 |
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.
Topics: Benzoquinones; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Genistein; Humans; Hypotonic Solutions; Intestines; Iodides; Isoflavones; Kinetics; Lactams, Macrocyclic; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Rubidium; Tyrosine; Vanadates; Water-Electrolyte Balance | 1993 |
Tyrosine phosphorylation of a mitogen-activated protein kinase-like protein occurs at a late step in exocytosis. Studies with tyrosine phosphatase inhibitors and various secretagogues in rat RBL-2H3 cells.
Topics: Actins; Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Electrophoresis, Polyacrylamide Gel; Exocytosis; Hexosaminidases; Hydrogen Peroxide; Inositol Phosphates; Kinetics; Leukemia, Basophilic, Acute; Phospholipids; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Tumor Cells, Cultured; Tyrosine; Vanadates | 1993 |
Dephosphorylation on tyrosine of epidermal growth factor receptor is inhibited by Ca2+ pretreatment in isolated liver membrane.
Topics: Adenosine Triphosphate; Animals; Cadaverine; Calcium; Cell Membrane; ErbB Receptors; Immunoblotting; Kinetics; Liver; Phosphorylation; Phosphotyrosine; Tyrosine; Vanadates | 1993 |
Reactive oxygen species mediate phorbol ester-regulated tyrosine phosphorylation and phospholipase A2 activation: potentiation by vanadate.
Topics: Animals; Drug Synergism; Enzyme Activation; Female; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Phospholipases A; Phospholipases A2; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1993 |
Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Collagen; Enzyme Inhibitors; Ethers, Cyclic; Fetus; Fibroblasts; Gene Expression; Genistein; Humans; Isoflavones; Isoquinolines; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphotyrosine; Piperazines; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Skin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vanadates | 1995 |
Protein tyrosine phosphorylation induced by epidermal growth factor and insulin-like growth factor-I in a rat clonal dental pulp-cell line.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Dental Pulp; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Isoflavones; Mice; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor, IGF Type 1; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Thyroid stimulating hormone and N6-2'-O-dibutyryladenosine 3'-5'-cyclic monophosphate decrease 110,000-130,000 M(r) tyrosine-phosphorylated substrate in rat thyroid cells.
Topics: Animals; Antibodies, Monoclonal; Bucladesine; Cell Culture Techniques; Cell Line; Immunoblotting; Insulin-Like Growth Factor I; Molecular Weight; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Vanadates | 1995 |
Arrest at the G2/M transition of the cell cycle by protein-tyrosine phosphatase inhibition: studies on a neuronal and a glial cell line.
Topics: CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Survival; DNA Damage; G2 Phase; Glioma; Histones; Mitosis; Neuroblastoma; Neuroglia; Neurons; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Proteins; RNA; Tumor Cells, Cultured; Vanadates; Vimentin | 1995 |
Protein tyrosine kinases and phosphatases control apoptosis induced by extracellular adenosine 5'-triphosphate.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Cell Line; DNA Damage; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Homeostasis; Isoflavones; Leukemia L1210; Mast-Cell Sarcoma; Mice; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Vanadates | 1996 |
Endogenous reactive oxygen intermediates activate tyrosine kinases in human neutrophils.
Topics: Enzyme Activation; Enzyme Precursors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Neutrophils; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Reactive Oxygen Species; src-Family Kinases; Syk Kinase; Vanadates | 1996 |
GTPgammaS-stimulated phospholipase D activation in human neutrophils occurs by protein kinase C-dependent and -independent pathways but not tyrosine kinases.
Topics: Alkaloids; Benzylidene Compounds; Cell Membrane Permeability; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroquinones; In Vitro Techniques; Indoles; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitriles; Phospholipase D; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 1996 |
Evidence for a TSH-controlled ectophosphotyrosine phosphatase in pig thyroid cultured cells.
Topics: Animals; Cell Communication; Cells, Cultured; Chlorides; Enzyme Inhibitors; Hydrogen-Ion Concentration; Iodides; Iodine Radioisotopes; Kinetics; Molybdenum; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Sodium Fluoride; Swine; Tetramisole; Thyroid Gland; Thyrotropin; Vanadates; Zinc Compounds | 1996 |
Characterization and cloning of a 58/53-kDa substrate of the insulin receptor tyrosine kinase.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Chickens; CHO Cells; Cloning, Molecular; Cricetinae; Drosophila; Gene Expression; Genes, src; GTPase-Activating Proteins; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Molecular Weight; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; ras GTPase-Activating Proteins; Receptor, IGF Type 1; Receptor, Insulin; Transfection; Tumor Suppressor Protein p53; Vanadates | 1996 |
Inhibition of p38 mitogen-activated protein kinase by insulin in cultured fetal neurons.
Topics: Activating Transcription Factor 2; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chickens; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Insulin; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphotyrosine; Transcription Factors; Vanadates | 1996 |
Intracluster restriction of Fc receptor gamma-chain tyrosine phosphorylation subverted by a protein-tyrosine phosphatase inhibitor.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Mice; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptors, IgG; Respiratory Burst; Vanadates | 1996 |
erbB family receptor expression and growth regulation in a newly isolated human breast cancer cell line.
Topics: Base Sequence; Blotting, Western; Breast; Breast Neoplasms; Cell Division; Cell Line; DNA Primers; ErbB Receptors; Female; Gene Expression; Genes, erbB-2; Humans; Kinetics; Molecular Sequence Data; Phosphoproteins; Phosphotyrosine; Pleural Effusion; Polymerase Chain Reaction; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor, ErbB-2; Receptor, ErbB-3; RNA, Messenger; Tumor Cells, Cultured; Vanadates | 1996 |
A stable peroxovanadium compound with insulin-like action in human fat cells.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adipose Tissue; Biological Transport; Biopsy; Carbon Radioisotopes; Female; Glucose; Humans; Hypoglycemic Agents; Insulin; Isoproterenol; Kinetics; Lipolysis; Phosphotyrosine; Placenta; Pregnancy; Receptor, Insulin; Recombinant Proteins; Reference Values; Skin; Vanadates | 1996 |
Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Line; Cell Nucleus; Cloning, Molecular; Cytoplasm; Epidermal Growth Factor; ErbB Receptors; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Male; Membrane Transport Proteins; Mice; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Structure, Secondary; RNA, Messenger; src Homology Domains; Testis; Type C Phospholipases; Vanadates; Zinc Fingers | 1996 |
Phosphotyrosyl protein phosphatase-like activity of a clonal osteoblastic cell line (MC3T3-E1 cell).
Topics: 3T3 Cells; Animals; Cell Line; Clone Cells; Cyclic AMP; Enzyme Inhibitors; Ethers, Cyclic; Histones; Hydrogen-Ion Concentration; Hydrolysis; Mice; Muramidase; Okadaic Acid; Osteoblasts; Peptides; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Vanadates; Zinc | 1995 |
Possible involvement of a tyrosine kinase-dependent pathway in the regulation of phosphoinositide metabolism by vanadate in normal mouse islets.
Topics: Acetylcholine; Androstadienes; Animals; Arginine Vasopressin; Calcium; Cattle; Enzyme Inhibitors; Female; GTP-Binding Proteins; Islets of Langerhans; Mice; Mice, Inbred Strains; Phosphatidylinositols; Phosphodiesterase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Stimulation, Chemical; Tungsten Compounds; Type C Phospholipases; Vanadates; Wortmannin | 1996 |
Tyrosine phosphorylation in inflammatory neutrophils.
Topics: Arthritis, Rheumatoid; Blotting, Western; Enzyme Inhibitors; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidoreductases; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Reference Values; Substance P; Synovial Fluid; Tyrosine; Vanadates | 1996 |
Differential utilization of Trk autophosphorylation sites.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Animals; Humans; Immunologic Techniques; Molecular Sequence Data; Nerve Growth Factors; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Protein Binding; Proteins; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptor, trkA; Receptor, trkC; Receptors, Nerve Growth Factor; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Vanadates | 1996 |
Human cancer cells exhibit protein kinase C-dependent c-erbB-2 transmodulation that correlates with phosphatase sensitivity and kinase activity.
Topics: Animals; Cell Line; Humans; Mice; Phorbol 12,13-Dibutyrate; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, ErbB-2; Substrate Specificity; Threonine; Vanadates | 1996 |
Regulation of tyrosine phosphorylation and protein tyrosine phosphatases during oligodendrocyte differentiation.
Topics: Animals; Cell Differentiation; Cytosol; Nerve Tissue Proteins; Oligodendroglia; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Subcellular Fractions; Tyrosine; Vanadates | 1996 |
Effects of mitogens on androgen receptor-mediated transactivation.
Topics: Animals; Cell Line; COS Cells; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; HeLa Cells; Insulin-Like Growth Factor I; Intracellular Membranes; Isoflavones; Ligands; Mitogens; Phosphorylation; Phosphotyrosine; Rats; Receptors, Androgen; Signal Transduction; Transcriptional Activation; Tyrosine; Vanadates | 1996 |
Apoptosis in hematopoietic cells is associated with an extensive decrease in cellular phosphotyrosine content that can be inhibited by the tyrosine phosphatase antagonist pervanadate.
Topics: Animals; Apoptosis; Blood Cells; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flow Cytometry; Hematopoiesis; Humans; In Vitro Techniques; Mice; Phosphotyrosine; Protein Tyrosine Phosphatases; Thymus Gland; Tumor Cells, Cultured; Vanadates | 1996 |
Stimulation of inorganic phosphate transport by insulin-like growth factor I and vanadate in opossum kidney cells is mediated by distinct protein tyrosine phosphorylation processes.
Topics: Adaptor Proteins, Signal Transducing; Animals; Benzoquinones; Cell Line; Enzyme Inhibitors; Epithelium; Genistein; Humans; Insulin; Insulin-Like Growth Factor I; Isoflavones; Kidney; Lactams, Macrocyclic; Naphthalenes; Oncogene Proteins; Opossums; Phosphates; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Recombinant Proteins; Rifabutin; Signal Transduction; Sodium; Staurosporine; Vanadates | 1996 |
Leishmania-induced tyrosine phosphorylation in the host macrophage and its implication to infection.
Topics: Animals; Benzoquinones; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Genistein; Immunohistochemistry; Isoflavones; Lactams, Macrocyclic; Leishmaniasis; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Microscopy, Electron; Nitriles; Organophosphorus Compounds; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Staurosporine; Tyrphostins; Vanadates | 1996 |
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1.
Topics: Animals; Aorta; Cattle; Caveolin 1; Caveolins; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Kinetics; Membrane Proteins; Microcirculation; Nitric Oxide Synthase; Phosphates; Phosphorylation; Phosphotyrosine; Protein Binding; Pulmonary Circulation; Tyrosine; Vanadates | 1996 |
Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Bombesin; Bradykinin; Calcium; Cell Adhesion Molecules; Dimethyl Sulfoxide; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Kinetics; Mice; Molecular Sequence Data; Peptide Fragments; Phorbol Esters; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; src-Family Kinases; Substrate Specificity; Vanadates; Vasopressins | 1996 |
The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.
Topics: Acetylcysteine; Blotting, Western; Cell Nucleus; Cysteine Endopeptidases; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fibroblasts; Humans; Interferon-gamma; Leupeptins; Multienzyme Complexes; Nuclear Proteins; Phosphorylation; Phosphotyrosine; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Receptors, Interferon; Signal Transduction; STAT1 Transcription Factor; Staurosporine; Trans-Activators; Vanadates | 1996 |
Tyrosine phosphorylation of myelin protein PO.
Topics: Animals; Hydrolysis; Male; Myelin P0 Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Vanadates | 1996 |
Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Enzyme Inhibitors; Golgi Apparatus; GTP-Binding Proteins; Humans; Membrane Proteins; Molecular Sequence Data; Nitriles; Phosphorylation; Phosphotyrosine; Pituitary Gland; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Tyrosine; Tyrphostins; Vanadates; Zinc | 1996 |
Protein tyrosine phosphatase activity modulation by endothelin-1 in rabbit platelets.
Topics: Animals; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Endothelin-1; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Vanadates | 1997 |
Induction of phosphotyrosine in the gap junction protein, connexin43.
Topics: Animals; Cells, Cultured; Connexin 43; Cricetinae; Gap Junctions; Mesocricetus; Phosphorylation; Phosphotyrosine; Vanadates | 1997 |
NO increases protein tyrosine phosphatase activity in smooth muscle cells: relationship to antimitogenesis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Aorta, Thoracic; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; Cyclic GMP; DNA; Female; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vanadates | 1997 |
Intracellular acidosis activates c-Src.
Topics: Acidosis; Animals; Cell Line; Cytosol; Enzyme Activation; Kidney Tubules, Proximal; Mice; Phosphotyrosine; Propionates; Proto-Oncogene Proteins pp60(c-src); Vanadates | 1997 |
Subnuclear trafficking of glucocorticoid receptors in vitro: chromatin recycling and nuclear export.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cell Compartmentation; Cell Membrane Permeability; Cell Nucleus; Chromatin; Corticosterone; Digitonin; Enzyme Inhibitors; Genistein; Heparin; HSP90 Heat-Shock Proteins; Isoflavones; Liver; Liver Neoplasms, Experimental; Microcystins; Molybdenum; Peptides, Cyclic; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Glucocorticoid; Tumor Cells, Cultured; Tungsten Compounds; Vanadates | 1997 |
Bovine kidney low molecular weight acid phosphatase: FMN-dependent kinetics.
Topics: Acid Phosphatase; Animals; Cattle; Chloromercuribenzoates; Copper; Electrophoresis, Polyacrylamide Gel; Flavin Mononucleotide; Guanosine; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Kidney; Kinetics; Molecular Weight; Naphthalenes; Nitrophenols; Organophosphates; Organophosphorus Compounds; p-Chloromercuribenzoic Acid; Phosphotyrosine; Pyridoxal Phosphate; Substrate Specificity; Vanadates | 1997 |
Rapid tyrosine phosphorylation of HS1 in the response of mouse lymphoma L5178Y-R cells to photodynamic treatment sensitized by the phthalocyanine Pc 4.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Blood Proteins; Cell Death; Enzyme Inhibitors; Genistein; Indoles; Isoflavones; Leukemia L5178; Light; Mice; Molecular Weight; Phosphorylation; Phosphotyrosine; Photochemotherapy; Photosensitizing Agents; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Vanadates | 1997 |
Endotoxin induces endothelial barrier dysfunction through protein tyrosine phosphorylation.
Topics: Animals; Benzoquinones; Biological Transport; Cattle; Cell Adhesion Molecules; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Endotoxins; Enzyme Inhibitors; Escherichia coli; Genistein; Isoflavones; Lactams, Macrocyclic; Lipopolysaccharides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pulmonary Artery; Quinones; Rifabutin; Serum Albumin, Bovine; Vanadates | 1997 |
Echistatin induces decrease of pp125FAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells.
Topics: Actin Cytoskeleton; Actins; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Membrane; Enzyme Inhibitors; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Intercellular Signaling Peptides and Proteins; Melanoma; Mice; Peptides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Vanadates; Viper Venoms | 1997 |
CA125 phosphorylation is associated with its secretion from the WISH human amnion cell line.
Topics: Amnion; Aprotinin; CA-125 Antigen; Cell Line; Cytoplasm; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Hydrolysis; Immunohistochemistry; Phosphorylation; Phosphotyrosine; Signal Transduction; Vanadates | 1997 |
Pervanadate-induced adhesion of CD4+ T cell to fibronectin is associated with tyrosine phosphorylation of paxillin.
Topics: CD4-Positive T-Lymphocytes; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Fibronectins; Humans; Lymphocyte Activation; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Time Factors; Vanadates | 1997 |
Differential signaling by the focal adhesion kinase and cell adhesion kinase beta.
Topics: Animals; Binding Sites; Cell Adhesion Molecules; Chick Embryo; Crk-Associated Substrate Protein; Cytoskeletal Proteins; DNA Primers; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Glutathione Transferase; Microfilament Proteins; Paxillin; Phosphoproteins; Phosphotyrosine; Polymerase Chain Reaction; Protein Engineering; Protein-Tyrosine Kinases; Proteins; Recombinant Fusion Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; Tensins; Vanadates | 1997 |
Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity.
Topics: Amino Acid Sequence; Animals; Cell Line; Conserved Sequence; Enzyme Activation; Humans; Jurkat Cells; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphotyrosine; Point Mutation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Proteins; Spodoptera; src-Family Kinases; T-Lymphocytes; Transfection; Tyrosine; Vanadates | 1997 |
Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation.
Topics: Arsenicals; Bumetanide; Calcium; Cell Line; Cell Membrane Permeability; Electric Conductivity; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Intestinal Mucosa; Kinetics; Mannitol; Membrane Potentials; Octoxynol; Oxidants; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Tyrosine; Vanadates | 1997 |
Downregulation of MAP kinase activity signalled by HIV-1-gp120 coat protein in granular neurons and glial cells from rat cerebellum.
Topics: Animals; Antibodies; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebellum; Down-Regulation; HIV Envelope Protein gp120; Neuroglia; Neurons; Phosphorylation; Phosphotyrosine; Potassium; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Vanadates | 1997 |
Protein tyrosine phosphatase inhibitors in Fc gamma RI-induced myeloid oxidant signaling.
Topics: Arsenicals; Cell Line; Enzyme Inhibitors; Humans; Leukocytes; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptors, IgG; Respiratory Burst; Signal Transduction; Ubiquitin-Protein Ligases; Vanadates | 1997 |
Soybean seed acid phosphatases: unusual optimum temperature and thermal stability studies.
Topics: Acid Phosphatase; Cytoplasm; Diphosphates; Enzyme Stability; Glycine max; Isoenzymes; Nitrophenols; Octoxynol; Organophosphorus Compounds; Phosphates; Phosphotyrosine; Plant Proteins; Seeds; Temperature; Vanadates | 1998 |
Effects of protein tyrosine phosphatase inhibitors on EGF- and insulin-dependent mammary epithelial cell growth.
Topics: Animals; Cell Division; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Female; Insulin; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Phosphotyrosine; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Vanadates | 1998 |
Posttranslational regulation of cyclooxygenase by tyrosine phosphorylation in cerebral endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Aorta; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Membrane Proteins; Microcirculation; Muscle, Smooth, Vascular; Nitriles; Nitrobenzenes; Phenols; Phosphoproteins; Phosphorylation; Phosphotyrosine; Prostaglandin-Endoperoxide Synthases; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Sulfonamides; Swine; Tyrphostins; Vanadates | 1998 |
The cellular intake kinetics and acute biological effects of various oxovanadium species: a comparative study.
Topics: Kinetics; Organometallic Compounds; Phenanthrolines; Phosphoproteins; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Vanadates | 1998 |
Free radical stimulation of tyrosine kinase and phosphatase activity in human peripheral blood mononuclear cells.
Topics: Catalase; Enzyme Inhibitors; Free Radicals; Humans; Hydrogen Peroxide; Lymphocytes; Metals; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Superoxides; Vanadates; Xanthine; Xanthine Oxidase | 1998 |
Regulation of mammary differentiation by extracellular matrix involves protein-tyrosine phosphatases.
Topics: Animals; Basement Membrane; Cell Differentiation; Cells, Cultured; Collagen; DNA-Binding Proteins; Extracellular Matrix; Female; Integrin beta1; Janus Kinase 2; Mammary Glands, Animal; Mice; Mice, Inbred ICR; Milk Proteins; Phosphotyrosine; Pregnancy; Prolactin; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Prolactin; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Vanadates | 1998 |
Cell growth inhibition by a novel vitamin K is associated with induction of protein tyrosine phosphorylation.
Topics: Carcinoma, Hepatocellular; Catechols; Cell Division; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Humans; Kinetics; Liver Neoplasms; Mercaptoethanol; Naphthoquinones; Nitriles; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sulfhydryl Compounds; Tumor Cells, Cultured; Tyrphostins; Vanadates; Vitamin K | 1998 |
Modulation of baroreflex sensitivity by the state of protein tyrosine phosphorylation in the brainstem of the rat.
Topics: Animals; Atropine; Baroreflex; Brain Stem; Enzyme Inhibitors; Genistein; Hemodynamics; Male; Muscarinic Antagonists; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Vanadates | 1998 |
Hormonal regulation of focal adhesions in bovine adrenocortical cells: induction of paxillin dephosphorylation by adrenocorticotropic hormone.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cattle; Cell Adhesion Molecules; Cell Size; Cells, Cultured; Colforsin; CSK Tyrosine-Protein Kinase; Cyclic AMP; Cytoskeletal Proteins; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Immunohistochemistry; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine; Vanadates | 1998 |
Hypotonic-stimulated taurine efflux in skate erythrocytes: regulation by tyrosine phosphatase activity.
Topics: Adenosine Triphosphate; Animals; Anion Exchange Protein 1, Erythrocyte; Enzyme Inhibitors; Erythrocytes; Hypotonic Solutions; Phosphotyrosine; Protein Tyrosine Phosphatases; Skates, Fish; Taurine; Vanadates | 1998 |
Stimulation of primed neutrophils by soluble immune complexes: priming leads to enhanced intracellular Ca2+ elevations, activation of phospholipase D, and activation of the NADPH oxidase.
Topics: Aniline Compounds; Antigen-Antibody Complex; Calcium; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroquinones; NADPH Oxidases; Neutrophils; Phospholipase D; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Reactive Oxygen Species; Respiratory Burst; Signal Transduction; Vanadates; Xanthenes | 1998 |
Increased tyrosine phosphorylation of band 3 in hemoglobinopathies.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Anion Exchange Protein 1, Erythrocyte; Antibodies; beta-Thalassemia; Erythrocyte Count; Erythrocytes; Hemoglobin SC Disease; Hemoglobinopathies; Humans; Immunoblotting; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Reticulocytes; Tyrosine; Vanadates | 1998 |
Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia.
Topics: Actins; Animals; Cadherins; Cell Line; Cell Membrane Permeability; Dogs; Genistein; Immunohistochemistry; Inulin; Kidney; Membrane Proteins; Nitriles; Peroxides; Phalloidine; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rhodamines; Staurosporine; Tight Junctions; Tyrphostins; Vanadates; Zonula Occludens-1 Protein | 1998 |
Characterisation of alpha-dystrobrevin in muscle.
Topics: Agrin; Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Cytoskeletal Proteins; Disease Models, Animal; Dystrophin-Associated Proteins; Fetus; Humans; Membrane Proteins; Mice; Mice, Inbred mdx; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Neuropeptides; Phosphotyrosine; Protein Isoforms; Synapses; Utrophin; Vanadates | 1998 |
Ex vivo evidence for asymmetric tyrosine phosphorylation of ZAP-70 on double-positive thymocytes in the positive selection process.
Topics: Animals; Antibodies, Monoclonal; beta 2-Microglobulin; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Histocompatibility Antigens; Isoenzymes; Major Histocompatibility Complex; Membrane Proteins; Mice; Mice, Transgenic; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocyte Subsets; Thymus Gland; Type C Phospholipases; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 1998 |
Alteration of phosphotyrosine-containing proteins during differentiation of chicken erythroleukemia cells (HD3).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Butyric Acid; Cell Differentiation; Chickens; Enzyme Inhibitors; Erythroblasts; Hemin; Hemoglobins; Leukemia, Erythroblastic, Acute; Neoplasm Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Vanadates | 1998 |
Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.
Topics: Androstadienes; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Jurkat Cells; NF-kappa B; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; src Homology Domains; Transcriptional Activation; Tumor Necrosis Factor-alpha; Vanadates; Wortmannin | 1999 |
Enteropathogenic Escherichia coli inhibits phagocytosis.
Topics: Animals; Cell Line; Enzyme Inhibitors; Escherichia coli; Kinetics; Macrophages; Mice; Phagocytosis; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Vanadates | 1999 |
The Csk homologous kinase, Chk, binds tyrosine phosphorylated paxillin in human blastic T cells.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Fractionation; Cell Membrane; Cells, Cultured; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Cytosol; Fibroblasts; Humans; Mice; Molecular Weight; Mutation; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; src Homology Domains; src-Family Kinases; T-Lymphocytes; Vanadates | 1999 |
Bcl-xL blocks activation of related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2 and stress-activated protein kinase/c-Jun N-terminal protein kinase in the cellular response to methylmethane sulfonate.
Topics: bcl-X Protein; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Focal Adhesion Kinase 2; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Methyl Methanesulfonate; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-delta; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Serpins; Stress, Physiological; Vanadates; Viral Proteins | 1999 |
Phosphotyrosine signalling as a regulator of neural crest cell adhesion and motility.
Topics: Animals; Benzoquinones; Cadherins; Cell Adhesion; Cell Culture Techniques; Cell Movement; Coturnix; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Genistein; Lactams, Macrocyclic; Neural Crest; Ouabain; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Sodium-Potassium-Exchanging ATPase; Vanadates | 1999 |
Complement-mediated injury reversibly disrupts glomerular epithelial cell actin microfilaments and focal adhesions.
Topics: Actin Cytoskeleton; Actins; Animals; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Complement Membrane Attack Complex; Complement System Proteins; Cycloheximide; Cytoskeletal Proteins; Epithelial Cells; Fluorescent Antibody Technique; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glomerulonephritis; Immunoglobulin G; Integrin alpha3beta1; Integrins; Kidney Glomerulus; Paxillin; Phosphoproteins; Phosphotyrosine; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Rats; Receptors, Laminin; Talin; Vanadates; Vinculin | 1999 |
Gi-mediated activation of mitogen-activated protein kinase (MAPK) pathway by receptor mimetic basic secretagogues of connective tissue-type mast cells: bifurcation of arachidonic acid-induced release upstream of MAPK.
Topics: Androstadienes; Animals; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Chromones; Connective Tissue Cells; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Histamine Release; In Vitro Techniques; Indole Alkaloids; Inositol Phosphates; Kinetics; Mast Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; p-Methoxy-N-methylphenethylamine; Pertussis Toxin; Phosphotyrosine; Rats; Rats, Wistar; Signal Transduction; Tyrphostins; Vanadates; Virulence Factors, Bordetella; Wortmannin | 1999 |
Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31.
Topics: Amino Acid Sequence; Binding Sites; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Molecular Sequence Data; Monocytes; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phospholipase C gamma; Phosphopeptides; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Platelet Endothelial Cell Adhesion Molecule-1; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Surface Plasmon Resonance; Type C Phospholipases; Vanadates | 1999 |
Regulation of endothelial cell myosin light chain kinase by Rho, cortactin, and p60(src).
Topics: Actins; Animals; Biological Transport; Cattle; Cortactin; Cytoskeleton; Endothelium; Enzyme Inhibitors; GTP Phosphohydrolases; Humans; Lung; Microfilament Proteins; Myosin-Light-Chain Kinase; Myosins; Oncogene Protein pp60(v-src); Peroxides; Phosphorylation; Phosphotyrosine; rho GTP-Binding Proteins; Vanadates | 1999 |
Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.
Topics: Arsenicals; Cell Nucleus; Copper; Diamide; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; Hydrogen Peroxide; Iron; Lymphocytes; Oxidative Stress; Phenanthrolines; Phosphorylation; Phosphotyrosine; Phytohemagglutinins; Protein Tyrosine Phosphatases; Reactive Oxygen Species; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1999 |
Increased tyrosine kinase activity but not calcium mobilization is required for ceramide-induced apoptosis.
Topics: Animals; Apoptosis; Calcimycin; Calcium; Cell Line; Ceramides; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Fibroblasts; Genistein; Insulin; Insulin-Like Growth Factor I; Lysophospholipids; Mice; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, IGF Type 1; Signal Transduction; Sphingosine; Thapsigargin; Vanadates | 1999 |
Insulin signaling is inhibited by micromolar concentrations of H(2)O(2). Evidence for a role of H(2)O(2) in tumor necrosis factor alpha-mediated insulin resistance.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Catalase; Cell Line; Enzyme Inhibitors; Glucose; Humans; Hydrogen Peroxide; Hyperglycemia; Insulin; Insulin Resistance; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptor, Insulin; Signal Transduction; Tumor Necrosis Factor-alpha; Vanadates | 1999 |
Induction of endothelial monolayer permeability by phosphatidate.
Topics: Animals; Benzoquinones; Calcium; Cattle; Cell Membrane Permeability; Cells, Cultured; Diglycerides; Endothelium, Vascular; Enzyme Activation; Evans Blue; Lactams, Macrocyclic; Lipids; Lysophospholipids; Neutrophils; Phosphatidic Acids; Phospholipase D; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Pulmonary Artery; Quinones; Rifabutin; Vanadates | 1999 |
Laminin stimulates protein tyrosine dephosphorylation in PC12 cells.
Topics: Animals; Aurintricarboxylic Acid; Enzyme Inhibitors; Genistein; Kinetics; Laminin; PC12 Cells; Phenols; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quercetin; Rats; Signal Transduction; Vanadates | 1999 |
Insulin-induced stimulation of Na+,K(+)-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the alpha-subunit at Tyr-10.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Enzyme Activation; Genistein; Insulin; Insulin Antagonists; Kidney Tubules, Proximal; Male; Opossums; Ouabain; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Transfection; Tyrosine; Vanadates | 1999 |
Early effects of protein kinase modulators on DNA synthesis in rat cerebral cortex.
Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Camptothecin; Cerebral Cortex; Dimethyl Sulfoxide; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Genistein; Lactams, Macrocyclic; Naphthalenes; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Staurosporine; Steroids; Vanadates | 1999 |
Tyrosine phosphorylation regulates rapid endocytosis in adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin Cells; Endocytosis; Enzyme Inhibitors; Exocytosis; Intercellular Signaling Peptides and Proteins; Kinetics; Peptides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tyrphostins; Vanadates; Zinc | 1999 |
Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.
Topics: Actins; Arsenicals; Cell Adhesion Molecules; Cell Movement; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Glioma; Humans; Matrix Metalloproteinases; Neoplasm Invasiveness; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 1999 |
Association of the tyrosine phosphatase SHP-2 with transducin-alpha and a 97-kDa tyrosine-phosphorylated protein in photoreceptor rod outer segments.
Topics: Animals; Cattle; Enzyme Inhibitors; Eye Proteins; Intracellular Signaling Peptides and Proteins; Macromolecular Substances; Membrane Proteins; Molecular Weight; Molybdenum; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Rod Cell Outer Segment; Subcellular Fractions; Transducin; Vanadates | 1999 |
Bis(N,N-dimethylhydroxamido)hydroxooxovanadate inhibition of protein tyrosine phosphatase activity in intact cells: comparison with vanadate.
Topics: 3T3 Cells; Animals; Biological Transport; CHO Cells; Cricetinae; Enzyme Inhibitors; Glucose; Glycogen; Humans; Jurkat Cells; Mice; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptor, Insulin; Vanadates | 1999 |
Involvement of the membrane distal catalytic domain in pervanadate-induced tyrosine phosphorylation of receptor protein-tyrosine phosphatase alpha.
Topics: Catalytic Domain; Cell Membrane; Enzyme Inhibitors; Humans; Mutagenesis, Site-Directed; Neuroectodermal Tumors, Primitive, Peripheral; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Regulation of T cell receptor- and CD28-induced tyrosine phosphorylation of the focal adhesion tyrosine kinases Pyk2 and Fak by protein kinase C. A role for protein tyrosine phosphatases.
Topics: Antigens, CD; CD28 Antigens; Cell Adhesion Molecules; Cells, Cultured; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Humans; Jurkat Cells; Kinetics; Phorbols; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Vanadates | 2000 |
Phosphorylation-dependent regulation of skeletogenesis in sea urchin micromere-derived cells and embryos.
Topics: Animals; Bone and Bones; Cell Differentiation; Cells, Cultured; Collagen; Embryo, Nonmammalian; Enzyme Inhibitors; Genistein; Morphogenesis; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA, Messenger; Sea Urchins; Vanadates | 1999 |
Inhibition of phosphatidylserine synthesis during Jurkat T cell activation. The phosphatase inhibitor, sodium ortho-vanadate bypasses the CD3/T cell receptor-induced second messenger signaling pathway.
Topics: Antibodies, Monoclonal; Calcium; Calcium Signaling; Calcium-Transporting ATPases; CD3 Complex; Cytosol; Diglycerides; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphatidylserines; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Receptors, Antigen, T-Cell; Second Messenger Systems; Substrate Specificity; T-Lymphocytes; Vanadates | 2000 |
Tyrosine phosphorylation of myelin P(0) and its implication in signal transduction.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Brain; Cell Line; Cloning, Molecular; Consensus Sequence; Humans; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Myelin P0 Protein; Neurilemmoma; Phenylalanine; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Sequence Alignment; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Restrictive endothelial barrier function during normal angiogenesis in vivo: partial dependence on tyrosine dephosphorylation of beta-catenin.
Topics: Allantois; Animals; Antigens, CD; beta Catenin; Cadherins; Capillary Permeability; Cell Differentiation; Chick Embryo; Chorion; Cytoskeletal Proteins; Dextrans; Endothelium, Vascular; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Neovascularization, Physiologic; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Trans-Activators; Vanadates | 2000 |
Activation of tyrosine kinase pathway by vanadate in gallbladder smooth muscle.
Topics: Animals; Biological Transport; Calcium; Cell Membrane; Enzyme Activation; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Vanadates | 2000 |
Disruption of microtubules in living cells by tyrphostin AG-1714.
Topics: Animals; Cell Line; Dimerization; Enzyme Inhibitors; Humans; Mice; Microtubules; Paclitaxel; Phosphorylation; Phosphotyrosine; Tyrphostins; Vanadates | 2000 |
Tyrosine phosphorylation of a 34-kDa protein induced by cross-linking a novel glycosylphosphatidylinositol-anchored glycoprotein (GPI-80) on human neutrophils that may regulate their adherence and migration.
Topics: Amidohydrolases; Androstadienes; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Chelating Agents; Cross-Linking Reagents; Cytochalasin B; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Genistein; GPI-Linked Proteins; Humans; Hydrolases; Indoles; Mice; Mice, Inbred BALB C; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Signal Transduction; Time Factors; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Syk-dependent phosphorylation of microtubules in activated B-lymphocytes.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Biopolymers; Cell Line; Centrosome; Chickens; Cytoskeleton; Enzyme Inhibitors; Enzyme Precursors; Gene Deletion; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Microtubules; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Syk Kinase; Tubulin; Vanadates | 2000 |
Synthesis, characterization and bioactivity of a new VO2+/aspirin complex.
Topics: Animals; Aspirin; Blotting, Western; Bone and Bones; Cell Differentiation; Cell Division; Cells, Cultured; Humans; Osteoblasts; Phosphorylation; Phosphotyrosine; Spectrophotometry, Infrared; Vanadates | 2000 |
Selective phosphotyrosine phosphatase inhibition and increased ceramide formation is associated with B-cell death by apoptosis.
Topics: Apoptosis; B-Lymphocytes; Cell Line; Ceramides; Humans; In Situ Nick-End Labeling; Jurkat Cells; Organ Specificity; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyrones; Sphingomyelins; Sphingosine; T-Lymphocytes; Vanadates | 2000 |
Involvement of tyrosine kinase activity in 1alpha,25(OH)2-vitamin D3 signal transduction in skeletal muscle cells.
Topics: Animals; Benzoquinones; Calcitriol; Calcium; Calcium Signaling; Cells, Cultured; Chick Embryo; DNA; Enzyme Activation; Flavonoids; Genistein; Isoenzymes; Lactams, Macrocyclic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-myc; Quinones; Rifabutin; Signal Transduction; Type C Phospholipases; Vanadates | 2000 |
The upregulating effect of insulin and vanadate on cell surface insulin receptors in rat adipocytes is modulated by glucose and energy availability.
Topics: Adipocytes; Animals; Biological Transport; Cell Membrane; Cytochalasin B; Energy Metabolism; Enzyme Inhibitors; Genistein; Glucose; Glycosylation; Humans; Insulin; Kinetics; Male; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Tunicamycin; Vanadates | 2000 |
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.
Topics: Amino Acid Substitution; Antigens, CD; Antigens, Surface; Binding Sites; Cell Line; Cytoplasm; Desmosomes; Enzyme Inhibitors; Humans; Integrin alpha6; Integrin alpha6beta4; Integrin beta4; Integrins; Phenylalanine; Phosphopeptides; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Signal Transduction; src Homology Domains; Transfection; Tyrosine; Vanadates | 2001 |
Peroxovanadate induces tyrosine phosphorylation of phosphoinositide-dependent protein kinase-1 potential involvement of src kinase.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adipocytes; Animals; Cells, Cultured; Kinetics; Male; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Recombinant Proteins; src-Family Kinases; Transfection; Vanadates | 2000 |
Diperoxovanadate alters endothelial cell focal contacts and barrier function: role of tyrosine phosphorylation.
Topics: Actins; Animals; Antigens, CD; Cadherins; Capillary Permeability; Cattle; Cell Adhesion Molecules; Cell Communication; Cell Line; Electric Impedance; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Antibody Technique; Mitogen-Activated Protein Kinases; Peroxides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 2000 |
Shf, a Shb-like adapter protein, is involved in PDGF-alpha-receptor regulation of apoptosis.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Apoptosis; Cell Division; Cloning, Molecular; Female; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Molecular Sequence Data; Phosphoproteins; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Receptor, Platelet-Derived Growth Factor alpha; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; src Homology Domains; Vanadates | 2000 |
The Src kinase p56(lck) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin.
Topics: Blotting, Western; Cell Adhesion; Dose-Response Relationship, Drug; Endothelium; Enzyme Inhibitors; Fibronectins; Flow Cytometry; Humans; Integrin alpha4beta1; Integrins; Interleukin-2; Jurkat Cells; Kinetics; Ligands; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Phosphotyrosine; Protein Binding; Receptors, Lymphocyte Homing; Signal Transduction; T-Lymphocytes; Up-Regulation; Vanadates; Vascular Cell Adhesion Molecule-1 | 2001 |
Role of receptor protein tyrosine phosphatase alpha (RPTPalpha) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels.
Topics: Animals; Enzyme Inhibitors; Female; Gene Expression; Genistein; Humans; Kinetics; Kv1.1 Potassium Channel; Kv1.2 Potassium Channel; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Phosphotyrosine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Receptors, Serotonin; Serotonin; Transfection; Vanadates; Xenopus laevis | 2000 |
Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases.
Topics: DNA; DNA-Binding Proteins; Enzyme Activation; Humans; Hydrogen Peroxide; I-kappa B Proteins; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Signal Transduction; src Homology Domains; Stilbenes; T-Lymphocytes; Transcriptional Activation; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2001 |
Ultraviolet radiation inhibits interleukin-2-induced tyrosine phosphorylation and the activation of STAT5 in T lymphocytes.
Topics: Animals; DNA-Binding Proteins; Gene Expression Regulation; Interleukin-2; Lymphocyte Activation; Mice; Milk Proteins; Phosphorylation; Phosphotyrosine; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; STAT5 Transcription Factor; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Trans-Activators; Transcription, Genetic; Ultraviolet Rays; Up-Regulation; Vanadates | 2001 |
Mac-1-dependent tyrosine phosphorylation during neutrophil adhesion.
Topics: Antibodies, Monoclonal; Cell Adhesion; Cytochalasin B; Enzyme Inhibitors; Fibrinogen; Genistein; Glutathione Transferase; Humans; In Vitro Techniques; Interleukin-8; Kinetics; Macrophage-1 Antigen; Neutrophil Activation; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; src Homology Domains; Staurosporine; Tetradecanoylphorbol Acetate; Vanadates | 2001 |
Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases.
Topics: Amino Acid Substitution; Antibodies, Monoclonal; CD3 Complex; CD5 Antigens; Enzyme Activation; Humans; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mutation; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Fusion Proteins; T-Lymphocytes; Transfection; Tyrosine; Vanadates | 2001 |
A model of activation of the protein tyrosine phosphatase SHP-2 by the human leptin receptor.
Topics: Binding Sites; Carrier Proteins; Catalytic Domain; Enzyme Activation; Escherichia coli; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Models, Chemical; Neuroblastoma; Peptide Fragments; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Cell Surface; Receptors, Leptin; Recombinant Fusion Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Tumor Cells, Cultured; Vanadates | 2001 |
Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts.
Topics: Antigens, Polyomavirus Transforming; Cells, Cultured; CSK Tyrosine-Protein Kinase; Humans; Jurkat Cells; Lymphocyte Activation; Membrane Microdomains; Models, Biological; Muromonab-CD3; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Proteins; src Homology Domains; src-Family Kinases; T-Lymphocytes; Transfection; Vanadates | 2001 |
Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-delta in hemopoietic cells.
Topics: Acetophenones; Animals; B-Lymphocytes; Benzopyrans; Cells, Cultured; Enzyme Inhibitors; Hematopoietic Stem Cells; Isoenzymes; Mast Cells; Mice; Mice, Knockout; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Kinase C-delta; Protein Tyrosine Phosphatases; Receptors, IgE; Tumor Cells, Cultured; Vanadates | 2001 |
Tyrosine phosphorylation following alterations in arteriolar intraluminal pressure and wall tension.
Topics: Angiotensin II; Animals; Antibody Specificity; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Colforsin; Endothelium, Vascular; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Physical Stimulation; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrphostins; Vanadates; Vasoconstriction; Vasodilator Agents; Verapamil | 2001 |
Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin.
Topics: Animals; Cell Line; Cricetinae; DNA-Binding Proteins; Drug Antagonism; Enzyme Inhibitors; Humans; Interferon-gamma; Interleukin-6; Intracellular Signaling Peptides and Proteins; Oncostatin M; Peptides; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Thrombin; Trans-Activators; Vanadates | 2001 |
Modulation of nicotinic acetylcholine receptor turnover by tyrosine phosphorylation in rat myotubes.
Topics: Animals; Biotinylation; Bungarotoxins; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Iodine Radioisotopes; Muscle Fibers, Skeletal; Neuromuscular Junction; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tyrosine; Vanadates | 2001 |
Differential involvement of Src family kinases in pervanadate-mediated responses in rat myometrial cells.
Topics: Animals; Cells, Cultured; DNA; Enzyme Inhibitors; Female; Inositol Phosphates; Isoenzymes; Kinetics; Mitogen-Activated Protein Kinases; Myometrium; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Type C Phospholipases; Vanadates | 2002 |
SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor.
Topics: Binding Sites; Blotting, Western; Cells, Cultured; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Transfection; Tyrosine; Vanadates | 2002 |
Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation.
Topics: Breast Neoplasms; Cell Line, Transformed; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Isoenzymes; Oligonucleotides, Antisense; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor, EphA2; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
Angiotensin II effects on STAT3 phosphorylation in cardiomyocytes: evidence for Erk-dependent Tyr705 dephosphorylation.
Topics: Angiotensin II; Animals; Animals, Newborn; DNA-Binding Proteins; Flavonoids; Interleukin-6; Leukemia Inhibitory Factor; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Phosphorylation; Phosphotyrosine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Vanadates | 2003 |
Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.
Topics: Adherens Junctions; Animals; Antigens, CD; beta Catenin; Cadherins; Capillaries; Carbon Radioisotopes; Cattle; Cell Movement; Chromium Radioisotopes; Cytoskeletal Proteins; Desmoplakins; Endothelium, Vascular; Enzyme Inhibitors; Neovascularization, Physiologic; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pulmonary Artery; Serum Albumin, Bovine; Trans-Activators; Tyrosine; Vanadates | 2003 |
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 activity exerts an antidiabetic action in Goto-Kakizaki rats.
Topics: Adipocytes; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Biological Transport; Blood Glucose; Cell Adhesion Molecules; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucose; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Muscle, Skeletal; Peroxides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Recombinant Proteins; Vanadates | 2003 |
Activation of phospholipase D is not mediated by direct phosphorylation on tyrosine residues.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; PC12 Cells; Phospholipase D; Phosphorylation; Phosphotyrosine; Precipitin Tests; Rats; Tyrosine; Vanadates | 2003 |
Involvement of the tyrosine phosphorylation on GSH transport in NIH3T3 fibroblasts.
Topics: Animals; Biological Transport; Fibroblasts; Glucose; Glutathione; Hydrogen Peroxide; Mice; Mutation; NIH 3T3 Cells; Oxidants; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Tyrosine; Vanadates | 2003 |
Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Catalysis; Enzyme Inhibitors; Histidine; Humans; Hydrolysis; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nitrophenols; Organophosphorus Compounds; Peptides; Phenylalanine; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 3; Protein Tyrosine Phosphatases; Sequence Alignment; Vanadates | 2004 |
Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes.
Topics: Angiotensin II; Animals; Blotting, Western; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Imidazoles; Immunoblotting; Kidney; Oligopeptides; Phosphorylation; Phosphotyrosine; Pyridines; Rats; Rats, Inbred WKY; Signal Transduction; Tyrosine; Vanadates | 2003 |
The protein tyrosine phosphatase CD45 is required for interleukin 6 signaling in U266 myeloma cells.
Topics: Actins; Antigens, CD; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Separation; Coculture Techniques; Cytokine Receptor gp130; DNA-Binding Proteins; Humans; Interleukin-6; Leukocyte Common Antigens; Membrane Glycoproteins; Multiple Myeloma; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stromal Cells; Trans-Activators; Vanadates | 2004 |
Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats.
Topics: Animals; Animals, Genetically Modified; Blotting, Western; Calcium; Calcium Chloride; Calcium-Binding Proteins; Calmodulin; Carboxylic Ester Hydrolases; Chelating Agents; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Gene Dosage; Intracellular Signaling Peptides and Proteins; Male; Microsomes, Liver; Okadaic Acid; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfotransferases; Trifluoperazine; Vanadates | 2004 |
Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cytoskeleton; Cytosol; Golgi Apparatus; Guanine Nucleotide-Releasing Factor 2; HeLa Cells; Humans; Microscopy, Fluorescence; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; Structure-Activity Relationship; Subcellular Fractions; Vanadates | 2004 |
FLT3/ITD mutation signaling includes suppression of SHP-1.
Topics: Acute Disease; Carbazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; fms-Like Tyrosine Kinase 3; Furans; Humans; Hydrolysis; Indoles; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Mutation; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA Interference; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Vanadates | 2005 |
Characterization of a plant, tyrosine-specific phosphatase of the aspartyl class.
Topics: Animals; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Binding Sites; Catalysis; DNA Mutational Analysis; Drosophila Proteins; Enzyme Inhibitors; Eye Proteins; Hydrogen-Ion Concentration; Metals, Heavy; Peptide Fragments; Peptides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Structural Homology, Protein; Substrate Specificity; Tungsten Compounds; Vanadates | 2005 |
Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues.
Topics: Animals; Cadherins; Cell Extracts; Cell Line; Endothelial Cells; Endothelium, Vascular; Female; Gonadotropins, Equine; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Ovary; Phosphorylation; Phosphotyrosine; Proteins; Proto-Oncogene Proteins pp60(c-src); Umbilical Veins; Uterus; Vanadates; Vascular Endothelial Growth Factor Receptor-2 | 2005 |
Two-stage affinity purification for inducibly phosphorylated membrane proteins.
Topics: Animals; Antibodies; Biotinylation; Cell Compartmentation; Cell Line; Electrophoresis, Polyacrylamide Gel; Hybridomas; Immunoprecipitation; Isoelectric Focusing; Macrophages; Mass Spectrometry; Membrane Proteins; Mice; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Proteome; T-Lymphocytes; Vanadates | 2005 |
Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues.
Topics: Cell Line, Tumor; Cell Proliferation; Cloning, Molecular; Colorectal Neoplasms; Culture Media, Serum-Free; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Fluorescence Resonance Energy Transfer; Humans; Immunoblotting; Immunoprecipitation; Kinetics; Microscopy, Confocal; Microscopy, Fluorescence; Phosphorylation; Phosphotyrosine; Receptor Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Time Factors; Vanadates | 2005 |
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.
Topics: Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Animals; Brain; Brain Chemistry; Cell Line, Tumor; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Female; Fetal Proteins; Humans; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neuroblastoma; Neurofibrillary Tangles; Neurons; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-fyn; src-Family Kinases; tau Proteins; Transfection; Vanadates | 2005 |
B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs.
Topics: Amino Acid Motifs; Animals; CD28 Antigens; CD4-Positive T-Lymphocytes; Cell Proliferation; Dimerization; Growth Inhibitors; Humans; Interleukin-2; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Mice; Mutation; Phosphotyrosine; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Immunologic; Recombinant Fusion Proteins; Signal Transduction; Vanadates | 2006 |
Chromium and vanadate combination increases insulin-induced glucose uptake by 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Chromium; Glucose; Insulin; Mice; Phosphotyrosine; Receptor, Insulin; Signal Transduction; Vanadates | 2006 |
Sodium orthovanadate induced tyrosine phosphorylation of platelet nitric oxide synthase negatively regulates enzyme activity.
Topics: Animals; Blood Platelets; Cattle; Cells, Cultured; Cyclic GMP; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphotyrosine; Protein Binding; src-Family Kinases; Vanadates | 2006 |
The Grb2/Mek pathway represses Nanog in murine embryonic stem cells.
Topics: Animals; Biomarkers; Cell Differentiation; Cell Line; DNA-Binding Proteins; Embryo, Mammalian; Gene Expression Regulation; GRB2 Adaptor Protein; Homeodomain Proteins; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Nanog Homeobox Protein; Phosphotyrosine; Protein Kinase Inhibitors; Stem Cells; Transcription, Genetic; Vanadates | 2006 |
Enhancement of insulin signaling pathway in adipocytes by oxovanadium(IV) complexes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Membrane; Diabetes Mellitus; Glucose Transporter Type 4; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypoglycemia; Insulin; Male; Mice; Molecular Structure; Phosphorylation; Phosphotyrosine; Picolinic Acids; Protein Transport; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Signal Transduction; Vanadates | 2006 |
Involvement of insulin-like growth factor type 1 receptor and protein kinase Cdelta in bis(maltolato)oxovanadium(IV)-induced phosphorylation of protein kinase B in HepG2 cells.
Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin Receptor Substrate Proteins; Oligonucleotides, Antisense; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C-delta; Proto-Oncogene Proteins c-akt; Pyrones; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction; Tyrphostins; Vanadates | 2006 |
Tyrosine phosphatase and cytochrome P450 activity are critical in regulating store-operated calcium channels in human fibroblasts.
Topics: Bradykinin; Calcium; Calcium Channels; Cells, Cultured; Cyclic GMP; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Econazole; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Humans; Nitric Oxide; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Vanadates | 2006 |
Evaluation of enrichment techniques for mass spectrometry: identification of tyrosine phosphoproteins in cancer cells.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Cell Line, Tumor; Chromatography, Affinity; Chromatography, Liquid; Humans; Immunoprecipitation; Mass Spectrometry; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Phosphoproteins; Phosphotyrosine; Vanadates | 2007 |
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach.
Topics: Amino Acid Sequence; Cell Adhesion; Enzyme Inhibitors; ErbB Receptors; HeLa Cells; Humans; Isotope Labeling; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2007 |
Regulation of airway goblet cell mucin secretion by tyrosine phosphorylation signaling pathways.
Topics: Adenosine Triphosphate; Cells, Cultured; Epithelial Cells; Estrenes; Genistein; Goblet Cells; Humans; Mucins; Phosphorylation; Phosphotyrosine; Protein Kinase C-delta; Protein Kinase Inhibitors; Pyrrolidinones; Respiratory System; Signal Transduction; Time Factors; Type C Phospholipases; Vanadates | 2007 |
Preformed STAT3 transducer complexes in human HepG2 cells and rat hepatocytes.
Topics: Actins; Animals; Caveolins; Cell Line, Tumor; Cell Membrane; Cell Separation; Cholesterol; Cytoskeleton; Detergents; Hepatocytes; Humans; Interleukin-6; Male; Multiprotein Complexes; Phosphotyrosine; Rats; Signal Transduction; Solubility; STAT3 Transcription Factor; Subcellular Fractions; Tubulin; Vanadates | 2007 |
Paxillin phosphorylation controls invadopodia/podosomes spatiotemporal organization.
Topics: Animals; Calpain; Cell Communication; Cell Movement; Cell Transformation, Viral; Cricetinae; Enzyme Activation; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; Mice; Mutant Proteins; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Pseudopodia; Rous sarcoma virus; Vanadates | 2008 |
Both EGFR kinase and Src-related tyrosine kinases regulate human ether-à-go-go-related gene potassium channels.
Topics: Cell Line; ErbB Receptors; Ether-A-Go-Go Potassium Channels; Genistein; Humans; Ion Channel Gating; Phosphotyrosine; Point Mutation; Pyrimidines; src-Family Kinases; Tyrphostins; Vanadates | 2008 |
The mixed-lineage kinase DLK undergoes Src-dependent tyrosine phosphorylation and activation in cells exposed to vanadate or platelet-derived growth factor (PDGF).
Topics: Animals; Apoptosis Regulatory Proteins; Becaplermin; Calcium-Calmodulin-Dependent Protein Kinases; Chlorocebus aethiops; COS Cells; Cyclosporine; Death-Associated Protein Kinases; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Mice; NIH 3T3 Cells; Okadaic Acid; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Rats; Recombinant Fusion Proteins; RNA Interference; src-Family Kinases; Vanadates | 2009 |
Modulation of bovine sperm signalling pathways: correlation between intracellular parameters and sperm capacitation and acrosome exocytosis.
Topics: 1-Methyl-3-isobutylxanthine; Acrosome Reaction; Animals; Arsenicals; Calcium; Cattle; Cell Survival; Chlortetracycline; Cyclic AMP; Exocytosis; Heparin; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Phosphodiesterase Inhibitors; Phosphotyrosine; Protein Tyrosine Phosphatases; Reproductive Techniques; Signal Transduction; Sperm Capacitation; Spermatozoa; Time Factors; Vanadates | 2009 |
Cryopreservation affects bovine sperm intracellular parameters associated with capacitation and acrosome exocytosis.
Topics: 1-Methyl-3-isobutylxanthine; Acrosome Reaction; Animals; Arsenicals; Calcium; Cattle; Cell Survival; Chlortetracycline; Cryopreservation; Cyclic AMP; Exocytosis; Heparin; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Phosphodiesterase Inhibitors; Phosphotyrosine; Protein Tyrosine Phosphatases; Reproductive Techniques; Semen Preservation; Signal Transduction; Sperm Capacitation; Sperm Motility; Spermatozoa; Time Factors; Vanadates | 2009 |
Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.
Topics: Apoptosis; Benzenesulfonates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin E; DNA, Neoplasm; Glioblastoma; Humans; Interleukin-6; Janus Kinase 1; Janus Kinase 2; Mutant Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Niacinamide; Oncogene Proteins; Phenylurea Compounds; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Signal Transduction; Sorafenib; src-Family Kinases; STAT3 Transcription Factor; Tumor Cells, Cultured; Vanadates | 2010 |
Tyrosine phosphorylation modulates store-operated calcium entry in cultured rat epididymal basal cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Epididymis; Male; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Thapsigargin; Vanadates | 2011 |
TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells.
Topics: Cell Differentiation; Cell Line, Tumor; Colforsin; Golgi Apparatus; Guanine Nucleotide-Releasing Factor 2; HEK293 Cells; Humans; Mutant Proteins; Neurites; Neuroblastoma; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 2; src-Family Kinases; Structure-Activity Relationship; Vanadates | 2011 |
Regulation of muscle acetylcholine receptor turnover by β subunit tyrosine phosphorylation.
Topics: Agrin; Animals; Cell Membrane; Cells, Cultured; Half-Life; Mice; Mice, Transgenic; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Neuromuscular Junction; Phosphorylation; Phosphotyrosine; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein Stability; Protein Subunits; Receptors, Nicotinic; Recombinant Fusion Proteins; Synapses; Vanadates | 2013 |
The Streptococcus thermophilus protein Wzh functions as a phosphotyrosine phosphatase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Enzyme Inhibitors; Escherichia coli; Molecular Sequence Data; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Streptococcus thermophilus; Vanadates | 2013 |
B7-H5 costimulates human T cells via CD28H.
Topics: Amino Acid Sequence; Animals; B7 Antigens; CD28 Antigens; Coculture Techniques; Epitopes; Fluoresceins; Gene Expression Regulation; Genome, Human; HEK293 Cells; Humans; Ligands; Lymphocyte Activation; Membrane Proteins; Mice; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Binding; Signal Transduction; Succinimides; T-Lymphocytes; Vanadates | 2013 |
Tyrphostin AG556 increases the activity of large conductance Ca
Topics: Animals; Basilar Artery; Cell Separation; Epidermal Growth Factor; ErbB Receptors; Genistein; HEK293 Cells; Humans; Indoles; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Male; Myocytes, Smooth Muscle; Phosphorylation; Phosphotyrosine; Protein Subunits; Rats, Sprague-Dawley; Tyrphostins; Vanadates; Vasodilation | 2017 |
Crk adaptor proteins regulate CD3ζ chain phosphorylation and TCR/CD3 down-modulation in activated T cells.
Topics: Animals; Antibodies; CD3 Complex; Chlorocebus aethiops; COS Cells; Cross-Linking Reagents; Down-Regulation; Humans; Jurkat Cells; Lymphocyte Activation; Mice; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins c-crk; Receptors, Antigen, T-Cell; src Homology Domains; T-Lymphocytes; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2017 |
Tandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome.
Topics: Humans; Ions; Jurkat Cells; Phosphopeptides; Phosphoproteins; Phosphotyrosine; Proteome; Proteomics; Tandem Mass Spectrometry; Vanadates | 2020 |
Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr
Topics: Alkaline Phosphatase; Amino Acid Sequence; Antibodies; Cell Line; Cell Line, Tumor; Humans; Leucine; Methylation; Mutation; Peptides; Phosphorylation; Phosphotyrosine; Protein Phosphatase 2; Protein Processing, Post-Translational; Research; Vanadates | 2020 |
PP2A
Topics: Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal; Antibody Specificity; Cross Reactions; Epidermal Growth Factor; HEK293 Cells; Humans; Leucine; Lymphocyte Activation; Methylation; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Peptides; Phosphorylation; Phosphotyrosine; Protein Phosphatase 2; Protein Processing, Post-Translational; src-Family Kinases; T-Lymphocytes; Vanadates | 2020 |