phosphotyrosine has been researched along with serine in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (37.50) | 18.7374 |
| 1990's | 21 (37.50) | 18.2507 |
| 2000's | 10 (17.86) | 29.6817 |
| 2010's | 2 (3.57) | 24.3611 |
| 2020's | 2 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, RJ; Latour, DA; Raden, DL; Stanley, K; Theroux, SJ | 1 |
| Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P | 1 |
| Anderson, SR; Malencik, DA; Zhao, ZZ | 1 |
| Iwashita, S; Mitsui, K | 1 |
| Kim, HK; Kim, JG; Kim, JW; Margolis, B; Rhee, SG; Schlessinger, J; Zilberstein, A | 1 |
| Kanner, SB; Parsons, JT; Reynolds, AB; Vines, RR; Wang, HC | 1 |
| Klee, U; Singh, TJ | 1 |
| Aitken, A; Morrice, N | 1 |
| Blumenthal, DK; Chan, CP; Gallis, B; Krebs, EG; Pallen, CJ; Wang, JH | 1 |
| Etheredge, RW; Glimcher, MJ | 1 |
| Bauer, H; Niemann, H; Simon, E; Snoek, GT; Tamura, T | 1 |
| David-Pfeuty, T; Guesdon, F | 1 |
| Colca, JR; McCroskey, MC; Pearson, JD | 1 |
| Sale, GJ; Smith, DM | 1 |
| Beachey, EH; Kotb, M | 1 |
| Boland, D; Goren, HJ; Neufeld, E | 1 |
| Gjika, HB; Levine, L; Van Vunakis, H | 1 |
| Blomberg, J; Nalewaik, RP; Reynolds, FH; Stephenson, JR; Van de Ven, WJ | 1 |
| Sen, A | 1 |
| Blith, DL; Häring, HU; Kahn, CR; Karlsson, FA; Kasuga, M; Zick, Y | 1 |
| Fujitaki, JM; Smith, RA; Yang, JC | 1 |
| Cozzone, AJ; Manai, M | 1 |
| Congote, LF | 1 |
| Capony, JP; Demaille, JG | 1 |
| Chang, WC; Chou, CK; Lee, ML; Lee, SC | 1 |
| Buss, JE; Stull, JT | 1 |
| De Groot, N; Galski, H; Hochberg, AA; Ilan, J | 1 |
| Martensen, TM | 1 |
| Hakomori, S; Igarashi, Y; Kitamura, K; Zhou, Q | 1 |
| Desiderio, S; Malek, SN | 1 |
| Asamoah, KA; Carter, WG; Sale, GJ | 1 |
| Darnell, JE; Wen, Z; Zhong, Z | 1 |
| Chung, J; Park, I; Shin, J; Strominger, JL; Walsh, CT; Yun, Y | 1 |
| Buchwald, AB; Kreuzer, H; Meyer, T; Unterberg, C | 1 |
| Asamoah, KA; Atkinson, PG; Carter, WG; Sale, GJ | 1 |
| Ullrich, A; Vogel, W | 1 |
| Barford, D; Burke, TR; Chen, L; Jia, Z; Wang, S; Yan, X; Ye, B; Zhang, ZY | 1 |
| Chen, RH; Derynck, R; Feng, XH; Griswold-Prenner, I; Lawler, S; Maruoka, EM; Turck, CW | 1 |
| De Fea, K; Roth, RA | 1 |
| Alessi, DR; Cohen, P; Shaw, M | 1 |
| Corbin, J; Imagawa, T; Kaya, S; Kikkawa, U; Mårdh, S; Mori, M; Shimada, A; Taniguchi, K; Togawa, K | 1 |
| Cesaro, L; Marin, O; Meggio, F; Pagano, MA; Pinna, LA; Sarno, S | 1 |
| Gandour, RD; Kennelly, PJ; Meadows, CA; Potts, M; Savle, PS; Shelton, TE | 1 |
| Goodier, JL; Huang, Y; Intine, RV; Koduru, SB; Maraia, RJ; Phan, L; Pierstorff, E; Sakulich, AL | 1 |
| Decker, T; Kovarik, J; Steinlein, P; Stockinger, S; Stoiber, D | 1 |
| Furukawa, T; Ichijo, T; Kawakami, N; Saito, H; Tsujikawa, K; Uchino, Y; Yamamoto, H | 1 |
| Dittmann, KH; Mayer, C; Rodemann, HP | 1 |
| Ridyard, MS; Robbins, SM | 1 |
| Bouzakri, K; Espinosa, S; Gual, P; Guebre-Egziabher, F; Laville, M; Le Marchand-Brustel, Y; Riou, JP; Roques, M; Tanti, JF; Vidal, H | 1 |
| Boura-Halfon, S; Herschkovitz, A; Leroith, D; Liu, YF; Paz, K; Ronen, D; Zick, Y | 1 |
| Helling, S; Kadenbach, B; Marcus, K; Ramzan, R; Rhiel, A; Vogt, S; Wen, L | 1 |
| Eliceiri, BP; Levin, EG; Lin, AH | 1 |
| Dao-Feng, B; Wei, D; Xin-Long, C; Zhao-Fan, X | 1 |
| Aguado, E; Alonso, A; Aparicio, P; Domínguez-Villar, M; García-Blesa, A; García-Cózar, F; Malissen, B; Martínez-Florensa, M; Muñoz-Suano, A; Valdor, R; Yélamos, J | 1 |
| Li, M; Liu, Y; Lu, W; Na, B; Qin, H; Qing, G; Tang, M; Wang, D; Xiong, Y | 1 |
| Bento, I; Egri, P; Kirsch, K; Németh, K; Póti, ÁL; Reményi, A; Sok, P; Takács, T; Tusnády, GE; Zeke, A | 1 |
56 other study(ies) available for phosphotyrosine and serine
| Article | Year |
|---|---|
Signal transduction by the epidermal growth factor receptor is attenuated by a COOH-terminal domain serine phosphorylation site.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Serine; Signal Transduction; Substrate Specificity; Thymidine; Transfection; Tyrosine | 1992 |
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody.
Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
Determination of dityrosine, phosphotyrosine, phosphothreonine, and phosphoserine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Microchemistry; p-Dimethylaminoazobenzene; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Serine; Threonine; Tyrosine | 1990 |
[Phosphoamino acid analysis by 2-dimensional electrophoresis].
Topics: Electrophoresis, Gel, Two-Dimensional; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1990 |
PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.
Topics: Animals; Base Sequence; Cell Line; Hydrolysis; Isoenzymes; Molecular Sequence Data; Mutation; Peptides; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Serine; Transfection; Type C Phospholipases; Tyrosine | 1991 |
The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.
Topics: Animals; Antibodies, Monoclonal; Chick Embryo; Mutagenesis; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Sequence Homology, Nucleic Acid; Serine; Structure-Activity Relationship; Subcellular Fractions; Threonine; Tyrosine | 1991 |
Insulin-stimulated tyrosine phosphorylation of a 43 kDa protein in rat liver membranes.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Insulin; Membrane Proteins; Microsomes, Liver; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Restriction Mapping; Serine; Tyrosine | 1991 |
A simple and rapid method of quantitative analysis of phosphoamino acids by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1985 |
Characterization of the phosphotyrosyl protein phosphatase activity of calmodulin-dependent protein phosphatase.
Topics: Amino Acid Sequence; Animals; Brain; Calmodulin; Cattle; Fluorides; Kinetics; Manganese; Myocardium; Myosins; Nickel; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Serine; Tyrosine; Vanadates; Vanadium; Zinc | 1986 |
Resolution and identification of O-phosphoserine, O-phosphothreonine, O-phosphotyrosine, and gamma-carboxyglutamic acid as their fluorescent o-phthalaldehyde derivatives by high performance liquid chromatography.
Topics: 1-Carboxyglutamic Acid; Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; o-Phthalaldehyde; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1986 |
gp140v-fms molecules expressed at the surface of cells transformed by the McDonough strain of feline sarcoma virus are phosphorylated in tyrosine and serine.
Topics: Animals; Cats; Cell Transformation, Neoplastic; Genes; Genes, Viral; Oncogene Protein gp140(v-fms); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Retroviridae; Retroviridae Proteins; Serine; Tyrosine; Vanadates; Vanadium | 1986 |
Epidermal growth factor stimulates serine and tyrosine phosphorylation in a 59-kD protein in purified plasma membranes from rat liver.
Topics: Animals; Endopeptidases; Epidermal Growth Factor; Liver; Male; Membrane Proteins; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Inbred Strains; Serine; Serine Endopeptidases; Tyrosine | 1987 |
Determination of [32P]phosphoamino acids in protein hydrolysates by isocratic anion-exchange high-performance liquid chromatography.
Topics: Buffers; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Serine; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1988 |
Characterization of sites of serine phosphorylation in human placental insulin receptor copurified with insulin-stimulated serine kinase activity by two-dimensional thin-layer peptide mapping.
Topics: Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Insulin; Serine; Tyrosine | 1989 |
Serine and tyrosine phosphorylation of 28- and 35-kDa proteins of human T lymphocytes stimulated by streptococcal M protein.
Topics: Antigens, Bacterial; Antigens, Differentiation, T-Lymphocyte; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Humans; Lymphocyte Activation; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Phytohemagglutinins; Serine; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Tyrosine | 1989 |
Thin-layer chromatography can resolve phosphotyrosine, phosphoserine, and phosphothreonine in a protein hydrolyzate.
Topics: Animals; Autoradiography; Chromatography, Thin Layer; Humans; Hydrolysis; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1989 |
Antibodies and radioimmunoassays for phosphoserine, phosphothreonine and phosphotyrosine. Serologic specificities and levels of the phosphoamino acids in cytoplasmic fractions of rat tissues.
Topics: Animals; Antibodies; Antibody Specificity; Chromatography, Ion Exchange; Cytoplasm; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred F344; Serine; Serum Albumin, Bovine; Threonine; Tyrosine | 1989 |
Snyder-Theilen feline sarcoma virus P85 contains a single phosphotyrosine acceptor site recognized by its associated protein kinase.
Topics: Binding Sites; Cell Transformation, Neoplastic; Cell Transformation, Viral; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Retroviridae; Sarcoma Viruses, Feline; Serine; Tyrosine; Viral Proteins | 1981 |
Purified low-molecular-weight protein kinase from murine sarcoma virus particles catalyzes tyrosine phosphorylation endogenously but phosphorylates cellular proteins at serine.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Viral; Magnesium; Mice; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proteins; Sarcoma Viruses, Murine; Serine; Tyrosine | 1981 |
Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.
Topics: Amino Acids; Animals; Insulin; Liver Neoplasms, Experimental; Macromolecular Substances; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptor, Insulin; Serine; Tyrosine | 1982 |
Separation of phosphohydroxyamino acids by high-performance liquid chromatography.
Topics: Animals; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic AMP; Hydrolysis; Myelin Basic Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Serine; Threonine; Tyrosine | 1982 |
Two-dimensional separation of phosphoamino acids from nucleoside monophosphates.
Topics: Adenosine Monophosphate; Chromatography, Thin Layer; Cytidine Monophosphate; Electrophoresis; Escherichia coli; Guanosine Monophosphate; Nucleotides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Thymidine Monophosphate; Tyrosine; Uracil Nucleotides; Uridine Monophosphate | 1982 |
Dansylation and high-performance liquid chromatographic separation of phosphoserine, phosphothreonine and phosphotyrosine from 32P-labeled protein hydrolyzates.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Dansyl Compounds; Hydrolysis; In Vitro Techniques; Isotope Labeling; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Rats; Serine; Threonine; Tyrosine | 1982 |
A rapid microdetermination of phosphoserine, phosphothreonine, and phosphotyrosine in proteins by automatic cation exchange on a conventional amino acid analyzer.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Myocardium; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1983 |
Polyamide thin-layer chromatography of phosphorylated tyrosine, threonine, and serine.
Topics: Chromatography, Thin Layer; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1983 |
Measurement of chemical phosphate in proteins.
Topics: Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphotyrosine; Proteins; Radioisotope Dilution Technique; Serine; Tyrosine | 1983 |
Phosphorylation of tyrosine in cultured human placenta.
Topics: Culture Techniques; Female; Gestational Age; Humans; Phosphoproteins; Phosphorylation; Phosphotyrosine; Placenta; Pregnancy; Protein Kinases; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1984 |
Chemical properties, isolation, and analysis of O-phosphates in proteins.
Topics: Carbon Radioisotopes; Chemical Phenomena; Chemistry; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tritium; Tyrosine | 1984 |
GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Dogs; ErbB Receptors; Erythrocytes; G(M3) Ganglioside; Humans; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Tumor Cells, Cultured; Tyrosine | 1994 |
A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand.
Topics: Amino Acid Sequence; Animals; Base Sequence; Casein Kinases; Cell Line; Chromatography, Affinity; Cloning, Molecular; DNA, Complementary; Glutamic Acid; Humans; Ligands; Mice; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins pp60(c-src); RNA; Sequence Homology, Amino Acid; Serine; Tyrosine | 1994 |
Studies into the identity of the sites of insulin-stimulated insulin receptor serine phosphorylation. Characterization of synthetic peptide substrates for the insulin-stimulated insulin receptor serine kinase.
Topics: Amino Acid Sequence; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insulin; Molecular Sequence Data; Peptide Mapping; Phosphopeptides; Phosphoserine; Phosphotyrosine; Placenta; Pregnancy; Receptor, Insulin; Serine; Substrate Specificity; Trypsin; Tyrosine | 1995 |
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Chlorocebus aethiops; Conserved Sequence; DNA-Binding Proteins; Gene Expression Regulation; Humans; Luciferases; Mice; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine | 1995 |
Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Glutathione Transferase; GTPase-Activating Proteins; HeLa Cells; Homeostasis; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Fragments; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proteins; ras GTPase-Activating Proteins; Recombinant Fusion Proteins; Serine; src Homology Domains; src-Family Kinases; Transfection | 1995 |
Accumulation of unphosphorylated calponin in the submembranous cytoskeletons of arachidonic acid-stimulated human platelets.
Topics: Actins; Arachidonic Acid; Calcium-Binding Proteins; Calponins; Cytoskeletal Proteins; Humans; Microfilament Proteins; Microscopy, Fluorescence; Muscle Proteins; Phosphorylation; Phosphotyrosine; Platelet Activation; Protein Binding; Serine; Stimulation, Chemical; Threonine | 1996 |
Studies on an insulin-stimulated insulin receptor serine kinase activity: separation of the kinase activity from the insulin receptor and its reconstitution back to the insulin receptor.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glycogen Synthase Kinase 3; Humans; Insulin; Magnesium; Membrane Proteins; Microtubule-Associated Proteins; Myelin Basic Protein; Peptides; Phosphates; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Substrate Specificity | 1995 |
Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cell Line; Electrophoresis, Gel, Two-Dimensional; ErbB Receptors; GRB2 Adaptor Protein; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Mutagenesis; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Rabbits; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Threonine; Tyrosine | 1996 |
Small molecule interactions with protein-tyrosine phosphatase PTP1B and their use in inhibitor design.
Topics: Binding Sites; Calorimetry; Computer Simulation; Crystallography, X-Ray; Cysteine; Drug Design; Enzyme Inhibitors; Kinetics; Models, Molecular; Naphthalenes; Organophosphonates; Phosphotyrosine; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Recombinant Proteins; Serine | 1996 |
The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues.
Topics: Adenosine Triphosphate; Animals; Baculoviridae; Cloning, Molecular; Escherichia coli; Humans; Luciferases; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Serine; Spodoptera; Threonine; Transfection; Tyrosine | 1997 |
Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Cell Line; DNA Primers; Humans; Insulin Receptor Substrate Proteins; Kidney; Kinetics; Liver; Mice; Mice, Obese; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Protein Kinase C; Receptor, Insulin; Recombinant Proteins; Sequence Tagged Sites; Serine; Transfection; Tyrosine | 1997 |
Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Alanine; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Insulin; Insulin-Like Growth Factor I; Isoenzymes; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Transfection; Tyrosine | 1997 |
Phosphorylation of Tyr7, Tyr10, and Ser27 of alpha-chain in H+,K(+)-ATPase by intrinsic and extrinsic kinases.
Topics: Animals; Cholic Acids; Detergents; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Serine; Swine; Tyrosine | 1997 |
Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2. A study with peptide substrates derived from immunophilin Fpr3.
Topics: Amino Acid Sequence; Casein Kinase II; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Peptidylprolyl Isomerase; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine; Tyrosine | 1999 |
N-(cyclohexanecarboxyl)-O-phospho-l-serine, a minimal substrate for the dual-specificity protein phosphatase IphP.
Topics: Binding Sites; Cell Cycle Proteins; Cyanobacteria; Cyclohexanes; Dual Specificity Phosphatase 3; Humans; Hydrolysis; Isomerism; Kinetics; Molecular Weight; Multienzyme Complexes; Muramidase; Myelin Basic Protein; Naphthalenes; Organophosphorus Compounds; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity | 2000 |
Control of transfer RNA maturation by phosphorylation of the human La antigen on serine 366.
Topics: Autoantigens; Base Sequence; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Phosphorylation; Phosphotyrosine; Ribonucleoproteins; RNA Precursors; RNA, Transfer, Ser; Schizosaccharomyces; Serine; SS-B Antigen; Transcription Factors | 2000 |
Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3.
Topics: Animals; Cell Line; Cytokines; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; I-kappa B Proteins; Intracellular Fluid; Janus Kinase 1; Listeria monocytogenes; Macrophages; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Phosphotyrosine; Protein Biosynthesis; Protein-Tyrosine Kinases; Proteins; Repressor Proteins; Serine; Signal Transduction; STAT1 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Transcription Factors | 2001 |
Distinct functions of the two protein tyrosine phosphatase domains of LAR (leukocyte common antigen-related) on tyrosine dephosphorylation of insulin receptor.
Topics: Animals; Binding Sites; COS Cells; Cysteine; Gene Deletion; Immunoblotting; Immunosorbent Techniques; Insulin; Mutagenesis; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor, Insulin; Receptors, Cell Surface; Serine; Structure-Activity Relationship; Substrate Specificity; Transfection | 2001 |
O-phospho-L-tyrosine protects TP53 wild-type cells against ionizing radiation.
Topics: Blotting, Western; Cell Line, Transformed; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Complementary; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Mutation; Neoplasms; Phosphotyrosine; Radiation-Protective Agents; Serine; Threonine; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Fibroblast growth factor-2-induced signaling through lipid raft-associated fibroblast growth factor receptor substrate 2 (FRS2).
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Brain; Detergents; Enzyme Activation; Fibroblast Growth Factor 2; Humans; Lipid Metabolism; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Microdomains; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Octoxynol; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Serine; Signal Transduction; Threonine; Time Factors; Tumor Cells, Cultured; Tyrosine | 2003 |
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.
Topics: Biopsy; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hexokinase; Humans; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptor, Insulin; Reference Values; RNA, Messenger; Serine | 2003 |
Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance.
Topics: Adenoviridae; Animals; Binding Sites; Cell Line; Cricetinae; Enzyme Activation; Gene Expression Regulation, Viral; Genes, myc; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine | 2004 |
Phosphorylation and kinetics of mammalian cytochrome c oxidase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Cattle; Electron Transport Complex IV; Kinetics; Mitochondria, Heart; Myocardium; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2008 |
FAK mediates the inhibition of glioma cell migration by truncated 24 kDa FGF-2.
Topics: Cell Line, Tumor; Cell Movement; Fibroblast Growth Factor 2; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Glioma; Humans; Neovascularization, Pathologic; Phosphorylation; Phosphotyrosine; Serine; Tyrosine | 2009 |
mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.
Topics: Animals; Anti-Bacterial Agents; Blotting, Western; Burns; C-Peptide; Disease Models, Animal; Glucose Clamp Technique; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle, Skeletal; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Serine; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2011 |
Serine residues in the LAT adaptor are essential for TCR-dependent signal transduction.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Calcium; Cell Membrane; Conserved Sequence; Enzyme Activation; HEK293 Cells; Humans; Interleukin-2; Jurkat Cells; Membrane Proteins; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutant Proteins; Mutation; Phospholipase C gamma; Phosphoproteins; Phosphotyrosine; Protein Binding; Receptors, Antigen, T-Cell; Serine; Signal Transduction; Structure-Activity Relationship; Transfection; ZAP-70 Protein-Tyrosine Kinase | 2011 |
Discerning Tyrosine Phosphorylation from Multiple Phosphorylations Using a Nanofluidic Logic Platform.
Topics: Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Serine; Threonine; Tyrosine | 2021 |
Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Topics: CD28 Antigens; Insulin; Insulin Receptor Substrate Proteins; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Threonine | 2022 |