phosphotyrosine has been researched along with phosphothreonine in 193 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (16.06) | 18.7374 |
| 1990's | 105 (54.40) | 18.2507 |
| 2000's | 44 (22.80) | 29.6817 |
| 2010's | 12 (6.22) | 24.3611 |
| 2020's | 1 (0.52) | 2.80 |
| Authors | Studies |
|---|---|
| Gelman, MS; Hadcock, JR; Malbon, CC; Port, JD | 1 |
| Li, P; Roberts, TM; Williams, NG | 1 |
| Afar, DE; Bell, JC; Ben-David, Y; Douville, EM; Howell, BW; Letwin, K; Pawson, T; Tannock, L | 1 |
| Haystead, T; Hunt, DF; Michel, H; Rossomando, A; Shabanowitz, J; Sturgill, TW; Wu, J | 1 |
| Crews, CM; Erikson, RL | 1 |
| Pelech, SL; Sanghera, JS | 1 |
| Bird, TA; Saklatvala, J | 1 |
| Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P | 1 |
| Anderson, SR; Malencik, DA; Zhao, ZZ | 1 |
| Clinton, GM; Li, SW; Lin, YZ | 1 |
| Granot, Y; Schrier, RW; Van Putten, V | 1 |
| Ermel, B; Häring, HU; Kellerer, M; Obermaier-Kusser, B; Petrides, PE; Wallner, U | 1 |
| Cozzone, AJ; Dadssi, M | 1 |
| Iwashita, S; Mitsui, K | 1 |
| App, H; Baccarini, M; Rapp, UR; Sabatini, DM; Stanley, ER | 1 |
| Ballou, LM; Luther, H; Thomas, G | 1 |
| Marshall, SH; Muñoz, G | 1 |
| Meggio, F; Perich, JW; Pinna, LA; Reynolds, EC | 1 |
| Byun, SM; Kang, KR; Kang, YS; Kim, CW; Kim, YW | 1 |
| Friedmann, M; Hoover, D; Magnuson, NS; Reeves, R | 1 |
| Kataoka, H; Makita, M; Sakiyama, N | 1 |
| Iqbal, K; Murthy, LR | 1 |
| Cohen, P; Gómez, N | 1 |
| Ballotti, R; Filloux, C; Nguyen, TT; Scimeca, JC; Van Obberghen, E | 1 |
| Ringer, DP | 1 |
| Anderson, NG; Erickson, AK; Ray, LB; Sturgill, TW | 1 |
| Bennich, H; Craig, AG; Engström, A; Hoffmann-Posorske, E; Meyer, HE | 1 |
| Aitken, A; Morrice, N | 1 |
| Carlomagno, L; Huebner, VD; Matthews, HR | 1 |
| Londesborough, J | 1 |
| Bretscher, A; Cooper, JA; Gould, KL; Hunter, T | 1 |
| Ziemiecki, A | 1 |
| Bárány, K; Bárány, M; Csabina, S; Mougios, V | 1 |
| Bergeron, JJ; Kay, DG; Khan, MN; Lai, WH; Posner, BI; Uchihashi, M | 1 |
| Chinkers, M; Garbers, DL | 1 |
| Etheredge, RW; Glimcher, MJ | 1 |
| Niedbalski, JS; Ringer, DP | 1 |
| Destrée, OH; Sluyser, M | 1 |
| Rosen, OM | 1 |
| Kinsey, WH; Peaucellier, G; Veno, PA | 1 |
| Colca, JR; McCroskey, MC; Pearson, JD | 1 |
| Johnson, PJ; Kmiecik, TE; Shalloway, D | 1 |
| Eigenbrodt, E; Presek, P; Reinacher, M | 1 |
| Foster, R; Martin, GS; Thorner, J | 1 |
| Boland, D; Goren, HJ; Neufeld, E | 1 |
| Gjika, HB; Levine, L; Van Vunakis, H | 1 |
| Dass, C | 1 |
| Clinton, GM; Huang, AS | 1 |
| Fujitaki, JM; Smith, RA; Yang, JC | 1 |
| Cozzone, AJ; Manai, M | 1 |
| Congote, LF | 1 |
| Capony, JP; Demaille, JG | 1 |
| Chang, WC; Chou, CK; Lee, ML; Lee, SC | 1 |
| Fehlmann, M; Gazzano, H; Kowalski, A; Van Obberghen, E | 1 |
| Foulkes, JG | 1 |
| Dasgupta, JD; Garbers, DL; Swarup, G | 1 |
| Auricchio, F; Migliaccio, A; Rotondi, A | 1 |
| Martensen, TM | 1 |
| Baffet, G; Corcos, L | 1 |
| Fukunaga, R; Nagata, S; Pan, CX; Yonehara, S | 1 |
| Liu, WK; Yang, SD; Yen, SH; Yu, JS | 1 |
| Hakomori, S; Igarashi, Y; Kitamura, K; Zhou, Q | 1 |
| Berti, L; Häring, H; Kellerer, M; Kroder, G; Mosthaf, L; Mushack, J; Seedorf, K; Seffer, E; Tippmer, S | 1 |
| King, SM; Witman, GB | 1 |
| Izumi, T; Maller, JL | 1 |
| Anderson, MT; Gitler, C; Herzenberg, LA; Staal, FJ; Staal, GE | 1 |
| Daya-Makin, M; Hogg, JC; Lipp, M; Mogentale, TL; Parchomchuk, J; Pelech, SL; Sanghera, JS | 1 |
| DePaoli-Roach, AA; Fiol, CJ; Roach, PJ; Wang, QM | 1 |
| Damuni, Z; Li, M; Xiong, H | 1 |
| Benjamin, CW; Jones, DA; Linseman, DA | 1 |
| Ali, N; Chua, NH; Halfter, U | 1 |
| Bird, TA; Gayle, M; Kyriakis, JM; Milne, A; Tyshler, L; Virca, GD | 1 |
| Abu-Lawi, KI; Sultzer, BM | 1 |
| Hoffmann, R; Kalbitzer, HR; Reichert, I; Wachs, WO; Zeppezauer, M | 1 |
| Brinkmann, AO; Kuiper, GG | 1 |
| Marshall, SH; Muñoz, GE | 1 |
| Kinsey, WH | 1 |
| Giasson, E; Meloche, S | 1 |
| Adam, LP; Gunst, SJ; Pavalko, FM; Walker, TL; Wu, MF | 1 |
| Kumar, R | 1 |
| Butch, E; Guan, KL | 1 |
| Davis, RJ; Dickens, M; Gupta, S; Han, J; Raingeaud, J; Rogers, JS; Ulevitch, RJ | 1 |
| Pillay, I; Sharma, SV | 1 |
| Fujiki, N; Hamaguchi, M; Miyadai, T; Mutoh, T; Tokuda, A | 1 |
| Lacombe, JM; Mora, N; Pavia, AA | 1 |
| Benarous, R; Bodéus, M; Bougeret, C; Marie-Cardine, A; Ramos-Morales, F | 1 |
| Cuveele, JF; de Witte, PA; Merlevede, WJ; Vandenheede, JR | 1 |
| Cobb, MH; Ebert, D; Goldsmith, EJ; Zhang, F; Zhang, J | 1 |
| Maloy, S; Ostrovsky, PC | 1 |
| Biesinger, B; Desrosiers, RC; Friedrich, U; Jun, T; Jung, JU; Lang, SM; Roberts, TM | 1 |
| Parry, R; Sansom, D; Ward, S; Westwick, J; Wilson, A | 1 |
| Coleman, TR; Dunphy, WG; Kumagai, A; Mueller, PR | 1 |
| Lombardini, JB; Props, C | 1 |
| Bureau, MH; Laschet, JJ | 1 |
| Ploegh, HL; Schaap, D; van Blitterswijk, WJ; van der Bend, RL; van der Wal, J | 1 |
| Cleghon, V; Kaplan, DR; Rabin, SJ | 1 |
| Brewster, JL; de Valoir, T; Dwyer, ND; Gustin, MC; Winter, E | 1 |
| Inagami, T; Nakajo, S | 1 |
| Donella-Deana, A; Eisermann, B; Heber, M; Hoffmann-Posorske, E; Hutton, T; Korte, H; Meyer, HE; Perich, JW; Wegner, A; Weigt, C | 1 |
| Kataoka, H; Makita, M; Nakai, K | 1 |
| Egelhoff, TT; Lee, RJ; Spudich, JA | 1 |
| Abraham, I; McCroskey, MC; Sampson, KE | 1 |
| Elizarov, SM; Preobrazhensky, AA | 1 |
| Chen, L; Wu, L; Zhang, ZY | 1 |
| Kirschner, MW; Lee, TH | 1 |
| Denu, JM; Dixon, JE; Saper, MA; Yuvaniyama, J | 1 |
| Deyama, Y; Hisada, Y; Matsumoto, A; Okamoto, T; Suzuki, K; Yoshimura, Y | 1 |
| Goldstein, BJ; Li, PM | 1 |
| Appella, E; Roller, PP; Sakaguchi, K | 1 |
| Bennett, V; Hughes, CA; Matsuoka, Y | 1 |
| Agostinis, PM; Cuveele, JF; de Witte, PA; Merlevede, WJ | 1 |
| Borowski, P; Heiland, M; Kornetzky, L; Laufs, R; Roloff, S; Weber, W | 1 |
| Foltmann, B; Jensen, AL | 1 |
| Borgne, A; Meijer, L | 1 |
| Bianchi, R; Eichberg, J; Iyer, S; Rowe-Rendleman, CL | 1 |
| Eriksson, JW; Lönnroth, P; Smith, U; Wesslau, C | 1 |
| Göke, M; Kanai, M; Podolsky, DK; Tsunekawa, S | 1 |
| Ariatti, M; Hawtrey, AO; Van Jaarsveld, PP | 1 |
| Metzger, H; Pribluda, C; Pribluda, VS | 1 |
| Aitken, A; Learmonth, M | 1 |
| Bachvalova, VN; Maksimova, TG; Matveeva, VA; Morozova, OV; Tsekhanovskaya, NA | 1 |
| Ansotegui, IJ; Galron, D; Isakov, N | 1 |
| Olive, D; Parry, RV; Sansom, DM; Ward, SG; Westwick, J | 1 |
| Balaban, N; Goldkorn, T; Matsukuma, K; Shannon, M | 1 |
| Pawson, T; Scott, JD | 1 |
| Clark, JM; Gabrielli, BG | 1 |
| Cheatham, B; Emkey, R; Inoue, G; Kahn, CR | 1 |
| Gooley, AA; Packer, NH; Williams, KL; Yan, JX | 1 |
| Bracho, GE; Tash, JS | 1 |
| DeGnore, JP; Qin, J | 1 |
| Blom, N; Brunak, S; Kreegipuu, A | 1 |
| Chiang, TM | 1 |
| Godovac-Zimmermann, J; Müller-Esterl, W; Nyakatura, E; Roos, M; Soskic, V | 1 |
| Hamano, T; Yamaguchi, M | 1 |
| Nguyen, AN; Shiozaki, K | 1 |
| Duclos, B; Grangeasse, C; Riberty, M; Vaganay, E | 1 |
| Junttila, I; Kovanen, PE; Li, W; Saharinen, P; Silvennoinen, O; Takaluoma, K; Valmu, L | 1 |
| Brancho, DM; Davis, RJ; Enslen, H | 1 |
| Cheung, L; Ilan, N; Madri, JA; Pinter, E | 1 |
| Mattison, CP; Ota, IM | 1 |
| Corson, MA; Gallis, B; Kim, F | 1 |
| Cha, H; Shapiro, P | 1 |
| Cantley, LG; Liu, ZX; Roshan, B; Yu, CF | 1 |
| Danilenko, VN; Elizarov, SM | 1 |
| Bianchetti, R; Malerba, M | 1 |
| Bennett, KL; Jensen, ON; Moniatte, M; Podtelejnikov, AV; Stensballe, A | 1 |
| Luo, Z; Ruderman, N; Song, Y; Wen, R; Xiang, X; Yuan, M | 1 |
| Castagnoli, L; Cesareni, G; Nardelli, G; Panni, S | 1 |
| Imperiali, B; Rothman, DM; Vázquez, ME; Vogel, EM | 1 |
| Schmitt, JM; Stork, PJ | 1 |
| Frost, A; Hawes, J; Lamothe, B; Lax, I; Lee, A; Schlessinger, J; Wong, A | 1 |
| Frank, SJ; Huang, Y; Jiang, J; Kim, SO | 1 |
| Assfeld, X; Cartier, A; Ganicz, K; Gardiennet, C; Olejniczak, S; Potrzebowski, MJ; Tekely, P | 1 |
| Haystead, TA; Mackey, AJ; Pearson, WR | 1 |
| Jackson, JL; Young, MR | 1 |
| Boël, G; Decottignies, P; Deutscher, J; Doublet, P; Gillet, S; Grangeasse, C; Jamet, E; Le Maréchal, P; Mazé, A; Mijakovic, I; Poncet, S | 1 |
| Gu, S; Ji, C; Li, D; Li, N; Li, Y; Mao, Y; Wu, Q; Xie, Y; Zheng, D; Zheng, Z | 1 |
| Fukaya, Y; Yamaguchi, M | 1 |
| Aggeler, R; Capaldi, RA; Goodman, TN; Patton, WF; Schulenberg, B | 1 |
| Antrobus, R; Botting, CH; Coote, PJ; Makrantoni, V | 1 |
| Aust, AE; Baldys, A; Mosleh, T; Pande, P; Park, SH | 1 |
| Costanzo, V; D'Angiolella, V; Grieco, D; Palazzo, L; Santarpia, C | 1 |
| Barker, DL; Hachmann, JP; Kermani, BG; Kozlov, IA; Lebl, M; Melnyk, PC; Musmacker, J; Nelson, N; Shevchenko, V; Shults, MD; Srinivasan, A; Zhao, C | 1 |
| Casas, E; Francis, SA; Lynch, RD; McCarthy, KM; Schneeberger, EE; Thiele, C | 1 |
| Cozzone, AJ; Duclos, B; Grangeasse, C; Soulat, D; Vaganay, E | 1 |
| Lim, KM; Tan, VB; Tay, TE; Zhang, B | 1 |
| Gao, YY; Li, H; Li, QF; Liu, R; Peng, XX; Wang, SY; Zhang, DF; Zhuang, ZH | 1 |
| Camp, DG; Kim, J; Moore, RJ; Petritis, K; Shen, Y; Smith, RD | 1 |
| Chica, C; Diella, F; Gibson, TJ; Gould, CM; Via, A | 1 |
| Chen, S; Hu, L; Li, H; Liu, L; Long, C; Shao, F; Wang, DC; Xu, H; Zhu, Y | 1 |
| Barbato, G; De Francesco, R; Forte, E; Orsatti, L; Talamo, F; Tomei, L | 1 |
| Du, JY; Hsin, CH; Hsu, TC; Huang, CH; Lee, CF; Lee, YJ; Lin, TH; Wu, WJ; Yao, TY | 1 |
| Sefton, BM | 1 |
| Daudi, A; Ishihama, Y; Mochida, K; Nakagami, H; Shirasu, K; Sugiyama, N; Tomita, M | 1 |
| Angulo, DS; Kristjansdottir, K; Kron, SJ; Lucius, N; Wolfgeher, D | 1 |
| Helling, S; Kadenbach, B; Marcus, K; Ramzan, R; Rhiel, A; Vogt, S; Wen, L | 1 |
| Jackson, SN; Moyer, SC; Woods, AS | 1 |
| Frank, SJ; Huang, Y; Jiang, J; Li, X | 1 |
| Bui, L; Konradsson, P; Magnusson, KE; Vikström, E | 1 |
| Pocsfalvi, G | 1 |
| Buckley, DA; Lindsay, AJ; McCaffrey, MW; Neubert, TA; Schwertassek, U; Tonks, NK; Xu, CF | 1 |
| Barone, E; Butterfield, DA; Cenini, G; Cini, C; Di Domenico, F; Mancuso, C; Perluigi, M; Preziosi, P; Sultana, R | 1 |
| Kim, BG; Kim, J; Kim, M; Lee, YS; Park, YS; Shin, DS | 1 |
| Neubert, TA; Zhang, G | 1 |
| de Widt, J; Divecha, N; van Baal, J; van Blitterswijk, WJ | 1 |
| Chafe, SC; Mangroo, D; Pierce, JB | 1 |
| Chang, SF; Chen, LJ; Chien, S; Chiu, JJ; Lee, DY; Lee, PL | 1 |
| Chien, PN; Hwang, HS; Jeon, TJ; Jeong, DG; Kim, DS; Kim, JK; Kim, SJ; Ku, B; Park, H; Park, SY; Ryu, SE; Ryu, SY; Wei, CH | 1 |
| Aerni, HR; Liu, Y; Rinehart, J; Rogulina, S; Steinfeld, JB | 1 |
| Castranova, V; Cruz-Silva, R; Ding, W; Endo, M; McLoughlin, C; Mihalchik, AL; Porter, DW; Qian, Y; Schwegler-Berry, D; Sisler, JD; Snyder-Talkington, BN; Stefaniak, AB; Terrones, M; Tsuruoka, S | 1 |
| Cherry, S; Gumpena, R; Lountos, GT; Raran-Kurussi, S; Tropea, JE; Waugh, DS | 1 |
| Boccellato, F; Briza, P; Chichirau, BE; Engler, D; Gadermaier, G; Hauser-Kronberger, C; Krisch, LM; Meyer, TF; Müller, A; Neureiter, D; Posselt, G; Schneider, S; Wessler, S; Wiesauer, M | 1 |
| Bőhmová, M; Gybeľ, T; Pacherník, J; Radaszkiewicz, KA; Radaszkiewicz, TW; Sladeček, S | 1 |
6 review(s) available for phosphotyrosine and phosphothreonine
| Article | Year |
|---|---|
After insulin binds.
Topics: DNA; Drosophila; ErbB Receptors; Humans; Insulin; Molecular Weight; Oncogenes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Cell Surface; Substrate Specificity; Tyrosine | 1987 |
Phosphotyrosyl-protein phosphatases.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Cell Transformation, Viral; Oncogenes; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Retroviridae; Tyrosine | 1983 |
Strategies for nonradioactive methods in the localization of phosphorylated amino acids in proteins.
Topics: Amino Acid Sequence; Amino Acids; Mass Spectrometry; Molecular Sequence Data; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1993 |
Chemical synthesis and applications of phosphopeptides.
Topics: Amino Acid Sequence; Animals; Antibodies; Antigens; Models, Molecular; Molecular Sequence Data; Organophosphonates; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Structure, Secondary; src Homology Domains; Substrate Specificity; Thermodynamics | 1996 |
Signaling through scaffold, anchoring, and adaptor proteins.
Topics: Amino Acid Sequence; Animals; Ligands; Phospholipids; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Signal Transduction; src Homology Domains | 1997 |
Protein phosphorylation: technologies for the identification of phosphoamino acids.
Topics: Animals; Humans; Phosphoamino Acids; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1998 |
187 other study(ies) available for phosphotyrosine and phosphothreonine
| Article | Year |
|---|---|
Cross-talk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of beta 2-adrenergic receptors in response to insulin.
Topics: Animals; Cell Line; Cricetinae; GTP-Binding Proteins; Insulin; Iodine Radioisotopes; Isoproterenol; Kinetics; Male; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Adrenergic, beta; Tyrosine; Vas Deferens | 1992 |
Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase.
Topics: Animals; Cells, Cultured; Enzyme Activation; In Vitro Techniques; Moths; Oncogene Protein pp60(v-src); Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Tyrosine | 1992 |
Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Compartmentation; Cell Membrane; Cloning, Molecular; Cytoplasm; DNA; Gene Expression; In Vitro Techniques; Mice; Molecular Sequence Data; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; RNA, Messenger; Sequence Alignment; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1992 |
Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal muscle.
Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, Gel; Female; Mass Spectrometry; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Molecular Weight; Muscles; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Denaturation; Protein Kinases; Rabbits; Sequence Homology, Nucleic Acid; Tyrosine | 1992 |
Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product.
Topics: Amino Acid Sequence; Animals; Enzyme Activation; Fungal Proteins; Genes; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Recombinant Proteins; Sequence Alignment; Tyrosine | 1992 |
MAP kinases: charting the regulatory pathways.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Homeostasis; Humans; Myelin Basic Protein; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1992 |
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 1990 |
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody.
Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
Determination of dityrosine, phosphotyrosine, phosphothreonine, and phosphoserine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Microchemistry; p-Dimethylaminoazobenzene; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Serine; Threonine; Tyrosine | 1990 |
Insulin and epidermal growth factor stimulate phosphorylation of p185HER-2 in the breast carcinoma cell line, BT474.
Topics: Blood; Breast Neoplasms; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, ErbB-2; Tumor Cells, Cultured; Tyrosine | 1990 |
Vasopressin dependent tyrosine phosphorylation of a 38 kDa protein in human platelets.
Topics: Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Platelets; Blotting, Western; Colforsin; Dose-Response Relationship, Drug; Electrophoresis; Humans; In Vitro Techniques; Phorbol Esters; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Vasopressin; Time Factors; Tyrosine | 1990 |
An altered IGF-I receptor is present in human leukemic cells.
Topics: Cell Division; Cell Membrane; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Fetus; Genetic Variation; Glycosylation; Humans; Insulin; Insulin-Like Growth Factor I; Leukemia, Promyelocytic, Acute; Molecular Weight; Peptide Mapping; Phosphorylation; Phosphothreonine; Phosphotyrosine; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins; Trypsin; Tumor Cells, Cultured; Tyrosine | 1990 |
Occurrence of protein phosphorylation in various bacterial species.
Topics: Adenosine Triphosphate; Arthrobacter; Bacillus; Bacillus megaterium; Bacteria; Bacterial Proteins; Cyclic AMP; Cyclic GMP; Escherichia coli; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Pseudomonas; Tyrosine | 1990 |
[Phosphoamino acid analysis by 2-dimensional electrophoresis].
Topics: Electrophoresis, Gel, Two-Dimensional; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1990 |
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product.
Topics: Amino Acid Sequence; Animals; In Vitro Techniques; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Molecular Sequence Data; Oligopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptor, Macrophage Colony-Stimulating Factor; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Temperature; Tyrosine | 1990 |
MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways.
Topics: Adipose Tissue; Animals; Blood; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Reactivators; Epidermal Growth Factor; Fibroblasts; Insulin; Mice; Oocytes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Tyrosine; Xenopus | 1991 |
An alternative method for a fast separation of phosphotyrosine.
Topics: Adenosine Triphosphate; Animals; Chromatography, Thin Layer; Cytidine Monophosphate; Humans; Liver; Lymphocytes; Mice; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine; Uridine Monophosphate | 1990 |
Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase.
Topics: Amino Acid Sequence; Animals; Casein Kinases; Cell Division; Cytosol; Kinetics; Liver; Molecular Sequence Data; Oligopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Substrate Specificity; Tyrosine | 1991 |
Elongation factor-2 in chick embryo is phosphorylated on tyrosine as well as serine and threonine.
Topics: Age Factors; Animals; Chick Embryo; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Subcellular Fractions; Tyrosine | 1991 |
Recombinant human pim-1 protein exhibits serine/threonine kinase activity.
Topics: Cloning, Molecular; DNA; Escherichia coli; Humans; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Recombinant Proteins; Substrate Specificity; Tyrosine | 1991 |
Distribution and contents of free O-phosphoamino acids in animal tissues.
Topics: Animals; Brain Chemistry; Chickens; Chromatography, Gas; Fishes; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Myocardium; Organ Specificity; Phosphoserine; Phosphothreonine; Phosphotyrosine; Species Specificity; Swine; Tyrosine | 1991 |
Measurement of picomoles of phosphoamino acids by high-performance liquid chromatography.
Topics: Amino Acids; Caseins; Chromatography, High Pressure Liquid; Organophosphorus Compounds; Phosphoserine; Phosphothreonine; Phosphotyrosine; Reproducibility of Results; Serum Albumin, Bovine; Tyrosine | 1991 |
Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Antigens, CD; Enzyme Activation; Histocompatibility Antigens; In Vitro Techniques; Leukocyte Common Antigens; Nerve Growth Factors; Neurons; Pheochromocytoma; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Rats; Receptor, trkA; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1991 |
Tyrosine and threonine phosphorylation of an immunoaffinity-purified 44-kDa MAP kinase.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Fibroblasts; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Molecular Weight; Myelin Basic Protein; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1991 |
Separation of phosphotyrosine, phosphoserine, and phosphothreonine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1991 |
Purification of mitogen-activated protein kinase from epidermal growth factor-treated 3T3-L1 fibroblasts.
Topics: 3T3 Cells; Animals; Autoradiography; Buffers; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Indicators and Reagents; Kinetics; Mice; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1991 |
Plasma desorption mass spectrometry of phosphopeptides: an investigation to determine the feasibility of quantifying the degree of phosphorylation.
Topics: Amino Acid Sequence; Mass Spectrometry; Molecular Sequence Data; Oligopeptides; Phosphopeptides; Phosphorylation; Phosphothreonine; Phosphotyrosine; Tyrosine | 1991 |
A simple and rapid method of quantitative analysis of phosphoamino acids by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1985 |
Rapid separation of phosphoamino acids including the phosphohistidines by isocratic high-performance liquid chromatography of the orthophthalaldehyde derivatives.
Topics: Aldehydes; Amino Acids; Arginine; Buffers; Chromatography, High Pressure Liquid; Histidine; o-Phthalaldehyde; Organophosphorus Compounds; Phosphoserine; Phosphothreonine; Phosphotyrosine; Temperature; Tyrosine | 1985 |
Phosphorylation of proteins in Clostridium thermohydrosulfuricum.
Topics: Bacterial Proteins; Calmodulin; Cell-Free System; Clostridium; Hexosephosphates; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyamines; Subcellular Fractions; Tyrosine | 1986 |
The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.
Topics: Animals; Carrier Proteins; Cell Line; Cytoskeletal Proteins; Fluorescent Antibody Technique; Humans; Isoelectric Point; Microfilament Proteins; Microvilli; Molecular Weight; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Subcellular Fractions; Tissue Distribution; Tyrosine | 1986 |
Characterization of the monomeric and complex-associated forms of the gag-onc fusion proteins of three isolates of feline sarcoma virus: phosphorylation, kinase activity, acylation, and kinetics of complex formation.
Topics: Acylation; Animals; Cats; Cells, Cultured; Fibroblasts; Gene Products, gag; Kinetics; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae; Retroviridae Proteins; Sarcoma Viruses, Feline; Tyrosine | 1986 |
Characterization of the phosphorylatable myosin light chain in rat uterus.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Female; Isoelectric Point; Molecular Weight; Myosins; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Tyrosine; Uterus | 1986 |
Epidermal growth factor receptor kinase translocation and activation in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Golgi Apparatus; Kinetics; Liver; Male; Microscopy, Electron; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Tyrosine | 1986 |
Regulation of the phosphorylation state and function of the epidermal growth factor receptor by vitamin K-3.
Topics: Calcium; Cells, Cultured; ErbB Receptors; Humans; Phosphoproteins; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tyrosine; Vitamin K | 1986 |
Resolution and identification of O-phosphoserine, O-phosphothreonine, O-phosphotyrosine, and gamma-carboxyglutamic acid as their fluorescent o-phthalaldehyde derivatives by high performance liquid chromatography.
Topics: 1-Carboxyglutamic Acid; Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; o-Phthalaldehyde; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1986 |
Separation and quantitative analysis of O-linked phosphoamino acids by isocratic high-performance liquid chromatography of the 9-fluorenylmethyl chloroformate derivatives.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Fluorenes; Ion Exchange Resins; Organophosphorus Compounds; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1986 |
Histone phosphorylation in explants of mouse mammary glands and tumors.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Histones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1986 |
Protein tyrosine phosphorylation in response to fertilization.
Topics: Adenosine Triphosphate; Animals; Centrifugation, Density Gradient; Egg Proteins; Electrophoresis, Polyacrylamide Gel; Female; Fertilization; Immunoassay; Immunosorbent Techniques; Molecular Weight; Ovum; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Sea Urchins; Tyrosine | 1988 |
Determination of [32P]phosphoamino acids in protein hydrolysates by isocratic anion-exchange high-performance liquid chromatography.
Topics: Buffers; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Serine; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1988 |
Regulation by the autophosphorylation site in overexpressed pp60c-src.
Topics: Animals; Mice; Mutation; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Structure-Activity Relationship; Tyrosine; Vanadium | 1988 |
Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Immunosorbent Techniques; Kinetics; Oncogene Protein pp60(v-src); Phosphoenolpyruvate; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Pyruvate Kinase; Retroviridae Proteins; Tyrosine | 1988 |
Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria.
Topics: Electrophoresis, Gel, Two-Dimensional; Escherichia coli; Glutamate-Ammonia Ligase; Hydrolysis; Molecular Weight; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Radioisotope Dilution Technique; Salmonella typhimurium; Species Specificity; Tyrosine | 1989 |
Thin-layer chromatography can resolve phosphotyrosine, phosphoserine, and phosphothreonine in a protein hydrolyzate.
Topics: Animals; Autoradiography; Chromatography, Thin Layer; Humans; Hydrolysis; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1989 |
Antibodies and radioimmunoassays for phosphoserine, phosphothreonine and phosphotyrosine. Serologic specificities and levels of the phosphoamino acids in cytoplasmic fractions of rat tissues.
Topics: Animals; Antibodies; Antibody Specificity; Chromatography, Ion Exchange; Cytoplasm; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred F344; Serine; Serum Albumin, Bovine; Threonine; Tyrosine | 1989 |
Characterization of phosphorylated amino acids by fast-atom bombardment mass spectrometry.
Topics: Phosphoserine; Phosphothreonine; Phosphotyrosine; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1989 |
Distribution of phosphoserine, phosphothreonine and phosphotyrosine in proteins of vesicular stomatitis virus.
Topics: Animals; Cells, Cultured; Cricetinae; Kidney; Mesocricetus; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Tyrosine; Vesicular stomatitis Indiana virus; Viral Proteins | 1981 |
Separation of phosphohydroxyamino acids by high-performance liquid chromatography.
Topics: Animals; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic AMP; Hydrolysis; Myelin Basic Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Serine; Threonine; Tyrosine | 1982 |
Two-dimensional separation of phosphoamino acids from nucleoside monophosphates.
Topics: Adenosine Monophosphate; Chromatography, Thin Layer; Cytidine Monophosphate; Electrophoresis; Escherichia coli; Guanosine Monophosphate; Nucleotides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Thymidine Monophosphate; Tyrosine; Uracil Nucleotides; Uridine Monophosphate | 1982 |
Dansylation and high-performance liquid chromatographic separation of phosphoserine, phosphothreonine and phosphotyrosine from 32P-labeled protein hydrolyzates.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Dansyl Compounds; Hydrolysis; In Vitro Techniques; Isotope Labeling; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Rats; Serine; Threonine; Tyrosine | 1982 |
A rapid microdetermination of phosphoserine, phosphothreonine, and phosphotyrosine in proteins by automatic cation exchange on a conventional amino acid analyzer.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Myocardium; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1983 |
Polyamide thin-layer chromatography of phosphorylated tyrosine, threonine, and serine.
Topics: Chromatography, Thin Layer; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1983 |
Two different protein kinase activities are associated with the insulin receptor.
Topics: Animals; Caseins; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Histones; In Vitro Techniques; Isoenzymes; Liver; Male; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine | 1983 |
Tyrosine protein kinase activity in normal rat tissues: brain.
Topics: Animals; Binding Sites; Brain; Cations, Divalent; Male; Nerve Tissue Proteins; Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Rats; Structure-Activity Relationship; Tyrosine | 1984 |
Calmodulin-stimulated phosphorylation of 17 beta-estradiol receptor on tyrosine.
Topics: Animals; Calmodulin; Cattle; Cell Nucleus; Cytosol; Enzyme Activation; Estradiol; Female; Kinetics; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Receptors, Estradiol; Receptors, Estrogen; Tyrosine; Uterus | 1984 |
Chemical properties, isolation, and analysis of O-phosphates in proteins.
Topics: Carbon Radioisotopes; Chemical Phenomena; Chemistry; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tritium; Tyrosine | 1984 |
The liver-specific response to phenobarbital involves a transient increase in phosphorylation of a 34-kda nuclear protein in rat liver and in hepatocytes in culture.
Topics: Adenosine Triphosphate; Animals; Aryl Hydrocarbon Hydroxylases; Blood; Cells, Cultured; Culture Media; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Liver; Male; Molecular Weight; Nuclear Proteins; Phenobarbital; Phosphoproteins; Phosphorylation; Phosphothreonine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid Hydroxylases | 1995 |
Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptors.
Topics: Amino Acids; Animals; Cell Differentiation; Cell Division; Cell Line; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Macromolecular Substances; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptor Protein-Tyrosine Kinases; Receptors, Granulocyte Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Proteins; Transfection; Tyrosine | 1993 |
Synergistic control mechanism for abnormal site phosphorylation of Alzheimer's diseased brain tau by kinase FA/GSK-3 alpha.
Topics: Alzheimer Disease; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Glycogen Synthase Kinase 3; Humans; Kinetics; Microtubule-Associated Proteins; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Substrate Specificity; tau Proteins; Tyrosine | 1993 |
GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Dogs; ErbB Receptors; Erythrocytes; G(M3) Ganglioside; Humans; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Tumor Cells, Cultured; Tyrosine | 1994 |
Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase.
Topics: 3-O-Methylglucose; Animals; Cell Line; Fibroblasts; Glucose; Humans; Insulin; Isoenzymes; Kinetics; Mannitol; Methylglucosides; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Rats; Receptor, Insulin; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1994 |
Multiple sites of phosphorylation within the alpha heavy chain of Chlamydomonas outer arm dynein.
Topics: Animals; Centrifugation, Density Gradient; Chlamydomonas; Dyneins; Flagella; Pancreatic Elastase; Peptide Fragments; Phosphates; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Trypsin; Tyrosine | 1994 |
Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase.
Topics: Amino Acid Sequence; Animals; Base Sequence; CDC2 Protein Kinase; cdc25 Phosphatases; Cell-Free System; Consensus Sequence; Cyclins; Egg Proteins; Enzyme Activation; Fungal Proteins; Humans; Interphase; Mitosis; Molecular Sequence Data; Oocytes; Phosphoprotein Phosphatases; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tyrosine; Xenopus | 1993 |
Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx.
Topics: Aluminum Compounds; Calcium; CD3 Complex; Cell Line; Cytokines; Fluorides; Glutathione; Humans; In Vitro Techniques; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Terpenes; Thapsigargin; Tyrosine | 1994 |
Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung.
Topics: Adenocarcinoma; Amino Acid Sequence; Antibodies; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Casein Kinases; Caseins; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Kinetics; Lung; Lung Neoplasms; Molecular Sequence Data; Myelin Basic Protein; Peptides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Proteins; Substrate Specificity; Tyrosine | 1994 |
Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycogen Synthase Kinases; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Weight; Muscles; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Recombinant Proteins; Tyrosine | 1994 |
Autophosphorylation-activated protein kinase inactivates the protein tyrosine phosphatase activity of protein phosphatase 2A.
Topics: Adenosine Triphosphate; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; ErbB Receptors; Glycogen Synthase Kinase 3; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protamine Kinase; Protein Kinases; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Recombinant Proteins; Substrate Specificity; Tyrosine | 1994 |
Platelet-derived growth factor stimulates phosphorylation of growth factor receptor-binding protein-2 in vascular smooth muscle cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cells, Cultured; ErbB Receptors; GRB2 Adaptor Protein; In Vitro Techniques; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; Rats; Signal Transduction; Tyrosine | 1994 |
Cloning and biochemical characterization of a plant protein kinase that phosphorylates serine, threonine, and tyrosine.
Topics: Arabidopsis; Arabidopsis Proteins; Base Sequence; Cloning, Molecular; DNA Primers; Molecular Sequence Data; Phosphoserine; Phosphothreonine; Phosphotyrosine; Plant Proteins; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 1994 |
Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21ras, Raf-1, and MAP kinase kinase.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Ceramides; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Gingiva; Humans; In Vitro Techniques; Interleukin-1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphothreonine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Signal Transduction; Sphingosine; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1994 |
Induction of serine and threonine protein phosphorylation by endotoxin-associated protein in murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Bacterial Proteins; Dinoprostone; Endotoxins; Female; Ionomycin; Lipid A; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
1H and 31P NMR spectroscopy of phosphorylated model peptides.
Topics: Amino Acid Sequence; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Phosphopeptides; Phosphorus; Phosphoserine; Phosphothreonine; Phosphotyrosine; Structure-Activity Relationship; Tyrosine | 1994 |
Phosphotryptic peptide analysis of the human androgen receptor: detection of a hormone-induced phosphopeptide.
Topics: Androgens; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Metribolone; Molecular Weight; Peptide Mapping; Phosphates; Phosphoproteins; Phosphorylation; Phosphothreonine; Phosphotyrosine; Receptors, Androgen; Trypsin; Tumor Cells, Cultured; Tyrosine | 1995 |
Selective phosphoamino acid enrichment by organic solvent fractionation.
Topics: Acetone; Chemical Fractionation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1994 |
Differential phosphorylation of a 57-KDa protein tyrosine kinase during egg activation.
Topics: Amino Acid Sequence; Animals; Antibodies; Cell Cycle; Electrophoresis, Polyacrylamide Gel; Female; Fertilization; Genes, src; Male; Molecular Sequence Data; Molecular Weight; Oocytes; Peptides; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Sea Urchins; Spermatozoa; Tyrosine | 1995 |
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine | 1995 |
Phosphorylation of dense-plaque proteins talin and paxillin during tracheal smooth muscle contraction.
Topics: Acetylcholine; Animals; Binding Sites; Cytoskeletal Proteins; Dogs; Immunosorbent Techniques; Muscle Contraction; Muscle, Smooth; Paxillin; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Talin; Trachea; Tyrosine; Vinculin | 1995 |
Dual modulation of phosphorylation of a 60 kDa nuclear protein in interferon-alpha treated Daudi cells.
Topics: B-Lymphocytes; Cell Line; Humans; Interferon alpha-2; Interferon-alpha; Molecular Weight; Nuclear Proteins; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tyrosine | 1995 |
Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Dual-Specificity Phosphatases; Female; HeLa Cells; Humans; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Phosphatases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphothreonine; Phosphotyrosine; Placenta; Pregnancy; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; Substrate Specificity; Transfection; Tyrosine | 1995 |
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chlorocebus aethiops; Enzyme Activation; HeLa Cells; Humans; Inflammation; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Weight; Osmolar Concentration; Phosphorylation; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Sequence Deletion; Stress, Physiological; Subcellular Fractions; Substrate Specificity; Threonine; Transfection; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
In vivo and in vitro serine/threonine phosphorylations of epidermal growth factor receptor upon entry into the cell cycle.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Culture Media, Serum-Free; Electrophoresis, Gel, Two-Dimensional; ErbB Receptors; Flow Cytometry; Glioblastoma; Humans; Interphase; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; S Phase; Tyrosine | 1995 |
Ganglioside GM1 binds to the Trk protein and regulates receptor function.
Topics: Animals; Cell Differentiation; G(M1) Ganglioside; Kinetics; Nerve Growth Factors; Neurites; Neurofilament Proteins; PC12 Cells; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Tyrosine | 1995 |
A new approach to phosphoserine, phosphothreonine and phosphotyrosine synthons and to thiophospho analogs. Stepwise synthesis of mono- and multiphosphorylated phosphopeptides related to src-protein kinase.
Topics: Amino Acid Sequence; CSK Tyrosine-Protein Kinase; Molecular Sequence Data; Organothiophosphates; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine | 1995 |
In vitro binding and phosphorylation of human immunodeficiency virus type 1 Nef protein by serine/threonine protein kinase.
Topics: Base Sequence; Binding Sites; Cell Line; DNA Primers; Gene Products, nef; Genes, nef; Glutathione Transferase; HIV-1; Humans; Kinetics; Molecular Sequence Data; nef Gene Products, Human Immunodeficiency Virus; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Sequence Deletion; Tyrosine | 1995 |
Analysis of phosphorylhydroxyamino acids present in hydrolyzed cell extracts using dabsyl derivatization.
Topics: Cell Extracts; Chromatography, Thin Layer; Electrophoresis; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; p-Dimethylaminoazobenzene; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Protein-Tyrosine Kinases; Quercetin; Tumor Cells, Cultured; Tyrosine | 1995 |
Activity of the MAP kinase ERK2 is controlled by a flexible surface loop.
Topics: Amino Acid Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Crystallization; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine; Mitogen-Activated Protein Kinase 1; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Serine-Threonine Kinases; Structure-Activity Relationship; Tyrosine | 1995 |
Protein phosphorylation on serine, threonine, and tyrosine residues modulates membrane-protein interactions and transcriptional regulation in Salmonella typhimurium.
Topics: Adenosine Triphosphate; Bacterial Proteins; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Bacterial; Magnetic Resonance Spectroscopy; Membrane Proteins; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Kinases; Protein-Tyrosine Kinases; Salmonella typhimurium; Tyrosine | 1995 |
Identification of Lck-binding elements in tip of herpesvirus saimiri.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Chlorocebus aethiops; DNA Primers; Herpesvirus 2, Saimiriine; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Point Mutation; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Spodoptera; Structure-Activity Relationship; Transfection; Tyrosine; Viral Proteins | 1995 |
The phosphoinositide 3-kinase inhibitor wortmannin inhibits CD28-mediated T cell co-stimulation.
Topics: Androstadienes; Animals; CD28 Antigens; Cell Line; CHO Cells; Cricetinae; Enzyme Inhibitors; Humans; Lymphocyte Activation; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; T-Lymphocytes; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1995 |
Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.
Topics: Amino Acid Sequence; Animals; Base Sequence; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Membrane; Cloning, Molecular; Cyclins; Interphase; Mitosis; Molecular Sequence Data; Mutation; Nuclear Proteins; Oocytes; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Xenopus; Xenopus Proteins | 1995 |
Effects of cooling temperature on the separation of phosphoamino acids.
Topics: Cold Temperature; Electrophoresis; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1995 |
Endogenous phosphorylation of distinct gamma-aminobutyric acid type A receptor polypeptides by Ser/Thr and Tyr kinase activities associated with the purified receptor.
Topics: Affinity Labels; Animals; Blotting, Western; Cattle; Cell Membrane; Cerebral Cortex; Kinetics; Macromolecular Substances; Muscimol; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, GABA-A; Substrate Specificity; Thermodynamics | 1995 |
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Colforsin; Diacylglycerol Kinase; Epidermal Growth Factor; Epitopes; ErbB Receptors; Escherichia coli; Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1993 |
SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells.
Topics: Animals; Cell Differentiation; Mitogens; Nerve Growth Factors; Neurons; Nuclear Proteins; Oncogene Protein pp60(v-src); Oncogenes; PC12 Cells; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Tyrosine | 1993 |
An osmosensing signal transduction pathway in yeast.
Topics: Amino Acid Sequence; Blotting, Northern; Calcium-Calmodulin-Dependent Protein Kinases; Genes, Fungal; Molecular Sequence Data; Osmolar Concentration; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Kinases; Restriction Mapping; Saccharomyces cerevisiae; Signal Transduction; Tyrosine; Water-Electrolyte Balance | 1993 |
Atrial natriuretic factor stimulates phosphorylation of a 52-kDa calmodulin-binding protein in vascular smooth muscle cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Calmodulin-Binding Proteins; Cells, Cultured; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Endothelins; Male; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Rats, Wistar; Tyrosine | 1993 |
Identification of O-phosphoamino acids in urine hydrolysate by gas chromatography-mass spectrometry.
Topics: Amino Acids; Chromatography, DEAE-Cellulose; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Phosphoserine; Phosphothreonine; Phosphotyrosine; Photometry; Tyrosine | 1993 |
Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo.
Topics: Actin Cytoskeleton; Animals; Cell Compartmentation; Cell Division; Concanavalin A; Cytoskeleton; Dictyostelium; Membrane Proteins; Mutation; Myosins; Octoxynol; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Tyrosine | 1993 |
Identification of a 170 kDa membrane kinase with increased activity in KB-V1 multidrug resistant cells.
Topics: Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Calcium; Carbazoles; Carrier Proteins; Clone Cells; Cyclic AMP; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Humans; Indole Alkaloids; Indoles; KB Cells; Melanoma, Experimental; Membrane Glycoproteins; Mice; Neoplasm Proteins; Phosphatidylserines; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyrroles; Staurosporine; Transfection; Tumor Cells, Cultured; Tyrosine | 1993 |
Phosphorylation of two human neurochordins by mammalian casein kinase 1.
Topics: Adenosine Triphosphate; Adolescent; Autoradiography; Brain; Casein Kinases; Electrophoresis, Polyacrylamide Gel; Female; Humans; Membrane Glycoproteins; Molecular Weight; Nerve Tissue Proteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1993 |
Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR.
Topics: Amino Acid Sequence; Dual-Specificity Phosphatases; Humans; Kinetics; Models, Theoretical; Molecular Sequence Data; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Tyrosine Phosphatases; Substrate Specificity | 1995 |
An inhibitor of p34cdc2/cyclin B that regulates the G2/M transition in Xenopus extracts.
Topics: Animals; Cell Cycle; Cell Membrane; Cell-Free System; Cyclins; Interphase; Membrane Proteins; Mitosis; Molecular Weight; Oocytes; Phosphothreonine; Phosphotyrosine; Rabbits; Xenopus laevis | 1996 |
Crystal structure of the dual specificity protein phosphatase VHR.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Dual Specificity Phosphatase 3; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Sequence Alignment; Substrate Specificity; Water; Yersinia | 1996 |
Phosphotyrosyl protein phosphatase-like activity of a clonal osteoblastic cell line (MC3T3-E1 cell).
Topics: 3T3 Cells; Animals; Cell Line; Clone Cells; Cyclic AMP; Enzyme Inhibitors; Ethers, Cyclic; Histones; Hydrogen-Ion Concentration; Hydrolysis; Mice; Muramidase; Okadaic Acid; Osteoblasts; Peptides; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Vanadates; Zinc | 1995 |
Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells.
Topics: Androstadienes; Animals; Cell Line; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver Neoplasms, Experimental; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Rats; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1996 |
Adducin regulation. Definition of the calmodulin-binding domain and sites of phosphorylation by protein kinases A and C.
Topics: Amino Acid Sequence; Binding Sites; Calmodulin; Calmodulin-Binding Proteins; Chromatography, High Pressure Liquid; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Erythrocytes; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Proteins | 1996 |
Analysis of the phosphoamino acid content of phosphoproteins.
Topics: Amino Acids; Chromatography, Thin Layer; Isotope Labeling; p-Dimethylaminoazobenzene; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1996 |
Characterization of the C-terminal domain of ras-GTPase-activating protein (ras-GAP) as substrate for epidermal growth factor receptor and p60c-src kinase.
Topics: Electrophoresis, Polyacrylamide Gel; Enzyme Activation; ErbB Receptors; GTPase-Activating Proteins; Histones; Humans; Kinetics; Magnesium; Manganese; Ovalbumin; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyglutamic Acid; Polylysine; Proteins; ras GTPase-Activating Proteins; src-Family Kinases; Trypsin; Tumor Cells, Cultured; Tyrosine | 1996 |
Determination of phosphoserine in human pepsinogens.
Topics: Chromatography; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Gastric Juice; Humans; Hydrolysis; Pepsinogens; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1996 |
Sequential dephosphorylation of p34(cdc2) on Thr-14 and Tyr-15 at the prophase/metaphase transition.
Topics: Amino Acid Sequence; Animals; Antibodies; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cloning, Molecular; Female; Kinetics; Metaphase; Molecular Sequence Data; Oocytes; Peptide Fragments; Phosphoprotein Phosphatases; Phosphothreonine; Phosphotyrosine; Prophase; Protein Phosphatase 2; Recombinant Fusion Proteins; Recombinant Proteins; Starfish; Substrate Specificity | 1996 |
Tyrosine phosphorylation of myelin protein PO.
Topics: Animals; Hydrolysis; Male; Myelin P0 Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Vanadates | 1996 |
Insulin promotes and cyclic adenosine 3',5'-monophosphate impairs functional insertion of insulin receptors in the plasma membrane of rat adipocytes: evidence for opposing effects of tyrosine and serine/threonine phosphorylation.
Topics: Adipocytes; Affinity Labels; Animals; Cell Membrane; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Histocompatibility Antigens Class I; Immunoblotting; Insulin; Male; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Type C Phospholipases | 1997 |
Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoprotein.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium-Calmodulin-Dependent Protein Kinases; GRB2 Adaptor Protein; Humans; Isoenzymes; Membrane Proteins; Phospholipase C gamma; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins pp60(c-src); Rats; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Shc Signaling Adaptor Proteins; Signal Transduction; Son of Sevenless Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Transfection; Type C Phospholipases | 1997 |
Are phosphorylated tyrosine residues of certain receptors involved in inducing transitory covalent protein cross-linking?
Topics: Animals; Models, Chemical; Models, Structural; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Receptors, Cell Surface; Receptors, Fc; Signal Transduction; Static Electricity | 1997 |
Biochemical evidence that the phosphorylated tyrosines, serines, and threonines on the aggregated high affinity receptor for IgE are in the immunoreceptor tyrosine-based activation motifs.
Topics: Amino Acid Sequence; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Receptor Aggregation; Receptors, IgE; src-Family Kinases | 1997 |
Analysis of sites of protein phosphorylation.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Sequence Analysis | 1997 |
Phosphorylation of tick-borne encephalitis virus NS5 protein.
Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Blotting, Western; Cells, Cultured; DNA-Directed RNA Polymerases; Encephalitis Viruses, Tick-Borne; Female; Kidney; Kinetics; Mice; Mice, Inbred BALB C; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; RNA, Viral; Swine; Viral Nonstructural Proteins | 1997 |
Posttranslational regulation of Lck and a p36-38 protein by activators of protein kinase C: differential effects of the tumor promoter, PMA, and the non-tumor-promoter, bryostatin.
Topics: Adjuvants, Immunologic; Bryostatins; Carcinogens; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Lactones; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrolides; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; src-Family Kinases; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.
Topics: B7-1 Antigen; CD28 Antigens; Enzyme Activation; Enzyme Inhibitors; Humans; Jurkat Cells; Ligands; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate | 1997 |
EGF receptor phosphorylation is affected by ionizing radiation.
Topics: Adenosine Triphosphate; Cell Division; Cell Line; Cell Membrane; Cesium Radioisotopes; Dose-Response Relationship, Radiation; Epidermal Growth Factor; ErbB Receptors; Gamma Rays; Humans; Kinetics; Methionine; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1997 |
Production of a soluble cyclin B/cdc2 substrate for cdc25 phosphatase.
Topics: Animals; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Fractionation; Cyclin B; Cyclin B1; Glutathione Transferase; HeLa Cells; Humans; Phosphoprotein Phosphatases; Phosphothreonine; Phosphotyrosine; Recombinant Fusion Proteins; Solubility; Substrate Specificity; Xenopus | 1997 |
Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Compartmentation; Cytosol; Insulin; Insulin Receptor Substrate Proteins; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptor, Insulin; Time Factors | 1998 |
Identification of phosphoproteins coupled to initiation of motility in live epididymal mouse sperm.
Topics: Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Epididymis; Humans; Male; Mice; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Sperm Capacitation; Sperm Motility; Spermatozoa | 1998 |
Fragmentation of phosphopeptides in an ion trap mass spectrometer.
Topics: Amino Acid Sequence; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1998 |
PhosphoBase, a database of phosphorylation sites: release 2.0.
Topics: Animals; Bacteria; Databases, Factual; Humans; Internet; Kinetics; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Plants; Protein Kinases; Substrate Specificity; Viruses | 1999 |
Phosphorylation-dephosphorylation states at different sites affect phosphoprotein phosphatase 1 activity.
Topics: Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Phosphatase 1; src-Family Kinases | 1998 |
Correlations in palmitoylation and multiple phosphorylation of rat bradykinin B2 receptor in Chinese hamster ovary cells.
Topics: Acylation; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Mass Spectrometry; Molecular Sequence Data; Palmitates; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Rats; Receptor, Bradykinin B2; Receptors, Bradykinin; Transfection; Trypsin | 1999 |
Inhibitory effect of regucalcin on Ca2+/calmodulin-dependent protein phosphatase activity in rat brain cytosol.
Topics: Animals; Antibodies, Monoclonal; Biomarkers; Brain; Calbindins; Calcineurin; Calcium; Calcium-Binding Proteins; Calmodulin; Carboxylic Ester Hydrolases; Cytosol; Enzyme Activation; Female; Intracellular Signaling Peptides and Proteins; Liver; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Rats, Wistar; S100 Calcium Binding Protein G; S100 Proteins; Sulfotransferases; Trifluoperazine | 1999 |
Heat-shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Enzyme Activation; Fungal Proteins; Gene Expression Regulation, Fungal; Hot Temperature; Humans; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Phosphatase 2; Protein Phosphatase 2C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Signal Transduction; Stress, Physiological | 1999 |
Alternative procedure for two-dimensional separation of phosphoamino acids.
Topics: Autoradiography; Chromatography, Thin Layer; Ninhydrin; Nucleotide Mapping; Peptide Mapping; Phosphoamino Acids; Phosphopeptides; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1999 |
Regulation of Jak2 tyrosine kinase by protein kinase C during macrophage differentiation of IL-3-dependent myeloid progenitor cells.
Topics: Animals; Apoptosis; Catalysis; Cell Differentiation; Cell Division; DNA Replication; Enzyme Activation; Enzyme Induction; Interleukin-3; Isoenzymes; Janus Kinase 2; Macrophages; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Enzyme Activation; Isoenzymes; MAP Kinase Kinase 3; MAP Kinase Kinase 6; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Alignment; Sequence Deletion; Substrate Specificity; Transfection | 2000 |
Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation.
Topics: Animals; beta Catenin; Binding Sites; Cadherins; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Desmoplakins; Embryo, Mammalian; Endothelium, Vascular; gamma Catenin; Humans; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet Endothelial Cell Adhesion Molecule-1; Protein Kinase C; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Umbilical Veins; Yolk Sac | 2000 |
Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast.
Topics: Adaptation, Physiological; Biological Transport; Cell Nucleus; Cytoplasm; Enzyme Activation; Fungal Proteins; Intracellular Signaling Peptides and Proteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Mutation; Osmolar Concentration; Phosphorylation; Phosphothreonine; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sodium Chloride | 2000 |
TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Lymphokines; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Stress, Mechanical; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Tyrosine-phosphorylated extracellular signal--regulated kinase associates with the Golgi complex during G2/M phase of the cell cycle: evidence for regulation of Golgi structure.
Topics: Animals; Antibody Specificity; Cell Cycle; Cell Line; Cell Membrane; CHO Cells; Cricetinae; Cytoplasmic Vesicles; Fluorescent Antibody Technique; G2 Phase; Golgi Apparatus; HeLa Cells; Humans; Macropodidae; Mannosidases; MAP Kinase Kinase 1; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitosis; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases | 2001 |
ERK regulates the hepatocyte growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Butadienes; Cell Line; Culture Media, Serum-Free; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Hepatocyte Growth Factor; Kinetics; Mitogen-Activated Protein Kinases; Nitriles; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphopeptides; Phosphoproteins; Phosphothreonine; Phosphotyrosine; Protein Subunits; Recombinant Fusion Proteins; src Homology Domains | 2001 |
Multiple phosphorylation of membrane-associated calcium-dependent protein serine/threonine kinase in Streptomyces fradiae.
Topics: Autoradiography; Calcium; Cell-Free System; Molecular Weight; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Denaturation; Protein Serine-Threonine Kinases; Streptomyces | 2001 |
14-3-3 protein-activated and autoinhibited forms of plasma membrane H(+)-ATPase.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Arsenicals; Blotting, Western; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Ethylmaleimide; Glycosides; Glycosylation; Hydrogen-Ion Concentration; Immunoblotting; Models, Biological; Molecular Sequence Data; Phosphorylation; Phosphothreonine; Phosphotyrosine; Plant Proteins; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proton-Translocating ATPases; Sequence Homology, Amino Acid; Tyrosine 3-Monooxygenase | 2001 |
Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.
Topics: Amino Acid Sequence; Animals; Caseins; Cattle; Chromatography, Affinity; Molecular Sequence Data; Ovalbumin; Phosphopeptides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Sequence Analysis, Protein; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.
Topics: 14-3-3 Proteins; 3T3 Cells; Animals; Biological Transport; Cell Nucleus; COS Cells; Cytoplasm; Cytosol; Enzyme Inhibitors; Epidermal Growth Factor; Fluorescent Antibody Technique; Immunosorbent Techniques; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Mice; Microscopy, Confocal; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase | 2002 |
Can we infer peptide recognition specificity mediated by SH3 domains?
Topics: Amino Acid Sequence; Binding Sites; Consensus Sequence; Peptides; Phosphothreonine; Phosphotyrosine; Protein Conformation; Proteins; Sequence Alignment; Sequence Homology, Amino Acid; src Homology Domains; Substrate Specificity | 2002 |
General method for the synthesis of caged phosphopeptides: tools for the exploration of signal transduction pathways.
Topics: Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Photolysis; Signal Transduction | 2002 |
Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.
Topics: Binding Sites; Cell Line; Enzyme Activation; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphothreonine; Phosphotyrosine; rap1 GTP-Binding Proteins; ras GTPase-Activating Proteins; Recombinant Proteins; src Homology Domains; src-Family Kinases; Transfection | 2002 |
The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Adhesion; Cell Division; Cell Line; Cell Movement; Electrophoretic Mobility Shift Assay; Feedback, Physiological; Fibroblast Growth Factors; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Mutation; PC12 Cells; Phosphoproteins; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Binding; Proteins; Rats; Receptors, Fibroblast Growth Factor | 2002 |
Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Antibodies, Monoclonal; Antigens, CD; Carrier Proteins; Cytokine Receptor gp130; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Human Growth Hormone; Humans; Immunoblotting; Indoles; Janus Kinase 2; Maleimides; MAP Kinase Kinase 1; Membrane Glycoproteins; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptor, ErbB-2; Recombinant Fusion Proteins; Signal Transduction; Transfection; Ubiquitin-Protein Ligases | 2003 |
An experimental and theoretical study of the 13C and 31P chemical shielding tensors in solid O-phosphorylated amino acids.
Topics: Amino Acids; Carbon Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphorus; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Stereoisomerism | 2003 |
CRP: Cleavage of Radiolabeled Phosphoproteins.
Topics: Humans; Internet; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Radioactive Tracers; Sequence Analysis, Protein; Software | 2003 |
Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants.
Topics: Animals; Blotting, Western; Carcinoma, Lewis Lung; Cytoskeletal Proteins; Down-Regulation; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Mice; Okadaic Acid; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Precipitin Tests; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Tumor Cells, Cultured | 2003 |
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.
Topics: Amino Acid Sequence; Bacillus subtilis; Base Sequence; Conserved Sequence; DNA Primers; Enzyme Activation; Kinetics; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Uridine Diphosphate Glucose Dehydrogenase | 2003 |
Molecular cloning and characterization of a novel dual-specificity phosphatase 23 gene from human fetal brain.
Topics: Adult; Aniline Compounds; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cytoplasm; Dual-Specificity Phosphatases; Fetus; Gene Library; Humans; Organophosphorus Compounds; Phosphothreonine; Phosphotyrosine; Protein Tyrosine Phosphatases; Signal Transduction; Tissue Distribution; Transfection | 2004 |
Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats.
Topics: Animals; Animals, Genetically Modified; Blotting, Western; Calcium; Calcium Chloride; Calcium-Binding Proteins; Calmodulin; Carboxylic Ester Hydrolases; Chelating Agents; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Gene Dosage; Intracellular Signaling Peptides and Proteins; Male; Microsomes, Liver; Okadaic Acid; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfotransferases; Trifluoperazine; Vanadates | 2004 |
Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry.
Topics: Animals; Cattle; Electron Transport Complex I; Female; Fluorescent Dyes; HeLa Cells; Humans; Mitochondria, Heart; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Subunits; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting.
Topics: Alkaline Phosphatase; Blotting, Western; Chromatography, Affinity; Electrophoresis, Gel, Two-Dimensional; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sorbic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways.
Topics: Apoptosis; Asbestos, Crocidolite; Buthionine Sulfoximine; Caspases; Cell Line; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Ferric Compounds; Humans; JNK Mitogen-Activated Protein Kinases; Lung; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphothreonine; Phosphotyrosine; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Quaternary Ammonium Compounds; Signal Transduction; Time Factors | 2007 |
Role for non-proteolytic control of M-phase-promoting factor activity at M-phase exit.
Topics: Animals; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cyclin B1; Enzyme Activation; Female; Humans; Meiosis; Metaphase; Mitosis; Oocytes; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Xenopus laevis; Xenopus Proteins | 2007 |
A multiplexed protein kinase assay.
Topics: Cell Extracts; DNA; Enzyme Activation; HeLa Cells; Humans; Isotope Labeling; Molecular Probe Techniques; Oligonucleotides; Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Sensitivity and Specificity; Solutions; Substrate Specificity | 2007 |
Cholesterol depletion alters detergent-specific solubility profiles of selected tight junction proteins and the phosphorylation of occludin.
Topics: Animals; Cell Membrane; Cells, Cultured; Centrifugation; Cholesterol; Cholic Acids; Claudin-1; Detergents; Dogs; Electric Impedance; Epithelial Cells; Membrane Proteins; Occludin; Octoxynol; Palmitic Acid; Phosphorylation; Phosphothreonine; Phosphotyrosine; Solubility; Tight Junctions; Ultraviolet Rays | 2007 |
UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbohydrate Dehydrogenases; Electrophoresis; Isoenzymes; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Staphylococcus aureus; Substrate Specificity | 2007 |
The activation and inhibition of cyclin-dependent kinase-5 by phosphorylation.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Computer Simulation; Crystallography, X-Ray; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Enzyme Activation; Humans; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Software; Substrate Specificity; Thermodynamics | 2007 |
Proteomic approach for caudal trauma-induced acute phase proteins reveals that creatine kinase is a key acute phase protein in amphioxus humoral fluid.
Topics: Acute-Phase Proteins; Animals; Antibodies, Monoclonal; Chordata; Cloning, Molecular; Creatine Kinase; Gene Expression Regulation; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteomics; Spectrometry, Mass, Electrospray Ionization; Time Factors; Wound Healing | 2007 |
Phosphopeptide elution times in reversed-phase liquid chromatography.
Topics: Amino Acid Sequence; Chromatography, Liquid; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Predictive Value of Tests; Proteome; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors; Trifluoroacetic Acid; Trypsin | 2007 |
Phospho.ELM: a database of phosphorylation sites--update 2008.
Topics: Databases, Protein; Internet; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Sequence Alignment; Sequence Analysis, Protein; Software | 2008 |
Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase.
Topics: Animals; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Proteins; Binding Sites; Catalysis; Cell Line; Crystallography, X-Ray; Dual Specificity Phosphatase 6; Immunoprecipitation; Lipoproteins; Lyases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 7; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Folding; Salmonella typhimurium; Shigella flexneri; Tyrosine | 2007 |
Ezrin is a specific and direct target of protein tyrosine phosphatase PRL-3.
Topics: Catalysis; Cytoskeletal Proteins; Endothelial Cells; HCT116 Cells; Humans; Mutant Proteins; Neoplasm Proteins; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Tyrosine Phosphatases; RNA Interference; Substrate Specificity; Tetradecanoylphorbol Acetate | 2008 |
TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism.
Topics: Animals; Apoptosis; Benzamides; Caseins; Cells, Cultured; Dioxoles; Epithelial Cells; Gene Expression Regulation; Genes, Dominant; Humans; Janus Kinase 2; Mammary Glands, Animal; Phosphoserine; Phosphothreonine; Phosphotyrosine; Prolactin; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Smad3 Protein; STAT5 Transcription Factor; Transforming Growth Factor beta | 2008 |
Phosphoamino acid analysis.
Topics: Alkalies; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Hydrogen-Ion Concentration; Hydrolysis; Phosphoamino Acids; Phosphothreonine; Phosphotyrosine | 2001 |
Large-scale phosphorylation mapping reveals the extent of tyrosine phosphorylation in Arabidopsis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Conserved Sequence; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Plant Proteins; Protein Structure, Tertiary; Proteome; Sequence Homology, Amino Acid | 2008 |
Phosphoprotein profiling by PA-GeLC-MS/MS.
Topics: Chromatography, Liquid; Databases, Factual; Fungal Proteins; Humans; K562 Cells; Multiprotein Complexes; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphothreonine; Phosphotyrosine; Proteome; Tandem Mass Spectrometry; Yeasts | 2008 |
Phosphorylation and kinetics of mammalian cytochrome c oxidase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Cattle; Electron Transport Complex IV; Kinetics; Mitochondria, Heart; Myocardium; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2008 |
The role of phosphorylated residues in peptide-peptide noncovalent complexes formation.
Topics: Arginine; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Static Electricity | 2008 |
ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; CHO Cells; Cricetinae; Cricetulus; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibrosarcoma; Humans; Molecular Sequence Data; Mutant Proteins; Phosphorylation; Phosphothreonine; Phosphotyrosine; Receptor, ErbB-2; Receptors, Somatotropin; Signal Transduction; Ubiquitination | 2008 |
The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.
Topics: 4-Butyrolactone; beta Catenin; Caco-2 Cells; Cadherins; Cytoplasm; Epithelial Cells; Genistein; Homoserine; Humans; Intercellular Junctions; Membrane Proteins; Occludin; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Pseudomonas aeruginosa; Quorum Sensing; Staurosporine; Zonula Occludens-1 Protein | 2009 |
Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins.
Topics: Animals; Humans; Mass Spectrometry; Mitochondrial Proteins; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 2009 |
Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Death; Cell Survival; Dual-Specificity Phosphatases; Embryonic Development; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mammals; Mass Spectrometry; Mitogen-Activated Protein Kinase Phosphatases; Morphogenesis; Myristic Acid; Phosphoprotein Phosphatases; Phosphoserine; Phosphothreonine; Phosphotyrosine; Signal Transduction; Substrate Specificity; Transfection | 2010 |
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cognition; Enzyme Activation; Female; Humans; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Phosphoserine; Phosphothreonine; Phosphotyrosine; Up-Regulation | 2011 |
Antibody-free peptide substrate screening of serine/threonine kinase (protein kinase A) with a biotinylated detection probe.
Topics: Amino Acid Sequence; Antibodies; Biotin; Cyclic AMP-Dependent Protein Kinases; Peptide Library; Peptides; Phosphorylation; Phosphothreonine; Phosphotyrosine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptavidin; Substrate Specificity | 2011 |
Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling.
Topics: Animals; Cell Line, Tumor; Chromatography, Affinity; Computational Biology; Ephrin-B1; Immunoprecipitation; Isotope Labeling; Mice; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Interaction Mapping; Protein Interaction Maps; Proteomics; Rats; Receptors, Eph Family; Signal Transduction; Titanium | 2011 |
Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor.
Topics: Bradykinin; Cell Line, Tumor; Cell Membrane; Diacylglycerol Kinase; Endosomes; Enzyme Activation; ErbB Receptors; Gene Silencing; Green Fluorescent Proteins; HEK293 Cells; Humans; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Binding; Protein Kinase C; Protein Transport; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 2012 |
Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.
Topics: Active Transport, Cell Nucleus; Apoptosis; Cell Nucleus; Deoxycholic Acid; Green Fluorescent Proteins; GTPase-Activating Proteins; HeLa Cells; Humans; Nuclear Export Signals; Nuclear Pore; Nucleocytoplasmic Transport Proteins; Phosphorylation; Phosphothreonine; Phosphotyrosine; Polysorbates; Pregnancy Proteins; Protein Transport; ran GTP-Binding Protein; Receptors, Cytoplasmic and Nuclear; RNA Transport; RNA, Messenger; RNA, Transfer; Signal Transduction; Sirolimus | 2012 |
Different modes of endothelial-smooth muscle cell interaction elicit differential β-catenin phosphorylations and endothelial functions.
Topics: Animals; Antigens, CD; beta Catenin; Bone Morphogenetic Protein Receptors, Type II; Bone Morphogenetic Proteins; Cadherins; Cattle; Cell Adhesion; Cell Communication; Cell Compartmentation; Cell Membrane Permeability; Connexin 43; Human Umbilical Vein Endothelial Cells; Models, Biological; Monocytes; Myocytes, Smooth Muscle; Paracrine Communication; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; Proteolysis; Smad5 Protein; Ubiquitin; Vascular Cell Adhesion Molecule-1 | 2014 |
The family-wide structure and function of human dual-specificity protein phosphatases.
Topics: Catalytic Domain; Crystallography, X-Ray; Cysteine; Dual-Specificity Phosphatases; Enzyme Inhibitors; Escherichia coli; Humans; Hydrolysis; Models, Molecular; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Phosphotyrosine; Phylogeny; Protein Structure, Secondary; Recombinant Proteins; Signal Transduction; Structural Homology, Protein; Substrate Specificity | 2014 |
Expanded cellular amino acid pools containing phosphoserine, phosphothreonine, and phosphotyrosine.
Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genetic Engineering; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins | 2014 |
Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells.
Topics: Bronchioles; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase 4; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanotubes, Carbon; Nitrogen; Phosphothreonine; Phosphotyrosine; Photoelectron Spectroscopy; Reactive Oxygen Species; Risk Assessment; Spectrum Analysis, Raman; Time Factors; Toxicity Tests; X-Ray Diffraction | 2015 |
Crystal structure of the human dual specificity phosphatase 1 catalytic domain.
Topics: Binding Sites; Catalytic Domain; Crystallography, X-Ray; Dual Specificity Phosphatase 1; Humans; Maltose-Binding Proteins; Models, Molecular; Phosphothreonine; Phosphotyrosine; Protein Conformation; Substrate Specificity; Sulfates | 2018 |
Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Helicobacter Infections; Helicobacter pylori; Humans; Models, Biological; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Transport; Proto-Oncogene Proteins c-abl | 2019 |
Dual specificity phosphatase 7 drives the formation of cardiac mesoderm in mouse embryonic stem cells.
Topics: Animals; Dual Specificity Phosphatase 1; Dual-Specificity Phosphatases; Mesoderm; Mice; Mitogen-Activated Protein Kinases; Mouse Embryonic Stem Cells; Phosphoserine; Phosphothreonine; Phosphotyrosine | 2022 |