phosphotyrosine has been researched along with phosphoserine in 348 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (18.68) | 18.7374 |
| 1990's | 167 (47.99) | 18.2507 |
| 2000's | 83 (23.85) | 29.6817 |
| 2010's | 29 (8.33) | 24.3611 |
| 2020's | 4 (1.15) | 2.80 |
| Authors | Studies |
|---|---|
| Gelman, MS; Hadcock, JR; Malbon, CC; Port, JD | 1 |
| Aaronson, SA; Bottaro, DP; Chan, A; Ishibashi, T; Miki, T | 1 |
| Min, HK; Park, DJ; Rhee, SG | 1 |
| Bordwell, KL; Mooney, RA | 1 |
| Atherton-Fessler, S; Parker, LL; Piwnica-Worms, H | 1 |
| Li, P; Roberts, TM; Williams, NG | 1 |
| Afar, DE; Bell, JC; Ben-David, Y; Douville, EM; Howell, BW; Letwin, K; Pawson, T; Tannock, L | 1 |
| Baltensperger, K; Czech, MP; Lewis, RE; Ross, AH; Vissavajjhala, P; Woon, CW | 1 |
| Crews, CM; Erikson, RL | 1 |
| Baggio, B; Bordin, L; Clari, G; Moret, V | 1 |
| Farrar, WL; Linnekin, D; Park, LS | 1 |
| Chiang, TM | 2 |
| Abraham, RT; Dick, CJ; Einspahr, KJ; Leibson, PJ | 1 |
| Bird, TA; Saklatvala, J | 1 |
| Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P | 1 |
| Anderson, SR; Malencik, DA; Zhao, ZZ | 1 |
| Clinton, GM; Li, SW; Lin, YZ | 1 |
| Granot, Y; Schrier, RW; Van Putten, V | 1 |
| Cozzone, AJ; Dadssi, M | 1 |
| Iwashita, S; Mitsui, K | 2 |
| App, H; Baccarini, M; Rapp, UR; Sabatini, DM; Stanley, ER | 1 |
| Farrar, WL; Linnekin, D | 1 |
| Carroll, MP; Clark-Lewis, I; May, WS; Rapp, UR | 1 |
| Biener, Y; Zick, Y | 1 |
| Ballou, LM; Luther, H; Thomas, G | 1 |
| Contreras, ML; Fink, D; Guroff, G; Kim, HS; Kim, UH; Park, DJ; Rhee, SG | 1 |
| Clack, B; Ellis, L; Tavaré, JM | 1 |
| Carroll, RB; Samad, A | 1 |
| Marshall, SH; Muñoz, G | 1 |
| Meggio, F; Perich, JW; Pinna, LA; Reynolds, EC | 1 |
| Bayer, H; Buchner, K; Hucho, F; Meyer, HE; Schroeder, W | 1 |
| Denton, RM; Issad, T; Tavaré, JM | 1 |
| Byun, SM; Kang, KR; Kang, YS; Kim, CW; Kim, YW | 1 |
| Abdel-Ghany, M; Koland, J; Racker, E; Revis-Gupta, S | 1 |
| Ahn, NG; Boulton, TG; Bratlien, RL; Cobb, MH; Ericsson, L; Krebs, EG; Panayotatos, N; Radziejewska, E; Seger, R; Yancopoulos, GD | 1 |
| Friedmann, M; Hoover, D; Magnuson, NS; Reeves, R | 1 |
| Kataoka, H; Makita, M; Sakiyama, N | 1 |
| Iqbal, K; Murthy, LR | 1 |
| Cohen, P; Gómez, N | 1 |
| Kole, HK; Lenard, J | 1 |
| Kamps, MP | 1 |
| Ringer, DP | 1 |
| Anderson, NG; Erickson, AK; Ray, LB; Sturgill, TW | 1 |
| Kaplan, NO; Knowles, AF; Leis, JF | 1 |
| Cohen, S; Sawyer, ST | 1 |
| Aitken, A; Morrice, N | 1 |
| Mueller-Lantzsch, N; Roeckel, D | 1 |
| Carlomagno, L; Huebner, VD; Matthews, HR | 1 |
| Hollenberg, MD; Pallen, CJ; Valentine, KA; Wang, JH | 1 |
| Londesborough, J | 1 |
| Bretscher, A; Cooper, JA; Gould, KL; Hunter, T | 1 |
| Rosen, OM; Stadtmauer, L | 1 |
| Casnellie, JE; Lamberts, RJ | 1 |
| Lau, AF | 1 |
| Ziemiecki, A | 1 |
| Bárány, K; Bárány, M; Csabina, S; Mougios, V | 1 |
| Hunter, T; Patschinsky, T; Sefton, BM | 1 |
| Bergeron, JJ; Kay, DG; Khan, MN; Lai, WH; Posner, BI; Uchihashi, M | 1 |
| Blumenthal, DK; Chan, CP; Gallis, B; Krebs, EG; Pallen, CJ; Wang, JH | 1 |
| Harford, JB; Klausner, RD; Patel, MD; Samelson, LE; Weissman, AM | 1 |
| Barbaric, S; Donella-Deana, A; Lopandic, K; Pinna, LA | 1 |
| Etheredge, RW; Glimcher, MJ | 1 |
| Bauer, H; Niemann, H; Simon, E; Snoek, GT; Tamura, T | 1 |
| Niedbalski, JS; Ringer, DP | 1 |
| Destrée, OH; Sluyser, M | 1 |
| Belzer, SK; Collett, MS | 1 |
| David-Pfeuty, T; Guesdon, F | 1 |
| Acquaviva, AM; Consiglio, E; De Luca, M; Formisano, S; Gallo, A; Liguoro, D; Santisteban, P; Shifrin, S; Vittorio, T; Yeh, HJ | 1 |
| Huang, ES; Muganda-Ojiaku, PM | 1 |
| Rosen, OM | 1 |
| Balasubramanian, AS; Panneerselvam, K; Ramamoorthy, S | 1 |
| Barel, M; Delcayre, AX; Fiandino, A; Frade, R | 1 |
| Clarke, S; Drickamer, K; Lou, LL; McFadden, PN | 1 |
| Amatruda, JM; Roncone, AM; Sparks, CE; Sparks, JD | 1 |
| Cooper, JA; Kazlauskas, A | 1 |
| Dasgupta, JD; Rudd, CE; Schlossman, SF; Trevillyan, JM; Wong, LL | 1 |
| Bernier, M; Laird, DM; Lane, MD | 1 |
| Colca, JR; McCroskey, MC; Pearson, JD | 1 |
| Johnson, PJ; Kmiecik, TE; Shalloway, D | 1 |
| Eigenbrodt, E; Presek, P; Reinacher, M | 1 |
| Sale, GJ; Smith, DM | 1 |
| Foster, R; Martin, GS; Thorner, J | 1 |
| Beachey, EH; Kotb, M | 1 |
| Hunter, T; Meisenhelder, J; Rhee, SG; Suh, PG | 1 |
| Boland, D; Goren, HJ; Neufeld, E | 1 |
| Gjika, HB; Levine, L; Van Vunakis, H | 1 |
| Acuto, O; Alcover, A; Danielian, S; Fagard, R; Fischer, S | 1 |
| Dass, C | 1 |
| Clinton, GM; Huang, AS | 1 |
| Sen, A | 1 |
| Berdot, C; Elliott, T; Hunter, T; Patschinsky, T; Sefton, BM | 1 |
| Blith, DL; Häring, HU; Kahn, CR; Karlsson, FA; Kasuga, M; Zick, Y | 1 |
| Adkins, B; Hunter, T; Sefton, BM | 1 |
| Fujitaki, JM; Smith, RA; Yang, JC | 1 |
| Cozzone, AJ; Manai, M | 1 |
| Kaplan, NO; Leis, JF | 1 |
| Congote, LF | 1 |
| Capony, JP; Demaille, JG | 1 |
| Brugge, JS; Darrow, D; Lipsich, LA; Yonemoto, W | 1 |
| Chang, WC; Chou, CK; Lee, ML; Lee, SC | 1 |
| Gootwine, E; Hortsch, M; Schlessinger, J; Webb, CG | 1 |
| Buss, JE; Stull, JT | 1 |
| Fehlmann, M; Gazzano, H; Kowalski, A; Van Obberghen, E | 1 |
| Foulkes, JG | 1 |
| Erikson, RL | 1 |
| Dasgupta, JD; Garbers, DL; Swarup, G | 1 |
| Auricchio, F; Migliaccio, A; Rotondi, A | 1 |
| Martensen, TM | 1 |
| Fukunaga, R; Nagata, S; Pan, CX; Yonehara, S | 1 |
| Liu, WK; Yang, SD; Yen, SH; Yu, JS | 1 |
| Hakomori, S; Igarashi, Y; Kitamura, K; Zhou, Q | 1 |
| Donella-Deana, A; Klee, C; Krinks, MH; Pinna, LA; Ruzzene, M | 1 |
| Berti, L; Häring, H; Kellerer, M; Kroder, G; Mosthaf, L; Mushack, J; Seedorf, K; Seffer, E; Tippmer, S | 1 |
| King, SM; Witman, GB | 1 |
| Pratt, MM; Salathe, M; Wanner, A | 1 |
| Huganir, RL; Wagner, KR | 1 |
| Berk, BC; Bernstein, KE; Delafontaine, P; Klein, JD; Marrero, MB; Paxton, WG | 1 |
| Anderson, MT; Gitler, C; Herzenberg, LA; Staal, FJ; Staal, GE | 1 |
| Daya-Makin, M; Hogg, JC; Lipp, M; Mogentale, TL; Parchomchuk, J; Pelech, SL; Sanghera, JS | 1 |
| DePaoli-Roach, AA; Fiol, CJ; Roach, PJ; Wang, QM | 1 |
| Fallon, RJ; Perlmutter, DH; Sippel, CJ | 1 |
| Banville, D; Bouchard, P; Dumas, F; Fischer, EH; Shen, SH; Zhao, Z | 1 |
| Stover, DR; Walsh, KA | 1 |
| Damuni, Z; Li, M; Xiong, H | 1 |
| Heegaard, NH | 1 |
| Benjamin, CW; Jones, DA; Linseman, DA | 1 |
| Ali, N; Chua, NH; Halfter, U | 1 |
| Casey, M; Pai, LM; Peifer, M | 1 |
| Cherqui, G; Plas, C; Zachayus, JL | 1 |
| Abu-Lawi, KI; Sultzer, BM | 1 |
| Hoffmann, R; Kalbitzer, HR; Reichert, I; Wachs, WO; Zeppezauer, M | 1 |
| Marshall, SH; Muñoz, GE | 1 |
| Caldenhoven, E; Coffer, P; Heinrich, PC; Horn, F; Kruijer, W; Lütticken, C; Schindler, C; Schwartz, C; Yuan, J | 1 |
| Kinsey, WH | 1 |
| Giasson, E; Meloche, S | 1 |
| Adam, LP; Gunst, SJ; Pavalko, FM; Walker, TL; Wu, MF | 1 |
| Kumar, R | 1 |
| Pillay, I; Sharma, SV | 1 |
| Khan, MA; Kobayashi, S; Nakagawa, H; Okada, M; Okumura, N | 1 |
| Hoffman, FJ; Roder, HM; Schröder, W | 1 |
| Fabian, H; Lang, E; Mantsch, HH; Otvos, L; Szendrei, GI | 1 |
| Barlati, S; Bona, C; De Petro, G; Paracini, F; Tonelli, M | 1 |
| Hunter, T; Tracy, S; van der Geer, P | 1 |
| Fujiki, N; Hamaguchi, M; Miyadai, T; Mutoh, T; Tokuda, A | 1 |
| Lacombe, JM; Mora, N; Pavia, AA | 1 |
| Benarous, R; Bodéus, M; Bougeret, C; Marie-Cardine, A; Ramos-Morales, F | 1 |
| Cuveele, JF; de Witte, PA; Merlevede, WJ; Vandenheede, JR | 1 |
| Asamoah, KA; Carter, WG; Sale, GJ | 1 |
| Darnell, JE; Wen, Z; Zhong, Z | 1 |
| Maloy, S; Ostrovsky, PC | 1 |
| Biesinger, B; Desrosiers, RC; Friedrich, U; Jun, T; Jung, JU; Lang, SM; Roberts, TM | 1 |
| Parry, R; Sansom, D; Ward, S; Westwick, J; Wilson, A | 1 |
| Lombardini, JB; Props, C | 1 |
| Fujimoto, J; Hatai, M; Mogi, A; Nagamachi, Y; Soga, H; Takenoshita, S; Yamamoto, T; Yaoi, Y; Yokota, J | 1 |
| Bureau, MH; Laschet, JJ | 1 |
| Ploegh, HL; Schaap, D; van Blitterswijk, WJ; van der Bend, RL; van der Wal, J | 1 |
| Cleghon, V; Kaplan, DR; Rabin, SJ | 1 |
| Coleman, TR; Dunphy, WG; Tang, Z | 1 |
| Inagami, T; Nakajo, S | 1 |
| Blackstone, CD; Huganir, RL; Moss, SJ | 1 |
| Donella-Deana, A; Eisermann, B; Heber, M; Hoffmann-Posorske, E; Hutton, T; Korte, H; Meyer, HE; Perich, JW; Wegner, A; Weigt, C | 1 |
| Kataoka, H; Makita, M; Nakai, K | 1 |
| Bell, SM; Connolly, DC; Degen, JL; Maihle, NJ | 1 |
| Livingston, JN; Moss, AM | 1 |
| Egelhoff, TT; Lee, RJ; Spudich, JA | 1 |
| Elizarov, SM; Preobrazhensky, AA | 1 |
| Goldberg, GS; Lau, AF | 1 |
| Chen, L; Wu, L; Zhang, ZY | 1 |
| Bukrinskaya, AG; Ghorpade, A; Heinzinger, NK; Lewis, RE; Smithgall, TE; Stevenson, M | 1 |
| Chung, J; Park, I; Shin, J; Strominger, JL; Walsh, CT; Yun, Y | 1 |
| Basu, L; Blatt, L; Constantinescu, SN; Croze, E; Mullersman, JE; Murti, A; Pfeffer, LM; Shi, W; Yang, CH | 1 |
| Lapko, VN; Song, PS; Wells, TA | 1 |
| Denu, JM; Dixon, JE; Saper, MA; Yuvaniyama, J | 1 |
| Deyama, Y; Hisada, Y; Matsumoto, A; Okamoto, T; Suzuki, K; Yoshimura, Y | 1 |
| Goldstein, BJ; Li, PM | 1 |
| Bodor, O; Gohr, L; Kunz, W; Schmidt, J | 1 |
| Chew, BG; Jelinski, LW; Michal, CA; Simmons, AH; Zax, DB | 1 |
| Appella, E; Roller, PP; Sakaguchi, K | 1 |
| Bittman, R; Liliom, K; Swords, B; Tigyi, G | 2 |
| Bennett, V; Hughes, CA; Matsuoka, Y | 1 |
| Agostinis, PM; Cuveele, JF; de Witte, PA; Merlevede, WJ | 1 |
| Borowski, P; Heiland, M; Kornetzky, L; Laufs, R; Roloff, S; Weber, W | 1 |
| Foltmann, B; Jensen, AL | 1 |
| Asamoah, KA; Atkinson, PG; Carter, WG; Sale, GJ | 1 |
| Bianchi, R; Eichberg, J; Iyer, S; Rowe-Rendleman, CL | 1 |
| Eriksson, JW; Lönnroth, P; Smith, U; Wesslau, C | 1 |
| Göke, M; Kanai, M; Podolsky, DK; Tsunekawa, S | 1 |
| Ariatti, M; Hawtrey, AO; Van Jaarsveld, PP | 1 |
| Duclos, B; Durocher, Y; Grangeasse, C; Haftek, M; Schmitt, D; Serres, M | 1 |
| Metzger, H; Pribluda, C; Pribluda, VS | 1 |
| Aitken, A; Learmonth, M | 1 |
| Abo, A; Camaur, D; Gallay, P; Song, J; Swingler, S; Trono, D | 1 |
| Bachvalova, VN; Maksimova, TG; Matveeva, VA; Morozova, OV; Tsekhanovskaya, NA | 1 |
| Ansotegui, IJ; Galron, D; Isakov, N | 1 |
| Bellis, SL; Curtis, MS; Perrotta, JA; Turner, CE | 1 |
| Kennelly, PJ; Solow, B; Young, JC | 1 |
| Olive, D; Parry, RV; Sansom, DM; Ward, SG; Westwick, J | 1 |
| Balaban, N; Goldkorn, T; Matsukuma, K; Shannon, M | 1 |
| Alessi, DR; Cohen, P; Shaw, M | 1 |
| Frank, DA; Mahajan, S; Ritz, J | 1 |
| Bortecen, KH; Efstathiou, JA; Kidd, M; Luque, EA; Modlin, IM; Tang, LH; Tarasova, NI | 1 |
| Pawson, T; Scott, JD | 1 |
| Corbin, J; Imagawa, T; Kaya, S; Kikkawa, U; Mårdh, S; Mori, M; Shimada, A; Taniguchi, K; Togawa, K | 1 |
| Bouchie, JL; Feener, EP; Folli, F; Hansen, H; Kahn, CR | 1 |
| Hsu, SM; Lin, S | 1 |
| Barker, SA; Caldwell, KK; Pfeiffer, JR; Wilson, BS | 1 |
| Cheatham, B; Emkey, R; Inoue, G; Kahn, CR | 1 |
| Gooley, AA; Packer, NH; Williams, KL; Yan, JX | 1 |
| Sun, H | 1 |
| Allen, PM; Graves, PR; Hsu, AL; Piwnica-Worms, H; Shaw, AS; Shih, NY; Tanner, JW; Thorson, JA; Yu, LW | 1 |
| Mollerup, S; Rivedal, E; Sanner, T; Vikhamar, G | 1 |
| Bracho, GE; Tash, JS | 1 |
| DeGnore, JP; Qin, J | 1 |
| Blom, N; Brunak, S; Kreegipuu, A | 1 |
| Peterson, CA; Sarbassov, DD | 1 |
| Bachmeyer, C; Mak, CH; Wu, LC; Yu, CY | 1 |
| Bhat, GJ; Gunaje, JJ; Idell, S; Raghu, G | 1 |
| Barinaga, M | 1 |
| Godovac-Zimmermann, J; Müller-Esterl, W; Nyakatura, E; Roos, M; Soskic, V | 1 |
| Hamano, T; Yamaguchi, M | 1 |
| Nguyen, AN; Shiozaki, K | 1 |
| Duclos, B; Grangeasse, C; Riberty, M; Vaganay, E | 1 |
| Goodyear, LJ; Markuns, JF; Wojtaszewski, JF | 1 |
| Braga, VM; Cano, A; Espada, J; Pérez-Moreno, M; Rodriguez-Viciana, P | 1 |
| Mercurio, AM; Rabinovitz, I; Toker, A | 1 |
| Bagossi, P; Boross, P; Copeland, TD; Louis, JM; Majerova, E; Oroszlan, S; Tözsér, J | 1 |
| Baron, R; Bartkiewicz, M; Houghton, A | 1 |
| Fiebich, BL; Hocke, G; Huell, M; Machein, U; Schumann, G | 1 |
| Bradshaw, JM; Mitaxov, V; Waksman, G | 1 |
| Junttila, I; Kovanen, PE; Li, W; Saharinen, P; Silvennoinen, O; Takaluoma, K; Valmu, L | 1 |
| Heads, RJ; Marber, MS; Mockridge, JW | 1 |
| Gandour, RD; Kennelly, PJ; Meadows, CA; Potts, M; Savle, PS; Shelton, TE | 1 |
| Cheung, L; Ilan, N; Madri, JA; Pinter, E | 1 |
| Annan, RS; Chen, SL; Creasy, CL; Kassis, S; Lee, JC; Livi, GP; Melhuish, T | 1 |
| Morrison, T; Stith, BJ; Waggoner, L; Whitworth-Langley, L | 1 |
| Kruijer, W; Schuringa, JJ; Vellenga, E; Wierenga, AT | 1 |
| Decker, T; Kovarik, P | 1 |
| Hasegawa, H; Isagawa, T; Kawamata, T; Mukai, H; Oishi, K; Ono, Y; Tanaka, C; Taniguchi, T | 1 |
| Harris, MB; Ju, H; Liang, H; Venema, RC; Venema, VJ; Zou, R | 1 |
| Haselmann, KF; Jensen, ON; Olsen, JV; Stensballe, A; Zubarev, RA | 1 |
| Cochran, BH; Fanburg, BL; Guan, KL; Simon, AR; Stewart, S; Vikis, HG | 1 |
| Berg, AH; Engelman, JA; Lewis, RY; Lisanti, MP; Scherer, PE | 1 |
| Corson, MA; Gallis, B; Kim, F | 1 |
| Foley, AG; Gallagher, HC; Murphy, KJ; Regan, CM | 1 |
| Bagley, CJ; Guthridge, MA; Lopez, AF; Stomski, FC; Woodcock, JM | 1 |
| Arlinghaus, RB; Campbell, M; Gordon, W; Sun, T | 1 |
| Dajani, R; Dale, TC; Fraser, E; Good, V; Pearl, LH; Roe, SM; Young, N | 1 |
| Danilenko, VN; Elizarov, SM | 1 |
| Belsanti, G; Davalli, AM; Giorgino, F; Giorgino, R; Laviola, L; Napoli, R; Perrini, S; Weir, GC | 1 |
| Benovic, JL; Chalmers, C; Cook, SJ; Johnston, E; Palmer, TM; Pronin, A; Watterson, KR | 1 |
| Martín-Romero, C; Sánchez-Margalet, V | 1 |
| Gotoh, B; Komatsu, T; Takeuchi, K; Yokoo, J | 1 |
| Gutkind, JS; Sanchez-Arevalo, VJ; Sanchez-Prieto, R; Servitja, JM | 1 |
| Bennett, KL; Jensen, ON; Moniatte, M; Podtelejnikov, AV; Stensballe, A | 1 |
| Luo, Z; Ruderman, N; Song, Y; Wen, R; Xiang, X; Yuan, M | 1 |
| Chen, GY; Lesaicherre, ML; Uttamchandani, M; Yao, SQ | 1 |
| Berger, J; Dallas-Yang, Q; Doebber, T; Jiang, G; Li, Z; Liu, F; Moller, DE; Shen, X; Szalkowski, D; Wu, M; Zhang, BB; Zhou, G | 1 |
| Kawai, H; Nie, L; Yuan, ZM | 1 |
| Imperiali, B; Rothman, DM; Vázquez, ME; Vogel, EM | 1 |
| Jackson, JL; Young, MR | 2 |
| Arvanitis, DN; Boggs, JM; Yang, W | 1 |
| Carey, KD; Pessin, JE; Stork, PJ; Watson, RT | 1 |
| Liu, SW; Meisinger, J; Young, MR | 1 |
| Frank, SJ; Huang, Y; Jiang, J; Kim, SO | 1 |
| Assfeld, X; Cartier, A; Ganicz, K; Gardiennet, C; Olejniczak, S; Potrzebowski, MJ; Tekely, P | 1 |
| Bouzakri, K; Espinosa, S; Gual, P; Guebre-Egziabher, F; Laville, M; Le Marchand-Brustel, Y; Riou, JP; Roques, M; Tanti, JF; Vidal, H | 1 |
| Abrahamsen, H; Andersson, Y; Christoffersen, T; Guren, TK; Susa, M; Thoresen, GH; Ødegård, J; Østby, E | 1 |
| Haystead, TA; Mackey, AJ; Pearson, WR | 1 |
| Boël, G; Decottignies, P; Deutscher, J; Doublet, P; Gillet, S; Grangeasse, C; Jamet, E; Le Maréchal, P; Mazé, A; Mijakovic, I; Poncet, S | 1 |
| Augenlicht, L; Huang, J; Klampfer, L; Sasazuki, T; Shirasawa, S | 1 |
| Batty, IH; Downes, CP; Fleming, IN | 1 |
| Andreozzi, F; Laratta, E; Perticone, F; Sciacqua, A; Sesti, G | 1 |
| Fukaya, Y; Yamaguchi, M | 1 |
| Aggeler, R; Capaldi, RA; Goodman, TN; Patton, WF; Schulenberg, B | 1 |
| Boura-Halfon, S; Herschkovitz, A; Leroith, D; Liu, YF; Paz, K; Ronen, D; Zick, Y | 1 |
| Erl, W; Kim, HJ; Vosseler, CA; Weber, PC | 1 |
| Antrobus, R; Botting, CH; Coote, PJ; Makrantoni, V | 1 |
| Lowe, CR; Roque, AC | 1 |
| Franz, KJ; Liu, LL | 1 |
| Nakazawa, A; Osuka, K; Tokuda, M; Usuda, N; Watanabe, Y; Yamauchi, K; Yoshida, J | 1 |
| Argetsinger, LS; Carter-Su, C; Cline, JM; Jensen, ON; Kouadio, JL; Mazurkiewicz-Munoz, AM; Stensballe, A | 1 |
| Houle, F; Huot, J; Le Boeuf, F; Sussman, M | 1 |
| Bijli, KM; Fazal, F; Minhajuddin, M; O'Reilly, MA; Platanias, LC; Rahman, A | 1 |
| Badal, S; Brown, PD; Morrison, S; Ragoobirsingh, D | 1 |
| Berna, MJ; Hoffmann, KM; Jensen, RT; Mantey, SA; Pace, A; Tapia, JA; Thill, M | 1 |
| Guthridge, MA; Lopez, AF | 1 |
| Barker, DL; Hachmann, JP; Kermani, BG; Kozlov, IA; Lebl, M; Melnyk, PC; Musmacker, J; Nelson, N; Shevchenko, V; Shults, MD; Srinivasan, A; Zhao, C | 1 |
| He, D; Natarajan, V; Salgia, R; Spannhake, EW; Stern, R; Usatyuk, PV; Zhao, Y | 1 |
| Cozzone, AJ; Duclos, B; Grangeasse, C; Soulat, D; Vaganay, E | 1 |
| Chen, CS; Fong, JH; Khan, M; Ng, AP; Nin, DS; Venkataraman, D | 1 |
| Gao, YY; Li, H; Li, QF; Liu, R; Peng, XX; Wang, SY; Zhang, DF; Zhuang, ZH | 1 |
| Camp, DG; Kim, J; Moore, RJ; Petritis, K; Shen, Y; Smith, RD | 1 |
| Chica, C; Diella, F; Gibson, TJ; Gould, CM; Via, A | 1 |
| Geahlen, RL; Harrison, ML; Li, M; Ong, SS; Rajwa, B; Thieu, VT | 1 |
| Andrabi, S; Gjoerup, OV; Kean, JA; Roberts, TM; Schaffhausen, B | 1 |
| Cao, Y; Li, LL; Liu, YP; Lu, ZX; Luo, W; Tan, YN; Tang, M; Wang, ZL; Zeng, L | 1 |
| Abmayr, SM; Kocherlakota, KS; McDermott, J; Wu, JM | 1 |
| Du, JY; Hsin, CH; Hsu, TC; Huang, CH; Lee, CF; Lee, YJ; Lin, TH; Wu, WJ; Yao, TY | 1 |
| Daudi, A; Ishihama, Y; Mochida, K; Nakagami, H; Shirasu, K; Sugiyama, N; Tomita, M | 1 |
| Helling, S; Kadenbach, B; Marcus, K; Ramzan, R; Rhiel, A; Vogt, S; Wen, L | 1 |
| Ikuta, K; Maki, K | 1 |
| Jackson, SN; Moyer, SC; Woods, AS | 1 |
| Ge, BX; Huang, Z; Yan, DP | 1 |
| Hang, H; He, Y; Zhang, C; Zhang, CX | 1 |
| Bandyopadhyay, SK; de la Motte, CA; Hascall, VC; Hill, DR; Kessler, SP; Strong, SA | 1 |
| Bui, L; Konradsson, P; Magnusson, KE; Vikström, E | 1 |
| Barry, EF; Biggs, L; Felquer, FA; Grimbaldeston, MA; Guthridge, MA; Hoffmann, P; Lopez, AF; Powell, JA; Ramshaw, H; Stomski, FC; Urbani, A; Wilce, MC | 1 |
| Pocsfalvi, G | 1 |
| Hsieh, WK; Lai, CC; Lin, HH | 1 |
| Davies, AM; Gavaldà, N; Gutierrez, H | 1 |
| Ahn, WK; Han, SY; Lee, S; Oh, HB; Park, S; Rhee, BK | 1 |
| Li, T; Liu, D; Wang, Z | 1 |
| Buckley, DA; Lindsay, AJ; McCaffrey, MW; Neubert, TA; Schwertassek, U; Tonks, NK; Xu, CF | 1 |
| Dao-Feng, B; Wei, D; Xin-Long, C; Zhao-Fan, X | 1 |
| Chung, H; Jahng, WJ; Lee, H; Lee, SH | 1 |
| Barone, E; Butterfield, DA; Cenini, G; Cini, C; Di Domenico, F; Mancuso, C; Perluigi, M; Preziosi, P; Sultana, R | 1 |
| Campa, VM; Kypta, RM | 1 |
| Asara, J; Cantley, LC; Chiu, YH; Lee, JY | 1 |
| Neubert, TA; Zhang, G | 1 |
| Becker, LC; Irani, K; Mattagajasingh, I; Mattagajasingh, SN; Yang, XP | 1 |
| Basnet, H; Botuyan, MV; Couch, FJ; Héroux, A; Mer, G; Mohammad, DH; Rosenfeld, MG; Singh, N; Thompson, JR; Wiltshire, TD; Yaffe, MB | 1 |
| Abekhoukh, S; Delabar, JM; Janel, N; Paul, JL; Planque, C; Ripoll, C; Urbaniak, P | 1 |
| Caelles, C; Codina, M; Del Valle-Pérez, B; Duñach, M; García de Herreros, A; McCrea, PD; Miller, RK; Valls, G; Vinyoles, M | 1 |
| Chun, J; Hyun, S; Kang, SS; Kim, YI; Lee, EJ; Shin, SH | 1 |
| Cook, L; Diakonova, M; Hammer, A; Li, Q; Mattingly, RR; Oladimeji, P; Rider, L | 1 |
| Klerman, H; Levine, E; McClendon, CL; Rapp, C | 1 |
| Chandrasekar, J; Silverman, SK | 1 |
| Ormazabal, P; Quest, AF; Romero, C; Vega, M | 1 |
| Broadbent, JR; Cefalo, AD; Welker, DL | 1 |
| Chien, PN; Hwang, HS; Jeon, TJ; Jeong, DG; Kim, DS; Kim, JK; Kim, SJ; Ku, B; Park, H; Park, SY; Ryu, SE; Ryu, SY; Wei, CH | 1 |
| Aerni, HR; Liu, Y; Rinehart, J; Rogulina, S; Steinfeld, JB | 1 |
| Chung, J; Joo, SY; Kang, D; Koo, MY; Lim, JM; Park, J; Rhee, SG; Shim, HB; Shin, SP; Woo, HA | 1 |
| Bardelli, M; Fasler-Kan, E; Gibbs, BF; Prokhorov, A; Rüegg, L; Sumbayev, VV; Varani, L | 1 |
| Besik, V; Breit, A; Glas, E; Gudermann, T; Muehlich, S; Solinski, HJ; Yarwood, SJ | 1 |
| Brass, LF; Jiang, H; Ma, P; Ou, K; Siderovski, DP; Sinnamon, AJ | 1 |
| Holehouse, AS; Naegle, KM | 1 |
| Cao, R; Li, X; Liang, J; Lu, Z; Wang, L; Xia, Y; Yang, W; Zhang, Y; Zheng, Y | 1 |
| Brázda, V; Dubový, P; Hradilová-Svíženská, I; Joukal, M; Klusáková, I; Kokošová, V | 1 |
| Hong, DK; Jang, I; Jeon, A; Jo, JH; Kim, MS; Lee, ST; Lim, SG; Moon, B; Oh, HB | 1 |
| Chen-Scarabelli, C; Corsetti, G; Dioguardi, FS; Faggian, G; Fanzani, A; Knight, R; Linardi, D; Onorati, F; Pasini, E; Patel, H; Romano, C; Saravolatz, L; Scarabelli, TM; Yuan, Z | 1 |
| Tang, DD; Wang, R; Wang, Y | 1 |
| Dal Piaz, F; Girella, A; Hochkoeppler, A; Stefan, A | 1 |
| Arrieta, AJ; Ayala-Marin, YM; Estrada, A; Grant, AH; Kirken, RA; Rodriguez, AC; Rodriguez, G | 1 |
| Bőhmová, M; Gybeľ, T; Pacherník, J; Radaszkiewicz, KA; Radaszkiewicz, TW; Sladeček, S | 1 |
9 review(s) available for phosphotyrosine and phosphoserine
| Article | Year |
|---|---|
After insulin binds.
Topics: DNA; Drosophila; ErbB Receptors; Humans; Insulin; Molecular Weight; Oncogenes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Cell Surface; Substrate Specificity; Tyrosine | 1987 |
Phosphotyrosyl-protein phosphatases.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Cell Transformation, Viral; Oncogenes; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Retroviridae; Tyrosine | 1983 |
Strategies for nonradioactive methods in the localization of phosphorylated amino acids in proteins.
Topics: Amino Acid Sequence; Amino Acids; Mass Spectrometry; Molecular Sequence Data; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1993 |
Chemical synthesis and applications of phosphopeptides.
Topics: Amino Acid Sequence; Animals; Antibodies; Antigens; Models, Molecular; Molecular Sequence Data; Organophosphonates; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Structure, Secondary; src Homology Domains; Substrate Specificity; Thermodynamics | 1996 |
Signaling through scaffold, anchoring, and adaptor proteins.
Topics: Amino Acid Sequence; Animals; Ligands; Phospholipids; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Signal Transduction; src Homology Domains | 1997 |
Protein phosphorylation: technologies for the identification of phosphoamino acids.
Topics: Animals; Humans; Phosphoamino Acids; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1998 |
Serine phosphorylation of STATs.
Topics: Amino Acid Sequence; Animals; Cell Nucleus; Conserved Sequence; DNA-Binding Proteins; Humans; MAP Kinase Signaling System; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; STAT1 Transcription Factor; Trans-Activators; Transcriptional Activation | 2000 |
Structural and functional hot spots in cytokine receptors.
Topics: Amino Acid Motifs; Animals; Cell Division; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Interleukin-5; Ligands; Models, Molecular; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Conformation; Protein Processing, Post-Translational; Receptors, Cytokine; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin; Receptors, Interleukin-3; Receptors, Interleukin-5; Signal Transduction; Structure-Activity Relationship | 2001 |
Lessons from nature: On the molecular recognition elements of the phosphoprotein binding-domains.
Topics: Binding Sites; Chromatography, Affinity; Crystallography, X-Ray; Humans; Hydrogen Bonding; Imaging, Three-Dimensional; Models, Molecular; Molecular Structure; Phosphates; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Proteome; src Homology Domains; Structure-Activity Relationship | 2005 |
339 other study(ies) available for phosphotyrosine and phosphoserine
| Article | Year |
|---|---|
Cross-talk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of beta 2-adrenergic receptors in response to insulin.
Topics: Animals; Cell Line; Cricetinae; GTP-Binding Proteins; Insulin; Iodine Radioisotopes; Isoproterenol; Kinetics; Male; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Adrenergic, beta; Tyrosine; Vas Deferens | 1992 |
Expression cloning of a human dual-specificity phosphatase.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Gene Expression; Humans; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphoserine; Phosphotyrosine; Restriction Mapping; RNA, Messenger; Sequence Alignment; Substrate Specificity; Tyrosine | 1992 |
Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Kinetics; Muromonab-CD3; Peptide Mapping; Phosphates; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases; Tyrosine | 1992 |
Insulin stimulates the tyrosine phosphorylation of a 61-kilodalton protein in rat adipocytes.
Topics: Adipose Tissue; Animals; Cell Fractionation; Immunoblotting; Insulin; Male; Molecular Weight; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine | 1992 |
p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15.
Topics: CDC2 Protein Kinase; Cell Cycle Proteins; In Vitro Techniques; Nuclear Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Substrate Specificity; Tyrosine | 1992 |
Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase.
Topics: Animals; Cells, Cultured; Enzyme Activation; In Vitro Techniques; Moths; Oncogene Protein pp60(v-src); Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Tyrosine | 1992 |
Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Compartmentation; Cell Membrane; Cloning, Molecular; Cytoplasm; DNA; Gene Expression; In Vitro Techniques; Mice; Molecular Sequence Data; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; RNA, Messenger; Sequence Alignment; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1992 |
Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor.
Topics: Amino Acid Sequence; Humans; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Time Factors; Tyrosine | 1992 |
Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product.
Topics: Amino Acid Sequence; Animals; Enzyme Activation; Fungal Proteins; Genes; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Recombinant Proteins; Sequence Alignment; Tyrosine | 1992 |
Tyrosine-protein kinase inhibition in human erythrocytes by polyphosphoinositides (PIP and PIP2).
Topics: Adenosine Triphosphate; Anion Exchange Protein 1, Erythrocyte; Chymotrypsin; Erythrocytes; Humans; Hydrogen-Ion Concentration; Peptide Fragments; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1992 |
Dissociation of human cytokine receptor expression and signal transduction.
Topics: Cell Division; Dimethyl Sulfoxide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-3; Signal Transduction; Tretinoin; Tumor Cells, Cultured; Tyrosine | 1992 |
Okadaic acid and vanadate inhibit collagen-induced platelet aggregation; the functional relation of phosphatases on platelet aggregation.
Topics: Adenosine Triphosphate; Blood Platelets; Collagen; Depression, Chemical; Ethers, Cyclic; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Phosphatase 1; Serotonin; Tyrosine; Vanadates | 1992 |
Interleukin-2 signal transduction in human NK cells: multisite phosphorylation and activation of the tyrosine kinase p56lck.
Topics: Cells, Cultured; Enzyme Activation; Humans; In Vitro Techniques; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1992 |
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 1990 |
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody.
Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
Determination of dityrosine, phosphotyrosine, phosphothreonine, and phosphoserine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Microchemistry; p-Dimethylaminoazobenzene; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Serine; Threonine; Tyrosine | 1990 |
Insulin and epidermal growth factor stimulate phosphorylation of p185HER-2 in the breast carcinoma cell line, BT474.
Topics: Blood; Breast Neoplasms; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, ErbB-2; Tumor Cells, Cultured; Tyrosine | 1990 |
Vasopressin dependent tyrosine phosphorylation of a 38 kDa protein in human platelets.
Topics: Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Platelets; Blotting, Western; Colforsin; Dose-Response Relationship, Drug; Electrophoresis; Humans; In Vitro Techniques; Phorbol Esters; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Vasopressin; Time Factors; Tyrosine | 1990 |
Occurrence of protein phosphorylation in various bacterial species.
Topics: Adenosine Triphosphate; Arthrobacter; Bacillus; Bacillus megaterium; Bacteria; Bacterial Proteins; Cyclic AMP; Cyclic GMP; Escherichia coli; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Pseudomonas; Tyrosine | 1990 |
Examination of the role of serine phosphorylation in phospholipase C-gamma and its related P47 in cAMP-mediated depression of epidermal growth factor signal transduction.
Topics: Colforsin; Cross Reactions; Epidermal Growth Factor; ErbB Receptors; Humans; In Vitro Techniques; Molecular Weight; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1990 |
[Phosphoamino acid analysis by 2-dimensional electrophoresis].
Topics: Electrophoresis, Gel, Two-Dimensional; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1990 |
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product.
Topics: Amino Acid Sequence; Animals; In Vitro Techniques; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Molecular Sequence Data; Oligopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptor, Macrophage Colony-Stimulating Factor; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Temperature; Tyrosine | 1990 |
Signal transduction of human interleukin 3 and granulocyte-macrophage colony-stimulating factor through serine and tyrosine phosphorylation.
Topics: Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Isoenzymes; Kinetics; Phosphates; Phosphoserine; Phosphotyrosine; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
Interleukin-3 and granulocyte-macrophage colony-stimulating factor mediate rapid phosphorylation and activation of cytosolic c-raf.
Topics: Animals; Cell Line; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Immunosorbent Techniques; Interleukin-3; Kinetics; Mice; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Tyrosine | 1990 |
Basic polycations activate the insulin receptor kinase and a tightly associated serine kinase.
Topics: Animals; Cattle; Cell Membrane; Enzyme Activation; In Vitro Techniques; Liver; Macromolecular Substances; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Polyamines; Polyelectrolytes; Polylysine; Polymers; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Rod Cell Outer Segment; Tyrosine | 1990 |
MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways.
Topics: Adipose Tissue; Animals; Blood; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Reactivators; Epidermal Growth Factor; Fibroblasts; Insulin; Mice; Oocytes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Tyrosine; Xenopus | 1991 |
Nerve growth factor stimulates phosphorylation of phospholipase C-gamma in PC12 cells.
Topics: Animals; Blotting, Western; Cells, Cultured; Epidermal Growth Factor; In Vitro Techniques; Isoenzymes; Nerve Growth Factors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Type C Phospholipases; Tyrosine | 1991 |
Two-dimensional phosphopeptide analysis of the autophosphorylation cascade of a soluble insulin receptor tyrosine kinase. The tyrosines phosphorylated are typical of those observed following phosphorylation of the heterotetrameric insulin receptor in inta
Topics: Amino Acid Sequence; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptide Mapping; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Trypsin; Tyrosine | 1991 |
The tumor suppressor p53 is bound to RNA by a stable covalent linkage.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Genes, Tumor Suppressor; Mice; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphotyrosine; Rats; Ribonucleoproteins; RNA; Tumor Suppressor Protein p53; Tyrosine | 1991 |
An alternative method for a fast separation of phosphotyrosine.
Topics: Adenosine Triphosphate; Animals; Chromatography, Thin Layer; Cytidine Monophosphate; Humans; Liver; Lymphocytes; Mice; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine; Uridine Monophosphate | 1990 |
Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase.
Topics: Amino Acid Sequence; Animals; Casein Kinases; Cell Division; Cytosol; Kinetics; Liver; Molecular Sequence Data; Oligopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Substrate Specificity; Tyrosine | 1991 |
Phosphorylation sites of the nicotinic acetylcholine receptor. A novel site detected in position delta S362.
Topics: Animals; Chromatography, High Pressure Liquid; Enzyme Activation; Phosphates; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Receptors, Nicotinic; Torpedo; Tyrosine | 1991 |
Analysis of insulin receptor phosphorylation sites in intact rat liver cells by two-dimensional phosphopeptide mapping. Predominance of the tris-phosphorylated form of the kinase domain after stimulation by insulin.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Insulin; Liver; Male; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine | 1991 |
Elongation factor-2 in chick embryo is phosphorylated on tyrosine as well as serine and threonine.
Topics: Age Factors; Animals; Chick Embryo; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Subcellular Fractions; Tyrosine | 1991 |
Heparin stimulates epidermal growth factor receptor-mediated phosphorylation of tyrosine and threonine residues.
Topics: Amino Acids; Animals; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Escherichia coli; Glutathione Transferase; Heparin; Humans; Insecta; Manganese; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine | 1991 |
Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Enzyme Activation; Insulin; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Recombinant Proteins; Sequence Homology, Nucleic Acid; Tyrosine | 1991 |
Recombinant human pim-1 protein exhibits serine/threonine kinase activity.
Topics: Cloning, Molecular; DNA; Escherichia coli; Humans; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Recombinant Proteins; Substrate Specificity; Tyrosine | 1991 |
Distribution and contents of free O-phosphoamino acids in animal tissues.
Topics: Animals; Brain Chemistry; Chickens; Chromatography, Gas; Fishes; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Myocardium; Organ Specificity; Phosphoserine; Phosphothreonine; Phosphotyrosine; Species Specificity; Swine; Tyrosine | 1991 |
Measurement of picomoles of phosphoamino acids by high-performance liquid chromatography.
Topics: Amino Acids; Caseins; Chromatography, High Pressure Liquid; Organophosphorus Compounds; Phosphoserine; Phosphothreonine; Phosphotyrosine; Reproducibility of Results; Serum Albumin, Bovine; Tyrosine | 1991 |
Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Antigens, CD; Enzyme Activation; Histocompatibility Antigens; In Vitro Techniques; Leukocyte Common Antigens; Nerve Growth Factors; Neurons; Pheochromocytoma; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Rats; Receptor, trkA; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1991 |
Insulin-induced stimulation of protein phosphorylation in Neurospora crassa cells.
Topics: Antibodies; Autoradiography; Fungal Proteins; Immunosorbent Techniques; Insulin; Membrane Proteins; Neurospora crassa; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphotyrosine; Receptor, Insulin; Tyrosine | 1991 |
Determination of phosphoamino acid composition by acid hydrolysis of protein blotted to Immobilon.
Topics: Amino Acids; Chromatography, Gel; Hydrolysis; Membranes, Artificial; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphotyrosine; Polyvinyls; Radioisotope Dilution Technique; Sulfur Radioisotopes; Tyrosine | 1991 |
Separation of phosphotyrosine, phosphoserine, and phosphothreonine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1991 |
Purification of mitogen-activated protein kinase from epidermal growth factor-treated 3T3-L1 fibroblasts.
Topics: 3T3 Cells; Animals; Autoradiography; Buffers; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Indicators and Reagents; Kinetics; Mice; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1991 |
Demonstration of separate phosphotyrosyl- and phosphoseryl- histone phosphatase activities in the plasma membranes of a human astrocytoma.
Topics: 4-Nitrophenylphosphatase; Astrocytoma; Cell Line; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Diphosphates; Histones; Humans; Hydrolysis; In Vitro Techniques; Nitrophenols; Nucleotides; Organophosphorus Compounds; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Tissue Distribution; Tyrosine; Vanadates; Vanadium | 1985 |
Epidermal growth factor stimulates the phosphorylation of the calcium-dependent 35,000-dalton substrate in intact A-431 cells.
Topics: Animals; Autoradiography; Calcium; Cell Line; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Mice; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proteins; Time Factors; Tyrosine | 1985 |
A simple and rapid method of quantitative analysis of phosphoamino acids by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1985 |
Biochemical characterization of two Epstein-Barr virus early antigen-associated phosphopolypeptides.
Topics: Antibodies, Monoclonal; Antigens, Viral; Cell Line; Chromatin; DNA; DNA-Binding Proteins; Herpesvirus 4, Human; Humans; Molecular Weight; Phosphopeptides; Phosphoserine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Tyrosine; Viral Proteins | 1985 |
Rapid separation of phosphoamino acids including the phosphohistidines by isocratic high-performance liquid chromatography of the orthophthalaldehyde derivatives.
Topics: Aldehydes; Amino Acids; Arginine; Buffers; Chromatography, High Pressure Liquid; Histidine; o-Phthalaldehyde; Organophosphorus Compounds; Phosphoserine; Phosphothreonine; Phosphotyrosine; Temperature; Tyrosine | 1985 |
Calcineurin-mediated dephosphorylation of the human placental membrane receptor for epidermal growth factor urogastrone.
Topics: Brain; Calmodulin-Binding Proteins; Cations, Monovalent; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Kinetics; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Pregnancy; Receptors, Cell Surface; Tyrosine | 1985 |
Phosphorylation of proteins in Clostridium thermohydrosulfuricum.
Topics: Bacterial Proteins; Calmodulin; Cell-Free System; Clostridium; Hexosephosphates; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyamines; Subcellular Fractions; Tyrosine | 1986 |
The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.
Topics: Animals; Carrier Proteins; Cell Line; Cytoskeletal Proteins; Fluorescent Antibody Technique; Humans; Isoelectric Point; Microfilament Proteins; Microvilli; Molecular Weight; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Subcellular Fractions; Tissue Distribution; Tyrosine | 1986 |
Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Cell Line; Colforsin; Cyclic AMP; Lymphocytes; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Receptor, Insulin; Time Factors; Tyrosine | 1986 |
Tumor promoters cause changes in the state of phosphorylation and apparent molecular weight of a tyrosine protein kinase in T lymphocytes.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Immunologic Techniques; Immunosorbent Techniques; Lymphoma; Mice; Molecular Weight; Phorbols; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Phosphotyrosine-containing 120,000-dalton protein coimmunoprecipitated with pp60v-src from Rous sarcoma virus-transformed mammalian cells.
Topics: Animals; Arvicolinae; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Chemical Precipitation; Chick Embryo; Epitopes; Immune Sera; Mice; Molecular Weight; Muscle Proteins; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Retroviridae Proteins; Tyrosine; Vinculin | 1986 |
Characterization of the monomeric and complex-associated forms of the gag-onc fusion proteins of three isolates of feline sarcoma virus: phosphorylation, kinase activity, acylation, and kinetics of complex formation.
Topics: Acylation; Animals; Cats; Cells, Cultured; Fibroblasts; Gene Products, gag; Kinetics; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae; Retroviridae Proteins; Sarcoma Viruses, Feline; Tyrosine | 1986 |
Characterization of the phosphorylatable myosin light chain in rat uterus.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Female; Isoelectric Point; Molecular Weight; Myosins; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Tyrosine; Uterus | 1986 |
Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chickens; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Retroviridae Proteins; Species Specificity; Tyrosine; Vanadium | 1986 |
Epidermal growth factor receptor kinase translocation and activation in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Golgi Apparatus; Kinetics; Liver; Male; Microscopy, Electron; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Tyrosine | 1986 |
Characterization of the phosphotyrosyl protein phosphatase activity of calmodulin-dependent protein phosphatase.
Topics: Amino Acid Sequence; Animals; Brain; Calmodulin; Cattle; Fluorides; Kinetics; Manganese; Myocardium; Myosins; Nickel; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Serine; Tyrosine; Vanadates; Vanadium; Zinc | 1986 |
Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor.
Topics: Animals; Antigens; Isoelectric Point; Lymphocyte Activation; Macromolecular Substances; Membrane Proteins; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Distinct specificities of repressible acid phosphatase from yeast toward phosphoseryl and phosphotyrosyl phosphopeptides.
Topics: Acid Phosphatase; Amino Acid Sequence; Isoenzymes; Kinetics; Phosphoproteins; Phosphoserine; Phosphotyrosine; Saccharomyces cerevisiae; Substrate Specificity; Tyrosine | 1986 |
Resolution and identification of O-phosphoserine, O-phosphothreonine, O-phosphotyrosine, and gamma-carboxyglutamic acid as their fluorescent o-phthalaldehyde derivatives by high performance liquid chromatography.
Topics: 1-Carboxyglutamic Acid; Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; o-Phthalaldehyde; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1986 |
gp140v-fms molecules expressed at the surface of cells transformed by the McDonough strain of feline sarcoma virus are phosphorylated in tyrosine and serine.
Topics: Animals; Cats; Cell Transformation, Neoplastic; Genes; Genes, Viral; Oncogene Protein gp140(v-fms); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Retroviridae; Retroviridae Proteins; Serine; Tyrosine; Vanadates; Vanadium | 1986 |
Separation and quantitative analysis of O-linked phosphoamino acids by isocratic high-performance liquid chromatography of the 9-fluorenylmethyl chloroformate derivatives.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Fluorenes; Ion Exchange Resins; Organophosphorus Compounds; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1986 |
Histone phosphorylation in explants of mouse mammary glands and tumors.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Histones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1986 |
Forms of pp60v-src isolated from Rous sarcoma virus-transformed cells.
Topics: Animals; Antibodies, Monoclonal; Arvicolinae; Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine; Vanadium | 1987 |
Epidermal growth factor stimulates serine and tyrosine phosphorylation in a 59-kD protein in purified plasma membranes from rat liver.
Topics: Animals; Endopeptidases; Epidermal Growth Factor; Liver; Male; Membrane Proteins; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Inbred Strains; Serine; Serine Endopeptidases; Tyrosine | 1987 |
Characterization of phosphate residues on thyroglobulin.
Topics: Animals; Carbohydrates; Cattle; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Mannose; Methionine; Phosphates; Phosphoserine; Phosphotyrosine; Pronase; Rats; Rats, Inbred F344; Thyroglobulin; Thyroid Gland; Tunicamycin; Tyrosine | 1987 |
Alteration of protein phosphorylation patterns in cell lines morphologically transformed by human cytomegalovirus.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cytomegalovirus; Humans; Isoelectric Point; Membrane Proteins; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Spermidine; Tyrosine | 1987 |
Phosphorylation of the lysosomal enzyme binding receptor protein from monkey brain and evidence for a tyrosine kinase activity associated with it.
Topics: Animals; Brain; Carrier Proteins; Histones; Intracellular Membranes; Lysosomes; Membrane Proteins; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, IGF Type 2; Tyrosine | 1987 |
gp140, the EBV/C3d receptor (CR2) of human B lymphocytes, is involved in cell-free phosphorylation of p120, a nuclear ribonucleoprotein.
Topics: B-Lymphocytes; Cell Nucleus; Herpesvirus 4, Human; Humans; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Precursors; Receptors, Complement; Receptors, Complement 3d; Receptors, Virus; Ribonucleoproteins; Tumor Cells, Cultured; Tyrosine | 1987 |
The stereospecificity of protein kinases.
Topics: Blood Proteins; Erythrocytes; Humans; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Stereoisomerism; Substrate Specificity; Tyrosine | 1987 |
Secretion of high and low molecular weight phosphorylated apolipoprotein B by hepatocytes from control and diabetic rats. Phosphorylation of APO BH and APO BL.
Topics: Animals; Apolipoproteins B; Cells, Cultured; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Liver; Male; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.
Topics: Animals; Cell Line; Immunoassay; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1988 |
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Electrophoresis, Polyacrylamide Gel; HIV; Humans; Hydrogen-Ion Concentration; Immunosorbent Techniques; Lymphocyte Activation; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Virus; T-Lymphocytes; Tyrosine | 1988 |
Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.
Topics: Adenosine Triphosphate; Adipose Tissue; Arsenicals; Cell Line; Deoxyglucose; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Insulin; Kinetics; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Trypsin; Tyrosine; Vanadates | 1988 |
Determination of [32P]phosphoamino acids in protein hydrolysates by isocratic anion-exchange high-performance liquid chromatography.
Topics: Buffers; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Serine; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1988 |
Regulation by the autophosphorylation site in overexpressed pp60c-src.
Topics: Animals; Mice; Mutation; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Structure-Activity Relationship; Tyrosine; Vanadium | 1988 |
Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Immunosorbent Techniques; Kinetics; Oncogene Protein pp60(v-src); Phosphoenolpyruvate; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Pyruvate Kinase; Retroviridae Proteins; Tyrosine | 1988 |
Characterization of sites of serine phosphorylation in human placental insulin receptor copurified with insulin-stimulated serine kinase activity by two-dimensional thin-layer peptide mapping.
Topics: Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Insulin; Serine; Tyrosine | 1989 |
Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria.
Topics: Electrophoresis, Gel, Two-Dimensional; Escherichia coli; Glutamate-Ammonia Ligase; Hydrolysis; Molecular Weight; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Radioisotope Dilution Technique; Salmonella typhimurium; Species Specificity; Tyrosine | 1989 |
Serine and tyrosine phosphorylation of 28- and 35-kDa proteins of human T lymphocytes stimulated by streptococcal M protein.
Topics: Antigens, Bacterial; Antigens, Differentiation, T-Lymphocyte; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Humans; Lymphocyte Activation; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Phytohemagglutinins; Serine; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Tyrosine | 1989 |
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro.
Topics: Animals; Blotting, Western; Cell Line; ErbB Receptors; Humans; Mice; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Precipitin Tests; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Time Factors; Type C Phospholipases; Tyrosine | 1989 |
Thin-layer chromatography can resolve phosphotyrosine, phosphoserine, and phosphothreonine in a protein hydrolyzate.
Topics: Animals; Autoradiography; Chromatography, Thin Layer; Humans; Hydrolysis; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1989 |
Antibodies and radioimmunoassays for phosphoserine, phosphothreonine and phosphotyrosine. Serologic specificities and levels of the phosphoamino acids in cytoplasmic fractions of rat tissues.
Topics: Animals; Antibodies; Antibody Specificity; Chromatography, Ion Exchange; Cytoplasm; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred F344; Serine; Serum Albumin, Bovine; Threonine; Tyrosine | 1989 |
The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2.
Topics: Antigens, Differentiation, T-Lymphocyte; Blotting, Western; CD2 Antigens; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Weight; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Receptors, Immunologic; T-Lymphocytes; Time Factors; Tyrosine | 1989 |
Characterization of phosphorylated amino acids by fast-atom bombardment mass spectrometry.
Topics: Phosphoserine; Phosphothreonine; Phosphotyrosine; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1989 |
Distribution of phosphoserine, phosphothreonine and phosphotyrosine in proteins of vesicular stomatitis virus.
Topics: Animals; Cells, Cultured; Cricetinae; Kidney; Mesocricetus; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Tyrosine; Vesicular stomatitis Indiana virus; Viral Proteins | 1981 |
Purified low-molecular-weight protein kinase from murine sarcoma virus particles catalyzes tyrosine phosphorylation endogenously but phosphorylates cellular proteins at serine.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Viral; Magnesium; Mice; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proteins; Sarcoma Viruses, Murine; Serine; Tyrosine | 1981 |
Phosphorylation and metabolism of the transforming protein of Rous sarcoma virus.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1982 |
Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.
Topics: Amino Acids; Animals; Insulin; Liver Neoplasms, Experimental; Macromolecular Substances; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptor, Insulin; Serine; Tyrosine | 1982 |
The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins.
Topics: Alpharetrovirus; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Chick Embryo; Molecular Weight; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins | 1982 |
Separation of phosphohydroxyamino acids by high-performance liquid chromatography.
Topics: Animals; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic AMP; Hydrolysis; Myelin Basic Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Serine; Threonine; Tyrosine | 1982 |
Two-dimensional separation of phosphoamino acids from nucleoside monophosphates.
Topics: Adenosine Monophosphate; Chromatography, Thin Layer; Cytidine Monophosphate; Electrophoresis; Escherichia coli; Guanosine Monophosphate; Nucleotides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Thymidine Monophosphate; Tyrosine; Uracil Nucleotides; Uridine Monophosphate | 1982 |
An acid phosphatase in the plasma membranes of human astrocytoma showing marked specificity toward phosphotyrosine protein.
Topics: Acid Phosphatase; Astrocytoma; Cell Line; Cell Membrane; Humans; Hydrogen-Ion Concentration; Neoplasms, Experimental; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphotyrosine; Substrate Specificity; Tyrosine | 1982 |
Dansylation and high-performance liquid chromatographic separation of phosphoserine, phosphothreonine and phosphotyrosine from 32P-labeled protein hydrolyzates.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Dansyl Compounds; Hydrolysis; In Vitro Techniques; Isotope Labeling; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Rats; Serine; Threonine; Tyrosine | 1982 |
A rapid microdetermination of phosphoserine, phosphothreonine, and phosphotyrosine in proteins by automatic cation exchange on a conventional amino acid analyzer.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Myocardium; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1983 |
The association of the transforming protein of Rous sarcoma virus with two cellular phosphoproteins.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chickens; Macromolecular Substances; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1983 |
Polyamide thin-layer chromatography of phosphorylated tyrosine, threonine, and serine.
Topics: Chromatography, Thin Layer; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1983 |
Appearance of functional EGF receptor kinase during rodent embryogenesis.
Topics: Age Factors; Animals; ErbB Receptors; Liver; Mice; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Rats; Tyrosine | 1983 |
Measurement of chemical phosphate in proteins.
Topics: Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphotyrosine; Proteins; Radioisotope Dilution Technique; Serine; Tyrosine | 1983 |
Two different protein kinase activities are associated with the insulin receptor.
Topics: Animals; Caseins; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Histones; In Vitro Techniques; Isoenzymes; Liver; Male; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine | 1983 |
Functional studies on the Rous sarcoma virus transforming gene product.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1984 |
Tyrosine protein kinase activity in normal rat tissues: brain.
Topics: Animals; Binding Sites; Brain; Cations, Divalent; Male; Nerve Tissue Proteins; Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Rats; Structure-Activity Relationship; Tyrosine | 1984 |
Calmodulin-stimulated phosphorylation of 17 beta-estradiol receptor on tyrosine.
Topics: Animals; Calmodulin; Cattle; Cell Nucleus; Cytosol; Enzyme Activation; Estradiol; Female; Kinetics; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Receptors, Estradiol; Receptors, Estrogen; Tyrosine; Uterus | 1984 |
Chemical properties, isolation, and analysis of O-phosphates in proteins.
Topics: Carbon Radioisotopes; Chemical Phenomena; Chemistry; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tritium; Tyrosine | 1984 |
Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptors.
Topics: Amino Acids; Animals; Cell Differentiation; Cell Division; Cell Line; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Macromolecular Substances; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptor Protein-Tyrosine Kinases; Receptors, Granulocyte Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Proteins; Transfection; Tyrosine | 1993 |
Synergistic control mechanism for abnormal site phosphorylation of Alzheimer's diseased brain tau by kinase FA/GSK-3 alpha.
Topics: Alzheimer Disease; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Glycogen Synthase Kinase 3; Humans; Kinetics; Microtubule-Associated Proteins; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Substrate Specificity; tau Proteins; Tyrosine | 1993 |
GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Dogs; ErbB Receptors; Erythrocytes; G(M3) Ganglioside; Humans; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Tumor Cells, Cultured; Tyrosine | 1994 |
Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B).
Topics: Amino Acid Sequence; Angiotensin II; Animals; Calcineurin; Calmodulin-Binding Proteins; Casein Kinases; Kinetics; Liver; Molecular Sequence Data; Phosphopeptides; Phosphoprotein Phosphatases; Phosphoserine; Phosphotyrosine; Protein Kinases; Rats; Substrate Specificity; Tyrosine | 1994 |
Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase.
Topics: 3-O-Methylglucose; Animals; Cell Line; Fibroblasts; Glucose; Humans; Insulin; Isoenzymes; Kinetics; Mannitol; Methylglucosides; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Rats; Receptor, Insulin; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1994 |
Multiple sites of phosphorylation within the alpha heavy chain of Chlamydomonas outer arm dynein.
Topics: Animals; Centrifugation, Density Gradient; Chlamydomonas; Dyneins; Flagella; Pancreatic Elastase; Peptide Fragments; Phosphates; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Trypsin; Tyrosine | 1994 |
Protein kinase C-dependent phosphorylation of a ciliary membrane protein and inhibition of ciliary beating.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Annexins; Carbazoles; Cell Fractionation; Cilia; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Erythrocytes; Indoles; Isoquinolines; Membrane Proteins; Movement; Phosphorylation; Phosphoserine; Phosphotyrosine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sheep; Tetradecanoylphorbol Acetate; Trachea; Tyrosine | 1993 |
Tyrosine and serine phosphorylation of dystrophin and the 58-kDa protein in the postsynaptic membrane of Torpedo electric organ.
Topics: Adenosine Triphosphate; Animals; Cell Fractionation; Centrifugation, Density Gradient; Dystrophin; Electric Organ; Electrophoresis, Polyacrylamide Gel; Membrane Proteins; Molecular Weight; Phosphoserine; Phosphotyrosine; Synaptic Membranes; Torpedo; Tyrosine | 1994 |
The angiotensin II AT1 receptor is tyrosine and serine phosphorylated and can serve as a substrate for the src family of tyrosine kinases.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Cloning, Molecular; Genes, src; Glutathione Transferase; Isoenzymes; Kinetics; Muscle, Smooth, Vascular; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Angiotensin; Recombinant Fusion Proteins; Substrate Specificity; Type C Phospholipases; Tyrosine | 1994 |
Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx.
Topics: Aluminum Compounds; Calcium; CD3 Complex; Cell Line; Cytokines; Fluorides; Glutathione; Humans; In Vitro Techniques; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Terpenes; Thapsigargin; Tyrosine | 1994 |
Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung.
Topics: Adenocarcinoma; Amino Acid Sequence; Antibodies; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Casein Kinases; Caseins; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Kinetics; Lung; Lung Neoplasms; Molecular Sequence Data; Myelin Basic Protein; Peptides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Proteins; Substrate Specificity; Tyrosine | 1994 |
Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycogen Synthase Kinases; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Weight; Muscles; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Recombinant Proteins; Tyrosine | 1994 |
Bile acid efflux mediated by the rat liver canalicular bile acid transport/ecto-ATPase protein requires serine 503 phosphorylation and is regulated by tyrosine 488 phosphorylation.
Topics: Adenosine Triphosphatases; Alkaloids; Amino Acid Sequence; Amino Acids; Animals; Antigens, CD; Base Sequence; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cell Adhesion Molecules; Cells, Cultured; Consensus Sequence; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Phorbol Esters; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Rats; Staurosporine; Structure-Activity Relationship; Transfection; Tyrosine | 1994 |
Phosphorylation and identification of a major tyrosine phosphorylation site in protein tyrosine phosphatase 1C.
Topics: Amino Acid Sequence; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; Tyrosine | 1994 |
Protein-tyrosine phosphatase activity of CD45 is activated by sequential phosphorylation by two kinases.
Topics: Animals; Casein Kinase II; Cell Line; Cricetinae; Enzyme Activation; Humans; Leukocyte Common Antigens; Lymphocyte Activation; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; T-Lymphocytes; Time Factors; Tyrosine | 1994 |
Autophosphorylation-activated protein kinase inactivates the protein tyrosine phosphatase activity of protein phosphatase 2A.
Topics: Adenosine Triphosphate; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; ErbB Receptors; Glycogen Synthase Kinase 3; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protamine Kinase; Protein Kinases; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Recombinant Proteins; Substrate Specificity; Tyrosine | 1994 |
Determination of antigen-antibody affinity by immunocapillary electrophoresis.
Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Capillary Action; Electrophoresis; Hydrogen-Ion Concentration; Immunologic Techniques; Kinetics; Phosphoserine; Phosphotyrosine; Tyrosine | 1994 |
Platelet-derived growth factor stimulates phosphorylation of growth factor receptor-binding protein-2 in vascular smooth muscle cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cells, Cultured; ErbB Receptors; GRB2 Adaptor Protein; In Vitro Techniques; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; Rats; Signal Transduction; Tyrosine | 1994 |
Cloning and biochemical characterization of a plant protein kinase that phosphorylates serine, threonine, and tyrosine.
Topics: Arabidopsis; Arabidopsis Proteins; Base Sequence; Cloning, Molecular; DNA Primers; Molecular Sequence Data; Phosphoserine; Phosphothreonine; Phosphotyrosine; Plant Proteins; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 1994 |
Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and zeste-white 3 kinase.
Topics: Amino Acid Sequence; Animals; Armadillo Domain Proteins; Cell Adhesion; Consensus Sequence; Drosophila melanogaster; Drosophila Proteins; Glycogen Synthase Kinase 3; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Structure-Activity Relationship; Trans-Activators; Transcription Factors; Tyrosine; Wnt1 Protein | 1994 |
Protein kinase C and insulin receptor beta-subunit serine phosphorylation in cultured foetal rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Enzyme Activation; Glucose; Glycogen; Insulin; Liver; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Rats; Receptor, Insulin; Swine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Induction of serine and threonine protein phosphorylation by endotoxin-associated protein in murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Bacterial Proteins; Dinoprostone; Endotoxins; Female; Ionomycin; Lipid A; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
1H and 31P NMR spectroscopy of phosphorylated model peptides.
Topics: Amino Acid Sequence; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Phosphopeptides; Phosphorus; Phosphoserine; Phosphothreonine; Phosphotyrosine; Structure-Activity Relationship; Tyrosine | 1994 |
Selective phosphoamino acid enrichment by organic solvent fractionation.
Topics: Acetone; Chemical Fractionation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1994 |
Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Macroglobulins; Animals; Base Sequence; DNA; DNA-Binding Proteins; Gene Expression Regulation; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-6; Isoquinolines; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphoserine; Phosphotyrosine; Piperazines; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine | 1995 |
Differential phosphorylation of a 57-KDa protein tyrosine kinase during egg activation.
Topics: Amino Acid Sequence; Animals; Antibodies; Cell Cycle; Electrophoresis, Polyacrylamide Gel; Female; Fertilization; Genes, src; Male; Molecular Sequence Data; Molecular Weight; Oocytes; Peptides; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Sea Urchins; Spermatozoa; Tyrosine | 1995 |
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine | 1995 |
Phosphorylation of dense-plaque proteins talin and paxillin during tracheal smooth muscle contraction.
Topics: Acetylcholine; Animals; Binding Sites; Cytoskeletal Proteins; Dogs; Immunosorbent Techniques; Muscle Contraction; Muscle, Smooth; Paxillin; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Talin; Trachea; Tyrosine; Vinculin | 1995 |
Dual modulation of phosphorylation of a 60 kDa nuclear protein in interferon-alpha treated Daudi cells.
Topics: B-Lymphocytes; Cell Line; Humans; Interferon alpha-2; Interferon-alpha; Molecular Weight; Nuclear Proteins; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tyrosine | 1995 |
In vivo and in vitro serine/threonine phosphorylations of epidermal growth factor receptor upon entry into the cell cycle.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Culture Media, Serum-Free; Electrophoresis, Gel, Two-Dimensional; ErbB Receptors; Flow Cytometry; Glioblastoma; Humans; Interphase; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; S Phase; Tyrosine | 1995 |
Nerve growth factor stimulates tyrosine phosphorylation of paxillin in PC12h cells.
Topics: Animals; Blotting, Western; Cell Adhesion Molecules; Cytochalasin D; Cytoskeletal Proteins; Immunosorbent Techniques; Kinetics; Nerve Growth Factors; Paxillin; PC12 Cells; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Signal Transduction; Tyrosine | 1995 |
Phosphatase resistance of ERK2 brain kinase PK40erk2.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Amino Acid Sequence; Animals; Brain; Cattle; Drug Resistance; Enzyme Activation; Isoenzymes; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Phosphates; Phosphoprotein Phosphatases; Phosphoserine; Phosphotyrosine; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Tyrosine | 1995 |
Tyrosine- versus serine-phosphorylation leads to conformational changes in a synthetic tau peptide.
Topics: Alzheimer Disease; Amino Acid Sequence; Antibodies, Monoclonal; Genes, Synthetic; Humans; Immunodominant Epitopes; Molecular Sequence Data; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Conformation; Protein Processing, Post-Translational; Spectroscopy, Fourier Transform Infrared; tau Proteins; Tyrosine | 1994 |
Phosphorylation of human plasminogen activators and plasminogen.
Topics: Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Humans; Immunoblotting; Melanoma; Phosphorylation; Phosphoserine; Phosphotyrosine; Plasminogen; Plasminogen Activators; Tissue Plasminogen Activator; Tumor Cells, Cultured; Tyrosine; Urokinase-Type Plasminogen Activator | 1995 |
The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane.
Topics: 3T3 Cells; Animals; Base Sequence; Cytoplasm; DNA Primers; Fluorescent Antibody Technique; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatases; Recombinant Proteins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Ganglioside GM1 binds to the Trk protein and regulates receptor function.
Topics: Animals; Cell Differentiation; G(M1) Ganglioside; Kinetics; Nerve Growth Factors; Neurites; Neurofilament Proteins; PC12 Cells; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Tyrosine | 1995 |
A new approach to phosphoserine, phosphothreonine and phosphotyrosine synthons and to thiophospho analogs. Stepwise synthesis of mono- and multiphosphorylated phosphopeptides related to src-protein kinase.
Topics: Amino Acid Sequence; CSK Tyrosine-Protein Kinase; Molecular Sequence Data; Organothiophosphates; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine | 1995 |
In vitro binding and phosphorylation of human immunodeficiency virus type 1 Nef protein by serine/threonine protein kinase.
Topics: Base Sequence; Binding Sites; Cell Line; DNA Primers; Gene Products, nef; Genes, nef; Glutathione Transferase; HIV-1; Humans; Kinetics; Molecular Sequence Data; nef Gene Products, Human Immunodeficiency Virus; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Sequence Deletion; Tyrosine | 1995 |
Analysis of phosphorylhydroxyamino acids present in hydrolyzed cell extracts using dabsyl derivatization.
Topics: Cell Extracts; Chromatography, Thin Layer; Electrophoresis; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; p-Dimethylaminoazobenzene; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Protein-Tyrosine Kinases; Quercetin; Tumor Cells, Cultured; Tyrosine | 1995 |
Studies into the identity of the sites of insulin-stimulated insulin receptor serine phosphorylation. Characterization of synthetic peptide substrates for the insulin-stimulated insulin receptor serine kinase.
Topics: Amino Acid Sequence; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insulin; Molecular Sequence Data; Peptide Mapping; Phosphopeptides; Phosphoserine; Phosphotyrosine; Placenta; Pregnancy; Receptor, Insulin; Serine; Substrate Specificity; Trypsin; Tyrosine | 1995 |
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Chlorocebus aethiops; Conserved Sequence; DNA-Binding Proteins; Gene Expression Regulation; Humans; Luciferases; Mice; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine | 1995 |
Protein phosphorylation on serine, threonine, and tyrosine residues modulates membrane-protein interactions and transcriptional regulation in Salmonella typhimurium.
Topics: Adenosine Triphosphate; Bacterial Proteins; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Bacterial; Magnetic Resonance Spectroscopy; Membrane Proteins; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Kinases; Protein-Tyrosine Kinases; Salmonella typhimurium; Tyrosine | 1995 |
Identification of Lck-binding elements in tip of herpesvirus saimiri.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Chlorocebus aethiops; DNA Primers; Herpesvirus 2, Saimiriine; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Point Mutation; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Spodoptera; Structure-Activity Relationship; Transfection; Tyrosine; Viral Proteins | 1995 |
The phosphoinositide 3-kinase inhibitor wortmannin inhibits CD28-mediated T cell co-stimulation.
Topics: Androstadienes; Animals; CD28 Antigens; Cell Line; CHO Cells; Cricetinae; Enzyme Inhibitors; Humans; Lymphocyte Activation; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; T-Lymphocytes; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1995 |
Effects of cooling temperature on the separation of phosphoamino acids.
Topics: Cold Temperature; Electrophoresis; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1995 |
Possible role of protein kinase C in the regulation of intracellular stability of focal adhesion kinase in mouse 3T3 cells.
Topics: 3T3 Cells; Animals; Benzoquinones; Cell Adhesion; Cell Adhesion Molecules; Cinnamates; Enzyme Inhibitors; Enzyme Stability; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Kinetics; Lactams, Macrocyclic; Mice; Mice, Inbred BALB C; Naphthalenes; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinones; Rifabutin | 1995 |
Endogenous phosphorylation of distinct gamma-aminobutyric acid type A receptor polypeptides by Ser/Thr and Tyr kinase activities associated with the purified receptor.
Topics: Affinity Labels; Animals; Blotting, Western; Cattle; Cell Membrane; Cerebral Cortex; Kinetics; Macromolecular Substances; Muscimol; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, GABA-A; Substrate Specificity; Thermodynamics | 1995 |
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Colforsin; Diacylglycerol Kinase; Epidermal Growth Factor; Epitopes; ErbB Receptors; Escherichia coli; Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1993 |
SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells.
Topics: Animals; Cell Differentiation; Mitogens; Nerve Growth Factors; Neurons; Nuclear Proteins; Oncogene Protein pp60(v-src); Oncogenes; PC12 Cells; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Tyrosine | 1993 |
Negative regulation of the wee1 protein kinase by direct action of the nim1/cdr1 mitotic inducer.
Topics: Animals; Baculoviridae; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Escherichia coli; Fungal Proteins; Moths; Nuclear Proteins; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine | 1993 |
Atrial natriuretic factor stimulates phosphorylation of a 52-kDa calmodulin-binding protein in vascular smooth muscle cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Calmodulin-Binding Proteins; Cells, Cultured; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Endothelins; Male; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Rats, Wistar; Tyrosine | 1993 |
Phosphorylation of recombinant non-NMDA glutamate receptors on serine and tyrosine residues.
Topics: Cell Line; Embryo, Mammalian; Gene Expression; Humans; Immunosorbent Techniques; Kidney; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Glutamate; Recombinant Proteins; Transfection; Tyrosine | 1993 |
Identification of O-phosphoamino acids in urine hydrolysate by gas chromatography-mass spectrometry.
Topics: Amino Acids; Chromatography, DEAE-Cellulose; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Phosphoserine; Phosphothreonine; Phosphotyrosine; Photometry; Tyrosine | 1993 |
Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinases.
Topics: Animals; Cell Transformation, Viral; Chick Embryo; DNA Mutational Analysis; Gene Expression Regulation, Enzymologic; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tyrosine; Urokinase-Type Plasminogen Activator | 1993 |
Distinct beta-subunits are present in hybrid insulin-like-growth-factor-1 receptors in the central nervous system.
Topics: Animals; Brain Chemistry; Insulin-Like Growth Factor I; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphotyrosine; Precipitin Tests; Rats; Receptor, IGF Type 1; Receptor, Insulin; Synaptosomes; Tyrosine | 1993 |
Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo.
Topics: Actin Cytoskeleton; Animals; Cell Compartmentation; Cell Division; Concanavalin A; Cytoskeleton; Dictyostelium; Membrane Proteins; Mutation; Myosins; Octoxynol; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Tyrosine | 1993 |
Phosphorylation of two human neurochordins by mammalian casein kinase 1.
Topics: Adenosine Triphosphate; Adolescent; Autoradiography; Brain; Casein Kinases; Electrophoresis, Polyacrylamide Gel; Female; Humans; Membrane Glycoproteins; Molecular Weight; Nerve Tissue Proteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1993 |
Dynamics of connexin43 phosphorylation in pp60v-src-transformed cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Line, Transformed; Connexin 43; Fibroblasts; Immunosorbent Techniques; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; RNA, Messenger; Transformation, Genetic; Tyrosine | 1993 |
Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR.
Topics: Amino Acid Sequence; Dual-Specificity Phosphatases; Humans; Kinetics; Models, Theoretical; Molecular Sequence Data; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Tyrosine Phosphatases; Substrate Specificity | 1995 |
Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.
Topics: Base Sequence; Cell Compartmentation; Cell Membrane; Cell Nucleus; DNA Primers; DNA, Viral; Gene Products, gag; HeLa Cells; HIV-1; Humans; Molecular Sequence Data; Myristates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Viral Matrix Proteins; Virion; Virus Replication | 1996 |
Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Glutathione Transferase; GTPase-Activating Proteins; HeLa Cells; Homeostasis; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Fragments; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proteins; ras GTPase-Activating Proteins; Recombinant Fusion Proteins; Serine; src Homology Domains; src-Family Kinases; Transfection | 1995 |
Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor.
Topics: Base Sequence; Cell Line; DNA Primers; DNA-Binding Proteins; Humans; Interferon-alpha; Membrane Proteins; Molecular Sequence Data; Nuclear Proteins; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Kinase C; Receptor, Interferon alpha-beta; Receptors, Interferon; Signal Transduction; src Homology Domains; STAT3 Transcription Factor; Trans-Activators | 1996 |
Protein kinase A-catalyzed phosphorylation and its effect on conformation in phytochrome A.
Topics: Acid Phosphatase; Adenoma; Adenosine Triphosphate; Amino Acid Sequence; Animals; Avena; Cattle; Circular Dichroism; Cyclic AMP-Dependent Protein Kinases; Humans; Kinetics; Male; Myocardium; Peptide Fragments; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Phytochrome; Phytochrome A; Prostate; Prostatic Neoplasms; Protein Conformation; Protein Structure, Secondary; Substrate Specificity; Trypsin | 1996 |
Crystal structure of the dual specificity protein phosphatase VHR.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Dual Specificity Phosphatase 3; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Sequence Alignment; Substrate Specificity; Water; Yersinia | 1996 |
Phosphotyrosyl protein phosphatase-like activity of a clonal osteoblastic cell line (MC3T3-E1 cell).
Topics: 3T3 Cells; Animals; Cell Line; Clone Cells; Cyclic AMP; Enzyme Inhibitors; Ethers, Cyclic; Histones; Hydrogen-Ion Concentration; Hydrolysis; Mice; Muramidase; Okadaic Acid; Osteoblasts; Peptides; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Vanadates; Zinc | 1995 |
Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells.
Topics: Androstadienes; Animals; Cell Line; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver Neoplasms, Experimental; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Rats; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1996 |
Paramyosin isoforms of Schistosoma mansoni are phosphorylated and localized in a large variety of muscle types.
Topics: Animals; Antibodies, Helminth; Antibody Specificity; Female; Fixatives; Male; Methanol; Molecular Sequence Data; Muscles; Organometallic Compounds; Phosphorylation; Phosphoserine; Phosphotyrosine; Schistosoma mansoni; Tissue Fixation; Trehalose; Tropomyosin | 1996 |
Presence of phosphorus in Nephila clavipes dragline silk.
Topics: Animals; Biophysical Phenomena; Biophysics; Hydrolysis; Insect Proteins; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphates; Phosphorus; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Processing, Post-Translational; Proteins; Silk; Spiders | 1996 |
N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors.
Topics: Acetylcholine; Animals; Female; GTP-Binding Proteins; Kinetics; Membrane Potentials; Models, Molecular; Molecular Structure; Oocytes; Oscillometry; Palmitates; Patch-Clamp Techniques; Phosphoserine; Phosphotyrosine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Glutamate; Receptors, Lysophosphatidic Acid; Second Messenger Systems; Serotonin; Stereoisomerism; Structure-Activity Relationship; Time Factors; Xenopus laevis | 1996 |
Adducin regulation. Definition of the calmodulin-binding domain and sites of phosphorylation by protein kinases A and C.
Topics: Amino Acid Sequence; Binding Sites; Calmodulin; Calmodulin-Binding Proteins; Chromatography, High Pressure Liquid; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Erythrocytes; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Proteins | 1996 |
Analysis of the phosphoamino acid content of phosphoproteins.
Topics: Amino Acids; Chromatography, Thin Layer; Isotope Labeling; p-Dimethylaminoazobenzene; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1996 |
Characterization of the C-terminal domain of ras-GTPase-activating protein (ras-GAP) as substrate for epidermal growth factor receptor and p60c-src kinase.
Topics: Electrophoresis, Polyacrylamide Gel; Enzyme Activation; ErbB Receptors; GTPase-Activating Proteins; Histones; Humans; Kinetics; Magnesium; Manganese; Ovalbumin; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyglutamic Acid; Polylysine; Proteins; ras GTPase-Activating Proteins; src-Family Kinases; Trypsin; Tumor Cells, Cultured; Tyrosine | 1996 |
Determination of phosphoserine in human pepsinogens.
Topics: Chromatography; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Gastric Juice; Humans; Hydrolysis; Pepsinogens; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1996 |
Studies on an insulin-stimulated insulin receptor serine kinase activity: separation of the kinase activity from the insulin receptor and its reconstitution back to the insulin receptor.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glycogen Synthase Kinase 3; Humans; Insulin; Magnesium; Membrane Proteins; Microtubule-Associated Proteins; Myelin Basic Protein; Peptides; Phosphates; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Substrate Specificity | 1995 |
Tyrosine phosphorylation of myelin protein PO.
Topics: Animals; Hydrolysis; Male; Myelin P0 Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Vanadates | 1996 |
Insulin promotes and cyclic adenosine 3',5'-monophosphate impairs functional insertion of insulin receptors in the plasma membrane of rat adipocytes: evidence for opposing effects of tyrosine and serine/threonine phosphorylation.
Topics: Adipocytes; Affinity Labels; Animals; Cell Membrane; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Histocompatibility Antigens Class I; Immunoblotting; Insulin; Male; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Type C Phospholipases | 1997 |
Inhibitors of lipid phosphatidate receptors: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids.
Topics: Animals; Cell Membrane; Chloride Channels; Electric Conductivity; Female; Oocytes; Palmitates; Phosphoserine; Phosphotyrosine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Recombinant Proteins; Stereoisomerism; Xenopus | 1996 |
Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoprotein.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium-Calmodulin-Dependent Protein Kinases; GRB2 Adaptor Protein; Humans; Isoenzymes; Membrane Proteins; Phospholipase C gamma; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins pp60(c-src); Rats; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Shc Signaling Adaptor Proteins; Signal Transduction; Son of Sevenless Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Transfection; Type C Phospholipases | 1997 |
Are phosphorylated tyrosine residues of certain receptors involved in inducing transitory covalent protein cross-linking?
Topics: Animals; Models, Chemical; Models, Structural; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Receptors, Cell Surface; Receptors, Fc; Signal Transduction; Static Electricity | 1997 |
Hyperphosphorylation of beta-catenin on serine-threonine residues and loss of cell-cell contacts induced by calyculin A and okadaic acid in human epidermal cells.
Topics: Apoptosis; beta Catenin; Calcium; Cell Size; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Epidermal Cells; Epidermis; Humans; Intercellular Junctions; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Protein Phosphatase 1; Trans-Activators | 1997 |
Biochemical evidence that the phosphorylated tyrosines, serines, and threonines on the aggregated high affinity receptor for IgE are in the immunoreceptor tyrosine-based activation motifs.
Topics: Amino Acid Sequence; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Receptor Aggregation; Receptors, IgE; src-Family Kinases | 1997 |
Analysis of sites of protein phosphorylation.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Sequence Analysis | 1997 |
The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.
Topics: Gene Products, gag; Gene Products, nef; HIV-1; Humans; Myristates; nef Gene Products, Human Immunodeficiency Virus; p21-Activated Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Viral Matrix Proteins; Virion | 1997 |
Phosphorylation of tick-borne encephalitis virus NS5 protein.
Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Blotting, Western; Cells, Cultured; DNA-Directed RNA Polymerases; Encephalitis Viruses, Tick-Borne; Female; Kidney; Kinetics; Mice; Mice, Inbred BALB C; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; RNA, Viral; Swine; Viral Nonstructural Proteins | 1997 |
Posttranslational regulation of Lck and a p36-38 protein by activators of protein kinase C: differential effects of the tumor promoter, PMA, and the non-tumor-promoter, bryostatin.
Topics: Adjuvants, Immunologic; Bryostatins; Carcinogens; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Lactones; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrolides; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; src-Family Kinases; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin.
Topics: Animals; Binding Sites; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Chick Embryo; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Fibronectins; Focal Adhesion Protein-Tyrosine Kinases; Glutathione Transferase; Muscle, Smooth; Mutagenesis, Site-Directed; Paxillin; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins | 1997 |
Gene cloning and expression and characterization of a toxin-sensitive protein phosphatase from the methanogenic archaeon Methanosarcina thermophila TM-1.
Topics: Acetates; Amino Acid Sequence; Cloning, Molecular; Gene Expression; Genes, Bacterial; Methanosarcina; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphoserine; Phosphotyrosine; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity | 1997 |
Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.
Topics: B7-1 Antigen; CD28 Antigens; Enzyme Activation; Enzyme Inhibitors; Humans; Jurkat Cells; Ligands; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate | 1997 |
EGF receptor phosphorylation is affected by ionizing radiation.
Topics: Adenosine Triphosphate; Cell Division; Cell Line; Cell Membrane; Cesium Radioisotopes; Dose-Response Relationship, Radiation; Epidermal Growth Factor; ErbB Receptors; Gamma Rays; Humans; Kinetics; Methionine; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1997 |
Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Alanine; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Insulin; Insulin-Like Growth Factor I; Isoenzymes; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Transfection; Tyrosine | 1997 |
B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.
Topics: Antibody Formation; B-Lymphocytes; Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Phosphorylation; Phosphoserine; Phosphotyrosine; Ribosomal Protein S6 Kinases; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 1997 |
Gastrin receptor expression and function during rapid transformation of the enterochromaffin-like cells in an African rodent.
Topics: Animals; Blotting, Western; Cell Transformation, Neoplastic; Enterochromaffin Cells; Female; Gastrins; Gene Expression Regulation, Neoplastic; Histamine H2 Antagonists; Immunohistochemistry; Male; Muridae; Phosphorylation; Phosphoserine; Phosphotyrosine; Polymerase Chain Reaction; Receptors, Cholecystokinin; RNA, Messenger; Stomach Neoplasms; Triazoles | 1997 |
Phosphorylation of Tyr7, Tyr10, and Ser27 of alpha-chain in H+,K(+)-ATPase by intrinsic and extrinsic kinases.
Topics: Animals; Cholic Acids; Detergents; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Serine; Swine; Tyrosine | 1997 |
Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Insulin; Insulin Receptor Substrate Proteins; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphoserine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Receptors, Angiotensin; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Determination of the association constant for slow phosphoserine-anti-phosphoserine interaction kinetics by capillary zone electrophoresis.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Electrophoresis, Capillary; Immunoglobulin G; Kinetics; Mice; Phosphoserine; Phosphotyrosine | 1997 |
Wortmannin-sensitive phosphorylation, translocation, and activation of PLCgamma1, but not PLCgamma2, in antigen-stimulated RBL-2H3 mast cells.
Topics: Androstadienes; Animals; Antigens; Biological Transport; Cell Membrane; Dinitrophenols; Enzyme Activation; Enzyme Inhibitors; Golgi Apparatus; Inositol 1,4,5-Trisphosphate; Isoenzymes; Leukemia, Basophilic, Acute; Mast Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptors, IgE; Serum Albumin, Bovine; Tumor Cells, Cultured; Type C Phospholipases; Wortmannin | 1998 |
Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Compartmentation; Cytosol; Insulin; Insulin Receptor Substrate Proteins; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptor, Insulin; Time Factors | 1998 |
Functional studies of dual-specificity phosphatases.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Dual Specificity Phosphatase 1; Immediate-Early Proteins; Molecular Biology; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Substrate Specificity; Xenopus | 1998 |
14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; Glutathione Transferase; Humans; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Phosphoserine; Phosphotyrosine; Polymerase Chain Reaction; Protein Biosynthesis; Protein Structure, Secondary; Proteins; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Spectrum Analysis; Transfection; Tyrosine 3-Monooxygenase | 1998 |
Role of Cx43 phosphorylation and MAP kinase activation in EGF induced enhancement of cell communication in human kidney epithelial cells.
Topics: Antibodies; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Communication; Cell Line; Connexin 43; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Gap Junctions; Humans; Kidney; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Precipitin Tests; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Identification of phosphoproteins coupled to initiation of motility in live epididymal mouse sperm.
Topics: Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Epididymis; Humans; Male; Mice; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Sperm Capacitation; Sperm Motility; Spermatozoa | 1998 |
Fragmentation of phosphopeptides in an ion trap mass spectrometer.
Topics: Amino Acid Sequence; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1998 |
PhosphoBase, a database of phosphorylation sites: release 2.0.
Topics: Animals; Bacteria; Databases, Factual; Humans; Internet; Kinetics; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Plants; Protein Kinases; Substrate Specificity; Viruses | 1999 |
Insulin receptor substrate-1 and phosphatidylinositol 3-kinase regulate extracellular signal-regulated kinase-dependent and -independent signaling pathways during myogenic differentiation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Line; Chromones; Enzyme Activation; Enzyme Inhibitors; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Signal Transduction | 1998 |
Phosphorylation-dephosphorylation states at different sites affect phosphoprotein phosphatase 1 activity.
Topics: Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Phosphatase 1; src-Family Kinases | 1998 |
Regulation by phosphorylation of the zinc finger protein KRC that binds the kappaB motif and V(D)J recombination signal sequences.
Topics: Amino Acid Sequence; Animals; B-Lymphocytes; CDC2 Protein Kinase; Cell Cycle; Cell Line; Cell Nucleus; DNA Nucleotidyltransferases; DNA-Binding Proteins; ErbB Receptors; Hematopoietic Stem Cells; Mice; Molecular Sequence Data; NF-kappa B; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Kinases; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Sequence Homology, Amino Acid; VDJ Recombinases; Zinc Fingers | 1999 |
alpha-thrombin inhibits interleukin-6-induced Stat3 signaling and gp130 gene expression in primary cultures of human lung fibroblasts.
Topics: Antigens, CD; Blotting, Western; Butadienes; Cells, Cultured; Cytokine Receptor gp130; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gene Expression; Humans; Interleukin-6; Lung; MAP Kinase Kinase 1; Membrane Glycoproteins; Mitogen-Activated Protein Kinase Kinases; Nitriles; Phosphorylation; Phosphoserine; Phosphotyrosine; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Thrombin; Trans-Activators | 1999 |
New clues to how proteins link up to run the cell.
Topics: 14-3-3 Proteins; Amino Acid Sequence; cdc25 Phosphatases; Cell Cycle Proteins; Cell Nucleus; Conserved Sequence; Mitosis; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Proteins; Tyrosine 3-Monooxygenase | 1999 |
Correlations in palmitoylation and multiple phosphorylation of rat bradykinin B2 receptor in Chinese hamster ovary cells.
Topics: Acylation; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Mass Spectrometry; Molecular Sequence Data; Palmitates; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Rats; Receptor, Bradykinin B2; Receptors, Bradykinin; Transfection; Trypsin | 1999 |
Inhibitory effect of regucalcin on Ca2+/calmodulin-dependent protein phosphatase activity in rat brain cytosol.
Topics: Animals; Antibodies, Monoclonal; Biomarkers; Brain; Calbindins; Calcineurin; Calcium; Calcium-Binding Proteins; Calmodulin; Carboxylic Ester Hydrolases; Cytosol; Enzyme Activation; Female; Intracellular Signaling Peptides and Proteins; Liver; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Rats, Wistar; S100 Calcium Binding Protein G; S100 Proteins; Sulfotransferases; Trifluoperazine | 1999 |
Heat-shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Enzyme Activation; Fungal Proteins; Gene Expression Regulation, Fungal; Hot Temperature; Humans; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Phosphatase 2; Protein Phosphatase 2C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Signal Transduction; Stress, Physiological | 1999 |
Alternative procedure for two-dimensional separation of phosphoamino acids.
Topics: Autoradiography; Chromatography, Thin Layer; Ninhydrin; Nucleotide Mapping; Peptide Mapping; Phosphoamino Acids; Phosphopeptides; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine | 1999 |
Insulin and exercise decrease glycogen synthase kinase-3 activity by different mechanisms in rat skeletal muscle.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Kinetics; Male; Muscle, Skeletal; Phosphorylation; Phosphoserine; Phosphotyrosine; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley | 1999 |
H-Ras activation promotes cytoplasmic accumulation and phosphoinositide 3-OH kinase association of beta-catenin in epidermal keratinocytes.
Topics: Adenomatous Polyposis Coli Protein; alpha Catenin; Animals; beta Catenin; Cadherins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Cytoplasm; Cytoskeletal Proteins; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Keratinocytes; Mice; Microinjections; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Trans-Activators | 1999 |
Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells.
Topics: Actins; Antigens, Surface; Carbazoles; Carcinoma, Squamous Cell; Cell Membrane; Cell Size; Chemotaxis; Desmosomes; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Integrin alpha6beta4; Integrins; Keratins; Laminin; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Pseudopodia; Signal Transduction; Tumor Cells, Cultured | 1999 |
Effect of serine and tyrosine phosphorylation on retroviral proteinase substrates.
Topics: Aspartic Acid Endopeptidases; Catalytic Domain; HIV Protease; HIV-1; Models, Molecular; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Processing, Post-Translational; Retroviridae; Substrate Specificity; Vimentin | 1999 |
Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor.
Topics: Cell Line; Dimerization; ErbB Receptors; Humans; Leucine Zippers; Phosphorylation; Phosphoserine; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Transfection; Ubiquitin-Protein Ligases | 1999 |
Interleukin-6 activates signal transducer and activator of transcription and mitogen-activated protein kinase signal transduction pathways and induces de novo protein synthesis in human neuronal cells.
Topics: Animals; Dimerization; DNA-Binding Proteins; Hippocampus; Humans; Interleukin-6; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 1999 |
Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase.
Topics: Amino Acid Substitution; Arginine; Binding, Competitive; Calorimetry; Conserved Sequence; Cysteine; Evolution, Molecular; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphotyrosine; src Homology Domains; src-Family Kinases; Structure-Activity Relationship; Thermodynamics; Titrimetry | 1999 |
Regulation of Jak2 tyrosine kinase by protein kinase C during macrophage differentiation of IL-3-dependent myeloid progenitor cells.
Topics: Animals; Apoptosis; Catalysis; Cell Differentiation; Cell Division; DNA Replication; Enzyme Activation; Enzyme Induction; Interleukin-3; Isoenzymes; Janus Kinase 2; Macrophages; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Activation of Akt during simulated ischemia/reperfusion in cardiac myocytes.
Topics: Androstadienes; Animals; Animals, Newborn; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Genistein; Imidazoles; Kinetics; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Pyridines; Rats; Retroviridae Proteins, Oncogenic; Wortmannin | 2000 |
N-(cyclohexanecarboxyl)-O-phospho-l-serine, a minimal substrate for the dual-specificity protein phosphatase IphP.
Topics: Binding Sites; Cell Cycle Proteins; Cyanobacteria; Cyclohexanes; Dual Specificity Phosphatase 3; Humans; Hydrolysis; Isomerism; Kinetics; Molecular Weight; Multienzyme Complexes; Muramidase; Myelin Basic Protein; Naphthalenes; Organophosphorus Compounds; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity | 2000 |
Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation.
Topics: Animals; beta Catenin; Binding Sites; Cadherins; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Desmoplakins; Embryo, Mammalian; Endothelium, Vascular; gamma Catenin; Humans; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet Endothelial Cell Adhesion Molecule-1; Protein Kinase C; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Umbilical Veins; Yolk Sac | 2000 |
Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residue.
Topics: Amino Acid Sequence; Animals; Cattle; Cyclic AMP-Dependent Protein Kinases; Intracellular Signaling Peptides and Proteins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Myelin Basic Protein; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Substrate Specificity | 2000 |
Nongenomic action of progesterone: activation of Xenopus oocyte phospholipase C through a plasma membrane-associated tyrosine kinase.
Topics: Animals; Calcium; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Female; GTP-Binding Proteins; Insulin; Oocytes; Phosphoserine; Phosphotyrosine; Progesterone; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Type C Phospholipases; Tyrphostins; Xenopus | 2000 |
Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6.
Topics: Acute Disease; Carrier Proteins; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Phosphorylation; Phosphoserine; Phosphotyrosine; Proteins; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Dual effects of PKNalpha and protein kinase C on phosphorylation of tau protein by glycogen synthase kinase-3beta.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Bacterial Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Epitopes; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinases; Rats; Recombinant Fusion Proteins; tau Proteins | 2000 |
Bradykinin activates the Janus-activated kinase/signal transducers and activators of transcription (JAK/STAT) pathway in vascular endothelial cells: localization of JAK/STAT signalling proteins in plasmalemmal caveolae.
Topics: Active Transport, Cell Nucleus; Animals; Aorta; Bradykinin; Cattle; Caveolae; Caveolin 1; Caveolins; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Activation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; Proteins; Receptor, Bradykinin B2; Receptors, Bradykinin; STAT3 Transcription Factor; Trans-Activators | 2000 |
Electron capture dissociation of singly and multiply phosphorylated peptides.
Topics: Amino Acid Sequence; Animals; Caseins; Cattle; Chromatography, Affinity; Fourier Analysis; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphotyrosine | 2000 |
Regulation of STAT3 by direct binding to the Rac1 GTPase.
Topics: Amino Acid Substitution; Animals; Cell Line; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Guanine Nucleotide Exchange Factors; Humans; Janus Kinase 2; Mutation; Neoplasm Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; rac1 GTP-Binding Protein; Rats; Signal Transduction; STAT3 Transcription Factor; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Trans-Activators; Transfection; Two-Hybrid System Techniques | 2000 |
Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Anisomycin; Cell Differentiation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha | 2000 |
TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Lymphokines; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Stress, Mechanical; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Protein kinase C delta regulates neural cell adhesion molecule polysialylation state in the rat brain.
Topics: Animals; Avoidance Learning; Brain; Brain Chemistry; Cell Adhesion; Cell Division; Dentate Gyrus; Environment; Enzyme Activation; Glycosylation; Golgi Apparatus; Hippocampus; Intracellular Membranes; Isoenzymes; Male; Memory; Mental Recall; Mice; Nerve Tissue Proteins; Neural Cell Adhesion Molecule L1; Neural Cell Adhesion Molecules; Neuroblastoma; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Rats; Rats, Wistar; Reaction Time; Sialic Acids; Sialyltransferases; Subcellular Fractions; Tumor Cells, Cultured | 2001 |
Preparation and application of antibodies to phosphoamino acid sequences.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Blotting, Western; COS Cells; Cross Reactions; Fusion Proteins, bcr-abl; Immune Sera; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr; Transfection | 2001 |
Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition.
Topics: Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Catalysis; Crystallography, X-Ray; Dimerization; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Insulin; Models, Molecular; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Signal Transduction; Substrate Specificity | 2001 |
Multiple phosphorylation of membrane-associated calcium-dependent protein serine/threonine kinase in Streptomyces fradiae.
Topics: Autoradiography; Calcium; Cell-Free System; Molecular Weight; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Denaturation; Protein Serine-Threonine Kinases; Streptomyces | 2001 |
Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Islets of Langerhans Transplantation; Male; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Lew; Receptor, Insulin; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2001 |
Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.
Topics: Animals; Base Sequence; beta-Adrenergic Receptor Kinases; Cell Line; Cricetinae; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Fibroblasts; Green Fluorescent Proteins; Humans; Immediate-Early Proteins; Kidney; Kinetics; Luminescent Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Polymerase Chain Reaction; Protein Kinase C; Protein Transport; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 2002 |
Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.
Topics: Adaptor Proteins, Signal Transducing; Adult; Carrier Proteins; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Humans; Leptin; Leukocytes, Mononuclear; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Isoforms; Protein Processing, Post-Translational; Protein Subunits; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA-Binding Proteins | 2001 |
Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1.
Topics: Blotting, Western; Cell Nucleus; DNA-Binding Proteins; HeLa Cells; Humans; Interferon-alpha; Interferon-gamma; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Transport; Sendai virus; STAT1 Transcription Factor; Staurosporine; Trans-Activators; Viral Proteins | 2002 |
Regulation of p73 by c-Abl through the p38 MAP kinase pathway.
Topics: Bone Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Genes, abl; Genes, Tumor Suppressor; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kidney; MAP Kinase Kinase 1; MAP Kinase Kinase 6; MAP Kinase Kinase 7; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multigene Family; Nuclear Proteins; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Proline; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Pyridines; Recombinant Fusion Proteins; src Homology Domains; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Proteins | 2002 |
Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.
Topics: Amino Acid Sequence; Animals; Caseins; Cattle; Chromatography, Affinity; Molecular Sequence Data; Ovalbumin; Phosphopeptides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Sequence Analysis, Protein; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.
Topics: 14-3-3 Proteins; 3T3 Cells; Animals; Biological Transport; Cell Nucleus; COS Cells; Cytoplasm; Cytosol; Enzyme Inhibitors; Epidermal Growth Factor; Fluorescent Antibody Technique; Immunosorbent Techniques; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Mice; Microscopy, Confocal; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase | 2002 |
Antibody-based fluorescence detection of kinase activity on a peptide array.
Topics: Antibodies; Fluorescence; Phosphorylation; Phosphoserine; Phosphotransferases; Phosphotyrosine; Protein Array Analysis; Sensitivity and Specificity; Substrate Specificity; Time Factors | 2002 |
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.
Topics: Adipose Tissue; Animals; Fatty Acids, Nonesterified; Female; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl.
Topics: Animals; Apoptosis; Cell Line; Cell Nucleus; DNA-Binding Proteins; Doxorubicin; Fibroblasts; Fusion Proteins, bcr-abl; Genes, abl; Humans; I-kappa B Proteins; Kidney; Mice; Mice, Knockout; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-abl; Recombinant Fusion Proteins; src Homology Domains; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured | 2002 |
General method for the synthesis of caged phosphopeptides: tools for the exploration of signal transduction pathways.
Topics: Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Photolysis; Signal Transduction | 2002 |
Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants.
Topics: Animals; Carcinoma, Lewis Lung; Cell Movement; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesions; Mice; Neoplasm Proteins; Okadaic Acid; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Phosphatase 2; Protein Processing, Post-Translational | 2002 |
Myelin proteolipid protein, basic protein, the small isoform of myelin-associated glycoprotein, and p42MAPK are associated in the Triton X-100 extract of central nervous system myelin.
Topics: Animals; Blotting, Western; Cattle; Cell Extracts; Central Nervous System; Centrifugation, Density Gradient; Chromatography, Gel; Immunoblotting; Mitogen-Activated Protein Kinase 1; Myelin Basic Protein; Myelin Proteolipid Protein; Myelin-Associated Glycoprotein; Octoxynol; Phosphoserine; Phosphotyrosine; Precipitin Tests; Solubility | 2002 |
The requirement of specific membrane domains for Raf-1 phosphorylation and activation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; DNA, Complementary; Genes, ras; Membrane Microdomains; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Proto-Oncogene Proteins c-raf; Recombinant Proteins; Restriction Mapping; Transfection | 2003 |
Protein phosphatase-2A restricts migration of Lewis lung carcinoma cells by modulating the phosphorylation of focal adhesion proteins.
Topics: Animals; Birds; Blotting, Western; Carcinoma, Lewis Lung; Cell Movement; Cytoskeletal Proteins; Down-Regulation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Genes, src; Humans; Mice; Mutation; Neoplasm Metastasis; Neoplasm Proteins; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Precipitin Tests; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein-Tyrosine Kinases | 2003 |
Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Antibodies, Monoclonal; Antigens, CD; Carrier Proteins; Cytokine Receptor gp130; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Human Growth Hormone; Humans; Immunoblotting; Indoles; Janus Kinase 2; Maleimides; MAP Kinase Kinase 1; Membrane Glycoproteins; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptor, ErbB-2; Recombinant Fusion Proteins; Signal Transduction; Transfection; Ubiquitin-Protein Ligases | 2003 |
An experimental and theoretical study of the 13C and 31P chemical shielding tensors in solid O-phosphorylated amino acids.
Topics: Amino Acids; Carbon Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphorus; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Stereoisomerism | 2003 |
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.
Topics: Biopsy; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hexokinase; Humans; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptor, Insulin; Reference Values; RNA, Messenger; Serine | 2003 |
EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.
Topics: Animals; Cell Division; Cells, Cultured; DNA; DNA-Binding Proteins; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Growth Hormone; Hepatocytes; Male; Milk Proteins; Mitogens; Phosphorylation; Phosphoserine; Phosphotyrosine; Prolactin; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Pyrroles; Rats; Rats, Wistar; STAT5 Transcription Factor; Trans-Activators; Transforming Growth Factor alpha | 2003 |
CRP: Cleavage of Radiolabeled Phosphoproteins.
Topics: Humans; Internet; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Radioactive Tracers; Sequence Analysis, Protein; Software | 2003 |
Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants.
Topics: Animals; Blotting, Western; Carcinoma, Lewis Lung; Cytoskeletal Proteins; Down-Regulation; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Mice; Okadaic Acid; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Precipitin Tests; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Tumor Cells, Cultured | 2003 |
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.
Topics: Amino Acid Sequence; Bacillus subtilis; Base Sequence; Conserved Sequence; DNA Primers; Enzyme Activation; Kinetics; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Uridine Diphosphate Glucose Dehydrogenase | 2003 |
Inhibition of interferon gamma signaling by the short chain fatty acid butyrate.
Topics: Butyrates; Cell Line, Tumor; Cell Nucleus; DNA; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Humans; Interferon-gamma; Janus Kinase 2; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Transport; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Transcription, Genetic; Transfection | 2003 |
Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
Topics: Astrocytoma; Calcium; Carbachol; Cell Line, Tumor; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Receptor Substrate Proteins; Ionomycin; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Muscarinic; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
Topics: Angiotensin II; Cells, Cultured; Codon; Culture Media, Serum-Free; Endothelial Cells; Endothelium, Vascular; Glucose; Humans; Insulin; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Losartan; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Signal Transduction; Umbilical Veins | 2004 |
Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats.
Topics: Animals; Animals, Genetically Modified; Blotting, Western; Calcium; Calcium Chloride; Calcium-Binding Proteins; Calmodulin; Carboxylic Ester Hydrolases; Chelating Agents; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Gene Dosage; Intracellular Signaling Peptides and Proteins; Male; Microsomes, Liver; Okadaic Acid; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfotransferases; Trifluoperazine; Vanadates | 2004 |
Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry.
Topics: Animals; Cattle; Electron Transport Complex I; Female; Fluorescent Dyes; HeLa Cells; Humans; Mitochondria, Heart; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Subunits; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance.
Topics: Adenoviridae; Animals; Binding Sites; Cell Line; Cricetinae; Enzyme Activation; Gene Expression Regulation, Viral; Genes, myc; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine | 2004 |
Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells.
Topics: Apoptosis; Arachidonic Acid; Cell Proliferation; Cell Shape; Cells, Cultured; DNA; DNA Fragmentation; Docosahexaenoic Acids; Endothelial Cells; Enzyme Activation; Humans; Membrane Potentials; Mitochondria; p38 Mitogen-Activated Protein Kinases; Phosphoserine; Phosphotyrosine; Superoxides; Tumor Suppressor Protein p53; Umbilical Cord | 2005 |
Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting.
Topics: Alkaline Phosphatase; Blotting, Western; Chromatography, Affinity; Electrophoresis, Gel, Two-Dimensional; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sorbic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding.
Topics: alpha-Synuclein; Amino Acid Sequence; Humans; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Spectrometry, Fluorescence; Synucleins; Terbium; Titrimetry | 2005 |
Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Endothelium, Vascular; Immunohistochemistry; Interleukin-6; Janus Kinase 1; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Signal Transduction; STAT3 Transcription Factor; Subarachnoid Hemorrhage | 2006 |
Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor.
Topics: 3T3 Cells; Alanine; Animals; Butadienes; Cells, Cultured; Chlorocebus aethiops; COS Cells; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Growth Hormone; Humans; Janus Kinase 2; MAP Kinase Kinase 1; Mass Spectrometry; Mice; Mutation; Nitriles; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Repressor Proteins; STAT5 Transcription Factor; Tetradecanoylphorbol Acetate | 2006 |
Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor.
Topics: Animals; Benzoquinones; Cattle; Cell Movement; Endothelial Cells; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; HSP90 Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Lactams, Macrocyclic; Mice; Mutation; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Transport; rho-Associated Kinases; Swine; Vascular Endothelial Growth Factor A; Vinculin | 2006 |
c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.
Topics: CSK Tyrosine-Protein Kinase; Dimerization; DNA; Endothelial Cells; Gene Expression Regulation; Humans; I-kappa B Proteins; Intercellular Adhesion Molecule-1; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; RNA, Messenger; src-Family Kinases; Thrombin; Transcription Factor RelA | 2007 |
Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes.
Topics: Animals; Cells, Cultured; Dexamethasone; Female; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Male; Muscle Fibers, Skeletal; Phosphoproteins; Phosphoserine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways.
Topics: Animals; Bombesin; Calcium; Carbachol; Cholecystokinin; Dose-Response Relationship, Drug; Enzyme Activation; Growth Substances; Isoenzymes; Male; Mitogen-Activated Protein Kinases; Pancreas, Exocrine; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases | 2007 |
Phosphotyrosine/phosphoserine binary switches: a new paradigm for the regulation of PI3K signalling and growth factor pleiotropy?
Topics: Animals; Cytokines; Growth Substances; Homeostasis; Humans; Intercellular Signaling Peptides and Proteins; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphotyrosine; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Signal Transduction; src Homology Domains | 2007 |
A multiplexed protein kinase assay.
Topics: Cell Extracts; DNA; Enzyme Activation; HeLa Cells; Humans; Isotope Labeling; Molecular Probe Techniques; Oligonucleotides; Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Sensitivity and Specificity; Solutions; Substrate Specificity | 2007 |
Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
Topics: Acetophenones; Benzopyrans; Bronchi; Cadherins; Cell Movement; Cells, Cultured; Endocytosis; Epithelial Cells; GTP-Binding Protein alpha Subunits, Gi-Go; Hepatocyte Growth Factor; Humans; Lysophospholipids; Models, Biological; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Kinase C-delta; Protein Transport; Proto-Oncogene Proteins c-met; RNA, Small Interfering; Signal Transduction | 2007 |
UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbohydrate Dehydrogenases; Electrophoresis; Isoenzymes; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Staphylococcus aureus; Substrate Specificity | 2007 |
Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Cycle; Cell Differentiation; Cell Line; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Genistein; Humans; Leukemia, Promyelocytic, Acute; Membrane Potential, Mitochondrial; Neoplasm Proteins; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Peptide Hydrolases; Phosphoserine; Phosphotyrosine; Promyelocytic Leukemia Protein; Protein Binding; Protein Folding; Protein Structure, Tertiary; Receptors, Retinoic Acid; Repressor Proteins; Transcription Factors; Tretinoin; Tumor Suppressor Proteins | 2007 |
Proteomic approach for caudal trauma-induced acute phase proteins reveals that creatine kinase is a key acute phase protein in amphioxus humoral fluid.
Topics: Acute-Phase Proteins; Animals; Antibodies, Monoclonal; Chordata; Cloning, Molecular; Creatine Kinase; Gene Expression Regulation; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteomics; Spectrometry, Mass, Electrospray Ionization; Time Factors; Wound Healing | 2007 |
Phosphopeptide elution times in reversed-phase liquid chromatography.
Topics: Amino Acid Sequence; Chromatography, Liquid; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Predictive Value of Tests; Proteome; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors; Trifluoroacetic Acid; Trypsin | 2007 |
Phospho.ELM: a database of phosphorylation sites--update 2008.
Topics: Databases, Protein; Internet; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Sequence Alignment; Sequence Analysis, Protein; Software | 2008 |
The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.
Topics: CD3 Complex; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Golgi Apparatus; Humans; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Phospholipase C gamma; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Transport; Proto-Oncogene Proteins c-raf; Receptors, Antigen, T-Cell; src Homology Domains; Substrate Specificity; ZAP-70 Protein-Tyrosine Kinase | 2008 |
Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner.
Topics: Animals; Antigens, Viral, Tumor; Apoptosis; Caspase 3; Culture Media, Serum-Free; Mice; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphotyrosine; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Signal Transduction | 2007 |
Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma.
Topics: Cell Line, Tumor; Cell Nucleus; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-6; Janus Kinases; Microscopy, Fluorescence; Nasopharyngeal Neoplasms; Neoplasm Staging; Neutralization Tests; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Transport; STAT3 Transcription Factor; Up-Regulation; Viral Matrix Proteins | 2008 |
Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Adhesion Molecules; Cell Fusion; Conserved Sequence; Drosophila melanogaster; Drosophila Proteins; Embryo, Nonmammalian; Immunoglobulins; Molecular Sequence Data; Myoblasts; Phenotype; Phosphoserine; Phosphotyrosine; Proline; Protein Structure, Tertiary; Structure-Activity Relationship; Transgenes | 2008 |
TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism.
Topics: Animals; Apoptosis; Benzamides; Caseins; Cells, Cultured; Dioxoles; Epithelial Cells; Gene Expression Regulation; Genes, Dominant; Humans; Janus Kinase 2; Mammary Glands, Animal; Phosphoserine; Phosphothreonine; Phosphotyrosine; Prolactin; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Smad3 Protein; STAT5 Transcription Factor; Transforming Growth Factor beta | 2008 |
Large-scale phosphorylation mapping reveals the extent of tyrosine phosphorylation in Arabidopsis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Conserved Sequence; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Plant Proteins; Protein Structure, Tertiary; Proteome; Sequence Homology, Amino Acid | 2008 |
Phosphorylation and kinetics of mammalian cytochrome c oxidase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Cattle; Electron Transport Complex IV; Kinetics; Mitochondria, Heart; Myocardium; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2008 |
MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling.
Topics: Animals; Cell Differentiation; Cell Line; DNA; Gene Expression Regulation; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Knockout; Mutation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Kinase Inhibitors; Receptors, Antigen, T-Cell, gamma-delta; Receptors, Interleukin-7; Signal Transduction; STAT5 Transcription Factor; Stem Cells; T-Lymphocytes; Transcription, Genetic | 2008 |
The role of phosphorylated residues in peptide-peptide noncovalent complexes formation.
Topics: Arginine; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Static Electricity | 2008 |
JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin.
Topics: Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Epithelium, Corneal; Focal Adhesion Protein-Tyrosine Kinases; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Models, Biological; Mutant Proteins; Paxillin; Phosphorylation; Phosphoserine; Phosphotyrosine | 2008 |
Phosphorylation sites on Tyr28 and the C-terminus of Rad9 are required for inhibition of premature chromosomal condensation across the entire S phase.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; CDC2 Protein Kinase; Cell Cycle Proteins; Chromosomes, Mammalian; Cycloheximide; Embryonic Stem Cells; G1 Phase; Gene Deletion; Hydroxyurea; Mice; Mitosis; Molecular Sequence Data; Phosphoserine; Phosphotyrosine; S Phase; Structure-Activity Relationship; Time Factors | 2008 |
Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1.
Topics: Animals; Cell Adhesion; Colitis; Dextran Sulfate; Humans; Hyaluronic Acid; Intestinal Mucosa; Leukocytes; Mice; Myocytes, Smooth Muscle; Phosphorylation; Phosphoserine; Phosphotyrosine; Poly I-C; STAT1 Transcription Factor; U937 Cells | 2008 |
The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.
Topics: 4-Butyrolactone; beta Catenin; Caco-2 Cells; Cadherins; Cytoplasm; Epithelial Cells; Genistein; Homoserine; Humans; Intercellular Junctions; Membrane Proteins; Occludin; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Pseudomonas aeruginosa; Quorum Sensing; Staurosporine; Zonula Occludens-1 Protein | 2009 |
14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.
Topics: 14-3-3 Proteins; Animals; Cell Line; Cell Survival; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Mast Cells; Mice; Mice, Knockout; Mutation, Missense; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Proto-Oncogene Proteins c-akt; Shc Signaling Adaptor Proteins; Signal Transduction | 2009 |
Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins.
Topics: Animals; Humans; Mass Spectrometry; Mitochondrial Proteins; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine | 2009 |
Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats.
Topics: Animals; Blood Pressure; Cyclic AMP-Dependent Protein Kinases; Drug Tolerance; Enzyme Activation; Ethanol; Injections, Spinal; Male; N-Methylaspartate; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; src-Family Kinases | 2009 |
Developmental switch in NF-kappaB signalling required for neurite growth.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Gene Expression Regulation, Developmental; I-kappa B Kinase; Mice; Neurites; NF-kappa B; Phosphorylation; Phosphoserine; Phosphotyrosine; Signal Transduction; src-Family Kinases | 2009 |
Ultraviolet photodissociation at 266 nm of phosphorylated peptide cations.
Topics: Cations; Mass Spectrometry; Phosphopeptides; Phosphoserine; Phosphotyrosine; Photochemical Processes; Spectroscopy, Fourier Transform Infrared; Ultraviolet Rays | 2009 |
Screening kinase inhibitors with a microarray-based fluorescent and resonance light scattering assay.
Topics: Fluorescent Dyes; Gold; High-Throughput Screening Assays; Light; Metal Nanoparticles; Phosphoserine; Phosphotyrosine; Protein Array Analysis; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Scattering, Radiation; Spectrometry, Fluorescence | 2010 |
Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Death; Cell Survival; Dual-Specificity Phosphatases; Embryonic Development; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mammals; Mass Spectrometry; Mitogen-Activated Protein Kinase Phosphatases; Morphogenesis; Myristic Acid; Phosphoprotein Phosphatases; Phosphoserine; Phosphothreonine; Phosphotyrosine; Signal Transduction; Substrate Specificity; Transfection | 2010 |
mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.
Topics: Animals; Anti-Bacterial Agents; Blotting, Western; Burns; C-Peptide; Disease Models, Animal; Glucose Clamp Technique; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle, Skeletal; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Serine; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2011 |
Light-induced phosphorylation of crystallins in the retinal pigment epithelium.
Topics: Alkaline Phosphatase; Animals; Cattle; Crystallins; Electrophoresis, Gel, Two-Dimensional; Light; Phosphorylation; Phosphoserine; Phosphotyrosine; Proteome; Reproducibility of Results; Retinal Pigment Epithelium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cognition; Enzyme Activation; Female; Humans; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Phosphoserine; Phosphothreonine; Phosphotyrosine; Up-Regulation | 2011 |
Issues associated with the use of phosphospecific antibodies to localise active and inactive pools of GSK-3 in cells.
Topics: Antibodies, Phospho-Specific; Antigens; Cell Nucleus; Cells; Enzyme Activation; Focal Adhesions; Gene Silencing; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Green Fluorescent Proteins; Isoenzymes; Mitosis; Phosphoserine; Phosphotyrosine; Plasmids; RNA, Small Interfering | 2011 |
Inhibition of PI3K binding to activators by serine phosphorylation of PI3K regulatory subunit p85alpha Src homology-2 domains.
Topics: Amino Acid Sequence; Animals; Binding Sites; Class Ia Phosphatidylinositol 3-Kinase; Enzyme Activation; Enzyme Activators; HEK293 Cells; Humans; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Kinase C; Protein Multimerization; Signal Transduction; src Homology Domains; Tetradecanoylphorbol Acetate; Time Factors | 2011 |
Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling.
Topics: Animals; Cell Line, Tumor; Chromatography, Affinity; Computational Biology; Ephrin-B1; Immunoprecipitation; Isotope Labeling; Mice; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Interaction Mapping; Protein Interaction Maps; Proteomics; Rats; Receptors, Eph Family; Signal Transduction; Titanium | 2011 |
Activation of Stat3 in endothelial cells following hypoxia-reoxygenation is mediated by Rac1 and protein Kinase C.
Topics: Acetylcysteine; Cell Hypoxia; Cell Membrane; Cell Nucleus; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Oxygen; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; rac1 GTP-Binding Protein; Reactive Oxygen Species; RNA, Small Interfering; STAT3 Transcription Factor; Transfection | 2012 |
Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Topics: Calorimetry; Cell Cycle Proteins; Cloning, Molecular; Crystallography, X-Ray; Cytoskeletal Proteins; DNA Damage; DNA Repair; Escherichia coli; Genetic Vectors; Histones; Humans; Microscopy, Fluorescence; Models, Molecular; Nerve Tissue Proteins; Phosphoserine; Phosphotyrosine | 2012 |
Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cystathionine beta-Synthase; Dyrk Kinases; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; GRB2 Adaptor Protein; Harmine; Homocysteine; Hyperhomocysteinemia; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt | 2013 |
Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin.
Topics: Animals; beta Catenin; Cadherins; Catenins; Cell Line; Cell Nucleus; Cytosol; Delta Catenin; Embryo, Nonmammalian; Enzyme Activation; Gastrulation; Humans; Models, Biological; Mutant Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-vav; rac1 GTP-Binding Protein; Signal Transduction; Wnt3A Protein; Xenopus | 2012 |
The nuclear localization of glycogen synthase kinase 3β is required its putative PY-nuclear localization sequences.
Topics: Amino Acid Motifs; Amino Acid Sequence; beta Karyopherins; Cell Nucleus; Cell Survival; Enzyme Stability; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Molecular Sequence Data; Mutant Proteins; Nuclear Localization Signals; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Transport; Structure-Activity Relationship; Subcellular Fractions | 2012 |
Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Clone Cells; Contractile Proteins; Female; Filamins; Green Fluorescent Proteins; Humans; Janus Kinase 2; Microfilament Proteins; Models, Biological; Mutant Proteins; p21-Activated Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Prolactin | 2013 |
Hydrogen bond strengths in phosphorylated and sulfated amino acid residues.
Topics: Amino Acids; Arginine; Computational Biology; Databases, Protein; Glutamic Acid; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Peptides; Phosphates; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Processing, Post-Translational; Proteins; Solvents; Static Electricity; Tyrosine | 2013 |
Catalytic DNA with phosphatase activity.
Topics: Catalysis; Chromatography, High Pressure Liquid; DNA, Catalytic; Electrophoresis, Polyacrylamide Gel; Half-Life; Humans; Hydrolysis; In Vitro Techniques; Mass Spectrometry; Oligonucleotides; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Phosphotyrosine; Rosaniline Dyes | 2013 |
Testosterone modulates the expression of molecules linked to insulin action and glucose uptake in endometrial cells.
Topics: Caveolin 1; Cell Line; Deoxyglucose; Endometrium; Female; Glucose; Humans; Insulin; Insulin Receptor Substrate Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Signal Transduction; Testosterone | 2013 |
The Streptococcus thermophilus protein Wzh functions as a phosphotyrosine phosphatase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Enzyme Inhibitors; Escherichia coli; Molecular Sequence Data; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Streptococcus thermophilus; Vanadates | 2013 |
The family-wide structure and function of human dual-specificity protein phosphatases.
Topics: Catalytic Domain; Crystallography, X-Ray; Cysteine; Dual-Specificity Phosphatases; Enzyme Inhibitors; Escherichia coli; Humans; Hydrolysis; Models, Molecular; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Phosphotyrosine; Phylogeny; Protein Structure, Secondary; Recombinant Proteins; Signal Transduction; Structural Homology, Protein; Substrate Specificity | 2014 |
Expanded cellular amino acid pools containing phosphoserine, phosphothreonine, and phosphotyrosine.
Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genetic Engineering; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins | 2014 |
Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody.
Topics: Animals; Antibodies, Phospho-Specific; Antibody Specificity; Cell Nucleus; Green Fluorescent Proteins; Humans; Interleukin-6; Lipopolysaccharides; Liver; Mice; Mitochondria; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Transport; Proto-Oncogene Proteins c-fos; Single-Chain Antibodies; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2014 |
The immune receptor Tim-3 mediates activation of PI3 kinase/mTOR and HIF-1 pathways in human myeloid leukaemia cells.
Topics: Calcium; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Galectins; Hepatitis A Virus Cellular Receptor 2; Humans; Hypoxia-Inducible Factor 1; Leukemia, Myeloid; Ligands; Membrane Proteins; Models, Biological; Phosphatidylinositol 3-Kinase; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Stem Cell Factor; Time Factors; TOR Serine-Threonine Kinases; Type C Phospholipases; Vascular Endothelial Growth Factor A | 2015 |
Serine-727 phosphorylation activates hypothalamic STAT-3 independently from tyrosine-705 phosphorylation.
Topics: Animals; Bradykinin; Cell Line; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Genes, Reporter; Humans; Hypothalamus; Interferon-gamma; Ligands; Melanocyte-Stimulating Hormones; Mice; Neurons; Neuropeptide Y; Phosphorylation; Phosphoserine; Phosphotyrosine; Promoter Regions, Genetic; Receptors, Cytokine; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Thyrotropin-Releasing Hormone; Transcriptional Activation | 2015 |
Modulating platelet reactivity through control of RGS18 availability.
Topics: Animals; Blood Platelets; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Epoprostenol; Fetal Tissue Transplantation; Liver; Liver Transplantation; Mice; Microfilament Proteins; Nerve Tissue Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet Activation; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Radiation Chimera; Receptors, Thrombin; RGS Proteins; Second Messenger Systems; Signal Transduction; Thrombin | 2015 |
Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.
Topics: Amino Acid Sequence; Arginine; DNA Mutational Analysis; Gene Ontology; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Processing, Post-Translational; Proteome; Proto-Oncogene Proteins c-raf; Software; Static Electricity; Sumoylation; Ubiquitination | 2015 |
PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis.
Topics: Animals; beta Catenin; Brain Neoplasms; Carcinogenesis; cdc25 Phosphatases; Cell Line, Tumor; Cell Nucleus; Epidermal Growth Factor; Glioblastoma; Glycolysis; Humans; Mice; Phosphorylation; Phosphoserine; Phosphotyrosine; Prognosis; Protein Binding; Proto-Oncogene Proteins c-myc; Pyruvate Kinase; src-Family Kinases; Transcriptional Activation | 2016 |
Bilateral activation of STAT3 by phosphorylation at the tyrosine-705 (Y705) and serine-727 (S727) positions and its nuclear translocation in primary sensory neurons following unilateral sciatic nerve injury.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Ganglia, Spinal; Male; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Wistar; Sciatic Neuropathy; Sensory Receptor Cells; STAT3 Transcription Factor | 2018 |
Free Radical-Initiated Peptide Sequencing Mass Spectrometry for Phosphopeptide Post-translational Modification Analysis.
Topics: Cyclic N-Oxides; Free Radicals; Mass Spectrometry; Peptide Fragments; Phosphopeptides; Phosphoserine; Phosphotyrosine; Protein Processing, Post-Translational; Protons | 2019 |
Urocortin Induces Phosphorylation of Distinct Residues of Signal Transducer and Activator of Transcription 3 (STAT3) via Different Signaling Pathways.
Topics: Animals; Cell Line; DNA; Interleukin-6; Janus Kinase 2; MAP Kinase Signaling System; Mice; Models, Biological; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Rats; Signal Transduction; STAT3 Transcription Factor; Time Factors; Urocortins | 2019 |
Ste20-like Kinase-mediated Control of Actin Polymerization Is a New Mechanism for Thin Filament-associated Regulation of Airway Smooth Muscle Contraction.
Topics: Acetylcholine; Actin Cytoskeleton; Actins; Adult; Biocatalysis; Cell Cycle Proteins; Female; Histamine; Humans; Lung; Male; Middle Aged; Models, Biological; Multiprotein Complexes; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Paxillin; Phosphorylation; Phosphoserine; Phosphotyrosine; Polo-Like Kinase 1; Polymerization; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Serotonin; Wiskott-Aldrich Syndrome Protein, Neuronal | 2020 |
Substrate Activation of the Low-Molecular Weight Protein Tyrosine Phosphatase from
Topics: Allosteric Site; Bacterial Proteins; Catalytic Domain; Kinetics; Molecular Weight; Mycobacterium tuberculosis; Nitrophenols; Organophosphorus Compounds; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Substrate Specificity | 2020 |
Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antibodies; Cell Line; Cytokines; Humans; Interleukin Receptor Common gamma Subunit; Interleukin-2; MAP Kinase Signaling System; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Processing, Post-Translational; Receptors, Antigen, T-Cell; Signal Transduction; TOR Serine-Threonine Kinases | 2021 |
Dual specificity phosphatase 7 drives the formation of cardiac mesoderm in mouse embryonic stem cells.
Topics: Animals; Dual Specificity Phosphatase 1; Dual-Specificity Phosphatases; Mesoderm; Mice; Mitogen-Activated Protein Kinases; Mouse Embryonic Stem Cells; Phosphoserine; Phosphothreonine; Phosphotyrosine | 2022 |