Page last updated: 2024-08-23

phosphotyrosine and phenylalanine

phosphotyrosine has been researched along with phenylalanine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.27)18.7374
1990's13 (29.55)18.2507
2000's26 (59.09)29.6817
2010's2 (4.55)24.3611
2020's2 (4.55)2.80

Authors

AuthorsStudies
Bishop, JM; Snyder, MA1
Burke, TR; Case, R; Nomizu, M; Otaka, A; Roller, PP; Shoelson, SE; Smyth, MS; Wolf, G1
Chien, P; Huang, MM; Indik, ZK; Mitchell, MA; Pan, XQ; Schreiber, AD1
Burke, TR; Kole, HK; Roller, PP1
Baumann, G; Keller, TH; Manning, U; Mikol, V; Zurini, MG1
Gill, GN; Kurten, RC; Nesterov, A1
Allevato, G; Billestrup, N; Carter-Su, C; VanderKuur, JA; Wang, X; Zhang, L1
Auricchio, F; Castoria, G; Chambon, P; Di Domenico, M; Green, S; Migliaccio, A1
Larsson, E; Lüning, B1
Turck, CW1
Jackson, DE; Kupcho, KR; Newman, PJ1
Betageri, R; Jakes, S; Lukas, S; Proudfoot, JR; Schembri-King, J; Tong, L; Warren, TC1
Burke, TR; Cao, T; Kelley, J; King, CR; Milne, GW; Voigt, JH; Yao, ZJ1
Glover, NR; Tracey, AS1
Sui, X; Xu, F; Xu, M; Zhao, R; Zhao, ZJ1
Burke, TR; Gao, Y; Guo, R; Kelley, J; Luo, J; Voigt, JH; Yang, D; Yao, ZJ; Zou, H1
Budde, RJ; Ke, S; McMurray, JS; Obeyesekere, NU; Ramdas, L; Sun, G; Wang, W1
Billestrup, N; Carter-Su, C; Herrington, J; Stofega, MR1
Blaikie, P; Dans, M; Gagnoux-Palacios, L; Giancotti, FG; Klein, S; Mariotti, A1
Caravatti, G; Denholm, AA; Egerton, J; Faessler, A; Furet, P; García-Echeverría, C; Gay, B; Irving, E; Jones, K; Lambert, A; Press, NJ; Walker, CV; Woods, J1
Rubin, CS; Wu, SL; Zhang, L1
Brunati, AM; Cesaro, L; Donella-Deana, A; Pinna, LA; Ruzzene, M; Sarno, S1
Akhand, AA; Hamaguchi, M; Iwashita, T; Kato, M; Kawamoto, Y; Nakashima, I; Senga, T; Sobue, G; Takahashi, M; Takeda, K; Yamamoto, M1
Badger, KM; Barber, DL; Beattie, BK; Carroll, MP; Dierov, JK; Haq, R; Ho, JM; Nguyen, MH; Tartaro, P; Zanke, BW1
Burke, TR; Lee, K; Yang, D; Zhang, M1
Blaskovich, MA; Kahn, M; Kim, HO; Qabar, M; Urban, J; Yan, Z1
Li, P; Liu, H; Peach, ML; Roller, PP; Yang, D; Zhang, M1
Andersen, HS; Guo, XL; Iversen, LF; Kastrup, JS; Mortensen, SB; Møller, KB; Møller, NP; Pedersen, AK; Peters, GH; Zhang, ZY1
Burke, TR; Cherry, S; Lee, K; Phan, J; Tropea, JE; Waugh, DS1
Qu, LN; Yang, B; Yang, TB; Yuan, YH; Zhao, H; Zhong, P1
Cabanilla, NJ; Diversé-Pierluissi, M; Hains, MD; Lau, KK; Richman, RW; Siderovski, DP; Strock, J1
Ayrapetov, MK; Lee, S; Lin, X; Parang, K; Sun, G1
Bindu, LK; Burke, TR; Fisher, RJ; Kang, SU; Karki, RG; Nicklaus, MC; Oishi, S; Wang, X; Worthy, KM1
Fang, CX; Ontko, AC; Palanichamy, K; Rao, MN; Ren, J; Sreejayan, N; Yang, X1
Beselman, A; Boresch, S; Leitgeb, M; MacKerell, AD1
Bindu, LK; Burke, TR; Fisher, RJ; Kang, SU; Worthy, KM; Yang, D; Zhang, M1
Burke, TR1
Bonvini, E; DeBell, K; Graham, L; Reischl, I; Rellahan, B; Serrano, C1
Chinwong, J; Desamero, RZ; Dol, C; Kang, J; Profit, AA; Sivarajah, T; Walters, K1
Kawasaki, K; Miyazawa, K; Miyazono, K; Sase, H; Watabe, T1
Ha, T; Honda, M; Okuno, Y; Spies, M; Yoo, J1
Ghassemian, M; Lawson, C; Schlaepfer, DD; Tomar, A1
Brzozowski, M; Chen, H; Mao, R; Nguyen, NH; Sleebs, BE1
Accorsi, M; Cruz, R; Emmerling, F; Finn, LM; Heberle, J; Keller, BG; Rademann, J; Rautenberg, M; Tiemann, M; Wehrhan, L1

Reviews

1 review(s) available for phosphotyrosine and phenylalanine

ArticleYear
Design and synthesis of phosphonodifluoromethyl phenylalanine (F2Pmp): a useful phosphotyrosyl mimetic.
    Current topics in medicinal chemistry, 2006, Volume: 6, Issue:14

    Topics: Animals; Binding Sites; Drug Design; Humans; Models, Chemical; Molecular Mimicry; Phenylalanine; Phosphotyrosine; Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains

2006

Other Studies

43 other study(ies) available for phosphotyrosine and phenylalanine

ArticleYear
A mutation at the major phosphotyrosine in pp60v-src alters oncogenic potential.
    Virology, 1984, Jul-30, Volume: 136, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Protein pp60(v-src); Phenylalanine; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins

1984
Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.
    Biochemistry, 1994, May-31, Volume: 33, Issue:21

    Topics: Amino Acid Sequence; Enzyme Inhibitors; Hydrolysis; Molecular Sequence Data; Oncogene Protein pp60(v-src); Phenylalanine; Phosphoric Monoester Hydrolases; Phosphotyrosine; Tyrosine

1994
Substitutions and deletions in the cytoplasmic domain of the phagocytic receptor Fc gamma RIIA: effect on receptor tyrosine phosphorylation and phagocytosis.
    Blood, 1994, Sep-15, Volume: 84, Issue:6

    Topics: Amino Acid Sequence; Animals; Antigens, CD; Cell Line; Cytoplasm; Humans; Molecular Sequence Data; Mutagenesis; Phagocytosis; Phenylalanine; Phosphorylation; Phosphotyrosine; Receptors, IgG; Structure-Activity Relationship; Transfection; Tyrosine

1994
Potent inhibition of insulin receptor dephosphorylation by a hexamer peptide containing the phosphotyrosyl mimetic F2Pmp.
    Biochemical and biophysical research communications, 1994, Oct-14, Volume: 204, Issue:1

    Topics: Amino Acid Sequence; Animals; Cell Membrane; CHO Cells; Cricetinae; Humans; Indicators and Reagents; Kinetics; Molecular Sequence Data; Oligopeptides; Phenylalanine; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptor, Insulin; Recombinant Proteins; Transfection; Tyrosine

1994
The crystal structures of the SH2 domain of p56lck complexed with two phosphonopeptides suggest a gated peptide binding site.
    Journal of molecular biology, 1995, Feb-17, Volume: 246, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein-Tyrosine Kinases; Tyrosine

1995
Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism.
    The Journal of biological chemistry, 1995, Mar-17, Volume: 270, Issue:11

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Blotting, Western; Cattle; Cell Line; Chromatography, Affinity; Cloning, Molecular; Coated Pits, Cell-Membrane; ErbB Receptors; Humans; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Binding; Recombinant Proteins; Sequence Deletion; Tumor Cells, Cultured; Tyrosine

1995
Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor.
    The Journal of biological chemistry, 1995, Sep-15, Volume: 270, Issue:37

    Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Enzyme Activation; Growth Hormone; Humans; Janus Kinase 2; Mutagenesis, Site-Directed; Phenylalanine; Phosphoproteins; Phosphorylation; Phosphotyrosine; Point Mutation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Somatotropin; Recombinant Proteins; Sequence Deletion; Transfection; Tyrosine

1995
Properties of a purified estradiol-dependent calf uterus tyrosine kinase.
    Biochemistry, 1993, Feb-23, Volume: 32, Issue:7

    Topics: Actins; Amino Acid Sequence; Animals; Calcium; Calmodulin; Cattle; Electrophoresis, Polyacrylamide Gel; Estradiol; Female; Histones; Humans; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Denaturation; Protein-Tyrosine Kinases; Receptors, Estradiol; Substrate Specificity; Tyrosine; Uterus

1993
Synthesis of p-phosphonomethyl-L-phenylalanine using camphor sultam or D-valine as chiral auxiliaries and its incorporation into integrin sequences.
    Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1996, Volume: 50, Issue:1

    Topics: Amino Acid Sequence; Camphor; Integrins; Molecular Sequence Data; Phenylalanine; Phosphotyrosine; Valine

1996
High-performance liquid chromatography on-line derivative spectroscopy for the characterization of peptides with aromatic amino acid residues.
    Methods in molecular biology (Clifton, N.J.), 1997, Volume: 64

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Mathematics; Peptide Fragments; Phenylalanine; Phosphotyrosine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine

1997
Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2.
    The Journal of biological chemistry, 1997, Oct-03, Volume: 272, Issue:40

    Topics: Binding Sites; Cell Line; Cytoplasm; DNA Primers; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Phosphopeptides; Phosphotyrosine; Platelet Endothelial Cell Adhesion Molecule-1; Point Mutation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Transfection

1997
Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding.
    The Journal of biological chemistry, 1998, Aug-07, Volume: 273, Issue:32

    Topics: Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Models, Molecular; Molecular Conformation; Molecular Structure; Phenylalanine; Phosphotyrosine; Protein Binding; Protein Conformation; src Homology Domains

1998
Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands.
    Journal of medicinal chemistry, 1999, Jan-14, Volume: 42, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Asparagine; Female; GRB2 Adaptor Protein; Humans; Ligands; Models, Molecular; Molecular Mimicry; Organophosphonates; Phenylalanine; Phosphotyrosine; Protein Binding; Proteins; Receptor, ErbB-2; Recombinant Proteins; src Homology Domains; Structure-Activity Relationship; Surface Plasmon Resonance; Tumor Cells, Cultured

1999
Nuclear magnetic resonance and restrained molecular dynamics studies of the interaction of an epidermal growth factor-derived peptide with protein tyrosine phosphatase 1B.
    Biochemistry, 1999, Apr-20, Volume: 38, Issue:16

    Topics: Alanine; Aspartic Acid; Binding, Competitive; Crystallography, X-Ray; ErbB Receptors; Glutamic Acid; Leucine; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phenylalanine; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Tyrosine Phosphatases; Temperature; Thermodynamics

1999
Tyrosine phosphorylation of myelin P(0) and its implication in signal transduction.
    Biochemical and biophysical research communications, 2000, Jan-27, Volume: 267, Issue:3

    Topics: Amino Acid Sequence; Animals; Animals, Newborn; Brain; Cell Line; Cloning, Molecular; Consensus Sequence; Humans; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Myelin P0 Protein; Neurilemmoma; Phenylalanine; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Sequence Alignment; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates

2000
Inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. 2. 4-(2-Malonyl)phenylalanine as a potent phosphotyrosyl mimetic.
    Journal of medicinal chemistry, 2000, Mar-09, Volume: 43, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Cell Line; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; GRB2 Adaptor Protein; Humans; Ligands; Malonates; Mitogen-Activated Protein Kinases; Models, Molecular; Molecular Mimicry; Phenylalanine; Phosphotyrosine; Protein Binding; Proteins; Receptor, ErbB-2; src Homology Domains; Structure-Activity Relationship

2000
Cyclic peptides incorporating 4-carboxyphenylalanine and phosphotyrosine are potent inhibitors of pp60(c-)(src).
    Biochemistry, 2000, May-02, Volume: 39, Issue:17

    Topics: Animals; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Peptides, Cyclic; Phenylalanine; Phosphotyrosine; Protein-Tyrosine Kinases; src-Family Kinases; Structure-Activity Relationship

2000
Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B.
    Molecular endocrinology (Baltimore, Md.), 2000, Volume: 14, Issue:9

    Topics: 3T3 Cells; Amino Acid Substitution; Animals; Binding Sites; DNA-Binding Proteins; Human Growth Hormone; Humans; Janus Kinase 2; Kinetics; Mice; Milk Proteins; Mutagenesis, Site-Directed; Phenylalanine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Somatotropin; Recombinant Proteins; Signal Transduction; src Homology Domains; STAT5 Transcription Factor; Trans-Activators; Tyrosine

2000
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.
    The Journal of biological chemistry, 2001, Jan-12, Volume: 276, Issue:2

    Topics: Amino Acid Substitution; Antigens, CD; Antigens, Surface; Binding Sites; Cell Line; Cytoplasm; Desmosomes; Enzyme Inhibitors; Humans; Integrin alpha6; Integrin alpha6beta4; Integrin beta4; Integrins; Phenylalanine; Phosphopeptides; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Signal Transduction; src Homology Domains; Transfection; Tyrosine; Vanadates

2001
Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2.
    Bioorganic & medicinal chemistry letters, 2000, Oct-16, Volume: 10, Issue:20

    Topics: Adaptor Proteins, Signal Transducing; Amino Acids; Drug Design; GRB2 Adaptor Protein; Molecular Structure; Phenylalanine; Phosphinic Acids; Phosphotyrosine; Proteins; src Homology Domains; Structure-Activity Relationship

2000
A novel adapter protein employs a phosphotyrosine binding domain and exceptionally basic N-terminal domains to capture and localize an atypical protein kinase C: characterization of Caenorhabditis elegans C kinase adapter 1, a protein that avidly binds pr
    The Journal of biological chemistry, 2001, Mar-30, Volume: 276, Issue:13

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acids; Animals; Animals, Genetically Modified; Base Sequence; Binding Sites; Blotting, Northern; Blotting, Western; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Membrane; Cells, Cultured; Codon; DNA, Complementary; Dogs; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Gene Library; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Phosphotyrosine; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Swine; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques

2001
Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.
    The Biochemical journal, 2001, Jul-15, Volume: 357, Issue:Pt 2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Casein Kinase II; Emodin; Enzyme Inhibitors; Escherichia coli; Heparin; Kinetics; Models, Molecular; Oligopeptides; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein Serine-Threonine Kinases; Protein Subunits; Recombinant Proteins; Substrate Specificity; Tyrosine

2001
Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.
    Cancer research, 2002, Apr-15, Volume: 62, Issue:8

    Topics: 3T3 Cells; Amino Acid Substitution; Animals; Catalysis; Cell Transformation, Neoplastic; Drosophila Proteins; Humans; Mice; Multiple Endocrine Neoplasia Type 2a; Mutagenesis; Phenylalanine; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; src-Family Kinases; Transfection; Tyrosine

2002
TEL-JAK2 constitutively activates the extracellular signal-regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways.
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Cell Line; Enzyme Activation; GRB2 Adaptor Protein; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Mutation; Oncogene Proteins, Fusion; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Proteins; ras Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine

2002
Design and synthesis of a beta-amino phosphotyrosyl mimetic suitably protected for peptide synthesis.
    Bioorganic & medicinal chemistry letters, 2002, Dec-02, Volume: 12, Issue:23

    Topics: Biomimetic Materials; Computer Simulation; Models, Molecular; Peptides; Phenylalanine; Phosphotyrosine; src Homology Domains; Stereoisomerism

2002
Design and synthesis of phosphotyrosine mimetics.
    Bioorganic & medicinal chemistry letters, 2003, Jun-16, Volume: 13, Issue:12

    Topics: Biomimetic Materials; Combinatorial Chemistry Techniques; Drug Design; Enzyme Inhibitors; Peptide Library; Phenylalanine; Phosphotyrosine; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Structure-Activity Relationship

2003
Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists.
    Organic letters, 2003, Aug-21, Volume: 5, Issue:17

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acids; Animals; Breast Neoplasms; Fluorenes; GRB2 Adaptor Protein; Inhibitory Concentration 50; Mice; Molecular Mimicry; Molecular Sequence Data; Peptides, Cyclic; Phenylalanine; Phosphotyrosine; Proteins; Receptor, ErbB-2; src Homology Domains; Stereoisomerism; Tumor Cells, Cultured

2003
Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.
    The Biochemical journal, 2004, Mar-01, Volume: 378, Issue:Pt 2

    Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Catalysis; Enzyme Inhibitors; Histidine; Humans; Hydrolysis; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nitrophenols; Organophosphorus Compounds; Peptides; Phenylalanine; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 3; Protein Tyrosine Phosphatases; Sequence Alignment; Vanadates

2004
High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide.
    Biochemistry, 2003, Nov-18, Volume: 42, Issue:45

    Topics: Anions; Bacterial Outer Membrane Proteins; Binding Sites; Catalytic Domain; Crystallization; Crystallography, X-Ray; Cytoplasm; ErbB Receptors; Humans; Ligands; Macromolecular Substances; Molecular Mimicry; Oligopeptides; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Substrate Specificity; Yersinia pestis

2003
A novel competitive ELISA for both free and protein-bound nitrotyrosine.
    Hybridoma and hybridomics, 2003, Volume: 22, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutaral; Humans; Mice; Peroxynitrous Acid; Phenylalanine; Phosphotyrosine; Protein Binding; Reactive Nitrogen Species; Tyrosine

2003
RGS12 interacts with the SNARE-binding region of the Cav2.2 calcium channel.
    The Journal of biological chemistry, 2005, Jan-14, Volume: 280, Issue:2

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Calcium Channels; Cells, Cultured; Chickens; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channel Gating; Molecular Sequence Data; Neurons; Peptides; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Binding; RGS Proteins; Sequence Alignment; SNARE Proteins; Vesicular Transport Proteins

2005
Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk.
    Biochemistry, 2005, Feb-08, Volume: 44, Issue:5

    Topics: Alanine; Animals; Catalytic Domain; Chickens; Crystallography, X-Ray; CSK Tyrosine-Protein Kinase; Enzyme Activation; Phenylalanine; Phosphopeptides; Phosphotyrosine; Point Mutation; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Sequence Alignment; Sequence Deletion; src Homology Domains; src-Family Kinases; Substrate Specificity; Tryptophan

2005
Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.
    Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Binding Sites; Cyclization; GRB2 Adaptor Protein; Models, Molecular; Molecular Conformation; Molecular Mimicry; Organophosphonates; Phenylalanine; Phosphopeptides; Phosphotyrosine; Protein Binding; src Homology Domains; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

2005
A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.
    FEBS letters, 2005, Feb-28, Volume: 579, Issue:6

    Topics: Adipocytes; Animals; Cell Line; Chromatin; DNA; Glucose; Glucose Tolerance Test; Hydroxyl Radical; Insulin; Male; Mice; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin

2005
Unexpected relative aqueous solubilities of a phosphotyrosine analogue and two phosphonate derivatives.
    Journal of the American Chemical Society, 2005, Apr-06, Volume: 127, Issue:13

    Topics: Computer Simulation; Models, Molecular; Organophosphonates; Peptides; Phenylalanine; Phosphotyrosine; Solubility; src Homology Domains; Thermodynamics; Water

2005
Design and synthesis of 4-(alpha-hydroxymalonyl)phenylalanine as a new phosphotyrosyl mimetic and its use in growth factor receptor bound 2 src-homology 2 (Grb2 SH2) domain-binding peptides.
    Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16

    Topics: Adaptor Proteins, Signal Transducing; Cell Line, Tumor; Drug Design; Esters; GRB2 Adaptor Protein; Humans; Malonates; Oligopeptides; Phenylalanine; Phosphotyrosine; Prodrugs; Receptor, ErbB-2; src Homology Domains; Structure-Activity Relationship; Surface Plasmon Resonance

2005
Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain.
    Molecular and cellular biology, 2007, Volume: 27, Issue:3

    Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Calcium Signaling; Catalysis; Cattle; Chickens; Humans; Kinetics; Membrane Microdomains; Models, Biological; Molecular Sequence Data; Mutation; Phenylalanine; Phospholipase C gamma; Phosphoproteins; Phosphotyrosine; Protein Binding; Receptors, Antigen, B-Cell; src Homology Domains

2007
Spectroscopic characterization of the SH2- and active site-directed peptide sequences of a bivalent Src kinase inhibitor.
    Applied spectroscopy, 2009, Volume: 63, Issue:7

    Topics: Catalytic Domain; Computer Simulation; Models, Chemical; Peptides; Phenylalanine; Phosphotyrosine; Protein Kinase Inhibitors; Solvents; Spectroscopy, Fourier Transform Infrared; src Homology Domains; src-Family Kinases

2009
VEGFR2-PLCgamma1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells.
    Journal of cell science, 2009, Sep-15, Volume: 122, Issue:Pt 18

    Topics: Animals; Blood Vessels; Body Patterning; Cell Differentiation; Cell Survival; Endothelial Cells; Enzyme Activation; Humans; Intracellular Space; Mice; Models, Biological; Mutant Proteins; Phenylalanine; Phospholipase C gamma; Phosphotyrosine; Protein Structure, Tertiary; Recombinant Fusion Proteins; Signal Transduction; Stem Cells; Vascular Endothelial Growth Factor Receptor-2

2009
Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.
    The EMBO journal, 2011, Jul-29, Volume: 30, Issue:16

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Binding, Competitive; DNA; DNA Breaks, Double-Stranded; DNA, Single-Stranded; Genes, Suppressor; Humans; Models, Molecular; Molecular Sequence Data; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-abl; Rad52 DNA Repair and Recombination Protein; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid

2011
Cortactin as a target for FAK in the regulation of focal adhesion dynamics.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Adhesion; Cell Movement; Cortactin; Embryo, Mammalian; Enzyme Activation; Fibroblasts; Fibronectins; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Knockdown Techniques; Mice; Models, Biological; Molecular Sequence Data; Mutation; Phenylalanine; Phosphorylation; Phosphotyrosine; Proline-Rich Protein Domains; Protein Binding; Protein Transport; Rats; Structure-Activity Relationship

2012
Late Stage Phosphotyrosine Mimetic Functionalization of Peptides Employing Metallaphotoredox Catalysis.
    Organic letters, 2021, 06-04, Volume: 23, Issue:11

    Topics: Catalysis; Molecular Structure; Peptides; Phenylalanine; Phosphotyrosine; Signal Transduction

2021
Pentafluorophosphato-Phenylalanines: Amphiphilic Phosphotyrosine Mimetics Displaying Fluorine-Specific Protein Interactions.
    Angewandte Chemie (International ed. in English), 2022, 06-20, Volume: 61, Issue:25

    Topics: Binding Sites; Biomimetics; Enzyme Inhibitors; Fluorides; Fluorine; Models, Molecular; Phenylalanine; Phosphotyrosine

2022