phosphotyrosine has been researched along with losartan potassium in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (73.17) | 18.2507 |
| 2000's | 11 (26.83) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, JW; Altschuler, D; Komatsu, N; Lapetina, EG; Marzocchini, R; Torti, M; Yamamoto, K | 1 |
| D'Andrea, A; Evans, GA; Farrar, WL; Linnekin, D | 1 |
| Damen, J; Hughes, P; Humphries, K; Krystal, G; Mui, AL | 1 |
| Arima, N; Hattori, T; Imada, K; Itoh, K; Kodaka, T; Okuma, M; Tsudo, M; Uchiyama, T | 1 |
| Evans, G; Farrar, WL; Linnekin, D; Michiel, D | 1 |
| Amanuma, H; Chiba, T; Kuramochi, S; Todokoro, K; Tojo, A | 1 |
| David, M; Feldman, GM; Fibach, E; Finbloom, DS; Hackett, RH; Igarashi, K; Petricoin, EF; Silva, CM; Thorner, MO; Weber, MJ | 1 |
| Dusanter, I; Gisselbrecht, S; Gobert, S; Lacombe, C; Mayeux, P; Muller, O | 1 |
| Farrell, FX; Lapetina, EG | 1 |
| Ikawa, Y; Noda, M; Yamamura, Y | 1 |
| Nakaya, K; Nishida, E; Sugiyama, M; Todokoro, K | 1 |
| Aoki, N; Ihle, JN; Miura, O; Miura, Y; Nakamura, N; Quelle, FW; Witthuhn, BA | 1 |
| Ihle, JN; Miura, O; Yi, T; Zhang, J | 1 |
| Bagby, GC; Broxmeyer, HE; Feng, GS; Hoatlin, M; Kabat, D; Lu, L; Shen, R; Tauchi, T | 1 |
| Hanazono, Y; Hirai, H; Nitta, H; Sasaki, K; Yazaki, Y | 1 |
| Hanazono, Y; Hirai, H; Iwamatsu, A; Mitani, K; Odai, H; Sasaki, K; Tanaka, T; Yazaki, Y | 1 |
| He, TC; Jiang, N; Wojchowski, DM; Zhuang, H | 1 |
| Courtois, G; Dusanter-Fourt, I; Gisselbrecht, S; Gobert, S; Lacombe, C; Mayeux, P; Muller, O; Pallu, S; Porteu, F; Sabbah, M | 1 |
| Bittorf, T; Busfield, SJ; Callus, B; Cull, VS; Klinken, SP; Tilbrook, PA | 1 |
| Chiba, S; Hanazono, Y; Hirai, H; Mano, H; Sasaki, K; Yazaki, Y | 1 |
| Bittorf, T; Busfield, SJ; Chappell, D; Klinken, SP; Tilbrook, PA | 1 |
| Ihle, JN; Kitazawa, J; Stravopodis, D; Teglund, S; Wang, D | 1 |
| Hirai, H; Iwamatsu, A; Mitani, K; Nakamoto, T; Odai, H; Sasaki, K; Ueno, H; Yamagata, T; Yazaki, Y | 1 |
| Band, H; Barber, DL; D'Andrea, AD; Druker, BJ; Fukazawa, T; Mason, JM; Reedquist, KA | 1 |
| Batac, J; Crouse, J; Pacifici, R; Sharlow, ER; Todokoro, K; Wojchowski, DM | 1 |
| Klingmüller, U | 1 |
| Conrad, KP; Fairchild Benyo, D | 1 |
| Chrétien, S; Fichelson, S; Gisselbrecht, S; Lacombe, C; Lecoq-Lafon, C; Mayeux, P; Verdier, F | 1 |
| Hawley, RG; Ilaria, RL; Van Etten, RA | 1 |
| Ahmad, S; Alsayed, Y; Chen, F; Hibi, M; Hirano, T; Krystal, G; Nishada, K; Platanias, LC; Sawyer, ST; Sharma, A; Uddin, S; Wickrema, A; Yi, T | 1 |
| Barber, DL; Beattie, BK; Dumont, DJ; Liu, Q; Mason, JM | 1 |
| Barber, DL; Beattie, BK; D'Andrea, AD; Frank, DA; Mason, JM; Neel, BG; Nguyen, MH; Yoakim, M | 1 |
| Campana, WM; Myers, RR | 1 |
| Bittorf, T; Brock, J; Büchse, T; Jaster, R; Sasse, T | 1 |
| Ishida, T; Kamano, H; Kitanaka, A; Kubota, Y; Ohnishi, H; Okutani, Y; Takahara, J; Tanaka, T | 1 |
| Fujita, Y; Matsuo, T; Mori, S; Musha, T; Nakamatsu, K; Nakamura, Y; Shiokawa, S; Tanaka, H; Yasuda, Y | 1 |
| Hegde, S; Karur, VG; Li, K; Menon, MP; Wojchowski, DM | 1 |
| Hegde, S; Li, K; Miller, C; Wojchowski, D | 1 |
| Grossmann, KS; Löwenberg, B; Parren-van Amelsvoort, M; Schaeper, U; Toney-Earley, K; van den Akker, E; van Dijk, T; von Lindern, M; Waltz, SE | 1 |
| Arai, A; Jin, ZH; Kurosu, T; Miura, O; Yamaguchi, M | 1 |
| Funakoshi-Tago, M; Ihle, JN; Kasahara, T; Parganas, E; Tago, K | 1 |
2 review(s) available for phosphotyrosine and losartan potassium
| Article | Year |
|---|---|
Rap1b and platelet function.
Topics: Amino Acid Sequence; Blood Platelets; Erythropoietin; GTP-Binding Proteins; GTPase-Activating Proteins; Humans; Iloprost; Isoenzymes; Molecular Sequence Data; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Platelet Activation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins p21(ras); rap GTP-Binding Proteins; ras GTPase-Activating Proteins; Sequence Homology, Amino Acid; Signal Transduction; Thrombin; Type C Phospholipases; Tyrosine | 1993 |
The role of tyrosine phosphorylation in proliferation and maturation of erythroid progenitor cells--signals emanating from the erythropoietin receptor.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Humans; Phosphorylation; Phosphotyrosine; Receptors, Erythropoietin; Signal Transduction | 1997 |
39 other study(ies) available for phosphotyrosine and losartan potassium
| Article | Year |
|---|---|
Erythropoietin rapidly induces tyrosine phosphorylation in the human erythropoietin-dependent cell line, UT-7.
Topics: Erythropoietin; Guanosine Triphosphate; Hematopoiesis; Humans; In Vitro Techniques; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1992 |
Association of the erythropoietin receptor with protein tyrosine kinase activity.
Topics: Adenosine Triphosphate; Animals; Electrophoresis, Gel, Two-Dimensional; Erythropoietin; Friend murine leukemia virus; Gene Products, env; Macromolecular Substances; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Erythropoietin; Signal Transduction; Tyrosine | 1992 |
Erythropoietin-induced tyrosine phosphorylations in a high erythropoietin receptor-expressing lymphoid cell line.
Topics: Animals; B-Lymphocytes; Cell Line; Cross-Linking Reagents; DNA; Erythropoietin; Gene Expression; Immunoblotting; Interleukin-3; Kinetics; Mice; Phenylhydrazines; Phosphorylation; Phosphotyrosine; Receptors, Erythropoietin; RNA, Messenger; Signal Transduction; Transfection; Tyrosine | 1992 |
Interleukin-2 (IL-2) induces erythroid differentiation and tyrosine phosphorylation in ELM-I-1 cells transfected with a human IL-2 receptor beta chain cDNA.
Topics: Animals; Cell Differentiation; Erythropoietin; Humans; Interleukin-2; Kinetics; Leukemia, Erythroblastic, Acute; Macromolecular Substances; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Interleukin-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tyrosine | 1992 |
Characterization of a 97-kDa phosphotyrosylprotein regulated by multiple cytokines.
Topics: Adenosine Triphosphate; Cell Line; Cytokines; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Erythropoietin; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-2; Interleukin-3; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Tyrosine | 1992 |
Growth signal erythropoietin activates the same tyrosine kinases as interleukin 3, but activates only one tyrosine kinase as differentiation signal.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Division; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Erythropoietin; Interleukin-3; Kinetics; Leukemia, Experimental; Mice; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1991 |
Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation.
Topics: Base Sequence; Cell Line; Deoxyribonucleoproteins; DNA-Binding Proteins; Enhancer Elements, Genetic; Erythropoietin; Gene Expression Regulation; Growth Hormone; Humans; In Vitro Techniques; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Tyrosine | 1994 |
Intracellular pathways activated by erythropoietin.
Topics: Cell Line; Erythropoietin; Growth Substances; Hematopoietic Cell Growth Factors; Humans; Leukemia, Erythroblastic, Acute; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Receptors, Erythropoietin; Signal Transduction; Stem Cell Factor; Transfection; Tumor Cells, Cultured; Tyrosine | 1994 |
Activated Ki-Ras complements erythropoietin signaling in CTLL-2 cells, inducing tyrosine phosphorylation of a 160-kDa protein.
Topics: Cell Division; Cell Line; Erythropoietin; Genes, ras; Genes, src; Humans; Janus Kinase 2; Molecular Weight; Oncogenes; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptors, Erythropoietin; Signal Transduction; T-Lymphocytes, Cytotoxic; Transfection; Tyrosine | 1994 |
Activation of mitogen-activated protein kinase cascade through erythropoietin receptor.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Erythropoietin; Humans; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Phosphoproteins; Phosphorylation; Phosphotyrosine; Promoter Regions, Genetic; Protein Kinases; Protein-Tyrosine Kinases; Receptors, Erythropoietin; Receptors, Interleukin-2; Signal Transduction; Transfection; Transferrin; Tyrosine | 1994 |
Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor.
Topics: Amino Acid Sequence; Cell Cycle Proteins; Cell Line; Erythropoietin; Gene Expression Regulation; Humans; Janus Kinase 2; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Point Mutation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Proto-Oncogene Proteins c-vav; Receptors, Erythropoietin; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tyrosine | 1994 |
Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: identification of potential binding sites.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Disulfides; Erythropoietin; Immunosorbent Techniques; Interleukin-3; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Mice; Molecular Sequence Data; Peptide Fragments; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Erythropoietin; Recombinant Fusion Proteins; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Tyrosine | 1995 |
Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; ErbB Receptors; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; GRB2 Adaptor Protein; Hematopoietic Stem Cells; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Receptors, Erythropoietin; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; Transfection; Tyrosine | 1995 |
Erythropoietin induces tyrosine phosphorylation of the beta chain of the GM-CSF receptor.
Topics: Amino Acid Sequence; Cell Line; Electrophoresis, Polyacrylamide Gel; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Macromolecular Substances; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Erythropoietin; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Recombinant Proteins; Tyrosine | 1995 |
The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Binding Sites; Consensus Sequence; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; GRB2 Adaptor Protein; Hematopoietic Stem Cells; Humans; Molecular Sequence Data; Phosphotyrosine; Protein Binding; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Sequence Alignment; Sequence Homology, Amino Acid; Tyrosine; Ubiquitin-Protein Ligases | 1995 |
Erythropoietin-induced recruitment of Shc via a receptor phosphotyrosine-independent, Jak2-associated pathway.
Topics: Animals; Base Sequence; Blotting, Western; Cell Division; Cell Line; DNA Primers; Enzyme Activation; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Janus Kinase 2; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Tyrosine | 1995 |
Tyrosine phosphorylation of the erythropoietin receptor: role for differentiation and mitogenic signal transduction.
Topics: Cell Differentiation; Cell Line; Enzyme Activation; Erythropoiesis; Erythropoietin; Gene Expression Regulation; Globins; Hematopoietic Stem Cells; Interleukin-3; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Erythropoietin; Recombinant Fusion Proteins; Sequence Deletion; Signal Transduction; Transfection; Tyrosine | 1995 |
Amiloride suppresses erythropoietin-induced proliferation and MAP kinase, but potentiates differentiation of J2E cells.
Topics: Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Erythrocytes; Erythropoietin; Genistein; Hemoglobins; Humans; Immunoblotting; Isoflavones; Kinetics; Leucine; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Thymidine; Tyrosine | 1995 |
Erythropoietin induces tyrosine phosphorylation and kinase activity of the c-fps/fes proto-oncogene product in human erythropoietin-responsive cells.
Topics: Amino Acid Sequence; Blotting, Western; Cell Differentiation; Cell Division; Erythropoietin; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosorbent Techniques; Interleukin-3; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Tumor Cells, Cultured; Tyrosine | 1993 |
Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin.
Topics: 3T3 Cells; Animals; Apoptosis; Butyrates; Butyric Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Enzyme Activation; Erythropoietin; GTPase-Activating Proteins; Isoenzymes; Mice; Mutagenesis; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Polymerase Chain Reaction; Proteins; Receptors, Erythropoietin; Signal Transduction; Type C Phospholipases | 1996 |
Naturally occurring dominant negative variants of Stat5.
Topics: Amino Acid Sequence; Animals; Antibodies; Cell Division; Cell Line; DNA-Binding Proteins; Erythropoietin; Genes, Dominant; Genetic Variation; Introns; Kinetics; Mice; Milk Proteins; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Sequence Deletion; Sheep; STAT5 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 1996 |
Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Base Sequence; Cell Transformation, Neoplastic; Cloning, Molecular; DNA, Complementary; Erythropoietin; Fusion Proteins, bcr-abl; Genes; Granulocyte-Macrophage Colony-Stimulating Factor; GRB2 Adaptor Protein; Humans; Leukemia, Megakaryoblastic, Acute; Molecular Sequence Data; Neoplasm Proteins; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Recombinant Fusion Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tumor Cells, Cultured; Ubiquitin-Protein Ligases | 1997 |
Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins.
Topics: Adaptor Proteins, Signal Transducing; Cell Line; Erythropoietin; Humans; Interleukin-3; Kinetics; Models, Biological; Nuclear Proteins; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptors, Erythropoietin; Signal Transduction; src Homology Domains; Ubiquitin-Protein Ligases | 1997 |
Hematopoietic cell phosphatase negatively regulates erythropoietin-induced hemoglobinization in erythroleukemic SKT6 cells.
Topics: Animals; Blotting, Western; Cell Differentiation; DNA-Binding Proteins; ErbB Receptors; Erythroid-Specific DNA-Binding Factors; Erythropoiesis; Erythropoietin; GATA1 Transcription Factor; Globins; Hemoglobins; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Leukemia, Erythroblastic, Acute; Mice; Milk Proteins; Oligonucleotides, Antisense; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Recombinant Fusion Proteins; STAT5 Transcription Factor; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured | 1997 |
Expression of the erythropoietin receptor by trophoblast cellsin the human placenta.
Topics: Blotting, Western; Cells, Cultured; Erythropoietin; Female; Gene Expression; Gestational Age; Humans; Immunohistochemistry; Phosphorylation; Phosphotyrosine; Placenta; Pre-Eclampsia; Pregnancy; Receptors, Erythropoietin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trophoblasts | 1999 |
Erythropoietin induces the tyrosine phosphorylation of GAB1 and its association with SHC, SHP2, SHIP, and phosphatidylinositol 3-kinase.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Erythropoietin; Fetal Blood; Hematopoietic Stem Cells; Humans; Intracellular Signaling Peptides and Proteins; Leukemia; Molecular Weight; Phosphatidylinositol 3-Kinases; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Recombinant Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Transfection; Tumor Cells, Cultured | 1999 |
Dominant negative mutants implicate STAT5 in myeloid cell proliferation and neutrophil differentiation.
Topics: Amino Acid Sequence; Animals; Cell Differentiation; Cell Division; Cell Line; Dimerization; DNA; DNA-Binding Proteins; Erythropoietin; Granulocyte Colony-Stimulating Factor; Granulocytes; Janus Kinase 2; Mice; Milk Proteins; Molecular Sequence Data; Mutagenesis; Neutrophils; Phosphotyrosine; Point Mutation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; STAT5 Transcription Factor; Trans-Activators; Transcriptional Activation | 1999 |
Engagement of Gab1 and Gab2 in erythropoietin signaling.
Topics: Adaptor Proteins, Signal Transducing; Cell Line; Erythropoietin; Hematopoietic Stem Cells; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Erythropoietin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 1999 |
The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Cell Line; Enzyme Activation; Erythropoietin; GRB2 Adaptor Protein; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Erythropoietin; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tyrosine | 2000 |
A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation.
Topics: Animals; Antibody Specificity; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Epitopes; Erythropoietin; Mice; Mice, Inbred C57BL; Milk Proteins; Models, Biological; Peptide Fragments; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Denaturation; Protein Processing, Post-Translational; Rabbits; Receptors, Erythropoietin; Sheep; src Homology Domains; STAT5 Transcription Factor; Trans-Activators | 2001 |
Erythropoietin and erythropoietin receptors in the peripheral nervous system: changes after nerve injury.
Topics: Animals; Binding Sites; Constriction; Erythropoietin; Ganglia, Spinal; Immunohistochemistry; Immunosorbent Techniques; Janus Kinase 2; Nerve Crush; Neurons; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Erythropoietin; Schwann Cells; Sciatic Nerve; Trauma, Nervous System; Wallerian Degeneration | 2001 |
Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance.
Topics: Animals; Apoptosis; Cell Line; Enhancer Elements, Genetic; Enzyme Inhibitors; Erythropoietin; Genes, Reporter; Janus Kinase 2; Mice; Mutation; NF-kappa B; Phosphotyrosine; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Signal Transduction; src-Family Kinases; Tyrphostins | 2001 |
Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway.
Topics: Animals; Cell Line; COS Cells; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Erythropoietin; Hematopoietic Stem Cells; Humans; Janus Kinase 2; K562 Cells; Milk Proteins; Mutation; Oligoribonucleotides, Antisense; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Trans-Activators; Tumor Suppressor Proteins | 2001 |
Expression of erythropoietin in human female reproductive organs.
Topics: Blotting, Southern; Blotting, Western; Cervix Uteri; DNA-Binding Proteins; Endometrium; Erythropoietin; Female; Gene Expression; Genitalia, Female; Humans; Janus Kinase 2; Milk Proteins; Ovary; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; STAT5 Transcription Factor; Trans-Activators | 2001 |
Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor cells.
Topics: Anemia; Animals; Bone Marrow Cells; Cell Differentiation; Cell Division; Cell Survival; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Janus Kinase 2; Mice; Mice, Transgenic; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Signal Transduction; Spleen | 2003 |
Roles for an Epo receptor Tyr-343 Stat5 pathway in proliferative co-signaling with kit.
Topics: Animals; Binding Sites; Cell Division; Cell Line; Cell Separation; Cytokines; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Epidermal Growth Factor; Erythropoietin; Flow Cytometry; Hematopoietic Stem Cells; Mice; Milk Proteins; Models, Genetic; Mutation; Phosphotyrosine; Proto-Oncogene Proteins c-kit; Receptors, Erythropoietin; Retroviridae; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Tyrosine | 2003 |
Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Differentiation; Cell Line; Chlorocebus aethiops; Erythropoietin; Hematopoietic Stem Cells; Hemoglobins; Humans; Janus Kinase 2; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rabbits; Receptor Protein-Tyrosine Kinases; Receptors, Erythropoietin | 2004 |
Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.
Topics: Animals; Apoptosis; Cell Cycle; Cell Division; Cell Line; Cell Line, Tumor; Checkpoint Kinase 1; Cytokines; Erythropoietin; Etoposide; Flow Cytometry; G2 Phase; Glycogen Synthase Kinase 3; Humans; Interleukin-3; Leukemia; Mice; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt | 2005 |
Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway.
Topics: Animals; Colony-Forming Units Assay; Conserved Sequence; Enzyme Activation; Erythroid Cells; Erythropoietin; Interferon-gamma; Janus Kinase 2; Mice; Mutation; Phosphorylation; Phosphotyrosine; Signal Transduction | 2008 |