phosphotyrosine has been researched along with inositol 1,4,5-trisphosphate in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.56) | 18.7374 |
| 1990's | 32 (82.05) | 18.2507 |
| 2000's | 6 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liao, F; Rhee, SG; Shin, HS | 1 |
| Coggeshall, KM; Fukamachi, H; Inagaki, N; Ishizaka, K; Ishizaka, T; Kawakami, T; Takei, M | 1 |
| Earp, HS; Harden, TK; Hepler, JR; Huckle, WR; Jeffs, RA; Outlaw, HE; Rhee, SG | 1 |
| Carpenter, G; Hernández-Sotomayor, SM; Nishibe, S; Rhee, SG; Tonks, NK; Wahl, MI | 1 |
| Carpenter, G; Nishibe, S; Rhee, SG; Suh, PG; Wahl, MI | 1 |
| Borel, JP; Garnotel, R; Haye, B; Monboisse, JC; Randoux, A | 1 |
| Furuno, T; Ikebuchi, H; Nakanishi, M; Sawada, J; Terao, T; Teshima, R | 1 |
| Ikebuchi, H; Nakanishi, M; Sawada, J; Teshima, R | 1 |
| Homma, MK; Homma, Y; Namba, M; Yuasa, Y | 1 |
| Avallone, A; D'Alto, V; Fattore, M; Florio, T; Meucci, O; Schettini, G; Scorziello, A | 1 |
| Dytoc, MT; Ismaili, A; Philpott, DJ; Sherman, PM | 1 |
| Koide, Y; Ryu, K; Yamashita, Y; Yoshida, TO | 1 |
| Mizuno, K; Nakamura, T; Nozawa, Y; Okano, Y; Osada, S | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| Fletcher, MC; June, CH; Samelson, LE | 1 |
| Kabouridis, PS; McGuire, KL; Stanners, J; Tsoukas, CD | 1 |
| Cohen, DA; Fitzpatrick, EA; Kaplan, AM | 1 |
| Jayaraman, T; Marks, AR; Ondrias, K; Ondriasová, E | 1 |
| Puceat, M; Vassort, G | 1 |
| Datta, K; Deb, TB; Rao, CM | 1 |
| Lanier, LL; Parham, P; Phillips, JH; Valiante, NM | 1 |
| Bedzyk, WD; Cambier, JC; Pao, LI; Persin, C | 1 |
| Akagawa, KS; Maeda, M; Matsuura, K; Shinji, H; Tsuji, M; Yamada, R; Yamamoto, S; Yoshida, T | 1 |
| Higashida, H; Kimura, Y; Taketo, M; Yokoyama, S | 1 |
| Beaufils, P; Cambier, JC; Jensen, WA; Malissen, B; Pleiman, CM; Wegener, AM | 1 |
| Inoue, T; Itoh, H; Kume, S; Mikoshiba, K; Nagao, M; Nakanishi, S; Sekiyama, N; Umemori, H; Yamamoto, T | 1 |
| Chen, PB; Contessa, JN; Dent, P; Kavanagh, BD; Mikkelsen, RB; Rorrer, WK; Schmidt-Ullrich, RK; Todd, DG; Valerie, K | 1 |
| Goutsouliak, V; Rabkin, SW | 1 |
| Abrams, JT; Yassin, RR | 1 |
| Barker, SA; Caldwell, KK; Pfeiffer, JR; Wilson, BS | 1 |
| Bergantino, E; Brunati, AM; Cirri, P; Donella-Deana, A; Pinna, LA; Ramponi, G; Ruzzene, M | 1 |
| Calder, PC; Sanderson, P | 1 |
| Lara, M; Lee, I; Lee, RJ; Martinez, AM; Oliver, JM; Ortega, E; Pfeiffer, JR; Santana, C; Wilson, BS | 1 |
| Aussel, C; Breittmayer, JP; Pelassy, C | 1 |
| Backer, JM; Gaudet, EA; Mitchell, CA; Smith, AJ; Surviladze, Z; Wilson, BS | 1 |
| Batty, IH; Downes, CP; Fleming, IN | 1 |
| Bae, YS; Choi, JH; Hong, WP; Kim, HS; Lee, JR; Park, JB; Ryu, SH; Suh, PG; Yun, S | 1 |
| Cui, J; deSouza, N; Dura, M; Marks, AR; McDonald, TV | 1 |
| Choi, OH; Lee, HS; Park, CS; Ryu, SD; Suk, HY | 1 |
39 other study(ies) available for phosphotyrosine and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.
Topics: Antigens, Differentiation; Arsenicals; Calcium; Cell Line; Cross-Linking Reagents; Humans; Immunoglobulin G; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Phosphates; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Receptors, Fc; Receptors, IgG; Type C Phospholipases; Tyrosine | 1992 |
Tyrosine phosphorylation is required for mast cell activation by Fc epsilon RI cross-linking.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cross-Linking Reagents; Genistein; Histamine Release; Immunoglobulin E; Inositol 1,4,5-Trisphosphate; Isoflavones; Mast Cells; Mice; Mice, Inbred CBA; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fc; Receptors, IgE; Signal Transduction; Type C Phospholipases; Tyrosine | 1992 |
Evidence that the epidermal growth factor receptor and non-tyrosine kinase hormone receptors stimulate phosphoinositide hydrolysis by independent pathways.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cell Line; Epidermal Growth Factor; Epinephrine; Epithelium; ErbB Receptors; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Liver; Mice; Phosphotyrosine; Protein Kinase C; Rats; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Thionucleotides; Tyrosine | 1990 |
Increase of the catalytic activity of phospholipase C-gamma 1 by tyrosine phosphorylation.
Topics: Catalysis; Diglycerides; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Immunosorbent Techniques; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1990 |
Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium.
Topics: Adenosine Triphosphate; Antibodies, Monoclonal; Bradykinin; Calcium; Cell Line; Epidermal Growth Factor; ErbB Receptors; Immunoassay; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Type C Phospholipases; Tyrosine | 1989 |
The binding of type I collagen to lymphocyte function-associated antigen (LFA) 1 integrin triggers the respiratory burst of human polymorphonuclear neutrophils. Role of calcium signaling and tyrosine phosphorylation of LFA 1.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antigens, CD; Calcium; CD18 Antigens; Cell Adhesion; Collagen; Cytosol; Enzyme Inhibitors; Genistein; Humans; Immunoglobulin G; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Integrin alpha1; Isoflavones; Kinetics; Lymphocyte Function-Associated Antigen-1; Molecular Sequence Data; Neutrophils; Oligopeptides; Peptide Fragments; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Superoxides | 1995 |
Effects of herbimycin A and ST638 on Fc epsilon receptor-mediated histamine release and Ca2+ signals in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antibodies, Monoclonal; Benzoquinones; Calcium; Cell Line; Cinnamates; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fura-2; Histamine Release; Inositol 1,4,5-Trisphosphate; Kinetics; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Receptors, IgG; Rifabutin; Sulfides; Tumor Cells, Cultured; Tyrosine | 1994 |
Stimulatory effect of pervanadate on calcium signals and histamine secretion of RBL-2H3 cells.
Topics: Animals; Calcium; Catalase; Histamine Release; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Leukemia, Basophilic, Acute; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Enhanced phosphoinositide metabolism in colorectal carcinoma cells derived from familial adenomatous polyposis patients.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Cell Line; Chromatography, Affinity; Colorectal Neoplasms; Diglycerides; Electrophoresis, Polyacrylamide Gel; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Phosphotyrosine; RNA, Messenger; Second Messenger Systems; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1994 |
Alpha 1 B, but not alpha 1A, adrenoreceptor activates calcium influx through the stimulation of a tyrosine kinase/phosphotyrosine phosphatase pathway, following noradrenaline-induced emptying of IP3 sensitive calcium stores, in PC Cl3 rat thyroid cell lin
Topics: Animals; Calcium; Cells, Cultured; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Norepinephrine; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Adrenergic, alpha; Signal Transduction; Thyroid Gland; Tyrosine; Vanadates | 1995 |
Signal transduction responses following adhesion of verocytotoxin-producing Escherichia coli.
Topics: Bacterial Adhesion; Bacterial Toxins; Calcium; Cell Line; Enterotoxins; Escherichia coli; Humans; Inositol 1,4,5-Trisphosphate; Phosphorylation; Phosphotyrosine; Shiga Toxin 1; Signal Transduction; Tyrosine | 1995 |
Inhibition of tyrosine phosphorylation prevents IFN-gamma-induced HLA-DR molecule expression.
Topics: Benzoquinones; Calcimycin; Calcium; Genistein; HLA-DR Antigens; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Interferon-gamma; Isoflavones; Lactams, Macrocyclic; Nitriles; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Recombinant Proteins; Rifabutin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1993 |
Tyrosine phosphorylation of phospholipase C gamma in c-met/HGF receptor-stimulated hepatocytes: comparison with HepG2 hepatocarcinoma cells.
Topics: Animals; Cells, Cultured; Hepatocyte Growth Factor; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Liver; Liver Neoplasms, Experimental; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-met; Rats; Receptors, Cell Surface; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1993 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
Complex effects of phenylarsine oxide in T cells. Induction of tyrosine phosphorylation and calcium mobilization independent of CD45 expression.
Topics: Arsenicals; Calcium; CD3 Complex; Dimercaprol; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Leukocyte Common Antigens; Lymphocyte Activation; Molecular Weight; Phosphoproteins; Phosphotyrosine; T-Lymphocytes; Tyrosine | 1993 |
Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling.
Topics: Antibodies, Monoclonal; Base Sequence; Blotting, Western; Cell Line; Cell Membrane; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Isoflavones; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Transfection | 1995 |
Defective CD4+ T cell signaling in murine AIDS: uncoupling of the T cell receptor complex from PIP2 hydrolysis.
Topics: Animals; Calcium; CD28 Antigens; CD4-Positive T-Lymphocytes; Female; Inositol 1,4,5-Trisphosphate; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphotyrosine; Receptors, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation.
Topics: Animals; Brain; Calcium; Calcium Channels; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lipid Bilayers; Lymphocyte Activation; Mice; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Receptors, Cytoplasmic and Nuclear; T-Lymphocytes; Tumor Cells, Cultured | 1996 |
Purinergic stimulation of rat cardiomyocytes induces tyrosine phosphorylation and membrane association of phospholipase C gamma: a major mechanism for InsP3 generation.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Genistein; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoenzymes; Isoflavones; Kinetics; Male; Myocardium; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Type C Phospholipases | 1996 |
Hyaluronic acid induced hyaluronic acid binding protein phosphorylation and inositol triphosphate formation in lymphocytes.
Topics: Animals; Antibodies; Cell Aggregation; Cells, Cultured; Concanavalin A; Hyaluronan Receptors; Hyaluronic Acid; Inositol 1,4,5-Trisphosphate; Lymphocytes; Molecular Weight; Phosphorylation; Phosphotyrosine; Rats; Signal Transduction; Spleen | 1996 |
Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-gamma signaling complex in human natural killer (NK) cells.
Topics: Adaptor Proteins, Signal Transducing; Calcium; GRB2 Adaptor Protein; HLA-B Antigens; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Killer Cells, Natural; Kinetics; Phosphotyrosine; Protein Kinase C; Proteins; Receptors, Immunologic; Signal Transduction; Transfection | 1996 |
Molecular targets of CD45 in B cell antigen receptor signal transduction.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Agammaglobulinaemia Tyrosine Kinase; Cell Cycle Proteins; Cells, Cultured; GRB2 Adaptor Protein; Humans; Inositol 1,4,5-Trisphosphate; Leukocyte Common Antigens; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plasmacytoma; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-vav; Receptors, Antigen, B-Cell; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src-Family Kinases; Type C Phospholipases | 1997 |
Lipopolysaccharide-induced biphasic inositol 1,4,5-trisphosphate response and tyrosine phosphorylation of 140-kilodalton protein in mouse peritoneal macrophages.
Topics: Animals; Benzoquinones; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Isoenzymes; Lactams, Macrocyclic; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Molecular Weight; Phospholipase C gamma; Phosphoproteins; Phosphotyrosine; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Quinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Rifabutin; Signal Transduction; Type C Phospholipases | 1997 |
Ca2+ release and Ca2+ influx in Chinese hamster ovary cells expressing the cloned mouse B2 bradykinin receptor: tyrosine kinase inhibitor-sensitive and- insensitive processes.
Topics: Animals; Binding Sites; Bradykinin; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Genistein; Homeostasis; Inositol 1,4,5-Trisphosphate; Isoflavones; Manganese; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Bradykinin B2; Receptors, Bradykinin; Thapsigargin; Transfection | 1997 |
Qualitatively distinct signaling through T cell antigen receptor subunits.
Topics: Amino Acid Sequence; Animals; Calcium; CD3 Complex; CD8 Antigens; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Isoenzymes; Mice; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Signal Transduction; Structure-Activity Relationship; Type C Phospholipases | 1997 |
Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit.
Topics: Animals; Calcium; Carbachol; Cell Line; CHO Cells; Cricetinae; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoflavones; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Cholinergic; Receptors, Metabotropic Glutamate; Signal Transduction | 1997 |
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation.
Topics: Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Division; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Nitriles; Phospholipase C gamma; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Quinazolines; Radiation, Ionizing; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins | 1997 |
Angiotensin II-induced inositol phosphate generation is mediated through tyrosine kinase pathways in cardiomyocytes.
Topics: Angiotensin II; Animals; Cells, Cultured; Chick Embryo; Heart; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Myocardium; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction | 1997 |
Gastrin induces IP3 formation through phospholipase C gamma 1 and pp60c-src kinase.
Topics: Animals; Antibodies; Cells, Cultured; Enzyme Inhibitors; Gastrins; Genistein; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; Isoenzymes; Male; Pertussis Toxin; Phospholipase C beta; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Precipitin Tests; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Sprague-Dawley; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella | 1998 |
Wortmannin-sensitive phosphorylation, translocation, and activation of PLCgamma1, but not PLCgamma2, in antigen-stimulated RBL-2H3 mast cells.
Topics: Androstadienes; Animals; Antigens; Biological Transport; Cell Membrane; Dinitrophenols; Enzyme Activation; Enzyme Inhibitors; Golgi Apparatus; Inositol 1,4,5-Trisphosphate; Isoenzymes; Leukemia, Basophilic, Acute; Mast Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptors, IgE; Serum Albumin, Bovine; Tumor Cells, Cultured; Type C Phospholipases; Wortmannin | 1998 |
Src homology-2 domains protect phosphotyrosyl residues against enzymatic dephosphorylation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Binding, Competitive; Blood Proteins; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glutathione Transferase; Inositol 1,4,5-Trisphosphate; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; src Homology Domains; src-Family Kinases; Structure-Activity Relationship | 1998 |
Dietary fish oil appears to prevent the activation of phospholipase C-gamma in lymphocytes.
Topics: Animals; Coconut Oil; Concanavalin A; Dietary Fats, Unsaturated; Enzyme Activation; Fatty Acids, Essential; Fish Oils; gamma-Linolenic Acid; Inositol 1,4,5-Trisphosphate; Linoleic Acids; Lymphocytes; Male; Oenothera biennis; Olive Oil; Phosphatidylinositol 4,5-Diphosphate; Phosphotyrosine; Plant Oils; Rats; Rats, Inbred Lew; Safflower Oil; Spleen; Type C Phospholipases | 1998 |
Lyn dissociation from phosphorylated Fc epsilon RI subunits: a new regulatory step in the Fc epsilon RI signaling cascade revealed by studies of Fc epsilon RI dimer signaling activity.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Calcium Signaling; Cell Membrane; Cross-Linking Reagents; Cytoskeleton; Dimerization; Enzyme Activation; Enzyme Induction; Inositol 1,4,5-Trisphosphate; Isoenzymes; Leukemia, Basophilic, Acute; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Isoforms; Rats; Receptors, IgE; Serotonin; Signal Transduction; src-Family Kinases; Tumor Cells, Cultured | 1999 |
Inhibition of phosphatidylserine synthesis during Jurkat T cell activation. The phosphatase inhibitor, sodium ortho-vanadate bypasses the CD3/T cell receptor-induced second messenger signaling pathway.
Topics: Antibodies, Monoclonal; Calcium; Calcium Signaling; Calcium-Transporting ATPases; CD3 Complex; Cytosol; Diglycerides; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphatidylserines; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Receptors, Antigen, T-Cell; Second Messenger Systems; Substrate Specificity; T-Lymphocytes; Vanadates | 2000 |
p110beta and p110delta phosphatidylinositol 3-kinases up-regulate Fc(epsilon)RI-activated Ca2+ influx by enhancing inositol 1,4,5-trisphosphate production.
Topics: Animals; Antibodies; Calcium; Cloning, Molecular; Cross-Linking Reagents; Enzyme Activation; Heparin; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Mice; Microinjections; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphoric Monoester Hydrolases; Phosphotyrosine; Rats; Receptors, IgE; Recombinant Proteins; Tumor Cells, Cultured; Type C Phospholipases; Up-Regulation | 2001 |
Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
Topics: Astrocytoma; Calcium; Carbachol; Cell Line, Tumor; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Receptor Substrate Proteins; Ionomycin; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Muscarinic; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma1.
Topics: Adaptor Proteins, Signal Transducing; Calcium; Cell Line; Epidermal Growth Factor; Gene Expression; GRB2 Adaptor Protein; Humans; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein Binding; ras Proteins; RNA, Small Interfering; Signal Transduction; Transfection; Type C Phospholipases; Tyrosine | 2005 |
A function for tyrosine phosphorylation of type 1 inositol 1,4,5-trisphosphate receptor in lymphocyte activation.
Topics: Animals; B-Lymphocytes; Calcium; Chickens; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Jurkat Cells; Lymphocyte Activation; Membrane Microdomains; NFATC Transcription Factors; Phosphorylation; Phosphotyrosine; Protein Transport; Receptors, Antigen, T-Cell; T-Lymphocytes | 2007 |
Cross-linking of FcepsilonRI causes Ca2+ mobilization via a sphingosine kinase pathway in a clathrin-dependent manner.
Topics: Animals; Calcium Signaling; Cell Degranulation; Cell Line; Chlorpromazine; Clathrin Heavy Chains; Coated Pits, Cell-Membrane; Cross-Linking Reagents; Enzyme Activation; Gene Knockdown Techniques; Inositol 1,4,5-Trisphosphate; Mast Cells; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Rats; Receptors, IgE | 2009 |