phosphotyrosine has been researched along with genistein in 201 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 159 (79.10) | 18.2507 |
| 2000's | 38 (18.91) | 29.6817 |
| 2010's | 4 (1.99) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bixby, JL; Jhabvala, P | 1 |
| Andersson, LC; Heiskala, M; Mustelin, T; Ståhls, A | 1 |
| Benhamou, M; Gutkind, JS; Robbins, KC; Siraganian, RP; Stephan, V | 1 |
| Coggeshall, KM; Fukamachi, H; Inagaki, N; Ishizaka, K; Ishizaka, T; Kawakami, T; Takei, M | 1 |
| Akimaru, K; Inoue, M; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T | 1 |
| Colamonici, OR; Platanias, LC | 1 |
| Dotto, GP; Filvaroff, E; Stern, DF | 1 |
| Dhar, A; Paul, AK; Shukla, SD | 1 |
| Clark, EA; Deans, J; Draves, K; Lane, PJ; Ledbetter, JA; McConnell, FM; Schieven, GL | 1 |
| Nakajima, K; Wall, R | 1 |
| Daibata, M; Humphreys, RE; Mellinghoff, I; Sairenji, T; Takagi, S | 1 |
| Daibata, M; Humphreys, RE; Last, TJ; Parker, DC; Sairenji, T; Takagi, S | 1 |
| Druker, B; Griffin, JD; Ikeda, H; Ishikawa, J; Kanakura, Y; Kanayama, Y; Kitayama, H; Kuriu, A; Nishiura, T; Yagura, H | 1 |
| Igarashi, M; Komiya, Y | 1 |
| Borel, JP; Garnotel, R; Haye, B; Monboisse, JC; Randoux, A | 1 |
| Bolen, J; Jin, J; Jun, X; Kurosaki, T; Luben, R; Morgan, A; Takata, M; Uckun, FM | 1 |
| Delafontaine, P; Rao, GN; Runge, MS | 1 |
| Baenziger, NL; Dalemar, LR; Jong, YJ; Wilhelm, B | 1 |
| Beauchemin, C; Chamberland, C; Marceau, N; Potworowski, EF | 1 |
| Keast, JR; Manley, SW; Yap, AS | 1 |
| Kanaide, H; Kobayashi, S; Nishimura, J | 1 |
| Goodwyn, D; Itaya, T; Kawamura, K; Miyagishima, T; Miyazaki, T; Okabe, M; Sakurada, K; Shoji, M; Uehara, M; Vogler, WR | 1 |
| Anel, A; Kleinfeld, AM; Richieri, GV | 1 |
| Danaher, M; Fallon, RJ; Saxena, A; Saylors, RL | 1 |
| Hagmann, W | 1 |
| Biegelmann, E; Gerisch, G; Humbel, B; Jungbluth, A; Schweiger, A; von Arnim, V | 1 |
| Faris, M; Fu, SM; Gaskin, F; Parsons, JT | 1 |
| Della Bianca, V; Donini, M; Dusi, S; Gandini, G; Rossi, F | 1 |
| Hall, A; Ridley, AJ | 1 |
| Della Bianca, V; Donini, M; Dusi, S; Rossi, F | 1 |
| Hall, CL; Lange, LA; Turley, EA; Wang, C | 1 |
| Ito, T; Jagus, R; May, WS | 1 |
| de Juan, E; Koroma, BM | 2 |
| Finlay, BB; Foubister, V; Rosenshine, I; Ruschkowski, S | 1 |
| Eguchi, K; Kawabe, Y; Migita, K; Mizokami, A; Nagataki, S; Tsukada, T | 1 |
| Herberman, RB; Lin, WC; Rabinowich, H; Whiteside, TL | 1 |
| Abboud, HE; Biswas, P; Choudhury, GG; Grandaliano, G | 1 |
| Huang, TS; Kuo, ML; Lin, JK; Yang, NC | 1 |
| Jones, PM; Persaud, SJ | 1 |
| Bayna, EM; Cheresh, DA; Klemke, RL; Yebra, M | 1 |
| Blaser, K; Green, DR; Simon, HU; Yousefi, S | 1 |
| Carter, V; Gale, M; Parsons, M | 1 |
| Bissell, MJ; Desprez, PY; Roskelley, CD | 1 |
| Chess, PR; Finkelstein, JN; Ryan, RM | 1 |
| Ali, JY; Smalheiser, NR | 1 |
| Carpenter, G; McCollum, GW; Polk, DB | 1 |
| Huang, CK; Liang, L | 1 |
| Chang, NS | 1 |
| Corvaia, N; Coutant, KD; Ryder, NS | 1 |
| Kumar, R; Shrivastava, A; Sodhi, A | 1 |
| Cuveele, JF; de Witte, PA; Merlevede, WJ; Vandenheede, JR | 1 |
| Bittorf, T; Busfield, SJ; Callus, B; Cull, VS; Klinken, SP; Tilbrook, PA | 1 |
| Cheung, PY; Dackiw, AP; Fingerote, R; Levy, GA; Nathens, AB; Rotstein, OD; Zakrzewski, K | 1 |
| Di Salvo, J; Semenchuk, LA | 1 |
| Fuller, GM; Wang, Y | 1 |
| Daniel, N; Djiane, J; Dufy, B; Prevarskaya, NB; Skryma, RN; Vacher, P | 1 |
| Chang, P; Greenberg, S; Silverstein, SC | 1 |
| Koide, Y; Ryu, K; Yamashita, Y; Yoshida, TO | 1 |
| Hall, FL; O'Neill, K; Torres, M | 1 |
| Amino, N; Nishiyama, S; Tada, H; Takada, K; Takano, T | 1 |
| Kumada, T; Miyata, H; Nozawa, Y | 1 |
| Colasanto, JM; Gomez-Cambronero, J; Huang, CK; Sha'afi, RI | 1 |
| Buchholz, MJ; Kim, YH; Nordin, AA | 1 |
| Autieri, MV; Coffman, FD; Cohen, S; Fresa, KL; Georgoff, I | 1 |
| Lee, KM; Toscas, K; Villereal, ML | 1 |
| Edashige, K; Sato, EF; Takehara, Y; Utsumi, K; Watanabe, Y | 1 |
| Lee, GM; Maness, PF; Miller, DR | 1 |
| Mendoza, C; Moos, J; Tesarik, J | 1 |
| Hirai, K; Koike, T; Morita, Y; Nozawa, Y | 1 |
| Bongrand, P; Bouhamdan, M; Capo, C; Huang, CK; Mege, JL; Sanguedolce, MV | 1 |
| Di Salvo, J; Lauer, J; Semenchuk, LA | 1 |
| Farndale, RW; Sage, SO; Sargeant, P | 1 |
| Kitamura, N; Komada, M | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| de Jonge, HR; Edixhoven, MJ; Tertoolen, LG; Tilly, BC; van den Berghe, N | 1 |
| Goldberg, DJ; Wu, DY | 1 |
| Greenwel, P; Hu, W; Kohanski, RA; Ramirez, F | 1 |
| Burns, DM; Kawase, T; Ogata, S; Orikasa, M | 1 |
| Kabouridis, PS; McGuire, KL; Stanners, J; Tsoukas, CD | 1 |
| Hallett, MB; Hiscox, S; Jiang, WG; Mansel, RE; Nakamura, T; Puntis, MC; Singhrao, SK | 1 |
| Bronte, V; Collavo, D; Macino, B; Mandruzzato, S; Rosato, A; Zambon, A; Zanovello, P | 1 |
| Akedo, H; Imamura, F; Iwasaki, T; Komagome, R; Mukai, M; Shinkai, K; Yoshioka, K | 1 |
| Bowser, JM; Cohen, ME; Donowitz, M; Khurana, S; Levine, SA; Nath, SK; Tse, CM | 1 |
| Cheng, LY; Mack, P; Wang, DF; Yang, EB | 1 |
| Andersson, T; Eckerdal, J; Sjölander, A; Zheng, L | 1 |
| Aussel, C; Breittmayer, JP; Marhaba, R; Mary, F; Pelassy, C; Stanescu, AT | 1 |
| Hall, CF; Kusner, DJ; Schlesinger, LS | 1 |
| Geibel, J; Sumpio, BE; Yano, Y | 1 |
| Chilvers, ER; Dransfield, I; Hannah, S; Haslett, C; Lawson, MF; Sethi, T; Tallett, A | 1 |
| Puceat, M; Vassort, G | 1 |
| Jänne, OA; Palvimo, JJ; Reinikainen, P | 1 |
| Kunz, B; Kunz, S; Sonderegger, P; Ziegler, U | 1 |
| Chap, H; Cossart, P; Ireton, K; Kasuga, M; Ogawa, W; Payrastre, B; Sakaue, H | 1 |
| Coggeshall, KM; Gulbins, E; Lau, SM; Schlottmann, KE | 1 |
| Marton, LS; Weir, BK; Zhang, H | 1 |
| Bonjour, JP; Caverzasio, J; Palmer, G | 1 |
| Blazer-Yost, BL; Johnson, M; Lee, S; Record, RD | 1 |
| Assreuy, J; Borges, VM; Cunha e Silva, NL; de Souza, W; Martiny, A; Meyer-Fernandes, JR; Vannier-Santos, MA | 1 |
| Ahmad, MB; Devi, KU; Shivaji, S | 1 |
| Gunst, SJ; Pavalko, FM; Wang, Z | 1 |
| Carrera, A; Gerton, GL; Kopf, GS; Moos, J; Moss, SB; Ning, XP; Tesarik, J | 1 |
| Kimura, H | 1 |
| Petryniak, MA; Slack, BE; Wurtman, RJ | 1 |
| Henderson, GB; Saxena, M | 1 |
| Higashida, H; Kimura, Y; Taketo, M; Yokoyama, S | 1 |
| Billings, RE; Collier, JM; Miller, DR | 1 |
| DeFranco, DB; Liu, J; Yang, J | 1 |
| Cooper, V; Manley, SW; Stevenson, BR; Yap, AS | 1 |
| Inoue, T; Itoh, H; Kume, S; Mikoshiba, K; Nagao, M; Nakanishi, S; Sekiyama, N; Umemori, H; Yamamoto, T | 1 |
| Rikihisa, Y; Zhang, Y | 1 |
| Chang, HC; Lee, SC; Yang, SD | 1 |
| He, J; Oleinick, NL; Xue, LY | 1 |
| Ito, Y; Nakashima, S; Nozawa, Y | 1 |
| Luk, JM; Wong, WS | 1 |
| Goyal, RK; Hirano, I; Kakkar, R; Saha, JK; Szymanski, PT | 1 |
| Bannerman, DD; Goldblum, SE | 1 |
| Chen, D; Earp, HS; Elmendorf, JS; Li, X; Olson, AL; Pessin, JE | 1 |
| Dumitrescu, A; Hedin, U; Roy, J; Thyberg, J; Tran, PK | 1 |
| Chien, S; Hu, YL; Hunter, T; Jalali, S; Kim, M; Li, S; Schlaepfer, DD; Shyy, JY | 1 |
| Abrams, JT; Yassin, RR | 1 |
| Di Salvo, J; Raatz Nelson, S | 1 |
| Arai, T; Bulkley, GB; Goldschmidt-Clermont, PJ; Kelly, SA; Milliken, EE; Smith, EH | 1 |
| Kuan, CY; Lee, SC; Wen, ZD; Yang, SD | 1 |
| Carr, BI; Ni, R; Nishikawa, Y | 1 |
| Fukamachi, H; Kawakami, T; Nakahata, T; Suzuki, H; Takei, M; Yanagida, M | 1 |
| Becker, D; Brand, P; Enk, AH; Jonuleit, H; Knop, J; Kühn, U; Saloga, J; van Brandwijk-Petershans, R; Willemsen, J | 1 |
| Isamida, T; Omata, Y; Saito, A; Shimazaki, K; Suzuki, N; Tanaka, T; Yamauchi, K | 1 |
| Carrel, S; Hartmann, RR; Lejeune, FJ; Rimoldi, D | 1 |
| Becker, LE; Erclik, T; Man, HY; Wang, YT | 1 |
| Collares-Buzato, CB; Hirst, BH; Jepson, MA; Simmons, NL | 1 |
| Carbajal, JM; Schaeffer, RC | 1 |
| Menon, KP; Zinn, K | 1 |
| Bozza, PT; Cassara, J; Weller, PF; Yu, W | 1 |
| Goldblum, SE; Wang, P; Young, BA | 1 |
| Arruda, JA; Cardoso, LR; Qiu, YY; Ruiz, OS | 1 |
| Berg, G; Grenegård, M; Nilsson, UK; Svensson, SP | 1 |
| Lu, Z; McGilvray, ID; Rotstein, OD; Wei, AC | 1 |
| Fernandis, AZ; Subrahmanyam, G | 1 |
| DeWald, DB; Forney, JR; Healey, MC; Speer, CA; Yang, S | 1 |
| Kumano, T; Kuriyama, M; Mutoh, T; Nakagawa, H | 2 |
| Hill, EM; Williams-Bouyer, NM | 1 |
| Brennan, H; Smith, S; Stoker, A | 1 |
| Ando, M; Mera, A; Suda, T; Suga, M; Yamaguchi, N | 1 |
| Gómez-Muñoz, A; Hundal, R; O'Brien, L; Steinbrecher, UP | 1 |
| Bedoya, FJ; Camacho, MJ; Carballo, M; Conde, J; Conde, M; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Sobrino, F | 1 |
| Dubois, M; Gilbert, M; Lagarde, M; Meskini, N; Némoz, G; Prigent, AF; Zakaroff-Girard, A | 1 |
| Kimura, K; Kishino, M; Mune, M; Nishide, I; Sonobe, M; Tone, Y; Yamada, Y; Yukawa, S | 1 |
| Holly, JM; Mihai, R; Stewart, CE | 1 |
| Kapus, A; Rizoli, SB; Rotstein, OD | 1 |
| Goode, CA; Lambert, CC; Lucio-Gough, LM; Mckinney, K; Robert, LK | 1 |
| Anderson, RG; Liu, P | 1 |
| Marre, R; Susa, M | 1 |
| Ahmad, A; Gorra, VA; Heffernan, CC; Weeks, BS; White, LE; Wilson, PJ | 1 |
| Béguin, P; Carranza, ML; Caverzasio, J; Favre, H; Féraille, E; Geering, K; Gonin, S; Martin, PY; Pedemonte, C; Rousselot, M | 1 |
| Cruz, M; Eneroth, P; Sidén, A; Vargas, VI; Yakisich, JS | 1 |
| Altura, BM; Altura, BT; Yang, ZW | 1 |
| Chap, H; Laffargue, M; Payrastre, B; Peres, C; Raynal, P; Roche, S; Wetzker, R; Yart, A | 1 |
| Cammarata, G; Cervello, M; Gambino, R; Isola, G; Sanfilippo, R; Scalia, G; Virruso, L | 1 |
| Braun, L; Chase, CC; Frew, T; Hurley, DJ; Rowland, RR; Shaw, AM | 1 |
| Fischer, W; Gerland, E; Haas, R; Odenbreit, S; Püls, J; Sedlmaier, B | 1 |
| Akiyama, K; Fukai, F; Goto, S; Goto, T; Kamiya, S; Katayama, T; Ohwaki, T | 1 |
| Araki, Y; Sendo, F; Yu, Y | 1 |
| Heads, RJ; Marber, MS; Mockridge, JW | 1 |
| Alexander, B; Alexander, JS; Coe, LL; Flores, SC; Joh, T; Oshima, T; Park, JH; Vaitaitis, G; Zhu, Y | 1 |
| Dantin, F; Dubois, F; Mazière, C; Mazière, J; Santus, R | 1 |
| Gong, H; Payne, J; Trinkaus-Randall, V | 1 |
| Emmanouel, DS; Gravanis, A; Papakonstanti, EA; Stournaras, C | 1 |
| Boland, R; Buitrago, C; De Boland, AR; Morelli, S; Vazquez, G | 1 |
| Eriksson, JW; Yu, ZW | 1 |
| Bae, SS; Choi, I; Lee, YH; Ryu, SH; Seo, JK; Suh, PG | 1 |
| Appleyard, SM; Chavkin, C; McLaughlin, JP | 1 |
| D'Adamo, MC; Imbrici, P; Pessia, M; Tucker, SJ | 1 |
| Berk, BC; Chen, K; Keaney, JF; Vita, JA | 1 |
| Herrera, R; Petruzzelli, L; Takami, M | 1 |
| Li, H; Wong, WS | 1 |
| Hidari, KI; Kimura, M; Miyamoto, D; Suzuki, T; Suzuki, Y | 1 |
| Anderson, CS; Brittain, JE; Mlinar, KJ; Orringer, EP; Parise, LV | 1 |
| An, GJ; Ando, A; Cao, J; Chang, KY; Cooney, MJ; de Juan, E; Melia, M; Nakajima, M; Tu, AH | 1 |
| Conte, MA; Mazière, C; Mazière, JC | 1 |
| Bompadre, MB; Coso, OA; Fernández, GC; Gómez, S; Isturiz, MA; Palermo, MS; Rosa, FA; Rubel, C | 1 |
| Chen, A; Hoffman-Kim, D; Jay, DG; Kerner, JA; Wang, TF; Xu, A | 1 |
| Snell, WJ; Wang, Q | 1 |
| Arif, A; Dutta-Gupta, A; Scheller, K | 1 |
| Adegunloye, BJ; Camper, EV; Moreland, RS; Su, X | 1 |
| Kim, CH; Kim, HM; Park, SY; Park, WH | 1 |
| Fukuda, M; Longnecker, R | 1 |
| Chen, ST; Hsu, JR; Huang, HJ; Hung, SP; Lo, CP; Wang, JP | 1 |
| Pelletier, RM; Solinet, S; Vitale, ML; Zheng, G | 1 |
| Feng-Ling, Y; Hsue-Yin, H; Hung-Jen, L; Jeng-Woei, L; Meng-Jiun, L; Ping-Yuan, L; Wen-Ling, S | 1 |
| Abdullah, LH; Davis, CW | 1 |
| Chen, CS; Fong, JH; Khan, M; Ng, AP; Nin, DS; Venkataraman, D | 1 |
| Janssen, LJ; Lippton, H; Liu, C; Tazzeo, T | 1 |
| Lau, CP; Li, GR; Tse, HF; Wang, Y; Zhang, DY | 1 |
| Bui, L; Konradsson, P; Magnusson, KE; Vikström, E | 1 |
| Attias, M; Lopes-Bezerra, LM; Loureiro y Penha, CV; Mattos-Guaraldi, AL; Nagao, PE; Santos, GS; Silva-Filho, FC | 1 |
| Cao, Y; Chen, NP; He, GW; He, QY; Xiao, CL; Yan, GR; Yin, XF | 1 |
| Aifa, S; Elloumi-Mseddi, J; Jellali, K | 1 |
| Hu, M; Li, YZ; Pei, BL; Zhang, LF | 1 |
| Deng, XL; Li, GR; Liu, YG; She, G; Song, Z; Sun, HY; Wang, Y; Xiao, GS | 1 |
1 review(s) available for phosphotyrosine and genistein
| Article | Year |
|---|---|
Inhibition of protein tyrosine phosphorylation in endothelial cells: relationship to antiproliferative action of genistein.
Topics: Animals; Aorta; Cattle; Cell Division; Cell Survival; Cells, Cultured; DNA; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Genistein; Isoflavones; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases | 1997 |
200 other study(ies) available for phosphotyrosine and genistein
| Article | Year |
|---|---|
Inhibition of tyrosine phosphorylation potentiates substrate-induced neurite growth.
Topics: Animals; Brain; Catechols; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Chick Embryo; Culture Media; Extracellular Matrix Proteins; Genistein; Isoflavones; Nerve Tissue Proteins; Neurites; Neurons; Nitriles; Phenols; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; Tyrosine; Tyrphostins; Vanadates | 1992 |
Activation of natural killer cells via the Fc gamma RIII (CD16) requires initial tyrosine phosphorylation.
Topics: Antibody-Dependent Cell Cytotoxicity; Antigens, Differentiation; Cytotoxicity, Immunologic; Genistein; Inositol Phosphates; Isoflavones; Killer Cells, Natural; Lymphocyte Activation; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fc; Receptors, IgG; Signal Transduction; Tyrosine | 1992 |
Fc epsilon RI-induced protein tyrosine phosphorylation of pp72 in rat basophilic leukemia cells (RBL-2H3). Evidence for a novel signal transduction pathway unrelated to G protein activation and phosphatidylinositol hydrolysis.
Topics: 3T3 Cells; Animals; Antigens, Differentiation, B-Lymphocyte; Carbachol; Cell Line; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoglobulin E; Inositol Phosphates; Isoflavones; Kinetics; Leukemia, Basophilic, Acute; Mice; Models, Biological; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Fc; Receptors, IgE; Receptors, Muscarinic; Signal Transduction; Transfection; Type C Phospholipases; Tyrosine | 1992 |
Tyrosine phosphorylation is required for mast cell activation by Fc epsilon RI cross-linking.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cross-Linking Reagents; Genistein; Histamine Release; Immunoglobulin E; Inositol 1,4,5-Trisphosphate; Isoflavones; Mast Cells; Mice; Mice, Inbred CBA; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fc; Receptors, IgE; Signal Transduction; Type C Phospholipases; Tyrosine | 1992 |
Role of tyrosyl phosphorylation in neutrophil priming by tumor necrosis factor-alpha and granulocyte colony stimulating factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Blotting, Western; Cell Membrane; Cytosol; Genistein; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Isoflavones; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 1992 |
Interferon alpha induces rapid tyrosine phosphorylation of the alpha subunit of its receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Western; Dose-Response Relationship, Drug; Genistein; Humans; Interferon Type I; Isoflavones; Isoquinolines; Kinetics; Macromolecular Substances; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Interferon; Recombinant Proteins; Time Factors; Tumor Cells, Cultured; Tyrosine | 1992 |
Tyrosine phosphorylation is an early and specific event involved in primary keratinocyte differentiation.
Topics: Animals; Blotting, Western; Calcium; Cell Differentiation; Cytoskeleton; Cytosol; Genistein; Isoflavones; Keratinocytes; Mice; Mice, Inbred Strains; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Transglutaminases; Tyrosine | 1990 |
Platelet-activating factor stimulation of tyrosine kinase and its relationship to phospholipase C in rabbit platelets: studies with genistein and monoclonal antibody to phosphotyrosine.
Topics: Animals; Antibodies, Monoclonal; Blood Platelets; Blotting, Western; Flavonoids; Genistein; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tritium; Type C Phospholipases; Tyrosine | 1990 |
The role of tyrosine phosphorylation in signal transduction through surface Ig in human B cells. Inhibition of tyrosine phosphorylation prevents intracellular calcium release.
Topics: Aluminum; Aluminum Compounds; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Benzoquinones; Calcium; CD40 Antigens; Cell Line; Cross-Linking Reagents; Fluorides; Genistein; Humans; Immunoglobulin M; Isoflavones; Lactams, Macrocyclic; Models, Biological; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Receptors, Antigen, B-Cell; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine | 1991 |
Interleukin-6 signals activating junB and TIS11 gene transcription in a B-cell hybridoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; B-Lymphocytes; Cycloheximide; DNA-Binding Proteins; Gene Expression Regulation; Genistein; Hybridomas; Immediate-Early Proteins; In Vitro Techniques; Interleukin-6; Isoflavones; Isoquinolines; Lymphocyte Activation; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Tristetraprolin; Tyrosine | 1991 |
Effect of genistein, a tyrosine kinase inhibitor, on latent EBV activation induced by cross-linkage of membrane IgG in Akata B cells.
Topics: Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Line; Cross-Linking Reagents; DNA-Binding Proteins; Gene Expression Regulation, Viral; Genistein; Herpesvirus 4, Human; Humans; Immunoglobulin G; In Vitro Techniques; Isoflavones; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor Aggregation; Receptors, Antigen, B-Cell; Trans-Activators; Tyrosine; Viral Proteins | 1991 |
Intracellular localization of tyrosine kinase substrates beneath crosslinked surface immunoglobulins in B cells.
Topics: Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Line; Cross-Linking Reagents; Cytoplasm; Fluorescent Antibody Technique; Genistein; Humans; Immunoglobulin G; Isoflavones; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; Tyrosine | 1991 |
Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product.
Topics: Blotting, Northern; Cell Division; Gene Expression; Genistein; Hematopoietic Cell Growth Factors; Humans; Immunologic Techniques; Isoflavones; Leukemia, Myeloid; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Recombinant Proteins; Stem Cell Factor; Tumor Cells, Cultured; Tyrosine | 1991 |
Tyrosine phosphorylation and immunodetection of vinculin in growth cone particle (GCP) fraction and in GCP-cytoskeletal subfractions.
Topics: Animals; Antibodies, Monoclonal; Brain; Calcium; Cytoskeleton; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fetus; Genistein; Isoflavones; Molecular Weight; Neurons; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Synaptosomes; Tyrosine; Vinculin | 1991 |
The binding of type I collagen to lymphocyte function-associated antigen (LFA) 1 integrin triggers the respiratory burst of human polymorphonuclear neutrophils. Role of calcium signaling and tyrosine phosphorylation of LFA 1.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antigens, CD; Calcium; CD18 Antigens; Cell Adhesion; Collagen; Cytosol; Enzyme Inhibitors; Genistein; Humans; Immunoglobulin G; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Integrin alpha1; Isoflavones; Kinetics; Lymphocyte Function-Associated Antigen-1; Molecular Sequence Data; Neutrophils; Oligopeptides; Peptide Fragments; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Superoxides | 1995 |
Exposure of B-lineage lymphoid cells to low energy electromagnetic fields stimulates Lyn kinase.
Topics: Amino Acid Sequence; B-Lymphocytes; Benzoquinones; Cell Line; Electromagnetic Fields; Enzyme Inhibitors; Enzyme Precursors; Genistein; Humans; Intracellular Signaling Peptides and Proteins; Isoflavones; Lactams, Macrocyclic; Molecular Sequence Data; Myelin Basic Protein; Peptide Fragments; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Syk Kinase | 1995 |
Thrombin stimulates phosphorylation of insulin-like growth factor-1 receptor, insulin receptor substrate-1, and phospholipase C-gamma 1 in rat aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Benzoquinones; Cells, Cultured; DNA; DNA Replication; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Insulin Receptor Substrate Proteins; Isoenzymes; Isoflavones; Lactams, Macrocyclic; Male; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Rifabutin; Thrombin; Type C Phospholipases | 1995 |
Human bradykinin B2 receptors isolated by receptor-specific monoclonal antibodies are tyrosine phosphorylated.
Topics: Antibodies, Monoclonal; Bradykinin; Cells, Cultured; Chromatography, Affinity; Dinoprostone; Genistein; Humans; In Vitro Techniques; Isoflavones; Phosphotyrosine; Receptors, Bradykinin; Signal Transduction; Tyrosine | 1993 |
Up-regulation of a thymic epithelial ligand after contact with thymocytes.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Down-Regulation; Epithelial Cells; Genistein; In Vitro Techniques; Isoflavones; Ligands; Phosphotyrosine; Signal Transduction; T-Lymphocytes; Thymus Gland; Tyrosine; Up-Regulation | 1994 |
Thyroid cell spreading and focal adhesion formation depend upon protein tyrosine phosphorylation and actin microfilaments.
Topics: Actin Cytoskeleton; Actins; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Colchicine; Cytochalasin B; Fluorescent Antibody Technique; Genistein; Heparin; Isoflavones; Kinetics; Phosphotyrosine; Protein-Tyrosine Kinases; Swine; Thyroid Gland; Tyrosine; Vinculin | 1994 |
Cytosolic Ca2+ transients are not required for platelet-derived growth factor to induce cell cycle progression of vascular smooth muscle cells in primary culture. Actions of tyrosine kinase.
Topics: Angiotensin II; Animals; Caffeine; Calcium; Cell Cycle; Cells, Cultured; Cytosol; Genistein; Isoflavones; Male; Muscle, Smooth, Vascular; Nitriles; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Ryanodine; Second Messenger Systems; Signal Transduction; Tyrosine | 1994 |
Effect of herbimycin A, an inhibitor of tyrosine kinase, on protein tyrosine kinase activity and phosphotyrosyl proteins of Ph1-positive leukemia cells.
Topics: Antibiotics, Antineoplastic; Benzoquinones; Fusion Proteins, bcr-abl; Genistein; Humans; Isoflavones; Lactams, Macrocyclic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasm Proteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tumor Cells, Cultured; Tyrosine | 1994 |
A tyrosine phosphorylation requirement for cytotoxic T lymphocyte degranulation.
Topics: Animals; Arsenicals; Calcium; Clone Cells; Concanavalin A; Fatty Acids, Nonesterified; Genistein; Ionomycin; Isoflavones; Kinetics; Lymphocyte Activation; Mice; Molecular Weight; Oleic Acid; Oleic Acids; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Defective asialoglycoprotein receptor endocytosis mediated by tyrosine kinase inhibitors. Requirement for a tyrosine in the receptor internalization signal.
Topics: Adenosine Triphosphate; Alkaloids; Asialoglycoprotein Receptor; Carcinoma, Hepatocellular; Catechols; Cell Line; Endocytosis; Genistein; Humans; Isoflavones; Kinetics; Liver Neoplasms; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; Staurosporine; Transferrin; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line.
Topics: Animals; Benzoquinones; Catechols; Cell Division; Cell Line; Genistein; Interleukin-3; Interleukin-4; Ionomycin; Isoflavones; Kinetics; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Leukotrienes; Mast-Cell Sarcoma; Mice; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Strong increase in the tyrosine phosphorylation of actin upon inhibition of oxidative phosphorylation: correlation with reversible rearrangements in the actin skeleton of Dictyostelium cells.
Topics: Actins; Adenosine Triphosphate; Animals; Arsenicals; Cytoskeleton; Dictyostelium; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Genistein; Growth Inhibitors; Isoflavones; Microscopy, Fluorescence; Oxidative Phosphorylation; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1994 |
CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Benzoquinones; Burkitt Lymphoma; CD40 Antigens; Cell Line; Cell Line, Transformed; Enzyme Precursors; Genistein; Herpesvirus 4, Human; Humans; Intracellular Signaling Peptides and Proteins; Isoflavones; Isoquinolines; Lactams, Macrocyclic; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Weight; Palatine Tonsil; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Quinones; Rifabutin; Sulfonamides; Syk Kinase; Tumor Cells, Cultured; Tyrosine | 1994 |
In human neutrophils the binding to immunocomplexes induces the tyrosine phosphorylation of Fc gamma RII but this phosphorylation is not an essential signal for Fc-mediated phagocytosis.
Topics: Antigen-Antibody Complex; Genistein; Humans; Hydroquinones; In Vitro Techniques; Isoflavones; Neutrophils; Phagocytosis; Phosphorylation; Phosphotyrosine; Receptors, IgG; Tyrosine | 1994 |
Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.
Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Isoflavones; Lysophospholipids; Mice; Models, Biological; Myosins; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1994 |
Tyrosine phosphorylation of phospholipase C-gamma 2 is involved in the activation of phosphoinositide hydrolysis by Fc receptors in human neutrophils.
Topics: Genistein; Humans; Isoenzymes; Isoflavones; Neutrophils; Phosphatidylinositols; Phosphoproteins; Phosphotyrosine; Receptor Aggregation; Receptors, Fc; Signal Transduction; Time Factors; Type C Phospholipases; Tyrosine | 1994 |
Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity.
Topics: Antibodies; Benzoquinones; Carrier Proteins; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Cell Movement; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Hyaluronan Receptors; Hyaluronic Acid; Isoflavones; Lactams, Macrocyclic; Microinjections; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Receptor, Insulin; Receptors, Cell Surface; Receptors, Lymphocyte Homing; Rifabutin; Signal Transduction; Tyrosine; Vinculin | 1994 |
Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase.
Topics: Animals; Cells, Cultured; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Enzymologic; Genistein; Interleukin-3; Isoflavones; Mice; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Biosynthesis; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tyrosine | 1994 |
Phosphotyrosine inhibition and control of vascular endothelial cell proliferation by genistein.
Topics: Animals; Cattle; Cell Division; Cells, Cultured; DNA; Endothelium, Vascular; Fibroblast Growth Factor 2; Genistein; Isoflavones; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Tyrosine | 1994 |
Salmonella typhimurium invasion of epithelial cells: role of induced host cell tyrosine protein phosphorylation.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Epithelium; Genistein; HeLa Cells; Humans; In Vitro Techniques; Isoflavones; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Salmonella Infections; Salmonella typhimurium; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1994 |
Prevention of anti-CD3 monoclonal antibody-induced thymic apoptosis by protein tyrosine kinase inhibitors.
Topics: Animals; Apoptosis; Benzoquinones; CD3 Complex; Clonal Deletion; Dexamethasone; Genistein; Isoflavones; Lactams, Macrocyclic; Mice; Mice, Inbred BALB C; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Quinones; Rifabutin; T-Lymphocyte Subsets; Thymus Gland; Tyrosine | 1994 |
Signaling via CD7 molecules on human NK cells. Induction of tyrosine phosphorylation and beta 1 integrin-mediated adhesion to fibronectin.
Topics: Alkaloids; Amino Acid Sequence; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Calcium; Cell Adhesion; Cytochalasin B; Enzyme Activation; Fibronectins; Genistein; Humans; In Vitro Techniques; Integrins; Isoflavones; Killer Cells, Natural; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fibronectin; Receptors, IgG; Receptors, Immunologic; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Mitogenic signaling of thrombin in mesangial cells: role of tyrosine phosphorylation.
Topics: Benzoquinones; Calcium; Cells, Cultured; Cysteine; DNA; Gene Expression; Genistein; Glomerular Mesangium; Humans; Immunoblotting; Inositol Phosphates; Isoflavones; Lactams, Macrocyclic; Mitogens; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Sulfur Radioisotopes; Thrombin; Tyrosine | 1994 |
Reversion of the transformed phenotypes of v-H-ras NIH3T3 cells by flavonoids through attenuating the content of phosphotyrosine.
Topics: 3T3 Cells; Animals; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chamomile; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Flavonoids; Genes, ras; Genistein; Isoflavones; Kaempferols; Mice; Oils, Volatile; Phenotype; Phosphotyrosine; Plants, Medicinal; Protein-Tyrosine Kinases; Quercetin; Tyrosine | 1994 |
Tyrosine kinase inhibitors inhibit glucose-stimulated insulin secretion.
Topics: Animals; Catechols; Genistein; Glucose; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Isoflavones; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Tyrosine; Tyrphostins | 1994 |
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
Topics: Cell Adhesion; Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Genistein; Glycoproteins; Humans; Insulin-Like Growth Factor I; Integrins; Isoflavones; Kinetics; Naphthalenes; Nitriles; Pancreatic Neoplasms; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vitronectin | 1994 |
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils.
Topics: Apoptosis; Arsenicals; Eosinophils; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Isoflavones; Neutrophils; Phosphoprotein Phosphatases; Phosphotyrosine; Signal Transduction; Tyrosine | 1994 |
Cell cycle-specific induction of an 89 kDa serine/threonine protein kinase activity in Trypanosoma brucei.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Catechols; Cell Cycle; Cell Division; Cycloheximide; DNA; Enzyme Induction; Ethers, Cyclic; Flow Cytometry; Genistein; Isoflavones; Isoquinolines; Molecular Weight; Nitriles; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Denaturation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; S Phase; Staurosporine; Trypanosoma brucei brucei; Tyrosine; Tyrphostins | 1994 |
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.
Topics: Animals; Caseins; Cell Aggregation; Cells, Cultured; Extracellular Matrix; Female; Gene Expression Regulation, Developmental; Genistein; In Vitro Techniques; Integrins; Isoflavones; Mice; Phosphotyrosine; Prolactin; Receptor Aggregation; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1994 |
Tyrosine kinase activity is necessary for growth factor-stimulated rabbit type II pneumocyte proliferation.
Topics: Adenocarcinoma; Animals; Blotting, Western; Catechols; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Isoflavones; Kinetics; Lung; Male; Molecular Weight; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Acute neurite retraction triggered by lysophosphatidic acid: timing of the inhibitory effects of genistein.
Topics: Actins; Animals; Genistein; Glioma; Hybrid Cells; Immunohistochemistry; Isoflavones; Kinetics; Lysophospholipids; Mice; Neurites; Neuroblastoma; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Time Factors; Tyrosine | 1994 |
Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6).
Topics: Animals; Cell Count; Cell Division; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Genistein; Inositol Phosphates; Intestinal Mucosa; Isoenzymes; Isoflavones; Membrane Proteins; Phospholipase C gamma; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Time Factors; Type C Phospholipases; Tyrosine | 1995 |
Tyrosine phosphorylation induced by cross-linking of Fc gamma-receptor type II in human neutrophils.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cross-Linking Reagents; Egtazic Acid; Ethers, Cyclic; Genistein; Humans; Isoflavones; Molecular Sequence Data; Neutrophils; Okadaic Acid; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, IgG; Respiratory Burst; Tyrosine; Virulence Factors, Bordetella | 1995 |
Transforming growth factor-beta 1 induction of novel extracellular matrix proteins that trigger resistance to tumor necrosis factor cytotoxicity in murine L929 fibroblasts.
Topics: Alkaloids; Animals; Catechols; Cell Survival; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Fibroblasts; Genistein; Isoflavones; Kinetics; L Cells; Mice; Nitriles; Phenols; Phosphotyrosine; Protein Kinase Inhibitors; Staurosporine; Transforming Growth Factor beta; Tumor Protein, Translationally-Controlled 1; Tyrosine; Tyrphostins | 1995 |
Bradykinin induces tyrosine phosphorylation of epidermal growth factor-receptor and focal adhesion proteins in human keratinocytes.
Topics: Alkaloids; Bradykinin; Cell Adhesion Molecules; Cell Line; Chromatography, Affinity; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Immunoblotting; Indoles; Isoflavones; Keratinocytes; Maleimides; Molecular Weight; Paxillin; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Bradykinin; Staurosporine; Tyrosine | 1995 |
Cisplatin stimulates protein tyrosine phosphorylation in macrophages.
Topics: Animals; Cell Line; Cisplatin; Enzyme Activation; Fluorescent Antibody Technique; Genistein; Isoflavones; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenols; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1995 |
Analysis of phosphorylhydroxyamino acids present in hydrolyzed cell extracts using dabsyl derivatization.
Topics: Cell Extracts; Chromatography, Thin Layer; Electrophoresis; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; p-Dimethylaminoazobenzene; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Protein-Tyrosine Kinases; Quercetin; Tumor Cells, Cultured; Tyrosine | 1995 |
Amiloride suppresses erythropoietin-induced proliferation and MAP kinase, but potentiates differentiation of J2E cells.
Topics: Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Erythrocytes; Erythropoietin; Genistein; Hemoglobins; Humans; Immunoblotting; Isoflavones; Kinetics; Leucine; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Thymidine; Tyrosine | 1995 |
Induction of macrophage procoagulant activity by murine hepatitis virus strain 3: role of tyrosine phosphorylation.
Topics: Animals; Benzoquinones; Catechols; Cells, Cultured; Female; Genistein; Hepatitis, Viral, Animal; Isoflavones; Kinetics; Lactams, Macrocyclic; Macrophages, Peritoneal; Mice; Murine hepatitis virus; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine; Tyrphostins | 1995 |
Receptor-activated increases in intracellular calcium and protein tyrosine phosphorylation in vascular smooth muscle cells.
Topics: Animals; Calcium; Cells, Cultured; Dogs; Femoral Artery; Fura-2; Genistein; Isoflavones; Muscle, Smooth, Vascular; Nitriles; Phenylephrine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Tyrosine | 1995 |
Interleukin-6 and ciliary neurotrophic factor trigger janus kinase activation and early gene response in rat hepatocytes.
Topics: Acute-Phase Reaction; Animals; Antigens, CD; Ciliary Neurotrophic Factor; Cytokine Receptor gp130; Enzyme Activation; Enzyme Inhibitors; Genes, Immediate-Early; Genes, jun; Genistein; Interleukin-6; Isoflavones; Janus Kinase 1; Janus Kinase 2; Liver; Membrane Glycoproteins; Nerve Tissue Proteins; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Signal Transduction | 1995 |
Role of tyrosine phosphorylation in potassium channel activation. Functional association with prolactin receptor and JAK2 tyrosine kinase.
Topics: Animals; Benzoquinones; CHO Cells; Cricetinae; Enzyme Inhibitors; Genistein; Ion Channel Gating; Isoflavones; Janus Kinase 2; Kinetics; Lactams, Macrocyclic; Membrane Potentials; Patch-Clamp Techniques; Phenols; Phosphorylation; Phosphotyrosine; Potassium Channels; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Quinones; Receptors, Prolactin; Recombinant Proteins; Rifabutin; Signal Transduction; Time Factors; Transfection | 1995 |
Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages.
Topics: Actins; Animals; Female; Fluorescent Antibody Technique; Genistein; In Vitro Techniques; Isoflavones; Macrophages; Mice; Mice, Inbred C57BL; Phagocytosis; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Fc; Tyrosine | 1993 |
Inhibition of tyrosine phosphorylation prevents IFN-gamma-induced HLA-DR molecule expression.
Topics: Benzoquinones; Calcimycin; Calcium; Genistein; HLA-DR Antigens; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Interferon-gamma; Isoflavones; Lactams, Macrocyclic; Nitriles; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Recombinant Proteins; Rifabutin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1993 |
Stimulation of human neutrophils with formyl-methionyl-leucyl-phenylalanine induces tyrosine phosphorylation and activation of two distinct mitogen-activated protein-kinases.
Topics: Amino Acid Sequence; Blotting, Western; Cell Compartmentation; Enzyme Activation; ErbB Receptors; Genistein; Humans; Isoflavones; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Respiratory Burst; Tyrosine | 1993 |
Genistein, a tyrosine kinase inhibitor, blocks the cell cycle progression but not Ca2+ influx induced by BAY K8644 in FRTL-5 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Cell Cycle; DNA; Genistein; Insulin-Like Growth Factor I; Isoflavones; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Thyrotropin; Time Factors; Tyrosine | 1993 |
Involvement of tyrosine phosphorylation in IgE receptor-mediated phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antigens; Basophils; Cinnamates; Enzyme Activation; Genistein; Immunoglobulin E; In Vitro Techniques; Isoflavones; Leukemia, Basophilic, Acute; Phospholipase D; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; Sulfides; Tumor Cells, Cultured; Tyrosine | 1993 |
Direct stimulation by tyrosine phosphorylation of microtubule-associated protein (MAP) kinase activity by granulocyte-macrophage colony-stimulating factor in human neutrophils.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Ion Exchange; Ethers, Cyclic; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Isoflavones; Neutrophils; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine | 1993 |
Murine T-lymphocyte proliferation induced by interleukin 2 correlates with a transient increase in p56lck kinase activity and the tyrosine phosphorylation of a 97-kDa protein.
Topics: Animals; Blotting, Northern; Dose-Response Relationship, Drug; Enzyme Activation; Genes, myc; Genistein; Humans; Interleukin-2; Isoflavones; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Mice; Mice, Inbred C57BL; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; RNA, Messenger; RNA, Ribosomal, 18S; T-Lymphocytes; Thymidine; Tyrosine | 1993 |
A cytosolic activator of DNA replication is tyrosine phosphorylated in its active form.
Topics: Aprotinin; Cytosol; DNA Replication; Dose-Response Relationship, Drug; Flavonoids; Genistein; Humans; In Vitro Techniques; Isoflavones; Kaempferols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Signal Transduction; Tyrosine | 1993 |
Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors.
Topics: Barium; Bradykinin; Calcium; Calcium-Transporting ATPases; Catechols; Cells, Cultured; Fibroblasts; Fura-2; Genistein; Humans; Immunoblotting; Isoflavones; Kinetics; Male; Nitriles; Phosphotyrosine; Protein-Tyrosine Kinases; Skin; Terpenes; Thapsigargin; Tyrosine; Tyrphostins | 1993 |
Reversible priming and protein-tyrosyl phosphorylation in human peripheral neutrophils under hypotonic conditions.
Topics: Amino Acid Sequence; Genistein; Humans; Isoflavones; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmotic Pressure; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Superoxides; Tyrosine | 1993 |
Increased neurite outgrowth induced by inhibition of protein tyrosine kinase activity in PC12 pheochromocytoma cells.
Topics: Adenosine Triphosphate; Animals; Catechols; Cell Differentiation; Cell Division; Electrophoresis, Polyacrylamide Gel; Genistein; Isoflavones; Kinetics; Molecular Weight; Nerve Growth Factors; Neurites; Nitriles; PC12 Cells; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Receptor, trkA; Tyrosine; Tyrphostins; Video Recording | 1993 |
Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm.
Topics: Adenosine Triphosphate; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Genistein; Humans; Isoflavones; Male; Phosphoproteins; Phosphorylation; Phosphotyrosine; Progesterone; Protein-Tyrosine Kinases; Receptors, Progesterone; Serum Albumin, Bovine; Spermatozoa; Tyrosine | 1993 |
Stem cell factor-induced signal transduction in rat mast cells. Activation of phospholipase D but not phosphoinositide-specific phospholipase C in c-kit receptor stimulation.
Topics: Animals; Antigens; Diglycerides; Genistein; Hematopoietic Cell Growth Factors; Isoflavones; Mast Cells; Peritoneal Cavity; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Phosphotyrosine; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Rats; Rats, Wistar; Second Messenger Systems; Secretory Rate; Serotonin; Signal Transduction; Stem Cell Factor; Type C Phospholipases; Tyrosine | 1993 |
Zymosan-induced tyrosine phosphorylations in human monocytes. Role of protein kinase C.
Topics: Catechols; Genistein; Humans; In Vitro Techniques; Isoflavones; Molecular Weight; Monocytes; Naphthalenes; Nitriles; Phosphoproteins; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Tyrosine; Tyrphostins; Vanadium; Zymosan | 1993 |
Vanadate-induced contraction of smooth muscle and enhanced protein tyrosine phosphorylation.
Topics: Animals; Calcium; Genistein; Guinea Pigs; Intestine, Large; Isoflavones; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myosins; Peptides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1993 |
ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Blood Proteins; Calcium; Calcium-Transporting ATPases; Cinnamates; Fluorescent Dyes; Fura-2; Genistein; Humans; In Vitro Techniques; Isoflavones; Kinetics; Phosphotyrosine; Protein-Tyrosine Kinases; Terpenes; Thapsigargin; Time Factors; Tyrosine | 1993 |
The cell dissociation and motility triggered by scatter factor/hepatocyte growth factor are mediated through the cytoplasmic domain of the c-Met receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Aggregation; Cell Movement; Cell Size; Epidermal Growth Factor; ErbB Receptors; Genistein; Hepatocyte Growth Factor; Isoflavones; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Recombinant Fusion Proteins; Signal Transduction; Tyrosine | 1993 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.
Topics: Benzoquinones; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Genistein; Humans; Hypotonic Solutions; Intestines; Iodides; Isoflavones; Kinetics; Lactams, Macrocyclic; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Rubidium; Tyrosine; Vanadates; Water-Electrolyte Balance | 1993 |
Regulated tyrosine phosphorylation at the tips of growth cone filopodia.
Topics: Animals; Aplysia; Cytoskeleton; Genistein; Hemolymph; Isoflavones; Neurons; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1993 |
Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Collagen; Enzyme Inhibitors; Ethers, Cyclic; Fetus; Fibroblasts; Gene Expression; Genistein; Humans; Isoflavones; Isoquinolines; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphotyrosine; Piperazines; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Skin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vanadates | 1995 |
Protein tyrosine phosphorylation induced by epidermal growth factor and insulin-like growth factor-I in a rat clonal dental pulp-cell line.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Dental Pulp; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Isoflavones; Mice; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor, IGF Type 1; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling.
Topics: Antibodies, Monoclonal; Base Sequence; Blotting, Western; Cell Line; Cell Membrane; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Isoflavones; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Transfection | 1995 |
Induction of tyrosine phosphorylation and translocation of ezrin by hepatocyte growth factor/scatter factor.
Topics: Actins; Cell Compartmentation; Cell Membrane; Cytoskeletal Proteins; Enzyme Inhibitors; Genistein; Hepatocyte Growth Factor; Humans; Immunohistochemistry; Isoflavones; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 1995 |
Protein tyrosine kinases and phosphatases control apoptosis induced by extracellular adenosine 5'-triphosphate.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Cell Line; DNA Damage; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Homeostasis; Isoflavones; Leukemia L1210; Mast-Cell Sarcoma; Mice; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Vanadates | 1996 |
rho-Mediated protein tyrosine phosphorylation in lysophosphatidic-acid-induced tumor-cell invasion.
Topics: Animals; Cell Adhesion Molecules; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; GTP-Binding Proteins; Isoflavones; Liver Neoplasms, Experimental; Lysophospholipids; Neoplasm Invasiveness; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; rho GTP-Binding Proteins; Signal Transduction; Tumor Cells, Cultured | 1996 |
Brush border phosphatidylinositol 3-kinase mediates epidermal growth factor stimulation of intestinal NaCl absorption and Na+/H+ exchange.
Topics: Androstadienes; Animals; Cell Line; Cell Polarity; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Glucose; Humans; Intestinal Absorption; Intestinal Mucosa; Isoflavones; Microvilli; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Sodium Chloride; Sodium-Hydrogen Exchangers; Transfection; Wortmannin | 1996 |
Genistein, a tyrosine kinase inhibitor, reduces EGF-induced EGF receptor internalization and degradation in human hepatoma HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Isoflavones; Kinetics; Liver Neoplasms; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 1996 |
Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav.
Topics: Antigen-Antibody Reactions; CD18 Antigens; Cell Adhesion; Cell Cycle Proteins; Enzyme Inhibitors; Genistein; Humans; Integrins; Isoflavones; Neutrophils; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Proto-Oncogene Proteins p21(ras); Receptors, Leukocyte-Adhesion; Signal Transduction | 1996 |
Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells.
Topics: Calcium; Calcium Channels; Depression, Chemical; Enzyme Inhibitors; Extracellular Space; Genistein; Humans; Intracellular Fluid; Ionomycin; Ionophores; Isoflavones; Leukemia-Lymphoma, Adult T-Cell; Muromonab-CD3; Neoplasm Proteins; Phenols; Phosphatidylserines; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1996 |
Activation of phospholipase D is tightly coupled to the phagocytosis of Mycobacterium tuberculosis or opsonized zymosan by human macrophages.
Topics: 2,3-Diphosphoglycerate; Adult; Benzoquinones; Diphosphoglyceric Acids; Enzyme Activation; Enzyme Inhibitors; Ethanol; Genistein; Humans; Isoflavones; Lactams, Macrocyclic; Macrophage Activation; Macrophages; Mycobacterium tuberculosis; Phagocytosis; Phosphatidic Acids; Phosphatidylethanolamines; Phospholipase D; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Tuberculosis; Zymosan | 1996 |
Tyrosine phosphorylation of pp125FAK and paxillin in aortic endothelial cells induced by mechanical strain.
Topics: Animals; Aorta; Cattle; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Isoflavones; Nitriles; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Stress, Mechanical; Tissue Distribution; Tyrosine; Tyrphostins | 1996 |
Inhibition of neuropeptide-stimulated tyrosine phosphorylation and tyrosine kinase activity stimulates apoptosis in small cell lung cancer cells.
Topics: Apoptosis; Bombesin; Carcinoma, Small Cell; Cell Adhesion Molecules; Cell Cycle; Cell Division; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Isoflavones; Kinetics; Lung Neoplasms; Necrosis; Neuropeptides; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Neuropeptide; Substance P; Time Factors; Tumor Cells, Cultured; Tyrphostins | 1996 |
Purinergic stimulation of rat cardiomyocytes induces tyrosine phosphorylation and membrane association of phospholipase C gamma: a major mechanism for InsP3 generation.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Genistein; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoenzymes; Isoflavones; Kinetics; Male; Myocardium; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Type C Phospholipases | 1996 |
Effects of mitogens on androgen receptor-mediated transactivation.
Topics: Animals; Cell Line; COS Cells; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; HeLa Cells; Insulin-Like Growth Factor I; Intracellular Membranes; Isoflavones; Ligands; Mitogens; Phosphorylation; Phosphotyrosine; Rats; Receptors, Androgen; Signal Transduction; Transcriptional Activation; Tyrosine; Vanadates | 1996 |
Intracellular signaling is changed after clustering of the neural cell adhesion molecules axonin-1 and NgCAM during neurite fasciculation.
Topics: Animals; Casein Kinase II; Cell Adhesion Molecules, Neuron-Glia; Cell Adhesion Molecules, Neuronal; Cell Communication; Cell Differentiation; Cells, Cultured; Chick Embryo; Contactin 2; Enzyme Inhibitors; Ganglia, Spinal; Genistein; Heparin; Isoflavones; Molecular Weight; Neurites; Oligonucleotides, Antisense; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Ribosomal Protein S6 Kinases; Signal Transduction | 1996 |
A role for phosphoinositide 3-kinase in bacterial invasion.
Topics: Androstadienes; Animals; Bacterial Proteins; Cell Line; Chromones; Cytochalasin D; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Isoflavones; Listeria monocytogenes; Membrane Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Tumor Cells, Cultured; Wortmannin | 1996 |
Activation of Src-family tyrosine kinases during Fas-induced apoptosis.
Topics: Animals; Apoptosis; Cells, Cultured; Enzyme Inhibitors; fas Receptor; Genistein; Humans; Isoflavones; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Monocytes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-fyn; Signal Transduction; src-Family Kinases; T-Lymphocytes; Ubiquitin-Protein Ligases | 1996 |
Tyrosine phosphorylation and [Ca2+]i elevation induced by hemolysate in bovine endothelial cells: implications for cerebral vasospasm.
Topics: Animals; Calcium; Cattle; Cells, Cultured; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Hemolysis; Ischemic Attack, Transient; Isoflavones; Nitriles; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pulmonary Artery; Signal Transduction; Subarachnoid Hemorrhage; Thapsigargin; Tyrphostins | 1996 |
Stimulation of inorganic phosphate transport by insulin-like growth factor I and vanadate in opossum kidney cells is mediated by distinct protein tyrosine phosphorylation processes.
Topics: Adaptor Proteins, Signal Transducing; Animals; Benzoquinones; Cell Line; Enzyme Inhibitors; Epithelium; Genistein; Humans; Insulin; Insulin-Like Growth Factor I; Isoflavones; Kidney; Lactams, Macrocyclic; Naphthalenes; Oncogene Proteins; Opossums; Phosphates; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Recombinant Proteins; Rifabutin; Signal Transduction; Sodium; Staurosporine; Vanadates | 1996 |
Aldosterone and insulin stimulate amiloride-sensitive sodium transport in A6 cells by additive mechanisms.
Topics: Aldosterone; Amiloride; Animals; Biological Transport, Active; Cell Line; Electric Conductivity; Enzyme Inhibitors; Genistein; Insulin; Isoflavones; Kidney; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Xenopus laevis | 1996 |
Leishmania-induced tyrosine phosphorylation in the host macrophage and its implication to infection.
Topics: Animals; Benzoquinones; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Genistein; Immunohistochemistry; Isoflavones; Lactams, Macrocyclic; Leishmaniasis; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Microscopy, Electron; Nitriles; Organophosphorus Compounds; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Staurosporine; Tyrphostins; Vanadates | 1996 |
Acrosome membrane associated protein kinase activity in hamster spermatozoa.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Animals; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Epididymis; Genistein; Heparin; Isoflavones; Male; Membrane Proteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Spermidine; Spermine | 1996 |
Tyrosine phosphorylation of the dense plaque protein paxillin is regulated during smooth muscle contraction.
Topics: Acetylcholine; Analysis of Variance; Animals; Blotting, Western; Cytoskeletal Proteins; Dogs; Genistein; In Vitro Techniques; Isoflavones; Isometric Contraction; Kinetics; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Serotonin; Trachea; Tyrosine | 1996 |
Regulation of protein tyrosine phosphorylation in human sperm by a calcium/calmodulin-dependent mechanism: identification of A kinase anchor proteins as major substrates for tyrosine phosphorylation.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcimycin; Calcium; Calmodulin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Humans; Isoflavones; Male; Mice; Phenanthridines; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Proteins; Seminal Plasma Proteins; Spermatozoa; Staurosporine | 1996 |
[Studies on protein tyrosine phosphorylation in mouse oocyte maturation].
Topics: Animals; Antibodies, Monoclonal; Female; Genistein; In Vitro Techniques; Isoflavones; Mice; Oocytes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases | 1996 |
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.
Topics: Amyloid beta-Protein Precursor; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Isoflavones; Kidney; Maleimides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Tyrosine | 1996 |
Multiple routes and regulation by tyrosine phosphorylation characterize the ATP-dependent transport of 2,4-dinitrophenyl S-glutathione in inside-out vesicles from human erythrocytes.
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Biological Transport, Active; Carrier Proteins; Cell-Free System; Enzyme Inhibitors; Erythrocyte Membrane; Genistein; Glucuronates; Glutathione; Humans; Isoflavones; Leukemia L1210; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Substrate Specificity | 1997 |
Ca2+ release and Ca2+ influx in Chinese hamster ovary cells expressing the cloned mouse B2 bradykinin receptor: tyrosine kinase inhibitor-sensitive and- insensitive processes.
Topics: Animals; Binding Sites; Bradykinin; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Genistein; Homeostasis; Inositol 1,4,5-Trisphosphate; Isoflavones; Manganese; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Bradykinin B2; Receptors, Bradykinin; Thapsigargin; Transfection | 1997 |
Protein tyrosine kinase activity regulates nitric oxide synthase induction in rat hepatocytes.
Topics: Animals; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Genistein; Interleukin-1; Isoflavones; Liver; Male; Nitric Oxide Synthase; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Subnuclear trafficking of glucocorticoid receptors in vitro: chromatin recycling and nuclear export.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cell Compartmentation; Cell Membrane Permeability; Cell Nucleus; Chromatin; Corticosterone; Digitonin; Enzyme Inhibitors; Genistein; Heparin; HSP90 Heat-Shock Proteins; Isoflavones; Liver; Liver Neoplasms, Experimental; Microcystins; Molybdenum; Peptides, Cyclic; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Glucocorticoid; Tumor Cells, Cultured; Tungsten Compounds; Vanadates | 1997 |
Protein tyrosine phosphorylation influences adhesive junction assembly and follicular organization of cultured thyroid epithelial cells.
Topics: Animals; Cell Adhesion; Cell Aggregation; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Epithelium; Genistein; Intercellular Junctions; Isoflavones; Morphogenesis; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Swine; Thyrotropin; Tight Junctions; Vinculin | 1997 |
Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit.
Topics: Animals; Calcium; Carbachol; Cell Line; CHO Cells; Cricetinae; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoflavones; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Cholinergic; Receptors, Metabotropic Glutamate; Signal Transduction | 1997 |
Tyrosine phosphorylation is required for ehrlichial internalization and replication in P388D1 cells.
Topics: Animals; Benzoquinones; Ehrlichia; Genistein; Glutamine; Isoflavones; Lactams, Macrocyclic; Leukemia P388; Macrophages; Methionine; Mice; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine | 1997 |
Heat stress induces tyrosine phosphorylation/activation of kinase FA/GSK-3 alpha (a human carcinoma dedifferentiation modulator) in A431 cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Genistein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Heat Stress Disorders; Humans; Isoflavones; Myelin Basic Protein; Phosphotyrosine; Protein-Tyrosine Kinases; Time Factors; Tumor Cells, Cultured | 1997 |
Rapid tyrosine phosphorylation of HS1 in the response of mouse lymphoma L5178Y-R cells to photodynamic treatment sensitized by the phthalocyanine Pc 4.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Blood Proteins; Cell Death; Enzyme Inhibitors; Genistein; Indoles; Isoflavones; Leukemia L5178; Light; Mice; Molecular Weight; Phosphorylation; Phosphotyrosine; Photochemotherapy; Photosensitizing Agents; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Vanadates | 1997 |
Hydrogen peroxide-induced phospholipase D activation in rat pheochromocytoma PC12 cells: possible involvement of Ca2+-dependent protein tyrosine kinase.
Topics: Animals; Benzoquinones; Blotting, Western; Calcimycin; Calcium; Cinnamates; Enzyme Activation; Enzyme Inhibitors; Genistein; Hydrogen Peroxide; Isoflavones; Lactams, Macrocyclic; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sulfides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Signaling mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of tyrosine phosphorylation.
Topics: Calcitriol; Calcium; Calcium Channel Blockers; Cell Adhesion; Cell Differentiation; Genistein; Humans; Isoflavones; Lipopolysaccharides; Macrophage-1 Antigen; Monocytes; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1997 |
Tyrosine phosphorylation in contraction of opossum esophageal longitudinal muscle in response to SNP.
Topics: Animals; Benzylidene Compounds; Carbachol; Cyclic GMP; Enzyme Inhibitors; Genistein; Isoflavones; Isometric Contraction; Models, Biological; Muscle Relaxation; Muscle, Smooth; Nitriles; Nitroprusside; Opossums; Phosphorylation; Phosphotyrosine; Potassium Chloride; Protein-Tyrosine Kinases; Trachea; Tyrosine; Tyrphostins | 1997 |
Endotoxin induces endothelial barrier dysfunction through protein tyrosine phosphorylation.
Topics: Animals; Benzoquinones; Biological Transport; Cattle; Cell Adhesion Molecules; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Endotoxins; Enzyme Inhibitors; Escherichia coli; Genistein; Isoflavones; Lactams, Macrocyclic; Lipopolysaccharides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pulmonary Artery; Quinones; Rifabutin; Serum Albumin, Bovine; Vanadates | 1997 |
Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway.
Topics: 3T3 Cells; Adipocytes; Androstadienes; Animals; Antibodies; Biological Transport; Cell Membrane; Deoxyglucose; Genistein; Glucose; Glucose Transporter Type 4; Insulin; Membrane Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Nerve Tissue Proteins; Osmolar Concentration; Phosphotyrosine; Protein-Tyrosine Kinases; Qa-SNARE Proteins; Sorbitol; Wortmannin; Xylose | 1997 |
Role of tyrosine kinases in extracellular matrix-mediated modulation of arterial smooth muscle cell phenotype.
Topics: Actins; Animals; Cell Adhesion Molecules; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Male; Muscle, Smooth, Vascular; Phenotype; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley | 1997 |
Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases.
Topics: Actins; Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin B; Endothelium, Vascular; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Genistein; GRB2 Adaptor Protein; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Receptors, Vitronectin; Rheology; Signal Transduction; Son of Sevenless Proteins | 1997 |
Gastrin induces IP3 formation through phospholipase C gamma 1 and pp60c-src kinase.
Topics: Animals; Antibodies; Cells, Cultured; Enzyme Inhibitors; Gastrins; Genistein; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; Isoenzymes; Male; Pertussis Toxin; Phospholipase C beta; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Precipitin Tests; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Sprague-Dawley; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella | 1998 |
Stimulation of G-protein coupled receptors in vascular smooth muscle cells induces tyrosine kinase dependent increases in calcium without tyrosine phosphorylation of phospholipase C gamma-1.
Topics: Angiotensin II; Animals; Calcium; Cell Line; Endothelins; Genistein; GTP-Binding Proteins; Isoenzymes; Muscle, Smooth, Vascular; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Rats; Receptors, Cell Surface; Serotonin; Type C Phospholipases; Vasopressins | 1998 |
Protein tyrosine phosphorylation mediates TNF-induced endothelial-neutrophil adhesion in vitro.
Topics: Benzylidene Compounds; Cell Adhesion; Cells, Cultured; E-Selectin; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Humans; Intercellular Adhesion Molecule-1; Kinetics; Neutrophils; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Tumor Necrosis Factor-alpha; Tyrphostins | 1998 |
The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway.
Topics: Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Squamous Cell; Enzyme Activation; Enzyme Induction; Genistein; Glycogen Synthase Kinase 3; Humans; Phosphorylation; Phosphotyrosine; Protein Kinase C; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1998 |
Cell growth inhibition by a novel vitamin K is associated with induction of protein tyrosine phosphorylation.
Topics: Carcinoma, Hepatocellular; Catechols; Cell Division; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Humans; Kinetics; Liver Neoplasms; Mercaptoethanol; Naphthoquinones; Nitriles; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sulfhydryl Compounds; Tumor Cells, Cultured; Tyrphostins; Vanadates; Vitamin K | 1998 |
Early and late events in Fc epsilon RI signal transduction in human cultured mast cells.
Topics: Adaptor Proteins, Signal Transducing; Blood Proteins; Calcium; Cells, Cultured; Cross-Linking Reagents; Enzyme Activation; Enzyme Precursors; Fetal Blood; Genistein; Histamine Release; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Isoenzymes; Mast Cells; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptors, IgE; Signal Transduction; src-Family Kinases; Subcellular Fractions; Syk Kinase; Type C Phospholipases; Ubiquitin-Protein Ligases | 1997 |
Induction of tyrosine phosphorylation in human MHC class II-positive antigen-presenting cells by stimulation with contact sensitizers.
Topics: Antigen-Presenting Cells; Cells, Cultured; Dendritic Cells; Dermatitis, Contact; Dinitrofluorobenzene; Enzyme Activation; Genistein; Haptens; Histocompatibility Antigens Class II; Humans; Interleukin-1; Lymphocytes; Monocytes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger | 1998 |
Growth inhibitory effect of bovine lactoferrin to Toxoplasma gondii tachyzoites in murine macrophages: tyrosine phosphorylation in murine macrophages induced by bovine lactoferrin.
Topics: Animals; Cattle; Cells, Cultured; Female; Genistein; Lactoferrin; Macrophages, Peritoneal; Mice; Phosphorylation; Phosphotyrosine; Toxoplasma | 1998 |
Cell differentiation and cell-cycle alterations by tyrosine kinase inhibitors in human melanoma cells.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cinnamates; Enzyme Inhibitors; Eye Neoplasms; Gene Expression Regulation, Neoplastic; Genistein; Humans; Melanoma; Naphthalenes; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Skin Neoplasms; Tumor Cells, Cultured | 1997 |
Modulation of baroreflex sensitivity by the state of protein tyrosine phosphorylation in the brainstem of the rat.
Topics: Animals; Atropine; Baroreflex; Brain Stem; Enzyme Inhibitors; Genistein; Hemodynamics; Male; Muscarinic Antagonists; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Vanadates | 1998 |
Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia.
Topics: Actins; Animals; Cadherins; Cell Line; Cell Membrane Permeability; Dogs; Genistein; Immunohistochemistry; Inulin; Kidney; Membrane Proteins; Nitriles; Peroxides; Phalloidine; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rhodamines; Staurosporine; Tight Junctions; Tyrphostins; Vanadates; Zonula Occludens-1 Protein | 1998 |
H2O2 and genistein differentially modulate protein tyrosine phosphorylation, endothelial morphology, and monolayer barrier function.
Topics: Actins; Animals; beta Catenin; Cattle; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Genistein; Hydrogen Peroxide; Kinetics; Phosphoproteins; Phosphorylation; Phosphotyrosine; Pulmonary Artery; Trans-Activators | 1998 |
Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo.
Topics: Animals; Axons; Benzoquinones; Cell Movement; Central Nervous System; Culture Techniques; Enzyme Inhibitors; Genistein; Grasshoppers; Growth Cones; Immunoblotting; Immunohistochemistry; Interneurons; Lactams, Macrocyclic; Microscopy, Electron; Motor Neurons; Muscles; Nerve Net; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction | 1998 |
Pathways for eosinophil lipid body induction: differing signal transduction in cells from normal and hypereosinophilic subjects.
Topics: Adult; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Benzoquinones; Enzyme Inhibitors; Eosinophilia; Eosinophils; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Inclusion Bodies; Interleukin-3; Interleukin-5; Lactams, Macrocyclic; Lipids; Phosphoproteins; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Quinones; Reference Values; Rifabutin; Signal Transduction | 1998 |
The counteradhesive protein SPARC regulates an endothelial paracellular pathway through protein tyrosine phosphorylation.
Topics: Albumins; Benzoquinones; beta Catenin; Biological Transport; Cells, Cultured; Cytoskeletal Proteins; Endothelium; Enzyme Inhibitors; Genistein; Immunoblotting; Intercellular Junctions; Lactams, Macrocyclic; Osteonectin; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Trans-Activators | 1998 |
Regulation of the renal Na-HCO3 cotransporter: IX. Modulation by insulin, epidermal growth factor and carbachol.
Topics: Aminobenzoates; Animals; Antibodies; Carrier Proteins; Cells, Cultured; Cinnamates; Enzyme Activation; Epidermal Growth Factor; Genistein; Insulin; Intercellular Signaling Peptides and Proteins; Kidney Tubules; Membrane Proteins; meta-Aminobenzoates; Peptides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Salicylates; Sodium-Bicarbonate Symporters | 1998 |
Different proliferative responses of Gi/o-protein-coupled receptors in human myometrial smooth muscle cells. A possible role of calcium.
Topics: Adrenergic Agents; Binding, Competitive; Calcium; Cell Division; Cell Size; Cells, Cultured; Colforsin; DNA; Female; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lysophospholipids; Myometrium; Norepinephrine; Phosphorylation; Phosphotyrosine; Pregnancy; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid | 1998 |
MAP-kinase dependent induction of monocytic procoagulant activity by beta2-integrins.
Topics: Blood Coagulation Factors; CD18 Antigens; Cell Line; Cross-Linking Reagents; Enzyme Inhibitors; Flavonoids; Genistein; Humans; In Vitro Techniques; Inflammation Mediators; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Monocytes; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases | 1998 |
Concanavalin A modulates tyrosine phosphorylation and activation of a type II phosphatidylinositol 4-kinase in rat splenic lymphocytes.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Antibodies; Concanavalin A; Enzyme Activation; Enzyme Inhibitors; Genistein; Lymphocyte Activation; Lymphocytes; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Rabbits; Rats; Rats, Wistar; Spleen; Tyrosine | 1998 |
A role for host phosphoinositide 3-kinase and cytoskeletal remodeling during Cryptosporidium parvum infection.
Topics: Animals; Azepines; Cattle; Cryptosporidium parvum; Cytochalasin D; Cytoskeleton; Diacetyl; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Light Signal Transduction; Microscopy, Immunoelectron; Naphthalenes; Phosphatidylinositol 3-Kinases; Phosphotyrosine; Protein-Tyrosine Kinases; Staurosporine; Suramin; Uncoupling Agents | 1999 |
Involvement of tyrosine phosphorylation in HMG-CoA reductase inhibitor-induced cell death in L6 myoblasts.
Topics: Animals; Apoptosis; Benzoquinones; Cell Line; Cell Size; DNA Fragmentation; Genistein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactams, Macrocyclic; Mevalonic Acid; Molecular Weight; Muscle, Skeletal; Phosphorylation; Phosphotyrosine; Pravastatin; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Signal Transduction; Simvastatin; Time Factors | 1999 |
Involvement of host cell tyrosine phosphorylation in the invasion of HEp-2 cells by Bartonella bacilliformis.
Topics: Antibodies, Monoclonal; Antigens, CD; Bartonella; Bartonella Infections; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Integrin alpha1; Integrin beta1; Larynx; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Sulfur Radioisotopes | 1999 |
Phosphotyrosine signalling as a regulator of neural crest cell adhesion and motility.
Topics: Animals; Benzoquinones; Cadherins; Cell Adhesion; Cell Culture Techniques; Cell Movement; Coturnix; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Genistein; Lactams, Macrocyclic; Neural Crest; Ouabain; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Sodium-Potassium-Exchanging ATPase; Vanadates | 1999 |
Induction of cell shape changes through activation of the interleukin-3 common beta chain receptor by the RON receptor-type tyrosine kinase.
Topics: Actins; Bone Marrow Cells; Cell Division; Cell Size; Enzyme Activation; Fluorescent Antibody Technique; Genistein; Growth Substances; Hepatocyte Growth Factor; Interleukin-3; Janus Kinase 2; Microscopy, Phase-Contrast; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Interleukin-3; Signal Transduction | 1999 |
Lysophosphatidylcholine stimulates phospholipase D activity in mouse peritoneal macrophages.
Topics: Acetylation; Animals; Azepines; Cell Line; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Genistein; Lysophosphatidylcholines; Lysophospholipids; Macrophages, Peritoneal; Mice; Phosphatidic Acids; Phospholipase D; Phosphotyrosine; Platelet Membrane Glycoproteins; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triazoles | 1999 |
Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.
Topics: Arsenicals; Cell Nucleus; Copper; Diamide; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; Hydrogen Peroxide; Iron; Lymphocytes; Oxidative Stress; Phenanthrolines; Phosphorylation; Phosphotyrosine; Phytohemagglutinins; Protein Tyrosine Phosphatases; Reactive Oxygen Species; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1999 |
The priming effect of 12(S)-hydroxyeicosatetraenoic acid on lymphocyte phospholipase D involves specific binding sites.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Binding Sites; Binding, Competitive; Concanavalin A; Enzyme Activation; Enzyme Inhibitors; Fatty Acids; Genistein; Humans; Leukocytes, Mononuclear; Lymphocytes; Naphthalenes; Pertussis Toxin; Phospholipase D; Phosphorylation; Phosphotyrosine; Protein Kinase C; Suramin; Tritium; Virulence Factors, Bordetella | 1999 |
Phosphotyrosine of macrophage by low-density lipoproteins from hemodialysis patients.
Topics: Enzyme Inhibitors; Genistein; Humans; Immunoblotting; Lipoproteins, LDL; Macrophages; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Renal Dialysis; Tyrosine | 1999 |
Increased tyrosine kinase activity but not calcium mobilization is required for ceramide-induced apoptosis.
Topics: Animals; Apoptosis; Calcimycin; Calcium; Cell Line; Ceramides; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Fibroblasts; Genistein; Insulin; Insulin-Like Growth Factor I; Lysophospholipids; Mice; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, IGF Type 1; Signal Transduction; Sphingosine; Thapsigargin; Vanadates | 1999 |
Cell volume-dependent regulation of L-selectin shedding in neutrophils. A role for p38 mitogen-activated protein kinase.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Size; Cytosol; Enzyme Inhibitors; Genistein; Humans; Hydrogen-Ion Concentration; Hydroxamic Acids; Hypertonic Solutions; Imidazoles; In Vitro Techniques; L-Selectin; Macrophage-1 Antigen; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphotyrosine; Protease Inhibitors; Pyridines | 1999 |
Activation of follicle cell surface phospholipase by tyrosine kinase dependent pathway is an essential event in Ascidian fertilization.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Enzyme Activation; Enzyme Inhibitors; Genistein; Glycoside Hydrolases; Membrane Glycoproteins; Oocytes; Phospholipases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Reproduction; Tyrphostins; Urochordata | 1999 |
Spatial organization of EGF receptor transmodulation by PDGF.
Topics: Cell Membrane; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Genistein; Humans; Immunosorbent Techniques; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Signal Transduction; Structure-Activity Relationship | 1999 |
Legionella pneumophila invasion of MRC-5 cells induces tyrosine protein phosphorylation.
Topics: Cell Line; Enzyme Inhibitors; Fibroblasts; Genistein; Humans; Intracellular Fluid; Kinetics; Legionella pneumophila; Lung; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases | 1999 |
Laminin stimulates protein tyrosine dephosphorylation in PC12 cells.
Topics: Animals; Aurintricarboxylic Acid; Enzyme Inhibitors; Genistein; Kinetics; Laminin; PC12 Cells; Phenols; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quercetin; Rats; Signal Transduction; Vanadates | 1999 |
Insulin-induced stimulation of Na+,K(+)-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the alpha-subunit at Tyr-10.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Enzyme Activation; Genistein; Insulin; Insulin Antagonists; Kidney Tubules, Proximal; Male; Opossums; Ouabain; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Transfection; Tyrosine; Vanadates | 1999 |
Early effects of protein kinase modulators on DNA synthesis in rat cerebral cortex.
Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Camptothecin; Cerebral Cortex; Dimethyl Sulfoxide; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Genistein; Lactams, Macrocyclic; Naphthalenes; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Staurosporine; Steroids; Vanadates | 1999 |
Low extracellular Mg2+ contraction of arterial muscle: role of protein kinase C and protein tyrosine phosphorylation.
Topics: Animals; Aorta, Thoracic; Arteries; Calcium; Carbazoles; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Genistein; In Vitro Techniques; Indoles; Magnesium; Male; Maleimides; Muscle Contraction; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar | 1999 |
An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; ErbB Receptors; Genistein; GTP-Binding Proteins; Humans; Lysophospholipids; Mutation; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Transcriptional Activation | 1999 |
Phosphorylation-dependent regulation of skeletogenesis in sea urchin micromere-derived cells and embryos.
Topics: Animals; Bone and Bones; Cell Differentiation; Cells, Cultured; Collagen; Embryo, Nonmammalian; Enzyme Inhibitors; Genistein; Morphogenesis; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA, Messenger; Sea Urchins; Vanadates | 1999 |
A role for bovine herpesvirus 1 (BHV-1) glycoprotein E (gE) tyrosine phosphorylation in replication of BHV-1 wild-type virus but not BHV-1 gE deletion mutant virus.
Topics: Animals; Capsid; Cell Line; Dogs; Gene Deletion; Genistein; Herpesvirus 1, Bovine; Mutation; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Quinazolines; Tyrphostins; Viral Envelope Proteins; Viral Proteins; Virus Replication | 2000 |
Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion.
Topics: Amino Acid Motifs; Antigens, Bacterial; Bacterial Proteins; Biological Transport; Enzyme Inhibitors; Epithelial Cells; Fluorescent Antibody Technique; Gastric Mucosa; Genes, Bacterial; Genetic Complementation Test; Genistein; Helicobacter pylori; Humans; Mutation; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Staurosporine; Tumor Cells, Cultured; Virulence | 2000 |
The fibronectin-derived anti-adhesive peptide III14-2 suppresses adhesion and apoptosis of leukemic cell lines through down-regulation of protein-tyrosine phosphorylation.
Topics: Apoptosis; Arsenicals; Cell Adhesion; DNA Fragmentation; Down-Regulation; Fibronectins; Genistein; HL-60 Cells; Humans; K562 Cells; Microscopy, Fluorescence; Peptide Fragments; Phosphorylation; Phosphotyrosine; Receptors, Fibronectin | 2000 |
Tyrosine phosphorylation of a 34-kDa protein induced by cross-linking a novel glycosylphosphatidylinositol-anchored glycoprotein (GPI-80) on human neutrophils that may regulate their adherence and migration.
Topics: Amidohydrolases; Androstadienes; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Chelating Agents; Cross-Linking Reagents; Cytochalasin B; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Genistein; GPI-Linked Proteins; Humans; Hydrolases; Indoles; Mice; Mice, Inbred BALB C; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Signal Transduction; Time Factors; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Activation of Akt during simulated ischemia/reperfusion in cardiac myocytes.
Topics: Androstadienes; Animals; Animals, Newborn; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Genistein; Imidazoles; Kinetics; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Pyridines; Rats; Retroviridae Proteins, Oncogenic; Wortmannin | 2000 |
HIV-1 Tat increases endothelial solute permeability through tyrosine kinase and mitogen-activated protein kinase-dependent pathways.
Topics: Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Gene Products, tat; Genistein; HIV; Humans; Immunohistochemistry; Permeability; Phosphotyrosine; Protein Tyrosine Phosphatases; Recombinant Proteins; Signal Transduction; tat Gene Products, Human Immunodeficiency Virus; Time Factors | 2000 |
Biphasic effect of UVA radiation on STAT1 activity and tyrosine phosphorylation in cultured human keratinocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; DNA; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Keratinocytes; Lipid Peroxidation; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Reactive Oxygen Species; STAT1 Transcription Factor; Thiobarbituric Acid Reactive Substances; Trans-Activators; Transcription, Genetic; Ultraviolet Rays | 2000 |
Tyrosine phosphorylation: a critical component in the formation of hemidesmosomes.
Topics: Alkalies; Animals; Antigens, CD; Autoantigens; Basement Membrane; Carrier Proteins; Collagen; Collagen Type XVII; Cytoskeletal Proteins; Dystonin; Epithelium, Corneal; Genistein; Hemidesmosomes; Immunohistochemistry; Integrin beta4; Microscopy, Electron; Nerve Tissue Proteins; Non-Fibrillar Collagens; Organ Culture Techniques; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits | 2000 |
PLC-gamma1 signaling pathway and villin activation are involved in actin cytoskeleton reorganization induced by Na+/Pi cotransport up-regulation.
Topics: Actin Cytoskeleton; Actins; Animals; Biological Transport; Carrier Proteins; Cell Line; Cytoskeleton; Enzyme Activation; Genistein; Isoenzymes; Microfilament Proteins; Microscopy, Confocal; Opossums; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein Binding; Signal Transduction; Sodium; Sodium-Phosphate Cotransporter Proteins; Solubility; Symporters; Type C Phospholipases; Up-Regulation | 2000 |
Involvement of tyrosine kinase activity in 1alpha,25(OH)2-vitamin D3 signal transduction in skeletal muscle cells.
Topics: Animals; Benzoquinones; Calcitriol; Calcium; Calcium Signaling; Cells, Cultured; Chick Embryo; DNA; Enzyme Activation; Flavonoids; Genistein; Isoenzymes; Lactams, Macrocyclic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-myc; Quinones; Rifabutin; Signal Transduction; Type C Phospholipases; Vanadates | 2000 |
The upregulating effect of insulin and vanadate on cell surface insulin receptors in rat adipocytes is modulated by glucose and energy availability.
Topics: Adipocytes; Animals; Biological Transport; Cell Membrane; Cytochalasin B; Energy Metabolism; Enzyme Inhibitors; Genistein; Glucose; Glycosylation; Humans; Insulin; Kinetics; Male; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Tunicamycin; Vanadates | 2000 |
Interleukin-6-induced tyrosine phosphorylation of phospholipase C-gamma1 in PC12 cells.
Topics: Animals; Genistein; Inositol Phosphates; Interleukin-6; Isoenzymes; Neurites; Neurons; PC12 Cells; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Signal Transduction; Type C Phospholipases | 2000 |
Tyrosine phosphorylation of the kappa -opioid receptor regulates agonist efficacy.
Topics: Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cells, Cultured; Female; Genistein; Insulin; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Phosphotyrosine; Protein Structure, Secondary; Pyrrolidines; Rats; Receptors, Opioid, kappa; Recombinant Proteins; Xenopus laevis | 2000 |
Role of receptor protein tyrosine phosphatase alpha (RPTPalpha) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels.
Topics: Animals; Enzyme Inhibitors; Female; Gene Expression; Genistein; Humans; Kinetics; Kv1.1 Potassium Channel; Kv1.2 Potassium Channel; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Phosphotyrosine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Receptors, Serotonin; Serotonin; Transfection; Vanadates; Xenopus laevis | 2000 |
c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Aorta; Benzoquinones; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Genistein; GRB2 Adaptor Protein; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Pyrimidines; Quinazolines; Quinones; Rifabutin; Swine; Transcriptional Activation; Tyrphostins | 2001 |
Mac-1-dependent tyrosine phosphorylation during neutrophil adhesion.
Topics: Antibodies, Monoclonal; Cell Adhesion; Cytochalasin B; Enzyme Inhibitors; Fibrinogen; Genistein; Glutathione Transferase; Humans; In Vitro Techniques; Interleukin-8; Kinetics; Macrophage-1 Antigen; Neutrophil Activation; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; src Homology Domains; Staurosporine; Tetradecanoylphorbol Acetate; Vanadates | 2001 |
Pertussis toxin activates tyrosine kinase signaling cascade in myelomonocytic cells: a mechanism for cell adhesion.
Topics: Cell Adhesion; Chromones; Dimethyl Sulfoxide; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Kinetics; Lipopolysaccharide Receptors; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Morpholines; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Transforming Growth Factor beta; Tyrphostins; U937 Cells; Virulence Factors, Bordetella | 2001 |
Engagement of endogenous ganglioside GM1a induces tyrosine phosphorylation involved in neuron-like differentiation of PC12 cells.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Size; Cholera Toxin; Chromatography, Thin Layer; Enzyme Activation; Flavonoids; G(M1) Ganglioside; Genistein; MAP Kinase Signaling System; Membrane Glycoproteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Molecular Weight; Neurites; Neurons; PC12 Cells; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Serine-Threonine Kinases; Rats; Receptor, trkA | 2001 |
Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction.
Topics: Anemia, Sickle Cell; Antigens, CD; Carrier Proteins; CD47 Antigen; Cell Adhesion; Cells, Cultured; Enzyme Inhibitors; Erythrocytes, Abnormal; Genistein; Humans; Models, Biological; Oligopeptides; Phosphotyrosine; Signal Transduction; Stilbenes; Stress, Physiological; Thrombospondins; Virulence Factors, Bordetella | 2001 |
Normalization of retinal vascular permeability in experimental diabetes with genistein.
Topics: Administration, Oral; Albumins; Animals; Blood-Retinal Barrier; Blotting, Western; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Male; Phosphotyrosine; Proliferating Cell Nuclear Antigen; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Retinal Vessels; Sucrose | 2001 |
Tyrosine phosphorylation of the catalytic subunit p110 of phosphatidylinositol-3 kinase induced by HMG-CoA reductase inhibitor inhibits its kinase activity in L6 myoblasts.
Topics: Animals; Benzoquinones; Catalytic Domain; Cell Line; Enzyme Inhibitors; Genistein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactams, Macrocyclic; Muscles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Simvastatin | 2001 |
Activation of JAK2 by the oxidative stress generated with oxidized low-density lipoprotein.
Topics: Cell Line; Cell Nucleus; Copper; DNA; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Genistein; Humans; Janus Kinase 2; Lipoproteins, LDL; Oxidative Stress; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Tyrphostins | 2001 |
Soluble fibrinogen modulates neutrophil functionality through the activation of an extracellular signal-regulated kinase-dependent pathway.
Topics: Apoptosis; Benzoquinones; Cell Degranulation; Cytoplasmic Granules; Enzyme Activation; Enzyme Inhibitors; Fibrinogen; Flavonoids; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Imidazoles; Kinetics; Lactams, Macrocyclic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neutrophils; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Pyridines; Quinones; Rifabutin; Solubility | 2002 |
pp60(c-src) is a negative regulator of laminin-1-mediated neurite outgrowth in chick sensory neurons.
Topics: Animals; Cell Differentiation; Cells, Cultured; Chick Embryo; Down-Regulation; Enzyme Inhibitors; Ganglia, Spinal; Genistein; Growth Cones; Laminin; Lasers; Neurites; Neurons, Afferent; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Pseudopodia | 2002 |
Flagellar adhesion between mating type plus and mating type minus gametes activates a flagellar protein-tyrosine kinase during fertilization in Chlamydomonas.
Topics: Animals; Bucladesine; Cell Adhesion; Chlamydomonas reinhardtii; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Flagella; Genistein; Hydrogen-Ion Concentration; Immunoblotting; Isoquinolines; Models, Biological; Peptides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Temperature; Time Factors | 2003 |
Tyrosine kinase mediated phosphorylation of the hexamerin receptor in the rice moth Corcyra cephalonica by ecdysteroids.
Topics: Animals; Autoradiography; Carrier Proteins; Cycloheximide; Dactinomycin; Ecdysterone; Enzyme Inhibitors; Fat Body; Genistein; Insect Proteins; Larva; Moths; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Cell Surface | 2003 |
Sensitivity of rabbit aorta and mesenteric artery to norepinephrine: role of tyrosine kinases.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Genistein; In Vitro Techniques; Isometric Contraction; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Myosin Light Chains; Norepinephrine; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Receptors, Adrenergic; Time Factors; Vasoconstrictor Agents | 2003 |
Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cell Degranulation; Cyclooxygenase 1; Cyclooxygenase 2; Cytochalasin B; Dinoprostone; Edema; Female; Gastric Mucosa; Gene Expression; Genistein; Hindlimb; Humans; Indomethacin; Isoenzymes; Korea; Leukotriene B4; Lipopolysaccharides; Macrophages, Peritoneal; Medicine, East Asian Traditional; Membrane Proteins; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Elastase; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plant Extracts; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Staurosporine; Stomach; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Epstein-Barr virus (EBV) latent membrane protein 2A regulates B-cell receptor-induced apoptosis and EBV reactivation through tyrosine phosphorylation.
Topics: Antigens, Viral; Apoptosis; Cell Line, Tumor; DNA Fragmentation; DNA, Viral; Genistein; Herpesvirus 4, Human; Humans; Phosphotyrosine; Receptors, Antigen, B-Cell; Viral Matrix Proteins; Virus Activation | 2005 |
Genistein-induced neuronal differentiation is associated with activation of extracellular signal-regulated kinases and upregulation of p21 and N-cadherin.
Topics: Butadienes; Cadherins; Cell Differentiation; Cell Line; Cell Line, Tumor; Central Nervous System; Cyclin-Dependent Kinase 5; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Genistein; Humans; Immunoblotting; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Nitriles; Phosphotyrosine; Proto-Oncogene Proteins p21(ras); Threonine; Time Factors; Tretinoin; Up-Regulation | 2005 |
Actin cytoskeleton remodelling in the anterior pituitary folliculostellate cell line TtT/GF: participation of the actin-binding protein cortactin.
Topics: Actins; Animals; Cell Line; Cortactin; Cytoskeleton; Genistein; Mice; Phosphotyrosine; Pituitary Gland, Anterior; Protein Binding; Protein Transport; Protein-Tyrosine Kinases | 2005 |
Avian reovirus activates a novel proapoptotic signal by linking Src to p53.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Capsid Proteins; Chlorocebus aethiops; Gene Expression Regulation; Genes, Viral; Genistein; Indoles; Models, Biological; Mutant Proteins; Orthoreovirus, Avian; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Reoviridae Infections; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Tumor Suppressor Protein p53; Ultraviolet Rays; Vero Cells; Virus Inactivation; Virus Replication | 2006 |
Regulation of airway goblet cell mucin secretion by tyrosine phosphorylation signaling pathways.
Topics: Adenosine Triphosphate; Cells, Cultured; Epithelial Cells; Estrenes; Genistein; Goblet Cells; Humans; Mucins; Phosphorylation; Phosphotyrosine; Protein Kinase C-delta; Protein Kinase Inhibitors; Pyrrolidinones; Respiratory System; Signal Transduction; Time Factors; Type C Phospholipases; Vanadates | 2007 |
Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Cycle; Cell Differentiation; Cell Line; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Genistein; Humans; Leukemia, Promyelocytic, Acute; Membrane Potential, Mitochondrial; Neoplasm Proteins; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Peptide Hydrolases; Phosphoserine; Phosphotyrosine; Promyelocytic Leukemia Protein; Protein Binding; Protein Folding; Protein Structure, Tertiary; Receptors, Retinoic Acid; Repressor Proteins; Transcription Factors; Tretinoin; Tumor Suppressor Proteins | 2007 |
Role of tyrosine phosphorylation in U46619-induced vasoconstriction of pulmonary vasculature and its modulation by genistein, daidzein, and equol.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blotting, Western; Caffeine; Calcimycin; Cattle; Dose-Response Relationship, Drug; Equol; Genistein; In Vitro Techniques; Isoflavones; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Phytoestrogens; Potassium Chloride; Protein-Tyrosine Kinases; Proteins; Pulmonary Artery; Pulmonary Veins; Tyrosine; Vasoconstriction | 2007 |
Both EGFR kinase and Src-related tyrosine kinases regulate human ether-à-go-go-related gene potassium channels.
Topics: Cell Line; ErbB Receptors; Ether-A-Go-Go Potassium Channels; Genistein; Humans; Ion Channel Gating; Phosphotyrosine; Point Mutation; Pyrimidines; src-Family Kinases; Tyrphostins; Vanadates | 2008 |
The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.
Topics: 4-Butyrolactone; beta Catenin; Caco-2 Cells; Cadherins; Cytoplasm; Epithelial Cells; Genistein; Homoserine; Humans; Intercellular Junctions; Membrane Proteins; Occludin; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Pseudomonas aeruginosa; Quorum Sensing; Staurosporine; Zonula Occludens-1 Protein | 2009 |
Group B Streptococcus induces tyrosine phosphorylation of annexin V and glutathione S-transferase in human umbilical vein endothelial cells.
Topics: Actins; Amino Acid Sequence; Annexin A5; Cell Adhesion; Cell Survival; Cytochalasin D; Cytoskeleton; Endothelial Cells; Genistein; Glutathione Transferase; Humans; Intracellular Space; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Peptides; Phosphotyrosine; Sequence Analysis, Protein; Streptococcus agalactiae; Umbilical Veins | 2009 |
Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways.
Topics: Amino Acid Sequence; Cell Line, Tumor; Down-Regulation; G2 Phase; Genistein; Humans; Isotope Labeling; Mass Spectrometry; Mitosis; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proteomics; Reproducibility of Results; Signal Transduction | 2010 |
In vitro activation and inhibition of recombinant EGFR tyrosine kinase expressed in Escherichia coli.
Topics: Adenosine Triphosphate; Cross-Linking Reagents; Dimerization; ErbB Receptors; Escherichia coli; Gene Expression Regulation, Enzymologic; Genes, erbB-1; Genistein; Glutaral; Glutathione Transferase; Humans; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sarcosine; Sequence Deletion; Solvents | 2013 |
Histone H2B monoubiquitination is involved in regulating the dynamics of microtubules during the defense response to Verticillium dahliae toxins in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Arsenicals; Gene Expression Regulation, Plant; Genistein; Histones; Microtubules; Mycotoxins; Phosphorylation; Phosphotyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Verticillium | 2014 |
Tyrphostin AG556 increases the activity of large conductance Ca
Topics: Animals; Basilar Artery; Cell Separation; Epidermal Growth Factor; ErbB Receptors; Genistein; HEK293 Cells; Humans; Indoles; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Male; Myocytes, Smooth Muscle; Phosphorylation; Phosphotyrosine; Protein Subunits; Rats, Sprague-Dawley; Tyrphostins; Vanadates; Vasodilation | 2017 |