phosphotyrosine has been researched along with cysteine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (45.45) | 18.2507 |
| 2000's | 12 (36.36) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbacid, M; Jing, S; Tapley, P | 1 |
| Lukas, TJ; Staros, JV; Woltjer, RL | 1 |
| Lee, ES; Lin, R; Steiner, M | 1 |
| Abboud, HE; Biswas, P; Choudhury, GG; Grandaliano, G | 1 |
| Ford, CE; Furlong, MT; Geahlen, RL; Harrison, ML | 1 |
| Wang, YD; Wong, K; Wood, WI | 1 |
| Stauffacher, CV; Van Etten, RL; Zhang, M | 1 |
| Barghini, I; Camici, G; Cappugi, G; Caselli, A; Chiarugi, P; Cirri, P; Manao, G; Pazzagli, L; Ramponi, G; Raugei, G | 1 |
| Decker, SJ; Dobrusin, EM; MacLean, D; McNamara, DJ; Milarski, KL; Pearl, CG; Sawyer, T; Thieme-Sefler, A; Zhang, ZY; Zhu, G | 1 |
| Barford, D; Burke, TR; Chen, L; Jia, Z; Wang, S; Yan, X; Ye, B; Zhang, ZY | 1 |
| Aitken, A; Learmonth, M | 1 |
| Kwon, KS; Rhee, SG; Wu, Y | 1 |
| Alligood, KJ; Charifson, PS; Consler, TG; Crosby, R; Feldman, PL; Gampe, RT; Gilmer, TM; Jordan, SR; Milstead, MW; Mohr, C; Peel, MR; Rocque, W; Rodriguez, M; Rusnak, DW; Shewchuk, LM; Sternbach, DD | 1 |
| Attié, T; Billaud, M; Chappuis-Flament, S; De Vita, G; Fusco, A; Lenoir, GM; Pasini, A; Santoro, M; Ségouffin-Cariou, C | 1 |
| Bradshaw, JM; Mitaxov, V; Waksman, G | 1 |
| Rosado, JA; Sage, SO | 1 |
| Berg, LJ; Ching, KA; Tsoukas, CD; Yang, WC | 1 |
| Elder, ME; Kadlecek, TA; Skoda-Smith, S; Wang, F; Weiss, A; Wu, J | 1 |
| Furukawa, T; Ichijo, T; Kawakami, N; Saito, H; Tsujikawa, K; Uchino, Y; Yamamoto, H | 1 |
| Cunnick, JM; Doupnik, CA; Mei, L; Wu, J | 1 |
| Amin, AR; Hamaguchi, M; Huang, P; Mon, NN; Oo, ML; Senga, T; Thant, AA | 1 |
| Erlanson, DA; Hansen, SK; He, MM; Kung, J; McDowell, RS; Randal, M; Simmons, RL; Waight, A | 1 |
| Ron, D; Rubin, C; Vaisman, N; Yarden, Y; Zwang, Y | 1 |
| Finch, P; Soloviev, M | 1 |
| Briggs, DC; Collister, M; Dickinson, RJ; Didmon, MJ; Fox, GC; Hanrahan, S; Keyse, SM; Knowles, PP; Makrantoni, V; McDonald, NQ; Shafiq, M; Stark, MJ; Totty, N | 1 |
| Abdulhussein, R; Koo, DH; Vogel, WF | 1 |
| Angelo, LS; Kohanim, S; Kurzrock, R; Wu, JY; Yang, DJ | 1 |
| Ahmad, R; Alam, M; Kosugi, M; Kufe, D; Uchida, Y | 1 |
| Chien, PN; Hwang, HS; Jeon, TJ; Jeong, DG; Kim, DS; Kim, JK; Kim, SJ; Ku, B; Park, H; Park, SY; Ryu, SE; Ryu, SY; Wei, CH | 1 |
| Anderson, GM; Baguley, TD; Brouillette, J; Chatterjee, M; Cuny, GD; Ellman, JA; Foscue, E; Ghosh, D; Glicksman, MA; Greengard, P; Gresack, J; Kanyo, J; Kurup, P; Lam, TT; Lombroso, PJ; Nairn, AC; Ononenyi, C; Seyb, K; Tautz, L; Xu, J; Zhang, Y | 1 |
| Arkin, MR; Aum, DJ; Barros, T; Horton, TM; Kuriyan, J; Shah, NH; Tao, A; Visperas, PR; Weiss, A; Wilson, CG; Winger, JA; Yan, Q | 1 |
| Jang, D; Jeong, K; Kwon, H; Lee, J; Pak, Y | 1 |
| Asai, A; Inoue, Y; Iwamoto, K; Matsuno, K; Muraoka, D; Ogo, N; Taguchi, K; Uehara, Y | 1 |
1 review(s) available for phosphotyrosine and cysteine
| Article | Year |
|---|---|
Peptidomics, current status.
Topics: Arginine; Chromatography, Affinity; Combinatorial Chemistry Techniques; Cysteine; Histidine; Humans; Lysine; Methionine; Peptides; Phosphotyrosine; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2005 |
32 other study(ies) available for phosphotyrosine and cysteine
| Article | Year |
|---|---|
Nerve growth factor mediates signal transduction through trk homodimer receptors.
Topics: 3T3 Cells; Animals; Cell Line; Cysteine; Humans; Kinetics; Macromolecular Substances; Methionine; Mice; Nerve Growth Factors; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Proteins; Signal Transduction; Transfection; Tyrosine; Vanadates | 1992 |
Direct identification of residues of the epidermal growth factor receptor in close proximity to the amino terminus of bound epidermal growth factor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chromatography, Affinity; Cross-Linking Reagents; Cysteine; Epidermal Growth Factor; ErbB Receptors; Humans; Iodine Radioisotopes; Mice; Molecular Sequence Data; Phosphotyrosine; Protein Conformation; Tyrosine | 1992 |
Thioallyl compounds: potent inhibitors of cell proliferation.
Topics: Animals; Antineoplastic Agents; Aorta, Thoracic; CDC2 Protein Kinase; Cell Division; Cells, Cultured; Cysteine; Endothelium, Vascular; Garlic; GTPase-Activating Proteins; Humans; Kinetics; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plants, Medicinal; Protein Tyrosine Phosphatases; Proteins; Rats; Tyrosine; Umbilical Veins | 1994 |
Mitogenic signaling of thrombin in mesangial cells: role of tyrosine phosphorylation.
Topics: Benzoquinones; Calcium; Cells, Cultured; Cysteine; DNA; Gene Expression; Genistein; Glomerular Mesangium; Humans; Immunoblotting; Inositol Phosphates; Isoflavones; Lactams, Macrocyclic; Mitogens; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Sulfur Radioisotopes; Thrombin; Tyrosine | 1994 |
Signaling-induced association of a tyrosine-phosphorylated 36-kDa protein with p50csk.
Topics: Animals; Antibodies; Blood Platelets; Cell Line; CSK Tyrosine-Protein Kinase; Cysteine; Glutathione Transferase; Humans; Immunoblotting; Kinetics; Leukemia, Erythroblastic, Acute; Methionine; Molecular Weight; Neoplasm Proteins; Oncogene Proteins, Viral; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; Receptors, IgG; src-Family Kinases; Sulfur Radioisotopes; Tumor Cells, Cultured; Tyrosine | 1994 |
Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or Jak-STAT activation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cell Line; Cysteine; Humans; Interleukin-3; Janus Kinase 2; Mice; Molecular Sequence Data; Mutagenesis; Oligodeoxyribonucleotides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Somatotropin; Recombinant Proteins; Signal Transduction; Trans-Activators; Transcription Factors; Transfection; Tyrosine | 1995 |
Crystal structure of bovine heart phosphotyrosyl phosphatase at 2.2-A resolution.
Topics: Acid Phosphatase; Amino Acid Sequence; Animals; Arginine; Binding Sites; Cattle; Computer Graphics; Crystallography, X-Ray; Cysteine; Erythrocytes; Humans; Isoenzymes; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Phosphotyrosine; Protein Folding; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Recombinant Proteins; Sequence Homology, Amino Acid; Tyrosine | 1994 |
The role of Cys-17 in the pyridoxal 5'-phosphate inhibition of the bovine liver low M(r) phosphotyrosine protein phosphatase.
Topics: Animals; Binding, Competitive; Cattle; Cloning, Molecular; Cysteine; Escherichia coli; Kinetics; Liver; Mutagenesis, Site-Directed; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Schiff Bases; Spectrophotometry, Ultraviolet; Tyrosine | 1993 |
Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Binding Sites; Cysteine; ErbB Receptors; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphopeptides; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Type C Phospholipases; Tyrosine | 1993 |
Small molecule interactions with protein-tyrosine phosphatase PTP1B and their use in inhibitor design.
Topics: Binding Sites; Calorimetry; Computer Simulation; Crystallography, X-Ray; Cysteine; Drug Design; Enzyme Inhibitors; Kinetics; Models, Molecular; Naphthalenes; Organophosphonates; Phosphotyrosine; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Recombinant Proteins; Serine | 1996 |
Analysis of sites of protein phosphorylation.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Sequence Analysis | 1997 |
Probing cellular protein targets of H2O2 with fluorescein-conjugated iodoacetamide and antibodies to fluorescein.
Topics: Antibodies; Blotting, Western; Catecholamines; Cysteine; Epidermal Growth Factor; Fluoresceins; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Imidazolines; Molecular Weight; Oxidants; Oxidation-Reduction; Papain; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Proteins; Substrate Specificity; Tumor Cells, Cultured | 1998 |
The formation of a covalent complex between a dipeptide ligand and the src SH2 domain.
Topics: Aldehydes; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cysteine; Dipeptides; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphotyrosine; Protein Conformation; Proteins; src Homology Domains | 1998 |
Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Cell Transformation, Neoplastic; Cysteine; Dimerization; Disulfides; Drosophila Proteins; Glycosylation; Hirschsprung Disease; Humans; Membrane Proteins; Mice; Models, Biological; Multiple Endocrine Neoplasia Type 2a; PC12 Cells; Phosphotyrosine; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Receptor Protein-Tyrosine Kinases; Transcriptional Activation | 1998 |
Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase.
Topics: Amino Acid Substitution; Arginine; Binding, Competitive; Calorimetry; Conserved Sequence; Cysteine; Evolution, Molecular; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphotyrosine; src Homology Domains; src-Family Kinases; Structure-Activity Relationship; Thermodynamics; Titrimetry | 1999 |
Farnesylcysteine analogues inhibit store-regulated Ca2+ entry in human platelets: evidence for involvement of small GTP-binding proteins and actin cytoskeleton.
Topics: Actins; Blood Platelets; Calcium; Cysteine; Cytochalasin D; Cytoskeleton; Diterpenes; Farnesol; Humans; In Vitro Techniques; Kinetics; Monomeric GTP-Binding Proteins; Phosphotyrosine; Protein Methyltransferases; Protein Prenylation; Thapsigargin; Thrombin | 2000 |
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.
Topics: Amino Acid Substitution; Androstadienes; Animals; Arginine; Blood Proteins; Cysteine; Enzyme Inhibitors; Glutamic Acid; Humans; Interleukin-2; Jurkat Cells; Lysine; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Sequence Homology, Amino Acid; Signal Transduction; T-Lymphocytes; Transfection; Wortmannin | 2001 |
Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70.
Topics: Amino Acid Motifs; Animals; Arginine; Catalysis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Differentiation; Cell Survival; Cells, Cultured; Cysteine; Enzyme Activation; Enzyme Precursors; Humans; Infant; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Male; Mice; Mutation, Missense; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Severe Combined Immunodeficiency; Syk Kinase; T-Lymphocyte Subsets; Up-Regulation; ZAP-70 Protein-Tyrosine Kinase | 2001 |
Distinct functions of the two protein tyrosine phosphatase domains of LAR (leukocyte common antigen-related) on tyrosine dephosphorylation of insulin receptor.
Topics: Animals; Binding Sites; COS Cells; Cysteine; Gene Deletion; Immunoblotting; Immunosorbent Techniques; Insulin; Mutagenesis; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor, Insulin; Receptors, Cell Surface; Serine; Structure-Activity Relationship; Substrate Specificity; Transfection | 2001 |
Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2.
Topics: Amino Acid Motifs; Animals; Binding Sites; COS Cells; Cysteine; Enzyme Activation; Epidermal Growth Factor; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mutation; Peptides; Phosphoproteins; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins | 2001 |
Cysteine residues in the C-terminal lobe of Src: their role in the suppression of the Src kinase.
Topics: Alkylating Agents; Allosteric Regulation; Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Catalysis; Catalytic Domain; Chlorocebus aethiops; Codon; COS Cells; CSK Tyrosine-Protein Kinase; Cysteine; Drug Resistance; Enzyme Inhibitors; Maleimides; Molecular Sequence Data; Oncogene Protein pp60(v-src); Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; src Homology Domains; src-Family Kinases; Structure-Activity Relationship | 2003 |
Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering.
Topics: Binding Sites; Biomimetic Materials; Crystallography, X-Ray; Cysteine; Models, Molecular; Oxalic Acid; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases | 2003 |
Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cysteine; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; Nerve Tissue Proteins; Phosphorylation; Phosphotyrosine; Protein Binding; Rats; Recombinant Proteins; RNA Interference; Signal Transduction; Transfection | 2005 |
Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Disulfides; Dual-Specificity Phosphatases; Fungi; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Oxidative Stress; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae Proteins; Substrate Specificity | 2007 |
Identification of disulfide-linked dimers of the receptor tyrosine kinase DDR1.
Topics: Cell Line; Collagen; Cysteine; Dimerization; Discoidin Domain Receptors; Disulfides; Enzyme Activation; Humans; Mutant Proteins; Phosphotyrosine; Protein Isoforms; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Structure-Activity Relationship | 2008 |
Molecular imaging of Bcr-Abl phosphokinase in a xenograft model.
Topics: Animals; Antibodies; Benzamides; Cysteine; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Indium Radioisotopes; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Nude; Phosphotyrosine; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Radioimmunodetection; Tumor Burden; Xenograft Model Antitumor Assays | 2009 |
MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.
Topics: Aerobiosis; Amino Acid Sequence; Animals; Cell Line, Tumor; Cysteine; Down-Regulation; ErbB Receptors; Gene Silencing; Glycolysis; Humans; Molecular Sequence Data; Mucin-1; Mutant Proteins; Mutation; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyruvate Kinase; Rats | 2011 |
The family-wide structure and function of human dual-specificity protein phosphatases.
Topics: Catalytic Domain; Crystallography, X-Ray; Cysteine; Dual-Specificity Phosphatases; Enzyme Inhibitors; Escherichia coli; Humans; Hydrolysis; Models, Molecular; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Phosphotyrosine; Phylogeny; Protein Structure, Secondary; Recombinant Proteins; Signal Transduction; Structural Homology, Protein; Substrate Specificity | 2014 |
Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Benzothiepins; Catalytic Domain; Cell Death; Cerebral Cortex; Cognition Disorders; Cysteine; Disease Models, Animal; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Neurons; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases, Non-Receptor; Substrate Specificity | 2014 |
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding.
Topics: Amino Acid Motifs; Binding Sites; Cysteine; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Models, Molecular; Oxidation-Reduction; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; Small Molecule Libraries; src Homology Domains; Sulfhydryl Compounds; Syk Kinase; ZAP-70 Protein-Tyrosine Kinase | 2015 |
Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation.
Topics: Acylation; Amino Acid Motifs; Amino Acid Sequence; Animals; Biocatalysis; Caveolin 2; Cell Line; Cysteine; Fatty Acids; Gene Knockdown Techniques; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Space; Lipoylation; Mice; Mitogens; Models, Biological; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Transport; Protein-Tyrosine Kinases; Rats; Signal Transduction; Substrate Specificity | 2015 |
Inhibition of STAT3 by Anticancer Drug Bendamustine.
Topics: Alanine; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Binding Sites; Cell Line, Tumor; Cysteine; Drug Screening Assays, Antitumor; Gene Expression; Humans; Peptides; Phosphotyrosine; Point Mutation; Protein Binding; src Homology Domains; STAT3 Transcription Factor; Structure-Activity Relationship | 2017 |