phosphoserine has been researched along with wortmannin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (45.45) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parry, R; Sansom, D; Ward, S; Westwick, J; Wilson, A | 1 |
| Goldstein, BJ; Li, PM | 1 |
| del Peso, L; González-García, M; Herrera, R; Nuñez, G; Page, C | 1 |
| Barker, SA; Caldwell, KK; Pfeiffer, JR; Wilson, BS | 1 |
| Cengel, KA; Freund, GG; Godbout, JP | 1 |
| Sakurada, K; Sasaki, Y; Seto, M | 1 |
| Birnbaum, MJ; Brozinick, JT | 1 |
| Anderson, S; Brennan, P; Higashi, K; Raven, C; Vanhaesebroeck, B; Ward, SG; Waterfield, MD; Welham, M | 1 |
| Cichy, SC; Cohen, P; Guo, S; Rena, G; Unterman, TG | 1 |
| Brandt, SJ; Koury, MJ; Prasad, KS; Tang, T | 1 |
| Heads, RJ; Marber, MS; Mockridge, JW | 1 |
| Pelling, JC; Persons, DL; Yazlovitskaya, EM | 1 |
| Capitani, S; Mazzoni, M; Milani, D; Mirandola, P; Miscia, S; Secchiero, P; Zauli, G | 1 |
| Chung, J; Jee, K; Kim, D; Kim, S; Koh, H | 1 |
| Chen, ZP; Harris, MB; Ju, H; Kemp, BE; Liang, H; Michell, BJ; Venema, RC; Venema, VJ; Zou, R | 1 |
| Felts, N; Floyd, RA; Hensley, K; Pye, QN; Salsman, S | 1 |
| Boo, YC; Boyd, N; Du, J; Jo, H; Shiojima, I; Sorescu, G; Walsh, K | 1 |
| Alfonso, M; Campbell, DG; Cohen, P; Mora, A; Murray, JT; Peggie, M | 1 |
| Bhattacharya, S; Johnson, LR; Ray, RM | 1 |
| Bonner, C; Byrne, MM; Nolan, JJ; Prehn, JH; Wobser, H | 1 |
| Barrett, EJ; Chai, W; Liu, Z; Wang, AX; Wang, H | 1 |
| Cho, SJ; Choi, JS; Kim, HY; Lee, SK; Lee, WH; Park, BD; Park, JH; Surh, YJ | 1 |
22 other study(ies) available for phosphoserine and wortmannin
| Article | Year |
|---|---|
The phosphoinositide 3-kinase inhibitor wortmannin inhibits CD28-mediated T cell co-stimulation.
Topics: Androstadienes; Animals; CD28 Antigens; Cell Line; CHO Cells; Cricetinae; Enzyme Inhibitors; Humans; Lymphocyte Activation; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; T-Lymphocytes; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1995 |
Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells.
Topics: Androstadienes; Animals; Cell Line; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver Neoplasms, Experimental; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Rats; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1996 |
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.
Topics: Androstadienes; Animals; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cell Line; Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-3; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Signal Transduction; Wortmannin | 1997 |
Wortmannin-sensitive phosphorylation, translocation, and activation of PLCgamma1, but not PLCgamma2, in antigen-stimulated RBL-2H3 mast cells.
Topics: Androstadienes; Animals; Antigens; Biological Transport; Cell Membrane; Dinitrophenols; Enzyme Activation; Enzyme Inhibitors; Golgi Apparatus; Inositol 1,4,5-Trisphosphate; Isoenzymes; Leukemia, Basophilic, Acute; Mast Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptors, IgE; Serum Albumin, Bovine; Tumor Cells, Cultured; Type C Phospholipases; Wortmannin | 1998 |
Phosphatidylinositol 3'-kinase is associated with a serine kinase that is activated by okadaic acid.
Topics: Androstadienes; Blotting, Western; Enzyme Inhibitors; Humans; Multiple Myeloma; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Precipitin Tests; Protein Serine-Threonine Kinases; Tumor Cells, Cultured; Wortmannin | 1998 |
Dynamics of myosin light chain phosphorylation at Ser19 and Thr18/Ser19 in smooth muscle cells in culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Aorta; Azepines; Blotting, Western; Cell Line; Dinoprost; Enzyme Inhibitors; Kinetics; Mice; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Phosphoserine; Phosphothreonine; Rabbits; Staurosporine; Wortmannin | 1998 |
Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle.
Topics: Androstadienes; Animals; Biological Transport; Enzyme Activation; Enzyme Inhibitors; Glucose; Insulin; Male; Muscle Contraction; Muscle, Skeletal; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; Signal Transduction; Wortmannin | 1998 |
Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo.
Topics: Amino Acid Sequence; Androstadienes; Binding Sites; CD28 Antigens; Chromones; Down-Regulation; Humans; Jurkat Cells; Molecular Sequence Data; Morpholines; Mutation; Peptide Mapping; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphopeptides; Phosphorylation; Phosphoserine; Recombinant Proteins; Sequence Alignment; Signal Transduction; Wortmannin | 1999 |
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Androstadienes; Antibody Specificity; bcl-Associated Death Protein; Caenorhabditis elegans Proteins; Carrier Proteins; Consensus Sequence; DNA-Binding Proteins; Enzyme Activation; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Insulin-Like Growth Factor I; Molecular Sequence Data; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Serine; Signal Transduction; Sirolimus; Threonine; Transcription Factors; Wortmannin | 1999 |
Mitogen-activated protein kinase mediates erythropoietin-induced phosphorylation of the TAL1/SCL transcription factor in murine proerythroblasts.
Topics: Androstadienes; Anemia; Animals; Basic Helix-Loop-Helix Transcription Factors; DNA-Binding Proteins; Enzyme Inhibitors; Erythroblasts; Flavonoids; Friend murine leukemia virus; Hematopoietic Stem Cells; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphopeptides; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Recombinant Proteins; Spleen; T-Cell Acute Lymphocytic Leukemia Protein 1; Transcription Factors; Wortmannin | 1999 |
Activation of Akt during simulated ischemia/reperfusion in cardiac myocytes.
Topics: Androstadienes; Animals; Animals, Newborn; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Genistein; Imidazoles; Kinetics; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Pyridines; Rats; Retroviridae Proteins, Oncogenic; Wortmannin | 2000 |
Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin.
Topics: Androstadienes; Animals; Caffeine; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphorylation; Phosphoserine; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Pyridines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Wortmannin | 2000 |
HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Androstadienes; Animals; Cattle; Chromones; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Gene Expression Regulation; Gene Products, tat; HIV-1; Morpholines; Neurons; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Serum Albumin, Bovine; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Transfection; Wortmannin | 2001 |
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Androstadienes; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Kinetics; MAP Kinase Signaling System; Mice; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulation.
Topics: Androstadienes; Animals; Aorta; Bradykinin; Calcineurin Inhibitors; Cattle; Chromones; Cyclosporine; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Kinetics; Morpholines; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Wortmannin | 2001 |
Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN.
Topics: Acetylcysteine; Androstadienes; Animals; Antimycin A; Astrocytes; Blotting, Western; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Hydrogen Peroxide; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rotenone; Signal Transduction; Tumor Suppressor Proteins; Uncoupling Agents; Wortmannin | 2001 |
Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.
Topics: Adenoviridae; Androstadienes; Animals; Aorta, Thoracic; Cattle; Cell Transformation, Viral; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Kinetics; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Stress, Mechanical; Wortmannin | 2002 |
Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Androstadienes; Animals; Antibody Specificity; Benzamides; Cell Extracts; Cell Line; Contractile Proteins; Epidermal Growth Factor; Filamins; Humans; Immediate-Early Proteins; Insulin; Isoenzymes; Mice; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Muscle, Skeletal; Myoblasts; Myocardium; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Signal Transduction; Sirolimus; Substrate Specificity; Wortmannin | 2004 |
Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kappaB activation but not GSK3beta activity.
Topics: Androstadienes; Animals; Apoptosis; bcl-Associated Death Protein; Caspase 3; Caspase 9; Cell Line; Cell Nucleus; Chromones; Eflornithine; Enzyme Activation; Genes, Dominant; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; I-kappa B Proteins; Morpholines; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Polyamines; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Tumor Necrosis Factor-alpha; Wortmannin | 2005 |
Downregulation of protein kinase B/Akt-1 mediates INS-1 insulinoma cell apoptosis induced by dominant-negative suppression of hepatocyte nuclear factor-1alpha function.
Topics: Androstadienes; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Hepatocyte Nuclear Factor 1-alpha; Insulinoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoserine; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Time Factors; Wortmannin | 2006 |
The trafficking/interaction of eNOS and caveolin-1 induced by insulin modulates endothelial nitric oxide production.
Topics: Acyltransferases; Androstadienes; Animals; Cattle; Caveolin 1; Cell Membrane; Endothelial Cells; Golgi Apparatus; Insulin; Lipoylation; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoserine; Protein Binding; Protein Transport; RNA, Small Interfering; Subcellular Fractions; Wortmannin | 2009 |
Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation.
Topics: Androstadienes; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Etoposide; Female; Ginsenosides; HeLa Cells; Humans; Korea; Liver Neoplasms; Medicine, East Asian Traditional; Membrane Potentials; Mitochondria; Mycotoxins; Phosphoserine; Stomach Neoplasms; Wortmannin | 2010 |