phosphoserine has been researched along with tyrosine in 189 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 67 (35.45) | 18.7374 |
| 1990's | 110 (58.20) | 18.2507 |
| 2000's | 6 (3.17) | 29.6817 |
| 2010's | 3 (1.59) | 24.3611 |
| 2020's | 3 (1.59) | 2.80 |
| Authors | Studies |
|---|---|
| Gelman, MS; Hadcock, JR; Malbon, CC; Port, JD | 1 |
| Aaronson, SA; Bottaro, DP; Chan, A; Ishibashi, T; Miki, T | 1 |
| Heidecker, G; Kölch, W; Morrison, DK; Rapp, UR | 1 |
| Min, HK; Park, DJ; Rhee, SG | 1 |
| Bordwell, KL; Mooney, RA | 1 |
| Atherton-Fessler, S; Parker, LL; Piwnica-Worms, H | 1 |
| Li, P; Roberts, TM; Williams, NG | 1 |
| Afar, DE; Bell, JC; Ben-David, Y; Douville, EM; Howell, BW; Letwin, K; Pawson, T; Tannock, L | 1 |
| Baltensperger, K; Czech, MP; Lewis, RE; Ross, AH; Vissavajjhala, P; Woon, CW | 1 |
| Crews, CM; Erikson, RL | 1 |
| Baggio, B; Bordin, L; Clari, G; Moret, V | 1 |
| Farrar, WL; Linnekin, D; Park, LS | 1 |
| Chiang, TM | 1 |
| Abraham, RT; Dick, CJ; Einspahr, KJ; Leibson, PJ | 1 |
| Jensen, JL; Lamkin, MS; Oppenheim, FG; Troxler, RF | 1 |
| Bird, TA; Saklatvala, J | 1 |
| Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P | 1 |
| Anderson, SR; Malencik, DA; Zhao, ZZ | 1 |
| Clinton, GM; Li, SW; Lin, YZ | 1 |
| Granot, Y; Schrier, RW; Van Putten, V | 1 |
| Cozzone, AJ; Dadssi, M | 1 |
| Iwashita, S; Mitsui, K | 2 |
| App, H; Baccarini, M; Rapp, UR; Sabatini, DM; Stanley, ER | 1 |
| Farrar, WL; Linnekin, D | 1 |
| Carroll, MP; Clark-Lewis, I; May, WS; Rapp, UR | 1 |
| Biener, Y; Zick, Y | 1 |
| Ballou, LM; Luther, H; Thomas, G | 1 |
| Contreras, ML; Fink, D; Guroff, G; Kim, HS; Kim, UH; Park, DJ; Rhee, SG | 1 |
| Clack, B; Ellis, L; Tavaré, JM | 1 |
| Carroll, RB; Samad, A | 1 |
| Marshall, SH; Muñoz, G | 1 |
| Meggio, F; Perich, JW; Pinna, LA; Reynolds, EC | 1 |
| Bayer, H; Buchner, K; Hucho, F; Meyer, HE; Schroeder, W | 1 |
| Denton, RM; Issad, T; Tavaré, JM | 1 |
| Byun, SM; Kang, KR; Kang, YS; Kim, CW; Kim, YW | 1 |
| Abdel-Ghany, M; Koland, J; Racker, E; Revis-Gupta, S | 1 |
| Ahn, NG; Boulton, TG; Bratlien, RL; Cobb, MH; Ericsson, L; Krebs, EG; Panayotatos, N; Radziejewska, E; Seger, R; Yancopoulos, GD | 1 |
| Friedmann, M; Hoover, D; Magnuson, NS; Reeves, R | 1 |
| Kataoka, H; Makita, M; Sakiyama, N | 1 |
| Iqbal, K; Murthy, LR | 1 |
| Cohen, P; Gómez, N | 1 |
| Kole, HK; Lenard, J | 1 |
| Kamps, MP | 1 |
| Ringer, DP | 1 |
| Anderson, NG; Erickson, AK; Ray, LB; Sturgill, TW | 1 |
| Kaplan, NO; Knowles, AF; Leis, JF | 1 |
| Cohen, S; Sawyer, ST | 1 |
| Aitken, A; Morrice, N | 1 |
| Mueller-Lantzsch, N; Roeckel, D | 1 |
| Carlomagno, L; Huebner, VD; Matthews, HR | 1 |
| Hollenberg, MD; Pallen, CJ; Valentine, KA; Wang, JH | 1 |
| Londesborough, J | 1 |
| Bretscher, A; Cooper, JA; Gould, KL; Hunter, T | 1 |
| Rosen, OM; Stadtmauer, L | 1 |
| Casnellie, JE; Lamberts, RJ | 1 |
| Lau, AF | 1 |
| Ziemiecki, A | 1 |
| Bárány, K; Bárány, M; Csabina, S; Mougios, V | 1 |
| Hunter, T; Patschinsky, T; Sefton, BM | 1 |
| Bergeron, JJ; Kay, DG; Khan, MN; Lai, WH; Posner, BI; Uchihashi, M | 1 |
| Blumenthal, DK; Chan, CP; Gallis, B; Krebs, EG; Pallen, CJ; Wang, JH | 1 |
| Harford, JB; Klausner, RD; Patel, MD; Samelson, LE; Weissman, AM | 1 |
| Barbaric, S; Donella-Deana, A; Lopandic, K; Pinna, LA | 1 |
| Etheredge, RW; Glimcher, MJ | 1 |
| Bauer, H; Niemann, H; Simon, E; Snoek, GT; Tamura, T | 1 |
| Niedbalski, JS; Ringer, DP | 1 |
| Destrée, OH; Sluyser, M | 1 |
| Belzer, SK; Collett, MS | 1 |
| David-Pfeuty, T; Guesdon, F | 1 |
| Acquaviva, AM; Consiglio, E; De Luca, M; Formisano, S; Gallo, A; Liguoro, D; Santisteban, P; Shifrin, S; Vittorio, T; Yeh, HJ | 1 |
| Huang, ES; Muganda-Ojiaku, PM | 1 |
| Rosen, OM | 1 |
| Balasubramanian, AS; Panneerselvam, K; Ramamoorthy, S | 1 |
| Barel, M; Delcayre, AX; Fiandino, A; Frade, R | 1 |
| Clarke, S; Drickamer, K; Lou, LL; McFadden, PN | 1 |
| Amatruda, JM; Roncone, AM; Sparks, CE; Sparks, JD | 1 |
| Cooper, JA; Kazlauskas, A | 1 |
| Dasgupta, JD; Rudd, CE; Schlossman, SF; Trevillyan, JM; Wong, LL | 1 |
| Bernier, M; Laird, DM; Lane, MD | 1 |
| Colca, JR; McCroskey, MC; Pearson, JD | 1 |
| Johnson, PJ; Kmiecik, TE; Shalloway, D | 1 |
| Eigenbrodt, E; Presek, P; Reinacher, M | 1 |
| Sale, GJ; Smith, DM | 1 |
| Foster, R; Martin, GS; Thorner, J | 1 |
| Beachey, EH; Kotb, M | 1 |
| Hunter, T; Meisenhelder, J; Rhee, SG; Suh, PG | 1 |
| Boland, D; Goren, HJ; Neufeld, E | 1 |
| Gjika, HB; Levine, L; Van Vunakis, H | 1 |
| Acuto, O; Alcover, A; Danielian, S; Fagard, R; Fischer, S | 1 |
| Dass, C | 1 |
| Henschen, A; Lucas, J | 1 |
| Kahn, CR; Takayama, S; White, MF | 1 |
| Clinton, GM; Huang, AS | 1 |
| Sen, A | 1 |
| Berdot, C; Elliott, T; Hunter, T; Patschinsky, T; Sefton, BM | 1 |
| Blith, DL; Häring, HU; Kahn, CR; Karlsson, FA; Kasuga, M; Zick, Y | 1 |
| Adkins, B; Hunter, T; Sefton, BM | 1 |
| Fujitaki, JM; Smith, RA; Yang, JC | 1 |
| Cozzone, AJ; Manai, M | 1 |
| Kaplan, NO; Leis, JF | 1 |
| Congote, LF | 1 |
| Capony, JP; Demaille, JG | 1 |
| Brugge, JS; Darrow, D; Lipsich, LA; Yonemoto, W | 1 |
| Chang, WC; Chou, CK; Lee, ML; Lee, SC | 1 |
| Gootwine, E; Hortsch, M; Schlessinger, J; Webb, CG | 1 |
| Buss, JE; Stull, JT | 1 |
| Fehlmann, M; Gazzano, H; Kowalski, A; Van Obberghen, E | 1 |
| Foulkes, JG | 1 |
| Erikson, RL | 1 |
| Dasgupta, JD; Garbers, DL; Swarup, G | 1 |
| Auricchio, F; Migliaccio, A; Rotondi, A | 1 |
| Martensen, TM | 1 |
| Fukunaga, R; Nagata, S; Pan, CX; Yonehara, S | 1 |
| Liu, WK; Yang, SD; Yen, SH; Yu, JS | 1 |
| Hakomori, S; Igarashi, Y; Kitamura, K; Zhou, Q | 1 |
| Donella-Deana, A; Klee, C; Krinks, MH; Pinna, LA; Ruzzene, M | 1 |
| Berti, L; Häring, H; Kellerer, M; Kroder, G; Mosthaf, L; Mushack, J; Seedorf, K; Seffer, E; Tippmer, S | 1 |
| King, SM; Witman, GB | 1 |
| Pratt, MM; Salathe, M; Wanner, A | 1 |
| Huganir, RL; Wagner, KR | 1 |
| Berk, BC; Bernstein, KE; Delafontaine, P; Klein, JD; Marrero, MB; Paxton, WG | 1 |
| Anderson, MT; Gitler, C; Herzenberg, LA; Staal, FJ; Staal, GE | 1 |
| Daya-Makin, M; Hogg, JC; Lipp, M; Mogentale, TL; Parchomchuk, J; Pelech, SL; Sanghera, JS | 1 |
| DePaoli-Roach, AA; Fiol, CJ; Roach, PJ; Wang, QM | 1 |
| Fallon, RJ; Perlmutter, DH; Sippel, CJ | 1 |
| Banville, D; Bouchard, P; Dumas, F; Fischer, EH; Shen, SH; Zhao, Z | 1 |
| Stover, DR; Walsh, KA | 1 |
| Damuni, Z; Li, M; Xiong, H | 1 |
| Heegaard, NH | 1 |
| Benjamin, CW; Jones, DA; Linseman, DA | 1 |
| Ali, N; Chua, NH; Halfter, U | 1 |
| Casey, M; Pai, LM; Peifer, M | 1 |
| Cherqui, G; Plas, C; Zachayus, JL | 1 |
| Abu-Lawi, KI; Sultzer, BM | 1 |
| Hoffmann, R; Kalbitzer, HR; Reichert, I; Wachs, WO; Zeppezauer, M | 1 |
| Marshall, SH; Muñoz, GE | 1 |
| Caldenhoven, E; Coffer, P; Heinrich, PC; Horn, F; Kruijer, W; Lütticken, C; Schindler, C; Schwartz, C; Yuan, J | 1 |
| Kinsey, WH | 1 |
| Giasson, E; Meloche, S | 1 |
| Adam, LP; Gunst, SJ; Pavalko, FM; Walker, TL; Wu, MF | 1 |
| Kumar, R | 1 |
| Pillay, I; Sharma, SV | 1 |
| Khan, MA; Kobayashi, S; Nakagawa, H; Okada, M; Okumura, N | 1 |
| Hoffman, FJ; Roder, HM; Schröder, W | 1 |
| Fabian, H; Lang, E; Mantsch, HH; Otvos, L; Szendrei, GI | 1 |
| Barlati, S; Bona, C; De Petro, G; Paracini, F; Tonelli, M | 1 |
| Hunter, T; Tracy, S; van der Geer, P | 1 |
| Fujiki, N; Hamaguchi, M; Miyadai, T; Mutoh, T; Tokuda, A | 1 |
| Lacombe, JM; Mora, N; Pavia, AA | 1 |
| Benarous, R; Bodéus, M; Bougeret, C; Marie-Cardine, A; Ramos-Morales, F | 1 |
| Cuveele, JF; de Witte, PA; Merlevede, WJ; Vandenheede, JR | 1 |
| Asamoah, KA; Carter, WG; Sale, GJ | 1 |
| Darnell, JE; Wen, Z; Zhong, Z | 1 |
| Maloy, S; Ostrovsky, PC | 1 |
| Biesinger, B; Desrosiers, RC; Friedrich, U; Jun, T; Jung, JU; Lang, SM; Roberts, TM | 1 |
| Parry, R; Sansom, D; Ward, S; Westwick, J; Wilson, A | 1 |
| Ploegh, HL; Schaap, D; van Blitterswijk, WJ; van der Bend, RL; van der Wal, J | 1 |
| Cleghon, V; Kaplan, DR; Rabin, SJ | 1 |
| Coleman, TR; Dunphy, WG; Tang, Z | 1 |
| Inagami, T; Nakajo, S | 1 |
| Blackstone, CD; Huganir, RL; Moss, SJ | 1 |
| Donella-Deana, A; Eisermann, B; Heber, M; Hoffmann-Posorske, E; Hutton, T; Korte, H; Meyer, HE; Perich, JW; Wegner, A; Weigt, C | 1 |
| Kataoka, H; Makita, M; Nakai, K | 1 |
| Bell, SM; Connolly, DC; Degen, JL; Maihle, NJ | 1 |
| Livingston, JN; Moss, AM | 1 |
| Egelhoff, TT; Lee, RJ; Spudich, JA | 1 |
| Elizarov, SM; Preobrazhensky, AA | 1 |
| Goldberg, GS; Lau, AF | 1 |
| Decker, T; Eilers, A; Georgellis, D; Harpur, AG; Klose, B; Schindler, C; Wilks, AF; Ziemiecki, A | 1 |
| Dietrich, J; Geisler, C; Hou, X; Wegener, AM | 1 |
| Goldstein, BJ; Li, PM | 1 |
| Borowski, P; Heiland, M; Kornetzky, L; Laufs, R; Roloff, S; Weber, W | 1 |
| Fink, BD; Grunwald, GB; Lee, MM | 1 |
| Alessi, DR; Cohen, P; Shaw, M | 1 |
| Guesdon, F; Knight, CG; Rawlinson, LM; Saklatvala, J | 1 |
| Corbin, J; Imagawa, T; Kaya, S; Kikkawa, U; Mårdh, S; Mori, M; Shimada, A; Taniguchi, K; Togawa, K | 1 |
| Kahn, CR; Kriauciunas, KM; Myers, MG | 1 |
| Alber, F; Carloni, P; Dal Peraro, M | 1 |
| Guthridge, MA; Lindeman, GJ; Lopez, AF; Olayioye, MA; Stomski, FC; Visvader, JE | 1 |
| Kristjánsdóttir, K; Rudolph, J; Safi, A; Shah, C | 1 |
| Andon, NL; Ghosh, SS; Hsieh, A; Sun, C; Taylor, SW | 1 |
| Riemen, AJ; Waters, ML | 1 |
| Allen, JK; Armaiz-Pena, GN; Bar-Eli, M; Cole, SW; Cruz, A; De Geest, K; Deavers, MT; English, RD; Gallick, GE; Gharpure, KM; Han, LY; Jackson, DB; Lin, YG; Lopez, GE; Lopez-Berestein, G; Lutgendorf, SK; Mangala, LS; Nagaraja, AS; Nick, AM; Rodriguez-Aguayo, C; Shahzad, MM; Shazhad, MM; Soldatos, TG; Soman, KV; Sood, AK; Stone, RL; Torres-Lugo, M; Villares, GJ; Vivas-Mejia, P; Wiktorowicz, JE; Wu, Z; Young, T; Zien, A; Zigler, M | 1 |
| Klerman, H; Levine, E; McClendon, CL; Rapp, C | 1 |
| Cesaro, L; Pinna, LA | 1 |
| Hinton, SD | 1 |
| Duan, J; He, C; Si, C; Teixeira da Silva, JA; Yu, Z; Zeng, D; Zhang, J | 1 |
| Guo, C; Mattingly, RR; Rosenspire, AJ; Stemmer, PM | 1 |
6 review(s) available for phosphoserine and tyrosine
| Article | Year |
|---|---|
The role of Raf-1 phosphorylation in signal transduction.
Topics: Amino Acid Sequence; Animals; Cell Division; Enzyme Activation; Growth Substances; Humans; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptors, Cell Surface; Serine; Signal Transduction; Substrate Specificity; Threonine; Tyrosine | 1992 |
After insulin binds.
Topics: DNA; Drosophila; ErbB Receptors; Humans; Insulin; Molecular Weight; Oncogenes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Cell Surface; Substrate Specificity; Tyrosine | 1987 |
Phosphotyrosyl-protein phosphatases.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Cell Transformation, Viral; Oncogenes; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Retroviridae; Tyrosine | 1983 |
Strategies for nonradioactive methods in the localization of phosphorylated amino acids in proteins.
Topics: Amino Acid Sequence; Amino Acids; Mass Spectrometry; Molecular Sequence Data; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1993 |
The generation of phosphoserine stretches in phosphoproteins: mechanism and significance.
Topics: Casein Kinase I; Casein Kinase II; Glycogen Synthase Kinase 3; Humans; Phosphoproteins; Phosphoserine; Threonine; Tyrosine | 2015 |
Pseudophosphatase MK-STYX: the atypical member of the MAP kinase phosphatases.
Topics: Animals; Humans; Mitogen-Activated Protein Kinase Phosphatases; Phosphoserine; Threonine; Tyrosine | 2020 |
183 other study(ies) available for phosphoserine and tyrosine
| Article | Year |
|---|---|
Cross-talk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of beta 2-adrenergic receptors in response to insulin.
Topics: Animals; Cell Line; Cricetinae; GTP-Binding Proteins; Insulin; Iodine Radioisotopes; Isoproterenol; Kinetics; Male; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Adrenergic, beta; Tyrosine; Vas Deferens | 1992 |
Expression cloning of a human dual-specificity phosphatase.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Gene Expression; Humans; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphoserine; Phosphotyrosine; Restriction Mapping; RNA, Messenger; Sequence Alignment; Substrate Specificity; Tyrosine | 1992 |
Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Kinetics; Muromonab-CD3; Peptide Mapping; Phosphates; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases; Tyrosine | 1992 |
Insulin stimulates the tyrosine phosphorylation of a 61-kilodalton protein in rat adipocytes.
Topics: Adipose Tissue; Animals; Cell Fractionation; Immunoblotting; Insulin; Male; Molecular Weight; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine | 1992 |
p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15.
Topics: CDC2 Protein Kinase; Cell Cycle Proteins; In Vitro Techniques; Nuclear Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Substrate Specificity; Tyrosine | 1992 |
Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase.
Topics: Animals; Cells, Cultured; Enzyme Activation; In Vitro Techniques; Moths; Oncogene Protein pp60(v-src); Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Tyrosine | 1992 |
Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Compartmentation; Cell Membrane; Cloning, Molecular; Cytoplasm; DNA; Gene Expression; In Vitro Techniques; Mice; Molecular Sequence Data; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; RNA, Messenger; Sequence Alignment; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1992 |
Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor.
Topics: Amino Acid Sequence; Humans; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Time Factors; Tyrosine | 1992 |
Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product.
Topics: Amino Acid Sequence; Animals; Enzyme Activation; Fungal Proteins; Genes; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Recombinant Proteins; Sequence Alignment; Tyrosine | 1992 |
Tyrosine-protein kinase inhibition in human erythrocytes by polyphosphoinositides (PIP and PIP2).
Topics: Adenosine Triphosphate; Anion Exchange Protein 1, Erythrocyte; Chymotrypsin; Erythrocytes; Humans; Hydrogen-Ion Concentration; Peptide Fragments; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1992 |
Dissociation of human cytokine receptor expression and signal transduction.
Topics: Cell Division; Dimethyl Sulfoxide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-3; Signal Transduction; Tretinoin; Tumor Cells, Cultured; Tyrosine | 1992 |
Okadaic acid and vanadate inhibit collagen-induced platelet aggregation; the functional relation of phosphatases on platelet aggregation.
Topics: Adenosine Triphosphate; Blood Platelets; Collagen; Depression, Chemical; Ethers, Cyclic; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Phosphatase 1; Serotonin; Tyrosine; Vanadates | 1992 |
Interleukin-2 signal transduction in human NK cells: multisite phosphorylation and activation of the tyrosine kinase p56lck.
Topics: Cells, Cultured; Enzyme Activation; Humans; In Vitro Techniques; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1992 |
Multiple forms of statherin in human salivary secretions.
Topics: Adsorption; Amino Acid Sequence; Amino Acids; Chromatography, Gel; Chromatography, High Pressure Liquid; Durapatite; Humans; Hydroxyapatites; Molecular Sequence Data; Phenylalanine; Phosphoserine; Salivary Proteins and Peptides; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1991 |
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 1990 |
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody.
Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
Determination of dityrosine, phosphotyrosine, phosphothreonine, and phosphoserine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Microchemistry; p-Dimethylaminoazobenzene; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Serine; Threonine; Tyrosine | 1990 |
Insulin and epidermal growth factor stimulate phosphorylation of p185HER-2 in the breast carcinoma cell line, BT474.
Topics: Blood; Breast Neoplasms; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, ErbB-2; Tumor Cells, Cultured; Tyrosine | 1990 |
Vasopressin dependent tyrosine phosphorylation of a 38 kDa protein in human platelets.
Topics: Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Platelets; Blotting, Western; Colforsin; Dose-Response Relationship, Drug; Electrophoresis; Humans; In Vitro Techniques; Phorbol Esters; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Vasopressin; Time Factors; Tyrosine | 1990 |
Occurrence of protein phosphorylation in various bacterial species.
Topics: Adenosine Triphosphate; Arthrobacter; Bacillus; Bacillus megaterium; Bacteria; Bacterial Proteins; Cyclic AMP; Cyclic GMP; Escherichia coli; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Pseudomonas; Tyrosine | 1990 |
Examination of the role of serine phosphorylation in phospholipase C-gamma and its related P47 in cAMP-mediated depression of epidermal growth factor signal transduction.
Topics: Colforsin; Cross Reactions; Epidermal Growth Factor; ErbB Receptors; Humans; In Vitro Techniques; Molecular Weight; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1990 |
[Phosphoamino acid analysis by 2-dimensional electrophoresis].
Topics: Electrophoresis, Gel, Two-Dimensional; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1990 |
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product.
Topics: Amino Acid Sequence; Animals; In Vitro Techniques; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Molecular Sequence Data; Oligopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptor, Macrophage Colony-Stimulating Factor; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Temperature; Tyrosine | 1990 |
Signal transduction of human interleukin 3 and granulocyte-macrophage colony-stimulating factor through serine and tyrosine phosphorylation.
Topics: Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Isoenzymes; Kinetics; Phosphates; Phosphoserine; Phosphotyrosine; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
Interleukin-3 and granulocyte-macrophage colony-stimulating factor mediate rapid phosphorylation and activation of cytosolic c-raf.
Topics: Animals; Cell Line; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Immunosorbent Techniques; Interleukin-3; Kinetics; Mice; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Tyrosine | 1990 |
Basic polycations activate the insulin receptor kinase and a tightly associated serine kinase.
Topics: Animals; Cattle; Cell Membrane; Enzyme Activation; In Vitro Techniques; Liver; Macromolecular Substances; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Polyamines; Polyelectrolytes; Polylysine; Polymers; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Rod Cell Outer Segment; Tyrosine | 1990 |
MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways.
Topics: Adipose Tissue; Animals; Blood; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Reactivators; Epidermal Growth Factor; Fibroblasts; Insulin; Mice; Oocytes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Tyrosine; Xenopus | 1991 |
Nerve growth factor stimulates phosphorylation of phospholipase C-gamma in PC12 cells.
Topics: Animals; Blotting, Western; Cells, Cultured; Epidermal Growth Factor; In Vitro Techniques; Isoenzymes; Nerve Growth Factors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Type C Phospholipases; Tyrosine | 1991 |
Two-dimensional phosphopeptide analysis of the autophosphorylation cascade of a soluble insulin receptor tyrosine kinase. The tyrosines phosphorylated are typical of those observed following phosphorylation of the heterotetrameric insulin receptor in inta
Topics: Amino Acid Sequence; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptide Mapping; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Trypsin; Tyrosine | 1991 |
The tumor suppressor p53 is bound to RNA by a stable covalent linkage.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Genes, Tumor Suppressor; Mice; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphotyrosine; Rats; Ribonucleoproteins; RNA; Tumor Suppressor Protein p53; Tyrosine | 1991 |
An alternative method for a fast separation of phosphotyrosine.
Topics: Adenosine Triphosphate; Animals; Chromatography, Thin Layer; Cytidine Monophosphate; Humans; Liver; Lymphocytes; Mice; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine; Uridine Monophosphate | 1990 |
Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase.
Topics: Amino Acid Sequence; Animals; Casein Kinases; Cell Division; Cytosol; Kinetics; Liver; Molecular Sequence Data; Oligopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Substrate Specificity; Tyrosine | 1991 |
Phosphorylation sites of the nicotinic acetylcholine receptor. A novel site detected in position delta S362.
Topics: Animals; Chromatography, High Pressure Liquid; Enzyme Activation; Phosphates; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Receptors, Nicotinic; Torpedo; Tyrosine | 1991 |
Analysis of insulin receptor phosphorylation sites in intact rat liver cells by two-dimensional phosphopeptide mapping. Predominance of the tris-phosphorylated form of the kinase domain after stimulation by insulin.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Insulin; Liver; Male; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine | 1991 |
Elongation factor-2 in chick embryo is phosphorylated on tyrosine as well as serine and threonine.
Topics: Age Factors; Animals; Chick Embryo; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Subcellular Fractions; Tyrosine | 1991 |
Heparin stimulates epidermal growth factor receptor-mediated phosphorylation of tyrosine and threonine residues.
Topics: Amino Acids; Animals; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Escherichia coli; Glutathione Transferase; Heparin; Humans; Insecta; Manganese; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine | 1991 |
Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Enzyme Activation; Insulin; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Recombinant Proteins; Sequence Homology, Nucleic Acid; Tyrosine | 1991 |
Recombinant human pim-1 protein exhibits serine/threonine kinase activity.
Topics: Cloning, Molecular; DNA; Escherichia coli; Humans; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Recombinant Proteins; Substrate Specificity; Tyrosine | 1991 |
Distribution and contents of free O-phosphoamino acids in animal tissues.
Topics: Animals; Brain Chemistry; Chickens; Chromatography, Gas; Fishes; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Myocardium; Organ Specificity; Phosphoserine; Phosphothreonine; Phosphotyrosine; Species Specificity; Swine; Tyrosine | 1991 |
Measurement of picomoles of phosphoamino acids by high-performance liquid chromatography.
Topics: Amino Acids; Caseins; Chromatography, High Pressure Liquid; Organophosphorus Compounds; Phosphoserine; Phosphothreonine; Phosphotyrosine; Reproducibility of Results; Serum Albumin, Bovine; Tyrosine | 1991 |
Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Antigens, CD; Enzyme Activation; Histocompatibility Antigens; In Vitro Techniques; Leukocyte Common Antigens; Nerve Growth Factors; Neurons; Pheochromocytoma; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Rats; Receptor, trkA; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1991 |
Insulin-induced stimulation of protein phosphorylation in Neurospora crassa cells.
Topics: Antibodies; Autoradiography; Fungal Proteins; Immunosorbent Techniques; Insulin; Membrane Proteins; Neurospora crassa; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphotyrosine; Receptor, Insulin; Tyrosine | 1991 |
Determination of phosphoamino acid composition by acid hydrolysis of protein blotted to Immobilon.
Topics: Amino Acids; Chromatography, Gel; Hydrolysis; Membranes, Artificial; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphotyrosine; Polyvinyls; Radioisotope Dilution Technique; Sulfur Radioisotopes; Tyrosine | 1991 |
Separation of phosphotyrosine, phosphoserine, and phosphothreonine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1991 |
Purification of mitogen-activated protein kinase from epidermal growth factor-treated 3T3-L1 fibroblasts.
Topics: 3T3 Cells; Animals; Autoradiography; Buffers; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Indicators and Reagents; Kinetics; Mice; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1991 |
Demonstration of separate phosphotyrosyl- and phosphoseryl- histone phosphatase activities in the plasma membranes of a human astrocytoma.
Topics: 4-Nitrophenylphosphatase; Astrocytoma; Cell Line; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Diphosphates; Histones; Humans; Hydrolysis; In Vitro Techniques; Nitrophenols; Nucleotides; Organophosphorus Compounds; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Tissue Distribution; Tyrosine; Vanadates; Vanadium | 1985 |
Epidermal growth factor stimulates the phosphorylation of the calcium-dependent 35,000-dalton substrate in intact A-431 cells.
Topics: Animals; Autoradiography; Calcium; Cell Line; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Mice; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proteins; Time Factors; Tyrosine | 1985 |
A simple and rapid method of quantitative analysis of phosphoamino acids by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1985 |
Biochemical characterization of two Epstein-Barr virus early antigen-associated phosphopolypeptides.
Topics: Antibodies, Monoclonal; Antigens, Viral; Cell Line; Chromatin; DNA; DNA-Binding Proteins; Herpesvirus 4, Human; Humans; Molecular Weight; Phosphopeptides; Phosphoserine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Tyrosine; Viral Proteins | 1985 |
Rapid separation of phosphoamino acids including the phosphohistidines by isocratic high-performance liquid chromatography of the orthophthalaldehyde derivatives.
Topics: Aldehydes; Amino Acids; Arginine; Buffers; Chromatography, High Pressure Liquid; Histidine; o-Phthalaldehyde; Organophosphorus Compounds; Phosphoserine; Phosphothreonine; Phosphotyrosine; Temperature; Tyrosine | 1985 |
Calcineurin-mediated dephosphorylation of the human placental membrane receptor for epidermal growth factor urogastrone.
Topics: Brain; Calmodulin-Binding Proteins; Cations, Monovalent; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Kinetics; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Pregnancy; Receptors, Cell Surface; Tyrosine | 1985 |
Phosphorylation of proteins in Clostridium thermohydrosulfuricum.
Topics: Bacterial Proteins; Calmodulin; Cell-Free System; Clostridium; Hexosephosphates; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyamines; Subcellular Fractions; Tyrosine | 1986 |
The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.
Topics: Animals; Carrier Proteins; Cell Line; Cytoskeletal Proteins; Fluorescent Antibody Technique; Humans; Isoelectric Point; Microfilament Proteins; Microvilli; Molecular Weight; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Subcellular Fractions; Tissue Distribution; Tyrosine | 1986 |
Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Cell Line; Colforsin; Cyclic AMP; Lymphocytes; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Receptor, Insulin; Time Factors; Tyrosine | 1986 |
Tumor promoters cause changes in the state of phosphorylation and apparent molecular weight of a tyrosine protein kinase in T lymphocytes.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Immunologic Techniques; Immunosorbent Techniques; Lymphoma; Mice; Molecular Weight; Phorbols; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Phosphotyrosine-containing 120,000-dalton protein coimmunoprecipitated with pp60v-src from Rous sarcoma virus-transformed mammalian cells.
Topics: Animals; Arvicolinae; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Chemical Precipitation; Chick Embryo; Epitopes; Immune Sera; Mice; Molecular Weight; Muscle Proteins; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Retroviridae Proteins; Tyrosine; Vinculin | 1986 |
Characterization of the monomeric and complex-associated forms of the gag-onc fusion proteins of three isolates of feline sarcoma virus: phosphorylation, kinase activity, acylation, and kinetics of complex formation.
Topics: Acylation; Animals; Cats; Cells, Cultured; Fibroblasts; Gene Products, gag; Kinetics; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae; Retroviridae Proteins; Sarcoma Viruses, Feline; Tyrosine | 1986 |
Characterization of the phosphorylatable myosin light chain in rat uterus.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Female; Isoelectric Point; Molecular Weight; Myosins; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Tyrosine; Uterus | 1986 |
Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chickens; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Retroviridae Proteins; Species Specificity; Tyrosine; Vanadium | 1986 |
Epidermal growth factor receptor kinase translocation and activation in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Golgi Apparatus; Kinetics; Liver; Male; Microscopy, Electron; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Tyrosine | 1986 |
Characterization of the phosphotyrosyl protein phosphatase activity of calmodulin-dependent protein phosphatase.
Topics: Amino Acid Sequence; Animals; Brain; Calmodulin; Cattle; Fluorides; Kinetics; Manganese; Myocardium; Myosins; Nickel; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Serine; Tyrosine; Vanadates; Vanadium; Zinc | 1986 |
Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor.
Topics: Animals; Antigens; Isoelectric Point; Lymphocyte Activation; Macromolecular Substances; Membrane Proteins; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Distinct specificities of repressible acid phosphatase from yeast toward phosphoseryl and phosphotyrosyl phosphopeptides.
Topics: Acid Phosphatase; Amino Acid Sequence; Isoenzymes; Kinetics; Phosphoproteins; Phosphoserine; Phosphotyrosine; Saccharomyces cerevisiae; Substrate Specificity; Tyrosine | 1986 |
Resolution and identification of O-phosphoserine, O-phosphothreonine, O-phosphotyrosine, and gamma-carboxyglutamic acid as their fluorescent o-phthalaldehyde derivatives by high performance liquid chromatography.
Topics: 1-Carboxyglutamic Acid; Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; o-Phthalaldehyde; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1986 |
gp140v-fms molecules expressed at the surface of cells transformed by the McDonough strain of feline sarcoma virus are phosphorylated in tyrosine and serine.
Topics: Animals; Cats; Cell Transformation, Neoplastic; Genes; Genes, Viral; Oncogene Protein gp140(v-fms); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Retroviridae; Retroviridae Proteins; Serine; Tyrosine; Vanadates; Vanadium | 1986 |
Separation and quantitative analysis of O-linked phosphoamino acids by isocratic high-performance liquid chromatography of the 9-fluorenylmethyl chloroformate derivatives.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Fluorenes; Ion Exchange Resins; Organophosphorus Compounds; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1986 |
Histone phosphorylation in explants of mouse mammary glands and tumors.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Histones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1986 |
Forms of pp60v-src isolated from Rous sarcoma virus-transformed cells.
Topics: Animals; Antibodies, Monoclonal; Arvicolinae; Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine; Vanadium | 1987 |
Epidermal growth factor stimulates serine and tyrosine phosphorylation in a 59-kD protein in purified plasma membranes from rat liver.
Topics: Animals; Endopeptidases; Epidermal Growth Factor; Liver; Male; Membrane Proteins; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Inbred Strains; Serine; Serine Endopeptidases; Tyrosine | 1987 |
Characterization of phosphate residues on thyroglobulin.
Topics: Animals; Carbohydrates; Cattle; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Mannose; Methionine; Phosphates; Phosphoserine; Phosphotyrosine; Pronase; Rats; Rats, Inbred F344; Thyroglobulin; Thyroid Gland; Tunicamycin; Tyrosine | 1987 |
Alteration of protein phosphorylation patterns in cell lines morphologically transformed by human cytomegalovirus.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cytomegalovirus; Humans; Isoelectric Point; Membrane Proteins; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Spermidine; Tyrosine | 1987 |
Phosphorylation of the lysosomal enzyme binding receptor protein from monkey brain and evidence for a tyrosine kinase activity associated with it.
Topics: Animals; Brain; Carrier Proteins; Histones; Intracellular Membranes; Lysosomes; Membrane Proteins; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, IGF Type 2; Tyrosine | 1987 |
gp140, the EBV/C3d receptor (CR2) of human B lymphocytes, is involved in cell-free phosphorylation of p120, a nuclear ribonucleoprotein.
Topics: B-Lymphocytes; Cell Nucleus; Herpesvirus 4, Human; Humans; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Precursors; Receptors, Complement; Receptors, Complement 3d; Receptors, Virus; Ribonucleoproteins; Tumor Cells, Cultured; Tyrosine | 1987 |
The stereospecificity of protein kinases.
Topics: Blood Proteins; Erythrocytes; Humans; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Stereoisomerism; Substrate Specificity; Tyrosine | 1987 |
Secretion of high and low molecular weight phosphorylated apolipoprotein B by hepatocytes from control and diabetic rats. Phosphorylation of APO BH and APO BL.
Topics: Animals; Apolipoproteins B; Cells, Cultured; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Liver; Male; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.
Topics: Animals; Cell Line; Immunoassay; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1988 |
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Electrophoresis, Polyacrylamide Gel; HIV; Humans; Hydrogen-Ion Concentration; Immunosorbent Techniques; Lymphocyte Activation; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Virus; T-Lymphocytes; Tyrosine | 1988 |
Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.
Topics: Adenosine Triphosphate; Adipose Tissue; Arsenicals; Cell Line; Deoxyglucose; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Insulin; Kinetics; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Trypsin; Tyrosine; Vanadates | 1988 |
Determination of [32P]phosphoamino acids in protein hydrolysates by isocratic anion-exchange high-performance liquid chromatography.
Topics: Buffers; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Serine; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1988 |
Regulation by the autophosphorylation site in overexpressed pp60c-src.
Topics: Animals; Mice; Mutation; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Structure-Activity Relationship; Tyrosine; Vanadium | 1988 |
Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Immunosorbent Techniques; Kinetics; Oncogene Protein pp60(v-src); Phosphoenolpyruvate; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Pyruvate Kinase; Retroviridae Proteins; Tyrosine | 1988 |
Characterization of sites of serine phosphorylation in human placental insulin receptor copurified with insulin-stimulated serine kinase activity by two-dimensional thin-layer peptide mapping.
Topics: Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Insulin; Serine; Tyrosine | 1989 |
Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria.
Topics: Electrophoresis, Gel, Two-Dimensional; Escherichia coli; Glutamate-Ammonia Ligase; Hydrolysis; Molecular Weight; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Radioisotope Dilution Technique; Salmonella typhimurium; Species Specificity; Tyrosine | 1989 |
Serine and tyrosine phosphorylation of 28- and 35-kDa proteins of human T lymphocytes stimulated by streptococcal M protein.
Topics: Antigens, Bacterial; Antigens, Differentiation, T-Lymphocyte; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Humans; Lymphocyte Activation; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Phytohemagglutinins; Serine; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Tyrosine | 1989 |
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro.
Topics: Animals; Blotting, Western; Cell Line; ErbB Receptors; Humans; Mice; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Precipitin Tests; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Time Factors; Type C Phospholipases; Tyrosine | 1989 |
Thin-layer chromatography can resolve phosphotyrosine, phosphoserine, and phosphothreonine in a protein hydrolyzate.
Topics: Animals; Autoradiography; Chromatography, Thin Layer; Humans; Hydrolysis; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1989 |
Antibodies and radioimmunoassays for phosphoserine, phosphothreonine and phosphotyrosine. Serologic specificities and levels of the phosphoamino acids in cytoplasmic fractions of rat tissues.
Topics: Animals; Antibodies; Antibody Specificity; Chromatography, Ion Exchange; Cytoplasm; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred F344; Serine; Serum Albumin, Bovine; Threonine; Tyrosine | 1989 |
The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2.
Topics: Antigens, Differentiation, T-Lymphocyte; Blotting, Western; CD2 Antigens; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Weight; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Receptors, Immunologic; T-Lymphocytes; Time Factors; Tyrosine | 1989 |
Characterization of phosphorylated amino acids by fast-atom bombardment mass spectrometry.
Topics: Phosphoserine; Phosphothreonine; Phosphotyrosine; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1989 |
Identification and assay of phosphoserine and tyrosine-O-sulphate in fibrinopeptides by reversed-phase high-performance liquid chromatography.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Hydrolysis; Phosphates; Phosphoserine; Serine; Tyrosine | 1986 |
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Chromatography, Affinity; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Phosphoserine; Phosphothreonine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1988 |
Distribution of phosphoserine, phosphothreonine and phosphotyrosine in proteins of vesicular stomatitis virus.
Topics: Animals; Cells, Cultured; Cricetinae; Kidney; Mesocricetus; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Tyrosine; Vesicular stomatitis Indiana virus; Viral Proteins | 1981 |
Purified low-molecular-weight protein kinase from murine sarcoma virus particles catalyzes tyrosine phosphorylation endogenously but phosphorylates cellular proteins at serine.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Viral; Magnesium; Mice; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proteins; Sarcoma Viruses, Murine; Serine; Tyrosine | 1981 |
Phosphorylation and metabolism of the transforming protein of Rous sarcoma virus.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1982 |
Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.
Topics: Amino Acids; Animals; Insulin; Liver Neoplasms, Experimental; Macromolecular Substances; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptor, Insulin; Serine; Tyrosine | 1982 |
The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins.
Topics: Alpharetrovirus; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Chick Embryo; Molecular Weight; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins | 1982 |
Separation of phosphohydroxyamino acids by high-performance liquid chromatography.
Topics: Animals; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic AMP; Hydrolysis; Myelin Basic Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Serine; Threonine; Tyrosine | 1982 |
Two-dimensional separation of phosphoamino acids from nucleoside monophosphates.
Topics: Adenosine Monophosphate; Chromatography, Thin Layer; Cytidine Monophosphate; Electrophoresis; Escherichia coli; Guanosine Monophosphate; Nucleotides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Thymidine Monophosphate; Tyrosine; Uracil Nucleotides; Uridine Monophosphate | 1982 |
An acid phosphatase in the plasma membranes of human astrocytoma showing marked specificity toward phosphotyrosine protein.
Topics: Acid Phosphatase; Astrocytoma; Cell Line; Cell Membrane; Humans; Hydrogen-Ion Concentration; Neoplasms, Experimental; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphotyrosine; Substrate Specificity; Tyrosine | 1982 |
Dansylation and high-performance liquid chromatographic separation of phosphoserine, phosphothreonine and phosphotyrosine from 32P-labeled protein hydrolyzates.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Dansyl Compounds; Hydrolysis; In Vitro Techniques; Isotope Labeling; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Rats; Serine; Threonine; Tyrosine | 1982 |
A rapid microdetermination of phosphoserine, phosphothreonine, and phosphotyrosine in proteins by automatic cation exchange on a conventional amino acid analyzer.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Myocardium; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1983 |
The association of the transforming protein of Rous sarcoma virus with two cellular phosphoproteins.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chickens; Macromolecular Substances; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1983 |
Polyamide thin-layer chromatography of phosphorylated tyrosine, threonine, and serine.
Topics: Chromatography, Thin Layer; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1983 |
Appearance of functional EGF receptor kinase during rodent embryogenesis.
Topics: Age Factors; Animals; ErbB Receptors; Liver; Mice; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Rats; Tyrosine | 1983 |
Measurement of chemical phosphate in proteins.
Topics: Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphotyrosine; Proteins; Radioisotope Dilution Technique; Serine; Tyrosine | 1983 |
Two different protein kinase activities are associated with the insulin receptor.
Topics: Animals; Caseins; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Histones; In Vitro Techniques; Isoenzymes; Liver; Male; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine | 1983 |
Functional studies on the Rous sarcoma virus transforming gene product.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1984 |
Tyrosine protein kinase activity in normal rat tissues: brain.
Topics: Animals; Binding Sites; Brain; Cations, Divalent; Male; Nerve Tissue Proteins; Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Rats; Structure-Activity Relationship; Tyrosine | 1984 |
Calmodulin-stimulated phosphorylation of 17 beta-estradiol receptor on tyrosine.
Topics: Animals; Calmodulin; Cattle; Cell Nucleus; Cytosol; Enzyme Activation; Estradiol; Female; Kinetics; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Receptors, Estradiol; Receptors, Estrogen; Tyrosine; Uterus | 1984 |
Chemical properties, isolation, and analysis of O-phosphates in proteins.
Topics: Carbon Radioisotopes; Chemical Phenomena; Chemistry; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tritium; Tyrosine | 1984 |
Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptors.
Topics: Amino Acids; Animals; Cell Differentiation; Cell Division; Cell Line; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Macromolecular Substances; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptor Protein-Tyrosine Kinases; Receptors, Granulocyte Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Proteins; Transfection; Tyrosine | 1993 |
Synergistic control mechanism for abnormal site phosphorylation of Alzheimer's diseased brain tau by kinase FA/GSK-3 alpha.
Topics: Alzheimer Disease; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Glycogen Synthase Kinase 3; Humans; Kinetics; Microtubule-Associated Proteins; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Substrate Specificity; tau Proteins; Tyrosine | 1993 |
GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Dogs; ErbB Receptors; Erythrocytes; G(M3) Ganglioside; Humans; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Tumor Cells, Cultured; Tyrosine | 1994 |
Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B).
Topics: Amino Acid Sequence; Angiotensin II; Animals; Calcineurin; Calmodulin-Binding Proteins; Casein Kinases; Kinetics; Liver; Molecular Sequence Data; Phosphopeptides; Phosphoprotein Phosphatases; Phosphoserine; Phosphotyrosine; Protein Kinases; Rats; Substrate Specificity; Tyrosine | 1994 |
Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase.
Topics: 3-O-Methylglucose; Animals; Cell Line; Fibroblasts; Glucose; Humans; Insulin; Isoenzymes; Kinetics; Mannitol; Methylglucosides; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Rats; Receptor, Insulin; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1994 |
Multiple sites of phosphorylation within the alpha heavy chain of Chlamydomonas outer arm dynein.
Topics: Animals; Centrifugation, Density Gradient; Chlamydomonas; Dyneins; Flagella; Pancreatic Elastase; Peptide Fragments; Phosphates; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Trypsin; Tyrosine | 1994 |
Protein kinase C-dependent phosphorylation of a ciliary membrane protein and inhibition of ciliary beating.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Annexins; Carbazoles; Cell Fractionation; Cilia; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Erythrocytes; Indoles; Isoquinolines; Membrane Proteins; Movement; Phosphorylation; Phosphoserine; Phosphotyrosine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sheep; Tetradecanoylphorbol Acetate; Trachea; Tyrosine | 1993 |
Tyrosine and serine phosphorylation of dystrophin and the 58-kDa protein in the postsynaptic membrane of Torpedo electric organ.
Topics: Adenosine Triphosphate; Animals; Cell Fractionation; Centrifugation, Density Gradient; Dystrophin; Electric Organ; Electrophoresis, Polyacrylamide Gel; Membrane Proteins; Molecular Weight; Phosphoserine; Phosphotyrosine; Synaptic Membranes; Torpedo; Tyrosine | 1994 |
The angiotensin II AT1 receptor is tyrosine and serine phosphorylated and can serve as a substrate for the src family of tyrosine kinases.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Cloning, Molecular; Genes, src; Glutathione Transferase; Isoenzymes; Kinetics; Muscle, Smooth, Vascular; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Angiotensin; Recombinant Fusion Proteins; Substrate Specificity; Type C Phospholipases; Tyrosine | 1994 |
Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx.
Topics: Aluminum Compounds; Calcium; CD3 Complex; Cell Line; Cytokines; Fluorides; Glutathione; Humans; In Vitro Techniques; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Phosphotyrosine; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Terpenes; Thapsigargin; Tyrosine | 1994 |
Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung.
Topics: Adenocarcinoma; Amino Acid Sequence; Antibodies; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Casein Kinases; Caseins; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Kinetics; Lung; Lung Neoplasms; Molecular Sequence Data; Myelin Basic Protein; Peptides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Proteins; Substrate Specificity; Tyrosine | 1994 |
Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycogen Synthase Kinases; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Weight; Muscles; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Recombinant Proteins; Tyrosine | 1994 |
Bile acid efflux mediated by the rat liver canalicular bile acid transport/ecto-ATPase protein requires serine 503 phosphorylation and is regulated by tyrosine 488 phosphorylation.
Topics: Adenosine Triphosphatases; Alkaloids; Amino Acid Sequence; Amino Acids; Animals; Antigens, CD; Base Sequence; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cell Adhesion Molecules; Cells, Cultured; Consensus Sequence; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Phorbol Esters; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Rats; Staurosporine; Structure-Activity Relationship; Transfection; Tyrosine | 1994 |
Phosphorylation and identification of a major tyrosine phosphorylation site in protein tyrosine phosphatase 1C.
Topics: Amino Acid Sequence; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; Tyrosine | 1994 |
Protein-tyrosine phosphatase activity of CD45 is activated by sequential phosphorylation by two kinases.
Topics: Animals; Casein Kinase II; Cell Line; Cricetinae; Enzyme Activation; Humans; Leukocyte Common Antigens; Lymphocyte Activation; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; T-Lymphocytes; Time Factors; Tyrosine | 1994 |
Autophosphorylation-activated protein kinase inactivates the protein tyrosine phosphatase activity of protein phosphatase 2A.
Topics: Adenosine Triphosphate; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; ErbB Receptors; Glycogen Synthase Kinase 3; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protamine Kinase; Protein Kinases; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Recombinant Proteins; Substrate Specificity; Tyrosine | 1994 |
Determination of antigen-antibody affinity by immunocapillary electrophoresis.
Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Capillary Action; Electrophoresis; Hydrogen-Ion Concentration; Immunologic Techniques; Kinetics; Phosphoserine; Phosphotyrosine; Tyrosine | 1994 |
Platelet-derived growth factor stimulates phosphorylation of growth factor receptor-binding protein-2 in vascular smooth muscle cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cells, Cultured; ErbB Receptors; GRB2 Adaptor Protein; In Vitro Techniques; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; Rats; Signal Transduction; Tyrosine | 1994 |
Cloning and biochemical characterization of a plant protein kinase that phosphorylates serine, threonine, and tyrosine.
Topics: Arabidopsis; Arabidopsis Proteins; Base Sequence; Cloning, Molecular; DNA Primers; Molecular Sequence Data; Phosphoserine; Phosphothreonine; Phosphotyrosine; Plant Proteins; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 1994 |
Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and zeste-white 3 kinase.
Topics: Amino Acid Sequence; Animals; Armadillo Domain Proteins; Cell Adhesion; Consensus Sequence; Drosophila melanogaster; Drosophila Proteins; Glycogen Synthase Kinase 3; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Structure-Activity Relationship; Trans-Activators; Transcription Factors; Tyrosine; Wnt1 Protein | 1994 |
Protein kinase C and insulin receptor beta-subunit serine phosphorylation in cultured foetal rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Enzyme Activation; Glucose; Glycogen; Insulin; Liver; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Rats; Receptor, Insulin; Swine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Induction of serine and threonine protein phosphorylation by endotoxin-associated protein in murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Bacterial Proteins; Dinoprostone; Endotoxins; Female; Ionomycin; Lipid A; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
1H and 31P NMR spectroscopy of phosphorylated model peptides.
Topics: Amino Acid Sequence; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Phosphopeptides; Phosphorus; Phosphoserine; Phosphothreonine; Phosphotyrosine; Structure-Activity Relationship; Tyrosine | 1994 |
Selective phosphoamino acid enrichment by organic solvent fractionation.
Topics: Acetone; Chemical Fractionation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tyrosine | 1994 |
Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Macroglobulins; Animals; Base Sequence; DNA; DNA-Binding Proteins; Gene Expression Regulation; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-6; Isoquinolines; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphoserine; Phosphotyrosine; Piperazines; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine | 1995 |
Differential phosphorylation of a 57-KDa protein tyrosine kinase during egg activation.
Topics: Amino Acid Sequence; Animals; Antibodies; Cell Cycle; Electrophoresis, Polyacrylamide Gel; Female; Fertilization; Genes, src; Male; Molecular Sequence Data; Molecular Weight; Oocytes; Peptides; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Sea Urchins; Spermatozoa; Tyrosine | 1995 |
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine | 1995 |
Phosphorylation of dense-plaque proteins talin and paxillin during tracheal smooth muscle contraction.
Topics: Acetylcholine; Animals; Binding Sites; Cytoskeletal Proteins; Dogs; Immunosorbent Techniques; Muscle Contraction; Muscle, Smooth; Paxillin; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Talin; Trachea; Tyrosine; Vinculin | 1995 |
Dual modulation of phosphorylation of a 60 kDa nuclear protein in interferon-alpha treated Daudi cells.
Topics: B-Lymphocytes; Cell Line; Humans; Interferon alpha-2; Interferon-alpha; Molecular Weight; Nuclear Proteins; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tyrosine | 1995 |
In vivo and in vitro serine/threonine phosphorylations of epidermal growth factor receptor upon entry into the cell cycle.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Culture Media, Serum-Free; Electrophoresis, Gel, Two-Dimensional; ErbB Receptors; Flow Cytometry; Glioblastoma; Humans; Interphase; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; S Phase; Tyrosine | 1995 |
Nerve growth factor stimulates tyrosine phosphorylation of paxillin in PC12h cells.
Topics: Animals; Blotting, Western; Cell Adhesion Molecules; Cytochalasin D; Cytoskeletal Proteins; Immunosorbent Techniques; Kinetics; Nerve Growth Factors; Paxillin; PC12 Cells; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Signal Transduction; Tyrosine | 1995 |
Phosphatase resistance of ERK2 brain kinase PK40erk2.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Amino Acid Sequence; Animals; Brain; Cattle; Drug Resistance; Enzyme Activation; Isoenzymes; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Phosphates; Phosphoprotein Phosphatases; Phosphoserine; Phosphotyrosine; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Tyrosine | 1995 |
Tyrosine- versus serine-phosphorylation leads to conformational changes in a synthetic tau peptide.
Topics: Alzheimer Disease; Amino Acid Sequence; Antibodies, Monoclonal; Genes, Synthetic; Humans; Immunodominant Epitopes; Molecular Sequence Data; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Conformation; Protein Processing, Post-Translational; Spectroscopy, Fourier Transform Infrared; tau Proteins; Tyrosine | 1994 |
Phosphorylation of human plasminogen activators and plasminogen.
Topics: Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Humans; Immunoblotting; Melanoma; Phosphorylation; Phosphoserine; Phosphotyrosine; Plasminogen; Plasminogen Activators; Tissue Plasminogen Activator; Tumor Cells, Cultured; Tyrosine; Urokinase-Type Plasminogen Activator | 1995 |
The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane.
Topics: 3T3 Cells; Animals; Base Sequence; Cytoplasm; DNA Primers; Fluorescent Antibody Technique; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatases; Recombinant Proteins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Ganglioside GM1 binds to the Trk protein and regulates receptor function.
Topics: Animals; Cell Differentiation; G(M1) Ganglioside; Kinetics; Nerve Growth Factors; Neurites; Neurofilament Proteins; PC12 Cells; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Tyrosine | 1995 |
A new approach to phosphoserine, phosphothreonine and phosphotyrosine synthons and to thiophospho analogs. Stepwise synthesis of mono- and multiphosphorylated phosphopeptides related to src-protein kinase.
Topics: Amino Acid Sequence; CSK Tyrosine-Protein Kinase; Molecular Sequence Data; Organothiophosphates; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine | 1995 |
In vitro binding and phosphorylation of human immunodeficiency virus type 1 Nef protein by serine/threonine protein kinase.
Topics: Base Sequence; Binding Sites; Cell Line; DNA Primers; Gene Products, nef; Genes, nef; Glutathione Transferase; HIV-1; Humans; Kinetics; Molecular Sequence Data; nef Gene Products, Human Immunodeficiency Virus; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Sequence Deletion; Tyrosine | 1995 |
Analysis of phosphorylhydroxyamino acids present in hydrolyzed cell extracts using dabsyl derivatization.
Topics: Cell Extracts; Chromatography, Thin Layer; Electrophoresis; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; p-Dimethylaminoazobenzene; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Protein-Tyrosine Kinases; Quercetin; Tumor Cells, Cultured; Tyrosine | 1995 |
Studies into the identity of the sites of insulin-stimulated insulin receptor serine phosphorylation. Characterization of synthetic peptide substrates for the insulin-stimulated insulin receptor serine kinase.
Topics: Amino Acid Sequence; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insulin; Molecular Sequence Data; Peptide Mapping; Phosphopeptides; Phosphoserine; Phosphotyrosine; Placenta; Pregnancy; Receptor, Insulin; Serine; Substrate Specificity; Trypsin; Tyrosine | 1995 |
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Chlorocebus aethiops; Conserved Sequence; DNA-Binding Proteins; Gene Expression Regulation; Humans; Luciferases; Mice; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphotyrosine; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine | 1995 |
Protein phosphorylation on serine, threonine, and tyrosine residues modulates membrane-protein interactions and transcriptional regulation in Salmonella typhimurium.
Topics: Adenosine Triphosphate; Bacterial Proteins; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Bacterial; Magnetic Resonance Spectroscopy; Membrane Proteins; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Kinases; Protein-Tyrosine Kinases; Salmonella typhimurium; Tyrosine | 1995 |
Identification of Lck-binding elements in tip of herpesvirus saimiri.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Chlorocebus aethiops; DNA Primers; Herpesvirus 2, Saimiriine; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Point Mutation; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Spodoptera; Structure-Activity Relationship; Transfection; Tyrosine; Viral Proteins | 1995 |
The phosphoinositide 3-kinase inhibitor wortmannin inhibits CD28-mediated T cell co-stimulation.
Topics: Androstadienes; Animals; CD28 Antigens; Cell Line; CHO Cells; Cricetinae; Enzyme Inhibitors; Humans; Lymphocyte Activation; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; T-Lymphocytes; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1995 |
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Colforsin; Diacylglycerol Kinase; Epidermal Growth Factor; Epitopes; ErbB Receptors; Escherichia coli; Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1993 |
SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells.
Topics: Animals; Cell Differentiation; Mitogens; Nerve Growth Factors; Neurons; Nuclear Proteins; Oncogene Protein pp60(v-src); Oncogenes; PC12 Cells; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Tyrosine | 1993 |
Negative regulation of the wee1 protein kinase by direct action of the nim1/cdr1 mitotic inducer.
Topics: Animals; Baculoviridae; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Escherichia coli; Fungal Proteins; Moths; Nuclear Proteins; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine | 1993 |
Atrial natriuretic factor stimulates phosphorylation of a 52-kDa calmodulin-binding protein in vascular smooth muscle cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Calmodulin-Binding Proteins; Cells, Cultured; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Endothelins; Male; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Rats; Rats, Inbred Strains; Rats, Wistar; Tyrosine | 1993 |
Phosphorylation of recombinant non-NMDA glutamate receptors on serine and tyrosine residues.
Topics: Cell Line; Embryo, Mammalian; Gene Expression; Humans; Immunosorbent Techniques; Kidney; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Glutamate; Recombinant Proteins; Transfection; Tyrosine | 1993 |
Identification of O-phosphoamino acids in urine hydrolysate by gas chromatography-mass spectrometry.
Topics: Amino Acids; Chromatography, DEAE-Cellulose; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Phosphoserine; Phosphothreonine; Phosphotyrosine; Photometry; Tyrosine | 1993 |
Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinases.
Topics: Animals; Cell Transformation, Viral; Chick Embryo; DNA Mutational Analysis; Gene Expression Regulation, Enzymologic; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tyrosine; Urokinase-Type Plasminogen Activator | 1993 |
Distinct beta-subunits are present in hybrid insulin-like-growth-factor-1 receptors in the central nervous system.
Topics: Animals; Brain Chemistry; Insulin-Like Growth Factor I; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphotyrosine; Precipitin Tests; Rats; Receptor, IGF Type 1; Receptor, Insulin; Synaptosomes; Tyrosine | 1993 |
Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo.
Topics: Actin Cytoskeleton; Animals; Cell Compartmentation; Cell Division; Concanavalin A; Cytoskeleton; Dictyostelium; Membrane Proteins; Mutation; Myosins; Octoxynol; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Tyrosine | 1993 |
Phosphorylation of two human neurochordins by mammalian casein kinase 1.
Topics: Adenosine Triphosphate; Adolescent; Autoradiography; Brain; Casein Kinases; Electrophoresis, Polyacrylamide Gel; Female; Humans; Membrane Glycoproteins; Molecular Weight; Nerve Tissue Proteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine | 1993 |
Dynamics of connexin43 phosphorylation in pp60v-src-transformed cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Line, Transformed; Connexin 43; Fibroblasts; Immunosorbent Techniques; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; RNA, Messenger; Transformation, Genetic; Tyrosine | 1993 |
Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages.
Topics: Amino Acids; Cell Differentiation; DNA-Binding Proteins; Gene Expression Regulation; Interferon-Stimulated Gene Factor 3; Janus Kinase 1; Janus Kinase 2; Macrophages; Models, Biological; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Serine; STAT1 Transcription Factor; Trans-Activators; Transcription Factors; Tyrosine | 1995 |
CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor.
Topics: Amino Acid Sequence; CD3 Complex; Cell Line; Coated Pits, Cell-Membrane; Down-Regulation; Endocytosis; Enzyme Activation; Humans; Leucine; Molecular Sequence Data; Phosphorylation; Phosphoserine; Point Mutation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes; Transfection; Tyrosine | 1994 |
Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells.
Topics: Androstadienes; Animals; Cell Line; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver Neoplasms, Experimental; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Rats; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1996 |
Characterization of the C-terminal domain of ras-GTPase-activating protein (ras-GAP) as substrate for epidermal growth factor receptor and p60c-src kinase.
Topics: Electrophoresis, Polyacrylamide Gel; Enzyme Activation; ErbB Receptors; GTPase-Activating Proteins; Histones; Humans; Kinetics; Magnesium; Manganese; Ovalbumin; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyglutamic Acid; Polylysine; Proteins; ras GTPase-Activating Proteins; src-Family Kinases; Trypsin; Tumor Cells, Cultured; Tyrosine | 1996 |
Evidence that tyrosine phosphorylation regulates N-cadherin turnover during retinal development.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Cadherins; Chick Embryo; Enzyme Inhibitors; Heart; Hydrogen Peroxide; Isoquinolines; Lens, Crystalline; Myocardium; Organ Culture Techniques; Peptide Mapping; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Retina; Sulfonamides; Tyrosine; Vanadates | 1997 |
Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Alanine; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Insulin; Insulin-Like Growth Factor I; Isoenzymes; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Transfection; Tyrosine | 1997 |
Dual specificity of the interleukin 1- and tumor necrosis factor-activated beta casein kinase.
Topics: Amino Acid Sequence; Casein Kinases; Enzyme Activation; Humans; Interleukin-1; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphoserine; Protein Kinases; Signal Transduction; Structure-Activity Relationship; Substrate Specificity; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 1997 |
Phosphorylation of Tyr7, Tyr10, and Ser27 of alpha-chain in H+,K(+)-ATPase by intrinsic and extrinsic kinases.
Topics: Animals; Cholic Acids; Detergents; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Serine; Swine; Tyrosine | 1997 |
Cellular compartmentalization in insulin action: altered signaling by a lipid-modified IRS-1.
Topics: Cell Compartmentation; Cell Division; Cell Line; Cell Membrane; Enzyme Activation; Gene Expression; Insulin; Insulin Receptor Substrate Proteins; Lipid Metabolism; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Ribosomal Protein S6 Kinases; Signal Transduction; Subcellular Fractions; Tyrosine | 2000 |
Ser133 phosphate-KIX interactions in the CREB-CBP complex: an ab initio molecular dynamics study.
Topics: Binding Sites; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Phosphoserine; Protein Conformation; Protein Structure, Secondary; Quantum Theory; Static Electricity; Time Factors; Trans-Activators; Tyrosine | 2001 |
Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins.
Topics: 14-3-3 Proteins; 3T3 Cells; Amino Acid Motifs; Animals; Cell Line; Cloning, Molecular; DNA-Binding Proteins; Genetic Vectors; Glutathione Transferase; Humans; Ligands; MAP Kinase Signaling System; Mice; Milk Proteins; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Okadaic Acid; Phosphorylation; Phosphoserine; Phosphothreonine; Plasmids; Precipitin Tests; Prolactin; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Prolactin; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Threonine; Time Factors; Trans-Activators; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrosine; Tyrosine 3-Monooxygenase | 2003 |
Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1.
Topics: Animals; Cyclin-Dependent Kinases; Cyclins; Meiosis; Mutagenesis, Site-Directed; Mutation; Oocytes; Peptides; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine; Xenopus; Xenopus Proteins | 2006 |
A sulfated, phosphorylated 7 kDa secreted peptide characterized by direct analysis of cell culture media.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cattle; Cell Line, Tumor; Chromogranin B; Culture Media, Conditioned; Dogs; Humans; Mice; Molecular Sequence Data; Neuropeptides; Phosphopeptides; Phosphorylation; Phosphoserine; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfuric Acid Esters; Tyrosine | 2008 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.
Topics: Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Phosphoserine; Protein Folding; Protein Processing, Post-Translational; Serine; Threonine; Tryptophan; Tyrosine | 2009 |
Src activation by β-adrenoreceptors is a key switch for tumour metastasis.
Topics: Adrenergic beta-Antagonists; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Mice; Models, Molecular; Neoplasm Invasiveness; Neoplasm Metastasis; Norepinephrine; Ovarian Neoplasms; Phosphorylation; Phosphoserine; Receptors, Adrenergic, beta; Signal Transduction; src-Family Kinases; Stress, Physiological; Survival Analysis; Tyrosine | 2013 |
Hydrogen bond strengths in phosphorylated and sulfated amino acid residues.
Topics: Amino Acids; Arginine; Computational Biology; Databases, Protein; Glutamic Acid; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Peptides; Phosphates; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Processing, Post-Translational; Proteins; Solvents; Static Electricity; Tyrosine | 2013 |
Transcriptomic and metabolomic analyses reveal the main metabolites in Dendrobium officinale leaves during the harvesting period.
Topics: Alanine; Dendrobium; Flavonoids; Glucose; Mannose; Monosaccharides; Phosphoserine; Polysaccharides; Rutin; Transcriptome; Tyrosine; Water | 2022 |
At low levels, inorganic mercury interference with antigen signaling is associated with modifications to a panel of novel phosphoserine sites in B cell receptor pathway proteins.
Topics: Animals; Cell Line; Chromatography, Liquid; Humans; Mercury; Mice; Phosphorylation; Phosphoserine; Proteins; Proteomics; Receptors, Antigen, B-Cell; Signal Transduction; Tandem Mass Spectrometry; Tyrosine | 2023 |